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Mohit Jain

Title(s)Associate Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
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    School of MedicineM.D., Ph.D.Boston University

    Collapse Overview 

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    Collapse Research Activities and Funding
    Mapping the Plasma Exposome and its Association with Human Cardiovascular Disease
    NIH R01ES027595Feb 1, 2017 - Jan 31, 2022
    Role: Principal Investigator
    Mapping metabolic activities in stem cell-derived models of human cardiomyopathy
    NIH R03HL133720Aug 15, 2016 - Jul 31, 2018
    Role: Principal Investigator
    Reactive electrophiles in human aging and longevity
    NIH R03AG053287Aug 1, 2016 - Apr 30, 2018
    Role: Principal Investigator
    RapidFire mass spectrometry system
    NIH S10OD020025Apr 17, 2015 - Apr 16, 2016
    Role: Principal Investigator
    A systems approach to metabolic dysregulation in the heart
    NIH K08HL107451Apr 22, 2011 - Sep 1, 2013
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Biallelic variants in HPDL, encoding 4-hydroxyphenylpyruvate dioxygenase-like protein, lead to an infantile neurodegenerative condition. Genet Med. 2020 Nov 14. Ghosh SG, Lee S, Fabunan R, Chai G, Zaki MS, Abdel-Salam G, Sultan T, Ben-Omran T, Alvi JR, McEvoy-Venneri J, Stanley V, Patel A, Ross D, Ding J, Jain M, Pan D, Lübbert P, Kammerer B, Wiedemann N, Verhoeven-Duif NM, Jans JJ, Murphy D, Toosi MB, Ashrafzadeh F, Imannezhad S, Karimiani EG, Ibrahim K, Waters ER, Maroofian R, Gleeson JG. PMID: 33188300.
      View in: PubMed   Mentions:    Fields:    
    2. Metabolomic profiles associated with a mouse model of antipsychotic-induced food intake and weight gain. Sci Rep. 2020 10 29; 10(1):18581. Zapata RC, Rosenthal SB, Fisch K, Dao K, Jain M, Osborn O. PMID: 33122657.
      View in: PubMed   Mentions:    Fields:    
    3. Fructose stimulated de novo lipogenesis is promoted by inflammation. Nat Metab. 2020 10; 2(10):1034-1045. Todoric J, Di Caro G, Reibe S, Henstridge DC, Green CR, Vrbanac A, Ceteci F, Conche C, McNulty R, Shalapour S, Taniguchi K, Meikle PJ, Watrous JD, Moranchel R, Najhawan M, Jain M, Liu X, Kisseleva T, Diaz-Meco MT, Moscat J, Knight R, Greten FR, Lau LF, Metallo CM, Febbraio MA, Karin M. PMID: 32839596.
      View in: PubMed   Mentions:
    4. Effects of Diet versus Gastric Bypass on Metabolic Function in Diabetes. N Engl J Med. 2020 08 20; 383(8):721-732. Yoshino M, Kayser BD, Yoshino J, Stein RI, Reeds D, Eagon JC, Eckhouse SR, Watrous JD, Jain M, Knight R, Schechtman K, Patterson BW, Klein S. PMID: 32813948.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCTClinical Trials
    5. Imbalance Between Omega-6 and Omega-3 Derived Bioactive Lipids in Arthritis in the Elderly. J Gerontol A Biol Sci Med Sci. 2020 May 03. Coras R, Pedersen B, Narasimhan R, Brandy A, Mateo L, Prior A, Kavanaugh A, Armando AM, Jain M, Quehenberger O, Martinez M, Guma M. PMID: 32361743.
      View in: PubMed   Mentions:    Fields:    
    6. Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity. Mol Cell. 2020 02 20; 77(4):723-733.e6. Lau RK, Ye Q, Birkholz EA, Berg KR, Patel L, Mathews IT, Watrous JD, Ego K, Whiteley AT, Lowey B, Mekalanos JJ, Kranzusch PJ, Jain M, Pogliano J, Corbett KD. PMID: 31932164.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    7. HORMA Domain Proteins and a Trip13-like ATPase Regulate Bacterial cGAS-like Enzymes to Mediate Bacteriophage Immunity. Mol Cell. 2020 02 20; 77(4):709-722.e7. Ye Q, Lau RK, Mathews IT, Birkholz EA, Watrous JD, Azimi CS, Pogliano J, Jain M, Corbett KD. PMID: 31932165.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    8. Microbiota-Produced N-Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance. Diabetes. 2019 07; 68(7):1415-1426. Wollam J, Riopel M, Xu YJ, Johnson AMF, Ofrecio JM, Ying W, El Ouarrat D, Chan LS, Han AW, Mahmood NA, Ryan CN, Lee YS, Watrous JD, Chordia MD, Pan D, Jain M, Olefsky JM. PMID: 31010956.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. Pro- and anti-inflammatory eicosanoids in psoriatic arthritis. Metabolomics. 2019 04 19; 15(4):65. Coras R, Kavanaugh A, Boyd T, Huynh Q, Pedersen B, Armando AM, Dahlberg-Wright S, Marsal S, Jain M, Paravar T, Quehenberger O, Guma M. PMID: 31004236.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    10. Directed Non-targeted Mass Spectrometry and Chemical Networking for Discovery of Eicosanoids and Related Oxylipins. Cell Chem Biol. 2019 03 21; 26(3):433-442.e4. Watrous JD, Niiranen TJ, Lagerborg KA, Henglin M, Xu YJ, Rong J, Sharma S, Vasan RS, Larson MG, Armando A, Mora S, Quehenberger O, Dennis EA, Cheng S, Jain M. PMID: 30661990.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    11. Choline metabolite, trimethylamine N-oxide (TMAO), is associated with inflammation in psoriatic arthritis. Clin Exp Rheumatol. 2019 May-Jun; 37(3):481-484. Coras R, Kavanaugh A, Boyd T, Huynh D, Lagerborg KA, Xu YJ, Rosenthal SB, Jain M, Guma M. PMID: 30620278.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. High-Throughput Measure of Bioactive Lipids Using Non-targeted Mass Spectrometry. Methods Mol Biol. 2019; 1862:17-35. Lagerborg KA, Watrous JD, Cheng S, Jain M. PMID: 30315457.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    13. Restoring mitochondrial calcium uniporter expression in diabetic mouse heart improves mitochondrial calcium handling and cardiac function. J Biol Chem. 2018 05 25; 293(21):8182-8195. Suarez J, Cividini F, Scott BT, Lehmann K, Diaz-Juarez J, Diemer T, Dai A, Suarez JA, Jain M, Dillmann WH. PMID: 29626093.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    14. Krüppel-Like Factor 4 Regulation of Cholesterol-25-Hydroxylase and Liver X Receptor Mitigates Atherosclerosis Susceptibility. Circulation. 2017 Oct 03; 136(14):1315-1330. Li Z, Martin M, Zhang J, Huang HY, Bai L, Zhang J, Kang J, He M, Li J, Maurya MR, Gupta S, Zhou G, Sangwung P, Xu YJ, Lei T, Huang HD, Jain M, Jain MK, Subramaniam S, Shyy JY. PMID: 28794002.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansAnimals
    15. Visualization, Quantification, and Alignment of Spectral Drift in Population Scale Untargeted Metabolomics Data. Anal Chem. 2017 02 07; 89(3):1399-1404. PMID: 28208263.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    16. Viewing Extrinsic Proteotoxic Stress Through the Lens of Amyloid Cardiomyopathy. Physiology (Bethesda). 2016 07; 31(4):294-9. PMID: 27252164.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
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