Yukiko Miyamoto

Title(s)Project Scientist, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    1. Targeted inhibition of pathobiont virulence factor mitigates alcohol-associated liver disease. Cell Host Microbe. 2025 May 21. Yang Y, Duan Y, Lang S, Fondevila MF, Schöler D, Harberts A, Cabré N, Chen S, Shao Y, Vervier K, Miyamoto Y, Zhang X, Chu H, Yang L, Tan C, Eckmann L, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Stärkel P, Lawley TD, Schnabl B. PMID: 40441146.
      View in: PubMed   Mentions:
    2. Activation of intestinal endogenous retroviruses by alcohol exacerbates liver disease. J Clin Invest. 2025 May 13. Cabré N, Fondevila MF, Wei W, Yamazaki T, Raya Tonetti F, Eguileor A, Garcia-Carbonell R, Meijnikman AS, Miyamoto Y, Mayo S, Wang Y, Zhang X, Trimbuch T, Lehnardt S, Eckmann L, Fouts DE, Llorente C, Tsukamoto H, Stärkel P, Schnabl B. PMID: 40359032.
      View in: PubMed   Mentions:    Fields:    
    3. Distinct substrate specificities of the three catalytic subunits of the Trichomonas vaginalis proteasome. Protein Sci. 2024 Dec; 33(12):e5225. Fajtova P, Hurysz BM, Miyamoto Y, Serafim MSM, Jiang Z, Vazquez JM, Trujillo DF, Liu LJ, Somani U, Almaliti J, Myers SA, Caffrey CR, Gerwick WH, McMinn DL, Kirk CJ, Boura E, Eckmann L, O'Donoghue AJ. PMID: 39589076; PMCID: PMC11590128.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Evolutionary dynamics of polyadenylation signals and their recognition strategies in protists. Genome Res. 2024 Oct 29; 34(10):1570-1581. Sajek MP, Bilodeau DY, Beer MA, Horton E, Miyamoto Y, Velle KB, Eckmann L, Fritz-Laylin L, Rissland OS, Mukherjee N. PMID: 39327029; PMCID: PMC11529991.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors. Nat Commun. 2024 10 04; 15(1):8621. Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. PMID: 39366995; PMCID: PMC11452676.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    6. Vaginal Tritrichomonas foetus infection in mice as an in vivo model for drug development against Trichomonas vaginalis. PLoS One. 2024; 19(10):e0308672. Nieskens NM, Miyamoto Y, Hurysz BM, O'Donoghue AJ, Eckmann L. PMID: 39352907; PMCID: PMC11444383.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    7. Mucosal vaccination in a murine gnotobiotic model of Giardia lamblia infection. Infect Immun. 2024 06 11; 92(6):e0006524. Ihara S, Nguyen BV, Miyamoto Y, Eckmann L. PMID: 38722167; PMCID: PMC11237505.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsPHPublic Health
    8. Periportal macrophages protect against commensal-driven liver inflammation. Nature. 2024 May; 629(8013):901-909. Miyamoto Y, Kikuta J, Matsui T, Hasegawa T, Fujii K, Okuzaki D, Liu YC, Yoshioka T, Seno S, Motooka D, Uchida Y, Yamashita E, Kobayashi S, Eguchi H, Morii E, Tryggvason K, Shichita T, Kayama H, Atarashi K, Kunisawa J, Honda K, Takeda K, Ishii M. PMID: 38658756.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    9. Antigiardial and antiamebic activities of fexinidazole and its metabolites: new drug leads for giardiasis and amebiasis. Antimicrob Agents Chemother. 2024 01 10; 68(1):e0073123. Escrig JI, Miyamoto Y, Aznar AD, Eckmann L, Debnath A. PMID: 38063401; PMCID: PMC10777846.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    10. Structural elucidation of recombinant Trichomonas vaginalis 20S proteasome bound to covalent inhibitors. bioRxiv. 2023 Aug 17. Silhan J, Fajtova P, Bartosova J, Hurysz BM, Almaliti J, Miyamoto Y, Eckmann L, Gerwick WH, O'Donoghue AJ, Boura E. PMID: 37645851; PMCID: PMC10462138.
      View in: PubMed   Mentions:
    11. Development of subunit selective substrates for Trichomonas vaginalis proteasome. bioRxiv. 2023 Apr 06. Fajtova P, Hurysz BM, Miyamoto Y, Serafim M, Jiang Z, Trujillo DF, Liu L, Somani U, Almaliti J, Myers SA, Caffrey CR, Gerwick WH, Kirk CJ, Boura E, Eckmann L, O'Donoghue AJ. PMID: 37066163; PMCID: PMC10104049.
      View in: PubMed   Mentions:
    12. Identification of Tau protein as a novel marker for maturation and pathological changes of oligodendrocytes. Glia. 2023 04; 71(4):1002-1017. Torii T, Miyamoto Y, Nakata R, Higashi Y, Shinmyo Y, Kawasaki H, Miyasaka T, Misonou H. PMID: 36565228.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    13. Codelivery of Antigens and Adjuvant in Polymeric Nanoparticles Coated With Native Parasite Membranes Induces Protective Mucosal Immunity Against Giardia lamblia. J Infect Dis. 2022 08 24; 226(2):319-323. Zhou J, Miyamoto Y, Ihara S, Kroll AV, Nieskens N, Tran VN, Hanson EM, Fang RH, Zhang L, Eckmann L. PMID: 35262728; PMCID: PMC9400425.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    14. Intestinal transgene delivery with native E. coli chassis allows persistent physiological changes. Cell. 2022 08 18; 185(17):3263-3277.e15. Russell BJ, Brown SD, Siguenza N, Mai I, Saran AR, Lingaraju A, Maissy ES, Dantas Machado AC, Pinto AFM, Sanchez C, Rossitto LA, Miyamoto Y, Richter RA, Ho SB, Eckmann L, Hasty J, Gonzalez DJ, Saghatelian A, Knight R, Zarrinpar A. PMID: 35931082; PMCID: PMC9464905.
      View in: PubMed   Mentions: 50     Fields:    Translation:AnimalsCells
    15. Conserved metabolic enzymes as vaccine antigens for giardiasis. PLoS Negl Trop Dis. 2022 04; 16(4):e0010323. Ihara S, Miyamoto Y, Le CHY, Tran VN, Hanson EM, Fischer M, Hanevik K, Eckmann L. PMID: 35468132; PMCID: PMC9037923.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    16. Characterization of Metronidazole-Resistant Giardia intestinalis Lines by Comparative Transcriptomics and Proteomics. Front Microbiol. 2022; 13:834008. Krakovka S, Ribacke U, Miyamoto Y, Eckmann L, Svärd S. PMID: 35222342; PMCID: PMC8866875.
      View in: PubMed   Mentions: 15  
    17. Colesevelam ameliorates non-alcoholic steatohepatitis and obesity in mice. Hepatol Int. 2022 Apr; 16(2):359-370. Hartmann P, Duan Y, Miyamoto Y, Demir M, Lang S, Hasa E, Stern P, Yamashita D, Conrad M, Eckmann L, Schnabl B. PMID: 35075592; PMCID: PMC9013343.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimals
    18. Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production. Science. 2022 Jan 14; 375(6577):214-221. Orecchioni M, Kobiyama K, Winkels H, Ghosheh Y, McArdle S, Mikulski Z, Kiosses WB, Fan Z, Wen L, Jung Y, Roy P, Ali AJ, Miyamoto Y, Mangan M, Makings J, Wang Z, Denn A, Vallejo J, Owens M, Durant CP, Braumann S, Mader N, Li L, Matsunami H, Eckmann L, Latz E, Wang Z, Hazen SL, Ley K. PMID: 35025664; PMCID: PMC9744443.
      View in: PubMed   Mentions: 76     Fields:    
    19. The fecal mycobiome in non-alcoholic fatty liver disease. J Hepatol. 2022 04; 76(4):788-799. Demir M, Lang S, Hartmann P, Duan Y, Martin A, Miyamoto Y, Bondareva M, Zhang X, Wang Y, Kasper P, Bang C, Roderburg C, Tacke F, Steffen HM, Goeser T, Kruglov A, Eckmann L, Stärkel P, Fouts DE, Schnabl B. PMID: 34896404; PMCID: PMC8981795.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    20. Comprehensive characterization of purine and pyrimidine transport activities in Trichomonas vaginalis and functional cloning of a trichomonad nucleoside transporter. Mol Microbiol. 2021 12; 116(6):1489-1511. Natto MJ, Miyamoto Y, Munday JC, AlSiari TA, Al-Salabi MI, Quashie NB, Eze AA, Eckmann L, De Koning HP. PMID: 34738285; PMCID: PMC8688338.
      View in: PubMed   Mentions: 3     Fields:    
    21. K15 promoter-driven enforced expression of NKIRAS exhibits tumor suppressive activity against the development of DMBA/TPA-induced skin tumors. Sci Rep. 2021 10 19; 11(1):20658. Tago K, Ohta S, Aoki-Ohmura C, Funakoshi-Tago M, Sashikawa M, Matsui T, Miyamoto Y, Wada T, Oshio T, Komine M, Matsugi J, Furukawa Y, Ohtsuki M, Yamauchi J, Yanagisawa K. PMID: 34667224; PMCID: PMC8526694.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    22. Microbiota Modulates Cardiac Transcriptional Responses to Intermittent Hypoxia and Hypercapnia. Front Physiol. 2021; 12:680275. Zhou D, Xue J, Miyamoto Y, Poulsen O, Eckmann L, Haddad GG. PMID: 34248668; PMCID: PMC8267877.
      View in: PubMed   Mentions: 3  
    23. Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis. ACS Infect Dis. 2021 06 11; 7(6):1752-1764. Natto MJ, Hulpia F, Kalkman ER, Baillie S, Alhejeli A, Miyamoto Y, Eckmann L, Van Calenbergh S, de Koning HP. PMID: 33974405; PMCID: PMC9586919.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    24. Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis. J Med Chem. 2021 05 27; 64(10):6608-6620. Miyamoto Y, Aggarwal S, Celaje JJA, Ihara S, Ang J, Eremin DB, Land KM, Wrischnik LA, Zhang L, Fokin VV, Eckmann L. PMID: 33974434; PMCID: PMC9309012.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    25. Rnd2 differentially regulates oligodendrocyte myelination at different developmental periods. Mol Biol Cell. 2021 04 15; 32(8):769-787. Miyamoto Y, Torii T, Terao M, Takada S, Tanoue A, Katoh H, Yamauchi J. PMID: 33596091; PMCID: PMC8108512.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    26. Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis. PLoS Negl Trop Dis. 2020 04; 14(4):e0008224. Lauwaet T, Miyamoto Y, Ihara S, Le C, Kalisiak J, Korthals KA, Ghassemian M, Smith DK, Sharpless KB, Fokin VV, Eckmann L. PMID: 32302296; PMCID: PMC7190177.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    27. Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease. Nature. 2019 11; 575(7783):505-511. Duan Y, Llorente C, Lang S, Brandl K, Chu H, Jiang L, White RC, Clarke TH, Nguyen K, Torralba M, Shao Y, Liu J, Hernandez-Morales A, Lessor L, Rahman IR, Miyamoto Y, Ly M, Gao B, Sun W, Kiesel R, Hutmacher F, Lee S, Ventura-Cots M, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Ho SB, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Tu XM, Eckmann L, van der Donk WA, Young R, Lawley TD, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 31723265; PMCID: PMC6872939.
      View in: PubMed   Mentions: 349     Fields:    
    28. Composite thermoresponsive hydrogel with auranofin-loaded nanoparticles for topical treatment of vaginal trichomonad infection. Adv Ther (Weinh). 2019 Dec; 2(12). Zhang Y, Miyamoto Y, Ihara S, Yang JZ, Zuill DE, Angsantikul P, Zhang Q, Gao W, Zhang L, Eckmann L. PMID: 32377561; PMCID: PMC7202563.
      View in: PubMed   Mentions: 11  
    29. 20S Proteasome as a Drug Target in Trichomonas vaginalis. Antimicrob Agents Chemother. 2019 11; 63(11). O'Donoghue AJ, Bibo-Verdugo B, Miyamoto Y, Wang SC, Yang JZ, Zuill DE, Matsuka S, Jiang Z, Almaliti J, Caffrey CR, Gerwick WH, Eckmann L. PMID: 31451503; PMCID: PMC6811414.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    30. Evaluation of Peroxides and Chlorine Oxides as Disinfectants for Chemical Sterilization of Gnotobiotic Rodent Isolators. J Am Assoc Lab Anim Sci. 2019 09 01; 58(5):558-568. Moody LV, Miyamoto Y, Ang J, Richter PJ, Eckmann L. PMID: 31319899; PMCID: PMC6774453.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsPHPublic Health
    31. Phorbol 12-myristate 13-acetate (PMA) suppresses high Ca2+-enhanced adipogenesis in bone marrow stromal cells. J Physiol Sci. 2019 Sep; 69(5):741-748. Hashimoto R, Miyamoto Y, Itoh S, Daida H, Okada T, Katoh Y. PMID: 31256364; PMCID: PMC10717529.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia. Infect Immun. 2019 06; 87(6). Davids BJ, Liu CM, Hanson EM, Le CHY, Ang J, Hanevik K, Fischer M, Radunovic M, Langeland N, Ferella M, Svärd SG, Ghassemian M, Miyamoto Y, Eckmann L. PMID: 30962402; PMCID: PMC6529650.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    33. The Atypical Kinesin KIF26A Facilitates Termination of Nociceptive Responses by Sequestering Focal Adhesion Kinase. Cell Rep. 2018 09 11; 24(11):2894-2907. Wang L, Tanaka Y, Wang D, Morikawa M, Zhou R, Homma N, Miyamoto Y, Hirokawa N. PMID: 30208315.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    34. Validation of Babesia proteasome as a drug target. Int J Parasitol Drugs Drug Resist. 2018 12; 8(3):394-402. Jalovecka M, Hartmann D, Miyamoto Y, Eckmann L, Hajdusek O, O'Donoghue AJ, Sojka D. PMID: 30103207; PMCID: PMC6092455.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    35. Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera. PLoS Negl Trop Dis. 2018 02; 12(2):e0006266. Das S, Angsantikul P, Le C, Bao D, Miyamoto Y, Gao W, Zhang L, Eckmann L. PMID: 29470490; PMCID: PMC5839590.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    36. High extracellular Ca2+ enhances the adipocyte accumulation of bone marrow stromal cells through a decrease in cAMP. Cell Calcium. 2017 11; 67:74-80. Hashimoto R, Katoh Y, Miyamoto Y, Nakamura K, Itoh S, Daida H, Nakazato Y, Okada T. PMID: 29029793.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    37. Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia. Antimicrob Agents Chemother. 2017 06; 61(6). Kim WJ, Korthals KA, Li S, Le C, Kalisiak J, Sharpless KB, Fokin VV, Miyamoto Y, Eckmann L. PMID: 28396548; PMCID: PMC5444119.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    38. Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells. PLoS One. 2017; 12(2):e0171947. Yamashita T, Miyamoto Y, Bando Y, Ono T, Kobayashi S, Doi A, Araki T, Kato Y, Shirakawa T, Suzuki Y, Yamauchi J, Yoshida S, Sato N. PMID: 28192470; PMCID: PMC5305255.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    39. Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo. Int J Antimicrob Agents. 2016 Dec; 48(6):690-694. Hopper M, Yun JF, Zhou B, Le C, Kehoe K, Le R, Hill R, Jongeward G, Debnath A, Zhang L, Miyamoto Y, Eckmann L, Land KM, Wrischnik LA. PMID: 27839893; PMCID: PMC5154799.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    40. Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes. J Allergy Clin Immunol. 2017 Apr; 139(4):1205-1216.e6. Wang Z, Mascarenhas N, Eckmann L, Miyamoto Y, Sun X, Kawakami T, Di Nardo A. PMID: 27746235; PMCID: PMC5385284.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    41. Social isolation impairs remyelination in mice through modulation of IL-6. FASEB J. 2016 12; 30(12):4267-4274. Makinodan M, Ikawa D, Miyamoto Y, Yamauchi J, Yamamuro K, Yamashita Y, Toritsuka M, Kimoto S, Okumura K, Yamauchi T, Fukami SI, Yoshino H, Wanaka A, Kishimoto T. PMID: 27613805.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    42. Microbiota and Alcoholic Liver Disease. Alcohol Clin Exp Res. 2016 08; 40(8):1791-2. Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. PMID: 27364225.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    43. Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia. Front Microbiol. 2015; 6:1208. Miyamoto Y, Eckmann L. PMID: 26635732; PMCID: PMC4652082.
      View in: PubMed   Mentions: 30  
    44. Microbiota Protects Mice Against Acute Alcohol-Induced Liver Injury. Alcohol Clin Exp Res. 2015 Dec; 39(12):2313-23. Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. PMID: 26556636; PMCID: PMC4712135.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    45. Arf6 mediates Schwann cell differentiation and myelination. Biochem Biophys Res Commun. 2015 Sep 25; 465(3):450-7. Torii T, Miyamoto Y, Yamamoto M, Ohbuchi K, Tsumura H, Kawahara K, Tanoue A, Sakagami H, Yamauchi J. PMID: 26277388.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    46. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015 Oct 01; 26(19):3489-503. Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, Ito A, Ogata T, Terada N, Tanoue A, Yamauchi J. PMID: 26224309; PMCID: PMC4591693.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    47. Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites. Eur J Med Chem. 2015 Aug 28; 101:96-102. Jarrad AM, Karoli T, Debnath A, Tay CY, Huang JX, Kaeslin G, Elliott AG, Miyamoto Y, Ramu S, Kavanagh AM, Zuegg J, Eckmann L, Blaskovich MA, Cooper MA. PMID: 26117821; PMCID: PMC4550478.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    48. IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia. Exp Parasitol. 2015 Sep; 156:68-78. Dann SM, Manthey CF, Le C, Miyamoto Y, Gima L, Abrahim A, Cao AT, Hanson EM, Kolls JK, Raz E, Cong Y, Eckmann L. PMID: 26071205; PMCID: PMC4547885.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    49. Increased extracellular and intracellular Ca²⁺ lead to adipocyte accumulation in bone marrow stromal cells by different mechanisms. Biochem Biophys Res Commun. 2015 Feb 20; 457(4):647-52. Hashimoto R, Katoh Y, Miyamoto Y, Itoh S, Daida H, Nakazato Y, Okada T. PMID: 25603052.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    50. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. FASEB J. 2015 Mar; 29(3):1043-55. Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. PMID: 25466902; PMCID: PMC4422368.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansAnimalsCells
    51. Hsp90 inhibitors as new leads to target parasitic diarrheal diseases. Antimicrob Agents Chemother. 2014 Jul; 58(7):4138-44. Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH. PMID: 24820073; PMCID: PMC4068574.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    52. Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. Mol Biol Cell. 2014 May; 25(9):1532-42. Miyamoto Y, Yamamori N, Torii T, Tanoue A, Yamauchi J. PMID: 24600047; PMCID: PMC4004601.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    53. Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17564-9. Miyamoto Y, Kalisiak J, Korthals K, Lauwaet T, Cheung DY, Lozano R, Cobo ER, Upcroft P, Upcroft JA, Berg DE, Gillin FD, Fokin VV, Sharpless KB, Eckmann L. PMID: 24101497; PMCID: PMC3808650.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    54. Signaling through Arf6 guanine-nucleotide exchange factor cytohesin-1 regulates migration in Schwann cells. Cell Signal. 2013 Jun; 25(6):1379-87. Miyamoto Y, Torii T, Nakamura K, Takashima S, Sanbe A, Tanoue A, Yamauchi J. PMID: 23517829.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    55. Akt and PP2A reciprocally regulate the guanine nucleotide exchange factor Dock6 to control axon growth of sensory neurons. Sci Signal. 2013 Mar 05; 6(265):ra15. Miyamoto Y, Torii T, Yamamori N, Ogata T, Tanoue A, Yamauchi J. PMID: 23462102.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    56. A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia. Antimicrob Agents Chemother. 2013 May; 57(5):2029-35. Tejman-Yarden N, Miyamoto Y, Leitsch D, Santini J, Debnath A, Gut J, McKerrow JH, Reed SL, Eckmann L. PMID: 23403423; PMCID: PMC3632933.
      View in: PubMed   Mentions: 69     Fields:    
    57. Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. Sci Signal. 2012 Sep 25; 5(243):ra69. Yamauchi J, Miyamoto Y, Torii T, Takashima S, Kondo K, Kawahara K, Nemoto N, Chan JR, Tsujimoto G, Tanoue A. PMID: 23012656.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    58. The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. J Neurosci. 2011 Aug 31; 31(35):12579-92. Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, Tsumura H, Maeda M, Nemoto N, Kawahara K, Torii T, Tanoue A. PMID: 21880919; PMCID: PMC6703263.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    59. Impaired parasite attachment as fitness cost of metronidazole resistance in Giardia lamblia. Antimicrob Agents Chemother. 2011 Oct; 55(10):4643-51. Tejman-Yarden N, Millman M, Lauwaet T, Davids BJ, Gillin FD, Dunn L, Upcroft JA, Miyamoto Y, Eckmann L. PMID: 21825286; PMCID: PMC3186953.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    60. Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia. J Med Chem. 2009 Jul 09; 52(13):4038-53. Valdez CA, Tripp JC, Miyamoto Y, Kalisiak J, Hruz P, Andersen YS, Brown SE, Kangas K, Arzu LV, Davids BJ, Gillin FD, Upcroft JA, Upcroft P, Fokin VV, Smith DK, Sharpless KB, Eckmann L. PMID: 19480409; PMCID: PMC2766634.
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    61. Sorting nexin 3, a protein upregulated by lithium, contains a novel phosphatidylinositol-binding sequence and mediates neurite outgrowth in N1E-115 cells. Cell Signal. 2009 Nov; 21(11):1586-94. Mizutani R, Yamauchi J, Kusakawa S, Nakamura K, Sanbe A, Torii T, Miyamoto Y, Tanoue A. PMID: 19576982.
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    62. Deoxycholic acid formation in gnotobiotic mice associated with human intestinal bacteria. Lipids. 2006 Sep; 41(9):835-43. Narushima S, Itoha K, Miyamoto Y, Park SH, Nagata K, Kuruma K, Uchida K. PMID: 17152920.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    63. Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury. J Immunol. 2006 Jul 15; 177(2):1214-20. Chae S, Eckmann L, Miyamoto Y, Pothoulakis C, Karin M, Kagnoff MF. PMID: 16818780.
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    64. Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo. Cell Microbiol. 2006 May; 8(5):869-79. Miyamoto Y, Iimura M, Kaper JB, Torres AG, Kagnoff MF. PMID: 16611235.
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    65. Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol. 2005 Apr 15; 174(8):4901-7. Iimura M, Gallo RL, Hase K, Miyamoto Y, Eckmann L, Kagnoff MF. PMID: 15814717.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    66. The adaptor protein Nck1 mediates endothelin A receptor-regulated cell migration through the Cdc42-dependent c-Jun N-terminal kinase pathway. J Biol Chem. 2004 Aug 13; 279(33):34336-42. Miyamoto Y, Yamauchi J, Mizuno N, Itoh H. PMID: 15187089.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    67. Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell Microbiol. 2002 Oct; 4(10):635-48. Berin MC, Darfeuille-Michaud A, Egan LJ, Miyamoto Y, Kagnoff MF. PMID: 12366401.
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