Matthew Banghart

Title(s)	Associate Professor, Neurobiology
School	Vc-academic Affairs
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Next generation all-optical toolkits for functional analysis of neuropeptide dynamics in neural circuits
NIH U01NS113295Aug 15, 2019 - May 31, 2023
Role: Principal Investigator

Molecular mechanisms of dense-core vesicle release
NIH R35GM133802Aug 1, 2019 - Jun 30, 2024
Role: Principal Investigator

A novel platform for genetically-encoded optical neuropeptide sensors (NEONS)
NIH R21EY028399Sep 1, 2017 - Aug 31, 2020
Role: Principal Investigator

Compartment-specific signaling of striatal opioid peptides in reward-guided behavior
NIH R00DA034648Mar 1, 2017 - Feb 28, 2021
Role: Principal Investigator

Compartment-Specific Signaling Of Striatal Opioid Peptides in Reward-Guided Behav
NIH K99DA034648Jan 1, 2013 - Jun 30, 2016
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Unlocking opioid neuropeptide dynamics with genetically encoded biosensors. Nat Neurosci. 2024 Sep; 27(9):1844-1857. Dong C, Gowrishankar R, Jin Y, He XJ, Gupta A, Wang H, Sayar-Atasoy N, Flores RJ, Mahe K, Tjahjono N, Liang R, Marley A, Or Mizuno G, Lo DK, Sun Q, Whistler JL, Li B, Gomes I, Von Zastrow M, Tejeda HA, Atasoy D, Devi LA, Bruchas MR, Banghart MR, Tian L. PMID: 39009835; PMCID: PMC11374718.

View in: PubMed Mentions: 4 Fields:
Neu Neurology
Translation:Humans Animals Cells
Mimicking opioid analgesia in cortical pain circuits. bioRxiv. 2024 Apr 29. James JG, McCall NM, Hsu AI, Oswell CS, Salimando GJ, Mahmood M, Wooldridge LM, Wachira M, Jo A, Sandoval Ortega RA, Wojick JA, Beattie K, Farinas SA, Chehimi SN, Rodrigues A, Ejoh LL, Kimmey BA, Lo E, Azouz G, Vasquez JJ, Banghart MR, Creasy KT, Beier KT, Ramakrishnan C, Crist RC, Reiner BC, Deisseroth K, Yttri EA, Corder G. PMID: 38746090; PMCID: PMC11092437.

View in: PubMed Mentions: 1
Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation. Sci Adv. 2024 Apr 26; 10(17):eadj9581. Lubejko ST, Livrizzi G, Buczynski SA, Patel J, Yung JC, Yaksh TL, Banghart MR. PMID: 38669335; PMCID: PMC11051679.

View in: PubMed Mentions: 6 Fields:
Sci Science
Translation:Animals Cells
In vivo photopharmacology with light-activated opioid drugs. Neuron. 2023 Dec 20; 111(24):3926-3940.e10. McClain SP, Ma X, Johnson DA, Johnson CA, Layden AE, Yung JC, Lubejko ST, Livrizzi G, He XJ, Zhou J, Chang-Weinberg J, Ventriglia E, Rizzo A, Levinstein M, Gomez JL, Bonaventura J, Michaelides M, Banghart MR. PMID: 37848025; PMCID: PMC11188017.

View in: PubMed Mentions: 4 Fields:
Neu Neurology
Inputs to the locus coeruleus from the periaqueductal gray and rostroventral medulla shape opioid-mediated descending pain modulation. bioRxiv. 2023 Oct 10. Lubejko ST, Livrizzi G, Patel J, Yung JC, Yaksh TL, Banghart MR. PMID: 37873091; PMCID: PMC10592708.

View in: PubMed Mentions:
A Biomimetic C-Terminal Extension Strategy for Photocaging Amidated Neuropeptides. J Am Chem Soc. 2023 09 13; 145(36):19611-19621. Layden AE, Ma X, Johnson CA, He XJ, Buczynski SA, Banghart MR. PMID: 37649440; PMCID: PMC10510324.

View in: PubMed Mentions: 3 Fields:
Che Chemistry
Mu Opioid Receptor-Expressing Neurons in the Dorsal Raphe Nucleus Are Involved in Reward Processing and Affective Behaviors. Biol Psychiatry. 2023 12 01; 94(11):842-851. Welsch L, Colantonio E, Frison M, Johnson DA, McClain SP, Mathis V, Banghart MR, Ben Hamida S, Darcq E, Kieffer BL. PMID: 37285896; PMCID: PMC10850692.

View in: PubMed Mentions: 1 Fields:
Psy Psychiatry Psy Psychophysiology
Translation:Cells
In vivo photopharmacology with a caged mu opioid receptor agonist drives rapid changes in behavior. Nat Methods. 2023 05; 20(5):682-685. Ma X, Johnson DA, He XJ, Layden AE, McClain SP, Yung JC, Rizzo A, Bonaventura J, Banghart MR. PMID: 36973548; PMCID: PMC10569260.

View in: PubMed Mentions: 10 Fields:
Cli Clinical Laboratory Techniques
Translation:Animals
In vivo photopharmacology with light-activated opioid drugs. bioRxiv. 2023 Feb 03. McClain SP, Ma X, Johnson DA, Johnson CA, Layden AE, Yung JC, Lubejko ST, Livrizzi G, Jenny He X, Zhou J, Ventriglia E, Rizzo A, Levinstein M, Gomez JL, Bonaventura J, Michaelides M, Banghart MR. PMID: 36778286; PMCID: PMC9915677.

View in: PubMed Mentions:
The role of endogenous opioid neuropeptides in neurostimulation-driven analgesia. Front Syst Neurosci. 2022; 16:1044686. Lubejko ST, Graham RD, Livrizzi G, Schaefer R, Banghart MR, Creed MC. PMID: 36591324; PMCID: PMC9794630.

View in: PubMed Mentions: 4
Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons. Elife. 2021 11 17; 10. He XJ, Patel J, Weiss CE, Ma X, Bloodgood BL, Banghart MR. PMID: 34787079; PMCID: PMC8716102.

View in: PubMed Mentions: 16 Fields:
Bio Biology
Translation:Animals Cells
Neural basis of opioid-induced respiratory depression and its rescue. Proc Natl Acad Sci U S A. 2021 06 08; 118(23). Liu S, Kim DI, Oh TG, Pao GM, Kim JH, Palmiter RD, Banghart MR, Lee KF, Evans RM, Han S. PMID: 34074761; PMCID: PMC8201770.

View in: PubMed Mentions: 32 Fields:
Sci Science
Translation:Animals Cells
It's lights out for presynaptic terminals. Neuron. 2021 06 02; 109(11):1755-1757. He XJ, Banghart MR. PMID: 34081915.

View in: PubMed Mentions: 1 Fields:
Neu Neurology
Translation:Animals Cells
The light-sensitive dimerizer zapalog reveals distinct modes of immobilization for axonal mitochondria. Nat Cell Biol. 2019 06; 21(6):768-777. Gutnick A, Banghart MR, West ER, Schwarz TL. PMID: 31061466; PMCID: PMC6662610.

View in: PubMed Mentions: 39 Fields:
Cel Cell Biology
Translation:Animals Cells
A Caged Enkephalin Optimized for Simultaneously Probing Mu and Delta Opioid Receptors. ACS Chem Neurosci. 2018 04 18; 9(4):684-690. Banghart MR, He XJ, Sabatini BL. PMID: 29266926; PMCID: PMC5906201.

View in: PubMed Mentions: 23 Fields:
Neu Neurology
Translation:Animals Cells
When complex neuronal structures may not matter. Elife. 2017 02 06; 6. Otopalik AG, Sutton AC, Banghart M, Marder E. PMID: 28165322; PMCID: PMC5323043.

View in: PubMed Mentions: 23 Fields:
Bio Biology
Translation:Animals Cells
Enkephalin Disinhibits Mu Opioid Receptor-Rich Striatal Patches via Delta Opioid Receptors. Neuron. 2015 Dec 16; 88(6):1227-1239. Banghart MR, Neufeld SQ, Wong NC, Sabatini BL. PMID: 26671460; PMCID: PMC4698909.

View in: PubMed Mentions: 57 Fields:
Neu Neurology
Translation:Animals
Spectral evolution of a photochemical protecting group for orthogonal two-color uncaging with visible light. J Am Chem Soc. 2013 Oct 23; 135(42):15948-54. Olson JP, Banghart MR, Sabatini BL, Ellis-Davies GC. PMID: 24117060; PMCID: PMC4097017.

View in: PubMed Mentions: 34 Fields:
Che Chemistry
Translation:Cells
Caged naloxone reveals opioid signaling deactivation kinetics. Mol Pharmacol. 2013 Nov; 84(5):687-95. Banghart MR, Williams JT, Shah RC, Lavis LD, Sabatini BL. PMID: 23960100; PMCID: PMC3807075.

View in: PubMed Mentions: 17 Fields:
Mol Molecular Biology Pha Pharmacology
Translation:Humans Animals Cells
A 1H NMR assay for measuring the photostationary States of photoswitchable ligands. Methods Mol Biol. 2013; 995:107-20. Banghart MR, Trauner D. PMID: 23494375.

View in: PubMed Mentions: 4 Fields:
Mol Molecular Biology
Translation:Humans Cells
Photoactivatable neuropeptides for spatiotemporally precise delivery of opioids in neural tissue. Neuron. 2012 Jan 26; 73(2):249-59. Banghart MR, Sabatini BL. PMID: 22284180; PMCID: PMC3282187.

View in: PubMed Mentions: 51 Fields:
Neu Neurology
Translation:Animals Cells
Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors. Nat Chem. 2012 Jan 10; 4(2):105-11. Tochitsky I, Banghart MR, Mourot A, Yao JZ, Gaub B, Kramer RH, Trauner D. PMID: 22270644; PMCID: PMC4977190.

View in: PubMed Mentions: 60 Fields:
Che Chemistry
Translation:Animals
Tuning photochromic ion channel blockers. ACS Chem Neurosci. 2011 Sep 21; 2(9):536-43. Mourot A, Kienzler MA, Banghart MR, Fehrentz T, Huber FM, Stein M, Kramer RH, Trauner D. PMID: 22860175; PMCID: PMC3401033.

View in: PubMed Mentions: 55 Fields:
Neu Neurology
Translation:Humans Animals Cells
Optogenetic photochemical control of designer K+ channels in mammalian neurons. J Neurophysiol. 2011 Jul; 106(1):488-96. Fortin DL, Dunn TW, Fedorchak A, Allen D, Montpetit R, Banghart MR, Trauner D, Adelman JP, Kramer RH. PMID: 21525363; PMCID: PMC3129715.

View in: PubMed Mentions: 33 Fields:
Neu Neurology Phy Physiology
Translation:Humans Cells
Photo-targeted nanoparticles. Nano Lett. 2010 Jan; 10(1):250-4. Dvir T, Banghart MR, Timko BP, Langer R, Kohane DS. PMID: 19904979; PMCID: PMC2806491.

View in: PubMed Mentions: 32 Fields:
Nan Nanotechnology
Translation:Humans Animals Cells
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery. AAPS J. 2009 Mar; 11(1):167-77. Lester HA, Xiao C, Srinivasan R, Son CD, Miwa J, Pantoja R, Banghart MR, Dougherty DA, Goate AM, Wang JC. PMID: 19280351; PMCID: PMC2664890.

View in: PubMed Mentions: 90 Fields:
Dru Drug Therapy Pha Pharmacology
Translation:Animals Cells
Photochromic blockers of voltage-gated potassium channels. Angew Chem Int Ed Engl. 2009; 48(48):9097-101. Banghart MR, Mourot A, Fortin DL, Yao JZ, Kramer RH, Trauner D. PMID: 19882609; PMCID: PMC4040390.

View in: PubMed Mentions: 48 Fields:
Che Chemistry
Translation:Humans Cells
Photochemical control of endogenous ion channels and cellular excitability. Nat Methods. 2008 Apr; 5(4):331-8. Fortin DL, Banghart MR, Dunn TW, Borges K, Wagenaar DA, Gaudry Q, Karakossian MH, Otis TS, Kristan WB, Trauner D, Kramer RH. PMID: 18311146; PMCID: PMC2760097.

View in: PubMed Mentions: 85 Fields:
Cli Clinical Laboratory Techniques
Translation:Animals Cells
Engineering light-gated ion channels. Biochemistry. 2006 Dec 26; 45(51):15129-41. Banghart MR, Volgraf M, Trauner D. PMID: 17176035.

View in: PubMed Mentions: 31 Fields:
Bio Biochemistry
Translation:Humans Animals Cells
Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. J Neurophysiol. 2006 Nov; 96(5):2792-6. Chambers JJ, Banghart MR, Trauner D, Kramer RH. PMID: 16870840.

View in: PubMed Mentions: 34 Fields:
Neu Neurology Phy Physiology
Translation:Animals Cells
Light-activated ion channels for remote control of neuronal firing. Nat Neurosci. 2004 Dec; 7(12):1381-6. Banghart M, Borges K, Isacoff E, Trauner D, Kramer RH. PMID: 15558062; PMCID: PMC1447674.

View in: PubMed Mentions: 226 Fields:
Neu Neurology
Translation:Animals Cells
Synthesis and in vitro anti-protozoal activity of a series of benzotropolone derivatives incorporating endocyclic hydrazines. Eur J Med Chem. 2003 Nov-Dec; 38(11-12):949-57. Ren H, Grady S, Banghart M, Moulthrop JS, Kendrick H, Yardley V, Croft SL, Moyna G. PMID: 14642327.

View in: PubMed Mentions: 2 Fields:
Che Chemistry
Translation:Animals