Wai Cheung

Title(s)	Project Scientist, Pediatrics
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Single-Cell Analysis of Endothelial Cell Injury in IgA Nephropathy. Immun Inflamm Dis. 2025 Feb; 13(2):e70149. Yang YC, Zhu L, Zhao JY, Zhang B, Wang XM, Cheung WW, Zhao CG, Zhou P. PMID: 39945225; PMCID: PMC11822453.

View in: PubMed Mentions: Fields:
All Allergy and Immunology Com Communicable Diseases
Translation:Humans Cells
Risk factors and retreatment for relapse in childhood primary nephrotic syndrome treated with rituximab. Pediatr Nephrol. 2025 May; 40(5):1635-1644. Zhi Y, Cao L, Gu R, Wang Q, Shi P, Zhu L, Cheung WW, Zhou P, Zhang J. PMID: 39754695.

View in: PubMed Mentions: 1 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans Cells
Leptin signalling altered in infantile nephropathic cystinosis-related bone disorder. J Cachexia Sarcopenia Muscle. 2024 Dec; 15(6):2447-2459. Cheung WW, Zhou P, Zheng R, Gertler A, Oliveira EA, Mak RH. PMID: 39210624; PMCID: PMC11634524.

View in: PubMed Mentions: 1 Fields:
Neo Neoplasms Pat Pathology
Translation:Humans Animals Cells
Redox Signaling in Chronic Kidney Disease-Associated Cachexia. Antioxidants (Basel). 2023 Apr 18; 12(4). Simões E Silva AC, Oliveira EA, Cheung WW, Mak RH. PMID: 37107320; PMCID: PMC10136196.

View in: PubMed Mentions: 5
Growth Hormone Improves Adipose Tissue Browning and Muscle Wasting in Mice with Chronic Kidney Disease-Associated Cachexia. Int J Mol Sci. 2022 Dec 04; 23(23). Mak RH, Gunta S, Oliveira EA, Cheung WW. PMID: 36499637; PMCID: PMC9740214.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry Che Chemistry Mol Molecular Biology
Translation:Animals
Metabolic Advantage of 25(OH)D3 versus 1,25(OH)2D3 Supplementation in Infantile Nephropathic Cystinosis-Associated Adipose Tissue Browning and Muscle Wasting. Cells. 2022 10 17; 11(20). Zhou P, Cheung WW, Gonzalez A, Vaddi V, Oliveira EA, Mak RH. PMID: 36291130; PMCID: PMC9600749.

View in: PubMed Mentions: 3 Fields:
Bio Biophysics Cel Cell Biology Mol Molecular Biology
Translation:Animals
Differential Effects of 25-Hydroxyvitamin D3 versus 1α 25-Dihydroxyvitamin D3 on Adipose Tissue Browning in CKD-Associated Cachexia. Cells. 2021 12 01; 10(12). Mak RH, Querfeld U, Gonzalez A, Gunta S, Cheung WW. PMID: 34943890; PMCID: PMC8699879.

View in: PubMed Mentions: 4 Fields:
Bio Biophysics Cel Cell Biology Mol Molecular Biology
Translation:Animals Cells
A Leptin Receptor Antagonist Attenuates Adipose Tissue Browning and Muscle Wasting in Infantile Nephropathic Cystinosis-Associated Cachexia. Cells. 2021 07 31; 10(8). Gonzalez A, Cheung WW, Perens EA, Oliveira EA, Gertler A, Mak RH. PMID: 34440723; PMCID: PMC8393983.

View in: PubMed Mentions: 9 Fields:
Bio Biophysics Cel Cell Biology Mol Molecular Biology
Translation:Animals Cells
The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia. Sci Rep. 2021 07 23; 11(1):15141. Cheung WW, Zheng R, Hao S, Wang Z, Gonzalez A, Zhou P, Hoffman HM, Mak RH. PMID: 34302016; PMCID: PMC8302616.

View in: PubMed Mentions: 16 Fields:
Sci Science
Translation:Animals Cells
Targeting interleukin-1 for reversing fat browning and muscle wasting in infantile nephropathic cystinosis. J Cachexia Sarcopenia Muscle. 2021 10; 12(5):1296-1311. Cheung WW, Hao S, Zheng R, Wang Z, Gonzalez A, Zhou P, Hoffman HM, Mak RH. PMID: 34196133; PMCID: PMC8517356.

View in: PubMed Mentions: 9 Fields:
Neo Neoplasms Pat Pathology
Translation:Humans Animals
Vitamin D ameliorates adipose browning in chronic kidney disease cachexia. Sci Rep. 2020 08 25; 10(1):14175. Cheung WW, Ding W, Hoffman HM, Wang Z, Hao S, Zheng R, Gonzalez A, Zhan JY, Zhou P, Li S, Esparza MC, Lieber RL, Mak RH. PMID: 32843714; PMCID: PMC7447759.

View in: PubMed Mentions: 17 Fields:
Sci Science
Translation:Animals Cells
Vitamin D repletion ameliorates adipose tissue browning and muscle wasting in infantile nephropathic cystinosis-associated cachexia. J Cachexia Sarcopenia Muscle. 2020 02; 11(1):120-134. Cheung WW, Hao S, Wang Z, Ding W, Zheng R, Gonzalez A, Zhan JY, Zhou P, Li S, Esparza MC, Hoffman HM, Lieber RL, Mak RH. PMID: 31721480; PMCID: PMC7015252.

View in: PubMed Mentions: 21 Fields:
Neo Neoplasms Pat Pathology
Translation:Humans Animals
Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis. Kidney Int. 2019 08; 96(2):350-362. Lobry T, Miller R, Nevo N, Rocca CJ, Zhang J, Catz SD, Moore F, Thomas L, Pouly D, Bailleux A, Guerrera IC, Gubler MC, Cheung WW, Mak RH, Montier T, Antignac C, Cherqui S. PMID: 30928021; PMCID: PMC7269416.

View in: PubMed Mentions: 16 Fields:
Nep Nephrology
Translation:Humans Animals Cells
Preparation of Potent Leptin Receptor Antagonists and Their Therapeutic Use in Mouse Models of Uremic Cachexia and Kidney Fibrosis. Curr Pharm Des. 2018; 24(9):1012-1018. Mak RH, Cheung WW, Solomon G, Gertler A. PMID: 29366406.

View in: PubMed Mentions: 6 Fields:
Pha Pharmacology
Translation:Humans Animals
Emerging roles of nuclear phosphatase SCP4 in CKD-associated muscle wasting. Kidney Int. 2017 08; 92(2):281-283. Cheung WW, Hao S, Mak RH. PMID: 28709594.

View in: PubMed Mentions: 2 Fields:
Nep Nephrology
Translation:Humans Animals
MicroRNA as Novel Exercise Mimetic for Muscle Wasting in CKD. J Am Soc Nephrol. 2017 09; 28(9):2557-2559. Mak RH, Cheung WW. PMID: 28720683; PMCID: PMC5576951.

View in: PubMed Mentions: 3 Fields:
Nep Nephrology
Translation:Humans
Muscle wasting in chronic kidney disease. Pediatr Nephrol. 2018 05; 33(5):789-798. Oliveira EA, Cheung WW, Toma KG, Mak RH. PMID: 28508131.

View in: PubMed Mentions: 17 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans
Andrographolide ameliorates diabetic nephropathy by attenuating hyperglycemia-mediated renal oxidative stress and inflammation via Akt/NF-κB pathway. Mol Cell Endocrinol. 2016 12 05; 437:268-279. Ji X, Li C, Ou Y, Li N, Yuan K, Yang G, Chen X, Yang Z, Liu B, Cheung WW, Wang L, Huang R, Lan T. PMID: 27378149.

View in: PubMed Mentions: 38 Fields:
Cel Cell Biology End Endocrinology Mol Molecular Biology
Translation:Humans Animals Cells
Inflammation and nutrition in children with chronic kidney disease. World J Nephrol. 2016 May 06; 5(3):274-82. Tu J, Cheung WW, Mak RH. PMID: 27152263; PMCID: PMC4848150.

View in: PubMed Mentions: 9
Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis. J Cachexia Sarcopenia Muscle. 2016 05; 7(2):152-64. Cheung WW, Cherqui S, Ding W, Esparza M, Zhou P, Shao J, Lieber RL, Mak RH. PMID: 27493869; PMCID: PMC4864942.

View in: PubMed Mentions: 16 Fields:
Neo Neoplasms Pat Pathology
Impact of obesity on kidney function and blood pressure in children. World J Nephrol. 2015 May 06; 4(2):223-9. Ding W, Cheung WW, Mak RH. PMID: 25949935; PMCID: PMC4419131.

View in: PubMed Mentions: 13
Exploiting the therapeutic potential of leptin signaling in cachexia. Curr Opin Support Palliat Care. 2014 Dec; 8(4):352-7. Mak RH, Cheung WW, Gertler A. PMID: 25259544.

View in: PubMed Mentions: 4 Fields:
Pal Palliative Care The Therapeutics
Translation:Humans Animals Cells
C/EBPα regulates macrophage activation and systemic metabolism. Am J Physiol Endocrinol Metab. 2014 May 15; 306(10):E1144-54. Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. PMID: 24691027; PMCID: PMC4025063.

View in: PubMed Mentions: 31 Fields:
End Endocrinology Met Metabolism Phy Physiology
Translation:Animals Cells
A pegylated leptin antagonist ameliorates CKD-associated cachexia in mice. J Am Soc Nephrol. 2014 Jan; 25(1):119-28. Cheung WW, Ding W, Gunta SS, Gu Y, Tabakman R, Klapper LN, Gertler A, Mak RH. PMID: 24115476; PMCID: PMC3871780.

View in: PubMed Mentions: 16 Fields:
Nep Nephrology
Translation:Animals Cells
Melanocortin antagonism ameliorates muscle wasting and inflammation in chronic kidney disease. Am J Physiol Renal Physiol. 2012 Nov 01; 303(9):F1315-24. Cheung WW, Mak RH. PMID: 22914778; PMCID: PMC3518185.

View in: PubMed Mentions: 23 Fields:
Nep Nephrology Phy Physiology
Translation:Animals Cells
MicroRNAs: a new therapeutic frontier for muscle wasting in chronic kidney disease. Kidney Int. 2012 Aug; 82(4):373-4. Mak RH, Cheung WW. PMID: 22846810.

View in: PubMed Mentions: 7 Fields:
Nep Nephrology
Translation:Animals
Recent advances in obesity: genetics and beyond. ISRN Endocrinol. 2012; 2012:536905. Cheung WW, Mao P. PMID: 22474595; PMCID: PMC3313574.

View in: PubMed Mentions: 33
Is ghrelin a biomarker for mortality in end-stage renal disease? Kidney Int. 2011 Apr; 79(7):697-9. Mak RH, Cheung WW. PMID: 21403653.

View in: PubMed Mentions: 11 Fields:
Nep Nephrology
Translation:Humans
Endogenous epinephrine protects against obesity induced insulin resistance. Auton Neurosci. 2011 Jul 05; 162(1-2):32-4. Ziegler MG, Milic M, Sun P, Tang CM, Elayan H, Bao X, Cheung WW, O'Connor DT. PMID: 21354376; PMCID: PMC3111898.

View in: PubMed Mentions: 9 Fields:
Neu Neurology
Translation:Animals
Cachexia and protein-energy wasting in children with chronic kidney disease. Pediatr Nephrol. 2012 Feb; 27(2):173-81. Mak RH, Cheung WW, Zhan JY, Shen Q, Foster BJ. PMID: 21298504; PMCID: PMC3249542.

View in: PubMed Mentions: 40 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans
The impact of inflammation on bone mass in children. Pediatr Nephrol. 2011 Nov; 26(11):1937-46. Cheung WW, Zhan JY, Paik KH, Mak RH. PMID: 21197596; PMCID: PMC3178021.

View in: PubMed Mentions: 10 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans Cells
Ghrelin in chronic kidney disease. Int J Pept. 2010; 2010. Cheung WW, Mak RH. PMID: 20721357; PMCID: PMC2915808.

View in: PubMed Mentions: 13
Inflammation and cachexia in chronic kidney disease. Pediatr Nephrol. 2010 Apr; 25(4):711-24. Cheung WW, Paik KH, Mak RH. PMID: 20111974.

View in: PubMed Mentions: 69 Fields:
Nep Nephrology Ped Pediatrics
Translation:Humans
A novel pathway of insulin sensitivity in chromogranin A null mice: a crucial role for pancreastatin in glucose homeostasis. J Biol Chem. 2009 Oct 16; 284(42):28498-509. Gayen JR, Saberi M, Schenk S, Biswas N, Vaingankar SM, Cheung WW, Najjar SM, O'Connor DT, Bandyopadhyay G, Mahata SK. PMID: 19706599; PMCID: PMC2781393.

View in: PubMed Mentions: 45 Fields:
Bio Biochemistry
Translation:Animals Cells
Ghrelin and its analogues as therapeutic agents for anorexia and cachexia in end-stage renal disease. Kidney Int. 2009 Jul; 76(2):135-7. Cheung WW, Mak RH. PMID: 19564855.

View in: PubMed Mentions: 7 Fields:
Nep Nephrology
Translation:Humans
Modulation of melanocortin signaling ameliorates uremic cachexia. Kidney Int. 2008 Jul; 74(2):180-6. Cheung WW, Rosengren S, Boyle DL, Mak RH. PMID: 18432186.

View in: PubMed Mentions: 22 Fields:
Nep Nephrology
Translation:Humans Animals Cells
Therapeutic strategy for cachexia in chronic kidney disease. Curr Opin Nephrol Hypertens. 2007 Nov; 16(6):542-6. Mak RH, Cheung W. PMID: 18089968.

View in: PubMed Mentions: 7 Fields:
Nep Nephrology Vas Vascular Diseases
Translation:Humans
The growth hormone-insulin-like growth factor-I axis in chronic kidney disease. Growth Horm IGF Res. 2008 Feb; 18(1):17-25. Mak RH, Cheung WW, Roberts CT. PMID: 17826224; PMCID: PMC2706146.

View in: PubMed Mentions: 25 Fields:
End Endocrinology
Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice. J Am Soc Nephrol. 2007 Sep; 18(9):2517-24. Cheung WW, Kuo HJ, Markison S, Chen C, Foster AC, Marks DL, Mak RH. PMID: 17687077.

View in: PubMed Mentions: 27 Fields:
Nep Nephrology
Translation:Animals
Adipokines and gut hormones in end-stage renal disease. Perit Dial Int. 2007 Jun; 27 Suppl 2:S298-302. Mak RH, Cheung W. PMID: 17556323.

View in: PubMed Mentions: 11 Fields:
Nep Nephrology
Translation:Humans
Animal models of obesity-associated chronic kidney disease. Adv Chronic Kidney Dis. 2006 Oct; 13(4):374-85. Mak RH, Kuo HJ, Cheung WW. PMID: 17045223.

View in: PubMed Mentions: 1 Fields:
Nep Nephrology
Translation:Humans Animals