Sign in to edit your profile (add interests, mentoring, photo, etc.)

    Philip Gordts

    TitleAssistant Researcher
    SchoolUniversity of California, San Diego
    DepartmentMedicine
    Address9500 Gilman Drive #0687
    CA La Jolla 92093
    Phone858-246-0994
    vCardDownload vCard

      Collapse Biography 
      Collapse Awards and Honors
      European Lipoprotein Club2007 - 2008Young Investigator Award
      International Atherosclerosis Society2006Young Investigator Award
      European Union2011 - 2015Marie Curie International outgoing fellowship
      University of California, San Diego2014UCSD Chancellor’s Award for Outstanding Postdoctoral Scholar
      American Heart Association2015 - 2017Beginning Grant In-Aid Award
      Journal of Lipid Research 2016Junior Investigator Award

      Collapse ORNG Applications 
      Collapse Websites

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Moriarty PM, Varvel SA, Gordts PL, McConnell JP, Tsimikas S. Lipoprotein(a) Mass Levels Increase Significantly According to APOE Genotype: An Analysis of 431?239 Patients. Arterioscler Thromb Vasc Biol. 2017 Jan 05. PMID: 28062489.
        View in: PubMed
      2. Gordts PL, Nock R, Son NH, Ramms B, Lew I, Gonzales JC, Thacker BE, Basu D, Lee RG, Mullick AE, Graham MJ, Goldberg IJ, Crooke RM, Witztum JL, Esko JD. ApoC-III inhibits clearance of triglyceride-rich lipoproteins through LDL family receptors. J Clin Invest. 2016 Aug 1; 126(8):2855-2866. PMID: 27400128.
        View in: PubMed
      3. Khalid O, Vera MU, Gordts PL, Ellinwood NM, Schwartz PH, Dickson PI, Esko JD, Wang RY. Immune-Mediated Inflammation May Contribute to the Pathogenesis of Cardiovascular Disease in Mucopolysaccharidosis Type I. PLoS One. 2016; 11(3):e0150850. PMID: 26986213.
        View in: PubMed
      4. Ramms B, Gordts PL. Dietary nitrate struggles in atherosclerosis. Atherosclerosis. 2016 Feb; 245:71-3. PMID: 26708286.
        View in: PubMed
      5. Weiss RJ, Gordts PL, Le D, Xu D, Esko JD, Tor Y. Small molecule antagonists of cell-surface heparan sulfate and heparin-protein interactions. Chem Sci. 2015 Oct 01; 6(10):5984-5993. PMID: 28133533.
        View in: PubMed
      6. Akizu N, Cantagrel V, Zaki MS, Al-Gazali L, Wang X, Rosti RO, Dikoglu E, Gelot AB, Rosti B, Vaux KK, Scott EM, Silhavy JL, Schroth J, Copeland B, Schaffer AE, Gordts PL, Esko JD, Buschman MD, Field SJ, Napolitano G, Abdel-Salam GM, Ozgul RK, Sagiroglu MS, Azam M, Ismail S, Aglan M, Selim L, Mahmoud IG, Abdel-Hadi S, Badawy AE, Sadek AA, Mojahedi F, Kayserili H, Masri A, Bastaki L, Temtamy S, Müller U, Desguerre I, Casanova JL, Dursun A, Gunel M, Gabriel SB, de Lonlay P, Gleeson JG. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015 May; 47(5):528-34. PMID: 25848753.
        View in: PubMed
      7. Berbée JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development. Nat Commun. 2015; 6:6356. PMID: 25754609.
        View in: PubMed
      8. Mooij HL, Bernelot Moens SJ, Gordts PL, Stanford KI, Foley EM, van den Boogert MA, Witjes JJ, Hassing HC, Tanck MW, van de Sande MA, Levels JH, Kastelein JJ, Stroes ES, Dallinga-Thie GM, Esko JD, Nieuwdorp M. Ext1 heterozygosity causes a modest effect on postprandial lipid clearance in humans. J Lipid Res. 2015 Mar; 56(3):665-73. PMID: 25568062.
        View in: PubMed
      9. Gordts PL, Esko JD. Heparan sulfate proteoglycans fine-tune macrophage inflammation via IFN-ß. Cytokine. 2015 Mar; 72(1):118-9. PMID: 25573804.
        View in: PubMed
      10. Gordts PL, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD. Reducing Macrophage Proteoglycan Sulfation Increases Atherosclerosis and Obesity through Enhanced Type I Interferon Signaling. Cell Metab. 2014 Nov 4; 20(5):813-26. PMID: 25440058.
        View in: PubMed
      11. Foley EM, Gordts PL, Stanford KI, Gonzales JC, Lawrence R, Stoddard N, Esko JD. Hepatic remnant lipoprotein clearance by heparan sulfate proteoglycans and low-density lipoprotein receptors depend on dietary conditions in mice. Arterioscler Thromb Vasc Biol. 2013 Sep; 33(9):2065-74. PMID: 23846497.
        View in: PubMed
      12. Gonzales JC, Gordts PL, Foley EM, Esko JD. Apolipoproteins E and AV mediate lipoprotein clearance by hepatic proteoglycans. J Clin Invest. 2013 Jun 3; 123(6):2742-51. PMID: 23676495.
        View in: PubMed
      13. Lamanna WC, Lawrence R, Sarrazin S, Lameda-Diaz C, Gordts PL, Moremen KW, Esko JD. A genetic model of substrate reduction therapy for mucopolysaccharidosis. J Biol Chem. 2012 Oct 19; 287(43):36283-90. PMID: 22952226.
        View in: PubMed
      14. Christoffersen C, Benn M, Christensen PM, Gordts PL, Roebroek AJ, Frikke-Schmidt R, Tybjaerg-Hansen A, Dahlbäck B, Nielsen LB. The plasma concentration of HDL-associated apoM is influenced by LDL receptor-mediated clearance of apoB-containing particles. J Lipid Res. 2012 Oct; 53(10):2198-204. PMID: 22826357.
        View in: PubMed
      15. Gordts PL, Bartelt A, Nilsson SK, Annaert W, Christoffersen C, Nielsen LB, Heeren J, Roebroek AJ. Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice. PLoS One. 2012; 7(6):e38330. PMID: 22701627.
        View in: PubMed
      16. Deng Y, Foley EM, Gonzales JC, Gordts PL, Li Y, Esko JD. Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance. Hepatology. 2012 Jan; 55(1):277-86. PMID: 21898481.
        View in: PubMed
      17. Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, Eychmüller A, Gordts PL, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J. Brown adipose tissue activity controls triglyceride clearance. Nat Med. 2011 Feb; 17(2):200-5. PMID: 21258337.
        View in: PubMed
      18. Roebroek AJ, Gordts PL, Reekmans S. Knock-in approaches. Methods Mol Biol. 2011; 693:257-75. PMID: 21080285.
        View in: PubMed
      19. Roebroek AJ, Gordts PL, Reekmans S. Generation of a series of knock-in alleles using RMCE in ES cells. Methods Mol Biol. 2011; 693:277-81. PMID: 21080286.
        View in: PubMed
      20. Christoffersen C, Pedersen TX, Gordts PL, Roebroek AJ, Dahlbäck B, Nielsen LB. Opposing effects of apolipoprotein m on catabolism of apolipoprotein B-containing lipoproteins and atherosclerosis. Circ Res. 2010 May 28; 106(10):1624-34. PMID: 20360257.
        View in: PubMed
      21. Reekmans SM, Pflanzner T, Gordts PL, Isbert S, Zimmermann P, Annaert W, Weggen S, Roebroek AJ, Pietrzik CU. Inactivation of the proximal NPXY motif impairs early steps in LRP1 biosynthesis. Cell Mol Life Sci. 2010 Jan; 67(1):135-45. PMID: 19856143.
        View in: PubMed
      22. Gordts PL, Reekmans S, Lauwers A, Van Dongen A, Verbeek L, Roebroek AJ. Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Sep; 29(9):1258-64. PMID: 19667105.
        View in: PubMed
      Philip's Networks
      Concepts
      Derived automatically from this person's publications.
      _
      Co-Authors
      People in Profiles who have published with this person.
      _
      Similar People
      People who share similar concepts with this person.
      _
      Same Department
      Physical Neighbors
      People whose addresses are nearby this person.
      _
      Back to TOP