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    Yitzhak Tor

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentChemistry and Biochemistry
    Address9500 Gilman Drive #0358
    CA La Jolla 92093
    Phone858-534-6401
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      Collapse Research 
      Collapse Research Activities and Funding
      Cellular uptake of glycoside-based transporters
      NIH/NIGMS R01GM077471May 1, 2007 - Feb 28, 2011
      Role: Principal Investigator
      Fluorescent Nucleosides and Oligonucleotides
      NIH/NIGMS R01GM069773Jan 1, 2004 - Apr 30, 2021
      Role: Principal Investigator
      Novel Approaches to the Discovery of Anti-HIV Agents
      NIH/NIAID R01AI047673May 1, 2000 - Apr 30, 2009
      Role: Principal Investigator
      METAL CONTAINING DNA--SYNTHESIS AND PROPERTIES
      NIH/NIGMS R01GM058447Feb 1, 1999 - Jul 31, 2003
      Role: Principal Investigator
      MODIFIED AMINOGLYCOSIDE AMTIBIOTICS AS ANTIHIV DRUGS
      NIH/NIAID R21AI040315Sep 30, 1997 - Sep 29, 1998
      Role: Principal Investigator
      Peptidomimetic Opioids, Synthesis, Structure &Biology
      NIH/NIDA R01DA005539Jul 1, 1990 - Aug 31, 2007
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Rovira AR, Tor Y. Synthesis of unique spirocyclic orthoester-type derivatives of isothiazolo[4,3-d]pyrimidine nucleosides. J Antibiot (Tokyo). 2017 Jul 26. PMID: 28743975.
        View in: PubMed
      2. Weiss RJ, Esko JD, Tor Y. Targeting heparin and heparan sulfate protein interactions. Org Biomol Chem. 2017 Jul 21; 15(27):5656-5668. PMID: 28653068.
        View in: PubMed
      3. Rovira AR, Fin A, Tor Y. Expanding a fluorescent RNA alphabet: synthesis, photophysics and utility of isothiazole-derived purine nucleoside surrogates. Chem Sci. 2017 Apr 01; 8(4):2983-2993. PMID: 28451365.
        View in: PubMed
      4. Kilin V, Gavvala K, Barthes NP, Michel BY, Shin D, Boudier C, Mauffret O, Yashchuk V, Mousli M, Ruff M, Granger F, Eiler S, Bronner C, Tor Y, Burger A, Mély Y. Dynamics of methylated cytosine flipping by UHRF1. J Am Chem Soc. 2017 Jan 23. PMID: 28112929.
        View in: PubMed
      5. Li Y, Fin A, McCoy L, Tor Y. Polymerase-Mediated Site-Specific Incorporation of a Synthetic Fluorescent Isomorphic G Surrogate into RNA. Angew Chem Int Ed Engl. 2016 Dec 21. PMID: 28000329.
        View in: PubMed
      6. Hopkins PA, McCoy LS, Tor Y. Enzymatic incorporation and utilization of an emissive 6-azauridine. Org Biomol Chem. 2016 Dec 16. PMID: 27981333.
        View in: PubMed
      7. Sganappa A, Wexselblatt E, Bellucci MC, Esko J, Tedeschi G, Tor Y, Volonterio A. Dendrimeric Guanidinoneomycin for Cellular Delivery of Biomacromolecules. Chembiochem. 2016 Nov 2. PMID: 27806190.
        View in: PubMed
      8. Freeman NS, Moore CE, Wilhelmsson LM, Tor Y. Chromophoric Nucleoside Analogues: Synthesis and Characterization of 6-Aminouracil-Based Nucleodyes. J Org Chem. 2016 Jun 3; 81(11):4530-9. PMID: 27128151.
        View in: PubMed
      9. Hamill KM, McCoy LS, Wexselblatt E, Esko JD, Tor Y. Polymyxins Facilitate Entry into Mammalian Cells. Chem Sci. 2016 Aug 01; 7(8):5059-5068. PMID: 28044098.
        View in: PubMed
      10. Kong B, Joshi T, Belousoff MJ, Tor Y, Graham B, Spiccia L. Neomycin B-cyclen conjugates and their Zn(II) complexes as RNA-binding agents. J Inorg Biochem. 2016 Sep; 162:334-342. PMID: 26786595.
        View in: PubMed
      11. Rovira AR, Fin A, Tor Y. Chemical Mutagenesis of an Emissive RNA Alphabet. J Am Chem Soc. 2015 Nov 25; 137(46):14602-5. PMID: 26523462.
        View in: PubMed
      12. Weiss RJ, Gordts PL, Le D, Xu D, Esko JD, Tor Y. Small molecule antagonists of cell-surface heparan sulfate and heparin-protein interactions. Chem Sci. 2015 Oct 01; 6(10):5984-5993. PMID: 28133533.
        View in: PubMed
      13. Mizrahi RA, Shin D, Sinkeldam RW, Phelps KJ, Fin A, Tantillo DJ, Tor Y, Beal PA. A Fluorescent Adenosine Analogue as a Substrate for an A-to-I RNA Editing Enzyme. Angew Chem Int Ed Engl. 2015 Jul 20; 54(30):8713-6. PMID: 26095193.
        View in: PubMed
      14. Wexselblatt E, Esko JD, Tor Y. GNeosomes: Highly Lysosomotropic Nanoassemblies for Lysosomal Delivery. ACS Nano. 2015 Apr 28; 9(4):3961-8. PMID: 25831231.
        View in: PubMed
      15. Sholokh M, Sharma R, Shin D, Das R, Zaporozhets OA, Tor Y, Mély Y. Conquering 2-Aminopurine's Deficiencies: Highly Emissive Isomorphic Guanosine Surrogate Faithfully Monitors Guanosine Conformation and Dynamics in DNA. J Am Chem Soc. 2015 Mar 11; 137(9):3185-8. PMID: 25714036.
        View in: PubMed
      16. Rios AC, Yu HT, Tor Y. Hydrolytic Fitness of N-glycosyl Bonds: Comparing the Deglycosylation Kinetics of Modified, Alternative and Native Nucleosides. J Phys Org Chem. 2015 Mar; 28(3):173-180. PMID: 25750482.
        View in: PubMed
      17. Shin D, Lönn P, Dowdy SF, Tor Y. Cellular activity of siRNA oligonucleotides containing synthetic isomorphic nucleoside surrogates. Chem Commun (Camb). 2015 Jan 15; 51(9):1662-5. PMID: 25500944.
        View in: PubMed
      18. McCoy LS, Shin D, Tor Y. Isomorphic emissive GTP surrogate facilitates initiation and elongation of in vitro transcription reactions. J Am Chem Soc. 2014 Oct 29; 136(43):15176-84. PMID: 25255464.
        View in: PubMed
      19. Hopkins PA, Sinkeldam RW, Tor Y. Visibly emissive and responsive extended 6-aza-uridines. Org Lett. 2014 Oct 17; 16(20):5290-3. PMID: 25285451.
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      20. Fair RJ, Tor Y. Antibiotics and bacterial resistance in the 21st century. Perspect Medicin Chem. 2014; 6:25-64. PMID: 25232278.
        View in: PubMed
      21. Fair RJ, McCoy LS, Hensler ME, Aguilar B, Nizet V, Tor Y. Singly Modified Amikacin and Tobramycin Derivatives Show Increased rRNA A-Site Binding and Higher Potency against Resistant Bacteria. ChemMedChem. 2014 Sep; 9(9):2164-71. PMID: 25055981.
        View in: PubMed
      22. Wexselblatt E, Esko JD, Tor Y. On guanidinium and cellular uptake. J Org Chem. 2014 Aug 1; 79(15):6766-74. PMID: 25019333.
        View in: PubMed
      23. Müller UF, Tor Y. Citric Acid and the RNA world. Angew Chem Int Ed Engl. 2014 May 19; 53(21):5245-7. PMID: 24828228.
        View in: PubMed
      24. Inoue M, Wexselblatt E, Esko JD, Tor Y. Macromolecular uptake of alkyl-chain-modified guanidinoglycoside molecular transporters. Chembiochem. 2014 Mar 21; 15(5):676-80. PMID: 24677320.
        View in: PubMed
      25. Lane RS, Jones R, Sinkeldam RW, Tor Y, Magennis SW. Two-photon-induced fluorescence of isomorphic nucleobase analogs. Chemphyschem. 2014 Apr 4; 15(5):867-71. PMID: 24604669.
        View in: PubMed
      26. Sinkeldam RW, McCoy LS, Shin D, Tor Y. Enzymatic interconversion of isomorphic fluorescent nucleosides: adenosine deaminase transforms an adenosine analogue into an inosine analogue. Angew Chem Int Ed Engl. 2013 Dec 23; 52(52):14026-30. PMID: 24288262.
        View in: PubMed
      27. Saenz R, Messmer B, Futalan D, Tor Y, Larsson M, Daniels G, Esener S, Messmer D. Activity of the HMGB1-derived immunostimulatory peptide Hp91 resides in the helical C-terminal portion and is enhanced by dimerization. Mol Immunol. 2014 Feb; 57(2):191-9. PMID: 24172222.
        View in: PubMed
      28. McCoy LS, Roberts KD, Nation RL, Thompson PE, Velkov T, Li J, Tor Y. Polymyxins and analogues bind to ribosomal RNA and interfere with eukaryotic translation in vitro. Chembiochem. 2013 Nov 4; 14(16):2083-6. PMID: 24105917.
        View in: PubMed
      29. Peters JP, Yelgaonkar SP, Srivatsan SG, Tor Y, James Maher L. Mechanical properties of DNA-like polymers. Nucleic Acids Res. 2013 Dec 1; 41(22):10593-604. PMID: 24013560.
        View in: PubMed
      30. Noé MS, Sinkeldam RW, Tor Y. Oligodeoxynucleotides containing multiple thiophene-modified isomorphic fluorescent nucleosides. J Org Chem. 2013 Aug 16; 78(16):8123-8. PMID: 23859712.
        View in: PubMed
      31. Liu W, Shin D, Tor Y, Cooperman BS. Monitoring translation with modified mRNAs strategically labeled with isomorphic fluorescent guanosine mimetics. ACS Chem Biol. 2013 Sep 20; 8(9):2017-23. PMID: 23865809.
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      32. Rios AC, Tor Y. On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution. Isr J Chem. 2013 Jun; 53(6-7):469-483. PMID: 25284884.
        View in: PubMed
      33. Inoue M, Tong W, Esko JD, Tor Y. Aggregation-mediated macromolecular uptake by a molecular transporter. ACS Chem Biol. 2013 Jul 19; 8(7):1383-8. PMID: 23621420.
        View in: PubMed
      34. Frolov L, Dix A, Tor Y, Tesler AB, Chaikin Y, Vaskevich A, Rubinstein I. Direct observation of aminoglycoside-RNA binding by localized surface plasmon resonance spectroscopy. Anal Chem. 2013 Feb 19; 85(4):2200-7. PMID: 23368968.
        View in: PubMed
      35. Rios AC, Tor Y. Refining the genetic alphabet: a late-period selection pressure? Astrobiology. 2012 Sep; 12(9):884-91. PMID: 22984873.
        View in: PubMed
      36. Sinkeldam RW, Hopkins PA, Tor Y. Modified 6-aza uridines: highly emissive pH-sensitive fluorescent nucleosides. Chemphyschem. 2012 Oct 8; 13(14):3350-6. PMID: 22777983.
        View in: PubMed
      37. Noé MS, Ríos AC, Tor Y. Design, synthesis, and spectroscopic properties of extended and fused pyrrolo-dC and pyrrolo-C analogs. Org Lett. 2012 Jun 15; 14(12):3150-3. PMID: 22646728.
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      38. Fair RJ, Hensler ME, Thienphrapa W, Dam QN, Nizet V, Tor Y. Selectively guanidinylated aminoglycosides as antibiotics. ChemMedChem. 2012 Jul; 7(7):1237-44. PMID: 22639134.
        View in: PubMed
      39. Wanunu M, Bhattacharya S, Xie Y, Tor Y, Aksimentiev A, Drndic M. Nanopore analysis of individual RNA/antibiotic complexes. ACS Nano. 2011 Dec 27; 5(12):9345-53. PMID: 22067050.
        View in: PubMed
      40. Shin D, Sinkeldam RW, Tor Y. Emissive RNA alphabet. J Am Chem Soc. 2011 Sep 28; 133(38):14912-5. PMID: 21866967.
        View in: PubMed
      41. Sinkeldam RW, Marcus P, Uchenik D, Tor Y. Multisensing emissive pyrimidine. Chemphyschem. 2011 Aug 22; 12(12):2260-5. PMID: 21698743.
        View in: PubMed
      42. Shukla GC, Haque F, Tor Y, Wilhelmsson LM, Toulmé JJ, Isambert H, Guo P, Rossi JJ, Tenenbaum SA, Shapiro BA. A boost for the emerging field of RNA nanotechnology. ACS Nano. 2011 May 24; 5(5):3405-18. PMID: 21604810.
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      43. Shin D, Tor Y. Bifacial nucleoside as a surrogate for both T and A in duplex DNA. J Am Chem Soc. 2011 May 11; 133(18):6926-9. PMID: 21495708.
        View in: PubMed
      44. Sinkeldam RW, Wheat AJ, Boyaci H, Tor Y. Emissive nucleosides as molecular rotors. Chemphyschem. 2011 Feb 25; 12(3):567-70. PMID: 21344595.
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      45. McCoy LS, Xie Y, Tor Y. Antibiotics that target protein synthesis. Wiley Interdiscip Rev RNA. 2011 Mar-Apr; 2(2):209-32. PMID: 21957007.
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      46. Dix AV, Fischer L, Sarrazin S, Redgate CP, Esko JD, Tor Y. Cooperative, heparan sulfate-dependent cellular uptake of dimeric guanidinoglycosides. Chembiochem. 2010 Nov 2; 11(16):2302-10. PMID: 20931643.
        View in: PubMed
      47. Xie Y, Maxson T, Tor Y. Fluorescent nucleoside analogue displays enhanced emission upon pairing with guanine. Org Biomol Chem. 2010 Nov 21; 8(22):5053-5. PMID: 20862439.
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      48. Xie Y, Maxson T, Tor Y. Fluorescent ribonucleoside as a FRET acceptor for tryptophan in native proteins. J Am Chem Soc. 2010 Sep 1; 132(34):11896-7. PMID: 20690779.
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      49. Xie Y, Dix AV, Tor Y. Antibiotic selectivity for prokaryotic vs. eukaryotic decoding sites. Chem Commun (Camb). 2010 Aug 14; 46(30):5542-4. PMID: 20464029.
        View in: PubMed
      50. Sinkeldam RW, Greco NJ, Tor Y. Fluorescent analogs of biomolecular building blocks: design, properties, and applications. Chem Rev. 2010 May 12; 110(5):2579-619. PMID: 20205430.
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      51. Sarrazin S, Wilson B, Sly WS, Tor Y, Esko JD. Guanidinylated neomycin mediates heparan sulfate-dependent transport of active enzymes to lysosomes. Mol Ther. 2010 Jul; 18(7):1268-74. PMID: 20442709.
        View in: PubMed
      52. Xie Y, Dix AV, Tor Y. FRET enabled real time detection of RNA-small molecule binding. J Am Chem Soc. 2009 Dec 9; 131(48):17605-14. PMID: 19908830.
        View in: PubMed
      53. Rios AC, Tor Y. Model systems: how chemical biologists study RNA. Curr Opin Chem Biol. 2009 Dec; 13(5-6):660-8. PMID: 19879179.
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      54. Greco NJ, Sinkeldam RW, Tor Y. An emissive C analog distinguishes between G, 8-oxoG, and T. Org Lett. 2009 Mar 5; 11(5):1115-8. PMID: 19196162.
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      55. Srivatsan SG, Tor Y. Enzymatic incorporation of emissive pyrimidine ribonucleotides. Chem Asian J. 2009 Mar 2; 4(3):419-27. PMID: 19072942.
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      56. Belousoff MJ, Ung P, Forsyth CM, Tor Y, Spiccia L, Graham B. New macrocyclic terbium(III) complex for use in RNA footprinting experiments. J Am Chem Soc. 2009 Jan 28; 131(3):1106-14. PMID: 19119812.
        View in: PubMed
      57. Brown JR, Yang F, Sinha A, Ramakrishnan B, Tor Y, Qasba PK, Esko JD. Deoxygenated disaccharide analogs as specific inhibitors of beta1-4-galactosyltransferase 1 and selectin-mediated tumor metastasis. J Biol Chem. 2009 Feb 20; 284(8):4952-9. PMID: 19106107.
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      58. Belousoff MJ, Gasser G, Graham B, Tor Y, Spiccia L. Binding of HIV-1 TAR mRNA to a peptide nucleic acid oligomer and its conjugates with metal-ion-binding multidentate ligands. J Biol Inorg Chem. 2009 Feb; 14(2):287-300. PMID: 19015900.
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      59. Belousoff MJ, Graham B, Spiccia L, Tor Y. Cleavage of RNA oligonucleotides by aminoglycosides. Org Biomol Chem. 2009 Jan 7; 7(1):30-3. PMID: 19081939.
        View in: PubMed
      60. Schuksz M, Fuster MM, Brown JR, Crawford BE, Ditto DP, Lawrence R, Glass CA, Wang L, Tor Y, Esko JD. Surfen, a small molecule antagonist of heparan sulfate. Proc Natl Acad Sci U S A. 2008 Sep 2; 105(35):13075-80. PMID: 18725627.
        View in: PubMed
      61. Sinkeldam RW, Greco NJ, Tor Y. Polarity of major grooves explored by using an isosteric emissive nucleoside. Chembiochem. 2008 Mar 25; 9(5):706-9. PMID: 18286575.
        View in: PubMed
      62. Srivatsan SG, Weizman H, Tor Y. A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing. Org Biomol Chem. 2008 Apr 21; 6(8):1334-8. PMID: 18385838.
        View in: PubMed
      63. Staple DW, Venditti V, Niccolai N, Elson-Schwab L, Tor Y, Butcher SE. Guanidinoneomycin B recognition of an HIV-1 RNA helix. Chembiochem. 2008 Jan 4; 9(1):93-102. PMID: 18058789.
        View in: PubMed
      64. Srivatsan SG, Greco NJ, Tor Y. A highly emissive fluorescent nucleoside that signals the activity of toxic ribosome-inactivating proteins. Angew Chem Int Ed Engl. 2008; 47(35):6661-5. PMID: 18683267.
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      65. Sinkeldam RW, Tor Y. To D or not to D? On estimating the microenvironment polarity of biomolecular cavities. Org Biomol Chem. 2007 Aug 21; 5(16):2523-8. PMID: 18019524.
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      66. Glazer EC, Magde D, Tor Y. Ruthenium complexes that break the rules: structural features controlling dual emission. J Am Chem Soc. 2007 Jul 11; 129(27):8544-51. PMID: 17571887.
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      67. Greco NJ, Tor Y. Furan Decorated Nucleoside Analogues as Fluorescent Probes: synthesis, photophysical evaluation and site-specific incorporation. Tetrahedron. 2007 Apr 23; 63(17):3515-3527. PMID: 18431439.
        View in: PubMed
      68. Srivatsan SG, Tor Y. Using an emissive uridine analogue for assembling fluorescent HIV-1 TAR constructs. Tetrahedron. 2007 Apr 23; 63(17):3601-3607. PMID: 18431440.
        View in: PubMed
      69. Barbieri CM, Kaul M, Bozza-Hingos M, Zhao F, Tor Y, Hermann T, Pilch DS. Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: importance of the 2'-amino functionality. Antimicrob Agents Chemother. 2007 May; 51(5):1760-9. PMID: 17353247.
        View in: PubMed
      70. Tam VK, Kwong D, Tor Y. Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery. J Am Chem Soc. 2007 Mar 21; 129(11):3257-66. PMID: 17319662.
        View in: PubMed
      71. Elson-Schwab L, Garner OB, Schuksz M, Crawford BE, Esko JD, Tor Y. Guanidinylated neomycin delivers large, bioactive cargo into cells through a heparan sulfate-dependent pathway. J Biol Chem. 2007 May 4; 282(18):13585-91. PMID: 17311923.
        View in: PubMed
      72. Srivatsan SG, Tor Y. Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization. J Am Chem Soc. 2007 Feb 21; 129(7):2044-53. PMID: 17256858.
        View in: PubMed
      73. Greco NJ, Tor Y. Synthesis and site-specific incorporation of a simple fluorescent pyrimidine. Nat Protoc. 2007; 2(2):305-16. PMID: 17406590.
        View in: PubMed
      74. Srivatsan SG, Tor Y. Synthesis and enzymatic incorporation of a fluorescent pyrimidine ribonucleotide. Nat Protoc. 2007; 2(6):1547-55. PMID: 17571062.
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      75. Yu DH, Macdonald J, Josephs S, Liu Q, Nguy V, Tor Y, Wong-Staal F, Li QX. MDDD, a 4,9-diazapyrenium derivative, is selectively toxic to glioma cells by inducing growth arrest at G0/G1 independently of p53. Invest New Drugs. 2006 Nov; 24(6):489-98. PMID: 16633716.
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      76. Blount KF, Tor Y. A tale of two targets: differential RNA selectivity of nucleobase-aminoglycoside conjugates. Chembiochem. 2006 Oct; 7(10):1612-21. PMID: 16915600.
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      77. Yang G, Trylska J, Tor Y, McCammon JA. Binding of aminoglycosidic antibiotics to the oligonucleotide A-site model and 30S ribosomal subunit: Poisson-Boltzmann model, thermal denaturation, and fluorescence studies. J Med Chem. 2006 Sep 7; 49(18):5478-90. PMID: 16942021.
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      78. Talley TT, Yalda S, Ho KY, Tor Y, Soti FS, Kem WR, Taylor P. Spectroscopic analysis of benzylidene anabaseine complexes with acetylcholine binding proteins as models for ligand-nicotinic receptor interactions. Biochemistry. 2006 Jul 25; 45(29):8894-902. PMID: 16846232.
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      79. Jaramillo D, Wheate NJ, Ralph SF, Howard WA, Tor Y, Aldrich-Wright JR. Polyamide platinum anticancer complexes designed to target specific DNA sequences. Inorg Chem. 2006 Jul 24; 45(15):6004-13. PMID: 16842007.
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      80. Tam VK, Liu Q, Tor Y. Extended ethidium bromide analogue as a triple helix intercalator: synthesis, photophysical properties and nucleic acids binding. Chem Commun (Camb). 2006 Jul 5; (25):2684-6. PMID: 16786087.
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      81. Jouvenot D, Glazer EC, Tor Y. Photodimerizable ditopic ligand. Org Lett. 2006 May 11; 8(10):1987-90. PMID: 16671763.
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      82. Greco NJ, Hysell M, Goldenberg JR, Rheingold AL, Tor Y. Alkyne-containing chelating ligands: synthesis, properties and metal coordination of 1,2-di(quinolin-8-yl)ethyne. Dalton Trans. 2006 May 21; (19):2288-90. PMID: 16688316.
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      83. Tor Y. The ribosomal A-site as an inspiration for the design of RNA binders. Biochimie. 2006 Aug; 88(8):1045-51. PMID: 16581175.
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      84. Zhao F, Zhao Q, Blount KF, Han Q, Tor Y, Hermann T. Molecular recognition of RNA by neomycin and a restricted neomycin derivative. Angew Chem Int Ed Engl. 2005 Aug 19; 44(33):5329-34. PMID: 16037995.
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      85. Greco NJ, Tor Y. Simple fluorescent pyrimidine analogues detect the presence of DNA abasic sites. J Am Chem Soc. 2005 Aug 10; 127(31):10784-5. PMID: 16076156.
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      86. Hysell M, Siegel JS, Tor Y. Synthesis and stability of exocyclic triazine nucleosides. Org Biomol Chem. 2005 Aug 21; 3(16):2946-52. PMID: 16186926.
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      87. Blount KF, Zhao F, Hermann T, Tor Y. Conformational constraint as a means for understanding RNA-aminoglycoside specificity. J Am Chem Soc. 2005 Jul 13; 127(27):9818-29. PMID: 15998086.
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      88. Siegel JS, Tor Y. Genetic alphabetic order: what came before A? Org Biomol Chem. 2005 May 7; 3(9):1591-2. PMID: 15858634.
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      89. Glazer EC, Magde D, Tor Y. Dual emission from a family of conjugated dinuclear Ru(II) complexes. J Am Chem Soc. 2005 Mar 30; 127(12):4190-2. PMID: 15783199.
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      90. Boer J, Blount KF, Luedtke NW, Elson-Schwab L, Tor Y. RNA-selective modification by a platinum(II) complex conjugated to amino- and guanidinoglycosides. Angew Chem Int Ed Engl. 2005 Jan 28; 44(6):927-32. PMID: 15630712.
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      91. Luedtke NW, Liu Q, Tor Y. On the electronic structure of ethidium. Chemistry. 2005 Jan 7; 11(2):495-508. PMID: 15549769.
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      92. Jaramillo D, Liu Q, Aldrich-Wright J, Tor Y. Synthesis of N-methylpyrrole and N-methylimidazole amino acids suitable for solid-phase synthesis. J Org Chem. 2004 Nov 12; 69(23):8151-3. PMID: 15527311.
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      93. Aldrich-Wright J, Brodie C, Glazer EC, Luedtke NW, Elson-Schwab L, Tor Y. Symmetrical dinuclear complexes with high DNA affinity based on [Ru(dpq)2(phen)]2+. Chem Commun (Camb). 2004 Apr 21; (8):1018-9. PMID: 15069523.
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      94. Luedtke NW, Liu Q, Tor Y. Synthesis, photophysical properties, and nucleic acid binding of phenanthridinium derivatives based on ethidium. Bioorg Med Chem. 2003 Nov 17; 11(23):5235-47. PMID: 14604688.
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      95. Luedtke NW, Carmichael P, Tor Y. Cellular uptake of aminoglycosides, guanidinoglycosides, and poly-arginine. J Am Chem Soc. 2003 Oct 15; 125(41):12374-5. PMID: 14531657.
        View in: PubMed
      96. Luedtke NW, Liu Q, Tor Y. RNA-ligand interactions: affinity and specificity of aminoglycoside dimers and acridine conjugates to the HIV-1 Rev response element. Biochemistry. 2003 Oct 7; 42(39):11391-403. PMID: 14516190.
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      97. Tor Y. Targeting RNA with small molecules. Chembiochem. 2003 Oct 6; 4(10):998-1007. PMID: 14523917.
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      98. Blount KF, Tor Y. Using pyrene-labeled HIV-1 TAR to measure RNA-small molecule binding. Nucleic Acids Res. 2003 Oct 1; 31(19):5490-500. PMID: 14500811.
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      99. Luedtke NW, Hwang JS, Nava E, Gut D, Kol M, Tor Y. The DNA and RNA specificity of eilatin Ru(II) complexes as compared to eilatin and ethidium bromide. Nucleic Acids Res. 2003 Oct 1; 31(19):5732-40. PMID: 14500837.
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      100. Luedtke NW, Tor Y. Fluorescence-based methods for evaluating the RNA affinity and specificity of HIV-1 Rev-RRE inhibitors. Biopolymers. 2003 Sep; 70(1):103-19. PMID: 12925996.
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      101. Liu Q, Tor Y. Simple conversion of aromatic amines into azides. Org Lett. 2003 Jul 10; 5(14):2571-2. PMID: 12841783.
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      102. Fineberg K, Fineberg T, Graessmann A, Luedtke NW, Tor Y, Lixin R, Jans DA, Loyter A. Inhibition of nuclear import mediated by the Rev-arginine rich motif by RNA molecules. Biochemistry. 2003 Mar 11; 42(9):2625-33. PMID: 12614157.
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      103. Hurley DJ, Tor Y. Donor/acceptor interactions in systematically modified Ru(II)-Os(II) oligonucleotides. J Am Chem Soc. 2002 Nov 6; 124(44):13231-41. PMID: 12405852.
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      104. Glazer EC, Tor Y. RuII complexes of "large-surface" ligands. Angew Chem Int Ed Engl. 2002 Nov 4; 41(21):4022-6. PMID: 12412069.
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      105. Luedtke NW, Hwang JS, Glazer EC, Gut D, Kol M, Tor Y. Eilatin Ru(II) complexes display anti-HIV activity and enantiomeric diversity in the binding of RNA. Chembiochem. 2002 Aug 2; 3(8):766-71. PMID: 12203975.
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      106. Hurley DJ, Seaman SE, Mazura JC, Tor Y. Fluorescent 1,10-phenanthroline-containing oligonucleotides distinguish between perfect and mismatched base pairing. Org Lett. 2002 Jul 11; 4(14):2305-8. PMID: 12098233.
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      107. Hurley DJ, Tor Y. Ru(II) and Os(II) nucleosides and oligonucleotides: synthesis and properties. J Am Chem Soc. 2002 Apr 10; 124(14):3749-62. PMID: 11929265.
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      108. Weizman H, Tor Y. Redox-active metal-containing nucleotides: synthesis, tunability, and enzymatic incorporation into DNA. J Am Chem Soc. 2002 Feb 27; 124(8):1568-9. PMID: 11853418.
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      109. Kirk SR, Luedtke NW, Tor Y. 2-Aminopurine as a real-time probe of enzymatic cleavage and inhibition of hammerhead ribozymes. Bioorg Med Chem. 2001 Sep; 9(9):2295-301. PMID: 11553468.
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      110. Weizman H, Tor Y. 2,2'-Bipyridine ligandoside: a novel building block for modifying DNA with intra-duplex metal complexes. J Am Chem Soc. 2001 Apr 11; 123(14):3375-6. PMID: 11457077.
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      111. Baker TJ, Luedtke NW, Tor Y, Goodman M. Synthesis and anti-HIV activity of guanidinoglycosides. J Org Chem. 2000 Dec 29; 65(26):9054-8. PMID: 11149851.
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      112. Kirk SR, Tor Y. tRNA(Phe) binds aminoglycoside antibiotics. Bioorg Med Chem. 1999 Sep; 7(9):1979-91. PMID: 10530947.
        View in: PubMed
      113. Michael K, Wang H, Tor Y. Enhanced RNA binding of dimerized aminoglycosides. Bioorg Med Chem. 1999 Jul; 7(7):1361-71. PMID: 10465410.
        View in: PubMed
      114. Wang H, Tor Y. Tobramycin-EDTA conjugate: a noninnocent affinity-cleaving reagent. Bioorg Med Chem Lett. 1998 Dec 15; 8(24):3665-70. PMID: 9934492.
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      115. Tor Y, Hermann T, Westhof E. Deciphering RNA recognition: aminoglycoside binding to the hammerhead ribozyme. Chem Biol. 1998 Nov; 5(11):R277-83. PMID: 9831530.
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