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PGAP3 regulates human bronchial epithelial cell mRNAs present in asthma and respiratory virus reference data sets. medRxiv. 2024 Jul 06.
Leslie E, Miller M, Lafuze A, Svyatskaya S, Choi GS, Broide DH. PMID: 39006429; PMCID: PMC11245055.
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Lymphotoxin beta receptor signaling directly controls airway smooth muscle deregulation and asthmatic lung dysfunction. J Allergy Clin Immunol. 2023 04; 151(4):976-990.e5.
Miki H, Kiosses WB, Manresa MC, Gupta RK, Sethi GS, Herro R, Da Silva Antunes R, Dutta P, Miller M, Fung K, Chawla A, Dobaczewska K, Ay F, Broide DH, Tumanov AV, Croft M. PMID: 36473503; PMCID: PMC10081945.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Insights into the biology of IL-9 in asthma. J Allergy Clin Immunol. 2022 09; 150(3):585-586.
Doherty TA, Broide DH. PMID: 35662655; PMCID: PMC9463120.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Reduced AIBP expression in bronchial epithelial cells of asthmatic patients: Potential therapeutic target. Clin Exp Allergy. 2022 08; 52(8):979-984.
Miller M, Pham AK, Gonen A, Navia-Pelaez JM, Xia K, Park S, Osterman AL, Bacon K, Beaton G, Kurten RC, Broide DH, Miller YI. PMID: 35460293; PMCID: PMC10241564.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Single-base editing of rs12603332 on chromosome 17q21 with a cytosine base editor regulates ORMDL3 and ATF6α expression. Allergy. 2022 04; 77(4):1139-1149.
Weng N, Miller M, Pham AK, Komor AC, Broide DH. PMID: 34525218; PMCID: PMC8920947.
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PubMed Mentions: Fields:
Translation:
HumansCells
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ORMDL3 expression in ASM regulates hypertrophy, hyperplasia via TPM1 and TPM4, and contractility. JCI Insight. 2021 04 08; 6(7).
Pham AK, Miller M, Rosenthal P, Das S, Weng N, Jang S, Kurten RC, Badrani J, Doherty TA, Oliver B, Broide DH. PMID: 33661765; PMCID: PMC8119187.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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TL1A Promotes Lung Tissue Fibrosis and Airway Remodeling. J Immunol. 2020 11 01; 205(9):2414-2422.
Herro R, Miki H, Sethi GS, Mills D, Mehta AK, Nguyen XX, Feghali-Bostwick C, Miller M, Broide DH, Soloff R, Croft M. PMID: 32958689; PMCID: PMC7577982.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Chromosome 17q21 SNP rs8076131 risk allele associates with airway smooth muscle hypertrophy in fatal asthma. Clin Exp Allergy. 2020 11; 50(11):1270-1273.
Miller M, Rosenthal P, Weng N, Pham A, Hur GY, Elliot J, Green FHY, James A, Broide DH. PMID: 32672387; PMCID: PMC7606767.
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PubMed Mentions: Fields:
Translation:
HumansCells
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ORMDL3 but not neighboring 17q21 gene LRRC3C is expressed in human lungs and lung cells of asthmatics. Allergy. 2020 08; 75(8):2061-2065.
Hur GY, Pham A, Miller M, Weng N, Hu J, Kurten RC, Broide DH. PMID: 32086831; PMCID: PMC7387186.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses. Elife. 2020 02 04; 9.
Lee J, Zhang J, Chung YJ, Kim JH, Kook CM, González-Navajas JM, Herdman DS, Nürnberg B, Insel PA, Corr M, Mo JH, Tao A, Yasuda K, Rifkin IR, Broide DH, Sciammas R, Webster NJ, Raz E. PMID: 32014112; PMCID: PMC7000221.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Genes and Pathways Regulating Decline in Lung Function and Airway Remodeling in Asthma. Allergy Asthma Immunol Res. 2019 Sep; 11(5):604-621.
Hur GY, Broide DH. PMID: 31332973; PMCID: PMC6658410.
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PubMed Mentions:
36
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Unconventional ST2- and CD127-negative lung ILC2 populations are induced by the fungal allergen Alternaria alternata. J Allergy Clin Immunol. 2019 11; 144(5):1432-1435.e9.
Cavagnero KJ, Badrani JH, Naji LH, Amadeo MB, Shah VS, Gasparian S, Pham A, Wang AW, Seumois G, Croft M, Broide DH, Doherty TA. PMID: 31369800; PMCID: PMC6938690.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Platelets attach to lung type 2 innate lymphoid cells (ILC2s) expressing P-selectin glycoprotein ligand 1 and influence ILC2 function. J Allergy Clin Immunol. 2019 10; 144(4):1112-1115.e8.
Karta MR, Cavagnero K, Miller M, Badrani J, Naji L, Doherty TA, Broide DH. PMID: 31201889; PMCID: PMC6779509.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Why Is ORMDL3 on Chromosome 17q21 Highly Linked to Asthma? Am J Respir Crit Care Med. 2019 Feb 15; 199(4):404-406.
Miller M, Broide DH. PMID: 30365391; PMCID: PMC6376625.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Airway innate lymphoid cells in the induction and regulation of allergy. Allergol Int. 2019 Jan; 68(1):9-16.
Doherty TA, Broide DH. PMID: 30473412; PMCID: PMC6614863.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 496 adults from San Diego, California, USA. Hum Immunol. 2018 Dec; 79(12):821-822.
Moore E, Grifoni A, Weiskopf D, Schulten V, Arlehamn CSL, Angelo M, Pham J, Leary S, Sidney J, Broide D, Frazier A, Phillips E, Mallal S, Mack SJ, Sette A. PMID: 30278218; PMCID: PMC6537871.
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PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Does reduced zona pellucida binding protein 2 (ZPBP2) expression on chromosome 17q21 protect against asthma? J Allergy Clin Immunol. 2018 08; 142(2):706-709.e4.
Miller M, Vuong C, Garcia MF, Rosenthal P, Das S, Weng N, Pham A, Kim YJ, Broide DH. PMID: 29709669; PMCID: PMC6078789.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Lipid regulation of group 2 innate lymphoid cell function: Moving beyond epithelial cytokines. J Allergy Clin Immunol. 2018 05; 141(5):1587-1589.
Doherty TA, Broide DH. PMID: 29522852; PMCID: PMC5967253.
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PubMed Mentions:
18 Fields:
Translation:
HumansCells
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Tumor necrosis factor family member LIGHT acts with IL-1β and TGF-β to promote airway remodeling during rhinovirus infection. Allergy. 2018 Jul; 73(7):1415-1424.
Mehta AK, Doherty T, Broide D, Croft M. PMID: 29315623; PMCID: PMC6019192.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Activating transcription factor 6α (ATF6α) regulates airway hyperreactivity, smooth muscle proliferation, and contractility. J Allergy Clin Immunol. 2018 01; 141(1):439-442.e4.
Unno H, Miller M, Rosenthal P, Beppu A, Das S, Broide DH. PMID: 28958904; PMCID: PMC5758405.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Orosomucoid-like 3 (ORMDL3) upregulates airway smooth muscle proliferation, contraction, and Ca2+ oscillations in asthma. J Allergy Clin Immunol. 2018 07; 142(1):207-218.e6.
Chen J, Miller M, Unno H, Rosenthal P, Sanderson MJ, Broide DH. PMID: 28889952; PMCID: PMC5842097.
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PubMed Mentions:
41 Fields:
Translation:
HumansAnimalsCells
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Rhinovirus Infection of ORMDL3 Transgenic Mice Is Associated with Reduced Rhinovirus Viral Load and Airway Inflammation. J Immunol. 2017 10 01; 199(7):2215-2224.
Song DJ, Miller M, Beppu A, Rosenthal P, Das S, Karta M, Vuong C, Mehta AK, Croft M, Broide DH. PMID: 28827284; PMCID: PMC5605463.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Chromosome 17q21 Genes ORMDL3 and GSDMB in Asthma and Immune Diseases. Adv Immunol. 2017; 135:1-52.
Das S, Miller M, Broide DH. PMID: 28826527.
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PubMed Mentions:
60 Fields:
Translation:
HumansAnimalsCells
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Leukotriene C4 Potentiates IL-33-Induced Group 2 Innate Lymphoid Cell Activation and Lung Inflammation. J Immunol. 2017 08 01; 199(3):1096-1104.
Lund SJ, Portillo A, Cavagnero K, Baum RE, Naji LH, Badrani JH, Mehta A, Croft M, Broide DH, Doherty TA. PMID: 28667163; PMCID: PMC5531601.
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PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
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Autophagy plays a role in FSTL1-induced epithelial mesenchymal transition and airway remodeling in asthma. Am J Physiol Lung Cell Mol Physiol. 2017 07 01; 313(1):L27-L40.
Liu T, Liu Y, Miller M, Cao L, Zhao J, Wu J, Wang J, Liu L, Li S, Zou M, Xu J, Broide DH, Dong L. PMID: 28473327.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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β2 integrins rather than β1 integrins mediate Alternaria-induced group 2 innate lymphoid cell trafficking to the lung. J Allergy Clin Immunol. 2018 01; 141(1):329-338.e12.
Karta MR, Rosenthal PS, Beppu A, Vuong CY, Miller M, Das S, Kurten RC, Doherty TA, Broide DH. PMID: 28366795; PMCID: PMC5623168.
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PubMed Mentions:
43 Fields:
Translation:
HumansAnimalsCells
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Cutting Edge: Targeting Epithelial ORMDL3 Increases, Rather than Reduces, Airway Responsiveness and Is Associated with Increased Sphingosine-1-Phosphate. J Immunol. 2017 04 15; 198(8):3017-3022.
Miller M, Tam AB, Mueller JL, Rosenthal P, Beppu A, Gordillo R, McGeough MD, Vuong C, Doherty TA, Hoffman HM, Niwa M, Broide DH. PMID: 28275141; PMCID: PMC5399887.
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PubMed Mentions:
31 Fields:
Translation:
Animals
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Group 2 innate lymphoid cells are recruited to the nasal mucosa in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2017 Jul; 140(1):101-108.e3.
Eastman JJ, Cavagnero KJ, Deconde AS, Kim AS, Karta MR, Broide DH, Zuraw BL, White AA, Christiansen SC, Doherty TA. PMID: 28279492; PMCID: PMC5496786.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Hypoxia-inducible factor-1α inhibition modulates airway hyperresponsiveness and nitric oxide levels in a BALB/c mouse model of asthma. Clin Immunol. 2017 03; 176:94-99.
Dewitz C, McEachern E, Shin S, Akong K, Nagle DG, Broide DH, Akuthota P, Crotty Alexander LE. PMID: 28093362.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Pathways to limit group 2 innate lymphoid cell activation. J Allergy Clin Immunol. 2017 05; 139(5):1465-1467.
Doherty TA, Broide DH. PMID: 28087226; PMCID: PMC5605226.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
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Acute renal dysfunction caused by nonsucrose intravenous immunoglobulin in common variable immunodeficiency. Ann Allergy Asthma Immunol. 2017 Feb; 118(2):231-233.
Kim AS, Broide DH. PMID: 28024991.
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PubMed Mentions:
2 Fields:
Translation:
Humans
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Oroscomucoid like protein 3 (ORMDL3) transgenic mice have reduced levels of sphingolipids including sphingosine-1-phosphate and ceramide. J Allergy Clin Immunol. 2017 04; 139(4):1373-1376.e4.
Miller M, Rosenthal P, Beppu A, Gordillo R, Broide DH. PMID: 27826095; PMCID: PMC5385289.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimals
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GSDMB induces an asthma phenotype characterized by increased airway responsiveness and remodeling without lung inflammation. Proc Natl Acad Sci U S A. 2016 11 15; 113(46):13132-13137.
Das S, Miller M, Beppu AK, Mueller J, McGeough MD, Vuong C, Karta MR, Rosenthal P, Chouiali F, Doherty TA, Kurten RC, Hamid Q, Hoffman HM, Broide DH. PMID: 27799535; PMCID: PMC5135378.
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PubMed Mentions:
107 Fields:
Translation:
HumansAnimalsCells
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Transcriptional Profiling of Th2 Cells Identifies Pathogenic Features Associated with Asthma. J Immunol. 2016 07 15; 197(2):655-64.
Seumois G, Zapardiel-Gonzalo J, White B, Singh D, Schulten V, Dillon M, Hinz D, Broide DH, Sette A, Peters B, Vijayanand P. PMID: 27271570; PMCID: PMC4936908.
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PubMed Mentions:
46 Fields:
Translation:
HumansCells
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Lack of allergy to timothy grass pollen is not a passive phenomenon but associated with the allergen-specific modulation of immune reactivity. Clin Exp Allergy. 2016 05; 46(5):705-19.
Hinz D, Seumois G, Gholami AM, Greenbaum JA, Lane J, White B, Broide DH, Schulten V, Sidney J, Bakhru P, Oseroff C, Wambre E, James EA, Kwok WW, Peters B, Vijayanand P, Sette A. PMID: 26662458; PMCID: PMC4846575.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma. J Allergy Clin Immunol. 2016 08; 138(2):596-599.e4.
Miller M, Esnault S, Kurten RC, Kelly EA, Beppu A, Das S, Rosenthal P, Ramsdell J, Croft M, Zuraw B, Jarjour N, Hamid Q, Broide DH. PMID: 27001159; PMCID: PMC4975994.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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TGF-β1-induced PAI-1 contributes to a profibrotic network in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2016 09; 138(3):791-800.e4.
Rawson R, Yang T, Newbury RO, Aquino M, Doshi A, Bell B, Broide DH, Dohil R, Kurten R, Aceves SS. PMID: 27212082; PMCID: PMC5014565.
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PubMed Mentions:
38 Fields:
Translation:
HumansCells
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Regulatory B cells and T follicular helper cells are reduced in allergic rhinitis. J Allergy Clin Immunol. 2016 10; 138(4):1192-1195.e5.
Kim AS, Doherty TA, Karta MR, Das S, Baum R, Rosenthal P, Beppu A, Miller M, Kurten R, Broide DH. PMID: 27142393; PMCID: PMC5053844.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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miR-23∼27∼24 clusters control effector T cell differentiation and function. J Exp Med. 2016 Feb 08; 213(2):235-49.
Cho S, Wu CJ, Yasuda T, Cruz LO, Khan AA, Lin LL, Nguyen DT, Miller M, Lee HM, Kuo ML, Broide DH, Rajewsky K, Rudensky AY, Lu LF. PMID: 26834155; PMCID: PMC4749926.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Insights into Group 2 Innate Lymphoid Cells in Human Airway Disease. Curr Allergy Asthma Rep. 2016 Jan; 16(1):8.
Karta MR, Broide DH, Doherty TA. PMID: 26746844; PMCID: PMC5026503.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Prostaglandin I2 Signaling and Inhibition of Group 2 Innate Lymphoid Cell Responses. Am J Respir Crit Care Med. 2016 Jan 01; 193(1):31-42.
Zhou W, Toki S, Zhang J, Goleniewksa K, Newcomb DC, Cephus JY, Dulek DE, Bloodworth MH, Stier MT, Polosuhkin V, Gangula RD, Mallal SA, Broide DH, Peebles RS. PMID: 26378386; PMCID: PMC4731613.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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The TGFβ1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis. PLoS One. 2015; 10(12):e0144651.
Rawson R, Anilkumar A, Newbury RO, Bafna V, Aquino M, Palmquist J, Hoffman HM, Mueller JL, Dohil R, Broide DH, Aceves SS. PMID: 26656423; PMCID: PMC4678166.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Oct 15; 195(8):3546-56.
Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. PMID: 26355153; PMCID: PMC4811198.
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PubMed Mentions:
25 Fields:
Translation:
HumansAnimalsCells
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MMPs-2 and -14 Are Elevated in Eosinophilic Esophagitis and Reduced Following Topical Corticosteroid Therapy. J Pediatr Gastroenterol Nutr. 2015 Aug; 61(2):194-9.
Beppu L, Yang T, Luk M, Newbury RO, Palmquist J, Dohil R, Kurten RC, Broide DH, Aceves SS. PMID: 25539192; PMCID: PMC4478274.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Long-term assessment of esophageal remodeling in patients with pediatric eosinophilic esophagitis treated with topical corticosteroids. J Allergy Clin Immunol. 2016 Jan; 137(1):147-156.e8.
Rajan J, Newbury RO, Anilkumar A, Dohil R, Broide DH, Aceves SS. PMID: 26233926; PMCID: PMC4715736.
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PubMed Mentions:
42 Fields:
Translation:
Humans
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Group 2 innate lymphocytes (ILC2) are enriched in active eosinophilic esophagitis. J Allergy Clin Immunol. 2015 Sep; 136(3):792-794.e3.
Doherty TA, Baum R, Newbury RO, Yang T, Dohil R, Aquino M, Doshi A, Walford HH, Kurten RC, Broide DH, Aceves S. PMID: 26233928; PMCID: PMC4562810.
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PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33. J Allergy Clin Immunol. 2016 Jan; 137(1):278-288.e6.
Mehta AK, Duan W, Doerner AM, Traves SL, Broide DH, Proud D, Zuraw BL, Croft M. PMID: 26100084; PMCID: PMC4684822.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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Cyclic AMP concentrations in dendritic cells induce and regulate Th2 immunity and allergic asthma. Proc Natl Acad Sci U S A. 2015 Feb 03; 112(5):1529-34.
Lee J, Kim TH, Murray F, Li X, Choi SS, Broide DH, Corr M, Lee J, Webster NJ, Insel PA, Raz E. PMID: 25605931; PMCID: PMC4321256.
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PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Group 2 innate lymphoid cells: new players in human allergic diseases. J Investig Allergol Clin Immunol. 2015; 25(1):1-11; quiz 2p following 11.
Doherty TA, Broide DH. PMID: 25898689; PMCID: PMC4545833.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness. Clin Immunol. 2014 Nov; 155(1):126-135.
Walford HH, Lund SJ, Baum RE, White AA, Bergeron CM, Husseman J, Bethel KJ, Scott DR, Khorram N, Miller M, Broide DH, Doherty TA. PMID: 25236785; PMCID: PMC4254351.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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Association between specific timothy grass antigens and changes in TH1- and TH2-cell responses following specific immunotherapy. J Allergy Clin Immunol. 2014 Nov; 134(5):1076-83.
Schulten V, Tripple V, Sidney J, Greenbaum J, Frazier A, Alam R, Broide D, Peters B, Sette A. PMID: 25042980; PMCID: PMC4253970.
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Smad3-deficient mice have reduced esophageal fibrosis and angiogenesis in a model of egg-induced eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2014 Jul; 59(1):10-6.
Cho JY, Doshi A, Rosenthal P, Beppu A, Miller M, Aceves S, Broide D. PMID: 24590208; PMCID: PMC4148477.
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PubMed Mentions:
35 Fields:
Translation:
AnimalsCells
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Id2 and Id3 maintain the regulatory T cell pool to suppress inflammatory disease. Nat Immunol. 2014 Aug; 15(8):767-76.
Miyazaki M, Miyazaki K, Chen S, Itoi M, Miller M, Lu LF, Varki N, Chang AN, Broide DH, Murre C. PMID: 24973820; PMCID: PMC4365819.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites. Proc Natl Acad Sci U S A. 2014 Jun 03; 111(22):8173-8.
Nonaka M, Bao X, Matsumura F, Götze S, Kandasamy J, Kononov A, Broide DH, Nakayama J, Seeberger PH, Fukuda M. PMID: 24835176; PMCID: PMC4050563.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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TGF-β1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Nov; 134(5):1100-1107.e4.
Beppu LY, Anilkumar AA, Newbury RO, Dohil R, Broide DH, Aceves SS. PMID: 24835503; PMCID: PMC4231011.
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PubMed Mentions:
46 Fields:
Translation:
HumansCells
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ORMDL3 transgenic mice have increased airway remodeling and airway responsiveness characteristic of asthma. J Immunol. 2014 Apr 15; 192(8):3475-87.
Miller M, Rosenthal P, Beppu A, Mueller JL, Hoffman HM, Tam AB, Doherty TA, McGeough MD, Pena CA, Suzukawa M, Niwa M, Broide DH. PMID: 24623133; PMCID: PMC3981544.
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PubMed Mentions:
92 Fields:
Translation:
HumansAnimalsCells
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Allergen challenge in allergic rhinitis rapidly induces increased peripheral blood type 2 innate lymphoid cells that express CD84. J Allergy Clin Immunol. 2014 Apr; 133(4):1203-5.
Doherty TA, Scott D, Walford HH, Khorram N, Lund S, Baum R, Chang J, Rosenthal P, Beppu A, Miller M, Broide DH. PMID: 24582313; PMCID: PMC3972276.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. Int Immunopharmacol. 2014 Jan; 18(1):35-42.
Cho JY, Rosenthal P, Miller M, Pham A, Aceves S, Sakuda S, Broide DH. PMID: 24239745; PMCID: PMC3908829.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Prostaglandin D2 regulates human type 2 innate lymphoid cell chemotaxis. J Allergy Clin Immunol. 2014 Mar; 133(3):899-901.e3.
Chang JE, Doherty TA, Baum R, Broide D. PMID: 24210841; PMCID: PMC3943597.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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Human mesenchymal stem cells suppress the stretch-induced inflammatory miR-155 and cytokines in bronchial epithelial cells. PLoS One. 2013; 8(8):e71342.
Kuo YC, Li YS, Zhou J, Shih YR, Miller M, Broide D, Lee OK, Chien S. PMID: 23967196; PMCID: PMC3742760.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Lung type 2 innate lymphoid cells express cysteinyl leukotriene receptor 1, which regulates TH2 cytokine production. J Allergy Clin Immunol. 2013 Jul; 132(1):205-13.
Doherty TA, Khorram N, Lund S, Mehta AK, Croft M, Broide DH. PMID: 23688412; PMCID: PMC3704056.
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PubMed Mentions:
210 Fields:
Translation:
AnimalsCells
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Sialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in mice. J Immunol. 2013 Jun 15; 190(12):5939-48.
Suzukawa M, Miller M, Rosenthal P, Cho JY, Doherty TA, Varki A, Broide D. PMID: 23677475; PMCID: PMC3679360.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2013 Jun; 131(6):1576-82.
Otani IM, Anilkumar AA, Newbury RO, Bhagat M, Beppu LY, Dohil R, Broide DH, Aceves SS. PMID: 23623266; PMCID: PMC3699422.
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PubMed Mentions:
75 Fields:
Translation:
HumansCells
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Lung-resident tissue macrophages generate Foxp3+ regulatory T cells and promote airway tolerance. J Exp Med. 2013 Apr 08; 210(4):775-88.
Soroosh P, Doherty TA, Duan W, Mehta AK, Choi H, Adams YF, Mikulski Z, Khorram N, Rosenthal P, Broide DH, Croft M. PMID: 23547101; PMCID: PMC3620360.
View in:
PubMed Mentions:
184 Fields:
Translation:
AnimalsCells
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Hypoxia potentiates allergen induction of HIF-1α, chemokines, airway inflammation, TGF-β1, and airway remodeling in a mouse model. Clin Immunol. 2013 Apr; 147(1):27-37.
Baek KJ, Cho JY, Rosenthal P, Alexander LEC, Nizet V, Broide DH. PMID: 23499929; PMCID: PMC3812068.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3459-64.
Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Ferreira-Briza F, Grey HM, Sette A, Peters B. PMID: 23401558; PMCID: PMC3587276.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansAnimalsCells
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A strategy to determine HLA class II restriction broadly covering the DR, DP, and DQ allelic variants most commonly expressed in the general population. Immunogenetics. 2013 May; 65(5):357-70.
McKinney DM, Southwood S, Hinz D, Oseroff C, Arlehamn CS, Schulten V, Taplitz R, Broide D, Hanekom WA, Scriba TJ, Wood R, Alam R, Peters B, Sidney J, Sette A. PMID: 23392739; PMCID: PMC3633633.
View in:
PubMed Mentions:
57 Fields:
Translation:
HumansCells
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Myeloid cell HIF-1α regulates asthma airway resistance and eosinophil function. J Mol Med (Berl). 2013 May; 91(5):637-44.
Crotty Alexander LE, Akong-Moore K, Feldstein S, Johansson P, Nguyen A, McEachern EK, Nicatia S, Cowburn AS, Olson J, Cho JY, Isaacs H, Johnson RS, Broide DH, Nizet V. PMID: 23250618; PMCID: PMC3646920.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Strategies to query and display allergy-derived epitope data from the immune epitope database. Int Arch Allergy Immunol. 2013; 160(4):334-45.
Vaughan K, Peters B, Larche M, Pomes A, Broide D, Sette A. PMID: 23172234; PMCID: PMC3629817.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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The identification of potentially pathogenic and therapeutic epitopes from common human allergens. Ann Allergy Asthma Immunol. 2013 Jan; 110(1):7-10.
Schulten V, Oseroff C, Alam R, Broide D, Vijayanand P, Peters B, Sette A. PMID: 23244651; PMCID: PMC3547526.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6. Proc Natl Acad Sci U S A. 2012 Oct 09; 109(41):16648-53.
Miller M, Tam AB, Cho JY, Doherty TA, Pham A, Khorram N, Rosenthal P, Mueller JL, Hoffman HM, Suzukawa M, Niwa M, Broide DH. PMID: 23011799; PMCID: PMC3478632.
View in:
PubMed Mentions:
104 Fields:
Translation:
HumansAnimalsCells
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Epithelial cell-derived IL-25, but not Th17 cell-derived IL-17 or IL-17F, is crucial for murine asthma. J Immunol. 2012 Oct 01; 189(7):3641-52.
Suzukawa M, Morita H, Nambu A, Arae K, Shimura E, Shibui A, Yamaguchi S, Suzukawa K, Nakanishi W, Oboki K, Kajiwara N, Ohno T, Ishii A, Körner H, Cua DJ, Suto H, Yoshimoto T, Iwakura Y, Yamasoba T, Ohta K, Sudo K, Saito H, Okumura K, Broide DH, Matsumoto K, Nakae S. PMID: 22942422; PMCID: PMC3812057.
View in:
PubMed Mentions:
44 Fields:
Translation:
AnimalsCells
-
STAT6 regulates natural helper cell proliferation during lung inflammation initiated by Alternaria. Am J Physiol Lung Cell Mol Physiol. 2012 Oct 01; 303(7):L577-88.
Doherty TA, Khorram N, Chang JE, Kim HK, Rosenthal P, Croft M, Broide DH. PMID: 22865552; PMCID: PMC3469584.
View in:
PubMed Mentions:
93 Fields:
Translation:
HumansAnimalsCells
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T cell responses to known allergen proteins are differently polarized and account for a variable fraction of total response to allergen extracts. J Immunol. 2012 Aug 15; 189(4):1800-11.
Oseroff C, Sidney J, Vita R, Tripple V, McKinney DM, Southwood S, Brodie TM, Sallusto F, Grey H, Alam R, Broide D, Greenbaum JA, Kolla R, Peters B, Sette A. PMID: 22786768; PMCID: PMC3411923.
View in:
PubMed Mentions:
41 Fields:
Translation:
HumansCells
-
Analysis of T cell responses to the major allergens from German cockroach: epitope specificity and relationship to IgE production. J Immunol. 2012 Jul 15; 189(2):679-88.
Oseroff C, Sidney J, Tripple V, Grey H, Wood R, Broide DH, Greenbaum J, Kolla R, Peters B, Pomés A, Sette A. PMID: 22706084; PMCID: PMC3392449.
View in:
PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Alternaria induces STAT6-dependent acute airway eosinophilia and epithelial FIZZ1 expression that promotes airway fibrosis and epithelial thickness. J Immunol. 2012 Mar 15; 188(6):2622-9.
Doherty TA, Khorram N, Sugimoto K, Sheppard D, Rosenthal P, Cho JY, Pham A, Miller M, Croft M, Broide DH. PMID: 22327070; PMCID: PMC3294141.
View in:
PubMed Mentions:
58 Fields:
Translation:
Animals
-
Histamine-releasing factor has a proinflammatory role in mouse models of asthma and allergy. J Clin Invest. 2012 Jan; 122(1):218-28.
Kashiwakura JC, Ando T, Matsumoto K, Kimura M, Kitaura J, Matho MH, Zajonc DM, Ozeki T, Ra C, MacDonald SM, Siraganian RP, Broide DH, Kawakami Y, Kawakami T. PMID: 22133880; PMCID: PMC3248297.
View in:
PubMed Mentions:
40 Fields:
Translation:
AnimalsCells
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Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2011 Oct; 53(4):409-16.
Rubinstein E, Cho JY, Rosenthal P, Chao J, Miller M, Pham A, Aceves SS, Varki A, Broide DH. PMID: 21970996; PMCID: PMC3980963.
View in:
PubMed Mentions:
57 Fields:
Translation:
AnimalsCells
-
The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med. 2011 May; 17(5):596-603.
Doherty TA, Soroosh P, Khorram N, Fukuyama S, Rosenthal P, Cho JY, Norris PS, Choi H, Scheu S, Pfeffer K, Zuraw BL, Ware CF, Broide DH, Croft M. PMID: 21499267; PMCID: PMC3097134.
View in:
PubMed Mentions:
86 Fields:
Translation:
HumansAnimalsCells
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Chronic OVA allergen challenged TNF p55/p75 receptor deficient mice have reduced airway remodeling. Int Immunopharmacol. 2011 Aug; 11(8):1038-44.
Cho JY, Pham A, Rosenthal P, Miller M, Doherty T, Broide DH. PMID: 21382533; PMCID: PMC3121895.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Advances in mechanisms of asthma, allergy, and immunology in 2010. J Allergy Clin Immunol. 2011 Mar; 127(3):689-95.
Broide DH, Finkelman F, Bochner BS, Rothenberg ME. PMID: 21377038.
View in:
PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Towards defining molecular determinants recognized by adaptive immunity in allergic disease: an inventory of the available data. J Allergy (Cairo). 2010; 2010:628026.
Vaughan K, Greenbaum J, Kim Y, Vita R, Chung J, Peters B, Broide D, Goodman R, Grey H, Sette A. PMID: 21403821; PMCID: PMC3042621.
View in:
PubMed Mentions:
8
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TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media. BMC Immunol. 2011 Jan 26; 12:12.
Ebmeyer J, Leichtle A, Hernandez M, Ebmeyer U, Husseman J, Pak K, Sudhoff H, Broide D, Wasserman SI, Ryan AF. PMID: 21269505; PMCID: PMC3040143.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimals
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Allergen-induced coexpression of bFGF and TGF-β1 by macrophages in a mouse model of airway remodeling: bFGF induces macrophage TGF-β1 expression in vitro. Int Arch Allergy Immunol. 2011; 155(1):12-22.
Yum HY, Cho JY, Miller M, Broide DH. PMID: 21109744; PMCID: PMC2997445.
View in:
PubMed Mentions:
8 Fields:
Translation:
AnimalsCellsPHPublic Health
-
Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-β1, and increase esophageal smooth muscle contraction. J Allergy Clin Immunol. 2010 Dec; 126(6):1198-204.e4.
Aceves SS, Chen D, Newbury RO, Dohil R, Bastian JF, Broide DH. PMID: 21047675.
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PubMed Mentions:
128 Fields:
Translation:
HumansCells
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Chronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13. Respir Res. 2010 Nov 01; 11:154.
Cho JY, Song DJ, Pham A, Rosenthal P, Miller M, Dayan S, Doherty TA, Varki A, Broide DH. PMID: 21040544; PMCID: PMC2988013.
View in:
PubMed Mentions:
29 Fields:
Translation:
AnimalsCells
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Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years. Chest. 2011 Jun; 139(6):1380-1387.
Miller M, Cho JY, Pham A, Friedman PJ, Ramsdell J, Broide DH. PMID: 20966041; PMCID: PMC3109645.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
-
Adiponectin-deficient mice are protected against tobacco-induced inflammation and increased emphysema. Am J Physiol Lung Cell Mol Physiol. 2010 Dec; 299(6):L834-42.
Miller M, Pham A, Cho JY, Rosenthal P, Broide DH. PMID: 20935231; PMCID: PMC3006270.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
-
Allergic rhinitis: Pathophysiology. Allergy Asthma Proc. 2010 Sep-Oct; 31(5):370-4.
Broide DH. PMID: 20929602.
View in:
PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Molecular determinants of T cell epitope recognition to the common Timothy grass allergen. J Immunol. 2010 Jul 15; 185(2):943-55.
Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A. PMID: 20554959; PMCID: PMC3310373.
View in:
PubMed Mentions:
104 Fields:
Translation:
HumansAnimalsCells
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Chronic allergen challenge induces bronchial mast cell accumulation in BALB/c but not C57BL/6 mice and is independent of IL-9. Immunogenetics. 2010 Aug; 62(8):499-506.
Pae S, Cho JY, Dayan S, Miller M, Pemberton AD, Broide DH. PMID: 20480160; PMCID: PMC2910299.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Inactivation of I kappaB-kinase-beta dependent genes in airway epithelium reduces tobacco smoke induced acute airway inflammation. Int Immunopharmacol. 2010 Aug; 10(8):906-12.
Lee SY, Miller M, Cho JY, Song DJ, Karin M, Broide DH. PMID: 20494824; PMCID: PMC2908188.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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Tobacco smoke promotes lung tumorigenesis by triggering IKKbeta- and JNK1-dependent inflammation. Cancer Cell. 2010 Jan 19; 17(1):89-97.
Takahashi H, Ogata H, Nishigaki R, Broide DH, Karin M. PMID: 20129250; PMCID: PMC2818776.
View in:
PubMed Mentions:
239 Fields:
Translation:
AnimalsPHPublic Health
-
Reconstitution of the mast cell population in W/Wv mice. Otol Neurotol. 2010 Jan; 31(1):42-7.
Ebmeyer J, Ebmeyer U, Pak K, Sudhoff H, Broide D, Ryan AF, Wasserman S. PMID: 19752767; PMCID: PMC2796298.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Innate immunity. J Allergy Clin Immunol. 2010 Feb; 125(2 Suppl 2):S24-32.
Turvey SE, Broide DH. PMID: 19932920; PMCID: PMC2832725.
-
Toll-like receptor-9 agonist inhibits airway inflammation, remodeling and hyperreactivity in mice exposed to chronic environmental tobacco smoke and allergen. Int Arch Allergy Immunol. 2010; 151(4):285-96.
Song DJ, Min MG, Miller M, Cho JY, Yum HY, Broide DH. PMID: 19851071; PMCID: PMC2853586.
View in:
PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Resolution of remodeling in eosinophilic esophagitis correlates with epithelial response to topical corticosteroids. Allergy. 2010 Jan; 65(1):109-16.
Aceves SS, Newbury RO, Chen D, Mueller J, Dohil R, Hoffman H, Bastian JF, Broide DH. PMID: 19796194; PMCID: PMC2807896.
View in:
PubMed Mentions:
121 Fields:
Translation:
HumansCells
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Anti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodeling. J Immunol. 2009 Oct 15; 183(8):5333-41.
Song DJ, Cho JY, Lee SY, Miller M, Rosenthal P, Soroosh P, Croft M, Zhang M, Varki A, Broide DH. PMID: 19783675; PMCID: PMC2788790.
View in:
PubMed Mentions:
58 Fields:
Translation:
AnimalsCells
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Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen. Am J Physiol Lung Cell Mol Physiol. 2009 Aug; 297(2):L380-7.
Song DJ, Min MG, Miller M, Cho JY, Broide DH. PMID: 19525386; PMCID: PMC2742786.
View in:
PubMed Mentions:
4 Fields:
Translation:
AnimalsCellsPHPublic Health
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Potent inhibitors of pro-inflammatory cytokine production produced by a marine-derived bacterium. J Med Chem. 2009 Apr 23; 52(8):2317-27.
Strangman WK, Kwon HC, Broide D, Jensen PR, Fenical W. PMID: 19323483; PMCID: PMC2735501.
View in:
PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
-
Advances in mechanisms of asthma, allergy, and immunology in 2008. J Allergy Clin Immunol. 2009 Mar; 123(3):569-74.
Boyce JA, Broide D, Matsumoto K, Bochner BS. PMID: 19281904; PMCID: PMC2671063.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Anti-Siglec-F antibody inhibits oral egg allergen induced intestinal eosinophilic inflammation in a mouse model. Clin Immunol. 2009 Apr; 131(1):157-69.
Song DJ, Cho JY, Miller M, Strangman W, Zhang M, Varki A, Broide DH. PMID: 19135419; PMCID: PMC2683248.
View in:
PubMed Mentions:
39 Fields:
Translation:
AnimalsCells
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Immunomodulation of allergic disease. Annu Rev Med. 2009; 60:279-91.
Broide DH. PMID: 19630573; PMCID: PMC2779001.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease. J Immunol. 2009 Jan 01; 182(1):684-91.
Miller M, Cho JY, Pham A, Ramsdell J, Broide DH. PMID: 19109202.
View in:
PubMed Mentions:
75 Fields:
Translation:
HumansAnimalsCells
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Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis. 2008 Dec 15; 198(12):1862-9.
Hernandez M, Leichtle A, Pak K, Ebmeyer J, Euteneuer S, Obonyo M, Guiney DG, Webster NJ, Broide DH, Ryan AF, Wasserman SI. PMID: 18986247; PMCID: PMC3584630.
View in:
PubMed Mentions:
46 Fields:
Translation:
AnimalsCells
-
CD4+ cells are required for chronic eosinophilic lung inflammation but not airway remodeling. Am J Physiol Lung Cell Mol Physiol. 2009 Feb; 296(2):L229-35.
Doherty TA, Soroosh P, Broide DH, Croft M. PMID: 19060225; PMCID: PMC2643996.
View in:
PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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PI3K gamma-deficient mice have reduced levels of allergen-induced eosinophilic inflammation and airway remodeling. Am J Physiol Lung Cell Mol Physiol. 2009 Feb; 296(2):L210-9.
Lim DH, Cho JY, Song DJ, Lee SY, Miller M, Broide DH. PMID: 19028980; PMCID: PMC2643991.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
New perspectives on mechanisms underlying chronic allergic inflammation and asthma in 2007. J Allergy Clin Immunol. 2008 Sep; 122(3):475-80.
Broide D. PMID: 18694589.
View in:
PubMed Mentions:
8 Fields:
Translation:
HumansAnimalsCells
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Airway fibrosis and angiogenesis due to eosinophil trafficking in chronic asthma. Curr Mol Med. 2008 Aug; 8(5):350-8.
Aceves SS, Broide DH. PMID: 18691061.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
-
An antiinflammatory role for IKKbeta through the inhibition of "classical" macrophage activation. J Exp Med. 2008 Jun 09; 205(6):1269-76.
Fong CH, Bebien M, Didierlaurent A, Nebauer R, Hussell T, Broide D, Karin M, Lawrence T. PMID: 18490491; PMCID: PMC2413025.
View in:
PubMed Mentions:
91 Fields:
Translation:
HumansAnimalsCells
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Immunologic and inflammatory mechanisms that drive asthma progression to remodeling. J Allergy Clin Immunol. 2008 Mar; 121(3):560-70; quiz 571-2.
Broide DH. PMID: 18328887; PMCID: PMC2386668.
View in:
PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
-
Down-regulation of caveolin-1, an inhibitor of transforming growth factor-beta signaling, in acute allergen-induced airway remodeling. J Biol Chem. 2008 Feb 29; 283(9):5760-8.
Le Saux CJ, Teeters K, Miyasato SK, Hoffmann PR, Bollt O, Douet V, Shohet RV, Broide DH, Tam EK. PMID: 18056268.
View in:
PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
-
3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18619-24.
Hayashi T, Mo JH, Gong X, Rossetto C, Jang A, Beck L, Elliott GI, Kufareva I, Abagyan R, Broide DH, Lee J, Raz E. PMID: 18003900; PMCID: PMC2141826.
View in:
PubMed Mentions:
79 Fields:
Translation:
HumansAnimalsCells
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Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J Allergy Clin Immunol. 2007 Nov; 120(5):1118-25.
Miller M, Ramsdell J, Friedman PJ, Cho JY, Renvall M, Broide DH. PMID: 17983873.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansCells
-
Cytokines and growth factors in airway remodeling in asthma. Curr Opin Immunol. 2007 Dec; 19(6):676-80.
Doherty T, Broide D. PMID: 17720466.
View in:
PubMed Mentions:
89 Fields:
Translation:
HumansAnimalsCells
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The pathophysiology of allergic rhinoconjunctivitis. Allergy Asthma Proc. 2007 Jul-Aug; 28(4):398-403.
Broide DH. PMID: 17883906.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
Inhibition of allergen-induced airway remodeling in Smad 3-deficient mice. J Immunol. 2007 Jun 01; 178(11):7310-6.
Le AV, Cho JY, Miller M, McElwain S, Golgotiu K, Broide DH. PMID: 17513781.
View in:
PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
-
Coexposure to environmental tobacco smoke increases levels of allergen-induced airway remodeling in mice. J Immunol. 2007 Apr 15; 178(8):5321-8.
Min MG, Song DJ, Miller M, Cho JY, McElwain S, Ferguson P, Broide DH. PMID: 17404317.
View in:
PubMed Mentions:
16 Fields:
Translation:
AnimalsPHPublic Health
-
Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood. 2007 May 15; 109(10):4280-7.
Zhang M, Angata T, Cho JY, Miller M, Broide DH, Varki A. PMID: 17272508; PMCID: PMC1885492.
View in:
PubMed Mentions:
110 Fields:
Translation:
AnimalsCells
-
Esophageal remodeling in pediatric eosinophilic esophagitis. J Allergy Clin Immunol. 2007 Jan; 119(1):206-12.
Aceves SS, Newbury RO, Dohil R, Bastian JF, Broide DH. PMID: 17208603.
View in:
PubMed Mentions:
179 Fields:
Translation:
Humans
-
Immunotherapy with a ragweed-toll-like receptor 9 agonist vaccine for allergic rhinitis. N Engl J Med. 2006 Oct 05; 355(14):1445-55.
Creticos PS, Schroeder JT, Hamilton RG, Balcer-Whaley SL, Khattignavong AP, Lindblad R, Li H, Coffman R, Seyfert V, Eiden JJ, Broide D, Immune Tolerance Network Group. PMID: 17021320.
View in:
PubMed Mentions:
145 Fields:
Translation:
HumansAnimalsCTClinical Trials
-
Reduced peribronchial fibrosis in allergen-challenged MMP-9-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2006 Aug; 291(2):L265-71.
Lim DH, Cho JY, Miller M, McElwain K, McElwain S, Broide DH. PMID: 16825657.
View in:
PubMed Mentions:
43 Fields:
Translation:
HumansAnimals
-
Remodeling associated expression of matrix metalloproteinase 9 but not tissue inhibitor of metalloproteinase 1 in airway epithelium: modulation by immunostimulatory DNA. J Allergy Clin Immunol. 2006 Mar; 117(3):618-25.
Cho JY, Miller M, McElwain K, McElwain S, Shim JY, Raz E, Broide DH. PMID: 16522462.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Indoleamine-2,3-dioxygenase modulation of allergic immune responses. Curr Allergy Asthma Rep. 2006 Feb; 6(1):27-31.
Le AV, Broide DH. PMID: 16476191.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansAnimalsCells
-
Immunostimulatory DNA inhibits allergen-induced peribronchial angiogenesis in mice. J Allergy Clin Immunol. 2006 Mar; 117(3):597-603.
Lee SY, Cho JY, Miller M, McElwain K, McElwain S, Sriramarao P, Raz E, Broide DH. PMID: 16522459.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
-
Corticosteroids prevent myofibroblast accumulation and airway remodeling in mice. Am J Physiol Lung Cell Mol Physiol. 2006 Jan; 290(1):L162-9.
Miller M, Cho JY, McElwain K, McElwain S, Shim JY, Manni M, Baek JS, Broide DH. PMID: 16344333.
View in:
PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
-
Prospects for CpG based immunotherapy in asthma and allergy. Arb Paul Ehrlich Inst Bundesamt Sera Impfstoffe Frankf A M. 2006; (95):217-20; discussion 220-2.
Broide DH. PMID: 17393743.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
-
Allergen-induced peribronchial fibrosis and mucus production mediated by IkappaB kinase beta-dependent genes in airway epithelium. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17723-8.
Broide DH, Lawrence T, Doherty T, Cho JY, Miller M, McElwain K, McElwain S, Karin M. PMID: 16317067; PMCID: PMC1308936.
View in:
PubMed Mentions:
67 Fields:
Translation:
AnimalsCells
-
Combination of corticosteroid therapy and allergen avoidance reverses allergen-induced airway remodeling in mice. J Allergy Clin Immunol. 2005 Nov; 116(5):1116-22.
Cho JY, Miller M, McElwain K, McElwain S, Broide DH. PMID: 16275385.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Role of mast cells in otitis media. J Allergy Clin Immunol. 2005 Nov; 116(5):1129-35.
Ebmeyer J, Furukawa M, Pak K, Ebmeyer U, Sudhoff H, Broide D, Ryan AF, Wasserman S. PMID: 16275387.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
-
Immunostimulatory sequences of DNA and conjugates in the treatment of allergic rhinitis. Curr Allergy Asthma Rep. 2005 May; 5(3):182-5.
Broide DH. PMID: 15842954.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
-
Induction and inhibition of the Th2 phenotype spread: implications for childhood asthma. J Immunol. 2005 May 01; 174(9):5864-73.
Hayashi T, Gong X, Rossetto C, Shen C, Takabayashi K, Redecke V, Spiegelberg H, Broide D, Raz E. PMID: 15843591.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
-
DNA vaccines: an evolving approach to the treatment of allergic disorders. Allergy Asthma Proc. 2005 May-Jun; 26(3):195-8.
Broide DH. PMID: 16119033.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
-
Immunostimulatory DNA reverses established allergen-induced airway remodeling. J Immunol. 2004 Dec 15; 173(12):7556-64.
Youn CJ, Miller M, Baek KJ, Han JW, Nayar J, Lee SY, McElwain K, McElwain S, Raz E, Broide DH. PMID: 15585883.
View in:
PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
-
Immunomodulation and reversal of airway remodeling in asthma. Curr Opin Allergy Clin Immunol. 2004 Dec; 4(6):529-32.
Broide D. PMID: 15640694.
View in:
PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest. 2004 Aug; 114(3):427-37.
Binder CJ, Hartvigsen K, Chang MK, Miller M, Broide D, Palinski W, Curtiss LK, Corr M, Witztum JL. PMID: 15286809; PMCID: PMC484976.
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PubMed Mentions:
173 Fields:
Translation:
AnimalsCells
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Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J Clin Invest. 2004 Jul; 114(2):270-9.
Hayashi T, Beck L, Rossetto C, Gong X, Takikawa O, Takabayashi K, Broide DH, Carson DA, Raz E. PMID: 15254594; PMCID: PMC449749.
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PubMed Mentions:
118 Fields:
Translation:
AnimalsCells
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Cutting edge: activation of Toll-like receptor 2 induces a Th2 immune response and promotes experimental asthma. J Immunol. 2004 Mar 01; 172(5):2739-43.
Redecke V, Häcker H, Datta SK, Fermin A, Pitha PM, Broide DH, Raz E. PMID: 14978071.
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PubMed Mentions:
150 Fields:
Translation:
AnimalsCells
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Inhibition of airway remodeling in IL-5-deficient mice. J Clin Invest. 2004 Feb; 113(4):551-60.
Cho JY, Miller M, Baek KJ, Han JW, Nayar J, Lee SY, McElwain K, McElwain S, Friedman S, Broide DH. PMID: 14966564; PMCID: PMC338264.
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PubMed Mentions:
158 Fields:
Translation:
HumansAnimalsCells
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Immunostimulatory DNA inhibits transforming growth factor-beta expression and airway remodeling. Am J Respir Cell Mol Biol. 2004 May; 30(5):651-61.
Cho JY, Miller M, Baek KJ, Han JW, Nayar J, Rodriguez M, Lee SY, McElwain K, McElwain S, Raz E, Broide DH. PMID: 14617508.
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PubMed Mentions:
27 Fields:
Translation:
HumansAnimalsCells
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Accumulation of peribronchial mast cells in a mouse model of ovalbumin allergen induced chronic airway inflammation: modulation by immunostimulatory DNA sequences. J Immunol. 2003 Nov 01; 171(9):4860-7.
Ikeda RK, Miller M, Nayar J, Walker L, Cho JY, McElwain K, McElwain S, Raz E, Broide DH. PMID: 14568966.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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New targets for allergic rhinitis--a disease of civilization. Nat Rev Drug Discov. 2003 Nov; 2(11):902-14.
Holgate ST, Broide D. PMID: 14668811.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Resolution of airway inflammation following ovalbumin inhalation: comparison of ISS DNA and corticosteroids. Am J Respir Cell Mol Biol. 2003 Jun; 28(6):655-63.
Ikeda RK, Nayar J, Cho JY, Miller M, Rodriguez M, Raz E, Broide DH. PMID: 12760963.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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A murine model to study leukocyte rolling and intravascular trafficking in lung microvessels. Am J Pathol. 2003 Jun; 162(6):2019-28.
Sikora L, Johansson AC, Rao SP, Hughes GK, Broide DH, Sriramarao P. PMID: 12759257; PMCID: PMC1868130.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. Hum Genet. 2003 Feb; 112(2):209-16.
Hoffman HM, Gregory SG, Mueller JL, Tresierras M, Broide DH, Wanderer AA, Kolodner RD. PMID: 12522564.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Constitutive overexpression of IL-5 induces extramedullary hematopoiesis in the spleen. Blood. 2003 Feb 01; 101(3):863-8.
Khaldoyanidi S, Sikora L, Broide DH, Rothenberg ME, Sriramarao P. PMID: 12393708.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Plasmid DNA encoding the respiratory syncytial virus G protein protects against RSV-induced airway hyperresponsiveness. Vaccine. 2002 Jul 26; 20(23-24):3023-33.
Miller M, Cho JY, Baek KJ, Castaneda D, Nayar J, Rodriguez M, Roman M, Raz E, Broide DH. PMID: 12126916.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Fast flowing eosinophils: signals for stopping and stepping out of blood vessels. Am J Respir Cell Mol Biol. 2002 Jun; 26(6):637-40.
Broide D. PMID: 12034560.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Core 2 oligosaccharides mediate eosinophil and neutrophil peritoneal but not lung recruitment. Am J Physiol Lung Cell Mol Physiol. 2002 Feb; 282(2):L259-66.
Broide DH, Miller M, Castaneda D, Nayar J, Cho JY, Roman M, Ellies LG, Sriramarao P. PMID: 11792630.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Immunologic treatment of allergic diseases. Curr Opin Allergy Clin Immunol. 2001 Dec; 1(6):541-3.
Broide D, Malling HJ. PMID: 11964738.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001 Nov; 29(3):301-5.
Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. PMID: 11687797; PMCID: PMC4322000.
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PubMed Mentions:
598 Fields:
Translation:
HumansCells
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Immunostimulatory DNA sequences inhibit respiratory syncytial viral load, airway inflammation, and mucus secretion. J Allergy Clin Immunol. 2001 Nov; 108(5):697-702.
Cho JY, Miller M, Baek KJ, Castaneda D, Nayar J, Roman M, Raz E, Broide DH. PMID: 11692091.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Immunostimulatory DNA mediates inhibition of eosinophilic inflammation and airway hyperreactivity independent of natural killer cells in vivo. J Allergy Clin Immunol. 2001 Nov; 108(5):759-63.
Broide DH, Stachnick G, Castaneda D, Nayar J, Miller M, Cho J, Rodriquez M, Roman M, Raz E. PMID: 11692101.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Familial cold autoinflammatory syndrome: phenotype and genotype of an autosomal dominant periodic fever. J Allergy Clin Immunol. 2001 Oct; 108(4):615-20.
Hoffman HM, Wanderer AA, Broide DH. PMID: 11590390; PMCID: PMC4321996.
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PubMed Mentions:
95 Fields:
Translation:
HumansCells
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Eosinophil tissue recruitment to sites of allergic inflammation in the lung is platelet endothelial cell adhesion molecule independent. J Immunol. 2001 Aug 15; 167(4):2292-7.
Miller M, Sung KL, Muller WA, Cho JY, Roman M, Castaneda D, Nayar J, Condon T, Kim J, Sriramarao P, Broide DH. PMID: 11490017.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Molecular and cellular mechanisms of allergic disease. J Allergy Clin Immunol. 2001 Aug; 108(2 Suppl):S65-71.
Broide DH. PMID: 11498675.
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PubMed Mentions:
54 Fields:
Translation:
HumansCells
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Systemic administration of immunostimulatory DNA sequences mediates reversible inhibition of Th2 responses in a mouse model of asthma. J Clin Immunol. 2001 May; 21(3):175-82.
Broide DH, Stachnick G, Castaneda D, Nayar J, Miller M, Cho JY, Roman M, Zubeldia J, Hayashi T, Raz E, Hyashi T. PMID: 11403224.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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Regulated production of the T helper 2-type T-cell chemoattractant TARC by human bronchial epithelial cells in vitro and in human lung xenografts. Am J Respir Cell Mol Biol. 2001 Apr; 24(4):382-9.
Berin MC, Eckmann L, Broide DH, Kagnoff MF. PMID: 11306430.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Inhibition of eosinophilic inflammation in allergen-challenged TNF receptor p55/p75--and TNF receptor p55-deficient mice. Am J Respir Cell Mol Biol. 2001 Mar; 24(3):304-11.
Broide DH, Stachnick G, Castaneda D, Nayar J, Sriramarao P. PMID: 11245629.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Eosinophil trafficking to sites of allergic inflammation. Immunol Rev. 2001 Feb; 179:163-72.
Broide D, Sriramarao P. PMID: 11292020.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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DNA-based immunotherapeutics for the treatment of allergic disease. Immunol Rev. 2001 Feb; 179:102-18.
Horner AA, Van Uden JH, Zubeldia JM, Broide D, Raz E. PMID: 11292014.
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PubMed Mentions:
13 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Eotaxin induces a sustained reduction in the functional adhesive state of very late antigen 4 for the connecting segment 1 region of fibronectin. J Allergy Clin Immunol. 2000 Nov; 106(5):933-40.
Sung KP, Yang L, Kim J, Ko D, Stachnick G, Castaneda D, Nayar J, Broide DH. PMID: 11080717.
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PubMed Mentions:
4 Fields:
Translation:
HumansCells
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Identification of a locus on chromosome 1q44 for familial cold urticaria. Am J Hum Genet. 2000 May; 66(5):1693-8.
Hoffman HM, Wright FA, Broide DH, Wanderer AA, Kolodner RD. PMID: 10741953; PMCID: PMC1378006.
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PubMed Mentions:
30 Fields:
Translation:
HumansCells
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VCAM-1 is more effective than MAdCAM-1 in supporting eosinophil rolling under conditions of shear flow. Blood. 2000 Jan 15; 95(2):592-601.
Sriramarao P, DiScipio RG, Cobb RR, Cybulsky M, Stachnick G, Castaneda D, Elices M, Broide DH. PMID: 10627468.
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PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Modulation of asthmatic response by immunostimulatory DNA sequences. Springer Semin Immunopathol. 2000; 22(1-2):117-24.
Broide D, Cho JY, Miller M, Nayar J, Stachnick G, Castaneda D, Roman M, Raz E. PMID: 10944806.
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PubMed Mentions: Fields:
Translation:
HumansCellsPHPublic Health
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Genetic immunization for allergy immunotherapy. Methods Mol Med. 2000; 29:451-72.
Roman M, Tighe H, Spiegelberg HL, Broide D, Raz E. PMID: 21374341.
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PubMed Mentions: Fields:
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Inhibition of eosinophilic inflammation in allergen-challenged, IL-1 receptor type 1-deficient mice is associated with reduced eosinophil rolling and adhesion on vascular endothelium. Blood. 2000 Jan 01; 95(1):263-9.
Broide DH, Campbell K, Gifford T, Sriramarao P. PMID: 10607711.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Genes that regulate eosinophilic inflammation. Am J Hum Genet. 1999 Aug; 65(2):302-7.
Broide DH, Hoffman H, Sriramarao P. PMID: 10417272; PMCID: PMC1377928.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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DNA-Based immunization for asthma. Int Arch Allergy Immunol. 1999 Feb-Apr; 118(2-4):453-6.
Broide D, Raz E. PMID: 10224473.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCellsPHPublic Health
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A comparison of C3a and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo. J Immunol. 1999 Jan 15; 162(2):1127-36.
DiScipio RG, Daffern PJ, Jagels MA, Broide DH, Sriramarao P. PMID: 9916743.
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PubMed Mentions:
42 Fields:
Translation:
HumansAnimalsCells
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Inhibition of allergic inflammation in the lung by plasmid DNA allergen immunization. Pediatr Pulmonol Suppl. 1999; 18:118-21.
Spiegelberg HL, Broide D, Tighe H, Roman M, Raz E. PMID: 10093118.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Immunostimulatory DNA sequences inhibit IL-5, eosinophilic inflammation, and airway hyperresponsiveness in mice. J Immunol. 1998 Dec 15; 161(12):7054-62.
Broide D, Schwarze J, Tighe H, Gifford T, Nguyen MD, Malek S, Van Uden J, Martin-Orozco E, Gelfand EW, Raz E. PMID: 9862743.
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PubMed Mentions:
66 Fields:
Translation:
AnimalsCells
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Immunostimulatory DNA is a potent mucosal adjuvant. Cell Immunol. 1998 Nov 25; 190(1):77-82.
Horner AA, Ronaghy A, Cheng PM, Nguyen MD, Cho HJ, Broide D, Raz E. PMID: 9826449.
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PubMed Mentions:
18 Fields:
Translation:
AnimalsCells
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DNA immunotherapeutics: new potential treatment modalities for allergic disease. Int Arch Allergy Immunol. 1998 Jul; 116(3):177-87.
Goodman JS, Van Uden JH, Kobayashi H, Broide D, Raz E. PMID: 9693265.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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Inhibition of eosinophil rolling and recruitment in P-selectin- and intracellular adhesion molecule-1-deficient mice. Blood. 1998 Apr 15; 91(8):2847-56.
Broide DH, Humber D, Sullivan S, Sriramarao P. PMID: 9531595.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice. Am J Respir Cell Mol Biol. 1998 Feb; 18(2):218-25.
Broide DH, Sullivan S, Gifford T, Sriramarao P. PMID: 9476909.
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PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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Inhibition of IgE formation and allergic inflammation by allergen gene immunization and by CpG motif immunostimulatory oligodeoxynucleotides. Allergy. 1998; 53(45 Suppl):93-7.
Spiegelberg HL, Tighe H, Roman M, Broide D, Raz E. PMID: 9788716.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCellsPHPublic Health
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Granulocyte-macrophage colony-stimulating factor regulates the functional adhesive state of very late antigen-4 expressed by eosinophils. J Immunol. 1997 Jan 15; 158(2):919-27.
Sung KL, Li Y, Elices M, Gang J, Sriramarao P, Broide DH. PMID: 8993012.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Gene immunization for allergic disorders. Springer Semin Immunopathol. 1997; 19(2):223-32.
Roman M, Spiegelberg HL, Broide D, Raz E. PMID: 9406348.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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E-selectin preferentially supports neutrophil but not eosinophil rolling under conditions of flow in vitro and in vivo. J Immunol. 1996 Nov 15; 157(10):4672-80.
Sriramarao P, Norton CR, Borgstrom P, DiScipio RG, Wolitzky BA, Broide DH. PMID: 8906848.
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PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCells
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Differential regulation of eosinophil adhesion under conditions of flow in vivo. Ann N Y Acad Sci. 1996 Oct 31; 796:218-25.
Sriramarao P, Broide DH. PMID: 8906229.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Lidocaine in bronchoalveolar lavage fluid (BALF) is an inhibitor of eosinophil-active cytokines. Clin Exp Immunol. 1996 May; 104(2):325-31.
Ohnishi T, Kita H, Mayeno AN, Okada S, Sur S, Broide DH, Gleich GJ. PMID: 8625528; PMCID: PMC2200428.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Compartmentalization of eosinophil granulocyte-macrophage colony-stimulating factor expression in patients with asthma. J Allergy Clin Immunol. 1996 Apr; 97(4):966-76.
Sullivan S, Broide DH. PMID: 8655893.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Mouse bone marrow-derived mast cells roll on P-selectin under conditions of flow in vivo. Lab Invest. 1996 Mar; 74(3):634-43.
Sriramarao P, Anderson W, Wolitzky BA, Broide DH. PMID: 8600314.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Mast cell TNF mRNA expression in nasal mucosa demonstrated by in situ hybridization: a comparison of mast cell detection methods. J Immunol Methods. 1996 Feb 05; 189(2):145-55.
Anderson WH, Davidson TM, Broide DH. PMID: 8613667.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Differential expression of vascular cell adhesion molecule mRNA and protein in nasal mucosa in response to IL-1 or tumor necrosis factor. J Allergy Clin Immunol. 1996 Feb; 97(2):662-71.
Weinberger MS, Davidson TM, Broide DH. PMID: 8621852.
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PubMed Mentions: Fields:
Translation:
HumansCells
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Eosinophilic inflammation is associated with elevation of interleukin-5 in the airways of patients with spontaneous symptomatic asthma. J Allergy Clin Immunol. 1995 Nov; 96(5 Pt 1):661-8.
Sur S, Gleich GJ, Swanson MC, Bartemes KR, Broide DH. PMID: 7499683.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Alpha 4 integrin-induced cytokine production and eosinophil function. Springer Semin Immunopathol. 1995; 16(4):405-15.
Broide DH. PMID: 7570291.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCells
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Environmental and bronchoalveolar lavage Dermatophagoides pteronyssinus antigen levels in atopic asthmatics. Am J Respir Crit Care Med. 1995 Jan; 151(1):71-4.
Ferguson P, Broide DH. PMID: 7812575.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsPHPublic Health
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Clinical studies with cetirizine in allergic rhinitis and chronic urticaria. Allergy. 1995; 50(24 Suppl):31-5.
Broide D. PMID: 7645679.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo. J Immunol. 1994 Nov 01; 153(9):4238-46.
Sriramarao P, von Andrian UH, Butcher EC, Bourdon MA, Broide DH. PMID: 7523519.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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Eosinophil peroxidase differs from neutrophil myeloperoxidase in its ability to bind antineutrophil cytoplasmic antibodies reactive with myeloperoxidase. Int Arch Allergy Immunol. 1994 Oct; 105(2):150-4.
Sullivan S, Salapow MA, Breen R, Broide DH. PMID: 7920015.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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Eosinophils express interleukin 5 and granulocyte macrophage-colony-stimulating factor mRNA at sites of allergic inflammation in asthmatics. J Clin Invest. 1992 Oct; 90(4):1414-24.
Broide DH, Paine MM, Firestein GS. PMID: 1401075; PMCID: PMC443187.
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PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Cytokines in symptomatic asthma airways. J Allergy Clin Immunol. 1992 May; 89(5):958-67.
Broide DH, Lotz M, Cuomo AJ, Coburn DA, Federman EC, Wasserman SI. PMID: 1374772.
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PubMed Mentions:
156 Fields:
Translation:
HumansCells
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Cetirizine therapy for seasonal allergic rhinitis: alternative dosage schedules. Clin Ther. 1991 Nov-Dec; 13(6):707-13.
Wasserman SI, Broide DH, Marquardt DL. PMID: 1686422.
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PubMed Mentions:
1 Fields:
Translation:
HumansCTClinical Trials
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Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J Allergy Clin Immunol. 1991 Oct; 88(4):637-48.
Broide DH, Gleich GJ, Cuomo AJ, Coburn DA, Federman EC, Schwartz LB, Wasserman SI. PMID: 1717532.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Endobronchial allergen challenge in asthma. Demonstration of cellular source of granulocyte macrophage colony-stimulating factor by in situ hybridization. J Clin Invest. 1991 Sep; 88(3):1048-53.
Broide DH, Firestein GS. PMID: 1885766; PMCID: PMC295519.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Eosinophilia-myalgia syndrome. West J Med. 1991 Apr; 154(4):459.
Broide DH. PMID: 1877190; PMCID: PMC1002798.
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PubMed Mentions: Fields:
Translation:
Humans
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Mast cells and pulmonary fibrosis. Identification of a histamine releasing factor in bronchoalveolar lavage fluid. J Immunol. 1990 Sep 15; 145(6):1838-44.
Broide DH, Smith CM, Wasserman SI. PMID: 1697311.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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Airway levels of mast cell-derived mediators in exercise-induced asthma. Am Rev Respir Dis. 1990 Mar; 141(3):563-8.
Broide DH, Eisman S, Ramsdell JW, Ferguson P, Schwartz LB, Wasserman SI. PMID: 1689974.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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Transforming growth factor-beta 1 selectively inhibits IL-3-dependent mast cell proliferation without affecting mast cell function or differentiation. J Immunol. 1989 Sep 01; 143(5):1591-7.
Broide DH, Wasserman SI, Alvaro-Gracia J, Zvaifler NJ, Firestein GS. PMID: 2527268.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Characterization, activation, and functional importance of mucosal mast cells. Prog Clin Biol Res. 1989; 297:155-61; discussion 161.
Wasserman SI, Marquardt DL, Broide D, Walker L, Barrett K. PMID: 2685819.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Functional and biochemical characterization of rat bone marrow derived mast cells. J Immunol. 1988 Dec 15; 141(12):4298-305.
Broide DH, Metcalfe DD, Wasserman SI. PMID: 2974057.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Cytokines in chronic inflammatory arthritis. I. Failure to detect T cell lymphokines (interleukin 2 and interleukin 3) and presence of macrophage colony-stimulating factor (CSF-1) and a novel mast cell growth factor in rheumatoid synovitis. J Exp Med. 1988 Nov 01; 168(5):1573-86.
Firestein GS, Xu WD, Townsend K, Broide D, Alvaro-Gracia J, Glasebrook A, Zvaifler NJ. PMID: 3263464; PMCID: PMC2189111.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Current status of pharmacotherapy in the treatment of rhinitis. Ear Nose Throat J. 1986 May; 65(5):222-6.
Broide D, Schatz M, Zeigler R. PMID: 2873019.
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PubMed Mentions: Fields:
Translation:
Humans