Dzung Le

Title(s)Clinical Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Glycan Modulation of Inflammatory Responses
    NIH P01HL107150Jul 1, 2011 - May 31, 2018
    Role: Co-Investigator
    Genetic Modulation of Blood and Vascular Glycosylation
    NIH P01HL057345Sep 30, 1997 - Dec 31, 2013
    Role: Co-Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Novel Approach to Improve the Identification of the Bleeding Phenotype in Noonan Syndrome and Related RASopathies. J Pediatr. 2023 06; 257:113323. Bruno L, Lenberg J, Le D, Dimmock D, Thornburg CD, Briggs B. PMID: 36646249.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    2. A Novel Hypomorphic Apex1 Mouse Model Implicates Apurinic/Apyrimidinic Endonuclease 1 in Oxidative DNA Damage Repair in Gastric Epithelial Cells. Antioxid Redox Signal. 2023 01; 38(1-3):183-197. Rios-Covian D, Butcher LD, Ablack AL, den Hartog G, Matsubara MT, Ly H, Oates AW, Xu G, Fisch KM, Ahrens ET, Toden S, Brown CC, Kim K, Le D, Eckmann L, Dhar B, Izumi T, Ernst PB, Crowe SE. PMID: 35754343; PMCID: PMC10039277.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. Endothelial Heparan Sulfate Mediates Hepatic Neutrophil Trafficking and Injury during Staphylococcus aureus Sepsis. mBio. 2021 10 26; 12(5):e0118121. Golden GJ, Toledo AG, Marki A, Sorrentino JT, Morris C, Riley RJ, Spliid C, Chen Q, Cornax I, Lewis NE, Varki N, Le D, Malmström J, Karlsson C, Ley K, Nizet V, Esko JD. PMID: 34544271; PMCID: PMC8546592.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    4. The Evaluation of Hematologic Screening and Perioperative Management in Patients with Noonan Syndrome: A Retrospective Chart Review. J Pediatr. 2020 05; 220:154-158.e6. Briggs B, Savla D, Ramchandar N, Dimmock D, Le D, Thornburg CD. PMID: 32111381.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    5. Small molecule antagonists of cell-surface heparan sulfate and heparin-protein interactions. Chem Sci. 2015 Oct 01; 6(10):5984-5993. Weiss RJ, Gordts PL, Le D, Xu D, Esko JD, Tor Y. PMID: 28133533; PMCID: PMC5267326.
      View in: PubMed   Mentions: 12  
    6. A phenotype survey of 36 mutant mouse strains with gene-targeted defects in glycosyltransferases or glycan-binding proteins. Glycobiology. 2013 Mar; 23(3):363-80. Orr SL, Le D, Long JM, Sobieszczuk P, Ma B, Tian H, Fang X, Paulson JC, Marth JD, Varki N. PMID: 23118208; PMCID: PMC3605971.
      View in: PubMed   Mentions: 29     Fields:    Translation:Animals
    7. Systemic mastocytosis in association with chronic lymphocytic leukemia and plasma cell myeloma. Int J Clin Exp Pathol. 2010 Apr 23; 3(4):448-57. Du S, Rashidi HH, Le DT, Kipps TJ, Broome HE, Wang HY. PMID: 20490336; PMCID: PMC2872752.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    8. In vitro sonothrombolysis with duplex ultrasound: first results using a simplified model. Cerebrovasc Dis. 2009; 28(4):365-70. Holscher T, Raman R, Ernström K, Parrish J, Le DT, Lyden PD, Mattrey RF. PMID: 19641311.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    9. The Ashwell receptor mitigates the lethal coagulopathy of sepsis. Nat Med. 2008 Jun; 14(6):648-55. Grewal PK, Uchiyama S, Ditto D, Varki N, Le DT, Nizet V, Marth JD. PMID: 18488037; PMCID: PMC2853759.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    10. Initiation of protein O glycosylation by the polypeptide GalNAcT-1 in vascular biology and humoral immunity. Mol Cell Biol. 2007 Dec; 27(24):8783-96. Tenno M, Ohtsubo K, Hagen FK, Ditto D, Zarbock A, Schaerli P, von Andrian UH, Ley K, Le D, Tabak LA, Marth JD. PMID: 17923703; PMCID: PMC2169402.
      View in: PubMed   Mentions: 59     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    11. Selectin-mucin interactions as a probable molecular explanation for the association of Trousseau syndrome with mucinous adenocarcinomas. J Clin Invest. 2003 Sep; 112(6):853-62. Wahrenbrock M, Borsig L, Le D, Varki N, Varki A. PMID: 12975470; PMCID: PMC193671.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansAnimalsCells
    12. Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligands. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):10042-7. Ellies LG, Ditto D, Levy GG, Wahrenbrock M, Ginsburg D, Varki A, Le DT, Marth JD. PMID: 12097641; PMCID: PMC126621.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    13. Modeling human congenital disorder of glycosylation type IIa in the mouse: conservation of asparagine-linked glycan-dependent functions in mammalian physiology and insights into disease pathogenesis. Glycobiology. 2001 Dec; 11(12):1051-70. Wang Y, Tan J, Sutton-Smith M, Ditto D, Panico M, Campbell RM, Varki NM, Long JM, Jaeken J, Levinson SR, Wynshaw-Boris A, Morris HR, Le D, Dell A, Schachter H, Marth JD. PMID: 11805078.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    14. Decrease in the plasma von Willebrand factor concentration following glucose ingestion: the role of insulin sensitivity. Metabolism. 2001 Dec; 50(12):1452-6. von Känel R, Nelesen RA, Le DT, Ziegler MG, Dimsdale JE. PMID: 11735092.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The hypercoagulable state in sleep apnea is related to comorbid hypertension. J Hypertens. 2001 Aug; 19(8):1445-51. von Känel R, Le DT, Nelesen RA, Mills PJ, Ancoli-Israel S, Dimsdale JE. PMID: 11518853.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    16. Quantitative effects of nefiracetam on spatial learning of rats after cerebral embolism. J Stroke Cerebrovasc Dis. 2001 May-Jun; 10(3):99-105. Le DT, Shin C, Jackson-Friedman C, Lyden PD. PMID: 17903808.
      View in: PubMed   Mentions: 1     Fields:    
    17. A novel clotting assay for quantitation of plasma prothrombin (factor II) using Echis multisquamatus venom. Am J Clin Pathol. 1999 Nov; 112(5):705-11. Petrovan RJ, Rapaport SI, Le DT. PMID: 10549258.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    18. Hemostatic factors in rabbit limb lymph: relationship to mechanisms regulating extravascular coagulation. Am J Physiol. 1998 03; 274(3):H769-76. Le DT, Borgs P, Toneff TW, Witte MH, Rapaport SI. PMID: 9530187.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    19. A Protac-based screening test for activated protein C-resistant factor Va and other defects of the protein C anticoagulant pathway. Blood Coagul Fibrinolysis. 1997 Sep; 8(6):327-35. Gable PS, Le DT, McGehee W, Rapaport SI. PMID: 9351522.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    20. Correction of excessive anticoagulation with low-dose oral vitamin K1. Ann Intern Med. 1997 Jun 15; 126(12):959-62. Weibert RT, Le DT, Kayser SR, Rapaport SI. PMID: 9182473.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    21. Protac, a commercially available protein C activator from the venom of Agkistrodon contortrix contortrix, can activate factor V and factor VIII. Thromb Res. 1997 Apr 01; 86(1):79-84. Gable PS, Le DT, Rapaport SI. PMID: 9172290.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    22. Reliability of a modified tissue factor-dependent factor V assay for activated protein C resistant factor Va using a calcium-containing thromboplastin. Thromb Haemost. 1997 Mar; 77(3):481-5. Le DT, Donnelly KJ, Wu N, Sevilla BK, Rapaport SI. PMID: 9065998.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    23. A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8606-11. Olee T, Pierangeli SS, Handley HH, Le DT, Wei X, Lai CJ, En J, Novotny W, Harris EN, Woods VL, Chen PP. PMID: 8710918; PMCID: PMC38720.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    24. Use of a generally applicable tissue factor--dependent factor V assay to detect activated protein C-resistant factor Va in patients receiving warfarin and in patients with a lupus anticoagulant. Blood. 1995 Apr 01; 85(7):1704-11. Le DT, Griffin JH, Greengard JS, Mujumdar V, Rapaport SI. PMID: 7703480.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    25. Studies of the mechanism for enhanced cell surface factor VIIa/tissue factor activation of factor X on fibroblast monolayers after their exposure to N-ethylmaleimide. Thromb Haemost. 1994 Dec; 72(6):848-55. Le DT, Rapaport SI, Rao LV. PMID: 7740453.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    26. The international normalized ratio (INR) for monitoring warfarin therapy: reliability and relation to other monitoring methods. Ann Intern Med. 1994 Apr 01; 120(7):552-8. Le DT, Weibert RT, Sevilla BK, Donnelly KJ, Rapaport SI. PMID: 8116992.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    27. Relations between factor VIIa binding and expression of factor VIIa/tissue factor catalytic activity on cell surfaces. J Biol Chem. 1992 Aug 05; 267(22):15447-54. Le DT, Rapaport SI, Rao LV. PMID: 1639786.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
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