Albert Leung

Title(s)Clinical Professor, Anesthesiology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    University of Pittsburgh School of Medicine, Pittsburgh, PAM.D.05/1993Medicine
    University of California, San Diego, La Jolla, CA06/1999Combined Research and Clinical Pain Fellowship
    Collapse Awards and Honors
    NCCIH2003  - 2007NIH K08 Mentored Clinical Scientist Award
    AAMA2005First Prize Award in the American Academy of Medical Acupuncture Annual Meeting Research Paper Compe
    AAMA2007First Prize Award in the American Academy of Medical Acupuncture Annual Meeting Research Paper Compe
    American Pain Society2010American Pain Society Center of Excellence
    American Pain Society2014American Pain Society Center of Excellence
    International Association of Anesthesiologists2016Selected “Top Doctor in La Jolla, CA” by the International Association of Anesthesiologists
    VA ORD2014VA Rehabilitation Research and Development SPIRE Award
    VA ORD2016VA Rehabilitation Research and Development SPIRE Award
    VA ORD2017VA Rehabilitation Research and Development Merit Award
    DOD2019Congressionally Directed Medical Research Program Clinical Trail Award
    VA ORD2019VA Clinical Science Research and Development Award for Research on Gulf War Veterans’ Illnesses
    AAPM2019American Academy of Pain Medicine Fellowship Excellence Award

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    A Phase 3 Placebo-Controlled, Double-Blind Randomized Withdrawal Study To Evaluate The Ef?cacy And Safety Of BIIB074 (Vixotrigine) In Subjects With Trigeminal Neuralgia
    Biogen Pharmaceuticals Aug 4, 2020
    Role: Principal Investigator
    Long-Term Efficacy of Neuronavigation-Guided rTMS in Alleviating Headache and Pain In GWI (Multicenter Study)
    DOD W81XWH1910691Oct 2, 2019
    Role: Lead Principal Investigator
    rTMS in alleviating Pain and Co-morbid symptoms in GWVI
    NIH I01CX001986Oct 1, 2019 - Sep 30, 2024
    Role: Lead Principal Investigator
    Long Term efficacy of rTMS in Managing MTBI-related Headache
    NIH I01RX002506Jan 1, 2018 - Sep 30, 2023
    Role: Principal Investigator
    A Phase 2, Multicenter, Randomized, Proof-of-Concept, Double-Blind, Placebo-Controlled, Parallel-Group Study Comparing the Efficacy and Safety of 1 Subcutaneous Dose Regimen of Fremanezumab Versus Placebo for the Prevention of Persistent Posttraumatic Headache
    TEVA Pharmaceutical Jan 30, 2017
    Role: Principal Investigator
    Improving functions in Veterans with Post-Traumatic Peripheral Neuropathic Pain
    NIH I21RX002366Oct 1, 2016 - Sep 30, 2019
    Role: Principal Investigator
    Alleviating headache and pain in GWI with Neuronagvigation-Guided rTMS
    DOD W81XWH-16-1-0754Oct 1, 2016 - Sep 30, 2019
    Role: Principal Investigator
    Improving Functions in MTBI Patients with Headache by rTMS
    NIH I21RX001359Jan 1, 2014 - Sep 30, 2016
    Role: Principal Investigator
    A randomized double-blind placebo controlled parallel group study of the efficacy and safety of pregabalin in subjects with post-traumatic peripheral neuropathic pain
    Pfizer Pharmaceutical Feb 1, 2012
    Role: Principal Investigator
    Sanofi-Aventis: Randomized, double blind, placebo-controlled study of the effect of a single injection of SAR164877 (REGN475) on reduction of pain in patients with pancreatitis
    Sanofi-Aventis May 4, 2010
    Role: Principal Investigator
    Sanofi Aventis: Randomized, double blind, placebo-controlled study of the effect of a single injection of SAR164877 (REGN475) on reduction of pain from vertebral fracture associated with osteoporosis
    Sanofi Aventis Mar 1, 2010
    Role: Principal Investigator
    Archimedes: CP043/06/FCNS: A Multicenter, Placebo-Controlled, Double-Blind, Two Phase Crossover Study of Nasalfent (Fentanyl Citrate Nasal Spray) in the Treatment of Breakthrough Cancer Pain (BTCP) in Subjects Taking Regular Opioid Therapy
    Archimedes Jul 2, 2007
    Role: Principal Investigator
    Archimedes: CP045/06/FCNS: An Open-Label Study Investigating Long-term Safety and Tolerability of Nasalfent (Fentanyl Citrate Nasal Spray) in the Treatment of Breakthrough Cancer Pain (BTCP) in Subjects Taking Regular Opioid Therapy
    Archimedes May 1, 2007
    Role: Principal Investigator
    ANS: A Clinical Evaluation of the Eon 16-Channel Implantable Pulse Generator (IPG) in combination with two Octrode leads for the management of back pain and neuropathic leg pain
    ANS Jun 1, 2006
    Role: Principal Investigator
    To study the neuronal mechanism of acupunture analgesia
    NIH K08AT001695Sep 1, 2003 - Aug 31, 2007
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications
    Collapse Faculty Mentoring

    Collapse Featured Content 
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Transcranial and Transcutaneous Stimulation for Pain: What Have We Learned From the COVID-19 Pandemic Shutdown? Pain Physician. 2023 05; 26(3):E223-E231. Leung A, Alhaqab S, Kunne A, Leung D, Krug P, Golshan S. PMID: 37192245.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
    2. Unveiling the phantom: What neuroimaging has taught us about phantom limb pain. Brain Behav. 2022 03; 12(3):e2509. Browne JD, Fraiser R, Cai Y, Leung D, Leung A, Vaninetti M. PMID: 35218308; PMCID: PMC8933774.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    3. fMRI findings in MTBI patients with headaches following rTMS. Sci Rep. 2021 05 05; 11(1):9573. Vaninetti M, Lim M, Khalaf A, Metzger-Smith V, Flowers M, Kunnel A, Yang E, Song D, Lin L, Tsai A, Lee R, Golshan S, Leung A. PMID: 33953315; PMCID: PMC8100290.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    4. Severities in persistent mild traumatic brain injury related headache is associated with changes in supraspinal pain modulatory functions. Mol Pain. 2021 Jan-Dec; 17:17448069211037881. Flowers M, Leung A, Schiehser DM, Metzger-Smith V, Delano-Wood L, Sorg S, Kunnel A, Wong A, Vaninetti M, Golshan S, Lee R. PMID: 34365850; PMCID: PMC8358489.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Customizing TMS Applications in Traumatic Brain Injury Using Neuroimaging. J Head Trauma Rehabil. 2020 Nov-Dec; 35(6):401-411. Herrold AA, Siddiqi SH, Livengood SL, Bender Pape TL, Higgins JP, Adamson MM, Leung A, Raij T. PMID: 33165153.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    6. Diminished corticomotor excitability in Gulf War Illness related chronic pain symptoms; evidence from TMS study. Sci Rep. 2020 10 28; 10(1):18520. Lei K, Kunnel A, Metzger-Smith V, Golshan S, Javors J, Wei J, Lee R, Vaninetti M, Rutledge T, Leung A. PMID: 33116195; PMCID: PMC7595115.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCTClinical Trials
    7. Addressing chronic persistent headaches after MTBI as a neuropathic pain state. J Headache Pain. 2020 Jun 19; 21(1):77. Leung A. PMID: 32560626; PMCID: PMC7304149.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    8. Transcranial Magnetic Stimulation for Pain, Headache, and Comorbid Depression: INS-NANS Expert Consensus Panel Review and Recommendation. Neuromodulation. 2020 Apr; 23(3):267-290. Leung A, Shirvalkar P, Chen R, Kuluva J, Vaninetti M, Bermudes R, Poree L, Wassermann EM, Kopell B, Levy R, and the Expert Consensus Panel. PMID: 32212288.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    9. The prevalence of headaches, pain, and other associated symptoms in different Persian Gulf deployment periods and deployment durations. SAGE Open Med. 2019; 7:2050312119871418. Lei K, Metzger-Smith V, Golshan S, Javors J, Leung A. PMID: 31489191; PMCID: PMC6712755.
      View in: PubMed   Mentions: 2  
    10. Pain-related white matter tract abnormalities in mild traumatic brain injury patients with persistent headache. Mol Pain. 2018 Jan-Dec; 14:1744806918810297. Leung A, Yang E, Lim M, Metzger-Smith V, Theilmann R, Song D, Lin L, Tsai A, Lee R. PMID: 30324850; PMCID: PMC6311536.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    11. Exposure reporting disparity in Gulf War Registry-related clinical assessments. SAGE Open Med. 2017; 5:2050312117746567. Metzger-Smith V, Lei K, Javors J, Golshan S, Leung A. PMID: 29318011; PMCID: PMC5753886.
      View in: PubMed   Mentions: 1  
    12. Left Dorsolateral Prefrontal Cortex rTMS in Alleviating MTBI Related Headaches and Depressive Symptoms. Neuromodulation. 2018 Jun; 21(4):390-401. Leung A, Metzger-Smith V, He Y, Cordero J, Ehlert B, Song D, Lin L, Shahrokh G, Tsai A, Vaninetti M, Rutledge T, Polston G, Sheu R, Lee R. PMID: 28557049.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    13. A feasible repetitive transcranial magnetic stimulation clinical protocol in migraine prevention. SAGE Open Med Case Rep. 2016; 4:2050313X16675257. Zardouz S, Shi L, Leung A. PMID: 27826448; PMCID: PMC5084613.
      View in: PubMed   Mentions: 4  
    14. Diminished supraspinal pain modulation in patients with mild traumatic brain injury. Mol Pain. 2016; 12. Leung A, Shukla S, Yang E, Canlas B, Kadokana M, Heald J, Davani A, Song D, Lin L, Polston G, Tsai A, Lee R. PMID: 27531671; PMCID: PMC4989585.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    15. rTMS in Alleviating Mild TBI Related Headaches--A Case Series. Pain Physician. 2016 Feb; 19(2):E347-54. Leung A, Fallah A, Shukla S, Lin L, Tsia A, Song D, Polston G, Lee R. PMID: 26815263.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    16. Repetitive Transcranial Magnetic Stimulation in Managing Mild Traumatic Brain Injury-Related Headaches. Neuromodulation. 2016 Feb; 19(2):133-41. Leung A, Shukla S, Fallah A, Song D, Lin L, Golshan S, Tsai A, Jak A, Polston G, Lee R. PMID: 26555886.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    17. Effect of low frequency transcutaneous magnetic stimulation on sensory and motor transmission. Bioelectromagnetics. 2015 Sep; 36(6):410-9. Leung A, Shukla S, Lee J, Metzger-Smith V, He Y, Chen J, Golshan S. PMID: 25989482.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    18. A phase 2, randomized, placebo-controlled, dose-ranging study of the calcium-sensing receptor antagonist MK-5442 in the treatment of postmenopausal women with osteoporosis. J Clin Endocrinol Metab. 2014 Nov; 99(11):E2207-15. Halse J, Greenspan S, Cosman F, Ellis G, Santora A, Leung A, Heyden N, Samanta S, Doleckyj S, Rosenberg E, Denker AE. PMID: 25166719; PMCID: PMC5393499.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    19. Transcutaneous magnetic stimulation (TMS) in alleviating post-traumatic peripheral neuropathic pain States: a case series. Pain Med. 2014 Jul; 15(7):1196-9. Leung A, Fallah A, Shukla S. PMID: 24666606.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    20. The effect of acupuncture needle combination on central pain processing--an fMRI study. Mol Pain. 2014 Mar 25; 10:23. Leung A, Zhao Y, Shukla S. PMID: 24667015; PMCID: PMC3986941.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    21. Supraspinal characterization of the thermal grill illusion with fMRI. Mol Pain. 2014 Mar 11; 10:18. Leung A, Shukla S, Li E, Duann JR, Yaksh T. PMID: 24612493; PMCID: PMC3995740.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    22. Incidence of displacement after nondisplaced distal radial fractures in adults. J Bone Joint Surg Am. 2013 Aug 07; 95(15):1398-402. Roth KM, Blazar PE, Earp BE, Han R, Leung A. PMID: 23925744.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    23. Incidence of extensor pollicis longus tendon rupture after nondisplaced distal radius fractures. J Hand Surg Am. 2012 May; 37(5):942-7. Roth KM, Blazar PE, Earp BE, Han R, Leung A. PMID: 22463927.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    24. The analgesic effect of electroacupuncture on acute thermal pain perception--a central neural correlate study with fMRI. Mol Pain. 2011 Jun 07; 7:45. Shukla S, Torossian A, Duann JR, Leung A. PMID: 21645415; PMCID: PMC3130679.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    25. A toolbox for ab initio 3-D reconstructions in single-particle electron microscopy. J Struct Biol. 2010 Mar; 169(3):389-98. Voss NR, Lyumkis D, Cheng A, Lau PW, Mulder A, Lander GC, Brignole EJ, Fellmann D, Irving C, Jacovetty EL, Leung A, Pulokas J, Quispe JD, Winkler H, Yoshioka C, Carragher B, Potter CS. PMID: 20018246; PMCID: PMC2826578.
      View in: PubMed   Mentions: 28     Fields:    Translation:Cells
    26. rTMS for suppressing neuropathic pain: a meta-analysis. J Pain. 2009 Dec; 10(12):1205-16. Leung A, Donohue M, Xu R, Lee R, Lefaucheur JP, Khedr EM, Saitoh Y, André-Obadia N, Rollnik J, Wallace M, Chen R. PMID: 19464959.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    27. The effect of acupuncture duration on analgesia and peripheral sensory thresholds. BMC Complement Altern Med. 2008 May 01; 8:18. Leung AY, Kim SJ, Schulteis G, Yaksh T. PMID: 18452622; PMCID: PMC2386116.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    28. Towards automated screening of two-dimensional crystals. J Struct Biol. 2007 Dec; 160(3):324-31. Cheng A, Leung A, Fellmann D, Quispe J, Suloway C, Pulokas J, Abeyrathne PD, Lam JS, Carragher B, Potter CS. PMID: 17977016; PMCID: PMC2141647.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    29. The electrophysiology of de qi sensations. J Altern Complement Med. 2006 Oct; 12(8):743-50. Leung AY, Park J, Schulteis G, Duann JR, Yaksh T. PMID: 17034280.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    30. The effect of Ting point (tendinomuscular meridians) electroacupuncture on thermal pain: a model for studying the neuronal mechanism of acupuncture analgesia. J Altern Complement Med. 2005 Aug; 11(4):653-61. Leung A, Khadivi B, Duann JR, Cho ZH, Yaksh T. PMID: 16131289.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCTClinical Trials
    31. Qualitative and quantitative characterization of the thermal grill. Pain. 2005 Jul; 116(1-2):26-32. Leung AY, Wallace MS, Schulteis G, Yaksh TL. PMID: 15935558.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    32. Postoperative pain management in obstetric anesthesia--new challenges and solutions. J Clin Anesth. 2004 Feb; 16(1):57-65. Leung AY. PMID: 14984863.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    33. Concentration-effect relationships for intravenous alfentanil and ketamine infusions in human volunteers: effects on acute thresholds and capsaicin-evoked hyperpathia. J Clin Pharmacol. 2002 Jan; 42(1):70-80. Wallace MS, Ridgeway B, Leung A, Schulteis G, Yaksh TL. PMID: 11808827.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCTClinical Trials
    34. Concentration-effect relationship of intravenous alfentanil and ketamine on peripheral neurosensory thresholds, allodynia and hyperalgesia of neuropathic pain. Pain. 2001 Mar; 91(1-2):177-87. Leung A, Wallace MS, Ridgeway B, Yaksh T. PMID: 11240090.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    35. Concentration-effect relationship of intravenous lidocaine on the allodynia of complex regional pain syndrome types I and II. Anesthesiology. 2000 Jan; 92(1):75-83. Wallace MS, Ridgeway BM, Leung AY, Gerayli A, Yaksh TL. PMID: 10638902.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCTClinical Trials
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