Tadeusz Molinski

Title(s)Professor, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    An Integrated Methodology for Nanomole-Scale Structure Elucidation of Natural Products
    NIH R21AT009783Feb 1, 2018 - Jan 31, 2021
    Role: Principal Investigator
    Natural Products for Treatment of Emergent AIDS-Related Pathogens
    NIH R01AI100776Mar 15, 2012 - Feb 28, 2018
    Role: Principal Investigator
    Acquisition of a High Resolution TOF Mass Spectrometer
    NIH S10RR025636Apr 22, 2010 - Apr 21, 2011
    Role: Principal Investigator
    Nanoscale-Natural Products Chemistry
    NIH R01CA122256Jul 22, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Antifungal sphingolipids for AIDS-related Mycoses
    NIH R03TW006301Apr 1, 2003 - Mar 31, 2006
    Role: Principal Investigator
    Natural Product Antitumor Inducers of Apoptosis
    NIH R01CA085602Sep 6, 2002 - Aug 31, 2006
    Role: Principal Investigator
    ACQUISITION OF A QUADRUPOLE ION TRAP-HPLC
    NIH S10RR014701Mar 1, 2000 - Feb 28, 2001
    Role: Principal Investigator
    NOVEL PROBES FOR IMMUNOPHILIN MEDIATED CELL CONTROL
    NIH R01GM057560May 1, 1998 - Apr 30, 2003
    Role: Principal Investigator
    Antifungals from Marine Invertebrates--AIDS Adjuvants
    NIH R01AI039987Mar 1, 1997 - Aug 31, 2012
    Role: Principal Investigator
    ANTIFUNGALS FROM MARINE INVERTEBRATES--AIDS ADJUVANTS
    NIH R21AI039987Sep 1, 1996 - Aug 31, 1997
    Role: Principal Investigator
    MECHANISM-SELECTIVE ANTIFUNGALS--POTENTIAL AIDS ADJUVANT
    NIH R29AI031660Sep 30, 1991 - Nov 30, 1997
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. DFT investigation of coupling constant anomalies in substituted β-lactams. Magn Reson Chem. 2024 Mar 21. Crull EB, Buevich AV, Martin GE, Mahar R, Qu B, Senanayake CH, Molinski TF, Williamson RT. PMID: 38511664.
      View in: PubMed   Mentions:    Fields:    
    2. Orthogonal Deprotection Strategy of Fmoc Provides Improved Synthesis of Sensitive Peptides: Application to Z-Arg-Lys-AOMK. ACS Omega. 2024 Jan 23; 9(3):3997-4003. Almaliti J, Alhindy M, Yoon MC, Hook V, Molinski TF, O'Donoghue AJ, Gerwick WH. PMID: 38284081; PMCID: PMC10809369.
      View in: PubMed   Mentions:
    3. Petrosamine Revisited. Experimental and Computational Investigation of Solvatochromism, Tautomerism and Free Energy Landscapes of a Pyridoacridinium Quaternary Salt. Mar Drugs. 2023 Aug 11; 21(8). Gartshore CJ, Wang X, Su Y, Molinski TF. PMID: 37623727; PMCID: PMC10455967.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    4. Small Molecule in situ Resin Capture - A Compound First Approach to Natural Product Discovery. bioRxiv. 2023 May 30. Bogdanov A, Salib MN, Chase AB, Hammerlindl H, Muskat MN, Luedtke S, Barbosa da Silva E, O'Donoghue AJ, Wu LF, Altschuler SJ, Molinski TF, Jensen PR. PMID: 37398257; PMCID: PMC10312467.
      View in: PubMed   Mentions:
    5. Geobarrettin D, a Rare Herbipoline-Containing 6-Bromoindole Alkaloid from Geodia barretti. Molecules. 2023 Mar 24; 28(7). Di X, Hardardottir I, Freysdottir J, Wang D, Gustafson KR, Omarsdottir S, Molinski TF. PMID: 37049700; PMCID: PMC10095911.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    6. Bioactive Bromotyrosine Alkaloids from the Bahamian Marine Sponge Aiolochroia crassa. Dimerization and Oxidative Motifs. J Org Chem. 2022 10 07; 87(19):12831-12843. Salib MN, Hendra R, Molinski TF. PMID: 36112478.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    7. Spiroisoxazoline Inhibitors of Acetylcholinesterase from Pseudoceratina verrucosa. Quantitative Chiroptical Analysis of Configurational Heterogeneity, and Total Synthesis of (±)-Methyl Purpuroceratate C. J Nat Prod. 2022 09 23; 85(9):2207-2216. Hendra R, Salib MN, Molinski TF. PMID: 36095307.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. Chlororesistoflavins A and B, Chlorinated Benzopyrene Antibiotics Produced by the Marine-Derived Actinomycete Streptomyces sp. Strain EG32. J Nat Prod. 2022 01 28; 85(1):270-275. Kim MC, Li Z, Cullum R, Molinski TF, Eid MAG, Hebishy AMS, Faraag AHI, Abdel Moneim AE, Abdelfattah MS, Fenical W. PMID: 34967630.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    9. Oceanalin B, a Hybrid α,ω-Bifunctionalized Sphingoid Tetrahydroisoquinoline β-Glycoside from the Marine Sponge Oceanapia sp. Mar Drugs. 2021 Nov 12; 19(11). Makarieva TN, Ivanchina NV, Dmitrenok PS, Guzii AG, Stonik VA, Dalisay DS, Molinski TF. PMID: 34822506; PMCID: PMC8618332.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    10. Oceanapiside, a Marine Natural Product, Targets the Sphingolipid Pathway of Fluconazole-Resistant Candida glabrata. Mar Drugs. 2021 Feb 26; 19(3). Dalisay DS, Rogers EW, Molinski TF. PMID: 33652774; PMCID: PMC7996939.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    11. Bromotryptamine and Imidazole Alkaloids with Anti-inflammatory Activity from the Bryozoan Flustra foliacea. J Nat Prod. 2020 10 23; 83(10):2854-2866. Di X, Wang S, Oskarsson JT, Rouger C, Tasdemir D, Hardardottir I, Freysdottir J, Wang X, Molinski TF, Omarsdottir S. PMID: 33016699.
      View in: PubMed   Mentions: 7     Fields:    Translation:Animals
    12. Synchronous bond molecular dynamics of conjugated chlorocyclopropyl alk-yn-enes revealed by ECD and UV-vis. Chirality. 2020 08; 32(8):1037-1044. Skepper CK, Molinski TF. PMID: 32567115.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    13. Bromo-spiroisoxazoline Alkaloids, Including an Isoserine Peptide, from the Caribbean Marine Sponge Aplysina lacunosa. J Nat Prod. 2020 05 22; 83(5):1532-1540. Salib MN, Jamison MT, Molinski TF. PMID: 32357010.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    14. The Configuration of Distaminolyne A is S: Quantitative Evaluation of Exciton Coupling Circular Dichroism of N, O- Bis-arenoyl-1-amino-2-alkanols. J Nat Prod. 2019 05 24; 82(5):1183-1189. Molinski TF, Salib MN, Pearce AN, Copp BR. PMID: 30958674.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    15. Synergistic Anti-Candida Activity of Bengazole A in the Presence of Bengamide A †. Mar Drugs. 2019 Feb 07; 17(2). Jamison MT, Wang X, Cheng T, Molinski TF. PMID: 30736491; PMCID: PMC6410253.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    16. Enantiomeric Variability of Distaminolyne A. Refinement of ECD and NMR Methods for Determining Optical Purity of 1-Amino-2-Alkanols. Molecules. 2018 Dec 27; 24(1). Pearce AN, Copp BR, Molinski TF. PMID: 30591663; PMCID: PMC6337674.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    17. Correction: The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep. 2019 01 01; 36(1):248-249. McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. PMID: 30468235; PMCID: PMC6474672.
      View in: PubMed   Mentions: 2     Fields:    
    18. 6-Bromoindole Derivatives from the Icelandic Marine Sponge Geodia barretti: Isolation and Anti-Inflammatory Activity. Mar Drugs. 2018 Nov 08; 16(11). Di X, Rouger C, Hardardottir I, Freysdottir J, Molinski TF, Tasdemir D, Omarsdottir S. PMID: 30413031; PMCID: PMC6266195.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    19. Lepadins I-K, 3- O-(3'-Methylthio)acryloyloxy-decahydroquinoline Esters from a Bahamian Ascidian Didemnum sp. Assignment of Absolute Stereostructures. J Org Chem. 2018 11 16; 83(22):13670-13677. Ómarsdóttir S, Wang X, Liu HB, Duggan BM, Molinski TF. PMID: 30280573; PMCID: PMC6486817.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    20. Bromopyrrole Alkaloid Inhibitors of the Proteasome Isolated from a Dictyonella sp. Marine Sponge Collected at the Amazon River Mouth. J Nat Prod. 2018 10 26; 81(10):2296-2300. de Souza RTMP, Freire VF, Gubiani JR, Ferreira RO, Trivella DBB, Moraes FC, Paradas WC, Salgado LT, Pereira RC, Amado Filho GM, Ferreira AG, Williams DE, Andersen RJ, Molinski TF, Berlinck RGS. PMID: 30281303.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    21. The value of universally available raw NMR data for transparency, reproducibility, and integrity in natural product research. Nat Prod Rep. 2019 01 01; 36(1):35-107. McAlpine JB, Chen SN, Kutateladze A, MacMillan JB, Appendino G, Barison A, Beniddir MA, Biavatti MW, Bluml S, Boufridi A, Butler MS, Capon RJ, Choi YH, Coppage D, Crews P, Crimmins MT, Csete M, Dewapriya P, Egan JM, Garson MJ, Genta-Jouve G, Gerwick WH, Gross H, Harper MK, Hermanto P, Hook JM, Hunter L, Jeannerat D, Ji NY, Johnson TA, Kingston DGI, Koshino H, Lee HW, Lewin G, Li J, Linington RG, Liu M, McPhail KL, Molinski TF, Moore BS, Nam JW, Neupane RP, Niemitz M, Nuzillard JM, Oberlies NH, Ocampos FMM, Pan G, Quinn RJ, Reddy DS, Renault JH, Rivera-Chávez J, Robien W, Saunders CM, Schmidt TJ, Seger C, Shen B, Steinbeck C, Stuppner H, Sturm S, Taglialatela-Scafati O, Tantillo DJ, Verpoorte R, Wang BG, Williams CM, Williams PG, Wist J, Yue JM, Zhang C, Xu Z, Simmler C, Lankin DC, Bisson J, Pauli GF. PMID: 30003207; PMCID: PMC6350634.
      View in: PubMed   Mentions: 38     Fields:    Translation:Cells
    22. Resolution of Atropisomeric Cyclic Catechol Monoether O-Sulfate Esters by a Molluscan Sulfatase. ACS Omega. 2018 Jul 31; 3(7):7771-7775. Masuno MN, Molinski TF. PMID: 30087921; PMCID: PMC6072249.
      View in: PubMed   Mentions:
    23. Six Trikentrin-like Cyclopentanoindoles from Trikentrion flabelliforme. Absolute Structural Assignment by NMR and ECD. J Org Chem. 2018 02 02; 83(3):1278-1286. Salib MN, Molinski TF. PMID: 29320183; PMCID: PMC6445389.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    24. Liposomal Circular Dichroism (L-CD) of Arenoyl Derivatives of Sphingolipids. Amplification of Cotton Effects in Ordered Lipid Bilayers. Mar Drugs. 2017 Dec 20; 15(12). Molinski TF, Broaddus CD, Morinaka BI. PMID: 29261105; PMCID: PMC5742824.
      View in: PubMed   Mentions:    Fields:    
    25. Cyclic azole-homologated peptides from Marine sponges. Org Biomol Chem. 2017 Dec 19; 16(1):21-29. Molinski TF. PMID: 29210421; PMCID: PMC6350788.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    26. Isolation of bastadin-6-O-sulfate and expedient purifications of bastadins-4, -5 and -6 from extracts of Ianthella basta. Fitoterapia. 2018 Apr; 126:16-21. Gartshore CJ, Salib MN, Renshaw AA, Molinski TF. PMID: 29221701; PMCID: PMC6391048.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    27. Cyclic Hexapeptide Dimers, Antatollamides A and B, from the Ascidian Didemnum molle. A Tryptophan-Derived Auxiliary for l- and d-Amino Acid Assignments. J Org Chem. 2017 10 06; 82(19):10181-10187. Salib MN, Molinski TF. PMID: 28846849; PMCID: PMC6411300.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    28. Synthesis and Structure Revision of Symplocin A. Org Chem Front. 2017 Jun 01; 4(6):995-1004. Shao LP, Si CM, Mao ZY, Zhou W, Molinski TF, Wei BG, Lin GQ. PMID: 31007934; PMCID: PMC6474688.
      View in: PubMed   Mentions: 2  
    29. Band-Selective 2D HSQMBC: A Universal Technique for Detection and Measurement of 35,37Cl Isotope Effects for 13C Nuclei. Org Lett. 2016 10 07; 18(19):4786-4789. Saurí J, Reibarkh M, Zhang T, Cohen RD, Wang X, Molinski TF, Martin GE, Williamson RT. PMID: 27681329.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    30. Structure-activity of antifungal compounds inspired by aminobisabolenes from the sponge Halichondria sp. Bioorg Med Chem Lett. 2016 11 01; 26(21):5244-5246. Jamison MT, Macho J, Molinski TF. PMID: 27720294.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    31. Jamaicensamide A, a Peptide Containing β-Amino-α-keto and Thiazole-Homologated η-Amino Acid Residues from the Sponge Plakina jamaicensis. J Nat Prod. 2016 09 23; 79(9):2243-9. Jamison MT, Molinski TF. PMID: 27547840.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    32. Ultra-high resolution band-selective HSQC for nanomole-scale identification of chlorine-substituted 13 C in natural products drug discovery. Magn Reson Chem. 2017 Apr; 55(4):263-268. Wang X, Duggan BM, Molinski TF. PMID: 26951950; PMCID: PMC6411301.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    33. Peroxide Natural Products from Plakortis zyggompha and the Sponge Association Plakortis halichondrioides-Xestospongia deweerdtae: Antifungal Activity against Cryptococcus gattii. J Nat Prod. 2016 Mar 25; 79(3):555-63. Jamison MT, Dalisay DS, Molinski TF. PMID: 26859086.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    34. Mollenynes B-E from the marine sponge Spirastrella mollis. Band-selective heteronuclear single quantum coherence for discrimination of bromo-chloro regioisomerism in natural products. J Am Chem Soc. 2015 Sep 30; 137(38):12343-51. Wang X, Duggan BM, Molinski TF. PMID: 26336030.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    35. Antipodal crambescin A2 homologues from the marine sponge Pseudaxinella reticulata. Antifungal structure-activity relationships. J Nat Prod. 2015 Mar 27; 78(3):557-61. Jamison MT, Molinski TF. PMID: 25738226.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    36. Cytotoxic effects on tumour cell lines of fatty acids from the marine sponge Scopalina ruetzleri. J Pharm Pharmacol. 2015 May; 67(5):746-53. Biegelmeyer R, Schröder R, Rambo DF, Dresch RR, Stout EP, Carraro JL, Mothes B, Moreira JC, Molinski TF, da Frota Junior ML, Henriques AT. PMID: 25560902.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    37. Salvadenosine, a 5'-deoxy-5'-(methylthio) nucleoside from the Bahamian tunicate Didemnum sp. J Org Chem. 2014 Nov 07; 79(21):9992-7. Jamison MT, Boddy CN, Molinski TF. PMID: 25284474; PMCID: PMC4227578.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    38. All natural: the renaissance of natural products chemistry. J Org Chem. 2014 Aug 01; 79(15):6765. Molinski TF. PMID: 25081028.
      View in: PubMed   Mentions: 1     Fields:    
    39. All natural: the renaissance of natural products chemistry. Org Lett. 2014 Aug 01; 16(15):3849-55. Molinski TF. PMID: 25081565.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    40. Potent fluorinated agelastatin analogues for chronic lymphocytic leukemia: design, synthesis, and pharmacokinetic studies. J Med Chem. 2014 Jun 26; 57(12):5085-93. Stout EP, Choi MY, Castro JE, Molinski TF. PMID: 24673739; PMCID: PMC4079331.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    41. Structures and solution conformational dynamics of stylissamides G and H from the Bahamian sponge Stylissa caribica. J Nat Prod. 2014 Mar 28; 77(3):625-30. Wang X, Morinaka BI, Molinski TF. PMID: 24576291; PMCID: PMC3993948.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    42. Acremolin from Acremonium strictum is N(2),3-etheno-2'-isopropyl-1-methylguanine, not a 1H-azirine. Synthesis and structural revision. Org Lett. 2013 May 17; 15(10):2370-3. Januar LA, Molinski TF. PMID: 23635003; PMCID: PMC3957326.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    43. Temperature-dependent conformations of a membrane supported zinc porphyrin tweezer by 2D fluorescence spectroscopy. J Phys Chem A. 2013 Jul 25; 117(29):6171-84. Widom JR, Lee W, Perdomo-Ortiz A, Rappoport D, Molinski TF, Aspuru-Guzik A, Marcus AH. PMID: 23480874; PMCID: PMC3723700.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    44. D-Glucosamine-derived synthons for assembly of L-threo-sphingoid bases. Total synthesis of rhizochalinin C. J Org Chem. 2013 Jan 18; 78(2):498-505. Ko J, Molinski TF. PMID: 23227909; PMCID: PMC3548972.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    45. Halisphingosines A and B, modified sphingoid bases from Haliclona tubifera. Assignment of configuration by circular dichroism and van't Hoff's principle of optical superposition. J Nat Prod. 2013 Mar 22; 76(3):374-81. Molinski TF, Biegelmeyer R, Stout EP, Wang X, Frota ML, Henriques AT. PMID: 23268569; PMCID: PMC3969749.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    46. INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS. Tetrahedron. 2012 Nov 18; 68(46):9307-9343. Molinski TF, Morinaka BI. PMID: 23814320; PMCID: PMC3694619.
      View in: PubMed   Mentions: 16     Fields:    
    47. Antifungal Diterpene Alkaloids from the Caribbean Sponge Agelas citrina: Unified Configurational Assignments of Agelasidines and Agelasines. European J Org Chem. 2012 Sep; 2012(27):5131-5135. Stout EP, Yu LC, Molinski TF. PMID: 24653665; PMCID: PMC3957321.
      View in: PubMed   Mentions: 18  
    48. Increased resting intracellular calcium modulates NF-κB-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes. J Biol Chem. 2012 Jun 15; 287(25):20876-87. Altamirano F, López JR, Henríquez C, Molinski T, Allen PD, Jaimovich E. PMID: 22549782; PMCID: PMC3375511.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    49. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8. Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski TF, López JR, Beam KG, Allen PD. PMID: 22547813; PMCID: PMC3356662.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    50. Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica. Angew Chem Int Ed Engl. 2012 May 14; 51(20):4877-81. Stout EP, Wang YG, Romo D, Molinski TF. PMID: 22473581; PMCID: PMC3917718.
      View in: PubMed   Mentions: 23     Fields:    Translation:Animals
    51. De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis. J Nat Prod. 2012 Apr 27; 75(4):527-30. Stout EP, Morinaka BI, Wang YG, Romo D, Molinski TF. PMID: 22455452; PMCID: PMC3694594.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    52. Symplocin A, a linear peptide from the Bahamian cyanobacterium Symploca sp. Configurational analysis of N,N-dimethylamino acids by chiral-phase HPLC of naphthacyl esters. J Nat Prod. 2012 Mar 23; 75(3):425-31. Molinski TF, Reynolds KA, Morinaka BI. PMID: 22360587; PMCID: PMC3694611.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    53. Mollenyne A, a long-chain chlorodibromohydrin amide from the sponge Spirastrella mollis. Org Lett. 2011 Dec 16; 13(24):6338-41. Morinaka BI, Molinski TF. PMID: 22087509; PMCID: PMC3544366.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    54. Assembly of the isoindolinone core of muironolide A by asymmetric intramolecular Diels-Alder cycloaddition. Org Lett. 2011 Aug 05; 13(15):3932-5. Flores B, Molinski TF. PMID: 21751773; PMCID: PMC4000739.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    55. Preparation of α-amino acids by oxidative oxazoline-oxazinone rearrangement-hydrogenation (OOOH). Scope and limitations. Chem Asian J. 2011 Aug 01; 6(8):2022-7. Liu C, Molinski TF. PMID: 21751407.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    56. Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues. Tetrahedron. 2011 Jul 08; 67(27-28):5069-5078. Smith AB, Hogan AM, Liu Z, Razler TM, Meis RM, Morinaka BI, Molinski TF. PMID: 21811346; PMCID: PMC3146768.
      View in: PubMed   Mentions: 2     Fields:    
    57. Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans. Bioorg Med Chem. 2011 Nov 15; 19(22):6654-7. Dalisay DS, Saludes JP, Molinski TF. PMID: 21715177; PMCID: PMC3523195.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    58. Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7046-51. Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR. PMID: 21482776; PMCID: PMC3084091.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    59. N,N'-methyleno-didemnin A from the ascidian Trididemnum solidum. Complete NMR assignments and confirmation of the imidazolidinone ring by strategic analysis of 1J(CH). J Nat Prod. 2011 Apr 25; 74(4):882-7. Molinski TF, Ko J, Reynolds KA, Lievens SC, Skarda KR. PMID: 21341712; PMCID: PMC3694603.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    60. Xestoproxamines A-C from Neopetrosia proxima. Assignment of absolute stereostructure of bis-piperidine alkaloids by integrated degradation-CD analysis. J Nat Prod. 2011 Mar 25; 74(3):430-40. Morinaka BI, Molinski TF. PMID: 21341726; PMCID: PMC3957325.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    61. Faulknerynes A-C from a Bahamian sponge Diplastrella sp.: stereoassignment by critical application of two exciton coupled CD methods. J Org Chem. 2011 Feb 04; 76(3):894-901. Ko J, Morinaka BI, Molinski TF. PMID: 21218782; PMCID: PMC3523196.
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    62. Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62. Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski TF, Fruen BR, Allen PD, Perez CF. PMID: 20926377; PMCID: PMC2992278.
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    64. Total synthesis of enigmazole A from Cinachyrella enigmatica. Bidirectional bond constructions with an ambident 2,4-disubstituted oxazole synthon. J Am Chem Soc. 2010 Aug 04; 132(30):10286-92. Skepper CK, Quach T, Molinski TF. PMID: 20590095.
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    66. Amaranzoles B-F, imidazole-2-carboxy steroids from the marine sponge Phorbas amaranthus. C24-N- and C24-O-analogues from a divergent oxidative biosynthesis. J Org Chem. 2010 Apr 16; 75(8):2453-60. Morinaka BI, Pawlik JR, Molinski TF. PMID: 20235564; PMCID: PMC2852487.
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    67. Liposomal circular dichroism. Assignment of remote stereocenters in plakinic acids K and L from a Plakortis-Xestospongia sponge association. Org Lett. 2010 Apr 02; 12(7):1524-7. Dalisay DS, Quach T, Molinski TF. PMID: 20205426; PMCID: PMC2846192.
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    69. Diastereoselective allylstannane additions to (S)-5,6-dihydro-2H-5-phenyloxazin-2-one. A concise synthesis of (S)-beta-methylisoleucine. Org Lett. 2010 Mar 19; 12(6):1256-9. Pigza JA, Molinski TF. PMID: 20163126; PMCID: PMC2837769.
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    73. Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine. Bioorg Med Chem Lett. 2010 Mar 15; 20(6):2029-32. Skepper CK, Dalisay DS, Molinski TF. PMID: 20171099; PMCID: PMC2834865.
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    75. (+)-Zwittermicin A. Rapid assembly of C9-C15 and a formal total synthesis. J Org Chem. 2009 Oct 16; 74(20):7660-4. Rogers EW, Molinski TF. PMID: 19746943; PMCID: PMC2759841.
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    76. Hemi-phorboxazole a: structure confirmation, analogue design and biological evaluation. Org Lett. 2009 Aug 20; 11(16):3766-9. Smith AB, Liu Z, Hogan AM, Dalisay DS, Molinski TF. PMID: 19637861; PMCID: PMC2743491.
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    77. Oxazoline-oxazinone oxidative rearrangement. divergent syntheses of (2S,3S)-4,4,4-trifluorovaline and (2S,4S)-5,5,5-Trifluoroleucine. J Org Chem. 2009 Aug 07; 74(15):5510-5. Pigza JA, Quach T, Molinski TF. PMID: 19537688.
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    78. A tetrachloro polyketide hexahydro-1H-isoindolone, muironolide A, from the marine sponge Phorbas sp. natural products at the nanomole scale. J Am Chem Soc. 2009 Jun 10; 131(22):7552-3. Dalisay DS, Morinaka BI, Skepper CK, Molinski TF. PMID: 19453148.
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    79. Marine natural products. Clin Adv Hematol Oncol. 2009 Jun; 7(6):383-5. Molinski T. PMID: 19606073.
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    83. Structure elucidation at the nanomole scale. 1. Trisoxazole macrolides and thiazole-containing cyclic peptides from the nudibranch Hexabranchus sanguineus. J Nat Prod. 2009 Apr; 72(4):732-8. Dalisay DS, Rogers EW, Edison AS, Molinski TF. PMID: 19254038; PMCID: PMC2753413.
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    84. Absolute configuration of the alpha,omega-bifunctionalized sphingolipid leucettamol A from Leucetta microrhaphis by deconvoluted exciton coupled CD. J Nat Prod. 2009 Mar 27; 72(3):353-9. Dalisay DS, Tsukamoto S, Molinski TF. PMID: 19159253; PMCID: PMC2765480.
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    85. Nanomole-scale natural products discovery. Curr Opin Drug Discov Devel. 2009 Mar; 12(2):197-206. Molinski TF. PMID: 19333865.
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    86. Amaroxocanes A and B: sulfated dimeric sterols defend the Caribbean coral reef sponge Phorbas amaranthus from fish predators. J Nat Prod. 2009 Feb 27; 72(2):259-64. Morinaka BI, Pawlik JR, Molinski TF. PMID: 19143510.
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    87. Amplification of the Cotton effect of a single chromophore through liposomal ordering-stereochemical assignment of plakinic acids I and J. Angew Chem Int Ed Engl. 2009; 48(24):4367-71. Dalisay DS, Quach T, Nicholas GN, Molinski TF. PMID: 19437515; PMCID: PMC2872062.
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    88. Drug development from marine natural products. Nat Rev Drug Discov. 2009 Jan; 8(1):69-85. Molinski TF, Dalisay DS, Lievens SL, Saludes JP. PMID: 19096380.
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    89. Synthesis and antifungal activity of (-)-(Z)-dysidazirine. Org Lett. 2008 Nov 20; 10(22):5269-71. Skepper CK, Dalisay DS, Molinski TF. PMID: 18937483; PMCID: PMC2635126.
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    90. Exciton coupling circular dichroism of an allylic N-imidazolyl group in amaranzole A, a marine natural product from Phorbas amaranthus. Chirality. 2008 Sep; 20(9):1066-70. Morinaka BI, Molinski TF. PMID: 18690668; PMCID: PMC2615005.
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    91. Phorbasides A-E, cytotoxic chlorocyclopropane macrolide glycosides from the marine sponge Phorbas sp. CD determination of C-methyl sugar configurations. J Org Chem. 2008 May 16; 73(10):3699-706. MacMillan JB, Xiong-Zhou G, Skepper CK, Molinski TF. PMID: 18412387.
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    92. Long-chain 2H-azirines with heterogeneous terminal halogenation from the marine sponge Dysidea fragilis. J Org Chem. 2008 Apr 04; 73(7):2592-7. Skepper CK, Molinski TF. PMID: 18321120.
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    93. Store-operated Ca2+ influx causes Ca2+ release from the intracellular Ca2+ channels that is required for T cell activation. J Biol Chem. 2008 May 02; 283(18):12512-9. Dadsetan S, Zakharova L, Molinski TF, Fomina AF. PMID: 18316371.
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    94. (+)-Zwittermicin A: assignment of its complete configuration by total synthesis of the enantiomer and implication of D-serine in its biosynthesis. Angew Chem Int Ed Engl. 2008; 47(42):8086-9. Rogers EW, Dalisay DS, Molinski TF. PMID: 18798190; PMCID: PMC3957322.
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    95. Rhizochalins C and D from the sponge Rhizochalina incrustata. A rare threo-sphingolipid and a facile method for determination of the carbonyl position in alpha,omega-bifunctionalized ketosphingolipids. J Nat Prod. 2007 Dec; 70(12):1991-8. Makarieva TN, Dmitrenok PS, Zakharenko AM, Denisenko VA, Guzii AG, Li R, Skepper CK, Molinski TF, Stonik VA. PMID: 18052325.
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    96. Stereochemistry of sagittamide A from residual dipolar coupling enhanced NMR. J Am Chem Soc. 2007 Dec 12; 129(49):15114-5. Schuetz A, Junker J, Leonov A, Lange OF, Molinski TF, Griesinger C. PMID: 17999506.
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    99. Ene-yne tetrahydrofurans from the sponge Xestospongia muta. exploiting a weak CD effect for assignment of configuration. Org Lett. 2007 May 10; 9(10):1975-8. Morinaka BI, Skepper CK, Molinski TF. PMID: 17439137.
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    101. Occurrence of the alpha-glucosidase inhibitor 1,4-Dideoxy-1,4-imino-D-arabinitol and related iminopentitols in marine sponges. J Nat Prod. 2007 Mar; 70(3):436-8. Saludes JP, Lievens SC, Molinski TF. PMID: 17378534.
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    103. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8. Yang T, Esteve E, Pessah IN, Molinski TF, Allen PD, López JR. PMID: 17182726.
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    106. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. J Nat Prod. 2006 Feb; 69(2):173-7. Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski TF, van Soest R, Andersen RJ. PMID: 16499312.
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    108. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors. Mol Pharmacol. 2006 Feb; 69(2):532-8. Ta TA, Feng W, Molinski TF, Pessah IN. PMID: 16249374.
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    109. Oceanalin A, a hybrid alpha,omega-bifunctionalized sphingoid tetrahydroisoquinoline beta-glycoside from the marine sponge Oceanapia sp. Org Lett. 2005 Jul 07; 7(14):2897-900. Makarieva TN, Denisenko VA, Dmitrenok PS, Guzii AG, Santalova EA, Stonik VA, Macmillan JB, Molinski TF. PMID: 15987164.
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    112. Addition of Cl2C: to (-)-O-menthyl acrylate under sonication-phase-transfer catalysis. Efficient synthesis of (+)- and (-)-(2-chlorocyclopropyl)methanol. J Org Chem. 2005 May 13; 70(10):4162-5. Masuno MN, Young DM, Hoepker AC, Skepper CK, Molinski TF. PMID: 15876110.
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    118. Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. Angew Chem Int Ed Engl. 2004 Nov 12; 43(44):5946-51. Macmillan JB, Linington RG, Andersen RJ, Molinski TF. PMID: 15547902.
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    119. Enantioselective total synthesis of (+)-milnamide A and evidence of its autoxidation to (+)-milnamide D. Angew Chem Int Ed Engl. 2004 Nov 12; 43(44):5951-4. Liu C, Masuno MN, Macmillan JB, Molinski TF. PMID: 15547903.
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    138. Bastadins relate ryanodine-sensitive and -insensitive Ca2+ efflux pathways in skeletal SR and BC3H1 cells. Am J Physiol. 1997 Feb; 272(2 Pt 1):C601-14. Pessah IN, Molinski TF, Meloy TD, Wong P, Buck ED, Allen PD, Mohr FC, Mack MM. PMID: 9124304.
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    139. Bastadin 20 and bastadin O-sulfate esters from Ianthella basta: novel modulators of the Ry1R FKBP12 receptor complex. J Nat Prod. 1996 Dec; 59(12):1121-7. Franklin MA, Penn SG, Lebrilla CB, Lam TH, Pessah IN, Molinski TF. PMID: 8988595.
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    140. A psychrophilic crenarchaeon inhabits a marine sponge: Cenarchaeum symbiosum gen. nov., sp. nov. Proc Natl Acad Sci U S A. 1996 Jun 25; 93(13):6241-6. Preston CM, Wu KY, Molinski TF, DeLong EF. PMID: 8692799; PMCID: PMC39006.
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    141. Exact mass determination for elemental analysis of ions produced by matrix-assisted laser desorption. Anal Chem. 1995 Oct 15; 67(20):3788-92. Wu J, Fannin ST, Franklin MA, Molinski TF, Lebrilla CB. PMID: 8644924.
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    142. 4-Dehydroecdysterone, a new ecdysteroid from the zoanthid Parazoanthus sp. J Nat Prod. 1995 Feb; 58(2):264-8. Searle PA, Molinski TF. PMID: 7769393.
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    143. Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Role of FKBP12 in channel gating. J Biol Chem. 1994 Sep 16; 269(37):23236-49. Mack MM, Molinski TF, Buck ED, Pessah IN. PMID: 8083229.
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    144. Screening of marine invertebrates for the presence of ergosterol-sensitive antifungal compounds. J Nat Prod. 1993 Jan; 56(1):54-61. Antonio J, Molinski TF. PMID: 8450321.
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    145. Developments in marine natural products. Receptor-specific bioactive compounds. J Nat Prod. 1993 Jan; 56(1):1-8. Molinski TF. PMID: 8450313.
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    146. Oxidation of peptidyl 3,4-dihydroxyphenylalanine analogues: implications for the biosynthesis of tunichromes and related oligopeptides. J Nat Prod. 1991 May-Jun; 54(3):918-22. Taylor SW, Molinski TF, Rzepecki LM, Waite JH. PMID: 1955891.
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    147. Antifeedant activity againstSpodoptera litera larvae and [(13)C]NMR spectral assignments of the meliatoxins. J Chem Ecol. 1990 Aug; 16(8):2511-8. Macleod JK, Moeller PD, Molinski TF, Koul O. PMID: 24264216.
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