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    Michael Whitney

    TitleProject Scientist
    SchoolUniversity of California, San Diego
    DepartmentPharmacology
    Address9500 Gilman Drive #0647
    CA La Jolla 92093
    Phone858-534-5268
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Hingorani DV, Lemieux AJ, Acevedo JR, Glasgow HL, Kedarisetty S, Whitney M, Molinolo AA, Tsien RY, Nguyen QT. Early detection of squamous cell carcinoma in carcinogen induced oral cancer rodent model by ratiometric activatable cell penetrating peptides. Oral Oncol. 2017 Aug; 71:156-162. PMID: 28688684.
        View in: PubMed
      2. Glasgow HL, Whitney M, Gross LA, Friedman B, Adams SR, Crisp JL, Hussain T, Frei AP, Novy K, Wollscheid B, Nguyen QT, Tsien RY. Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization. Proc Natl Acad Sci U S A. 2016 Oct 20. PMID: 27791138.
        View in: PubMed
      3. Adams SR, Yang HC, Savariar EN, Aguilera J, Crisp JL, Jones KA, Whitney M, Lippman SM, Cohen EE, Tsien RY, Advani SJ. Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize. Nat Commun. 2016 Oct 04; 7:13019. PMID: 27698471.
        View in: PubMed
      4. Hussain T, Nguyen LT, Whitney M, Hasselmann J, Nguyen QT. Improved facial nerve identification during parotidectomy with fluorescently labeled peptide. Laryngoscope. 2016 May 12. PMID: 27171862.
        View in: PubMed
      5. Hua N, Baik F, Pham T, Phinikaridou A, Giordano N, Friedman B, Whitney M, Nguyen QT, Tsien RY, Hamilton JA. Identification of High-Risk Plaques by MRI and Fluorescence Imaging in a Rabbit Model of Atherothrombosis. PLoS One. 2015; 10(10):e0139833. PMID: 26448434.
        View in: PubMed
      6. Hussain T, Mastrodimos MB, Raju SC, Glasgow HL, Whitney M, Friedman B, Moore JD, Kleinfeld D, Steinbach P, Messer K, Pu M, Tsien RY, Nguyen QT. Fluorescently Labeled Peptide Increases Identification of Degenerated Facial Nerve Branches during Surgery and Improves Functional Outcome. PLoS One. 2015; 10(3):e0119600. PMID: 25751149.
        View in: PubMed
      7. Raju SC, Hauff SJ, Lemieux AJ, Orosco RK, Gross AM, Nguyen LT, Savariar E, Moss W, Whitney M, Cohen EE, Lippman SM, Tsien RY, Ideker T, Advani SJ, Nguyen QT. Combined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma. Oral Oncol. 2015 May; 51(5):470-5. PMID: 25735654.
        View in: PubMed
      8. Hauff SJ, Raju SC, Orosco RK, Gross AM, Diaz-Perez JA, Savariar E, Nashi N, Hasselman J, Whitney M, Myers JN, Lippman SM, Tsien RY, Ideker T, Nguyen QT. Matrix-metalloproteinases in head and neck carcinoma-cancer genome atlas analysis and fluorescence imaging in mice. Otolaryngol Head Neck Surg. 2014 Oct; 151(4):612-8. PMID: 25091190.
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      9. Levin RA, Felsen CN, Yang J, Lin JY, Whitney M, Nguyen QT, Tsien RY. An optimized triple modality reporter for quantitative in vivo tumor imaging and therapy evaluation. PLoS One. 2014; 9(5):e97415. PMID: 24816650.
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      10. Crisp JL, Savariar EN, Glasgow HL, Ellies LG, Whitney M, Tsien RY. Dual Targeting of Integrin avß3 and Matrix Metalloproteinase-2 for Optical Imaging of Tumors and Chemotherapeutic Delivery. Mol Cancer Ther. 2014 Jun; 13(6):1514-25. PMID: 24737028.
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      11. Davalos D, Baeten KM, Whitney M, Mullins ES, Friedman B, Olson ES, Ryu JK, Smirnoff DS, Petersen MA, Bedard C, Degen JL, Tsien RY, Akassoglou K. Early detection of thrombin activity in neuroinflammatory disease. Ann Neurol. 2014 Feb; 75(2):303-8. PMID: 24740641.
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      12. Felsen CN, Savariar EN, Whitney M, Tsien RY. Detection and monitoring of localized matrix metalloproteinase upregulation in a murine model of asthma. Am J Physiol Lung Cell Mol Physiol. 2014 Apr; 306(8):L764-74. PMID: 24508733.
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      13. Whitney M, Savariar EN, Friedman B, Levin RA, Crisp JL, Glasgow HL, Lefkowitz R, Adams SR, Steinbach P, Nashi N, Nguyen QT, Tsien RY. Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation. Angew Chem Int Ed Engl. 2013 Jan 2; 52(1):325-30. PMID: 23080482.
        View in: PubMed
      14. Chen B, Friedman B, Whitney M, Winkle JA, Lei IF, Olson ES, Cheng Q, Pereira B, Zhao L, Tsien RY, Lyden PD. Thrombin activity associated with neuronal damage during acute focal ischemia. J Neurosci. 2012 May 30; 32(22):7622-31. PMID: 22649241.
        View in: PubMed
      15. Olson ES, Whitney M, Friedman B, Aguilera TA, Crisp JL, Baik FM, Jiang T, Baird SM, Tsimikas S, Tsien RY, Nguyen QT. In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol (Camb). 2012 Jun; 4(6):595-605. PMID: 22534729.
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      16. Wu AP, Whitney M, Crisp JL, Friedman B, Tsien RY, Nguyen QT. Improved facial nerve identification with novel fluorescently labeled probe. Laryngoscope. 2011 Apr; 121(4):805-10. PMID: 21328585.
        View in: PubMed
      17. Whitney M, Crisp JL, Nguyen LT, Friedman B, Gross LA, Steinbach P, Tsien RY, Nguyen QT. Fluorescent peptides highlight peripheral nerves during surgery in mice. Nat Biotechnol. 2011 Apr; 29(4):352-6. PMID: 21297616.
        View in: PubMed
      18. Shu X, Lev-Ram V, Olson ES, Aguilera TA, Jiang T, Whitney M, Crisp JL, Steinbach P, Deerinck T, Ellisman MH, Ellies LG, Nguyen QT, Tsien RY. Spiers Memorial Lecture. Breeding and building molecular spies. Faraday Discuss. 2011; 149:9; discussion 63-77. PMID: 21413170.
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      19. Jarecki J, Chen X, Bernardino A, Coovert DD, Whitney M, Burghes A, Stack J, Pollok BA. Diverse small-molecule modulators of SMN expression found by high-throughput compound screening: early leads towards a therapeutic for spinal muscular atrophy. Hum Mol Genet. 2005 Jul 15; 14(14):2003-18. PMID: 15944201.
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      20. Zeh K, Sanders P, Londo P, Crute JJ, Pollok BA, Whitney M. Gain-of-function somatic cell lines for drug discovery applications generated by homologous recombination. Assay Drug Dev Technol. 2003 Dec; 1(6):755-65. PMID: 15090222.
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      21. Andreassi C, Jarecki J, Zhou J, Coovert DD, Monani UR, Chen X, Whitney M, Pollok B, Zhang M, Androphy E, Burghes AH. Aclarubicin treatment restores SMN levels to cells derived from type I spinal muscular atrophy patients. Hum Mol Genet. 2001 Nov 15; 10(24):2841-9. PMID: 11734549.
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      22. Waxman L, Whitney M, Pollok BA, Kuo LC, Darke PL. Host cell factor requirement for hepatitis C virus enzyme maturation. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13931-5. PMID: 11707594.
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      23. Stack JH, Whitney M, Rodems SM, Pollok BA. A ubiquitin-based tagging system for controlled modulation of protein stability. Nat Biotechnol. 2000 Dec; 18(12):1298-302. PMID: 11101811.
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      24. Whitney M, Rockenstein E, Cantin G, Knapp T, Zlokarnik G, Sanders P, Durick K, Craig FF, Negulescu PA. A genome-wide functional assay of signal transduction in living mammalian cells. Nat Biotechnol. 1998 Dec; 16(13):1329-33. PMID: 9853613.
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      25. Li W, Llopis J, Whitney M, Zlokarnik G, Tsien RY. Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression. Nature. 1998 Apr 30; 392(6679):936-41. PMID: 9582076.
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      26. Zlokarnik G, Negulescu PA, Knapp TE, Mere L, Burres N, Feng L, Whitney M, Roemer K, Tsien RY. Quantitation of transcription and clonal selection of single living cells with beta-lactamase as reporter. Science. 1998 Jan 2; 279(5347):84-8. PMID: 9417030.
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      27. Whitney M, Royle G, Low MJ, Kelly MA, Axthelm MK, Reifsteck C, Olson S, Braun RE, Heinrich MC, Rathbun RK, Bagby GC, Grompe M. Germ cell defects and hematopoietic hypersensitivity to gamma-interferon in mice with a targeted disruption of the Fanconi anemia C gene. Blood. 1996 Jul 1; 88(1):49-58. PMID: 8704201.
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      28. Cassill JA, Whitney M, Joazeiro CA, Becker A, Zuker CS. Isolation of Drosophila genes encoding G protein-coupled receptor kinases. Proc Natl Acad Sci U S A. 1991 Dec 15; 88(24):11067-70. PMID: 1662381.
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      29. LeVine H, Smith DP, Whitney M, Malicki DM, Dolph PJ, Smith GF, Burkhart W, Zuker CS. Isolation of a novel visual-system-specific arrestin: an in vivo substrate for light-dependent phosphorylation. Mech Dev. 1990 Dec; 33(1):19-25. PMID: 2129011.
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