Beth Friedman

Title(s)Project Scientist, Computer Science and Engineering
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. CellBoost: A pipeline for machine assisted annotation in Neuroanatomy. bioRxiv. 2024 Jan 21. Qian K, Friedman B, Takatoh J, Wang F, Kleinfeld D, Freund Y. PMID: 38293051; PMCID: PMC10827062.
      View in: PubMed   Mentions:
    2. A lone spike in blood glucose can enhance the thrombo-inflammatory response in cortical venules. J Cereb Blood Flow Metab. 2024 02; 44(2):252-271. Shaked I, Foo C, Mächler P, Liu R, Cui Y, Ji X, Broggini T, Kaminski T, Suryakant Jadhav S, Sundd P, Firer M, Devor A, Friedman B, Kleinfeld D. PMID: 37737093.
      View in: PubMed   Mentions: 1     Fields:    
    3. Brain microvasculature has a common topology with local differences in geometry that match metabolic load. Neuron. 2021 04 07; 109(7):1168-1187.e13. Ji X, Ferreira T, Friedman B, Liu R, Liechty H, Bas E, Chandrashekar J, Kleinfeld D. PMID: 33657412; PMCID: PMC8525211.
      View in: PubMed   Mentions: 30     Fields:    Translation:Animals
    4. An active texture-based digital atlas enables automated mapping of structures and markers across brains. Nat Methods. 2019 04; 16(4):341-350. Chen Y, McElvain LE, Tolpygo AS, Ferrante D, Friedman B, Mitra PP, Karten HJ, Freund Y, Kleinfeld D. PMID: 30858600; PMCID: PMC6736610.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    5. Nerve-targeted probes for fluorescence-guided intraoperative imaging. Theranostics. 2018; 8(15):4226-4237. Hingorani DV, Whitney MA, Friedman B, Kwon JK, Crisp JL, Xiong Q, Gross L, Kane CJ, Tsien RY, Nguyen QT. PMID: 30128049; PMCID: PMC6096382.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    6. Detection of Subclinical Arthritis in Mice by a Thrombin Receptor-Derived Imaging Agent. Arthritis Rheumatol. 2018 01; 70(1):69-79. Friedman B, Whitney MA, Savariar EN, Caneda C, Steinbach P, Xiong Q, Hingorani DV, Crisp J, Adams SR, Kenner M, Lippert CN, Nguyen QT, Guma M, Tsien RY, Corr M. PMID: 29164814; PMCID: PMC5745304.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    7. Circuits in the rodent brainstem that control whisking in concert with other orofacial motor actions. Neuroscience. 2018 Jan 01; 368:152-170. McElvain LE, Friedman B, Karten HJ, Svoboda K, Wang F, Deschênes M, Kleinfeld D. PMID: 28843993; PMCID: PMC5849401.
      View in: PubMed   Mentions: 25     Fields:    Translation:Animals
    8. Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization. Proc Natl Acad Sci U S A. 2016 Nov 08; 113(45):12774-12779. Glasgow HL, Whitney MA, Gross LA, Friedman B, Adams SR, Crisp JL, Hussain T, Frei AP, Novy K, Wollscheid B, Nguyen QT, Tsien RY. PMID: 27791138; PMCID: PMC5111686.
      View in: PubMed   Mentions: 11     Fields:    
    9. Fluorescently labeled peptide increases identification of degenerated facial nerve branches during surgery and improves functional outcome. PLoS One. 2015; 10(3):e0119600. Hussain T, Mastrodimos MB, Raju SC, Glasgow HL, Whitney M, Friedman B, Moore JD, Kleinfeld D, Steinbach P, Messer K, Pu M, Tsien RY, Nguyen QT. PMID: 25751149; PMCID: PMC4353702.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    10. Fluorescent ligand for human progesterone receptor imaging in live cells. Bioconjug Chem. 2013 May 15; 24(5):766-71. Weinstain R, Kanter J, Friedman B, Ellies LG, Baker ME, Tsien RY. PMID: 23600997; PMCID: PMC3658552.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    11. In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):E726-35. Butko MT, Savas JN, Friedman B, Delahunty C, Ebner F, Yates JR, Tsien RY. PMID: 23382246; PMCID: PMC3581967.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    12. The smallest stroke: occlusion of one penetrating vessel leads to infarction and a cognitive deficit. Nat Neurosci. 2013 Jan; 16(1):55-63. Shih AY, Blinder P, Tsai PS, Friedman B, Stanley G, Lyden PD, Kleinfeld D. PMID: 23242312; PMCID: PMC3952571.
      View in: PubMed   Mentions: 158     Fields:    Translation:HumansAnimals
    13. Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation. Angew Chem Int Ed Engl. 2013 Jan 02; 52(1):325-30. Whitney M, Savariar EN, Friedman B, Levin RA, Crisp JL, Glasgow HL, Lefkowitz R, Adams SR, Steinbach P, Nashi N, Nguyen QT, Tsien RY. PMID: 23080482; PMCID: PMC3694763.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    14. In vivo fluorescence imaging of atherosclerotic plaques with activatable cell-penetrating peptides targeting thrombin activity. Integr Biol (Camb). 2012 Jun; 4(6):595-605. Olson ES, Whitney MA, Friedman B, Aguilera TA, Crisp JL, Baik FM, Jiang T, Baird SM, Tsimikas S, Tsien RY, Nguyen QT. PMID: 22534729; PMCID: PMC3689578.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    15. Improved facial nerve identification with novel fluorescently labeled probe. Laryngoscope. 2011 Apr; 121(4):805-10. Wu AP, Whitney MA, Crisp JL, Friedman B, Tsien RY, Nguyen QT. PMID: 21328585; PMCID: PMC3364140.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    16. Fluorescent peptides highlight peripheral nerves during surgery in mice. Nat Biotechnol. 2011 Apr; 29(4):352-6. Whitney MA, Crisp JL, Nguyen LT, Friedman B, Gross LA, Steinbach P, Tsien RY, Nguyen QT. PMID: 21297616; PMCID: PMC3364105.
      View in: PubMed   Mentions: 93     Fields:    Translation:HumansAnimalsCells
    17. Correlations of neuronal and microvascular densities in murine cortex revealed by direct counting and colocalization of nuclei and vessels. J Neurosci. 2009 Nov 18; 29(46):14553-70. Tsai PS, Kaufhold JP, Blinder P, Friedman B, Drew PJ, Karten HJ, Lyden PD, Kleinfeld D. PMID: 19923289; PMCID: PMC4972024.
      View in: PubMed   Mentions: 271     Fields:    Translation:AnimalsCells
    18. Severe blood-brain barrier disruption and surrounding tissue injury. Stroke. 2009 Dec; 40(12):e666-74. Chen B, Friedman B, Cheng Q, Tsai P, Schim E, Kleinfeld D, Lyden PD. PMID: 19893002; PMCID: PMC2819286.
      View in: PubMed   Mentions: 65     Fields:    Translation:Animals
    19. Acute vascular disruption and aquaporin 4 loss after stroke. Stroke. 2009 Jun; 40(6):2182-90. Friedman B, Schachtrup C, Tsai PS, Shih AY, Akassoglou K, Kleinfeld D, Lyden PD. PMID: 19372455; PMCID: PMC2753985.
      View in: PubMed   Mentions: 33     Fields:    Translation:AnimalsCells
    20. Active dilation of penetrating arterioles restores red blood cell flux to penumbral neocortex after focal stroke. J Cereb Blood Flow Metab. 2009 Apr; 29(4):738-51. Shih AY, Friedman B, Drew PJ, Tsai PS, Lyden PD, Kleinfeld D. PMID: 19174826; PMCID: PMC2893883.
      View in: PubMed   Mentions: 65     Fields:    Translation:AnimalsCells
    21. Penetrating arterioles are a bottleneck in the perfusion of neocortex. Proc Natl Acad Sci U S A. 2007 Jan 02; 104(1):365-70. Nishimura N, Schaffer CB, Friedman B, Lyden PD, Kleinfeld D. PMID: 17190804; PMCID: PMC1765467.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimals
    22. Stroke-evoked angiogenesis results in a transient population of microvessels. J Cereb Blood Flow Metab. 2007 Apr; 27(4):755-63. Yu SW, Friedman B, Cheng Q, Lyden PD. PMID: 16883352.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    23. Targeted insult to subsurface cortical blood vessels using ultrashort laser pulses: three models of stroke. Nat Methods. 2006 Feb; 3(2):99-108. Nishimura N, Schaffer CB, Friedman B, Tsai PS, Lyden PD, Kleinfeld D. PMID: 16432519.
      View in: PubMed   Mentions: 143     Fields:    Translation:AnimalsCells
    24. Two-photon imaging of cortical surface microvessels reveals a robust redistribution in blood flow after vascular occlusion. PLoS Biol. 2006 Feb; 4(2):e22. Schaffer CB, Friedman B, Nishimura N, Schroeder LF, Tsai PS, Ebner FF, Lyden PD, Kleinfeld D. PMID: 16379497; PMCID: PMC1324794.
      View in: PubMed   Mentions: 185     Fields:    Translation:Animals
    25. Inhibition of inducible nitric oxide synthase alters Thy-1 glomeruonephritis in rats. Nephron Physiol. 2006; 102(2):p17-26. Satriano J, Lortie MJ, Ishizuka S, Valdivielso JM, Friedman B, Munger KA. PMID: 16230862.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    26. Activation of nucleus basalis facilitates cortical control of a brain stem motor program. J Neurophysiol. 2005 Jul; 94(1):699-711. Berg RW, Friedman B, Schroeder LF, Kleinfeld D. PMID: 15728764.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    27. All-optical histology using ultrashort laser pulses. Neuron. 2003 Jul 03; 39(1):27-41. Tsai PS, Friedman B, Ifarraguerri AI, Thompson BD, Lev-Ram V, Schaffer CB, Xiong Q, Tsien RY, Squier JA, Kleinfeld D. PMID: 12848930.
      View in: PubMed   Mentions: 67     Fields:    Translation:AnimalsCells
    28. Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3. J Biol Chem. 2002 Jul 12; 277(28):25152-9. Ishii I, Ye X, Friedman B, Kawamura S, Contos JJ, Kingsbury MA, Yang AH, Zhang G, Brown JH, Chun J. PMID: 12006579.
      View in: PubMed   Mentions: 95     Fields:    Translation:AnimalsCells
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