Wulf Palinski

Title(s)Recall Faculty, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Developmental immune programming and postnatal atherosclerosis
    NIH R01HL089559Apr 1, 2008 - May 31, 2013
    Role: Principal Investigator
    Fetal Determinants of Atherosclerosis
    NIH R01HL067792Feb 1, 2003 - Jan 31, 2008
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Combination of Genomic Landsscape and 3D Culture Functional Assays Bridges Sarcoma Phenotype to Target and Immunotherapy. Cells. 2023 09 04; 12(17). de Nigris F, Meo C, Palinski W. PMID: 37681936; PMCID: PMC10486752.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. Therapeutic targeting of P2X4 receptor and mitochondrial metabolism in clear cell renal carcinoma models. J Exp Clin Cancer Res. 2023 May 26; 42(1):134. Rupert C, Dell' Aversana C, Mosca L, Montanaro V, Arcaniolo D, De Sio M, Bilancio A, Altucci L, Palinski W, Pili R, de Nigris F. PMID: 37231503; PMCID: PMC10214673.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    3. Maternal hypercholesterolaemia during pregnancy affects severity of myocardial infarction in young adults. Eur J Prev Cardiol. 2022 05 05; 29(5):758-765. Cacciatore F, Bruzzese G, Abete P, Russo G, Palinski W, Napoli C. PMID: 34662903.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    4. Lysosome purinergic receptor P2X4 regulates neoangiogenesis induced by microvesicles from sarcoma patients. Cell Death Dis. 2021 08 17; 12(9):797. Palinski W, Monti M, Camerlingo R, Iacobucci I, Bocella S, Pinto F, Iannuzzi C, Mansueto G, Pignatiello S, Fazioli F, Gallo M, Marra L, Cozzolino F, De Chiara A, Pucci P, Bilancio A, de Nigris F. PMID: 34404763; PMCID: PMC8371002.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    5. A Gut Feeling About Developmental Programming Mechanisms: Trimethylamine-N-Oxide May Enhance Atherosclerosis in Offspring of Hypercholesterolemic Mice. Arterioscler Thromb Vasc Biol. 2017 11; 37(11):1979-1980. Palinski W. PMID: 29070534.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    6. Effect of maternal cardiovascular conditions and risk factors on offspring cardiovascular disease. Circulation. 2014 May 20; 129(20):2066-77. Palinski W. PMID: 24842934; PMCID: PMC4053195.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    7. A novel mathematical model detecting early individual changes of insulin resistance. Diabetes Technol Ther. 2013 Oct; 15(10):870-80. Eberle C, Palinski W, Ament C. PMID: 23919589; PMCID: PMC3781137.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Glycoxydation promotes vascular damage via MAPK-ERK/JNK pathways. J Cell Physiol. 2012 Nov; 227(11):3639-47. de Nigris F, Rienzo M, Sessa M, Infante T, Cesario E, Ignarro LJ, Al-Omran M, Giordano A, Palinski W, Napoli C. PMID: 22331607.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    9. Scavenger receptors target glycolipids for natural killer T cell activation. J Clin Invest. 2012 Nov; 122(11):3943-54. Freigang S, Landais E, Zadorozhny V, Kain L, Yoshida K, Liu Y, Deng S, Palinski W, Savage PB, Bendelac A, Teyton L. PMID: 23064364; PMCID: PMC3484437.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    10. Maternal immunization affects in utero programming of insulin resistance and type 2 diabetes. PLoS One. 2012; 7(9):e45361. Eberle C, Merki E, Yamashita T, Johnson S, Armando AM, Quehenberger O, Napoli C, Palinski W. PMID: 23028961; PMCID: PMC3445481.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    11. It takes three to tango: genes complicate the association between birth weight and cardiovascular disease. Circulation. 2011 Jun 21; 123(24):2773-5. Palinski W. PMID: 21690499.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    12. Effect of gestational hypercholesterolemia and maternal immunization on offspring plasma eicosanoids. Am J Obstet Gynecol. 2011 Aug; 205(2):156.e15-25. Quehenberger O, Yamashita T, Armando AM, Dennis EA, Palinski W. PMID: 21621186; PMCID: PMC3175501.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsPHPublic Health
    13. Influence of maternal dysmetabolic conditions during pregnancy on cardiovascular disease. J Cardiovasc Transl Res. 2009 Sep; 2(3):277-85. Palinski W, Nicolaides E, Liguori A, Napoli C. PMID: 19655024; PMCID: PMC2719748.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    14. Maternal-fetal cholesterol transport in the placenta: good, bad, and target for modulation. Circ Res. 2009 Mar 13; 104(5):569-71. Palinski W. PMID: 19286612.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    15. Sodium exposure induces stroke in a genetically susceptible model: new insights into early-life factors modulating adult disease. Circulation. 2009 Mar 24; 119(11):1459-62. Palinski W. PMID: 19273716.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    16. Maternal C-reactive protein and developmental programming of atherosclerosis. Am J Obstet Gynecol. 2008 Mar; 198(3):281.e1-5. Liguori A, D'Armiento FP, Palagiano A, Palinski W, Napoli C. PMID: 18313449.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    17. Impaired fetal growth, cardiovascular disease, and the need to move on. Circulation. 2008 Jan 22; 117(3):341-3. Palinski W, Napoli C. PMID: 18212299.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    18. Developmental programming: maternal hypercholesterolemia and immunity influence susceptibility to atherosclerosis. Nutr Rev. 2007 Dec; 65(12 Pt 2):S182-7. Palinski W, Yamashita T, Freigang S, Napoli C. PMID: 18240546.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    19. Effect of gestational hypercholesterolaemia on omental vasoreactivity, placental enzyme activity and transplacental passage of normal and oxidised fatty acids. BJOG. 2007 Dec; 114(12):1547-56. Liguori A, D'Armiento FP, Palagiano A, Balestrieri ML, Williams-Ignarro S, de Nigris F, Lerman LO, D'Amora M, Rienzo M, Fiorito C, Ignarro LJ, Palinski W, Napoli C. PMID: 17903226.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    20. A diet-induced hypercholesterolemic murine model to study atherogenesis without obesity and metabolic syndrome. Arterioscler Thromb Vasc Biol. 2007 Apr; 27(4):878-85. Hartvigsen K, Binder CJ, Hansen LF, Rafia A, Juliano J, Hörkkö S, Steinberg D, Palinski W, Witztum JL, Li AC. PMID: 17255537.
      View in: PubMed   Mentions: 42     Fields:    Translation:Animals
    21. Maternal immunization programs postnatal immune responses and reduces atherosclerosis in offspring. Circ Res. 2006 Sep 29; 99(7):e51-64. Yamashita T, Freigang S, Eberle C, Pattison J, Gupta S, Napoli C, Palinski W. PMID: 16946133.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    22. Minimally oxidized LDL offsets the apoptotic effects of extensively oxidized LDL and free cholesterol in macrophages. Arterioscler Thromb Vasc Biol. 2006 May; 26(5):1169-76. Boullier A, Li Y, Quehenberger O, Palinski W, Tabas I, Witztum JL, Miller YI. PMID: 16484596.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    23. Peroxisome proliferator-activated receptors: how their effects on macrophages can lead to the development of a new drug therapy against atherosclerosis. Annu Rev Pharmacol Toxicol. 2006; 46:1-39. Li AC, Palinski W. PMID: 16402897.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    24. Neurodegenerative diseases: insights into pathogenic mechanisms from atherosclerosis. Neurobiol Aging. 2005 Mar; 26(3):293-302. Napoli C, Palinski W. PMID: 15639306.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    25. Differential inhibition of macrophage foam-cell formation and atherosclerosis in mice by PPARalpha, beta/delta, and gamma. J Clin Invest. 2004 Dec; 114(11):1564-76. Li AC, Binder CJ, Gutierrez A, Brown KK, Plotkin CR, Pattison JW, Valledor AF, Davis RA, Willson TM, Witztum JL, Palinski W, Glass CK. PMID: 15578089; PMCID: PMC529277.
      View in: PubMed   Mentions: 202     Fields:    Translation:HumansAnimalsCells
    26. Reduced in vivo aortic uptake of radiolabeled oxidation-specific antibodies reflects changes in plaque composition consistent with plaque stabilization. Arterioscler Thromb Vasc Biol. 2004 Dec; 24(12):2307-12. Torzewski M, Shaw PX, Han KR, Shortal B, Lackner KJ, Witztum JL, Palinski W, Tsimikas S. PMID: 15528482.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    27. Aneurysms: leukotrienes weaken aorta from the outside. Nat Med. 2004 Sep; 10(9):896-8. Palinski W. PMID: 15340408.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    28. IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest. 2004 Aug; 114(3):427-37. Binder CJ, Hartvigsen K, Chang MK, Miller M, Broide D, Palinski W, Curtiss LK, Corr M, Witztum JL. PMID: 15286809; PMCID: PMC484976.
      View in: PubMed   Mentions: 169     Fields:    Translation:AnimalsCells
    29. United they go: conjunct regulation of aortic antioxidant enzymes during atherogenesis. Circ Res. 2003 Aug 08; 93(3):183-5. Palinski W. PMID: 12907662.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    30. Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL. Nat Med. 2003 Jun; 9(6):736-43. Binder CJ, Hörkkö S, Dewan A, Chang MK, Kieu EP, Goodyear CS, Shaw PX, Palinski W, Witztum JL, Silverman GJ. PMID: 12740573.
      View in: PubMed   Mentions: 279     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    31. Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):1420-5. de Nigris F, Lerman LO, Ignarro SW, Sica G, Lerman A, Palinski W, Ignarro LJ, Napoli C. PMID: 12525696; PMCID: PMC298788.
      View in: PubMed   Mentions: 33     Fields:    Translation:HumansAnimalsCells
    32. Immunomodulatory effects of statins: mechanisms and potential impact on arteriosclerosis. J Am Soc Nephrol. 2002 Jun; 13(6):1673-81. Palinski W, Tsimikas S. PMID: 12039998.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    33. Maternal hypercholesterolemia during pregnancy promotes early atherogenesis in LDL receptor-deficient mice and alters aortic gene expression determined by microarray. Circulation. 2002 Mar 19; 105(11):1360-7. Napoli C, de Nigris F, Welch JS, Calara FB, Stuart RO, Glass CK, Palinski W. PMID: 11901049.
      View in: PubMed   Mentions: 55     Fields:    Translation:Animals
    34. Scavenger receptors, oxidized LDL, and atherosclerosis. Ann N Y Acad Sci. 2001 Dec; 947:214-22; discussion 222-3. Boullier A, Bird DA, Chang MK, Dennis EA, Friedman P, Gillotre-Taylor K, Hörkkö S, Palinski W, Quehenberger O, Shaw P, Steinberg D, Terpstra V, Witztum JL. PMID: 11795269.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimals
    35. Maternal hypercholesterolemia and treatment during pregnancy influence the long-term progression of atherosclerosis in offspring of rabbits. Circ Res. 2001 Nov 23; 89(11):991-6. Palinski W, D'Armiento FP, Witztum JL, de Nigris F, Casanada F, Condorelli M, Silvestre M, Napoli C. PMID: 11717155.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    36. Troglitazone inhibits formation of early atherosclerotic lesions in diabetic and nondiabetic low density lipoprotein receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2001 Mar; 21(3):365-71. Collins AR, Meehan WP, Kintscher U, Jackson S, Wakino S, Noh G, Palinski W, Hsueh WA, Law RE. PMID: 11231915.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    37. Anticardiolipin antibodies from patients with the antiphospholipid antibody syndrome recognize epitopes in both beta(2)-glycoprotein 1 and oxidized low-density lipoprotein. Circulation. 2001 Feb 20; 103(7):941-6. Hörkkö S, Olee T, Mo L, Branch DW, Woods VL, Palinski W, Chen PP, Witztum JL. PMID: 11181467.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    38. Circulating autoantibodies to oxidized cardiolipin correlate with isoprostane F(2alpha)-VI levels and the extent of atherosclerosis in ApoE-deficient mice: modulation by vitamin E. Blood. 2001 Jan 15; 97(2):459-64. Praticò D, Tangirala RK, Hörkkö S, Witztum JL, Palinski W, FitzGerald GA. PMID: 11154223.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    39. Maternal hypercholesterolemia during pregnancy influences the later development of atherosclerosis: clinical and pathogenic implications. Eur Heart J. 2001 Jan; 22(1):4-9. Napoli C, Palinski W. PMID: 11133201.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimals
    40. Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol. 2001 Jan; 21(1):95-100. Tsimikas S, Palinski W, Witztum JL. PMID: 11145939.
      View in: PubMed   Mentions: 47     Fields:    Translation:AnimalsCells
    41. Immunomodulation: a new role for statins? Nat Med. 2000 Dec; 6(12):1311-2. Palinski W. PMID: 11100105.
      View in: PubMed   Mentions: 20     Fields:    Translation:Cells
    42. Maternal hypercholesterolemia enhances atherogenesis in normocholesterolemic rabbits, which is inhibited by antioxidant or lipid-lowering intervention during pregnancy: an experimental model of atherogenic mechanisms in human fetuses. Circ Res. 2000 Nov 10; 87(10):946-52. Napoli C, Witztum JL, Calara F, de Nigris F, Palinski W. PMID: 11073892.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    43. Evidence for oxidative activation of c-Myc-dependent nuclear signaling in human coronary smooth muscle cells and in early lesions of Watanabe heritable hyperlipidemic rabbits: protective effects of vitamin E. Circulation. 2000 Oct 24; 102(17):2111-7. de Nigris F, Youssef T, Ciafré S, Franconi F, Anania V, Condorelli G, Palinski W, Napoli C. PMID: 11044429.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    44. Mildly oxidized low density lipoprotein activates multiple apoptotic signaling pathways in human coronary cells. FASEB J. 2000 Oct; 14(13):1996-2007. Napoli C, Quehenberger O, De Nigris F, Abete P, Glass CK, Palinski W. PMID: 11023984.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    45. Determination of atherogenesis in apolipoprotein E-knockout mice. Nutr Metab Cardiovasc Dis. 2000 Aug; 10(4):209-15. Napoli C, Palinski W, Di Minno G, D'Armiento FP. PMID: 11079259.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    46. Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice. J Clin Invest. 2000 Aug; 106(4):523-31. Li AC, Brown KK, Silvestre MJ, Willson TM, Palinski W, Glass CK. PMID: 10953027; PMCID: PMC380255.
      View in: PubMed   Mentions: 211     Fields:    Translation:HumansAnimalsCells
    47. Polymerase chain reaction-based method for quantifying recruitment of monocytes to mouse atherosclerotic lesions in vivo: enhancement by tumor necrosis factor-alpha and interleukin-1 beta. Arterioscler Thromb Vasc Biol. 2000 Aug; 20(8):1976-82. Kim CJ, Khoo JC, Gillotte-Taylor K, Li A, Palinski W, Glass CK, Steinberg D. PMID: 10938020.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    48. Immunological responses to oxidized LDL. Free Radic Biol Med. 2000 Jun 15; 28(12):1771-9. Hörkkö S, Binder CJ, Shaw PX, Chang MK, Silverman G, Palinski W, Witztum JL. PMID: 10946219.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimals
    49. Natural antibodies with the T15 idiotype may act in atherosclerosis, apoptotic clearance, and protective immunity. J Clin Invest. 2000 Jun; 105(12):1731-40. Shaw PX, Hörkkö S, Chang MK, Curtiss LK, Palinski W, Silverman GJ, Witztum JL. PMID: 10862788; PMCID: PMC378505.
      View in: PubMed   Mentions: 261     Fields:    Translation:AnimalsCells
    50. Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis. J Intern Med. 2000 Mar; 247(3):371-80. Palinski W, Witztum JL. PMID: 10762454.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansAnimalsCells
    51. In vivo uptake of radiolabeled MDA2, an oxidation-specific monoclonal antibody, provides an accurate measure of atherosclerotic lesions rich in oxidized LDL and is highly sensitive to their regression. Arterioscler Thromb Vasc Biol. 2000 Mar; 20(3):689-97. Tsimikas S, Shortal BP, Witztum JL, Palinski W. PMID: 10712392.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    52. Neo-self antigens and the expansion of B-1 cells: lessons from atherosclerosis-prone mice. Curr Top Microbiol Immunol. 2000; 252:189-200. Silverman GJ, Shaw PX, Luo L, Dwyer D, Chang M, Horkko S, Palinski W, Stall A, Witztum JL. PMID: 11125476.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    53. Inhibition of VCAM-1 expression in the arterial wall is shared by structurally different antioxidants that reduce early atherosclerosis in NZW rabbits. J Lipid Res. 1999 Nov; 40(11):1958-66. Fruebis J, Silvestre M, Shelton D, Napoli C, Palinski W. PMID: 10552999.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    54. Influence of maternal hypercholesterolaemia during pregnancy on progression of early atherosclerotic lesions in childhood: Fate of Early Lesions in Children (FELIC) study. Lancet. 1999 Oct 09; 354(9186):1234-41. Napoli C, Glass CK, Witztum JL, Deutsch R, D'Armiento FP, Palinski W. PMID: 10520631.
      View in: PubMed   Mentions: 133     Fields:    Translation:Humans
    55. Pathophysiological events during pregnancy influence the development of atherosclerosis in humans. Trends Cardiovasc Med. 1999 Oct; 9(7):205-14. Palinski W, Napoli C. PMID: 10881753.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    56. 1,4-Dihydropyridine calcium channel blockers inhibit plasma and LDL oxidation and formation of oxidation-specific epitopes in the arterial wall and prolong survival in stroke-prone spontaneously hypertensive rats. Stroke. 1999 Sep; 30(9):1907-15. Napoli C, Salomone S, Godfraind T, Palinski W, Capuzzi DM, Palumbo G, D'Armiento FP, Donzelli R, de Nigris F, Capizzi RL, Mancini M, Gonnella JS, Bianchi A. PMID: 10471444.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    57. Western-type diets induce insulin resistance and hyperinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet. Arterioscler Thromb Vasc Biol. 1999 May; 19(5):1223-30. Merat S, Casanada F, Sutphin M, Palinski W, Reaven PD. PMID: 10323773.
      View in: PubMed   Mentions: 53     Fields:    Translation:Animals
    58. Intracranial arteries of human fetuses are more resistant to hypercholesterolemia-induced fatty streak formation than extracranial arteries. Circulation. 1999 Apr 20; 99(15):2003-10. Napoli C, Witztum JL, de Nigris F, Palumbo G, D'Armiento FP, Palinski W. PMID: 10209005.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansCells
    59. Angiogenesis inhibitors endostatin or TNP-470 reduce intimal neovascularization and plaque growth in apolipoprotein E-deficient mice. Circulation. 1999 Apr 06; 99(13):1726-32. Moulton KS, Heller E, Konerding MA, Flynn E, Palinski W, Folkman J. PMID: 10190883.
      View in: PubMed   Mentions: 153     Fields:    Translation:Animals
    60. Are immunological mechanisms relevant for the development of atherosclerosis? Clin Immunol. 1999 Feb; 90(2):153-6. Witztum JL, Palinski W. PMID: 10080825.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    61. Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. J Clin Invest. 1999 Jan; 103(1):117-28. Hörkkö S, Bird DA, Miller E, Itabe H, Leitinger N, Subbanagounder G, Berliner JA, Friedman P, Dennis EA, Curtiss LK, Palinski W, Witztum JL. PMID: 9884341; PMCID: PMC407862.
      View in: PubMed   Mentions: 177     Fields:    Translation:AnimalsCells
    62. Radiolabeled MDA2, an oxidation-specific, monoclonal antibody, identifies native atherosclerotic lesions in vivo. J Nucl Cardiol. 1999 Jan-Feb; 6(1 Pt 1):41-53. Tsimikas S, Palinski W, Halpern SE, Yeung DW, Curtiss LK, Witztum JL. PMID: 10070840.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    63. Immunization of LDL receptor-deficient mice with homologous malondialdehyde-modified and native LDL reduces progression of atherosclerosis by mechanisms other than induction of high titers of antibodies to oxidative neoepitopes. Arterioscler Thromb Vasc Biol. 1998 Dec; 18(12):1972-82. Freigang S, Hörkkö S, Miller E, Witztum JL, Palinski W. PMID: 9848892.
      View in: PubMed   Mentions: 79     Fields:    Translation:AnimalsCellsPHPublic Health
    64. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. Proc Natl Acad Sci U S A. 1998 Jun 23; 95(13):7614-9. Ricote M, Huang J, Fajas L, Li A, Welch J, Najib J, Witztum JL, Auwerx J, Palinski W, Glass CK. PMID: 9636198; PMCID: PMC22700.
      View in: PubMed   Mentions: 166     Fields:    Translation:HumansAnimalsCells
    65. An animal model to study local oxidation of LDL and its biological effects in the arterial wall. Arterioscler Thromb Vasc Biol. 1998 Jun; 18(6):884-93. Calara F, Dimayuga P, Niemann A, Thyberg J, Diczfalusy U, Witztum JL, Palinski W, Shah PK, Cercek B, Nilsson J, Regnström J. PMID: 9633927.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    66. Effect of probucol on LDL oxidation and atherosclerosis in LDL receptor-deficient mice. J Lipid Res. 1998 May; 39(5):1079-90. Bird DA, Tangirala RK, Fruebis J, Steinberg D, Witztum JL, Palinski W. PMID: 9610776.
      View in: PubMed   Mentions: 10     Fields:    Translation:Animals
    67. Abnormal iron deposition associated with lipid peroxidation in transgenic mice expressing interleukin-6 in the brain. J Neuropathol Exp Neurol. 1998 Mar; 57(3):268-82. Castelnau PA, Garrett RS, Palinski W, Witztum JL, Campbell IL, Powell HC. PMID: 9600219.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    68. Extent of antioxidant protection of plasma LDL is not a predictor of the antiatherogenic effect of antioxidants. J Lipid Res. 1997 Dec; 38(12):2455-64. Fruebis J, Bird DA, Pattison J, Palinski W. PMID: 9458269.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    69. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions. J Clin Invest. 1997 Dec 01; 100(11):2680-90. Napoli C, D'Armiento FP, Mancini FP, Postiglione A, Witztum JL, Palumbo G, Palinski W. PMID: 9389731; PMCID: PMC508471.
      View in: PubMed   Mentions: 209     Fields:    Translation:HumansCells
    70. Effect of streptozotocin-induced hyperglycemia on lipid profiles, formation of advanced glycation endproducts in lesions, and extent of atherosclerosis in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol. 1997 Oct; 17(10):2250-6. Reaven P, Merat S, Casanada F, Sutphin M, Palinski W. PMID: 9351397.
      View in: PubMed   Mentions: 34     Fields:    Translation:Animals
    71. The epitopes for some antiphospholipid antibodies are adducts of oxidized phospholipid and beta2 glycoprotein 1 (and other proteins). Proc Natl Acad Sci U S A. 1997 Sep 16; 94(19):10356-61. Hörkkö S, Miller E, Branch DW, Palinski W, Witztum JL. PMID: 9294215; PMCID: PMC23367.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    72. Effect of probucol treatment on gene expression of VCAM-1, MCP-1, and M-CSF in the aortic wall of LDL receptor-deficient rabbits during early atherogenesis. Arterioscler Thromb Vasc Biol. 1997 Jul; 17(7):1289-302. Fruebis J, Gonzalez V, Silvestre M, Palinski W. PMID: 9261259.
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    73. Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and evidence for their presence in vivo. J Biol Chem. 1997 May 23; 272(21):13597-607. Watson AD, Leitinger N, Navab M, Faull KF, Hörkkö S, Witztum JL, Palinski W, Schwenke D, Salomon RG, Sha W, Subbanagounder G, Fogelman AM, Berliner JA. PMID: 9153208.
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    74. A new approach to determining the rates of recruitment of circulating leukocytes into tissues: application to the measurement of leukocyte recruitment into atherosclerotic lesions. Proc Natl Acad Sci U S A. 1997 Apr 15; 94(8):4040-4. Steinberg D, Khoo JC, Glass CK, Palinski W, Almazan F. PMID: 9108101; PMCID: PMC20564.
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    75. Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein. J Clin Invest. 1996 Aug 01; 98(3):815-25. Hörkkö S, Miller E, Dudl E, Reaven P, Curtiss LK, Zvaifler NJ, Terkeltaub R, Pierangeli SS, Branch DW, Palinski W, Witztum JL. PMID: 8698874; PMCID: PMC507492.
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    76. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma. J Clin Invest. 1996 Aug 01; 98(3):800-14. Palinski W, Hörkkö S, Miller E, Steinbrecher UP, Powell HC, Curtiss LK, Witztum JL. PMID: 8698873; PMCID: PMC507491.
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    77. Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice. J Lipid Res. 1995 Nov; 36(11):2320-8. Tangirala RK, Rubin EM, Palinski W. PMID: 8656070.
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    78. Effect of vitamin E on atherogenesis in LDL receptor-deficient rabbits. Atherosclerosis. 1995 Oct; 117(2):217-24. Fruebis J, Carew TE, Palinski W. PMID: 8801867.
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    79. Increased autoantibody titers against epitopes of oxidized LDL in LDL receptor-deficient mice with increased atherosclerosis. Arterioscler Thromb Vasc Biol. 1995 Oct; 15(10):1569-76. Palinski W, Tangirala RK, Miller E, Young SG, Witztum JL. PMID: 7583529.
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    80. Effect of the antioxidant N,N'-diphenyl 1,4-phenylenediamine (DPPD) on atherosclerosis in apoE-deficient mice. Arterioscler Thromb Vasc Biol. 1995 Oct; 15(10):1625-30. Tangirala RK, Casanada F, Miller E, Witztum JL, Steinberg D, Palinski W. PMID: 7583536.
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    81. Atherogenesis in transgenic mice with human apolipoprotein B and lipoprotein (a). J Clin Invest. 1995 Sep; 96(3):1639-46. Callow MJ, Verstuyft J, Tangirala R, Palinski W, Rubin EM. PMID: 7657833; PMCID: PMC185790.
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    82. Scavenger receptor A gene regulatory elements target gene expression to macrophages and to foam cells of atherosclerotic lesions. Proc Natl Acad Sci U S A. 1995 Jun 06; 92(12):5391-5. Horvai A, Palinski W, Wu H, Moulton KS, Kalla K, Glass CK. PMID: 7777517; PMCID: PMC41700.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    83. Immunological evidence for the presence of advanced glycosylation end products in atherosclerotic lesions of euglycemic rabbits. Arterioscler Thromb Vasc Biol. 1995 May; 15(5):571-82. Palinski W, Koschinsky T, Butler SW, Miller E, Vlassara H, Cerami A, Witztum JL. PMID: 7749871.
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    84. Aminoguanidine has both pro-oxidant and antioxidant activity toward LDL. Arterioscler Thromb Vasc Biol. 1995 Mar; 15(3):367-76. Philis-Tsimikas A, Parthasarathy S, Picard S, Palinski W, Witztum JL. PMID: 7749847.
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    85. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis. Proc Natl Acad Sci U S A. 1995 Jan 31; 92(3):821-5. Palinski W, Miller E, Witztum JL. PMID: 7846059; PMCID: PMC42712.
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    86. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb. 1994 Apr; 14(4):605-16. Palinski W, Ord VA, Plump AS, Breslow JL, Steinberg D, Witztum JL. PMID: 7511933.
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    87. Pre-eclampsia and serum antibodies to oxidised low-density lipoprotein. Lancet. 1994 Mar 12; 343(8898):645-6. Branch DW, Mitchell MD, Miller E, Palinski W, Witztum JL. PMID: 7509433.
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    88. Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL. Arterioscler Thromb. 1994 Jan; 14(1):32-40. Ylä-Herttuala S, Palinski W, Butler SW, Picard S, Steinberg D, Witztum JL. PMID: 7506053.
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    89. Abundant expression of apoprotein E by macrophages in human and rabbit atherosclerotic lesions. Arterioscler Thromb. 1993 Sep; 13(9):1382-9. Rosenfeld ME, Butler S, Ord VA, Lipton BA, Dyer CA, Curtiss LK, Palinski W, Witztum JL. PMID: 8364022.
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    90. Autoantibody against oxidised LDL and progression of carotid atherosclerosis. Lancet. 1992 Apr 11; 339(8798):883-7. Salonen JT, Ylä-Herttuala S, Yamamoto R, Butler S, Korpela H, Salonen R, Nyyssönen K, Palinski W, Witztum JL. PMID: 1348295.
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    91. Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy. Am J Pathol. 1991 Jul; 139(1):81-100. Schröder S, Palinski W, Schmid-Schönbein GW. PMID: 1713023; PMCID: PMC1886150.
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    92. Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts. J Clin Invest. 1991 Jan; 87(1):90-9. Rosenfeld ME, Khoo JC, Miller E, Parthasarathy S, Palinski W, Witztum JL. PMID: 1985115; PMCID: PMC294999.
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    93. Lipoproteins in normal and atherosclerotic aorta. Eur Heart J. 1990 Aug; 11 Suppl E:88-99. Ylä-Herttuala S, Palinski W, Rosenfeld ME, Steinberg D, Witztum JL. PMID: 2226537.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    94. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoprotein. Arteriosclerosis. 1990 May-Jun; 10(3):325-35. Palinski W, Ylä-Herttuala S, Rosenfeld ME, Butler SW, Socher SA, Parthasarathy S, Curtiss LK, Witztum JL. PMID: 1693068.
      View in: PubMed   Mentions: 115     Fields:    Translation:AnimalsCells
    95. Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits. Arteriosclerosis. 1990 May-Jun; 10(3):336-49. Rosenfeld ME, Palinski W, Ylä-Herttuala S, Butler S, Witztum JL. PMID: 1693069.
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    96. Macrophages, endothelial cells, and lipoprotein oxidation in the pathogenesis of atherosclerosis. Toxicol Pathol. 1990; 18(4 Pt 1):560-71. Rosenfeld ME, Palinski W, Ylä-Herttuala S, Carew TE. PMID: 2091235.
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    97. Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J Clin Invest. 1989 Oct; 84(4):1086-95. Ylä-Herttuala S, Palinski W, Rosenfeld ME, Parthasarathy S, Carew TE, Butler S, Witztum JL, Steinberg D. PMID: 2794046; PMCID: PMC329764.
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    98. Low density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci U S A. 1989 Feb; 86(4):1372-6. Palinski W, Rosenfeld ME, Ylä-Herttuala S, Gurtner GC, Socher SS, Butler SW, Parthasarathy S, Carew TE, Steinberg D, Witztum JL. PMID: 2465552; PMCID: PMC286692.
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    99. Comparison of uptake and degradation of low density lipoproteins by arteries and veins of rabbits. Atherosclerosis. 1987 Jul; 66(1-2):131-8. Shafi S, Palinski W, Born GV. PMID: 3632745.
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