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    Ellen Breen

    TitleAssociate Researcher
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0623-A
    CA La Jolla 92093
    Phone858-822-5859
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Breen E, Scadeng M, Lai NC, Murray F, Bigby TD. Functional magnetic resonance imaging for In Vivo quantification of pulmonary hypertension in the Sugen 5416/hypoxia mouse. Exp Physiol. 2016 Nov 29. PMID: 27897352.
        View in: PubMed
      2. Tang K, Gu Y, Dalton ND, Wagner H, Peterson KL, Wagner PD, Breen E. Selective Life-Long Skeletal Myofiber-Targeted VEGF Gene Ablation Impairs Exercise Capacity in Adult Mice. J Cell Physiol. 2016 Feb; 231(2):505-11. PMID: 26201683.
        View in: PubMed
      3. Huey KA, Smith SA, Sulaeman A, Breen E. Skeletal myofiber VEGF is necessary for myogenic and contractile adaptations to functional overload of the plantaris in adult mice. J Appl Physiol (1985). 2016 Jan 15; 120(2):188-95. PMID: 26542520.
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      4. Darquenne C, Borja MG, Oakes JM, Breen E, Olfert IM, Scadeng M, Prisk GK. Increase in relative deposition of fine particles in the rat lung periphery in the absence of gravity. J Appl Physiol (1985). 2014 Oct 15; 117(8):880-6. PMID: 25170069.
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      5. Oakes JM, Breen E, Scadeng M, Tchantchou GS, Darquenne C. MRI-based measurements of aerosol deposition in the lung of healthy and elastase-treated rats. J Appl Physiol (1985). 2014 Jun 15; 116(12):1561-8. PMID: 24790020.
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      6. Delavar H, Nogueira L, Wagner PD, Hogan MC, Metzger D, Breen E. Skeletal myofiber VEGF is essential for the exercise training response in adult mice. Am J Physiol Regul Integr Comp Physiol. 2014 Apr; 306(8):R586-95. PMID: 24523345.
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      7. Tang K, Murano G, Wagner H, Nogueira L, Wagner PD, Tang A, Dalton ND, Gu Y, Peterson KL, Breen E. Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation. J Appl Physiol (1985). 2013 May; 114(9):1340-50. PMID: 23449936.
        View in: PubMed
      8. Breen E, Malloy JL, Tang K, Xia F, Fu Z, Hancock RE, Overhage J, Wagner PD, Spragg RG. Impaired pulmonary defense against Pseudomonas aeruginosa in VEGF gene inactivated mouse lung. J Cell Physiol. 2013 Feb; 228(2):371-9. PMID: 22718316.
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      9. Oakes JM, Scadeng M, Breen E, Prisk GK, Darquenne C. Regional distribution of aerosol deposition in rat lungs using magnetic resonance imaging. Ann Biomed Eng. 2013 May; 41(5):967-78. PMID: 23354670.
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      10. Oakes JM, Scadeng M, Breen E, Marsden AL, Darquenne C. Rat airway morphometry measured from in situ MRI-based geometric models. J Appl Physiol (1985). 2012 Jun; 112(11):1921-31. PMID: 22461437.
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      11. Olfert IM, Howlett RA, Wagner PD, Breen E. Myocyte vascular endothelial growth factor is required for exercise-induced skeletal muscle angiogenesis. Am J Physiol Regul Integr Comp Physiol. 2010 Oct; 299(4):R1059-67. PMID: 20686173.
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      12. Tang K, Wagner PD, Breen E. TNF-alpha-mediated reduction in PGC-1alpha may impair skeletal muscle function after cigarette smoke exposure. J Cell Physiol. 2010 Feb; 222(2):320-7. PMID: 19859910.
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      13. Tang K, Xia FC, Wagner PD, Breen E. Exercise-induced VEGF transcriptional activation in brain, lung and skeletal muscle. Respir Physiol Neurobiol. 2010 Jan 31; 170(1):16-22. PMID: 19853064.
        View in: PubMed
      14. Olfert IM, Howlett RA, Tang K, Dalton ND, Gu Y, Peterson KL, Wagner PD, Breen E. Muscle-specific VEGF deficiency greatly reduces exercise endurance in mice. J Physiol. 2009 Apr 15; 587(Pt 8):1755-67. PMID: 19237429.
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      15. Rossiter HB, Breen E. Commentaries on viewpoint: use of mean airspace chord length to assess emphysema. Assessment of emphysema benefits from quantification of heterogeneity. J Appl Physiol (1985). 2008 Dec; 105(6):1983-4; author reply 1986-7. PMID: 19140248.
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      16. Baker ME, Ruggeri B, Sprague LJ, Eckhardt-Ludka C, Lapira J, Wick I, Soverchia L, Ubaldi M, Polzonetti-Magni AM, Vidal-Dorsch D, Bay S, Gully JR, Reyes JA, Kelley KM, Schlenk D, Breen E, Sásik R, Hardiman G. Analysis of endocrine disruption in Southern California coastal fish using an aquatic multispecies microarray. Environ Health Perspect. 2009 Feb; 117(2):223-30. PMID: 19270792.
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      17. Rossiter HB, Scadeng M, Tang K, Wagner PD, Breen E. Doxycycline treatment prevents alveolar destruction in VEGF-deficient mouse lung. J Cell Biochem. 2008 May 15; 104(2):525-35. PMID: 18181212.
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      18. Breen E, Tang K, Olfert M, Knapp A, Wagner P. Skeletal muscle capillarity during hypoxia: VEGF and its activation. High Alt Med Biol. 2008; 9(2):158-66. PMID: 18578647.
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      19. Breen E. VEGF in biological control. J Cell Biochem. 2007 Dec 15; 102(6):1358-67. PMID: 17979153.
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      20. Scadeng M, Rossiter HB, Dubowitz DJ, Breen E. High-resolution three-dimensional magnetic resonance imaging of mouse lung in situ. Invest Radiol. 2007 Jan; 42(1):50-7. PMID: 17213749.
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      21. Olfert IM, Breen E, Gavin TP, Wagner PD. Temporal thrombospondin-1 mRNA response in skeletal muscle exposed to acute and chronic exercise. Growth Factors. 2006 Dec; 24(4):253-9. PMID: 17381066.
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      22. Wagner PD, Olfert IM, Tang K, Breen E. Muscle-targeted deletion of VEGF and exercise capacity in mice. Respir Physiol Neurobiol. 2006 Apr 28; 151(2-3):159-66. PMID: 16344007.
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      23. Tang K, Breen E, Wagner H, Brutsaert TD, Gassmann M, Wagner PD. HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius. Respir Physiol Neurobiol. 2004 Nov 30; 144(1):71-80. PMID: 15522704.
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      24. Tang K, Rossiter HB, Wagner PD, Breen E. Lung-targeted VEGF inactivation leads to an emphysema phenotype in mice. J Appl Physiol (1985). 2004 Oct; 97(4):1559-66; discussion 1549. PMID: 15208295.
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      25. Tang K, Breen E, Gerber HP, Ferrara NM, Wagner PD. Capillary regression in vascular endothelial growth factor-deficient skeletal muscle. Physiol Genomics. 2004 Jun 17; 18(1):63-9. PMID: 15084712.
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      26. Breen E, Tang K. Calcyclin (S100A6) regulates pulmonary fibroblast proliferation, morphology, and cytoskeletal organization in vitro. J Cell Biochem. 2003 Mar 1; 88(4):848-54. PMID: 12577318.
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      27. Tang K, Breen E, Wagner PD. Hu protein R-mediated posttranscriptional regulation of VEGF expression in rat gastrocnemius muscle. Am J Physiol Heart Circ Physiol. 2002 Oct; 283(4):H1497-504. PMID: 12234802.
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      28. Brutsaert TD, Gavin TP, Fu Z, Breen E, Tang K, Mathieu-Costello O, Wagner PD. Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation. BMC Physiol. 2002 Jun 19; 2:8. PMID: 12086595.
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      29. Olfert IM, Breen E, Mathieu-Costello O, Wagner PD. Skeletal muscle capillarity and angiogenic mRNA levels after exercise training in normoxia and chronic hypoxia. J Appl Physiol (1985). 2001 Sep; 91(3):1176-84. PMID: 11509513.
        View in: PubMed
      30. Siafakas NM, Jordan M, Wagner H, Breen E, Benoit H, Wagner PD. Diaphragmatic angiogenic growth factor mRNA responses to increased ventilation caused by hypoxia and hypercapnia. Eur Respir J. 2001 Apr; 17(4):681-7. PMID: 11401064.
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      31. Olfert IM, Breen E, Mathieu-Costello O, Wagner PD. Chronic hypoxia attenuates resting and exercise-induced VEGF, flt-1, and flk-1 mRNA levels in skeletal muscle. J Appl Physiol (1985). 2001 Apr; 90(4):1532-8. PMID: 11247956.
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      32. Gavin TP, Spector DA, Wagner H, Breen E, Wagner PD. Effect of captopril on skeletal muscle angiogenic growth factor responses to exercise. J Appl Physiol (1985). 2000 May; 88(5):1690-7. PMID: 10797131.
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      33. Gavin TP, Spector DA, Wagner H, Breen E, Wagner PD. Nitric oxide synthase inhibition attenuates the skeletal muscle VEGF mRNA response to exercise. J Appl Physiol (1985). 2000 Apr; 88(4):1192-8. PMID: 10749807.
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      34. Breen E. Mechanical strain increases type I collagen expression in pulmonary fibroblasts in vitro. J Appl Physiol (1985). 2000 Jan; 88(1):203-9. PMID: 10642382.
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      35. Breen E, Fu Z, Normand H. Calcyclin gene expression is increased by mechanical strain in fibroblasts and lung. Am J Respir Cell Mol Biol. 1999 Dec; 21(6):746-52. PMID: 10572072.
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      36. Berg JT, Breen E, Fu Z, Mathieu-Costello O, West JB. Alveolar hypoxia increases gene expression of extracellular matrix proteins and platelet-derived growth factor-B in lung parenchyma. Am J Respir Crit Care Med. 1998 Dec; 158(6):1920-8. PMID: 9847287.
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      37. Roca J, Gavin TP, Jordan M, Siafakas N, Wagner H, Benoit H, Breen E, Wagner PD. Angiogenic growth factor mRNA responses to passive and contraction-induced hyperperfusion in skeletal muscle. J Appl Physiol (1985). 1998 Sep; 85(3):1142-9. PMID: 9729593.
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      38. Parker JC, Breen E, West JB. High vascular and airway pressures increase interstitial protein mRNA expression in isolated rat lungs. J Appl Physiol (1985). 1997 Nov; 83(5):1697-705. PMID: 9375341.
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      39. Berg JT, Fu Z, Breen E, Tran HC, Mathieu-Costello O, West JB. High lung inflation increases mRNA levels of ECM components and growth factors in lung parenchyma. J Appl Physiol (1985). 1997 Jul; 83(1):120-8. PMID: 9216953.
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      40. Breen E, Johnson EC, Wagner H, Tseng HM, Sung LA, Wagner PD. Angiogenic growth factor mRNA responses in muscle to a single bout of exercise. J Appl Physiol (1985). 1996 Jul; 81(1):355-61. PMID: 8828685.
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      41. Breen E, van Wijnen AJ, Lian JB, Stein GS, Stein JL. In vivo occupancy of the vitamin D responsive element in the osteocalcin gene supports vitamin D-dependent transcriptional upregulation in intact cells. Proc Natl Acad Sci U S A. 1994 Dec 20; 91(26):12902-6. PMID: 7809144.
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      42. Breen E, Ignotz RA, McCabe L, Stein JL, Stein GS, Lian JB. TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype. J Cell Physiol. 1994 Aug; 160(2):323-35. PMID: 8040190.
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      43. Breen E, Shull S, Burne S, Absher M, Kelley J, Phan S, Cutroneo KR. Bleomycin regulation of transforming growth factor-beta mRNA in rat lung fibroblasts. Am J Respir Cell Mol Biol. 1992 Feb; 6(2):146-52. PMID: 1371688.
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      44. Schepmoes G, Breen E, Owen TA, Aronow MA, Stein GS, Lian JB. Influence of dexamethasone on the vitamin D-mediated regulation of osteocalcin gene expression. J Cell Biochem. 1991 Oct; 47(2):184-96. PMID: 1757481.
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      45. Breen E, Falco VM, Absher M, Cutroneo KR. Subpopulations of rat lung fibroblasts with different amounts of type I and type III collagen mRNAs. J Biol Chem. 1990 Apr 15; 265(11):6286-90. PMID: 2180946.
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