Jerrold Olefsky

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Effects of Fractalkine on Beta Cell Function
    NIH R01DK101395Sep 19, 2014 - Aug 31, 2018
    Role: Principal Investigator
    Energetics & Breast Cancer: Obesity, Inflammation, Insulin Resistance & Risk
    NIH U54CA155435Jul 7, 2011 - May 31, 2017
    Role: Co-Investigator
    Molecular Mechanisms of Inflammation, Steatosis and Hepatic Insulin Resistance
    NIH R24DK090962Sep 30, 2010 - Aug 31, 2012
    Role: Principal Investigator
    Gene Networks controlling macrophage-adipocyte interactions in insulin
    NIH/NIDDK P01DK074868Apr 1, 2006 - Apr 30, 2017
    Role: Co-Investigator
    Estrogen Effects in Insulin Target and Granulosa Cells
    NIH R55DK068606Sep 30, 2004 - Aug 31, 2006
    Role: Principal Investigator
    Diabetes Research Center (DRC)
    NIH P30DK063491Dec 1, 2002 - Jun 30, 2025
    Role: Principal Investigator
    Estrogens and Insulin Resistance in Women
    NIH R01DK061964Jul 1, 2002 - May 31, 2007
    Role: Principal Investigator
    PKA & PKC Targeting Mechanisms (Program Project)
    NIH P01DK054441Dec 15, 1998 - Mar 31, 2019
    Role: Co-Investigator
    12/22 Limited Competition for the Continuation of the Diabetes Prevention Program Outcomes Study (DPPOS) - Clinical Center
    NIH U01DK048339Sep 10, 1994 - Jan 31, 2022
    Role: Principal Investigator
    Training Program in Diabetes Research
    NIH T32DK007494Jul 1, 1984 - Aug 31, 2022
    Role: Principal Investigator
    TRAINING PROGRAM IN DIABETES RESEARCH
    NIH T32AM007494Jul 1, 1984 - Jun 30, 1989
    Role: Principal Investigator
    Insulin Receptors and the Glucose Transport System
    NIH R01DK033651Aug 1, 1983 - Jun 30, 2014
    Role: Principal Investigator
    INSULIN RECEPTORS AND THE GLUCOSE TRANSPORT SYSTEM
    NIH R37DK033651Aug 1, 1983 - Jun 30, 2010
    Role: Principal Investigator
    MECHANISMS OF INSULIN RESISTANCE IN MAN
    NIH R01DK033649Aug 1, 1983 - Mar 31, 2002
    Role: Principal Investigator
    MECHANISMS OF INSULIN RESISTANCE IN MAN
    NIH R37DK033649Aug 1, 1983 - Mar 31, 1998
    Role: Principal Investigator
    INSULIN RECEPTORS AND THE GLUCOSE TRANSPORT SYSTEM
    NIH R01AM033651Aug 1, 1983 - Mar 31, 1990
    Role: Principal Investigator
    MECHANISMS OF INSULIN RESISTANCE IN MAN
    NIH R01AM033649Aug 1, 1983 - May 31, 1989
    Role: Principal Investigator
    Center for Reproductive Science and Medicine
    NIH U54HD012303Dec 1, 1978 - Jul 31, 2016
    Role: Co-Investigator
    General Clinical Research Center
    NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Adipose tissue macrophages secrete small extracellular vesicles that mediate rosiglitazone-induced insulin sensitization. Nat Metab. 2024 Apr 11. Rohm TV, Castellani Gomes Dos Reis F, Isaac R, Murphy C, Cunha E Rocha K, Bandyopadhyay G, Gao H, Libster AM, Zapata RC, Lee YS, Ying W, Miciano C, Wang A, Olefsky JM. PMID: 38605183.
      View in: PubMed   Mentions:
    2. Exosome-Mediated Impact on Systemic Metabolism. Annu Rev Physiol. 2024 Feb 12; 86:225-253. Cunha E Rocha K, Ying W, Olefsky JM. PMID: 38345906.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Far-red chemigenetic biosensors for multi-dimensional and super-resolved kinase activity imaging. bioRxiv. 2024 Feb 11. Frei MS, Sanchez SA, Liu L, Schneider F, Wang Z, Hakozaki H, Li Y, Lyons AC, Rohm TV, Olefsky JM, Shi L, Schöneberg J, Fraser SE, Mehta S, Wang Y, Zhang J. PMID: 38370804; PMCID: PMC10871310.
      View in: PubMed   Mentions:
    4. Human gain-of-function variants in HNF1A confer protection from diabetes but independently increase hepatic secretion of atherogenic lipoproteins. Cell Genom. 2023 Jul 12; 3(7):100339. DeForest N, Kavitha B, Hu S, Isaac R, Krohn L, Wang M, Du X, De Arruda Saldanha C, Gylys J, Merli E, Abagyan R, Najmi L, Mohan V, Alnylam Human Genetics, AMP-T2D Consortium, Flannick J, Peloso GM, Gordts PLSM, Heinz S, Deaton AM, Khera AV, Olefsky J, Radha V, Majithia AR. PMID: 37492105; PMCID: PMC10363808.
      View in: PubMed   Mentions: 2  
    5. Eating macrophages for a healthy anti-NASH meal. Immunity. 2023 01 10; 56(1):3-5. Lee YS, Olefsky J. PMID: 36630915; PMCID: PMC10441811.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH. Cell Metab. 2022 07 05; 34(7):978-990.e4. Gao H, Jin Z, Bandyopadhyay G, Cunha E Rocha K, Liu X, Zhao H, Zhang D, Jouihan H, Pourshahian S, Kisseleva T, Brenner DA, Ying W, Olefsky JM. PMID: 35700738; PMCID: PMC9262870.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    7. Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth. Nat Cell Biol. 2022 06; 24(6):954-967. Cao M, Isaac R, Yan W, Ruan X, Jiang L, Wan Y, Wang J, Wang E, Caron C, Neben S, Drygin D, Pizzo DP, Wu X, Liu X, Chin AR, Fong MY, Gao Z, Guo K, Fadare O, Schwab RB, Yuan Y, Yost SE, Mortimer J, Zhong W, Ying W, Bui JD, Sears DD, Olefsky JM, Wang SE. PMID: 35637408; PMCID: PMC9233030.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    8. Extracellular Vesicles and Their Emerging Roles as Cellular Messengers in Endocrinology: An Endocrine Society Scientific Statement. Endocr Rev. 2022 05 12; 43(3):441-468. Salomon C, Das S, Erdbrügger U, Kalluri R, Kiang Lim S, Olefsky JM, Rice GE, Sahoo S, Andy Tao W, Vader P, Wang Q, Weaver AM. PMID: 35552682; PMCID: PMC10686249.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    9. Inflammation in obesity, diabetes, and related disorders. Immunity. 2022 01 11; 55(1):31-55. Rohm TV, Meier DT, Olefsky JM, Donath MY. PMID: 35021057; PMCID: PMC8773457.
      View in: PubMed   Mentions: 263     Fields:    Translation:HumansAnimals
    10. Exosomes as mediators of intercellular crosstalk in metabolism. Cell Metab. 2021 09 07; 33(9):1744-1762. Isaac R, Reis FCG, Ying W, Olefsky JM. PMID: 34496230; PMCID: PMC8428804.
      View in: PubMed   Mentions: 150     Fields:    Translation:HumansCells
    11. Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075. Nat Metab. 2021 09; 3(9):1163-1174. Ji Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM. PMID: 34489604; PMCID: PMC8460610.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    12. Chronic tissue inflammation and metabolic disease. Genes Dev. 2021 03 01; 35(5-6):307-328. Lee YS, Olefsky J. PMID: 33649162; PMCID: PMC7919414.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansCells
    13. MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice. Cell Metab. 2021 04 06; 33(4):781-790.e5. Ying W, Gao H, Dos Reis FCG, Bandyopadhyay G, Ofrecio JM, Luo Z, Ji Y, Jin Z, Ly C, Olefsky JM. PMID: 33450179; PMCID: PMC8035248.
      View in: PubMed   Mentions: 86     Fields:    Translation:AnimalsCells
    14. Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity. Cell Metab. 2020 06 02; 31(6):1173-1188.e5. Paschoal VA, Walenta E, Talukdar S, Pessentheiner AR, Osborn O, Hah N, Chi TJ, Tye GL, Armando AM, Evans RM, Chi NW, Quehenberger O, Olefsky JM, Oh DY. PMID: 32413335; PMCID: PMC7337476.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    15. A Tribute to Robert Roy Henry-The Classic "Academic Triple Threat": Accomplished Researcher, Inspiring Teacher, and Compassionate Clinician. Diabetes Care. 2020 03; 43(3):522-525. Edelman S, Olefsky J, Mudaliar S, Ciaraldi T, Baron A. PMID: 31964787.
      View in: PubMed   Mentions:    Fields:    
    16. The role of macrophages in obesity-associated islet inflammation and β-cell abnormalities. Nat Rev Endocrinol. 2020 02; 16(2):81-90. Ying W, Fu W, Lee YS, Olefsky JM. PMID: 31836875; PMCID: PMC8315273.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    17. Obesity Modulates Intestinal Intraepithelial T Cell Persistence, CD103 and CCR9 Expression, and Outcome in Dextran Sulfate Sodium-Induced Colitis. J Immunol. 2019 12 15; 203(12):3427-3435. Park C, Cheung KP, Limon N, Costanzo A, Barba C, Miranda N, Gargas S, Johnson AMF, Olefsky JM, Jameson JM. PMID: 31712385.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    18. TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance. Cell Metab. 2020 01 07; 31(1):162-173.e5. El Ouarrat D, Isaac R, Lee YS, Oh DY, Wollam J, Lackey D, Riopel M, Bandyopadhyay G, Seo JB, Sampath-Kumar R, Olefsky JM. PMID: 31708444; PMCID: PMC7784082.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    19. Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance. Diabetes. 2019 07; 68(7):1415-1426. Wollam J, Riopel M, Xu YJ, Johnson AMF, Ofrecio JM, Ying W, El Ouarrat D, Chan LS, Han AW, Mahmood NA, Ryan CN, Lee YS, Watrous JD, Chordia MD, Pan D, Jain M, Olefsky JM. PMID: 31010956; PMCID: PMC6609982.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    20. Role of Host GPR120 in Mediating Dietary Omega-3 Fatty Acid Inhibition of Prostate Cancer. J Natl Cancer Inst. 2019 01 01; 111(1):52-59. Liang P, Henning SM, Guan J, Grogan T, Elashoff D, Olefsky JM, Cohen P, Aronson WJ. PMID: 30202902; PMCID: PMC6335116.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    21. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity. Cell Metab. 2019 02 05; 29(2):457-474.e5. Ying W, Lee YS, Dong Y, Seidman JS, Yang M, Isaac R, Seo JB, Yang BH, Wollam J, Riopel M, McNelis J, Glass CK, Olefsky JM, Fu W. PMID: 30595478; PMCID: PMC6701710.
      View in: PubMed   Mentions: 102     Fields:    Translation:AnimalsCells
    22. Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction. J Endocr Soc. 2019 Feb 01; 3(2):427-445. Rickert E, Fernandez MO, Choi I, Gorman M, Olefsky JM, Webster NJG. PMID: 30746504; PMCID: PMC6364627.
      View in: PubMed   Mentions: 5  
    23. CX3CL1-Fc treatment prevents atherosclerosis in Ldlr KO mice. Mol Metab. 2019 02; 20:89-101. Riopel M, Vassallo M, Ehinger E, Pattison J, Bowden K, Winkels H, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Larson CJ, Ley K, Cabrales P, Witztum JL, Olefsky JM, Lee YS. PMID: 30553772; PMCID: PMC6358552.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    24. Knockdown of Ant2 Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity. Nat Metab. 2019 01; 1(1):86-97. Seo JB, Riopel M, Cabrales P, Huh JY, Bandyopadhyay GK, Andreyev AY, Murphy AN, Beeman SC, Smith GI, Klein S, Lee YS, Olefsky JM. PMID: 31528845; PMCID: PMC6746433.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    25. N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model. Bioorg Med Chem. 2018 10 01; 26(18):5169-5180. Hoveyda HR, Fraser GL, Zoute L, Dutheuil G, Schils D, Brantis C, Lapin A, Parcq J, Guitard S, Lenoir F, Bousmaqui ME, Rorive S, Hospied S, Blanc S, Bernard J, Ooms F, McNelis JC, Olefsky JM. PMID: 30253886.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    26. Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis. Arthritis Res Ther. 2018 07 11; 20(1):145. Korman B, Marangoni RG, Lord G, Olefsky J, Tourtellotte W, Varga J. PMID: 29996896; PMCID: PMC6042240.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    27. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proc Natl Acad Sci U S A. 2018 07 24; 115(30):7819-7824. Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, Saltiel AR. PMID: 29915037; PMCID: PMC6065037.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    28. Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function. J Clin Invest. 2018 04 02; 128(4):1458-1470. Riopel M, Seo JB, Bandyopadhyay GK, Li P, Wollam J, Chung H, Jung SR, Murphy A, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, Koh DS, Larson CJ, Olefsky JM, Lee YS. PMID: 29504946; PMCID: PMC5873865.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    29. An Integrated View of Immunometabolism. Cell. 2018 01 11; 172(1-2):22-40. Lee YS, Wollam J, Olefsky JM. PMID: 29328913; PMCID: PMC8451723.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimals
    30. Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. Cell. 2017 Oct 05; 171(2):372-384.e12. Ying W, Riopel M, Bandyopadhyay G, Dong Y, Birmingham A, Seo JB, Ofrecio JM, Wollam J, Hernandez-Carretero A, Fu W, Li P, Olefsky JM. PMID: 28942920.
      View in: PubMed   Mentions: 508     Fields:    Translation:AnimalsCells
    31. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. J Clin Invest. 2017 Mar 01; 127(3):1019-1030. Ying W, Wollam J, Ofrecio JM, Bandyopadhyay G, El Ouarrat D, Lee YS, Oh DY, Li P, Osborn O, Olefsky JM. PMID: 28192375; PMCID: PMC5330737.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    32. Inflammatory mechanisms linking obesity and metabolic disease. J Clin Invest. 2017 01 03; 127(1):1-4. Saltiel AR, Olefsky JM. PMID: 28045402; PMCID: PMC5199709.
      View in: PubMed   Mentions: 714     Fields:    Translation:HumansAnimals
    33. Obese Neuronal PPARγ Knockout Mice Are Leptin Sensitive but Show Impaired Glucose Tolerance and Fertility. Endocrinology. 2017 01 01; 158(1):121-133. Fernandez MO, Sharma S, Kim S, Rickert E, Hsueh K, Hwang V, Olefsky JM, Webster NJ. PMID: 27841948; PMCID: PMC5412981.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    34. Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance. Cell. 2016 11 03; 167(4):973-984.e12. Li P, Liu S, Lu M, Bandyopadhyay G, Oh D, Imamura T, Johnson AMF, Sears D, Shen Z, Cui B, Kong L, Hou S, Liang X, Iovino S, Watkins SM, Ying W, Osborn O, Wollam J, Brenner M, Olefsky JM. PMID: 27814523; PMCID: PMC5179329.
      View in: PubMed   Mentions: 127     Fields:    Translation:HumansAnimalsCells
    35. G protein-coupled receptors as targets for anti-diabetic therapeutics. Nat Rev Drug Discov. 2016 03; 15(3):161-72. Oh DY, Olefsky JM. PMID: 26822831.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimals
    36. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Rep. 2016 Jan 12; 14(2):255-68. Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, Olefsky JM, Akassoglou K. PMID: 26748707; PMCID: PMC4831919.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    37. Regulation of metabolism by the innate immune system. Nat Rev Endocrinol. 2016 Jan; 12(1):15-28. Lackey DE, Olefsky JM. PMID: 26553134.
      View in: PubMed   Mentions: 288     Fields:    Translation:HumansAnimals
    38. Spatial Cognition in Adult and Aged Mice Exposed to High-Fat Diet. PLoS One. 2015; 10(10):e0140034. Kesby JP, Kim JJ, Scadeng M, Woods G, Kado DM, Olefsky JM, Jeste DV, Achim CL, Semenova S. PMID: 26448649; PMCID: PMC4598128.
      View in: PubMed   Mentions: 35     Fields:    Translation:Animals
    39. GPR43 Potentiates β-Cell Function in Obesity. Diabetes. 2015 Sep; 64(9):3203-17. McNelis JC, Lee YS, Mayoral R, van der Kant R, Johnson AM, Wollam J, Olefsky JM. PMID: 26023106; PMCID: PMC4542437.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    40. High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. PLoS One. 2015; 10(4):e0122195. Johnson AM, Costanzo A, Gareau MG, Armando AM, Quehenberger O, Jameson JM, Olefsky JM. PMID: 25837594; PMCID: PMC4383570.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    41. Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Mol Metab. 2015 May; 4(5):378-91. Mayoral R, Osborn O, McNelis J, Johnson AM, Oh DY, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, Olefsky JM. PMID: 25973386; PMCID: PMC4421024.
      View in: PubMed   Mentions: 71     Fields:    
    42. Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 2015 Apr 16; 520(7547):388. Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. PMID: 25739500.
      View in: PubMed   Mentions: 3     Fields:    
    43. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. Nat Med. 2015 Mar; 21(3):239-247. Li P, Oh DY, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM. PMID: 25706874; PMCID: PMC4429798.
      View in: PubMed   Mentions: 146     Fields:    Translation:AnimalsCells
    44. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nat Med. 2015 Feb; 21(2):159-65. Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, Coulter S, Liddle C, Schoonjans K, Olefsky JM, Saltiel AR, Downes M, Evans RM. PMID: 25559344; PMCID: PMC4320010.
      View in: PubMed   Mentions: 306     Fields:    Translation:Animals
    45. Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice. Diabetes. 2015 Apr; 64(4):1120-30. Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh DY. PMID: 25315009; PMCID: PMC4375077.
      View in: PubMed   Mentions: 88     Fields:    Translation:AnimalsCells
    46. Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer. Oncogene. 2015 Jul; 34(27):3504-13. Chung H, Lee YS, Mayoral R, Oh DY, Siu JT, Webster NJ, Sears DD, Olefsky JM, Ellies LG. PMID: 25220417; PMCID: PMC4362785.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    47. Macrophages, immunity, and metabolic disease. Immunity. 2014 Jul 17; 41(1):36-48. McNelis JC, Olefsky JM. PMID: 25035952.
      View in: PubMed   Mentions: 334     Fields:    Translation:HumansAnimalsCells
    48. Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 2014 Sep 18; 513(7518):436-9. Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, Atkins AR, Olefsky JM, Mohammadi M, Downes M, Evans RM. PMID: 25043058; PMCID: PMC4184286.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimals
    49. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nat Med. 2014 Aug; 20(8):942-7. Oh DY, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, Chung H, Evans RM, Quehenberger O, McNelis J, Bogner-Strauss JG, Olefsky JM. PMID: 24997608; PMCID: PMC4126875.
      View in: PubMed   Mentions: 127     Fields:    Translation:AnimalsCells
    50. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. J Clin Invest. 2014 Aug; 124(8):3566-78. Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, Sears DD, Olefsky JM, Karin M, Brenner DA, Seki E. PMID: 24983318; PMCID: PMC4109552.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    51. Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity. Cell. 2014 Jun 05; 157(6):1339-1352. Lee YS, Kim JW, Osborne O, Oh DY, Sasik R, Schenk S, Chen A, Chung H, Murphy A, Watkins SM, Quehenberger O, Johnson RS, Olefsky JM. PMID: 24906151; PMCID: PMC4114226.
      View in: PubMed   Mentions: 265     Fields:    Translation:AnimalsCells
    52. C/EBPα regulates macrophage activation and systemic metabolism. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1144-54. Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. PMID: 24691027; PMCID: PMC4025063.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    53. Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans. Obesity (Silver Spring). 2014 Mar; 22(3):747-57. Fink LN, Costford SR, Lee YS, Jensen TE, Bilan PJ, Oberbach A, Blüher M, Olefsky JM, Sams A, Klip A. PMID: 24030890.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    54. NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell. 2013 Sep 26; 155(1):200-214. Li P, Spann NJ, Kaikkonen MU, Lu M, Oh DY, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, Auwerx J, Glass CK, Olefsky JM. PMID: 24074869; PMCID: PMC4131699.
      View in: PubMed   Mentions: 92     Fields:    Translation:AnimalsCells
    55. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. J Clin Invest. 2013 Oct; 123(10):4318-28. Ravnskjaer K, Hogan MF, Lackey D, Tora L, Dent SY, Olefsky J, Montminy M. PMID: 24051374; PMCID: PMC3784539.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    56. Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice. Mol Cell Proteomics. 2013 Dec; 12(12):3744-58. Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS. PMID: 24030101; PMCID: PMC3861721.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    57. The fractalkine/CX3CR1 system regulates β cell function and insulin secretion. Cell. 2013 Apr 11; 153(2):413-25. Lee YS, Morinaga H, Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky J. PMID: 23582329; PMCID: PMC3717389.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    58. Free fatty acids induce Lhb mRNA but suppress Fshb mRNA in pituitary LβT2 gonadotropes and diet-induced obesity reduces FSH levels in male mice and disrupts the proestrous LH/FSH surge in female mice. Endocrinology. 2013 Jun; 154(6):2188-99. Sharma S, Morinaga H, Hwang V, Fan W, Fernandez MO, Varki N, Olefsky JM, Webster NJ. PMID: 23525221; PMCID: PMC3740488.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    59. Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues. J Biol Chem. 2013 Apr 12; 288(15):10722-35. Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. PMID: 23457303; PMCID: PMC3624452.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    60. The origins and drivers of insulin resistance. Cell. 2013 Feb 14; 152(4):673-84. Johnson AM, Olefsky JM. PMID: 23415219.
      View in: PubMed   Mentions: 260     Fields:    Translation:HumansCells
    61. An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar; 19(3):313-21. Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, Li P, Olefsky JM, Saltiel AR. PMID: 23396211; PMCID: PMC3594079.
      View in: PubMed   Mentions: 215     Fields:    Translation:AnimalsCells
    62. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design. Cancer Causes Control. 2013 Apr; 24(4):695-704. Patterson RE, Colditz GA, Hu FB, Schmitz KH, Ahima RS, Brownson RC, Carson KR, Chavarro JE, Chodosh LA, Gehlert S, Gill J, Glanz K, Haire-Joshu D, Herbst KL, Hoehner CM, Hovmand PS, Irwin ML, Jacobs LA, James AS, Jones LW, Kerr J, Kibel AS, King IB, Ligibel JA, Meyerhardt JA, Natarajan L, Neuhouser ML, Olefsky JM, Proctor EK, Redline S, Rock CL, Rosner B, Sarwer DB, Schwartz JS, Sears DD, Sesso HD, Stampfer MJ, Subramanian SV, Taveras EM, Tchou J, Thompson B, Troxel AB, Wessling-Resnick M, Wolin KY, Thornquist MD. PMID: 23378138; PMCID: PMC3602225.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    63. Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in Zucker fa/fa rats. Diabetes. 2013 Apr; 62(4):1074-83. Jiao J, Bae EJ, Bandyopadhyay G, Oliver J, Marathe C, Chen M, Hsu JY, Chen Y, Tian H, Olefsky JM, Saberi M. PMID: 23248171; PMCID: PMC3609588.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    64. Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients. Diabetes. 2013 Mar; 62(3):855-63. Qatanani M, Tan Y, Dobrin R, Greenawalt DM, Hu G, Zhao W, Olefsky JM, Sears DD, Kaplan LM, Kemp DM. PMID: 23223024; PMCID: PMC3581230.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    65. Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metab. 2012 Sep 05; 16(3):311-21. Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, Foretz M, Viollet B, Olefsky J, Karin M. PMID: 22958918; PMCID: PMC3687365.
      View in: PubMed   Mentions: 141     Fields:    Translation:Animals
    66. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nat Med. 2012 Sep; 18(9):1407-12. Talukdar S, Oh DY, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, Ofrecio J, Lin M, Brenner MB, Olefsky JM. PMID: 22863787; PMCID: PMC3491143.
      View in: PubMed   Mentions: 460     Fields:    Translation:AnimalsCells
    67. Fetuin-A: the missing link in lipid-induced inflammation. Nat Med. 2012 Aug; 18(8):1182-3. Heinrichsdorff J, Olefsky JM. PMID: 22869185.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    68. GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity. J Immunol. 2012 Aug 15; 189(4):1992-9. Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Mamane Y, Mancini JA, Nawrocki AR, Lazarowski E, Olefsky JM, Kim JJ. PMID: 22778393; PMCID: PMC3411902.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    69. G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. J Clin Invest. 2012 Jul; 122(7):2444-53. Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, Hadcock J, Bartfai T, Olefsky JM. PMID: 22653059; PMCID: PMC3386820.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    70. A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature. 2012 May 17; 485(7398):391-4. Jonker JW, Suh JM, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin YQ, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. PMID: 22522926; PMCID: PMC3358516.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    71. Omega 3 fatty acids and GPR120. Cell Metab. 2012 May 02; 15(5):564-5. Oh DY, Olefsky JM. PMID: 22560206; PMCID: PMC3803996.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimals
    72. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metab. 2012 May 02; 15(5):635-45. Glass CK, Olefsky JM. PMID: 22560216; PMCID: PMC4156155.
      View in: PubMed   Mentions: 350     Fields:    Translation:HumansAnimalsCells
    73. Putting the brakes on FOXO1 in fat. EMBO J. 2012 May 16; 31(10):2240-1. Kim JJ, Fan W, Olefsky JM. PMID: 22510885; PMCID: PMC3364738.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    74. Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance. J Biol Chem. 2012 May 25; 287(22):18769-80. Bae EJ, Xu J, Oh DY, Bandyopadhyay G, Lagakos WS, Keshwani M, Olefsky JM. PMID: 22493495; PMCID: PMC3365775.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    75. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proc Natl Acad Sci U S A. 2012 Apr 10; 109(15):5838-43. Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K. PMID: 22460790; PMCID: PMC3326459.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    76. The cellular and signaling networks linking the immune system and metabolism in disease. Nat Med. 2012 Mar 06; 18(3):363-74. Osborn O, Olefsky JM. PMID: 22395709.
      View in: PubMed   Mentions: 652     Fields:    Translation:HumansCells
    77. Increased macrophage migration into adipose tissue in obese mice. Diabetes. 2012 Feb; 61(2):346-54. Oh DY, Morinaga H, Talukdar S, Bae EJ, Olefsky JM. PMID: 22190646; PMCID: PMC3266418.
      View in: PubMed   Mentions: 186     Fields:    Translation:AnimalsCells
    78. SirT1 regulates adipose tissue inflammation. Diabetes. 2011 Dec; 60(12):3235-45. Gillum MP, Kotas ME, Erion DM, Kursawe R, Chatterjee P, Nead KT, Muise ES, Hsiao JJ, Frederick DW, Yonemitsu S, Banks AS, Qiang L, Bhanot S, Olefsky JM, Sears DD, Caprio S, Shulman GI. PMID: 22110092; PMCID: PMC3219953.
      View in: PubMed   Mentions: 136     Fields:    Translation:HumansAnimalsCells
    79. Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity. Cell. 2011 Nov 11; 147(4):815-26. Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM. PMID: 22078880; PMCID: PMC3783197.
      View in: PubMed   Mentions: 157     Fields:    Translation:AnimalsCells
    80. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. J Clin Invest. 2011 Nov; 121(11):4281-8. Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM. PMID: 21985785; PMCID: PMC3204844.
      View in: PubMed   Mentions: 108     Fields:    Translation:AnimalsCells
    81. Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance. Diabetes. 2011 Oct; 60(10):2474-83. Lee YS, Li P, Huh JY, Hwang IJ, Lu M, Kim JI, Ham M, Talukdar S, Chen A, Lu WJ, Bandyopadhyay GK, Schwendener R, Olefsky J, Kim JB. PMID: 21911747; PMCID: PMC3178297.
      View in: PubMed   Mentions: 274     Fields:    Translation:Animals
    82. Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport. Nat Med. 2011 Aug 14; 17(9):1067-75. Ohtsubo K, Chen MZ, Olefsky JM, Marth JD. PMID: 21841783; PMCID: PMC3888087.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    83. Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases. Trends Pharmacol Sci. 2011 Sep; 32(9):543-50. Talukdar S, Olefsky JM, Osborn O. PMID: 21663979; PMCID: PMC3419590.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimals
    84. Trans-resveratrol inhibits phosphorylation of Smad2/3 and represses FSHβ gene expression by a SirT1-independent pathway in LβT2 gonadotrope cells. Reprod Toxicol. 2011 Jul; 32(1):85-92. Lan D, Lu M, Sharma S, Mellon PL, Olefsky JM, Webster NJ. PMID: 21679764; PMCID: PMC3155991.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    85. Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nat Med. 2011 May; 17(5):618-22. Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, Webster NJ, Schwartz MW, Olefsky JM. PMID: 21532596; PMCID: PMC3380629.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimalsCells
    86. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. FASEB J. 2011 Apr; 25(4):1133-44. Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M. PMID: 21163859; PMCID: PMC3058702.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    87. Fat-induced inflammation unchecked. Cell Metab. 2010 Dec 01; 12(6):553-4. Osborn O, Sears DD, Olefsky JM. PMID: 21109185.
      View in: PubMed   Mentions: 7     Fields:    
    88. PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice. Biol Reprod. 2011 Mar; 84(3):466-75. Sharma S, Sharma PM, Mistry DS, Chang RJ, Olefsky JM, Mellon PL, Webster NJ. PMID: 21076077; PMCID: PMC3043129.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    89. FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. EMBO J. 2010 Dec 15; 29(24):4223-36. Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. PMID: 21045807; PMCID: PMC3018786.
      View in: PubMed   Mentions: 118     Fields:    Translation:AnimalsCells
    90. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 2010 Sep 03; 142(5):687-98. Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM. PMID: 20813258; PMCID: PMC2956412.
      View in: PubMed   Mentions: 950     Fields:    Translation:HumansAnimalsCells
    91. Medicine. Wnt fans the flames in obesity. Science. 2010 Jul 23; 329(5990):397-8. Oh DY, Olefsky JM. PMID: 20651140.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    92. Inducible nitric oxide synthase deficiency in myeloid cells does not prevent diet-induced insulin resistance. Mol Endocrinol. 2010 Jul; 24(7):1413-22. Lu M, Li P, Pferdekamper J, Fan W, Saberi M, Schenk S, Olefsky JM. PMID: 20444886; PMCID: PMC2903908.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    93. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 2010 Jul; 139(1):323-34.e7. Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E. PMID: 20347818; PMCID: PMC4631262.
      View in: PubMed   Mentions: 370     Fields:    Translation:AnimalsCells
    94. Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. J Biol Chem. 2010 May 14; 285(20):15333-15345. Li P, Lu M, Nguyen MTA, Bae EJ, Chapman J, Feng D, Hawkins M, Pessin JE, Sears DD, Nguyen AK, Amidi A, Watkins SM, Nguyen U, Olefsky JM. PMID: 20308074; PMCID: PMC2865288.
      View in: PubMed   Mentions: 136     Fields:    Translation:AnimalsCells
    95. A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats. Am J Physiol Endocrinol Metab. 2010 May; 298(5):E1036-48. Lu M, Patsouris D, Li P, Flores-Riveros J, Frincke JM, Watkins S, Schenk S, Olefsky JM. PMID: 20159859; PMCID: PMC2867370.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    96. Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways. J Pharmacol Exp Ther. 2010 Apr; 333(1):70-80. Wang T, Villegas S, Huang Y, White SK, Ahlem C, Lu M, Olefsky JM, Reading C, Frincke JM, Alleva D, Flores-Riveros J. PMID: 20068030.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    97. Macrophages, inflammation, and insulin resistance. Annu Rev Physiol. 2010; 72:219-46. Olefsky JM, Glass CK. PMID: 20148674.
      View in: PubMed   Mentions: 1272     Fields:    Translation:HumansAnimalsCells
    98. PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52):22504-9. Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, Evans RM. PMID: 20018750; PMCID: PMC2794650.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    99. SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. Am J Physiol Endocrinol Metab. 2010 Mar; 298(3):E419-28. Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM. PMID: 19996381; PMCID: PMC2838524.
      View in: PubMed   Mentions: 195     Fields:    Translation:AnimalsCells
    100. Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metab. 2009 Nov; 10(5):419-29. Saberi M, Woods NB, de Luca C, Schenk S, Lu JC, Bandyopadhyay G, Verma IM, Olefsky JM. PMID: 19883619; PMCID: PMC2790319.
      View in: PubMed   Mentions: 227     Fields:    Translation:AnimalsCells
    101. Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment. J Biol Chem. 2009 Nov 06; 284(45):31223-35. Patsouris D, Neels JG, Fan W, Li PP, Nguyen MT, Olefsky JM. PMID: 19740750; PMCID: PMC2781521.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    102. IKKepsilon: a bridge between obesity and inflammation. Cell. 2009 Sep 04; 138(5):834-6. Olefsky JM. PMID: 19737512.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    103. Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes. Am J Physiol Endocrinol Metab. 2009 Nov; 297(5):E1137-46. Saberi M, Bjelica D, Schenk S, Imamura T, Bandyopadhyay G, Li P, Jadhar V, Vargeese C, Wang W, Bowman K, Zhang Y, Polisky B, Olefsky JM. PMID: 19706791; PMCID: PMC2781351.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    104. FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue. Diabetes. 2009 Jun; 58(6):1275-82. Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM. PMID: 19289458; PMCID: PMC2682681.
      View in: PubMed   Mentions: 47     Fields:    Translation:Animals
    105. Discovery of imidazo[1,2-b]thiazole derivatives as novel SIRT1 activators. J Med Chem. 2009 Mar 12; 52(5):1275-83. Vu CB, Bemis JE, Disch JS, Ng PY, Nunes JJ, Milne JC, Carney DP, Lynch AV, Smith JJ, Lavu S, Lambert PD, Gagne DJ, Jirousek MR, Schenk S, Olefsky JM, Perni RB. PMID: 19199480.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    106. FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes. J Biol Chem. 2009 May 01; 284(18):12188-97. Fan W, Imamura T, Sonoda N, Sears DD, Patsouris D, Kim JJ, Olefsky JM. PMID: 19246449; PMCID: PMC2673287.
      View in: PubMed   Mentions: 64     Fields:    Translation:AnimalsCells
    107. SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. Mol Cell Biol. 2009 Mar; 29(5):1363-74. Yoshizaki T, Milne JC, Imamura T, Schenk S, Sonoda N, Babendure JL, Lu JC, Smith JJ, Jirousek MR, Olefsky JM. PMID: 19103747; PMCID: PMC2643824.
      View in: PubMed   Mentions: 195     Fields:    Translation:AnimalsCells
    108. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proc Natl Acad Sci U S A. 2008 Dec 16; 105(50):20021-6. Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, Lee CH, Evans RM. PMID: 19066220; PMCID: PMC2598729.
      View in: PubMed   Mentions: 61     Fields:    Translation:AnimalsCells
    109. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature. 2008 Nov 13; 456(7219):269-73. Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, Milne J, Meyers DJ, Cole P, Yates J, Olefsky J, Guarente L, Montminy M. PMID: 18849969; PMCID: PMC2597669.
      View in: PubMed   Mentions: 291     Fields:    Translation:HumansAnimalsCells
    110. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metab. 2008 Oct; 8(4):301-9. Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG. PMID: 18840360; PMCID: PMC2630775.
      View in: PubMed   Mentions: 418     Fields:    Translation:HumansAnimalsCells
    111. Fat talks, liver and muscle listen. Cell. 2008 Sep 19; 134(6):914-6. Olefsky JM. PMID: 18805083.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    112. Insulin sensitivity: modulation by nutrients and inflammation. J Clin Invest. 2008 Sep; 118(9):2992-3002. Schenk S, Saberi M, Olefsky JM. PMID: 18769626; PMCID: PMC2522344.
      View in: PubMed   Mentions: 471     Fields:    Translation:HumansAnimalsCells
    113. Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells. Proc Natl Acad Sci U S A. 2008 May 06; 105(18):6614-9. Sonoda N, Imamura T, Yoshizaki T, Babendure JL, Lu JC, Olefsky JM. PMID: 18445652; PMCID: PMC2373360.
      View in: PubMed   Mentions: 103     Fields:    Translation:AnimalsCells
    114. Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity. Diabetes. 2008 Jul; 57(7):1842-51. Féral CC, Neels JG, Kummer C, Slepak M, Olefsky JM, Ginsberg MH. PMID: 18426864; PMCID: PMC2453617.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    115. Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature. 2008 Feb 21; 451(7181):964-9. Yang X, Ongusaha PP, Miles PD, Havstad JC, Zhang F, So WV, Kudlow JE, Michell RH, Olefsky JM, Field SJ, Evans RM. PMID: 18288188.
      View in: PubMed   Mentions: 301     Fields:    Translation:AnimalsCells
    116. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007 Nov 29; 450(7170):712-6. Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, Westphal CH. PMID: 18046409; PMCID: PMC2753457.
      View in: PubMed   Mentions: 742     Fields:    Translation:HumansAnimalsCells
    117. Inflammation and insulin resistance. FEBS Lett. 2008 Jan 09; 582(1):97-105. de Luca C, Olefsky JM. PMID: 18053812; PMCID: PMC2246086.
      View in: PubMed   Mentions: 405     Fields:    Translation:HumansCells
    118. Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes. Mol Endocrinol. 2008 Mar; 22(3):760-71. Lu M, Tang Q, Olefsky JM, Mellon PL, Webster NJ. PMID: 18006641; PMCID: PMC2262174.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    119. JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metab. 2007 Nov; 6(5):386-97. Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M. PMID: 17983584.
      View in: PubMed   Mentions: 263     Fields:    Translation:AnimalsCells
    120. Selective modulation of promoter recruitment and transcriptional activity of PPARgamma. Biochem Biophys Res Commun. 2007 Dec 21; 364(3):515-21. Sears DD, Hsiao A, Ofrecio JM, Chapman J, He W, Olefsky JM. PMID: 17963725; PMCID: PMC2585742.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    121. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. J Biol Chem. 2007 Nov 30; 282(48):35279-92. Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. PMID: 17916553.
      View in: PubMed   Mentions: 475     Fields:    Translation:AnimalsCells
    122. Tumor necrosis factor receptor-1 can function through a G alpha q/11-beta-arrestin-1 signaling complex. J Biol Chem. 2007 Sep 28; 282(39):28549-28556. Kawamata Y, Imamura T, Babendure JL, Lu JC, Yoshizaki T, Olefsky JM. PMID: 17664271.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    123. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. J Clin Invest. 2007 Jun; 117(6):1658-69. Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. PMID: 17525798; PMCID: PMC1868788.
      View in: PubMed   Mentions: 245     Fields:    Translation:AnimalsCells
    124. Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation. Mol Cell Biol. 2007 Jul; 27(14):5172-83. Yoshizaki T, Imamura T, Babendure JL, Lu JC, Sonoda N, Olefsky JM. PMID: 17515613; PMCID: PMC1951956.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimalsCells
    125. Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E219-27. Liao W, Nguyen MT, Yoshizaki T, Favelyukis S, Patsouris D, Imamura T, Verma IM, Olefsky JM. PMID: 17389706.
      View in: PubMed   Mentions: 55     Fields:    Translation:AnimalsCells
    126. Impaired insulin secretion in a mouse model of ataxia telangiectasia. Am J Physiol Endocrinol Metab. 2007 Jul; 293(1):E70-4. Miles PD, Treuner K, Latronica M, Olefsky JM, Barlow C. PMID: 17356010.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    127. Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Nat Med. 2007 Apr; 13(4):455-62. Lesniewski LA, Hosch SE, Neels JG, de Luca C, Pashmforoush M, Lumeng CN, Chiang SH, Scadeng M, Saltiel AR, Olefsky JM. PMID: 17351624.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    128. Regulation of receptor tyrosine kinase signaling by GRKs and beta-arrestins. Annu Rev Physiol. 2007; 69:561-77. Hupfeld CJ, Olefsky JM. PMID: 17002595.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    129. The US's changing competitiveness in the biomedical sciences. J Clin Invest. 2007 Jan; 117(1):270-6. Olefsky JM. PMID: 17200723; PMCID: PMC1751294.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    130. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. Diabetes. 2006 Aug; 55(8):2277-85. Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM. PMID: 16873691.
      View in: PubMed   Mentions: 109     Fields:    Translation:HumansCells
    131. APPLied mechanics: uncovering how adiponectin modulates insulin action. Cell Metab. 2006 Jul; 4(1):5-6. Hosch SE, Olefsky JM, Kim JJ. PMID: 16814726.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    132. Cell signaling. A new way to burn fat. Science. 2006 Jun 23; 312(5781):1756-8. Neels JG, Olefsky JM. PMID: 16794069.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    133. Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes. Endocrinology. 2006 May; 147(5):2245-52. Liao W, Nguyen MT, Imamura T, Singer O, Verma IM, Olefsky JM. PMID: 16497797.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    134. PPARdelta regulates glucose metabolism and insulin sensitivity. Proc Natl Acad Sci U S A. 2006 Feb 28; 103(9):3444-9. Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. PMID: 16492734; PMCID: PMC1413918.
      View in: PubMed   Mentions: 204     Fields:    Translation:AnimalsCells
    135. Suppression of Egr-1 transcription through targeting of the serum response factor by oncogenic H-Ras. EMBO J. 2006 Mar 08; 25(5):1093-103. Shin SY, Bahk YY, Ko J, Chung IY, Lee YS, Downward J, Eibel H, Sharma PM, Olefsky JM, Kim YH, Lee B, Lee YH. PMID: 16456537; PMCID: PMC1409727.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    136. Stressed out about obesity and insulin resistance. Nat Med. 2006 Jan; 12(1):41-2; discussion 42. de Luca C, Olefsky JM. PMID: 16397561.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    137. Inflamed fat: what starts the fire? J Clin Invest. 2006 Jan; 116(1):33-5. Neels JG, Olefsky JM. PMID: 16395402; PMCID: PMC1323268.
      View in: PubMed   Mentions: 161     Fields:    Translation:HumansAnimalsCells
    138. Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem. 2005 Dec 23; 280(51):42300-6. Huang J, Imamura T, Babendure JL, Lu JC, Olefsky JM. PMID: 16239226.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    139. Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature. 2005 Sep 22; 437(7058):569-73. Zhang J, Hupfeld CJ, Taylor SS, Olefsky JM, Tsien RY. PMID: 16177793.
      View in: PubMed   Mentions: 144     Fields:    Translation:HumansAnimalsCells
    140. Synthesis and evaluation of photolabile insulin prodrugs. Bioorg Med Chem Lett. 2005 Sep 01; 15(17):3917-20. Li LS, Babendure JL, Sinha SC, Olefsky JM, Lerner RA. PMID: 15993597.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    141. JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes. J Biol Chem. 2005 Oct 21; 280(42):35361-71. Nguyen MT, Satoh H, Favelyukis S, Babendure JL, Imamura T, Sbodio JI, Zalevsky J, Dahiyat BI, Chi NW, Olefsky JM. PMID: 16085647.
      View in: PubMed   Mentions: 152     Fields:    Translation:AnimalsCells
    142. Topiramate treatment causes skeletal muscle insulin sensitization and increased Acrp30 secretion in high-fat-fed male Wistar rats. Am J Physiol Endocrinol Metab. 2005 Dec; 289(6):E1015-22. Wilkes JJ, Nguyen MT, Bandyopadhyay GK, Nelson E, Olefsky JM. PMID: 16030065.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    143. VAMPIRE microarray suite: a web-based platform for the interpretation of gene expression data. Nucleic Acids Res. 2005 Jul 01; 33(Web Server issue):W627-32. Hsiao A, Ideker T, Olefsky JM, Subramaniam S. PMID: 15980550; PMCID: PMC1160204.
      View in: PubMed   Mentions: 61     Fields:    
    144. G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes. Mol Endocrinol. 2005 Nov; 19(11):2760-8. Usui I, Imamura T, Babendure JL, Satoh H, Lu JC, Hupfeld CJ, Olefsky JM. PMID: 15994203.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    145. Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats. Diabetes. 2005 May; 54(5):1304-13. Satoh H, Nguyen MT, Trujillo M, Imamura T, Usui I, Scherer PE, Olefsky JM. PMID: 15855314.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    146. Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action. Nat Med. 2005 May; 11(5):567-71. Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS. PMID: 15821749.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    147. Variation in the gene for muscle-specific AMP deaminase is associated with insulin clearance, a highly heritable trait. Diabetes. 2005 Apr; 54(4):1222-7. Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Li X, Hang T, Yang H, Holmes E, Hsueh WA, Olefsky J, Rotter JI. PMID: 15793265.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    148. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med. 2005 Feb; 11(2):191-8. Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. PMID: 15685170.
      View in: PubMed   Mentions: 773     Fields:    Translation:AnimalsCells
    149. Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats. Am J Physiol Endocrinol Metab. 2005 Mar; 288(3):E617-24. Wilkes JJ, Nelson E, Osborne M, Demarest KT, Olefsky JM. PMID: 15536205.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    150. Insulin-induced beta-arrestin1 Ser-412 phosphorylation is a mechanism for desensitization of ERK activation by Galphai-coupled receptors. J Biol Chem. 2005 Jan 14; 280(2):1016-23. Hupfeld CJ, Resnik JL, Ugi S, Olefsky JM. PMID: 15520010.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    151. Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes. Mol Endocrinol. 2005 Feb; 19(2):421-30. Sharma PM, Son HS, Ugi S, Ricketts W, Olefsky JM. PMID: 15486046.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    152. beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1. Mol Cell Biol. 2004 Oct; 24(20):8929-37. Usui I, Imamura T, Huang J, Satoh H, Shenoy SK, Lefkowitz RJ, Hupfeld CJ, Olefsky JM. PMID: 15456867; PMCID: PMC517874.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    153. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Mol Cell Biol. 2004 Oct; 24(19):8778-89. Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM. PMID: 15367694; PMCID: PMC516764.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    154. Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13296-301. Wiedmer T, Zhao J, Li L, Zhou Q, Hevener A, Olefsky JM, Curtiss LK, Sims PJ. PMID: 15328404; PMCID: PMC516563.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    155. GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation. EMBO J. 2004 Jul 21; 23(14):2821-9. Usui I, Imamura T, Satoh H, Huang J, Babendure JL, Hupfeld CJ, Olefsky JM. PMID: 15241473; PMCID: PMC514955.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    156. Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats. J Clin Invest. 2004 Jul; 114(2):224-31. Satoh H, Nguyen MT, Miles PD, Imamura T, Usui I, Olefsky JM. PMID: 15254589; PMCID: PMC449745.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimalsCells
    157. Variance-modeled posterior inference of microarray data: detecting gene-expression changes in 3T3-L1 adipocytes. Bioinformatics. 2004 Nov 22; 20(17):3108-27. Hsiao A, Worrall DS, Olefsky JM, Subramaniam S. PMID: 15217816.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    158. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nat Med. 2004 May; 10(5):530-4. Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PMID: 15107844.
      View in: PubMed   Mentions: 240     Fields:    Translation:HumansAnimalsCells
    159. Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. J Biol Chem. 2004 May 21; 279(21):22715-26. Yoshizaki T, Maegawa H, Egawa K, Ugi S, Nishio Y, Imamura T, Kobayashi T, Tamura S, Olefsky JM, Kashiwagi A. PMID: 15016818.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    160. Annexin II is a thiazolidinedione-responsive gene involved in insulin-induced glucose transporter isoform 4 translocation in 3T3-L1 adipocytes. Endocrinology. 2004 Apr; 145(4):1579-86. Huang J, Hsia SH, Imamura T, Usui I, Olefsky JM. PMID: 14726447.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    161. Regulation of the insulin receptor by protein kinase C isoenzymes: preferential interaction with beta isoenzymes and interaction with the catalytic domain of betaII. Cell Signal. 2004 Jan; 16(1):97-104. Pillay TS, Xiao S, Keranen L, Olefsky JM. PMID: 14607280.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    162. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. J Biol Chem. 2004 Mar 26; 279(13):12152-62. Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE. PMID: 14699128.
      View in: PubMed   Mentions: 353     Fields:    Translation:HumansAnimalsCells
    163. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15712-7. He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM. PMID: 14660788; PMCID: PMC307633.
      View in: PubMed   Mentions: 449     Fields:    Translation:AnimalsCells
    164. Muscle-specific Pparg deletion causes insulin resistance. Nat Med. 2003 Dec; 9(12):1491-7. Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J. PMID: 14625542.
      View in: PubMed   Mentions: 203     Fields:    Translation:AnimalsCells
    165. Cellular effects of small molecule PTP1B inhibitors on insulin signaling. Biochemistry. 2003 Nov 11; 42(44):12792-804. Xie L, Lee SY, Andersen JN, Waters S, Shen K, Guo XL, Moller NP, Olefsky JM, Lawrence DS, Zhang ZY. PMID: 14596593.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    166. Chronic endothelin-1 treatment leads to insulin resistance in vivo. Diabetes. 2003 Aug; 52(8):1904-9. Wilkes JJ, Hevener A, Olefsky J. PMID: 12882904.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    167. Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin. Mol Cell Biol. 2003 Jul; 23(14):4892-900. Imamura T, Huang J, Usui I, Satoh H, Bever J, Olefsky JM. PMID: 12832475; PMCID: PMC162221.
      View in: PubMed   Mentions: 66     Fields:    Translation:AnimalsCells
    168. The effect of oral glucosamine sulfate on insulin sensitivity in human subjects. Diabetes Care. 2003 Jun; 26(6):1941-2. Yu JG, Boies SM, Olefsky JM. PMID: 12766141.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    169. Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets. Diabetes. 2003 Apr; 52(4):965-73. Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM. PMID: 12663468.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    170. Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. Am J Physiol Endocrinol Metab. 2003 Mar; 284(3):E618-26. Miles PD, Barak Y, Evans RM, Olefsky JM. PMID: 12556354.
      View in: PubMed   Mentions: 22     Fields:    Translation:Animals
    171. Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes. J Biol Chem. 2003 Apr 18; 278(16):13765-74. Usui I, Imamura T, Huang J, Satoh H, Olefsky JM. PMID: 12566459.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    172. Effect of obesity on susceptibility to fatty acid-induced peripheral tissue insulin resistance. Metabolism. 2003 Feb; 52(2):233-8. Kruszynska YT, Olefsky JM, Frias JP. PMID: 12601639.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    173. Beta -Arrestin 1 down-regulation after insulin treatment is associated with supersensitization of beta 2 adrenergic receptor Galpha s signaling in 3T3-L1 adipocytes. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):161-6. Hupfeld CJ, Dalle S, Olefsky JM. PMID: 12509508; PMCID: PMC140914.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    174. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes. 2002 Oct; 51(10):2968-74. Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM. PMID: 12351435.
      View in: PubMed   Mentions: 195     Fields:    Translation:HumansAnimalsCTClinical Trials
    175. Insulin induces heterologous desensitization of G-protein-coupled receptor and insulin-like growth factor I signaling by downregulating beta-arrestin-1. Mol Cell Biol. 2002 Sep; 22(17):6272-85. Dalle S, Imamura T, Rose DW, Worrall DS, Ugi S, Hupfeld CJ, Olefsky JM. PMID: 12167719; PMCID: PMC134007.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    176. Involvement of both G(q/11) and G(s) proteins in gonadotropin-releasing hormone receptor-mediated signaling in L beta T2 cells. J Biol Chem. 2002 Aug 30; 277(35):32099-108. Liu F, Usui I, Evans LG, Austin DA, Mellon PL, Olefsky JM, Webster NJ. PMID: 12050161; PMCID: PMC2930616.
      View in: PubMed   Mentions: 57     Fields:    Translation:AnimalsCells
    177. Female rats do not exhibit free fatty acid-induced insulin resistance. Diabetes. 2002 Jun; 51(6):1907-12. Hevener A, Reichart D, Janez A, Olefsky J. PMID: 12031980.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    178. Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups. Am J Hum Genet. 2002 May; 70(5):1152-71. Herrnstadt C, Elson JL, Fahy E, Preston G, Turnbull DM, Anderson C, Ghosh SS, Olefsky JM, Beal MF, Davis RE, Howell N. PMID: 11938495; PMCID: PMC447592.
      View in: PubMed   Mentions: 197     Fields:    Translation:Humans
    179. Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling. Mol Cell Biol. 2002 Apr; 22(7):2375-87. Ugi S, Imamura T, Ricketts W, Olefsky JM. PMID: 11884620; PMCID: PMC133677.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    180. Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes. J Biol Chem. 2002 May 24; 277(21):18592-7. Ugi S, Sharma PM, Ricketts W, Imamura T, Olefsky JM. PMID: 11897789.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    181. GnRH activates ERK1/2 leading to the induction of c-fos and LHbeta protein expression in LbetaT2 cells. Mol Endocrinol. 2002 Mar; 16(3):419-34. Liu F, Austin DA, Mellon PL, Olefsky JM, Webster NJ. PMID: 11875099.
      View in: PubMed   Mentions: 72     Fields:    Translation:AnimalsCells
    182. The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes. Mol Endocrinol. 2002 Feb; 16(2):378-89. Worrall DS, Olefsky JM. PMID: 11818508.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    183. Fatty acid-induced insulin resistance: decreased muscle PI3K activation but unchanged Akt phosphorylation. J Clin Endocrinol Metab. 2002 Jan; 87(1):226-34. Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM. PMID: 11788651.
      View in: PubMed   Mentions: 52     Fields:    Translation:HumansCells
    184. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proc Natl Acad Sci U S A. 2002 Jan 08; 99(1):303-8. Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R, Evans RM. PMID: 11756685; PMCID: PMC117556.
      View in: PubMed   Mentions: 196     Fields:    Translation:Animals
    185. Synthesis of an organoinsulin molecule that can be activated by antibody catalysis. Proc Natl Acad Sci U S A. 2001 Nov 20; 98(24):13514-8. Worrall DS, McDunn JE, List B, Reichart D, Hevener A, Gustafson T, Barbas CF, Lerner RA, Olefsky JM. PMID: 11707596; PMCID: PMC61072.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    186. beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport. J Biol Chem. 2001 Nov 23; 276(47):43663-7. Imamura T, Huang J, Dalle S, Ugi S, Usui I, Luttrell LM, Miller WE, Lefkowitz RJ, Olefsky JM. PMID: 11546805.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    187. Nuclear receptor minireview series. J Biol Chem. 2001 Oct 05; 276(40):36863-4. Olefsky JM. PMID: 11459855.
      View in: PubMed   Mentions: 87     Fields:    Translation:HumansAnimals
    188. Decreased susceptibility to fatty acid-induced peripheral tissue insulin resistance in women. Diabetes. 2001 Jun; 50(6):1344-50. Frias JP, Macaraeg GB, Ofrecio J, Yu JG, Olefsky JM, Kruszynska YT. PMID: 11375335.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    189. Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes. J Clin Invest. 2001 May; 107(9):1193-202. Ishibashi KI, Imamura T, Sharma PM, Huang J, Ugi S, Olefsky JM. PMID: 11342583; PMCID: PMC209278.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    190. Insulin and insulin-like growth factor I receptors utilize different G protein signaling components. J Biol Chem. 2001 May 11; 276(19):15688-95. Dalle S, Ricketts W, Imamura T, Vollenweider P, Olefsky JM. PMID: 11278773.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    191. Prospects for research in diabetes mellitus. JAMA. 2001 Feb 07; 285(5):628-32. Olefsky JM. PMID: 11176871.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    192. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling. J Biol Chem. 2001 Apr 20; 276(16):12805-12. Goalstone ML, Leitner JW, Berhanu P, Sharma PM, Olefsky JM, Draznin B. PMID: 11278505.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    193. Exercise-stimulated glucose turnover in the rat is impaired by glucosamine infusion. Diabetes. 2001 Jan; 50(1):139-42. Miles PD, Higo K, Olefsky JM. PMID: 11147779.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    194. The acute and chronic stimulatory effects of endothelin-1 on glucose transport are mediated by distinct pathways in 3T3-L1 adipocytes. Endocrinology. 2000 Dec; 141(12):4623-8. Ishibashi K, Imamura T, Sharma PM, Ugi S, Olefsky JM. PMID: 11108276.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    195. Insulin-mediated cellular insulin resistance decreases osmotic shock-induced glucose transport in 3T3-L1 adipocytes. Endocrinology. 2000 Dec; 141(12):4657-63. Janez A, Worrall DS, Olefsky JM. PMID: 11108280.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    196. Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat. Diabetes. 2000 Dec; 49(12):2154-9. Hevener AL, Reichart D, Olefsky J. PMID: 11118020.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    197. Diabetes. Gene therapy for rats and mice. Nature. 2000 Nov 23; 408(6811):420-1. Olefsky JM. PMID: 11100710.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    198. PPAR gamma and the treatment of insulin resistance. Trends Endocrinol Metab. 2000 Nov; 11(9):362-8. Olefsky JM, Saltiel AR. PMID: 11042466.
      View in: PubMed   Mentions: 73     Fields:    Translation:HumansAnimals
    199. The osmotic shock-induced glucose transport pathway in 3T3-L1 adipocytes is mediated by gab-1 and requires Gab-1-associated phosphatidylinositol 3-kinase activity for full activation. J Biol Chem. 2000 Sep 01; 275(35):26870-6. Janez A, Worrall DS, Imamura T, Sharma PM, Olefsky JM. PMID: 10842168.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    200. Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists. J Clin Invest. 2000 Aug; 106(4):467-72. Olefsky JM. PMID: 10953021; PMCID: PMC380259.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansAnimals
    201. Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes. Endocrinology. 2000 Jun; 141(6):1930-5. Egawa K, Nakashima N, Sharma PM, Maegawa H, Nagai Y, Kashiwagi A, Kikkawa R, Olefsky JM. PMID: 10830273.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    202. A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. Mol Endocrinol. 2000 Jun; 14(6):783-94. Haruta T, Uno T, Kawahara J, Takano A, Egawa K, Sharma PM, Olefsky JM, Kobayashi M. PMID: 10847581.
      View in: PubMed   Mentions: 177     Fields:    Translation:HumansAnimalsCells
    203. The tumor suppressor PTEN negatively regulates insulin signaling in 3T3-L1 adipocytes. J Biol Chem. 2000 Apr 28; 275(17):12889-95. Nakashima N, Sharma PM, Imamura T, Bookstein R, Olefsky JM. PMID: 10777587.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    204. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology. 2000 Apr; 141(4):1310-6. Draznin B, Miles P, Kruszynska Y, Olefsky J, Friedman J, Golovchenko I, Stjernholm R, Wall K, Reitman M, Accili D, Cooksey R, McClain D, Goalstone M. PMID: 10746633.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    205. Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects. Diabetes. 2000 Apr; 49(4):633-9. Kruszynska YT, Yu JG, Olefsky JM, Sobel BE. PMID: 10871202.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    206. Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. J Clin Invest. 2000 Feb; 105(3):287-92. Miles PD, Barak Y, He W, Evans RM, Olefsky JM. PMID: 10675354; PMCID: PMC377448.
      View in: PubMed   Mentions: 114     Fields:    Translation:Animals
    207. Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects. Diabetes Care. 2000 Jan; 23(1):64-9. Frias JP, Yu JG, Kruszynska YT, Olefsky JM. PMID: 10857970.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    208. A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients. Diabetes. 1999 Dec; 48(12):2414-21. Yu JG, Kruszynska YT, Mulford MI, Olefsky JM. PMID: 10580431.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCTClinical Trials
    209. Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways. Mol Endocrinol. 1999 Dec; 13(12):1988-2001. Ricketts WA, Brown JH, Olefsky JM. PMID: 10598576.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    210. Endothelin-1-induced GLUT4 translocation is mediated via Galpha(q/11) protein and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. J Biol Chem. 1999 Nov 19; 274(47):33691-5. Imamura T, Ishibashi K, Dalle S, Ugi S, Olefsky JM. PMID: 10559259.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    211. G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes. Mol Cell Biol. 1999 Oct; 19(10):6765-74. Imamura T, Vollenweider P, Egawa K, Clodi M, Ishibashi K, Nakashima N, Ugi S, Adams JW, Brown JH, Olefsky JM. PMID: 10490615; PMCID: PMC84673.
      View in: PubMed   Mentions: 41     Fields:    Translation:AnimalsCells
    212. Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells. Oncogene. 1999 Sep 02; 18(35):4908-19. Zapf-Colby A, Eichhorn J, Webster NJ, Olefsky JM. PMID: 10490825.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    213. Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance. J Biol Chem. 1999 May 14; 274(20):14306-14. Egawa K, Sharma PM, Nakashima N, Huang Y, Huver E, Boss GR, Olefsky JM. PMID: 10318852.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    214. An SH2 domain-containing 5' inositolphosphatase inhibits insulin-induced GLUT4 translocation and growth factor-induced actin filament rearrangement. Mol Cell Biol. 1999 Feb; 19(2):1081-91. Vollenweider P, Clodi M, Martin SS, Imamura T, Kavanaugh WM, Olefsky JM. PMID: 9891043; PMCID: PMC116038.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    215. The functional role of CrkII in actin cytoskeleton organization and mitogenesis. J Biol Chem. 1999 Jan 29; 274(5):3001-8. Nakashima N, Rose DW, Xiao S, Egawa K, Martin SS, Haruta T, Saltiel AR, Olefsky JM. PMID: 9915838.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    216. Insulin-stimulated glucose transport minireview series. J Biol Chem. 1999 Jan 22; 274(4):1863. Olefsky JM. PMID: 9890934.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    217. Effects of general receptor for phosphoinositides 1 on insulin and insulin-like growth factor I-induced cytoskeletal rearrangement, glucose transporter-4 translocation, and deoxyribonucleic acid synthesis. Endocrinology. 1998 Dec; 139(12):4984-90. Clodi M, Vollenweider P, Klarlund J, Nakashima N, Martin S, Czech MP, Olefsky JM. PMID: 9832437.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    218. Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport. J Biol Chem. 1998 Sep 25; 273(39):25139-47. Staubs PA, Nelson JG, Reichart DR, Olefsky JM. PMID: 9737973.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    219. Prolonged vs transient roles for early cell cycle signaling components. Oncogene. 1998 Aug 20; 17(7):889-99. Rose DW, Xiao S, Pillay TS, Kolch W, Olefsky JM. PMID: 9780005.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    220. Lack of insulin resistance in fibroblasts from subjects with polycystic ovary syndrome. Metabolism. 1998 Aug; 47(8):940-6. Ciaraldi TP, Morales AJ, Hickman MG, Odom-Ford R, Yen SS, Olefsky JM. PMID: 9711989.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    221. Inhibition of phosphatidylinositol 3-kinase activity by adenovirus-mediated gene transfer and its effect on insulin action. J Biol Chem. 1998 Jul 17; 273(29):18528-37. Sharma PM, Egawa K, Huang Y, Martin JL, Huvar I, Boss GR, Olefsky JM. PMID: 9660823.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    222. Nerve growth factor processing and trafficking events following TrkA-mediated endocytosis. Endocrinology. 1998 Jul; 139(7):3232-40. Zapf-Colby A, Olefsky JM. PMID: 9645698.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    223. Regulation of skeletal muscle hexokinase II by insulin in nondiabetic and NIDDM subjects. Diabetes. 1998 Jul; 47(7):1107-13. Kruszynska YT, Mulford MI, Baloga J, Yu JG, Olefsky JM. PMID: 9648835.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    224. Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin. J Biol Chem. 1998 May 29; 273(22):13808-18. Kayali AG, Eichhorn J, Haruta T, Morris AJ, Nelson JG, Vollenweider P, Olefsky JM, Webster NJ. PMID: 9593725.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    225. Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology and SH2 domains. J Biol Chem. 1998 Mar 20; 273(12):6860-7. He W, Rose DW, Olefsky JM, Gustafson TA. PMID: 9506989.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    226. Troglitazone prevents hyperglycemia-induced but not glucosamine-induced insulin resistance. Diabetes. 1998 Mar; 47(3):395-400. Miles PD, Higo K, Romeo OM, Lee MK, Rafaat K, Olefsky JM. PMID: 9519745.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    227. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Ann Intern Med. 1998 Feb 01; 128(3):176-85. Maggs DG, Buchanan TA, Burant CF, Cline G, Gumbiner B, Hsueh WA, Inzucchi S, Kelley D, Nolan J, Olefsky JM, Polonsky KS, Silver D, Valiquett TR, Shulman GI. PMID: 9454525.
      View in: PubMed   Mentions: 64     Fields:    Translation:HumansCTClinical Trials
    228. Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus. J Clin Invest. 1998 Feb 01; 101(3):543-8. Kruszynska YT, Mukherjee R, Jow L, Dana S, Paterniti JR, Olefsky JM. PMID: 9449686; PMCID: PMC508596.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    229. Ligand-independent GLUT4 translocation induced by guanosine 5'-O-(3-thiotriphosphate) involves tyrosine phosphorylation. Endocrinology. 1998 Jan; 139(1):358-64. Haruta T, Morris AJ, Vollenweider P, Nelson JG, Rose DW, Mueckler M, Olefsky JM. PMID: 9421434.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    230. Mechanisms of insulin resistance in experimental hyperinsulinemic dogs. J Clin Invest. 1998 Jan 01; 101(1):202-11. Miles PD, Li S, Hart M, Romeo O, Cheng J, Cohen A, Raafat K, Moossa AR, Olefsky JM. PMID: 9421483; PMCID: PMC508557.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    231. Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes. Mol Cell Biol. 1997 Dec; 17(12):7386-97. Sharma PM, Egawa K, Gustafson TA, Martin JL, Olefsky JM. PMID: 9372969; PMCID: PMC232594.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    232. Evidence for decreased splanchnic glucose uptake after oral glucose administration in non-insulin-dependent diabetes mellitus. J Clin Invest. 1997 Nov 01; 100(9):2354-61. Ludvik B, Nolan JJ, Roberts A, Baloga J, Joyce M, Bell JM, Olefsky JM. PMID: 9410915; PMCID: PMC508433.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    233. TNF-alpha-induced insulin resistance in vivo and its prevention by troglitazone. Diabetes. 1997 Nov; 46(11):1678-83. Miles PD, Romeo OM, Higo K, Cohen A, Rafaat K, Olefsky JM. PMID: 9356012.
      View in: PubMed   Mentions: 27     Fields:    Translation:Animals
    234. The small guanosine triphosphate-binding protein Rab4 is involved in insulin-induced GLUT4 translocation and actin filament rearrangement in 3T3-L1 cells. Endocrinology. 1997 Nov; 138(11):4941-9. Vollenweider P, Martin SS, Haruta T, Morris AJ, Nelson JG, Cormont M, Le Marchand-Brustel Y, Rose DW, Olefsky JM. PMID: 9348225.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    235. Effects of nonesterified fatty acids on glucose metabolism after glucose ingestion. Diabetes. 1997 Oct; 46(10):1586-93. Kruszynska YT, Mulford MI, Yu JG, Armstrong DA, Olefsky JM. PMID: 9313754.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    236. The G12 coupled thrombin receptor stimulates mitogenesis through the Shc SH2 domain. Oncogene. 1997 Jul 31; 15(5):595-600. Collins LR, Ricketts WA, Olefsky JM, Brown JH. PMID: 9247313.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    237. Mechanisms of the kinetic defect in insulin action in obesity and NIDDM. Diabetes. 1997 Jun; 46(6):994-1000. Nolan JJ, Ludvik B, Baloga J, Reichart D, Olefsky JM. PMID: 9166671.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    238. Amylin release during oral glucose tolerance test. Diabet Med. 1997 Jun; 14 Suppl 2:S29-34. Thomaseth K, Pacini G, Clodi M, Kautzky-Willer A, Nolan JJ, Prager R, Olefsky JM, Ludvik B. PMID: 9212327.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    239. Cellular insulin resistance in adipocytes from obese polycystic ovary syndrome subjects involves adenosine modulation of insulin sensitivity. J Clin Endocrinol Metab. 1997 May; 82(5):1421-5. Ciaraldi TP, Morales AJ, Hickman MG, Odom-Ford R, Olefsky JM, Yen SS. PMID: 9141527.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    240. The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway. J Biol Chem. 1997 Feb 07; 272(6):3780-7. Ojaniemi M, Martin SS, Dolfi F, Olefsky JM, Vuori K. PMID: 9013636.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    241. Thiazolidinediones in the treatment of insulin resistance and type II diabetes. Diabetes. 1996 Dec; 45(12):1661-9. Saltiel AR, Olefsky JM. PMID: 8922349.
      View in: PubMed   Mentions: 184     Fields:    Translation:HumansAnimals
    242. Phosphatidylinositol 3-kinase is necessary and sufficient for insulin-stimulated stress fiber breakdown. Endocrinology. 1996 Nov; 137(11):5045-54. Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM. PMID: 8895379.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    243. Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling. J Biol Chem. 1996 Oct 18; 271(42):26165-9. Ricketts WA, Rose DW, Shoelson S, Olefsky JM. PMID: 8824262.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    244. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways. Endocrinology. 1996 Oct; 137(10):4427-34. Sasaoka T, Ishiki M, Sawa T, Ishihara H, Takata Y, Imamura T, Usui I, Olefsky JM, Kobayashi M. PMID: 8828504.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    245. Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus. J Investig Med. 1996 Oct; 44(8):413-28. Kruszynska YT, Olefsky JM. PMID: 8952222.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    246. Protein tyrosine phosphatase 1B interacts with the activated insulin receptor. Diabetes. 1996 Oct; 45(10):1379-85. Seely BL, Staubs PA, Reichart DR, Berhanu P, Milarski KL, Saltiel AR, Kusari J, Olefsky JM. PMID: 8826975.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    247. Interaction of a GRB-IR splice variant (a human GRB10 homolog) with the insulin and insulin-like growth factor I receptors. Evidence for a role in mitogenic signaling. J Biol Chem. 1996 Sep 13; 271(37):22506-13. O'Neill TJ, Rose DW, Pillay TS, Hotta K, Olefsky JM, Gustafson TA. PMID: 8798417.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    248. Effect of troglitazone on leptin production. Studies in vitro and in human subjects. Diabetes. 1996 Sep; 45(9):1276-8. Nolan JJ, Olefsky JM, Nyce MR, Considine RV, Caro JF. PMID: 8772734.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    249. Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling. J Biol Chem. 1996 Aug 16; 271(33):19810-6. Kenner KA, Anyanwu E, Olefsky JM, Kusari J. PMID: 8702689.
      View in: PubMed   Mentions: 87     Fields:    Translation:AnimalsCells
    250. Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8401-6. Morris AJ, Martin SS, Haruta T, Nelson JG, Vollenweider P, Gustafson TA, Mueckler M, Rose DW, Olefsky JM. PMID: 8710883; PMCID: PMC38683.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    251. Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. J Biol Chem. 1996 Jul 26; 271(30):17605-8. Martin SS, Haruta T, Morris AJ, Klippel A, Williams LT, Olefsky JM. PMID: 8663595.
      View in: PubMed   Mentions: 56     Fields:    Translation:AnimalsCells
    252. Expression of dominant negative mutant SHPTP2 attenuates phosphatidylinositol 3'-kinase activity via modulation of phosphorylation of insulin receptor substrate-1. J Biol Chem. 1996 May 24; 271(21):12595-602. Ugi S, Maegawa H, Kashiwagi A, Adachi M, Olefsky JM, Kikkawa R. PMID: 8647870.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    253. Acute and chronic effects of insulin on leptin production in humans: Studies in vivo and in vitro. Diabetes. 1996 May; 45(5):699-701. Kolaczynski JW, Nyce MR, Considine RV, Boden G, Nolan JJ, Henry R, Mudaliar SR, Olefsky J, Caro JF. PMID: 8621027.
      View in: PubMed   Mentions: 83     Fields:    Translation:HumansCells
    254. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites. J Biol Chem. 1996 Apr 05; 271(14):8338-44. Sasaoka T, Langlois WJ, Bai F, Rose DW, Leitner JW, Decker SJ, Saltiel A, Gill GN, Kobayashi M, Draznin B, Olefsky JM. PMID: 8626530.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    255. Glucose-induced phosphorylation of the insulin receptor. Functional effects and characterization of phosphorylation sites. J Clin Invest. 1996 Feb 01; 97(3):613-20. Pillay TS, Xiao S, Olefsky JM. PMID: 8609215; PMCID: PMC507096.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    256. Insulin-stimulated GLUT4 translocation is mediated by a divergent intracellular signaling pathway. J Biol Chem. 1995 Nov 24; 270(47):27991-4. Haruta T, Morris AJ, Rose DW, Nelson JG, Mueckler M, Olefsky JM. PMID: 7499278.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    257. Metabolic effects of troglitazone on fat-induced insulin resistance in the rat. Metabolism. 1995 Nov; 44(11):1489-94. Khoursheed M, Miles PD, Gao KM, Lee MK, Moossa AR, Olefsky JM. PMID: 7476339.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    258. Negative feedback regulation and desensitization of insulin- and epidermal growth factor-stimulated p21ras activation. J Biol Chem. 1995 Oct 27; 270(43):25320-3. Langlois WJ, Sasaoka T, Saltiel AR, Olefsky JM. PMID: 7592690.
      View in: PubMed   Mentions: 57     Fields:    Translation:HumansAnimalsCells
    259. Acute effects of troglitazone on in vivo insulin action in normal rats. Metabolism. 1995 Sep; 44(9):1166-9. Lee MK, Olefsky JM. PMID: 7666790.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    260. Effect of obesity on insulin resistance in normal subjects and patients with NIDDM. Diabetes. 1995 Sep; 44(9):1121-5. Ludvik B, Nolan JJ, Baloga J, Sacks D, Olefsky J. PMID: 7657038.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    261. Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein. J Biol Chem. 1995 Aug 11; 270(32):19151-7. Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, Olefsky JM. PMID: 7642582.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    262. Regulation of glucose transport in cultured muscle cells by novel hypoglycemic agents. Metabolism. 1995 Aug; 44(8):976-81. Ciaraldi TP, Huber-Knudsen K, Hickman M, Olefsky JM. PMID: 7637655.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    263. Kinetics of insulin action in vivo. Identification of rate-limiting steps. Diabetes. 1995 Aug; 44(8):947-53. Miles PD, Levisetti M, Reichart D, Khoursheed M, Moossa AR, Olefsky JM. PMID: 7622001.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    264. Mechanism of activation of guanine nucleotide exchange factor by insulin. Endocrine. 1995 Jul; 3(7):475-9. Langlois J, Leitner W, Medh J, Sasaoka T, Olefsky JM, Draznin B. PMID: 21153201.
      View in: PubMed   Mentions:    Fields:    
    265. Signal transduction pathways leading to insulin-induced early gene induction. Biochemistry. 1995 Jun 27; 34(25):7996-8004. Jhun BH, Haruta T, Meinkoth JL, Leitner W, Draznin B, Saltiel AR, Pang L, Sasaoka T, Olefsky JM. PMID: 7540866.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    266. Insulin inhibits nuclear phosphatase activity: requirement for the C-terminal domain of the insulin receptor. Endocrinology. 1995 Jun; 136(6):2464-9. Reusch JE, Hsieh P, Bhuripanyo P, Carel K, Leitner JW, Olefsky JM, Draznin B. PMID: 7750468.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    267. Weighing in on the lean genes. J Clin Invest. 1995 Jun; 95(6):2427-8. Olefsky JM. PMID: 7769085; PMCID: PMC295909.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    268. Mechanisms of enhanced transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain. J Biol Chem. 1995 May 05; 270(18):10885-92. Sasaoka T, Langlois WJ, Rose DW, Olefsky JM. PMID: 7738028.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    269. A noninvasive method to measure splanchnic glucose uptake after oral glucose administration. J Clin Invest. 1995 May; 95(5):2232-8. Ludvik B, Nolan JJ, Roberts A, Baloga J, Joyce M, Bell JM, Olefsky JM. PMID: 7738188; PMCID: PMC295835.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    270. Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild type insulin-like growth factor 1 or insulin receptors. Endocrinology. 1995 May; 136(5):1978-86. Langlois WJ, Sasaoka T, Yip CC, Olefsky JM. PMID: 7720646.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    271. Insulin resistance and non-insulin-dependent diabetes mellitus: cellular and molecular mechanisms. Am J Clin Nutr. 1995 04; 61(4 Suppl):980S-986S. Olefsky JM, Nolan JJ. PMID: 7900697.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    272. A functional assessment of insulin/insulin-like growth factor-I hybrid receptors. Endocrinology. 1995 Apr; 136(4):1635-41. Seely BL, Reichart DR, Takata Y, Yip C, Olefsky JM. PMID: 7895674.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    273. Insulin stimulates the tyrosine dephosphorylation of pp125 focal adhesion kinase. J Biol Chem. 1995 Jan 20; 270(3):991-4. Pillay TS, Sasaoka T, Olefsky JM. PMID: 7836419.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    274. The genetics of non-insulin-dependent diabetes mellitus. Adv Genet. 1995; 32:51-98. Pillay TS, Langlois WJ, Olefsky JM. PMID: 7741025.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    275. The signaling pathway coupling epidermal growth factor receptors to activation of p21ras. J Biol Chem. 1994 Dec 23; 269(51):32621-5. Sasaoka T, Langlois WJ, Leitner JW, Draznin B, Olefsky JM. PMID: 7798267.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    276. Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms. Endocrinology. 1994 Dec; 135(6):2412-7. Langlois WJ, Medh J, Leitner JW, Sasaoka T, Olefsky JM, Draznin B. PMID: 7988425.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    277. Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat. Diabetes. 1994 Dec; 43(12):1435-9. Lee MK, Miles PD, Khoursheed M, Gao KM, Moossa AR, Olefsky JM. PMID: 7958495.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    278. Localization of the insulin receptor binding sites for the SH2 domain proteins p85, Syp, and GAP. J Biol Chem. 1994 Nov 04; 269(44):27186-92. Staubs PA, Reichart DR, Saltiel AR, Milarski KL, Maegawa H, Berhanu P, Olefsky JM, Seely BL. PMID: 7525547.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    279. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med. 1994 Nov 03; 331(18):1188-93. Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J. PMID: 7935656.
      View in: PubMed   Mentions: 196     Fields:    Translation:HumansCTClinical Trials
    280. Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression. Mol Cell Biol. 1994 Nov; 14(11):7466-75. Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM. PMID: 7935461; PMCID: PMC359282.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    281. Islet amyloid polypeptide (amylin) increases the renal excretion of calcium in the conscious dog. Calcif Tissue Int. 1994 Oct; 55(4):269-73. Miles PD, Deftos LJ, Moossa AR, Olefsky JM. PMID: 7820778.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    282. Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J Biol Chem. 1994 Aug 19; 269(33):21244-8. Xiao S, Rose DW, Sasaoka T, Maegawa H, Burke TR, Roller PP, Shoelson SE, Olefsky JM. PMID: 8063747.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    283. Hybrid formation between endogenous mouse and transfected human tyrosine kinase-deficient (A/K1018) insulin receptors leads to decreased insulin sensitivity in 3T3-L1 adipocytes. Mol Endocrinol. 1994 Jun; 8(6):682-92. Grako KA, McClain DA, Olefsky JM. PMID: 7935484.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    284. Comparison of the intracellular itineraries of insulin-like growth factor-I and insulin and their receptors in Rat-1 fibroblasts. Endocrinology. 1994 Jun; 134(6):2445-52. Zapf A, Hsu D, Olefsky JM. PMID: 8194471.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    285. Evidence for a functional role of Shc proteins in mitogenic signaling induced by insulin, insulin-like growth factor-1, and epidermal growth factor. J Biol Chem. 1994 May 06; 269(18):13689-94. Sasaoka T, Rose DW, Jhun BH, Saltiel AR, Draznin B, Olefsky JM. PMID: 7513704.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansAnimalsCells
    286. Mutation of the two carboxyl-terminal tyrosines in the insulin receptor results in enhanced activation of mitogen-activated protein kinase. J Biol Chem. 1994 Apr 08; 269(14):10604-8. Pang L, Milarski KL, Ohmichi M, Takata Y, Olefsky JM, Saltiel AR. PMID: 8144649.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    287. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. J Biol Chem. 1994 Apr 08; 269(14):10734-8. Sasaoka T, Draznin B, Leitner JW, Langlois WJ, Olefsky JM. PMID: 8144662.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    288. Src homology 2 domains of protein tyrosine phosphatase are associated in vitro with both the insulin receptor and insulin receptor substrate-1 via different phosphotyrosine motifs. FEBS Lett. 1994 Mar 07; 340(3):216-20. Ugi S, Maegawa H, Olefsky JM, Shigeta Y, Kashiwagi A. PMID: 7510639.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    289. Insulin and insulin-like growth factor-I signal transduction requires p21ras. J Biol Chem. 1994 Feb 25; 269(8):5699-704. Jhun BH, Meinkoth JL, Leitner JW, Draznin B, Olefsky JM. PMID: 8119907.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    290. NPXY motif in the insulin-like growth factor-I receptor is required for efficient ligand-mediated receptor internalization and biological signaling. Endocrinology. 1994 Feb; 134(2):744-50. Hsu D, Knudson PE, Zapf A, Rolband GC, Olefsky JM. PMID: 8299569.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    291. Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity. J Clin Endocrinol Metab. 1994 Feb; 78(2):471-7. Nolan JJ, Freidenberg G, Henry R, Reichart D, Olefsky JM. PMID: 8106637.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    292. Mechanisms of cellular insulin resistance in human pregnancy. Am J Obstet Gynecol. 1994 Feb; 170(2):635-41. Ciaraldi TP, Kettel M, el-Roeiy A, Madar Z, Reichart D, Yen SS, Olefsky JM. PMID: 8116725.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    293. Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction. Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2):797-801. Rose DW, Saltiel AR, Majumdar M, Decker SJ, Olefsky JM. PMID: 8290602; PMCID: PMC43036.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    294. Delayed onset of insulin activation of the insulin receptor kinase in vivo in human skeletal muscle. Diabetes. 1994 Jan; 43(1):118-26. Freidenberg GR, Suter S, Henry RR, Nolan J, Reichart D, Olefsky JM. PMID: 8262308.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    295. Deletion of exon 21 of the insulin receptor eliminates tyrosine kinase activity but preserves mitogenic signaling. Biochemistry. 1993 Dec 14; 32(49):13545-50. Rolband GC, Williams JF, Webster NJ, Hsu D, Olefsky JM. PMID: 8257690.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    296. Regulation of protein tyrosine phosphatases by insulin and insulin-like growth factor I. J Biol Chem. 1993 Dec 05; 268(34):25455-62. Kenner KA, Hill DE, Olefsky JM, Kusari J. PMID: 8244979.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    297. Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes. Endocrinology. 1993 Dec; 133(6):2943-50. Karnieli E, Garvey WT, Olefsky JM, Hueckstead TP, Harel C, Maianu L, Armoni M. PMID: 8243322.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    298. Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors. J Biol Chem. 1993 Sep 25; 268(27):19998-20001. Draznin B, Chang L, Leitner JW, Takata Y, Olefsky JM. PMID: 8376360.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    299. The insulin receptor C-terminus is involved in regulation of the receptor kinase activity. Biochemistry. 1993 Sep 21; 32(37):9539-44. Kaliman P, Baron V, Alengrin F, Takata Y, Webster NJ, Olefsky JM, Van Obberghen E. PMID: 7690586.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    300. Deletion of the insulin receptor beta-subunit acidic domain results in enhanced metabolic signaling. Endocrinology. 1993 Sep; 133(3):1437-43. Rolband GC, Williams JF, Webster NJ, Olefsky JM. PMID: 8396020.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    301. Effect of a major histocompatibility complex class I peptide on insulin-like growth factor-I receptor internalization and biological signaling. Endocrinology. 1993 Sep; 133(3):1247-51. Hsu D, Olefsky JM. PMID: 8365366.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    302. Insulin-responsive human adipocytes express two glucose transporter isoforms and target them to different vesicles. J Clin Endocrinol Metab. 1993 Jul; 77(1):286-9. Pilch PF, Wilkinson W, Garvey WT, Ciaraldi TP, Hueckstaedt TP, Olefsky JM. PMID: 8325954.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    303. Transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4379-83. Sasaoka T, Takata Y, Kusari J, Anderson CM, Langlois WJ, Olefsky JM. PMID: 8506276; PMCID: PMC46514.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    304. Relative expression of insulin receptor isoforms does not differ in lean, obese, and noninsulin-dependent diabetes mellitus subjects. J Clin Endocrinol Metab. 1993 May; 76(5):1380-2. Anderson CM, Henry RR, Knudson PE, Olefsky JM, Webster NJ. PMID: 7684396.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    305. Mechanism of impaired metabolic signaling by a truncated human insulin receptor. Decreased activation of protein phosphatase 1 by insulin. J Biol Chem. 1993 Apr 15; 268(11):7917-22. Begum N, Olefsky JM, Draznin B. PMID: 8385127.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    306. A truncated human insulin receptor missing the COOH-terminal 365 amino acid residues does not undergo insulin-mediated receptor migration or aggregation. Endocrinology. 1993 Apr; 132(4):1453-62. Smith RM, Sasaoka T, Shah N, Takata Y, Kusari J, Olefsky JM, Jarett L. PMID: 8462446.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    307. Preparation of N epsilon B28-monoazidobenzoyl insulin-like growth factor I and photoaffinity labeling of insulin-like growth factor I receptor. Peptides. 1993 Mar-Apr; 14(2):325-30. Yip CC, Hsu H, Olefsky JM, Seely L. PMID: 8483809.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    308. Insulin resistance and the pathogenesis of non-insulin dependent diabetes mellitus: cellular and molecular mechanisms. Adv Exp Med Biol. 1993; 334:129-50. Olefsky JM. PMID: 8249678.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    309. Characterization of insulin-like growth factor (IGF) binding proteins and their role in modulating IGF-I action in BHK cells. J Biol Chem. 1992 Dec 15; 267(35):25576-82. Hsu D, Olefsky JM. PMID: 1281161.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    310. Cellular mechanisms of insulin resistance in polycystic ovarian syndrome. J Clin Endocrinol Metab. 1992 Aug; 75(2):577-83. Ciaraldi TP, el-Roeiy A, Madar Z, Reichart D, Olefsky JM, Yen SS. PMID: 1322430.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    311. Evidence that glucose transport is rate-limiting for in vivo glucose uptake. Metabolism. 1992 Aug; 41(8):897-902. Fink RI, Wallace P, Brechtel G, Olefsky JM. PMID: 1640870.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    312. Tyrosine kinase-defective insulin receptors undergo decreased endocytosis but do not affect internalization of normal endogenous insulin receptors. Endocrinology. 1992 Jun; 130(6):3441-52. Grako KA, Olefsky JM, McClain DA. PMID: 1317784.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    313. Intracellular signaling by a mutant human insulin receptor lacking the carboxyl-terminal tyrosine autophosphorylation sites. J Biol Chem. 1992 May 05; 267(13):9065-70. Takata Y, Webster NJ, Olefsky JM. PMID: 1577744.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    314. Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care. 1992 Feb; 15(2):193-203. Suter SL, Nolan JJ, Wallace P, Gumbiner B, Olefsky JM. PMID: 1547676.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansCells
    315. Phorbol ester-mediated protein kinase C interaction with wild-type and COOH-terminal truncated insulin receptors. J Biol Chem. 1991 Nov 15; 266(32):21760-4. Anderson CM, Olefsky JM. PMID: 1657981.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    316. Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus. J Clin Invest. 1991 Oct; 88(4):1323-30. Kusari J, Verma US, Buse JB, Henry RR, Olefsky JM. PMID: 1918382; PMCID: PMC295602.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    317. Contribution of postprandial insulin and glucose to glucose disposal in normal and insulin-resistant obese subjects. J Clin Endocrinol Metab. 1991 Oct; 73(4):758-64. Klauser R, Prager R, Schernthaner G, Olefsky JM. PMID: 1890150.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    318. Tyrosine kinase-defective insulin receptors undergo insulin-induced microaggregation but do not concentrate in coated pits. J Biol Chem. 1991 Sep 15; 266(26):17522-30. Smith RM, Seely BL, Shah N, Olefsky JM, Jarett L. PMID: 1910046.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    319. Lack of effect of islet amyloid polypeptide in causing insulin resistance in conscious dogs during euglycemic clamp studies. Diabetes. 1991 Aug; 40(8):998-1004. Kassir AA, Upadhyay AK, Lim TJ, Moossa AR, Olefsky JM. PMID: 1860564.
      View in: PubMed   Mentions: 9     Fields:    Translation:Animals
    320. In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies. J Clin Invest. 1991 Jun; 87(6):2222-9. Freidenberg GR, Suter SL, Henry RR, Reichart D, Olefsky JM. PMID: 1645756; PMCID: PMC296983.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    321. Mutation of the two carboxyl-terminal tyrosines results in an insulin receptor with normal metabolic signaling but enhanced mitogenic signaling properties. J Biol Chem. 1991 May 15; 266(14):9135-9. Takata Y, Webster NJ, Olefsky JM. PMID: 2026614.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    322. Insulin action kinetics in adipocytes from obese and noninsulin-dependent diabetes mellitus subjects: identification of multiple cellular defects in glucose transport. J Clin Endocrinol Metab. 1991 Apr; 72(4):876-82. Ciaraldi TP, Molina JM, Olefsky JM. PMID: 2005215.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    323. Insulin resistance and diabetes due to different mutations in the tyrosine kinase domain of both insulin receptor gene alleles. J Biol Chem. 1991 Mar 15; 266(8):5260-7. Kusari J, Takata Y, Hatada E, Freidenberg G, Kolterman O, Olefsky JM. PMID: 2002058.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    324. Insulin-receptor cDNA sequence in NIDDM patient homozygous for insulin-receptor gene RFLP. Diabetes. 1991 Feb; 40(2):249-54. Kusari J, Olefsky JM, Strahl C, McClain DA. PMID: 1671379.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    325. Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors. Proc Natl Acad Sci U S A. 1991 Jan 01; 88(1):214-8. Treadway JL, Morrison BD, Soos MA, Siddle K, Olefsky J, Ullrich A, McClain DA, Pessin JE. PMID: 1846039; PMCID: PMC50780.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    326. In vitro studies on the action of CS-045, a new antidiabetic agent. Metabolism. 1990 Oct; 39(10):1056-62. Ciaraldi TP, Gilmore A, Olefsky JM, Goldberg M, Heidenreich KA. PMID: 2120548.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    327. Defective insulin receptor function in down-regulated HepG2 cells. Endocrinology. 1990 Oct; 127(4):1706-17. Williams JF, Olefsky JM. PMID: 2169397.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    328. The insulin receptor. A multifunctional protein. Diabetes. 1990 Sep; 39(9):1009-16. Olefsky JM. PMID: 2166696.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    329. Kinetics of insulin-mediated and non-insulin-mediated glucose uptake in humans. Diabetes. 1990 Aug; 39(8):955-64. Edelman SV, Laakso M, Wallace P, Brechtel G, Olefsky JM, Baron AD. PMID: 1973673.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    330. Kinetics of in vivo muscle insulin-mediated glucose uptake in human obesity. Diabetes. 1990 Aug; 39(8):965-74. Laakso M, Edelman SV, Olefsky JM, Brechtel G, Wallace P, Baron AD. PMID: 2197140.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    331. The ligand binding characteristics of a kinase-defective A/K1018 human insulin receptor expressed in Rat 1 fibroblasts. Biochim Biophys Acta. 1990 Jul 12; 1053(2-3):185-8. Maegawa H, Kobayashi M, Egawa K, McClain DA, Olefsky JM, Shigeta Y. PMID: 2200525.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    332. Characterization of an insulin receptor mutant lacking the subunit processing site. J Biol Chem. 1990 May 25; 265(15):8463-9. Williams JF, McClain DA, Dull TJ, Ullrich A, Olefsky JM. PMID: 2187866.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    333. Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects. Diabetes. 1990 Feb; 39(2):250-9. Thies RS, Molina JM, Ciaraldi TP, Freidenberg GR, Olefsky JM. PMID: 2227134.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    334. Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide. Diabetes. 1990 Feb; 39(2):260-5. Molina JM, Cooper GJ, Leighton B, Olefsky JM. PMID: 2227135.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    335. Dissection of the growth versus metabolic effects of insulin and insulin-like growth factor-I in transfected cells expressing kinase-defective human insulin receptors. J Biol Chem. 1990 Jan 25; 265(3):1678-82. McClain DA, Maegawa H, Thies RS, Olefsky JM. PMID: 2153140.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    336. Use of a variable tracer infusion method to determine glucose turnover in humans. Am J Physiol. 1990 Jan; 258(1 Pt 1):E16-23. Molina JM, Baron AD, Edelman SV, Brechtel G, Wallace P, Olefsky JM. PMID: 2405697.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    337. Decreased activation rate of insulin-stimulated glucose transport in adipocytes from obese subjects. Diabetes. 1989 Aug; 38(8):991-5. Molina JM, Ciaraldi TP, Brady D, Olefsky JM. PMID: 2666204.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    338. Effects of growth and insulin treatment on the levels of insulin receptors and their mRNA in Hep G2 cells. J Biol Chem. 1989 Apr 25; 264(12):6741-7. Hatada EN, McClain DA, Potter E, Ullrich A, Olefsky JM. PMID: 2540160.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    339. Mechanism of defective insulin-receptor kinase activity in NIDDM. Evidence for two receptor populations. Diabetes. 1989 Mar; 38(3):397-403. Brillon DJ, Freidenberg GR, Henry RR, Olefsky JM. PMID: 2465197.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    340. Cellular mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes. Am J Med. 1988 Nov 28; 85(5A):86-105. Olefsky JM, Garvey WT, Henry RR, Brillon D, Matthaei S, Freidenberg GR. PMID: 3057897.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    341. Functional and structural differences in human and rat-derived insulin receptors: characterization of the beta-subunit kinase activity. Endocrinology. 1988 Oct; 123(4):1837-47. Brillon DJ, Henry RR, Klein HH, Olefsky JM, Freidenberg GR. PMID: 2843349.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    342. Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss. J Clin Invest. 1988 Oct; 82(4):1398-406. Freidenberg GR, Reichart D, Olefsky JM, Henry RR. PMID: 3170749; PMCID: PMC442697.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansCells
    343. Insulin receptors with defective tyrosine kinase inhibit normal receptor function at the level of substrate phosphorylation. J Biol Chem. 1988 Sep 05; 263(25):12629-37. Maegawa H, Olefsky JM, Thies S, Boyd D, Ullrich A, McClain DA. PMID: 2970462.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    344. Restriction-fragment-length polymorphism in insulin-receptor gene and insulin resistance in NIDDM. Diabetes. 1988 Aug; 37(8):1071-5. McClain DA, Henry RR, Ullrich A, Olefsky JM. PMID: 2899037.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    345. Properties of a human insulin receptor with a COOH-terminal truncation. I. Insulin binding, autophosphorylation, and endocytosis. J Biol Chem. 1988 Jun 25; 263(18):8904-11. McClain DA, Maegawa H, Levy J, Huecksteadt T, Dull TJ, Lee J, Ullrich A, Olefsky JM. PMID: 2837467.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    346. Properties of a human insulin receptor with a COOH-terminal truncation. II. Truncated receptors have normal kinase activity but are defective in signaling metabolic effects. J Biol Chem. 1988 Jun 25; 263(18):8912-7. Maegawa H, McClain DA, Freidenberg G, Olefsky JM, Napier M, Lipari T, Dull TJ, Lee J, Ullrich A. PMID: 2837468.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    347. Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells. Diabetes. 1988 Jun; 37(6):806-15. McClain DA, Olefsky JM. PMID: 2838354.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    348. Intracellular insulin-receptor dissociation and segregation in a rat fibroblast cell line transfected with a human insulin receptor gene. J Biol Chem. 1988 May 05; 263(13):6101-8. Levy JR, Olefsky JM. PMID: 3283119.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    349. Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus. J Clin Invest. 1988 May; 81(5):1528-36. Garvey WT, Huecksteadt TP, Matthaei S, Olefsky JM. PMID: 3366906; PMCID: PMC442586.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansCells
    350. Endocytotic uptake, processing, and retroendocytosis of human biosynthetic proinsulin by rat fibroblasts transfected with the human insulin receptor gene. J Clin Invest. 1988 May; 81(5):1370-7. Levy JR, Ullrich A, Olefsky JM. PMID: 3284910; PMCID: PMC442566.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    351. Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion. Diabetes. 1988 May; 37(5):590-9. Garvey WT, Olefsky JM, Rubenstein AH, Kolterman OG. PMID: 3282946.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    352. Cycloheximide decreases glucose transporters in rat adipocyte plasma membranes without affecting insulin-stimulated glucose transport. Biochem J. 1988 Apr 15; 251(2):491-7. Matthaei S, Olefsky JM, Karnieli E. PMID: 3041964; PMCID: PMC1149029.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    353. Biochemical characterization and subcellular distribution of the glucose transporter from rat brain microvessels. Biochim Biophys Acta. 1987 Dec 11; 905(2):417-25. Matthaei S, Olefsky JM, Horuk R. PMID: 3318930.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    354. The trafficking and processing of insulin and insulin receptors in cultured rat hepatocytes. Endocrinology. 1987 Dec; 121(6):2075-86. Levy JR, Olefsky JM. PMID: 3315635.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    355. A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis. J Biol Chem. 1987 Oct 25; 262(30):14663-71. McClain DA, Maegawa H, Lee J, Dull TJ, Ulrich A, Olefsky JM. PMID: 3312193.
      View in: PubMed   Mentions: 81     Fields:    Translation:HumansCells
    356. Insulin receptor kinase following internalization in isolated rat adipocytes. J Biol Chem. 1987 Aug 05; 262(22):10557-64. Klein HH, Freidenberg GR, Matthaei S, Olefsky JM. PMID: 3038888.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    357. Adenosine modulates insulin activation of insulin receptor kinase in intact rat adipocytes. Endocrinology. 1987 Jun; 120(6):2339-45. Klein HH, Ciaraldi TP, Freidenberg GR, Olefsky JM. PMID: 3552635.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    358. Direct and indirect effects of insulin to inhibit hepatic glucose output in obese subjects. Diabetes. 1987 May; 36(5):607-11. Prager R, Wallace P, Olefsky JM. PMID: 3552793.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    359. Non-insulin-mediated glucose uptake predominates in postabsorptive dogs. Am J Physiol. 1987 May; 252(5 Pt 1):E660-6. Lavelle-Jones M, Scott MH, Kolterman O, Moossa AR, Olefsky JM. PMID: 2883896.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    360. In vivo regulation of non-insulin-mediated and insulin-mediated glucose uptake by epinephrine. J Clin Endocrinol Metab. 1987 May; 64(5):889-95. Baron AD, Wallace P, Olefsky JM. PMID: 2881942.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    361. Nuclear translocation of the insulin receptor. A possible mediator of insulin's long term effects. J Biol Chem. 1987 Mar 05; 262(7):3362-8. Podlecki DA, Smith RM, Kao M, Tsai P, Huecksteadt T, Brandenburg D, Lasher RS, Jarett L, Olefsky JM. PMID: 3546306.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    362. Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp. J Clin Invest. 1987 Mar; 79(3):790-800. Bergman RN, Prager R, Volund A, Olefsky JM. PMID: 3546379; PMCID: PMC424201.
      View in: PubMed   Mentions: 149     Fields:    Translation:Humans
    363. Human adipocyte glucose transport system. Biochemical and functional heterogeneity of hexose carriers. J Clin Invest. 1987 Mar; 79(3):703-9. Matthaei S, Garvey WT, Horuk R, Hueckstaedt TP, Olefsky JM. PMID: 3102556; PMCID: PMC424180.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    364. Hyperinsulinemia does not compensate for peripheral insulin resistance in obesity. Diabetes. 1987 Mar; 36(3):327-34. Prager R, Wallace P, Olefsky JM. PMID: 3542654.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    365. The effects of biosynthetic human proinsulin on carbohydrate metabolism in non-insulin-dependent diabetes mellitus. N Engl J Med. 1987 Feb 19; 316(8):443-9. Glauber HS, Henry RR, Wallace P, Frank BH, Galloway JA, Cohen RM, Olefsky JM. PMID: 3543679.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    366. The effect of insulin concentration on retroendocytosis in isolated rat adipocytes. Endocrinology. 1987 Feb; 120(2):450-6. Levy J, Olefsky JM. PMID: 3542501.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    367. Photolabeling of the adipocyte hexose carrier with an aryl azide derivative of maltose. Mol Cell Endocrinol. 1987 Feb; 49(2-3):181-8. May JM, Horuk R, Olefsky JM. PMID: 3556753.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    368. Selective suppression of hepatic glucose output by human proinsulin in the dog. Am J Physiol. 1987 Feb; 252(2 Pt 1):E230-6. Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. PMID: 2881485.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    369. Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance. J Biol Chem. 1987 Jan 05; 262(1):189-97. Garvey WT, Olefsky JM, Matthaei S, Marshall S. PMID: 3539929.
      View in: PubMed   Mentions: 45     Fields:    Translation:AnimalsCells
    370. Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects. J Clin Invest. 1987 Jan; 79(1):240-50. Freidenberg GR, Henry RR, Klein HH, Reichart DR, Olefsky JM. PMID: 3540010; PMCID: PMC424032.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansCells
    371. Adipocyte glycogen synthase and pyruvate dehydrogenase in obese and type II diabetic subjects. Am J Physiol. 1986 Oct; 251(4 Pt 1):E489-96. Mandarino LJ, Madar Z, Kolterman OG, Bell JM, Olefsky JM. PMID: 3094377.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    372. Demonstration of insulin receptors and modulation of alkaline phosphatase activity by insulin in rat osteoblastic cells. Endocrinology. 1986 Oct; 119(4):1786-92. Levy JR, Murray E, Manolagas S, Olefsky JM. PMID: 3530724.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    373. Blood-brain glucose transfer in diabetes mellitus. Decreased number of glucose transporters at blood-brain barrier. Diabetes. 1986 Oct; 35(10):1181-4. Matthaei S, Horuk R, Olefsky JM. PMID: 3530847.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    374. Effects of weight loss on mechanisms of hyperglycemia in obese non-insulin-dependent diabetes mellitus. Diabetes. 1986 Sep; 35(9):990-8. Henry RR, Wallace P, Olefsky JM. PMID: 3527829.
      View in: PubMed   Mentions: 62     Fields:    Translation:HumansAnimals
    375. Retroendocytosis of insulin in rat adipocytes. Endocrinology. 1986 Aug; 119(2):572-9. Levy JR, Olefsky JM. PMID: 3525121.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    376. Effect of the alpha-glucosidase inhibitor Bay-O-1248 on the metabolic response of nondiabetic and diabetic rats to a high-carbohydrate diet. Am J Clin Nutr. 1986 Aug; 44(2):206-11. Madar Z, Olefsky J. PMID: 3728357.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    377. In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects. J Clin Invest. 1986 Aug; 78(2):472-81. Prager R, Wallace P, Olefsky JM. PMID: 3525609; PMCID: PMC423584.
      View in: PubMed   Mentions: 42     Fields:    Translation:Humans
    378. Recycling of photoaffinity-labeled insulin receptors in rat adipocytes. Dissociation of insulin-receptor complexes is not required for receptor recycling. J Biol Chem. 1986 Jul 05; 261(19):8655-9. Huecksteadt T, Olefsky JM, Brandenberg D, Heidenreich KA. PMID: 3522577.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    379. Antiinsulin receptor antibodies in an insulin-dependent diabetic may arise as autoantiidiotypes. J Clin Endocrinol Metab. 1986 Jul; 63(1):56-61. Shoelson SE, Marshall S, Horikoshi H, Kolterman OG, Rubenstein AH, Olefsky JM. PMID: 3486878.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    380. Effects of aging on glucose-mediated glucose disposal and glucose transport. J Clin Invest. 1986 Jun; 77(6):2034-41. Fink RI, Wallace P, Olefsky JM. PMID: 3519685; PMCID: PMC370565.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    381. Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes. An in vitro system to measure histone kinase activity of insulin receptors activated in vivo. J Biol Chem. 1986 Apr 05; 261(10):4691-7. Klein HH, Freidenberg GR, Kladde M, Olefsky JM. PMID: 3007472.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    382. The effects of proinsulin pretreatment on the combined actions of insulin and proinsulin in normal man. J Clin Endocrinol Metab. 1986 Apr; 62(4):785-8. Glauber HS, Wallace P, Galloway J, Frank BH, Olefsky JM. PMID: 3512594.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    383. Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes. Nature. 1986 Apr 3-9; 320(6061):459-61. Maller JL, Pike LJ, Freidenberg GR, Cordera R, Stith BJ, Olefsky JM, Krebs EG. PMID: 3083266.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    384. Insulin induces progressive insulin resistance in cultured rat adipocytes. Sequential effects at receptor and multiple postreceptor sites. Diabetes. 1986 Mar; 35(3):258-67. Garvey WT, Olefsky JM, Marshall S. PMID: 3512337.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    385. Kinetics of biosynthetic human proinsulin action in isolated rat adipocytes. Diabetes. 1986 Mar; 35(3):318-23. Ciaraldi TP, Brady D, Olefsky JM. PMID: 3512342.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    386. Biochemical and functional heterogeneity of rat adipocyte glucose transporters. J Biol Chem. 1986 Feb 05; 261(4):1823-8. Horuk R, Matthaei S, Olefsky JM, Baly DL, Cushman SW, Simpson IA. PMID: 3511051.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    387. Insulin internalization and degradation in adipocytes from normal and type II diabetic subjects. J Clin Endocrinol Metab. 1986 Feb; 62(2):268-74. Jochen AL, Berhanu P, Olefsky JM. PMID: 3510222.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    388. Metabolic consequences of very-low-calorie diet therapy in obese non-insulin-dependent diabetic and nondiabetic subjects. Diabetes. 1986 Feb; 35(2):155-64. Henry RR, Wiest-Kent TA, Scheaffer L, Kolterman OG, Olefsky JM. PMID: 3510922.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    389. Regulation of epidermal growth factor receptor number and phosphorylation by fasting in rat liver. J Biol Chem. 1986 Jan 15; 261(2):752-7. Freidenberg GR, Klein HH, Kladde MP, Cordera R, Olefsky JM. PMID: 3001081.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    390. Glycemic effects of intensive caloric restriction and isocaloric refeeding in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab. 1985 Nov; 61(5):917-25. Henry RR, Scheaffer L, Olefsky JM. PMID: 4044780.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    391. Rates of noninsulin-mediated glucose uptake are elevated in type II diabetic subjects. J Clin Invest. 1985 Nov; 76(5):1782-8. Baron AD, Kolterman OG, Bell J, Mandarino LJ, Olefsky JM. PMID: 2865274; PMCID: PMC424207.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    392. Insulin receptor kinase activity in rat liver. Regulation by fasting and high carbohydrate feeding. J Biol Chem. 1985 Oct 15; 260(23):12444-53. Freidenberg GR, Klein HH, Cordera R, Olefsky JM. PMID: 2995376.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    393. Clinical, cellular, and physiologic effects of glyburide in non-insulin-dependent diabetes mellitus. Am J Med. 1985 Sep 20; 79(3B):109-12. Olefsky JM. PMID: 3931458.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    394. Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes. Am J Med. 1985 Sep 20; 79(3B):12-22. Olefsky JM, Ciaraldi TP, Kolterman OG. PMID: 3901744.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    395. Post-binding events in insulin action. Mol Cell Endocrinol. 1985 Aug; 42(1):1-20. Horuk R, Olefsky JM. PMID: 3896892.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    396. Insulin receptor down-regulation is linked to an insulin-induced postreceptor defect in the glucose transport system in rat adipocytes. J Clin Invest. 1985 Jul; 76(1):22-30. Garvey WT, Olefsky JM, Marshall S. PMID: 3894420; PMCID: PMC423695.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    397. The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus. Diabetes. 1985 Mar; 34(3):222-34. Garvey WT, Olefsky JM, Griffin J, Hamman RF, Kolterman OG. PMID: 3882489.
      View in: PubMed   Mentions: 126     Fields:    Translation:Humans
    398. The metabolic clearance of insulin and the feedback inhibition of insulin secretion are altered with aging. Diabetes. 1985 Mar; 34(3):275-80. Fink RI, Revers RR, Kolterman OG, Olefsky JM. PMID: 3882495.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimals
    399. Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus. J Clin Endocrinol Metab. 1985 Mar; 60(3):559-68. Garvey WT, Revers RR, Kolterman OG, Rubenstein AH, Olefsky JM. PMID: 3882736.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    400. Substrate specificities of insulin and epidermal growth factor receptor kinases. Biochem Biophys Res Commun. 1985 Feb 28; 127(1):254-63. Klein HH, Freidenberg GR, Cordera R, Olefsky JM. PMID: 2983709.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    401. The preparation and characterization of mono-iodinated photoreactive analogs of insulin. Biochem Biophys Res Commun. 1985 Feb 15; 126(3):1138-45. Heidenreich KA, Yip CC, Frank BH, Olefsky JM. PMID: 3884003.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    402. Dissociation of insulin resistance and decreased insulin receptor binding in Duchenne muscular dystrophy. J Clin Endocrinol Metab. 1985 Feb; 60(2):320-7. Freidenberg GR, Olefsky JM. PMID: 3965491.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    403. Insulin resistance in non-insulin dependent (type II) and insulin dependent (type I) diabetes mellitus. Adv Exp Med Biol. 1985; 189:176-205. Olefsky JM, Revers RR, Prince M, Henry RR, Garvey WT, Scarlett JA, Kolterman OG. PMID: 3898763.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    404. Post binding events in insulin action. Diabetes Metab Rev. 1985; 1(1-2):59-97. Horuk R, Olefsky JM. PMID: 3915252.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    405. Biosynthetic human insulin and proinsulin have additive but not synergistic effects on total body glucose disposal. J Clin Endocrinol Metab. 1984 Jun; 58(6):1094-8. Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Rubenstein A, Frank B, Galloway J, Olefsky JM. PMID: 6373809.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    406. The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. J Clin Endocrinol Metab. 1984 Jun; 58(6):973-9. Bergenstal RM, Cohen RM, Lever E, Polonsky K, Jaspan J, Blix PM, Revers R, Olefsky JM, Kolterman O, Steiner K, et al. PMID: 6373814.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    407. Metabolism of photoaffinity-labeled insulin receptors by adipocytes. Role of internalization, degradation, and recycling. J Biol Chem. 1984 May 25; 259(10):6511-5. Heidenreich KA, Brandenburg D, Berhanu P, Olefsky JM. PMID: 6373760.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    408. The impact of sulfonylurea treatment upon the mechanisms responsible for the insulin resistance in type II diabetes. Diabetes Care. 1984 May-Jun; 7 Suppl 1:81-8. Kolterman OG, Olefsky JM. PMID: 6376033.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    409. The physiological significance of the glucose intolerance of aging. J Gerontol. 1984 May; 39(3):273-8. Fink RI, Kolterman OG, Olefsky JM. PMID: 6371116.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    410. The acute and chronic effects of sulfonylurea therapy in type II diabetic subjects. Diabetes. 1984 Apr; 33(4):346-54. Kolterman OG, Gray RS, Shapiro G, Scarlett JA, Griffin J, Olefsky JM. PMID: 6423429.
      View in: PubMed   Mentions: 31     Fields:    Translation:Humans
    411. The role of the glucose transport system in the postreceptor defect in insulin action associated with human aging. J Clin Endocrinol Metab. 1984 Apr; 58(4):721-5. Fink RI, Kolterman OG, Kao M, Olefsky JM. PMID: 6699133.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    412. Influence of hyperglycemia on insulin's in vivo effects in type II diabetes. J Clin Invest. 1984 Mar; 73(3):664-72. Revers RR, Fink R, Griffin J, Olefsky JM, Kolterman OG. PMID: 6368585; PMCID: PMC425067.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    413. Lack of in vivo insulin resistance in controlled insulin-dependent, type I, diabetic patients. J Clin Endocrinol Metab. 1984 Feb; 58(2):353-8. Revers RR, Kolterman OG, Scarlett JA, Gray RS, Olefsky JM. PMID: 6363437.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    414. In vitro characterization of biosynthetic human proinsulin. Diabetes. 1984 Feb; 33(2):111-8. Podlecki DA, Frank BH, Olefsky JM. PMID: 6363165.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    415. Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing. J Clin Invest. 1983 Dec; 72(6):1958-70. Berhanu P, Kolterman OG, Baron A, Tsai P, Olefsky JM, Brandenburg D. PMID: 6358259; PMCID: PMC437036.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    416. Characteristics of binding of a low affinity, noncooperative insulin [( LeuB25]insulin) to IM-9 lymphocytes. Endocrinology. 1983 Dec; 113(6):1963-71. Green A, Frank BH, Rubenstein A, Tager H, Olefsky JM. PMID: 6357764.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    417. Length of acute exposure to insulin regulates the rate of deactivation of stimulated glucose transport in isolated rat adipocytes. Endocrinology. 1983 Nov; 113(5):1739-45. Ciaraldi TP, Olefsky JM. PMID: 6354696.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    418. Separate intracellular pathways for insulin receptor recycling and insulin degradation in isolated rat adipocytes. J Cell Physiol. 1983 Nov; 117(2):195-203. Marshall S, Olefsky JM. PMID: 6355127.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    419. Degradation of insulin receptors in rat adipocytes. Diabetes. 1983 Nov; 32(11):1001-9. Heidenreich KA, Berhanu P, Brandenburg D, Olefsky JM. PMID: 6357900.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    420. Effect of temperature on coupling of insulin receptors to stimulation of glucose transport in isolated rat adipocytes. Metabolism. 1983 Oct; 32(10):1002-8. Ciaraldi TP, Olefsky JM. PMID: 6350807.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    421. Characterization of the receptor binding properties of monoiodoinsulin isomers and the identification of different insulin receptor specificities in hepatic and extrahepatic tissues. Diabetes. 1983 Aug; 32(8):697-704. Podlecki DA, Frank BH, Kao M, Horikoshi H, Freidenberg G, Marshall S, Ciaraldi T, Olefsky JM. PMID: 6347766.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    422. Structural differences between insulin receptors in the brain and peripheral target tissues. J Biol Chem. 1983 Jul 25; 258(14):8527-30. Heidenreich KA, Zahniser NR, Berhanu P, Brandenburg D, Olefsky JM. PMID: 6345543.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    423. Food fallacies and blood sugar. N Engl J Med. 1983 Jul 07; 309(1):44-5. Crapo PA, Olefsky JM. PMID: 6855853.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    424. Low pH accelerates dissociation of receptor-bound insulin. Endocrinology. 1983 Jul; 113(1):37-42. Marshall S, Podlecki DA, Olefsky JM. PMID: 6345144.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    425. Insulin binding to erythrocytes incubated in vitro at physiological temperature. J Clin Endocrinol Metab. 1983 Jul; 57(1):107-14. Freidenberg GF, Kao M, Olefsky JM. PMID: 6343415.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    426. Relationship between serum glucose level and the metabolic clearance rate of glucose in non-insulin-dependent diabetes mellitus. Diabetes. 1983 Jul; 32(7):627-32. Revers RR, Kolterman OG, Olefsky JM. PMID: 6345242.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    427. Parallel decreases in the expression of receptors for insulin and insulin-like growth factor I in a mutant human fibroblast line. Diabetes. 1983 Jun; 32(6):541-4. Massague J, Freidenberg GF, Olefsky JM, Czech MP. PMID: 6313454.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    428. Mechanisms of insulin resistance in aging. J Clin Invest. 1983 Jun; 71(6):1523-35. Fink RI, Kolterman OG, Griffin J, Olefsky JM. PMID: 6345584; PMCID: PMC370358.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansCells
    429. Insulin treatment reverses the postreceptor defect in adipocyte 3-O-methylglucose transport in type II diabetes mellitus. J Clin Endocrinol Metab. 1983 Jun; 56(6):1195-201. Scarlett JA, Kolterman OG, Ciaraldi TP, Kao M, Olefsky JM. PMID: 6341390.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    430. Insulin resistance in noninsulin-dependent diabetes mellitus: impact of sulfonylurea agents in vivo and in vitro. Am J Med. 1983 Jan 17; 74(1A):82-101. Kolterman OG, Prince MJ, Olefsky JM. PMID: 6401923.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    431. Endocrine-metabolic relationships in patients with leprechaunism. J Natl Med Assoc. 1982 Dec; 74(12):1195-210. Elders MJ, Schedewie HK, Olefsky J, Givens B, Char F, Bier DM, Baldwin D, Fiser RH, Seyedabadi S, Rubenstein A. PMID: 7154104; PMCID: PMC2561419.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    432. Insulin resistance in humans. Gastroenterology. 1982 Dec; 83(6):1313-8. Olefsky JM. PMID: 6751927.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    433. Insulin-stimulated glucose transport in cultured fibroblasts from normal and noninsulin-dependent (type II) diabetic human subjects. J Clin Endocrinol Metab. 1982 Dec; 55(6):1226-30. Berhanu P, Tsai P, Olefsky JM. PMID: 6752171.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    434. Role of glucose transport in the postreceptor defect of non-insulin-dependent diabetes mellitus. Diabetes. 1982 Nov; 31(11):1016-22. Ciaraldi TP, Kolterman OG, Scarlett JA, Kao M, Olefsky JM. PMID: 6757010.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    435. In vivo deactivation of peripheral, hepatic, and pancreatic insulin action in man. Diabetes. 1982 Oct; 31(10):929-36. Gray RS, Scarlett JA, Griffin J, Olefsky JM, Kolterman OG. PMID: 6759226.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    436. The effects of oral fructose, sucrose, and glucose in subjects with reactive hypoglycemia. Diabetes Care. 1982 Sep-Oct; 5(5):512-7. Crapo PA, Scarlett JA, Kolterman OG, Sanders LR, Hofeldt FD, Olefsky JM. PMID: 6765227.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    437. Mechanisms of insulin degradation by isolated rat adipocytes. Mol Cell Biochem. 1982 Aug 20; 47(1):23-9. Olefsky JM, Saekow M. PMID: 6752691.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    438. Surface binding and rates of internalization of 125I-insulin in adipocytes and IM-9 lymphocytes. J Biol Chem. 1982 Aug 10; 257(15):8667-73. Olefsky JM, Kao M. PMID: 7047524.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    439. Internalization and degradation of a low affinity insulin ([LeuB24]insulin) by rat adipocytes. FEBS Lett. 1982 Aug 02; 144(2):255-8. Green A, Tager H, Rubenstein A, Frank B, Olefsky JM. PMID: 6749549.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    440. Kinetic relationships between insulin receptor binding and effects on glucose transport in isolated rat adipocytes. Biochemistry. 1982 Jul 06; 21(14):3475-80. Ciaraldi TP, Olefsky JM. PMID: 7052124.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    441. Internalization and intracellular processing of insulin and insulin receptors in adipocytes. Metabolism. 1982 Jul; 31(7):670-90. Olefsky JM, Marshall S, Berhanu P, Saekow M, Heidenreich K, Green A. PMID: 7045573.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimals
    442. Insulin treatment reverses the insulin resistance of type II diabetes mellitus. Diabetes Care. 1982 Jul-Aug; 5(4):353-63. Scarlett JA, Gray RS, Griffin J, Olefsky JM, Kolterman OG. PMID: 6759075.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    443. Insulin resistance in non-insulin-dependent, type II diabetes mellitus. Clin Endocrinol Metab. 1982 Jul; 11(2):363-88. Kolterman OG, Scarlett JA, Olefsky JM. PMID: 6754161.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    444. Internalization and molecular processing of insulin receptors in isolated rat adipocytes. Proc Natl Acad Sci U S A. 1982 Jul; 79(13):4069-73. Berhanu P, Olefsky JM, Tsai P, Thamm P, Saunders D, Brandenburg D. PMID: 7051001; PMCID: PMC346578.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    445. Insulin resistance and diabetes due to a genetic defect in insulin receptors. J Clin Endocrinol Metab. 1982 Jul; 55(1):123-31. Scarlett JA, Kolterman OG, Moore P, Saekow M, Insel J, Griffin J, Mako M, Rubenstein AH, Olefsky JM. PMID: 7042734.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    446. Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus. Am J Physiol. 1982 Jul; 243(1):E15-30. Olefsky JM, Kolterman OG, Scarlett JA. PMID: 7046470.
      View in: PubMed   Mentions: 49     Fields:    Translation:Humans
    447. Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation. Diabetes. 1982 May; 31(5 Pt 1):410-7. Berhanu P, Olefsky JM. PMID: 7152133.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    448. Comparison of the effects of insulin and H2O2 on adipocyte glucose transport. J Cell Physiol. 1982 Mar; 110(3):323-8. Ciaraldi TP, Olefsky JM. PMID: 7045141.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    449. Potentiation of insulin binding and insulin action by purified porcine relaxin. Ann N Y Acad Sci. 1982; 380:200-16. Olefsky JM, Saekow M, Kroc RL. PMID: 7044233.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    450. Effect of a glucosidase inhibitor on the metabolic response of diabetic rats to a high carbohydrate diet, consisting of starch and sucrose, or glucose. Metabolism. 1982 Jan; 31(1):88-92. Gray RS, Olefsky JM. PMID: 7043164.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    451. Hepatic ultrastructure in leprechaunism. Hepatic ultrastructural evidence suggesting a syndrome with defective hepatic glucose release. Virchows Arch A Pathol Anat Histol. 1982; 397(2):121-30. Roth SI, Schedewie HK, Bier DM, Conaway HH, Olefsky J, Rubenstein A, Elders MJ. PMID: 7179734.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    452. Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes. Proc Natl Acad Sci U S A. 1982 Jan; 79(2):427-31. Green A, Olefsky JM. PMID: 7043460; PMCID: PMC345756.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    453. Evidence for recycling of insulin receptors in isolated rat adipocytes. J Biol Chem. 1981 Nov 25; 256(22):11464-70. Marshall S, Green A, Olefsky JM. PMID: 7028734.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    454. Regulation of insulin receptors in cultured human fibroblasts. Endocrinology. 1981 Nov; 109(5):1754-9. Prince MJ, Baldwin D, Tsai P, Olefsky JM. PMID: 7297502.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    455. Simultaneous inhibition of insulin and somatomedin-C binding to cultured IM-9 lymphocytes by naturally occurring antireceptor antibodies. Diabetes. 1981 Nov; 30(11):979-82. Rosenfeld RG, Baldwin D, Dollar LA, Hintz RL, Olefsky JM, Rubenstein A. PMID: 6271619.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    456. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. J Clin Invest. 1981 Oct; 68(4):957-69. Kolterman OG, Gray RS, Griffin J, Burstein P, Insel J, Scarlett JA, Olefsky JM. PMID: 7287908; PMCID: PMC370882.
      View in: PubMed   Mentions: 148     Fields:    Translation:Humans
    457. Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity. J Clin Invest. 1981 Oct; 68(4):875-80. Ciaraldi TP, Kolterman OG, Olefsky JM. PMID: 7026616; PMCID: PMC370874.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    458. Tris (hydroxmethyl) aminomethane permits the expression of insulin-induced receptor loss in isolated rat adipocytes. Biochem Biophys Res Commun. 1981 Sep 30; 102(2):646-53. Marshall S, Olefsky JM. PMID: 7030343.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    459. Insulin binding, internalization, and receptor regulation in cultured human fibroblasts. Am J Physiol. 1981 Sep; 241(3):E251-60. Baldwin D, Prince M, Tsai P, Johnson C, Lotan R, Rubenstein AH, Olefsky JM. PMID: 7025657.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    460. Characterization of insulin-induced receptor loss and evidence for internalization of the insulin receptor. Diabetes. 1981 Sep; 30(9):746-53. Marshall S, Olefsky JM. PMID: 7021273.
      View in: PubMed   Mentions: 6     Fields:    Translation:Animals
    461. Cutaneous manifestations of leprechaunism. Arch Dermatol. 1981 Sep; 117(9):531-5. Roth SI, Schedewie HK, Herzberg VK, Olefsky J, Elders MJ, Rubenstein A. PMID: 7294844.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    462. Effects of prednisolone and dexamethasone in vivo and in vitro: studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes. Diabetologia. 1981 Aug; 21(2):149-53. De Pirro R, Green A, Kao MY, Olefsky JM. PMID: 7021286.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    463. Relationship between negative cooperativity and insulin action. Biochemistry. 1981 Jul 21; 20(15):4488-92. Olefsky JM, Green A, Ciaraldi TP, Saekow M, Rubenstein AH, Tager HS. PMID: 7025901.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    464. Insulin binding, internalization, and insulin receptor regulation in fibroblasts from type II, non-insulin-dependent diabetic subjects. Diabetes. 1981 Jul; 30(7):596-600. Prince MJ, Tsai P, Olefsky JM. PMID: 7018965.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    465. Effects of insulin and insulin-like agents on the glucose transport system of cultured human fibroblasts. Diabetes. 1981 Jun; 30(6):523-9. Berhanu P, Olefsky JM. PMID: 7014316.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    466. Metabolic requirements for deactivation of insulin-stimulated glucose transport in isolated rat adipocytes. Arch Biochem Biophys. 1981 May; 208(2):502-7. Ciaraldi TP, Olefsky JM. PMID: 7020602.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    467. Insulin binding in human pregnancy: comparisons to the postpartum, luteal, and follicular states. J Clin Endocrinol Metab. 1981 May; 52(5):937-41. Moore P, Kolterman O, Weyant J, Olefsky JM. PMID: 7014589.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    468. Hormonal and substrate responses to a standard meal in normal and hypertriglyceridemic subjects. Metabolism. 1981 Apr; 30(4):331-4. Crapo PA, Reaven GM, Olefsky JM. PMID: 7010076.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    469. Insulin binding, biologic activity, and metabolism of biosynthetic human insulin. Diabetes Care. 1981 Mar-Apr; 4(2):244-7. Olefsky JM. PMID: 7011736.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    470. LIlly lecture 1980. Insulin resistance and insulin action. An in vitro and in vivo perspective. Diabetes. 1981 Feb; 30(2):148-62. Olefsky JM. PMID: 7009267.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    471. Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes. Am J Med. 1981 Jan; 70(1):151-68. Olefsky JM, Kolterman OG. PMID: 7006388.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    472. The endocytotic-internalization pathway of insulin metabolism: relationship to insulin degradation and activation of glucose transport. Endocrinology. 1980 Dec; 107(6):1937-45. Marshall S, Olefsky JM. PMID: 7000505.
      View in: PubMed   Mentions: 8     Fields:    Translation:Animals
    473. Effect of a high carbohydrate diet on adipocyte glucose metabolism in spontaneously obese rats and insulin-deficient diabetic rats. Endocrinology. 1980 Dec; 107(6):2004-10. Saekow M, Olefsky JM. PMID: 7428703.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    474. Glucose kinetics in leprechaunism: accelerated fasting due to insulin resistance. J Clin Endocrinol Metab. 1980 Nov; 51(5):988-94. Bier DM, Schedewie H, Larner J, Olefsky J, Rubenstein A, Fiser RH, Craig JW, Elders MJ. PMID: 6999010.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    475. Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level. J Clin Invest. 1980 Oct; 66(4):763-72. Marshall S, Olefsky JM. PMID: 6999035; PMCID: PMC371651.
      View in: PubMed   Mentions: 38     Fields:    Translation:Animals
    476. Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway. Proc Natl Acad Sci U S A. 1980 Oct; 77(10):5975-8. Baldwin D, Prince M, Marshall S, Davies P, Olefsky JM. PMID: 6108561; PMCID: PMC350195.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    477. Direct in vitro effect of a sulfonylurea to increase human fibroblast insulin receptors. J Clin Invest. 1980 Sep; 66(3):608-11. Prince MJ, Olefsky JM. PMID: 6772676; PMCID: PMC371691.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    478. A defect in cell-mediated immune function in insulin-resistant diabetic and obese subjects. J Lab Clin Med. 1980 Sep; 96(3):535-43. Kolterman OG, Olefsky JM, Kurahara C, Taylor K. PMID: 6995542.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    479. Effects of oral fructose in normal, diabetic, and impaired glucose tolerance subjects. Diabetes Care. 1980 Sep-Oct; 3(5):575-82. Crapo PA, Kolterman OG, Olefsky JM. PMID: 7002511.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    480. Postprandial hormonal responses to different types of complex carbohydrate in individuals with impaired glucose tolerance. Am J Clin Nutr. 1980 Aug; 33(8):1723-8. Crapo PA, Kolterman OG, Waldeck N, Reaven GM, Olefsky JM. PMID: 6996472.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCTClinical Trials
    481. Characterization of a mutant human insulin species. J Biol Chem. 1980 Jul 10; 255(13):6098-105. Olefsky JM, Saekow M, Tager H, Rubenstein AH. PMID: 6993466.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    482. Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin. Proc Natl Acad Sci U S A. 1980 Jun; 77(6):3181-5. Tager H, Thomas N, Assoian R, Rubenstein A, Saekow M, Olefsky J, Kaiser ET. PMID: 6997872; PMCID: PMC349578.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    483. Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects. J Clin Invest. 1980 Jun; 65(6):1272-84. Kolterman OG, Insel J, Saekow M, Olefsky JM. PMID: 6997333; PMCID: PMC371464.
      View in: PubMed   Mentions: 124     Fields:    Translation:Humans
    484. Mechanism of hypertriglyceridaemia in diabetic patients with fasting hyperglycaemia. Diabetologia. 1980 Jun; 18(6):441-6. Greenfield M, Kolterman O, Olefsky J, Reaven GM. PMID: 7418956.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    485. Role of intracellular energy in insulin's ability to activate 3-O-methylglucose transport by rat adipocytes. Biochemistry. 1980 May 13; 19(10):2183-90. Siegel J, Olefsky JM. PMID: 6990973.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    486. Fructose, xylitol, and sorbitol. Diabetes Care. 1980 Mar-Apr; 3(2):390-3. Olefsky JM, Crapo P. PMID: 7389552.
      View in: PubMed   Mentions: 1     Fields:    
    487. Short-term regulation of insulin receptor affinity in man. Diabetes. 1980 Feb; 29(2):132-9. Insel JR, Kolterman OG, Saekow M, Olefsky JM. PMID: 6986298.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    488. Relationship between deactivation of insulin-stimulated glucose transport and insulin dissociation in isolated rat adipocytes. J Biol Chem. 1980 Jan 25; 255(2):327-30. Ciaraldi TP, Olefsky JM. PMID: 7356614.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    489. Diabetes due to secretion of an abnormal insulin. N Engl J Med. 1980 Jan 17; 302(3):129-35. Given BD, Mako ME, Tager HS, Baldwin D, Markese J, Rubenstein AH, Olefsky J, Kobayashi M, Kolterman O, Poucher R. PMID: 7350438.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    490. Pancreas. Clin Endocrinol Metab. 1979 Nov; 8(3):579-601. Olefsky JM, Kolterman OG. PMID: 389492.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    491. Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation. J Biol Chem. 1979 Oct 25; 254(20):10153-60. Marshall S, Olefsky JM. PMID: 489589.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    492. A structurally abnormal insulin causing human diabetes. Nature. 1979 Sep 13; 281(5727):122-5. Tager H, Given B, Baldwin D, Mako M, Markese J, Rubenstein A, Olefsky J, Kobayashi M, Kolterman O, Poucher R. PMID: 381941.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    493. Effect of a high carbohydrate diet on insulin binding to adipocytes and on insulin action in vivo in man. Diabetes. 1979 Aug; 28(8):731-6. Kolterman OG, Greenfield M, Reaven GM, Saekow M, Olefsky JM. PMID: 446930.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    494. Effect of experimental hyperinsulinaemia on intracellular glucose metabolism of isolated adipocytes. Diabetologia. 1979 Aug; 17(2):111-6. Kobayashi M, Olefsky JM. PMID: 488566.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    495. Insulin-stimulated glucose transport in human adipocytes. Am J Physiol. 1979 Jun; 236(6):E621-5. Ciaraldi TP, Kolterman OG, Siegel JA, Olefsky JM. PMID: 443417.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    496. The effects of acute and chronic starvation on insulin binding to isolated human adipocytes. J Clin Endocrinol Metab. 1979 May; 48(5):836-42. Kolterman OG, Saekow M, Olefsky JM. PMID: 429529.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    497. Interactions between insulin and its receptors after the initial binding event. Functional heterogeneity and relationships to insulin degradation. Diabetes. 1979 May; 28(5):460-71. Olefsky JM, Kobayashi M, Chang H. PMID: 437375.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    498. Comparison of the effects of insulin and insulin-like agents on different aspects of adipocyte metabolism. Horm Metab Res. 1979 Mar; 11(3):209-13. Olefsky JM. PMID: 447201.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    499. Coupling of insulin receptors to glucose transport: a temperature-dependent time lag in activation of glucose transport. Arch Biochem Biophys. 1979 Mar; 193(1):221-31. Ciaraldi TP, Olefsky JM. PMID: 453850.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    500. Relationship between in vivo insulin resistance and decreased insulin receptors in obese man. J Clin Endocrinol Metab. 1979 Mar; 48(3):487-94. Kolterman OG, Reaven GM, Olefsky JM. PMID: 429500.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    501. Further evidence for functional heterogeneity of adipocyte insulin receptors. Endocrinology. 1979 Feb; 104(2):462-6. Olefsky JM, Chang H. PMID: 446370.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    502. Effects of streptozotocin-induced diabetes on insulin binding, glucose transport, and intracellular glucose metabolism in isolated rat adipocytes. Diabetes. 1979 Feb; 28(2):87-95. Kobayashi M, Olefsky JM. PMID: 154427.
      View in: PubMed   Mentions: 44     Fields:    Translation:Animals
    503. Defect in glucose removal in nonketotic diabetic patients with fasting hyperglycemia. Diabetes. 1979 Jan; 28(1):32-4. Davis BM, Bernstein R, Kolterman O, Olefsky JM, Reaven GM. PMID: 569610.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    504. The effects of dietary carbohydrate content on insulin binding and glucose metabolism by isolated rat adipocytes. Endocrinology. 1978 Dec; 103(6):2252-63. Olefsky JM, Saekow M. PMID: 748046.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    505. Ability of circulating insulin to chronically regulate the cellular glucose transport system. Metabolism. 1978 Dec; 27(12 Suppl 2):1917-29. Olefsky JM, Kobayashi M. PMID: 723641.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    506. The effect of ten days of fasting on various aspects of carbohydrate metabolism in obese diabetic subjects with significant fasting hyperglycemia. Metabolism. 1978 Dec; 27(12 Suppl 2):1839-52. Greenfield M, Kolterman O, Olefsky JM, Reaven GM. PMID: 723636.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    507. Insulin binding to adipocytes. Evidence for functionally distinct receptors. Diabetes. 1978 Sep; 27(9):946-58. Olefsky JM, Chang H. PMID: 689306.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    508. Effect of experimental hyperinsulinemia on insulin binding and glucose transport in isolated rat adipocytes. Am J Physiol. 1978 Jul; 235(1):E53-62. Kobayashi M, Olefsky JM. PMID: 677310.
      View in: PubMed   Mentions: 31     Fields:    Translation:Animals
    509. Long-term regulation of adipocyte glucose transport capacity by circulating insulin in rats. J Clin Invest. 1978 Jul; 62(1):73-81. Kobayashi M, Olefsky JM. PMID: 659640; PMCID: PMC371738.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    510. Insulin resistance due to a defect distal to the insulin receptor: demonstration in a patient with leprechaunism. Proc Natl Acad Sci U S A. 1978 Jul; 75(7):3469-73. Kobayashi M, Olefsky JM, Elders J, Mako ME, Given BD, Schedwie HK, Fiser RH, Hintz RL, Horner JA, Rubenstein AH. PMID: 277948; PMCID: PMC392799.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    511. Mechanisms of the ability of insulin to activate the glucose-transport system in rat adipocytes. Biochem J. 1978 Apr 15; 172(1):137-45. Olefsky JM. PMID: 656068; PMCID: PMC1185672.
      View in: PubMed   Mentions: 44     Fields:    Translation:AnimalsCells
    512. Hepatic insulin responsiveness in patients with endogenous hypertriglyceridaemia. Diabetologia. 1978 Apr; 14(4):249-53. Bernstein RM, Davis BM, Olefsky JM, Reaven GM. PMID: 205476.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    513. Mechanisms of fasting-induced increase in insulin binding to rat adipocytes. J Clin Invest. 1978 Feb; 61(2):329-38. Olefsky JM, Kobayashi M. PMID: 621276; PMCID: PMC372543.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    514. The role of insulin resistance in the pathogenesis of diabetes mellitus. Adv Metab Disord. 1978; 9:313-31. Reaven GM, Olefsky JM. PMID: 417568.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    515. Postprandial plasma-glucose and -insulin responses to different complex carbohydrates. Diabetes. 1977 Dec; 26(12):1178-83. Crapo PA, Reaven G, Olefsky J. PMID: 590639.
      View in: PubMed   Mentions: 29     Fields:    Translation:Humans
    516. Factitious hypoglycemia. Diagnosis by measurement of serum C-peptide immunoreactivity and insulin-binding antibodies. N Engl J Med. 1977 Nov 10; 297(19):1029-32. Scarlett JA, Mako ME, Rubenstein AH, Blix PM, Goldman J, Horwitz DL, Tager H, Jaspan JB, Stjernholm MR, Olefsky JM. PMID: 198659.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    517. Does glucagon play a role in the insulin resistance of patients with adult non-ketotic diabetes? Diabetologia. 1977 Aug; 13(4):327-30. Olefsky JM, Sperling MA, Reaven GM. PMID: 913924.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    518. Insensitivity of large rat adipocytes to the antilipolytic effects of insulin. J Lipid Res. 1977 Jul; 18(4):459-64. Olefsky JM. PMID: 894138.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    519. Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity. Diabetes. 1977 Jul; 26(7):680-8. Olefsky JM, Reaven GM. PMID: 873075.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    520. Relationship between heterogeneity of insulin responses and insulin resistance in normal subjects and patients with chemical diabetes. Diabetologia. 1977 May; 13(3):201-6. Reaven GM, Olefsky JM. PMID: 873087.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    521. Mechanisms of decreased insulin responsiveness of large adipocytes. Endocrinology. 1977 Apr; 100(4):1169-77. Olefsky JM. PMID: 837879.
      View in: PubMed   Mentions: 19     Fields:    Translation:AnimalsCells
    522. Interaction between insulin receptors and glucose transport: effect of prostaglandin E2. Biochem Biophys Res Commun. 1977 Mar 21; 75(2):271-6. Olefsky JM. PMID: 851438.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    523. Effects of fasting on insulin binding, glucose transport, and glucose oxidation in isolated rat adipocytes: relationships between insulin receptors and insulin action. J Clin Invest. 1976 Dec; 58(6):1450-60. Olefsky JM. PMID: 993354; PMCID: PMC333317.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    524. The insulin receptor: its role in insulin resistance of obesity and diabetes. Diabetes. 1976 Dec; 25(12):1154-62. Olefsky JM. PMID: 791735.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    525. Plasma glucose and insulin responses to orally administered simple and complex carbohydrates. Diabetes. 1976 Sep; 25(9):741-7. Crapo PA, Reaven G, Olefsky J. PMID: 955301.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimals
    526. Locating the site(s) of insulin resistance in patients with nonketotic diabetes mellitus. Diabetes. 1976 Aug; 25(8):673-8. Kimmerling G, Javorski C, Olefsky JM, Reaven GM. PMID: 955298.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    527. Insulin's effect on glucose oxidation independent of glucose transport. Biochem Biophys Res Commun. 1976 Jul 12; 71(1):106-13. Olefsky JM. PMID: 962906.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    528. Insulin binding to monocytes and total mononuclear leukocytes from normal and diabetic patients. J Clin Endocrinol Metab. 1976 Jul; 43(1):226-31. Olefsky JM, Reaven GM. PMID: 947940.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    529. Postprandial plasma triglyceride and cholesterol responses to a low-fat meal. Am J Clin Nutr. 1976 May; 29(5):535-9. Olefsky JM, Crapo P, Reaven GM. PMID: 178167.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    530. Decreased insulin binding to adipocytes and circulating monocytes from obese subjects. J Clin Invest. 1976 May; 57(5):1165-72. Olefsky JM. PMID: 177453; PMCID: PMC436769.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    531. Induction of hypertriglyceridemia by a low-fat diet. J Clin Endocrinol Metab. 1976 Apr; 42(4):729-35. Ginsberg H, Olefsky JM, Kimmerling G, Crapo P, Reaven GM. PMID: 1262445.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    532. The effects of spontaneous obesity on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest. 1976 Apr; 57(4):842-51. Olefsky JM. PMID: 181402; PMCID: PMC436727.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    533. Effects of glucocorticoids on carbohydrate metabolism. Am J Med Sci. 1976 Mar-Apr; 271(2):202-10. Olefsky JM, Kimmerling G. PMID: 178180.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimals
    534. Nonketotic diabetes mellitus: insulin deficiency or insulin resistance? Am J Med. 1976 Jan; 60(1):80-8. Reaven GM, Bernstein R, Davis B, Olefsky JM. PMID: 814810.
      View in: PubMed   Mentions: 62     Fields:    Translation:Humans
    535. Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients. Am J Med. 1976 Jan; 60(1):89-95. Olefsky JM, Reaven GM. PMID: 175653.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    536. Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes. J Clin Invest. 1975 Dec; 56(6):1499-1508. Olefsky JM. PMID: 1202081; PMCID: PMC333128.
      View in: PubMed   Mentions: 54     Fields:    Translation:Animals
    537. Comparison of 125-I-insulin binding and degradation to isolated rat hepatocytes and liver membranes. Diabetes. 1975 Sep; 24(9):801-10. Olefsky J, Johnson J, Liu F, Edwards P, Baur S. PMID: 169175.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    538. Effects of age and obesity on insulin binding to isolated adipocytes. Endocrinology. 1975 Jun; 96(6):1486-98. Olefsky JM, Reaven GM. PMID: 165063.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    539. Quantification of plasma cholesterol and triglyceride levels in hypercholesterolemic subjects receiving ascorbic acid supplements. Am J Clin Nutr. 1975 Jun; 28(6):584-7. Peterson VE, Crapo PA, Weininger J, Ginsberg H, Olefsky J. PMID: 165703.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    540. Metabolic effects of increased caloric intake in man. Metabolism. 1975 Apr; 24(4):495-503. Olefsky J, Crapo PA, Ginsberg H, Reaven GM. PMID: 1117841.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    541. The effects of acute and chronic dexamethasone administration on insulin binding to isolated rat hepatocytes and adipocytes. Metabolism. 1975 Apr; 24(4):517-27. Olefsky JM, Johnson J, Liu F, Jen P, Reaven GM. PMID: 1117842.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    542. Evaluation of insulin resistance in patients with primary hyperparathyroidism. Proc Soc Exp Biol Med. 1975 Mar; 148(3):942-5. Ginsberg H, Olefsky JM, Reaven GM. PMID: 1129318.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    543. Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia. J Clin Invest. 1975 Mar; 55(3):454-61. Ginsberg H, Kimmerling G, Olefsky JM, Reaven GM. PMID: 1117064; PMCID: PMC301772.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    544. Removal of insulin by perfused rat liver: effect of concentration. Metabolism. 1975 Feb; 24(2):153-60. Mondon CE, Olefsky JM, Dolkas CB, Reaven GM. PMID: 1113679.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    545. Insulin sensitivity of isolated perfused rat liver. Diabetes. 1975 Feb; 24(2):225-9. Mondon CE, Dolkas CB, Olefsky JM, Reaven GM. PMID: 1123110.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    546. Decreased insulin binding to lymphocytes from diabetic subjects. J Clin Invest. 1974 Dec; 54(6):1323-8. Olefsky JM, Reaven GM. PMID: 4474186; PMCID: PMC301686.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    547. Reappraisal of the role of insulin in hypertriglyceridemia. Am J Med. 1974 Oct; 57(4):551-60. Olefsky JM, Farquhar JW, Reaven GM. PMID: 4372881.
      View in: PubMed   Mentions: 68     Fields:    Translation:Humans
    548. Further evidence that insulin resistance exists in patients with chemical diabetes. Diabetes. 1974 Aug; 23(8):674-8. Ginsberg H, Olefsky JM, Reaven GM. PMID: 4852112.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    549. Insulin binding to isolated human adipocytes. Diabetes. 1974 Jul; 23(7):565-71. Olefsky JM, Jen P, Reaven GM, Alto P. PMID: 4366488.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    550. Effect of intravenous glucose infusion on plasma insulin removal rate. Metabolism. 1974 Jun; 23(6):543-8. Olefsky JM, Batchelder T, Colome S, Reaven GM. PMID: 4828443.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    551. Insulin and glucose responses to identical oral glucose tolerance tests performed forty-eight hours apart. Diabetes. 1974 May; 23(5):449-53. Olefsky JM, Reaven GM. PMID: 4830180.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    552. Relationship between insulin response during the intravenous glucose tolerance test, rate of fractional glucose removal and the degree of insulin resistance in normal adults. Diabetes. 1974 May; 23(5):454-9. Reaven GM, Olefsky JM. PMID: 4830181.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    553. The human lymphocyte: a model for the study of insulin-receptor interaction. J Clin Endocrinol Metab. 1974 Apr; 38(4):554-60. Olefsky J, Reaven GM. PMID: 4362393.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimalsCells
    554. Sex difference in the kinetics of triglyceride metabolism in normal and hypertriglyceridaemic human subjects. Eur J Clin Invest. 1974 Apr; 4(2):121-27. Olefsky J, Farquhar JW, Reaven GM. PMID: 4365003.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    555. Moderate ethanol ingestion and plasma triglyceride levels. A study in normal and hypertriglyceridemic persons. Ann Intern Med. 1974 Feb; 80(2):143-9. Ginsberg H, Olefsky J, Farquhar JW, Reaven GM. PMID: 4359737.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    556. Effects of weight reduction on obesity. Studies of lipid and carbohydrate metabolism in normal and hyperlipoproteinemic subjects. J Clin Invest. 1974 Jan; 53(1):64-76. Olefsky J, Reaven GM, Farquhar JW. PMID: 4357617; PMCID: PMC301439.
      View in: PubMed   Mentions: 71     Fields:    Translation:Humans
    557. Increased plasma glucose and insulin responses to high-carbohydrate feedings in normal subjects. J Clin Endocrinol Metab. 1974 Jan; 38(1):151-4. Reaven GM, Olefsky JM. PMID: 4809638.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    558. Disassociation of the plasma insulin response from the blood glucose concentration during glucose infusions in normal dogs. Metabolism. 1973 Oct; 22(10):1277-86. Olefsky J, Batchelder T, Farquhar JW, Reaven GM. PMID: 4784528.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    559. Relationship between fasting plasma lipid levels and adipose tissue morphology. Metabolism. 1973 Oct; 22(10):1311-7. Stern MP, Olefsky J, Farquhar JW, Reaven GM. PMID: 4784530.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    560. Relationship between fasting plasma insulin level and resistance to insulin-mediated glucose uptake in normal and diabetic subjects. Diabetes. 1973 Jul; 22(7):507-13. Olefsky J, Farquhar JW, Reaven G. PMID: 4719190.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    561. Do the oral and intravenous glucose tolerance tests provide similar diagnostic information in patients with chemical diabetes mellitus? Diabetes. 1973 Mar; 22(3):202-9. Olefsky JM, Farquhar JW, Reaven GM. PMID: 4689294.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    562. Does hyperglycaemia or hyperinsulinaemia characterise the patient with chemical diabetes? Lancet. 1972 Jun 10; 1(7763):1247-9. Reaven GM, Olefsky J, Farquhar JW. PMID: 4113513.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    563. "Tertiary" hyperparathyroidism and apparent "cure" of vitamin-D-resistant rickets after removal of an ossifying mesenchymal tumor of the pharynx. N Engl J Med. 1972 Apr 06; 286(14):740-5. Olefsky J, Kempson R, Jones H, Reaven G. PMID: 4337228.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
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