Loading...

Tadeusz Molinski

TitleAdjunct Professor
InstitutionUniversity of California San Diego
DepartmentCenter for Marine Biotechnology and Biomedecine
Address9500 Gilman Drive #0358
La Jolla CA 92093
Phone858-534-7115
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    An Integrated Methodology for Nanomole-Scale Structure Elucidation of Natural Products
    NIH/NCCIH R21AT009783Feb 1, 2018 - Jan 31, 2020
    Role: Principal Investigator
    Natural Products for Treatment of Emergent AIDS-Related Pathogens
    NIH/NIAID R01AI100776Mar 15, 2012 - Feb 28, 2017
    Role: Principal Investigator
    Acquisition of a High Resolution TOF Mass Spectrometer
    NIH/NCRR S10RR025636Apr 22, 2010 - Apr 21, 2011
    Role: Principal Investigator
    Nanoscale-Natural Products Chemistry
    NIH/NCI R01CA122256Jul 22, 2006 - Jun 30, 2011
    Role: Principal Investigator
    Antifungal sphingolipids for AIDS-related Mycoses
    NIH/FIC R03TW006301Apr 1, 2003 - Mar 31, 2006
    Role: Principal Investigator
    Natural Product Antitumor Inducers of Apoptosis
    NIH/NCI R01CA085602Sep 6, 2002 - Aug 31, 2006
    Role: Principal Investigator
    ACQUISITION OF A QUADRUPOLE ION TRAP-HPLC
    NIH/NCRR S10RR014701Mar 1, 2000 - Feb 28, 2001
    Role: Principal Investigator
    NOVEL PROBES FOR IMMUNOPHILIN MEDIATED CELL CONTROL
    NIH/NIGMS R01GM057560May 1, 1998 - Apr 30, 2003
    Role: Principal Investigator
    Antifungals from Marine Invertebrates--AIDS Adjuvants
    NIH/NIAID R01AI039987Mar 1, 1997 - Aug 31, 2012
    Role: Principal Investigator
    ANTIFUNGALS FROM MARINE INVERTEBRATES--AIDS ADJUVANTS
    NIH/NIAID R21AI039987Sep 1, 1996 - Aug 31, 1997
    Role: Principal Investigator
    MECHANISM-SELECTIVE ANTIFUNGALS--POTENTIAL AIDS ADJUVANT
    NIH/NIAID R29AI031660Sep 30, 1991 - Nov 30, 1997
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Salib MN, Molinski T. Six Trikentrin-like Cyclopentanoindoles from Trikentrion flabelliforme. Absolute Structural Assignment by NMR and ECD. J Org Chem. 2018 02 02; 83(3):1278-1286. PMID: 29320183.
      View in: PubMed
    2. Molinski T, Broaddus CD, Morinaka BI. Liposomal Circular Dichroism (L-CD) of Arenoyl Derivatives of Sphingolipids. Amplification of Cotton Effects in Ordered Lipid Bilayers. Mar Drugs. 2017 Dec 20; 15(12). PMID: 29261105.
      View in: PubMed
    3. Molinski T. Cyclic azole-homologated peptides from Marine sponges. Org Biomol Chem. 2017 Dec 19; 16(1):21-29. PMID: 29210421.
      View in: PubMed
    4. Gartshore CJ, Salib MN, Renshaw AA, Molinski T. Isolation of bastadin-6-O-sulfate and expedient purifications of bastadins-4, -5 and -6 from extracts of Ianthella basta. Fitoterapia. 2018 Apr; 126:16-21. PMID: 29221701.
      View in: PubMed
    5. Salib MN, Molinski T. Cyclic Hexapeptide Dimers, Antatollamides A and B, from the Ascidian Didemnum molle. A Tryptophan-Derived Auxiliary for l- and d-Amino Acid Assignments. J Org Chem. 2017 Oct 06; 82(19):10181-10187. PMID: 28846849.
      View in: PubMed
    6. Saurí J, Reibarkh M, Zhang T, Cohen RD, Wang X, Molinski T, Martin GE, Williamson RT. Band-Selective 2D HSQMBC: A Universal Technique for Detection and Measurement of 35,37Cl Isotope Effects for 13C Nuclei. Org Lett. 2016 Oct 07; 18(19):4786-4789. PMID: 27681329.
      View in: PubMed
    7. Jamison MT, Macho J, Molinski T. Structure-activity of antifungal compounds inspired by aminobisabolenes from the sponge Halichondria sp. Bioorg Med Chem Lett. 2016 11 01; 26(21):5244-5246. PMID: 27720294.
      View in: PubMed
    8. Jamison MT, Molinski T. Jamaicensamide A, a Peptide Containing ß-Amino-a-keto and Thiazole-Homologated ?-Amino Acid Residues from the Sponge Plakina jamaicensis. J Nat Prod. 2016 09 23; 79(9):2243-9. PMID: 27547840.
      View in: PubMed
    9. Wang X, Duggan BM, Molinski T. Ultra-high resolution band-selective HSQC for nanomole-scale identification of chlorine-substituted 13 C in natural products drug discovery. Magn Reson Chem. 2017 Apr; 55(4):263-268. PMID: 26951950.
      View in: PubMed
    10. Jamison MT, Dalisay DS, Molinski T. Peroxide Natural Products from Plakortis zyggompha and the Sponge Association Plakortis halichondrioides-Xestospongia deweerdtae: Antifungal Activity against Cryptococcus gattii. J Nat Prod. 2016 Mar 25; 79(3):555-63. PMID: 26859086.
      View in: PubMed
    11. Wang X, Duggan BM, Molinski T. Mollenynes B-E from the marine sponge Spirastrella mollis. Band-selective heteronuclear single quantum coherence for discrimination of bromo-chloro regioisomerism in natural products. J Am Chem Soc. 2015 Sep 30; 137(38):12343-51. PMID: 26336030.
      View in: PubMed
    12. Jamison MT, Molinski T. Antipodal crambescin A2 homologues from the marine sponge Pseudaxinella reticulata. Antifungal structure-activity relationships. J Nat Prod. 2015 Mar 27; 78(3):557-61. PMID: 25738226.
      View in: PubMed
    13. Biegelmeyer R, Schröder R, Rambo DF, Dresch RR, Stout EP, Carraro JL, Mothes B, Moreira JC, Molinski T, da Frota Junior ML, Henriques AT. Cytotoxic effects on tumour cell lines of fatty acids from the marine sponge Scopalina ruetzleri. J Pharm Pharmacol. 2015 May; 67(5):746-53. PMID: 25560902.
      View in: PubMed
    14. Jamison MT, Boddy CN, Molinski T. Salvadenosine, a 5'-deoxy-5'-(methylthio) nucleoside from the Bahamian tunicate Didemnum sp. J Org Chem. 2014 Nov 07; 79(21):9992-7. PMID: 25284474; PMCID: PMC4227578.
    15. Molinski T. All natural: the renaissance of natural products chemistry. Org Lett. 2014 Aug 01; 16(15):3849-55. PMID: 25081565.
      View in: PubMed
    16. Molinski T. All natural: the renaissance of natural products chemistry. J Org Chem. 2014 Aug 01; 79(15):6765. PMID: 25081028.
      View in: PubMed
    17. Stout EP, Choi MY, Castro JE, Molinski T. Potent fluorinated agelastatin analogues for chronic lymphocytic leukemia: design, synthesis, and pharmacokinetic studies. J Med Chem. 2014 Jun 26; 57(12):5085-93. PMID: 24673739; PMCID: PMC4079331.
    18. Wang X, Morinaka BI, Molinski T. Structures and solution conformational dynamics of stylissamides G and H from the Bahamian sponge Stylissa caribica. J Nat Prod. 2014 Mar 28; 77(3):625-30. PMID: 24576291; PMCID: PMC3993948.
    19. Januar LA, Molinski T. Acremolin from Acremonium strictum is N(2),3-etheno-2'-isopropyl-1-methylguanine, not a 1H-azirine. Synthesis and structural revision. Org Lett. 2013 May 17; 15(10):2370-3. PMID: 23635003; PMCID: PMC3957326.
    20. Widom JR, Lee W, Perdomo-Ortiz A, Rappoport D, Molinski T, Aspuru-Guzik A, Marcus AH. Temperature-dependent conformations of a membrane supported zinc porphyrin tweezer by 2D fluorescence spectroscopy. J Phys Chem A. 2013 Jul 25; 117(29):6171-84. PMID: 23480874; PMCID: PMC3723700.
    21. Ko J, Molinski T. D-Glucosamine-derived synthons for assembly of L-threo-sphingoid bases. Total synthesis of rhizochalinin C. J Org Chem. 2013 Jan 18; 78(2):498-505. PMID: 23227909; PMCID: PMC3548972.
    22. Molinski T, Biegelmeyer R, Stout EP, Wang X, Frota ML, Henriques AT. Halisphingosines A and B, modified sphingoid bases from Haliclona tubifera. Assignment of configuration by circular dichroism and van't Hoff's principle of optical superposition. J Nat Prod. 2013 Mar 22; 76(3):374-81. PMID: 23268569; PMCID: PMC3969749.
    23. Molinski T, Morinaka BI. INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTS. Tetrahedron. 2012 Nov 18; 68(46):9307-9343. PMID: 23814320.
      View in: PubMed
    24. Stout EP, Yu LC, Molinski T. Antifungal Diterpene Alkaloids from the Caribbean Sponge Agelas citrina: Unified Configurational Assignments of Agelasidines and Agelasines. European J Org Chem. 2012 Sep; 2012(27):5131-5135. PMID: 24653665.
      View in: PubMed
    25. Altamirano F, López JR, Henríquez C, Molinski T, Allen PD, Jaimovich E. Increased resting intracellular calcium modulates NF-?B-dependent inducible nitric-oxide synthase gene expression in dystrophic mdx skeletal myotubes. J Biol Chem. 2012 Jun 15; 287(25):20876-87. PMID: 22549782; PMCID: PMC3375511.
    26. Eltit JM, Bannister RA, Moua O, Altamirano F, Hopkins PM, Pessah IN, Molinski T, López JR, Beam KG, Allen PD. Malignant hyperthermia susceptibility arising from altered resting coupling between the skeletal muscle L-type Ca2+ channel and the type 1 ryanodine receptor. Proc Natl Acad Sci U S A. 2012 May 15; 109(20):7923-8. PMID: 22547813; PMCID: PMC3356662.
    27. Stout EP, Wang YG, Romo D, Molinski T. Pyrrole aminoimidazole alkaloid metabiosynthesis with marine sponges Agelas conifera and Stylissa caribica. Angew Chem Int Ed Engl. 2012 May 14; 51(20):4877-81. PMID: 22473581; PMCID: PMC3917718.
    28. Stout EP, Morinaka BI, Wang YG, Romo D, Molinski T. De novo synthesis of benzosceptrin C and nagelamide H from 7-15N-oroidin: implications for pyrrole-aminoimidazole alkaloid biosynthesis. J Nat Prod. 2012 Apr 27; 75(4):527-30. PMID: 22455452; PMCID: PMC3694594.
    29. Molinski T, Reynolds KA, Morinaka BI. Symplocin A, a linear peptide from the Bahamian cyanobacterium Symploca sp. Configurational analysis of N,N-dimethylamino acids by chiral-phase HPLC of naphthacyl esters. J Nat Prod. 2012 Mar 23; 75(3):425-31. PMID: 22360587; PMCID: PMC3694611.
    30. Morinaka BI, Molinski T. Mollenyne A, a long-chain chlorodibromohydrin amide from the sponge Spirastrella mollis. Org Lett. 2011 Dec 16; 13(24):6338-41. PMID: 22087509; PMCID: PMC3544366.
    31. Flores B, Molinski T. Assembly of the isoindolinone core of muironolide A by asymmetric intramolecular Diels-Alder cycloaddition. Org Lett. 2011 Aug 05; 13(15):3932-5. PMID: 21751773; PMCID: PMC4000739.
    32. Liu C, Molinski T. Preparation of a-amino acids by oxidative oxazoline-oxazinone rearrangement-hydrogenation (OOOH). Scope and limitations. Chem Asian J. 2011 Aug 01; 6(8):2022-7. PMID: 21751407.
      View in: PubMed
    33. Smith AB, Hogan AM, Liu Z, Razler TM, Meis RM, Morinaka BI, Molinski T. Phorboxazole Synthetic Studies: Design, Synthesis and Biological Evaluation of Phorboxazole A and Hemi-Phorboxazole A Related Analogues. Tetrahedron. 2011 Jul 08; 67(27-28):5069-5078. PMID: 21811346.
      View in: PubMed
    34. Dalisay DS, Saludes JP, Molinski T. Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans. Bioorg Med Chem. 2011 Nov 15; 19(22):6654-7. PMID: 21715177; PMCID: PMC3523195.
    35. Eltit JM, Li H, Ward CW, Molinski T, Pessah IN, Allen PD, Lopez JR. Orthograde dihydropyridine receptor signal regulates ryanodine receptor passive leak. Proc Natl Acad Sci U S A. 2011 Apr 26; 108(17):7046-51. PMID: 21482776; PMCID: PMC3084091.
    36. Morinaka BI, Molinski T. Xestoproxamines A-C from Neopetrosia proxima. Assignment of absolute stereostructure of bis-piperidine alkaloids by integrated degradation-CD analysis. J Nat Prod. 2011 Mar 25; 74(3):430-40. PMID: 21341726; PMCID: PMC3957325.
    37. Molinski T, Ko J, Reynolds KA, Lievens SC, Skarda KR. N,N'-methyleno-didemnin A from the ascidian Trididemnum solidum. Complete NMR assignments and confirmation of the imidazolidinone ring by strategic analysis of 1J(CH). J Nat Prod. 2011 Apr 25; 74(4):882-7. PMID: 21341712; PMCID: PMC3694603.
    38. Ko J, Morinaka BI, Molinski T. Faulknerynes A-C from a Bahamian sponge Diplastrella sp.: stereoassignment by critical application of two exciton coupled CD methods. J Org Chem. 2011 Feb 04; 76(3):894-901. PMID: 21218782; PMCID: PMC3523196.
    39. Eltit JM, Feng W, Lopez JR, Padilla IT, Pessah IN, Molinski T, Fruen BR, Allen PD, Perez CF. Ablation of skeletal muscle triadin impairs FKBP12/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2+. J Biol Chem. 2010 Dec 03; 285(49):38453-62. PMID: 20926377; PMCID: PMC2992278.
    40. Molinski T. Microscale methodology for structure elucidation of natural products. Curr Opin Biotechnol. 2010 Dec; 21(6):819-26. PMID: 20880694; PMCID: PMC2982861.
    41. Skepper CK, Quach T, Molinski T. Total synthesis of enigmazole A from Cinachyrella enigmatica. Bidirectional bond constructions with an ambident 2,4-disubstituted oxazole synthon. J Am Chem Soc. 2010 Aug 04; 132(30):10286-92. PMID: 20590095.
      View in: PubMed
    42. Dalisay DS, Molinski T. Structure elucidation at the nanomole scale. 3. Phorbasides G-I from Phorbas sp. J Nat Prod. 2010 Apr 23; 73(4):679-82. PMID: 20184337; PMCID: PMC2859111.
    43. Morinaka BI, Pawlik JR, Molinski T. Amaranzoles B-F, imidazole-2-carboxy steroids from the marine sponge Phorbas amaranthus. C24-N- and C24-O-analogues from a divergent oxidative biosynthesis. J Org Chem. 2010 Apr 16; 75(8):2453-60. PMID: 20235564; PMCID: PMC2852487.
    44. Dalisay DS, Quach T, Molinski T. Liposomal circular dichroism. Assignment of remote stereocenters in plakinic acids K and L from a Plakortis-Xestospongia sponge association. Org Lett. 2010 Apr 02; 12(7):1524-7. PMID: 20205426; PMCID: PMC2846192.
    45. Wang YG, Morinaka BI, Reyes JC, Wolff JJ, Romo D, Molinski T. Synthesis of 7-(15)N-Oroidin and evaluation of utility for biosynthetic studies of pyrrole-imidazole alkaloids by microscale (1)H-(15)N HSQC and FTMS. J Nat Prod. 2010 Mar 26; 73(3):428-34. PMID: 20095632; PMCID: PMC3544367.
    46. Pigza JA, Molinski T. Diastereoselective allylstannane additions to (S)-5,6-dihydro-2H-5-phenyloxazin-2-one. A concise synthesis of (S)-beta-methylisoleucine. Org Lett. 2010 Mar 19; 12(6):1256-9. PMID: 20163126; PMCID: PMC2837769.
    47. Eltit JM, Yang T, Li H, Molinski T, Pessah IN, Allen PD, Lopez JR. RyR1-mediated Ca2+ leak and Ca2+ entry determine resting intracellular Ca2+ in skeletal myotubes. J Biol Chem. 2010 Apr 30; 285(18):13781-7. PMID: 20207743; PMCID: PMC2859541.
    48. Rogers EW, Dalisay DS, Molinski T. Zwittermicin A: synthesis of analogs and structure-activity studies. Bioorg Med Chem Lett. 2010 Apr 01; 20(7):2183-5. PMID: 20189808; PMCID: PMC2845154.
    49. Molinski T. NMR of natural products at the 'nanomole-scale'. Nat Prod Rep. 2010 Mar; 27(3):321-9. PMID: 20179874.
      View in: PubMed
    50. Skepper CK, Dalisay DS, Molinski T. Synthesis and chain-dependent antifungal activity of long-chain 2H-azirine-carboxylate esters related to dysidazirine. Bioorg Med Chem Lett. 2010 Mar 15; 20(6):2029-32. PMID: 20171099; PMCID: PMC2834865.
    51. Makarieva TN, Zakharenko AM, Dmitrenok PS, Guzii AG, Denisenko VA, Savina AS, Dalisay DS, Molinski T, Stonik VA. Isorhizochalin: a minor unprecedented bipolar sphingolipid of stereodivergent biogenesis from the Rhizochalina incrustata. Lipids. 2009 Dec; 44(12):1155-62. PMID: 19882184.
      View in: PubMed
    52. Rogers EW, Molinski T. (+)-Zwittermicin A. Rapid assembly of C9-C15 and a formal total synthesis. J Org Chem. 2009 Oct 16; 74(20):7660-4. PMID: 19746943; PMCID: PMC2759841.
    53. Smith AB, Liu Z, Hogan AM, Dalisay DS, Molinski T. Hemi-phorboxazole a: structure confirmation, analogue design and biological evaluation. Org Lett. 2009 Aug 20; 11(16):3766-9. PMID: 19637861; PMCID: PMC2743491.
    54. Pigza JA, Quach T, Molinski T. Oxazoline-oxazinone oxidative rearrangement. divergent syntheses of (2S,3S)-4,4,4-trifluorovaline and (2S,4S)-5,5,5-Trifluoroleucine. J Org Chem. 2009 Aug 07; 74(15):5510-5. PMID: 19537688.
      View in: PubMed
    55. Dalisay DS, Morinaka BI, Skepper CK, Molinski T. A tetrachloro polyketide hexahydro-1H-isoindolone, muironolide A, from the marine sponge Phorbas sp. natural products at the nanomole scale. J Am Chem Soc. 2009 Jun 10; 131(22):7552-3. PMID: 19453148.
      View in: PubMed
    56. Molinski T. Marine natural products. Clin Adv Hematol Oncol. 2009 Jun; 7(6):383-5. PMID: 19606073.
      View in: PubMed
    57. Dalisay DS, Molinski T. Structure elucidation at the nanomole scale. 2. Hemi-phorboxazole A from Phorbas sp. Org Lett. 2009 May 07; 11(9):1967-70. PMID: 19341267.
      View in: PubMed
    58. Mulder RJ, Shafer CM, Dalisay DS, Molinski T. Synthesis and structure-activity relationships of bengazole A analogs. Bioorg Med Chem Lett. 2009 Jun 01; 19(11):2928-30. PMID: 19419860; PMCID: PMC2691865.
    59. Dalisay DS, Molinski T. NMR quantitation of natural products at the nanomole scale. J Nat Prod. 2009 Apr; 72(4):739-44. PMID: 19399996; PMCID: PMC2753506.
    60. Dalisay DS, Rogers EW, Edison AS, Molinski T. Structure elucidation at the nanomole scale. 1. Trisoxazole macrolides and thiazole-containing cyclic peptides from the nudibranch Hexabranchus sanguineus. J Nat Prod. 2009 Apr; 72(4):732-8. PMID: 19254038; PMCID: PMC2753413.
    61. Dalisay DS, Tsukamoto S, Molinski T. Absolute configuration of the alpha,omega-bifunctionalized sphingolipid leucettamol A from Leucetta microrhaphis by deconvoluted exciton coupled CD. J Nat Prod. 2009 Mar 27; 72(3):353-9. PMID: 19159253; PMCID: PMC2765480.
    62. Molinski T. Nanomole-scale natural products discovery. Curr Opin Drug Discov Devel. 2009 Mar; 12(2):197-206. PMID: 19333865.
      View in: PubMed
    63. Morinaka BI, Pawlik JR, Molinski T. Amaroxocanes A and B: sulfated dimeric sterols defend the Caribbean coral reef sponge Phorbas amaranthus from fish predators. J Nat Prod. 2009 Feb 27; 72(2):259-64. PMID: 19143510.
      View in: PubMed
    64. Dalisay DS, Quach T, Nicholas GN, Molinski T. Amplification of the Cotton effect of a single chromophore through liposomal ordering-stereochemical assignment of plakinic acids I and J. Angew Chem Int Ed Engl. 2009; 48(24):4367-71. PMID: 19437515; PMCID: PMC2872062.
    65. Molinski T, Dalisay DS, Lievens SL, Saludes JP. Drug development from marine natural products. Nat Rev Drug Discov. 2009 Jan; 8(1):69-85. PMID: 19096380.
      View in: PubMed
    66. Skepper CK, Dalisay DS, Molinski T. Synthesis and antifungal activity of (-)-(Z)-dysidazirine. Org Lett. 2008 Nov 20; 10(22):5269-71. PMID: 18937483; PMCID: PMC2635126.
    67. Morinaka BI, Molinski T. Exciton coupling circular dichroism of an allylic N-imidazolyl group in amaranzole A, a marine natural product from Phorbas amaranthus. Chirality. 2008 Sep; 20(9):1066-70. PMID: 18690668; PMCID: PMC2615005.
    68. MacMillan JB, Xiong-Zhou G, Skepper CK, Molinski T. Phorbasides A-E, cytotoxic chlorocyclopropane macrolide glycosides from the marine sponge Phorbas sp. CD determination of C-methyl sugar configurations. J Org Chem. 2008 May 16; 73(10):3699-706. PMID: 18412387.
      View in: PubMed
    69. Skepper CK, Molinski T. Long-chain 2H-azirines with heterogeneous terminal halogenation from the marine sponge Dysidea fragilis. J Org Chem. 2008 Apr 04; 73(7):2592-7. PMID: 18321120.
      View in: PubMed
    70. Dadsetan S, Zakharova L, Molinski T, Fomina AF. Store-operated Ca2+ influx causes Ca2+ release from the intracellular Ca2+ channels that is required for T cell activation. J Biol Chem. 2008 May 02; 283(18):12512-9. PMID: 18316371.
      View in: PubMed
    71. Rogers EW, Dalisay DS, Molinski T. (+)-Zwittermicin A: assignment of its complete configuration by total synthesis of the enantiomer and implication of D-serine in its biosynthesis. Angew Chem Int Ed Engl. 2008; 47(42):8086-9. PMID: 18798190; PMCID: PMC3957322.
    72. Makarieva TN, Dmitrenok PS, Zakharenko AM, Denisenko VA, Guzii AG, Li R, Skepper CK, Molinski T, Stonik VA. Rhizochalins C and D from the sponge Rhizochalina incrustata. A rare threo-sphingolipid and a facile method for determination of the carbonyl position in alpha,omega-bifunctionalized ketosphingolipids. J Nat Prod. 2007 Dec; 70(12):1991-8. PMID: 18052325.
      View in: PubMed
    73. Schuetz A, Junker J, Leonov A, Lange OF, Molinski T, Griesinger C. Stereochemistry of sagittamide A from residual dipolar coupling enhanced NMR. J Am Chem Soc. 2007 Dec 12; 129(49):15114-5. PMID: 17999506.
      View in: PubMed
    74. Morinaka BI, Masuno MN, Pawlik JR, Molinski T. Amaranzole A, a new N-imidazolyl steroid from Phorbas amaranthus. Org Lett. 2007 Dec 06; 9(25):5219-22. PMID: 17990891.
      View in: PubMed
    75. Rogers EW, Molinski T. Highly polar spiroisoxazolines from the sponge Aplysina fulva. J Nat Prod. 2007 Jul; 70(7):1191-4. PMID: 17579462; PMCID: PMC2533261.
    76. Morinaka BI, Skepper CK, Molinski T. Ene-yne tetrahydrofurans from the sponge Xestospongia muta. exploiting a weak CD effect for assignment of configuration. Org Lett. 2007 May 10; 9(10):1975-8. PMID: 17439137.
      View in: PubMed
    77. Skepper CK, Macmillan JB, Zhou GX, Masuno MN, Molinski T. Chlorocyclopropane macrolides from the marine sponge Phorbas sp. assignment of the configurations of phorbasides A and B by quantitative CD. J Am Chem Soc. 2007 Apr 11; 129(14):4150-1. PMID: 17373800.
      View in: PubMed
    78. Saludes JP, Lievens SC, Molinski T. Occurrence of the alpha-glucosidase inhibitor 1,4-Dideoxy-1,4-imino-D-arabinitol and related iminopentitols in marine sponges. J Nat Prod. 2007 Mar; 70(3):436-8. PMID: 17378534.
      View in: PubMed
    79. Rogers EW, Molinski T. Asymmetric synthesis of diastereomeric diaminoheptanetetraols. A proposal for the configuration of (+)-zwittermicin a. Org Lett. 2007 Feb 01; 9(3):437-40. PMID: 17249781; PMCID: PMC2729442.
    80. Yang T, Esteve E, Pessah IN, Molinski T, Allen PD, López JR. Elevated resting [Ca(2+)](i) in myotubes expressing malignant hyperthermia RyR1 cDNAs is partially restored by modulation of passive calcium leak from the SR. Am J Physiol Cell Physiol. 2007 May; 292(5):C1591-8. PMID: 17182726.
      View in: PubMed
    81. Lievens SC, Molinski T. Progressive-convergent elucidation of stereochemistry in complex polyols. The absolute configuration of (-)-sagittamide A. J Am Chem Soc. 2006 Sep 13; 128(36):11764-5. PMID: 16953609; PMCID: PMC3340292.
    82. Masuno MN, Pessah IN, Olmstead MM, Molinski T. Simplified cyclic analogues of bastadin-5. Structure-activity relationships for modulation of the RyR1/FKBP12 Ca2+ channel complex. J Med Chem. 2006 Jul 27; 49(15):4497-511. PMID: 16854055; PMCID: PMC3987770.
    83. Linington RG, Robertson M, Gauthier A, Finlay BB, MacMillan JB, Molinski T, van Soest R, Andersen RJ. Caminosides B-D, antimicrobial glycolipids isolated from the marine sponge Caminus sphaeroconia. J Nat Prod. 2006 Feb; 69(2):173-7. PMID: 16499312.
      View in: PubMed
    84. Zhou GX, Molinski T. Manoalide derivatives from a sponge, Luffariella sp. J Asian Nat Prod Res. 2006 Jan-Mar; 8(1-2):15-20. PMID: 16753777.
      View in: PubMed
    85. Ta TA, Feng W, Molinski T, Pessah IN. Hydroxylated xestospongins block inositol-1,4,5-trisphosphate-induced Ca2+ release and sensitize Ca2+-induced Ca2+ release mediated by ryanodine receptors. Mol Pharmacol. 2006 Feb; 69(2):532-8. PMID: 16249374.
      View in: PubMed
    86. Makarieva TN, Denisenko VA, Dmitrenok PS, Guzii AG, Santalova EA, Stonik VA, Macmillan JB, Molinski T. Oceanalin A, a hybrid alpha,omega-bifunctionalized sphingoid tetrahydroisoquinoline beta-glycoside from the marine sponge Oceanapia sp. Org Lett. 2005 Jul 07; 7(14):2897-900. PMID: 15987164.
      View in: PubMed
    87. Rogers EW, de Oliveira MF, Berlinck RG, König GM, Molinski T. Stereochemical heterogeneity in Verongid sponge metabolites. Absolute stereochemistry of (+)-fistularin-3 and (+)-11-epi-fistularin-3 by microscale LCMS-Marfey's analysis. J Nat Prod. 2005 Jun; 68(6):891-6. PMID: 15974614.
      View in: PubMed
    88. Lievens SC, Molinski T. Sagittamides A and B. Polyacetoxy long-chain acyl amino acids from a didemnid ascidian. Org Lett. 2005 May 26; 7(11):2281-4. PMID: 15901189.
      View in: PubMed
    89. Masuno MN, Young DM, Hoepker AC, Skepper CK, Molinski T. Addition of Cl2C: to (-)-O-menthyl acrylate under sonication-phase-transfer catalysis. Efficient synthesis of (+)- and (-)-(2-chlorocyclopropyl)methanol. J Org Chem. 2005 May 13; 70(10):4162-5. PMID: 15876110.
      View in: PubMed
    90. Macmillan JB, Molinski T. Majusculoic acid, a brominated cyclopropyl fatty acid from a marine cyanobacterial mat assemblage. J Nat Prod. 2005 Apr; 68(4):604-6. PMID: 15844960.
      View in: PubMed
    91. Rogers EW, Molinski T. A cytotoxic carotenoid from the marine sponge Prianos osiros. J Nat Prod. 2005 Mar; 68(3):450-2. PMID: 15787458.
      View in: PubMed
    92. Makarieva TN, Guzii AG, Denisenko VA, Dmitrenok PS, Santalova EA, Pokanevich EV, Molinski T, Stonik VA. Rhizochalin A, a novel two-headed sphingolipid from the sponge Rhizochalina incrustata. J Nat Prod. 2005 Feb; 68(2):255-7. PMID: 15730256.
      View in: PubMed
    93. Grubb CD, Zipp BJ, Ludwig-Müller J, Masuno MN, Molinski T, Abel S. Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis. Plant J. 2004 Dec; 40(6):893-908. PMID: 15584955.
      View in: PubMed
    94. Lievens SC, Hope H, Molinski T. New 3-oxo-chol-4-en-24-oic acids from the marine soft coral Eleutherobia sp. J Nat Prod. 2004 Dec; 67(12):2130-2. PMID: 15620271.
      View in: PubMed
    95. Macmillan JB, Linington RG, Andersen RJ, Molinski T. Stereochemical assignment in acyclic lipids across long distance by circular dichroism: absolute stereochemistry of the aglycone of caminoside A. Angew Chem Int Ed Engl. 2004 Nov 12; 43(44):5946-51. PMID: 15547902.
      View in: PubMed
    96. Liu C, Masuno MN, Macmillan JB, Molinski T. Enantioselective total synthesis of (+)-milnamide A and evidence of its autoxidation to (+)-milnamide D. Angew Chem Int Ed Engl. 2004 Nov 12; 43(44):5951-4. PMID: 15547903.
      View in: PubMed
    97. Kossuga MH, MacMillan JB, Rogers EW, Molinski T, Nascimento GG, Rocha RM, Berlinck RG. (2S,3R)-2-aminododecan-3-ol, a new antifungal agent from the ascidian Clavelina oblonga. J Nat Prod. 2004 Nov; 67(11):1879-81. PMID: 15568780.
      View in: PubMed
    98. MacMillan JB, Molinski T. Long-range stereo-relay: relative and absolute configuration of 1,n-glycols from circular dichroism of liposomal porphyrin esters. J Am Chem Soc. 2004 Aug 18; 126(32):9944-5. PMID: 15303868.
      View in: PubMed
    99. Andersen RJ, Ireland CM, Molinski T, Bewley CA. Research achievement award--D. John Faulkner. J Nat Prod. 2004 Aug; 67(8):1239-51. PMID: 15332836.
      View in: PubMed
    100. Masuno MN, Pawlik JR, Molinski T. Phorbasterones A-D, cytotoxic nor-ring A steroids from the sponge Phorbas amaranthus. J Nat Prod. 2004 Apr; 67(4):731-3. PMID: 15104518.
      View in: PubMed
    101. Richter RK, Mickus DE, Rychnovsky SD, Molinski T. Differential modulation of the antifungal activity of amphotericin B by natural and ent-cholesterol. Bioorg Med Chem Lett. 2004 Jan 05; 14(1):115-8. PMID: 14684310.
      View in: PubMed
    102. Masuno MN, Molinski T. Cationic reduction of bastadin-4 to bastadin-5. Preparation of 5-[2h]-bastadin-5 by site-specific isotopic labeling. J Nat Prod. 2003 Jan; 66(1):112-4. PMID: 12542356.
      View in: PubMed
    103. MacMillan JB, Ernst-Russell MA, de Ropp JS, Molinski T. Lobocyclamides A-C, lipopeptides from a cryptic cyanobacterial mat containing Lyngbya confervoides. J Org Chem. 2002 Nov 15; 67(23):8210-5. PMID: 12423153.
      View in: PubMed
    104. Nicholas GM, Li R, MacMillan JB, Molinski T. Antifungal activity of bifunctional sphingolipids. Intramolecular synergism within long-chain alpha,omega-bis-aminoalcohols. Bioorg Med Chem Lett. 2002 Aug 19; 12(16):2159-62. PMID: 12127527.
      View in: PubMed
    105. MacMillan JB, Molinski T. Lobocyclamide B from Lyngbya confervoides. Configuration and asymmetric synthesis of beta-hydroxy-alpha-amino acids by (-)-sparteine-mediated aldol addition. Org Lett. 2002 May 30; 4(11):1883-6. PMID: 12027638.
      View in: PubMed
    106. MacMillan JB, Molinski T. Caylobolide A, a unique 36-membered macrolactone from a Bahamian Lyngbya majuscula. Org Lett. 2002 May 02; 4(9):1535-8. PMID: 11975622.
      View in: PubMed
    107. Moon SS, MacMillan JB, Olmstead MM, Ta TA, Pessah IN, Molinski T. (+)-7S-Hydroxyxestospongin A from the marine sponge Xestospongia sp. and absolute configuration of (+)-xestospongin D. J Nat Prod. 2002 Mar; 65(3):249-54. PMID: 11908959.
      View in: PubMed
    108. Mulder RJ, Shafer CM, Molinski T. First Total Synthesis of Bengazole A. J Org Chem. 1999 Jun 25; 64(13):4995-4998. PMID: 11674590.
      View in: PubMed
    109. Shafer CM, Molinski T. Monosubstituted Oxazoles. 1. Synthesis of 5-Substituted Oxazoles by Directed Alkylation. J Org Chem. 1998 Feb 06; 63(3):551-555. PMID: 11672044.
      View in: PubMed
    110. Searle PA, Richter RK, Molinski T. Bengazoles C-G from the Sponge Jaspis sp. Synthesis of the Side Chain and Determination of Absolute Configuration. J Org Chem. 1996 Jun 14; 61(12):4073-4079. PMID: 11667285.
      View in: PubMed
    Tadeusz's Networks
    Concepts
    Derived automatically from this person's publications.
    _
    Co-Authors
    People in Profiles who have published with this person.
    _
    Related Authors
    People who share related concepts with this person.
    _