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Yukiko Miyamoto

Title(s)Project Scientist, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Deazapurine Nucleoside Analogues for the Treatment of Trichomonas vaginalis. ACS Infect Dis. 2021 May 11. Natto MJ, Hulpia F, Kalkman ER, Baillie S, Alhejeli A, Miyamoto Y, Eckmann L, Van Calenbergh S, de Koning HP. PMID: 33974405.
      View in: PubMed   Mentions:    Fields:    
    2. Gold(I) Phosphine Derivatives with Improved Selectivity as Topically Active Drug Leads to Overcome 5-Nitroheterocyclic Drug Resistance in Trichomonas vaginalis. J Med Chem. 2021 May 11. Miyamoto Y, Aggarwal S, Celaje JJA, Ihara S, Ang J, Eremin DB, Land KM, Wrischnik LA, Zhang L, Fokin VV, Eckmann L. PMID: 33974434.
      View in: PubMed   Mentions:    Fields:    
    3. Click chemistry-facilitated comprehensive identification of proteins adducted by antimicrobial 5-nitroimidazoles for discovery of alternative drug targets against giardiasis. PLoS Negl Trop Dis. 2020 04; 14(4):e0008224. Lauwaet T, Miyamoto Y, Ihara S, Le C, Kalisiak J, Korthals KA, Ghassemian M, Smith DK, Sharpless KB, Fokin VV, Eckmann L. PMID: 32302296.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    4. Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease. Nature. 2019 11; 575(7783):505-511. Duan Y, Llorente C, Lang S, Brandl K, Chu H, Jiang L, White RC, Clarke TH, Nguyen K, Torralba M, Shao Y, Liu J, Hernandez-Morales A, Lessor L, Rahman IR, Miyamoto Y, Ly M, Gao B, Sun W, Kiesel R, Hutmacher F, Lee S, Ventura-Cots M, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, Caballería J, Shawcross DL, Ho SB, Louvet A, Lucey MR, Mathurin P, Garcia-Tsao G, Bataller R, Tu XM, Eckmann L, van der Donk WA, Young R, Lawley TD, Stärkel P, Pride D, Fouts DE, Schnabl B. PMID: 31723265.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    5. Composite thermoresponsive hydrogel with auranofin-loaded nanoparticles for topical treatment of vaginal trichomonad infection. Adv Ther (Weinh). 2019 Dec; 2(12). Zhang Y, Miyamoto Y, Ihara S, Yang JZ, Zuill DE, Angsantikul P, Zhang Q, Gao W, Zhang L, Eckmann L. PMID: 32377561.
      View in: PubMed   Mentions:
    6. 20S Proteasome as a Drug Target in Trichomonas vaginalis. Antimicrob Agents Chemother. 2019 11; 63(11). O'Donoghue AJ, Bibo-Verdugo B, Miyamoto Y, Wang SC, Yang JZ, Zuill DE, Matsuka S, Jiang Z, Almaliti J, Caffrey CR, Gerwick WH, Eckmann L. PMID: 31451503.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    7. Evaluation of Peroxides and Chlorine Oxides as Disinfectants for Chemical Sterilization of Gnotobiotic Rodent Isolators. J Am Assoc Lab Anim Sci. 2019 09 01; 58(5):558-568. Moody LV, Miyamoto Y, Ang J, Richter PJ, Eckmann L. PMID: 31319899.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsPHPublic Health
    8. Phorbol 12-myristate 13-acetate (PMA) suppresses high Ca2+-enhanced adipogenesis in bone marrow stromal cells. J Physiol Sci. 2019 Sep; 69(5):741-748. Hashimoto R, Miyamoto Y, Itoh S, Daida H, Okada T, Katoh Y. PMID: 31256364.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    9. Identification of Conserved Candidate Vaccine Antigens in the Surface Proteome of Giardia lamblia. Infect Immun. 2019 06; 87(6). Davids BJ, Liu CM, Hanson EM, Le CHY, Ang J, Hanevik K, Fischer M, Radunovic M, Langeland N, Ferella M, Svärd SG, Ghassemian M, Miyamoto Y, Eckmann L. PMID: 30962402.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    10. The Atypical Kinesin KIF26A Facilitates Termination of Nociceptive Responses by Sequestering Focal Adhesion Kinase. Cell Rep. 2018 09 11; 24(11):2894-2907. Wang L, Tanaka Y, Wang D, Morikawa M, Zhou R, Homma N, Miyamoto Y, Hirokawa N. PMID: 30208315.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    11. Validation of Babesia proteasome as a drug target. Int J Parasitol Drugs Drug Resist. 2018 12; 8(3):394-402. Jalovecka M, Hartmann D, Miyamoto Y, Eckmann L, Hajdusek O, O'Donoghue AJ, Sojka D. PMID: 30103207.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    12. Neutralization of cholera toxin with nanoparticle decoys for treatment of cholera. PLoS Negl Trop Dis. 2018 02; 12(2):e0006266. Das S, Angsantikul P, Le C, Bao D, Miyamoto Y, Gao W, Zhang L, Eckmann L. PMID: 29470490.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    13. Click Chemistry-Facilitated Structural Diversification of Nitrothiazoles, Nitrofurans, and Nitropyrroles Enhances Antimicrobial Activity against Giardia lamblia. Antimicrob Agents Chemother. 2017 06; 61(6). Kim WJ, Korthals KA, Li S, Le C, Kalisiak J, Sharpless KB, Fokin VV, Miyamoto Y, Eckmann L. PMID: 28396548.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    14. Auranofin inactivates Trichomonas vaginalis thioredoxin reductase and is effective against trichomonads in vitro and in vivo. Int J Antimicrob Agents. 2016 Dec; 48(6):690-694. Hopper M, Yun JF, Zhou B, Le C, Kehoe K, Le R, Hill R, Jongeward G, Debnath A, Zhang L, Miyamoto Y, Eckmann L, Land KM, Wrischnik LA. PMID: 27839893.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    15. Skin microbiome promotes mast cell maturation by triggering stem cell factor production in keratinocytes. J Allergy Clin Immunol. 2017 Apr; 139(4):1205-1216.e6. Wang Z, Mascarenhas N, Eckmann L, Miyamoto Y, Sun X, Kawakami T, Di Nardo A. PMID: 27746235.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    16. Social isolation impairs remyelination in mice through modulation of IL-6. FASEB J. 2016 12; 30(12):4267-4274. Makinodan M, Ikawa D, Miyamoto Y, Yamauchi J, Yamamuro K, Yamashita Y, Toritsuka M, Kimoto S, Okumura K, Yamauchi T, Fukami SI, Yoshino H, Wanaka A, Kishimoto T. PMID: 27613805.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    17. Microbiota and Alcoholic Liver Disease. Alcohol Clin Exp Res. 2016 08; 40(8):1791-2. Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. PMID: 27364225.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    18. Drug Development Against the Major Diarrhea-Causing Parasites of the Small Intestine, Cryptosporidium and Giardia. Front Microbiol. 2015; 6:1208. Miyamoto Y, Eckmann L. PMID: 26635732.
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    19. Microbiota Protects Mice Against Acute Alcohol-Induced Liver Injury. Alcohol Clin Exp Res. 2015 Dec; 39(12):2313-23. Chen P, Miyamoto Y, Mazagova M, Lee KC, Eckmann L, Schnabl B. PMID: 26556636.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    20. Arf6 mediates Schwann cell differentiation and myelination. Biochem Biophys Res Commun. 2015 Sep 25; 465(3):450-7. Torii T, Miyamoto Y, Yamamoto M, Ohbuchi K, Tsumura H, Kawahara K, Tanoue A, Sakagami H, Yamauchi J. PMID: 26277388.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    21. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015 Oct 01; 26(19):3489-503. Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, Ito A, Ogata T, Terada N, Tanoue A, Yamauchi J. PMID: 26224309.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    22. Metronidazole-triazole conjugates: activity against Clostridium difficile and parasites. Eur J Med Chem. 2015 Aug 28; 101:96-102. Jarrad AM, Karoli T, Debnath A, Tay CY, Huang JX, Kaeslin G, Elliott AG, Miyamoto Y, Ramu S, Kavanagh AM, Zuegg J, Eckmann L, Blaskovich MA, Cooper MA. PMID: 26117821.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    23. IL-17A promotes protective IgA responses and expression of other potential effectors against the lumen-dwelling enteric parasite Giardia. Exp Parasitol. 2015 Sep; 156:68-78. Dann SM, Manthey CF, Le C, Miyamoto Y, Gima L, Abrahim A, Cao AT, Hanson EM, Kolls JK, Raz E, Cong Y, Eckmann L. PMID: 26071205.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    24. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. FASEB J. 2015 Mar; 29(3):1043-55. Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. PMID: 25466902.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    25. Hsp90 inhibitors as new leads to target parasitic diarrheal diseases. Antimicrob Agents Chemother. 2014 Jul; 58(7):4138-44. Debnath A, Shahinas D, Bryant C, Hirata K, Miyamoto Y, Hwang G, Gut J, Renslo AR, Pillai DR, Eckmann L, Reed SL, McKerrow JH. PMID: 24820073.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    26. Rab35, acting through ACAP2 switching off Arf6, negatively regulates oligodendrocyte differentiation and myelination. Mol Biol Cell. 2014 May; 25(9):1532-42. Miyamoto Y, Yamamori N, Torii T, Tanoue A, Yamauchi J. PMID: 24600047.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    27. Expanded therapeutic potential in activity space of next-generation 5-nitroimidazole antimicrobials with broad structural diversity. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17564-9. Miyamoto Y, Kalisiak J, Korthals K, Lauwaet T, Cheung DY, Lozano R, Cobo ER, Upcroft P, Upcroft JA, Berg DE, Gillin FD, Fokin VV, Sharpless KB, Eckmann L. PMID: 24101497.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    28. Signaling through Arf6 guanine-nucleotide exchange factor cytohesin-1 regulates migration in Schwann cells. Cell Signal. 2013 Jun; 25(6):1379-87. Miyamoto Y, Torii T, Nakamura K, Takashima S, Sanbe A, Tanoue A, Yamauchi J. PMID: 23517829.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    29. Akt and PP2A reciprocally regulate the guanine nucleotide exchange factor Dock6 to control axon growth of sensory neurons. Sci Signal. 2013 Mar 05; 6(265):ra15. Miyamoto Y, Torii T, Yamamori N, Ogata T, Tanoue A, Yamauchi J. PMID: 23462102.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    30. A reprofiled drug, auranofin, is effective against metronidazole-resistant Giardia lamblia. Antimicrob Agents Chemother. 2013 May; 57(5):2029-35. Tejman-Yarden N, Miyamoto Y, Leitsch D, Santini J, Debnath A, Gut J, McKerrow JH, Reed SL, Eckmann L. PMID: 23403423.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimals
    31. The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. J Neurosci. 2011 Aug 31; 31(35):12579-92. Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, Tsumura H, Maeda M, Nemoto N, Kawahara K, Torii T, Tanoue A. PMID: 21880919.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    32. Impaired parasite attachment as fitness cost of metronidazole resistance in Giardia lamblia. Antimicrob Agents Chemother. 2011 Oct; 55(10):4643-51. Tejman-Yarden N, Millman M, Lauwaet T, Davids BJ, Gillin FD, Dunn L, Upcroft JA, Miyamoto Y, Eckmann L. PMID: 21825286.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    33. Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia. J Med Chem. 2009 Jul 09; 52(13):4038-53. Valdez CA, Tripp JC, Miyamoto Y, Kalisiak J, Hruz P, Andersen YS, Brown SE, Kangas K, Arzu LV, Davids BJ, Gillin FD, Upcroft JA, Upcroft P, Fokin VV, Smith DK, Sharpless KB, Eckmann L. PMID: 19480409.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    34. Epithelial cell I kappa B-kinase beta has an important protective role in Clostridium difficile toxin A-induced mucosal injury. J Immunol. 2006 Jul 15; 177(2):1214-20. Chae S, Eckmann L, Miyamoto Y, Pothoulakis C, Karin M, Kagnoff MF. PMID: 16818780.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    35. Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo. Cell Microbiol. 2006 May; 8(5):869-79. Miyamoto Y, Iimura M, Kaper JB, Torres AG, Kagnoff MF. PMID: 16611235.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    36. Cathelicidin mediates innate intestinal defense against colonization with epithelial adherent bacterial pathogens. J Immunol. 2005 Apr 15; 174(8):4901-7. Iimura M, Gallo RL, Hase K, Miyamoto Y, Eckmann L, Kagnoff MF. PMID: 15814717.
      View in: PubMed   Mentions: 90     Fields:    Translation:HumansAnimalsCells
    37. The adaptor protein Nck1 mediates endothelin A receptor-regulated cell migration through the Cdc42-dependent c-Jun N-terminal kinase pathway. J Biol Chem. 2004 Aug 13; 279(33):34336-42. Miyamoto Y, Yamauchi J, Mizuno N, Itoh H. PMID: 15187089.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    38. Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8. Cell Microbiol. 2002 Oct; 4(10):635-48. Berin MC, Darfeuille-Michaud A, Egan LJ, Miyamoto Y, Kagnoff MF. PMID: 12366401.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansCells
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