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Pathobiont-driven antibody sialylation through IL-10 undermines vaccination. J Clin Invest. 2024 Dec 16; 134(24).
Tsai CM, Hajam IA, Caldera JR, Chiang AW, Gonzalez C, Du X, Choudhruy B, Li H, Suzuki E, Askarian F, Clark T, Lin B, Wierzbicki IH, Riestra AM, Conrad DJ, Gonzalez DJ, Nizet V, Lewis NE, Liu GY. PMID: 39680460; PMCID: PMC11645145.
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PubMed Mentions: Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Comparison of Race-neutral Versus Race-specific Spirometry Equations for Evaluation of Child Asthma. Am J Respir Crit Care Med. 2024 Dec 06.
Non AL, Li X, Jones MR, Oken E, Hartert T, Schoettler N, Gold DR, Ramratnam S, Schauberger EM, Tantisira K, Bacharier LB, Conrad DJ, Carroll KN, Nkoy FL, Luttmann-Gibson H, Gilliland FD, Breton CV, Kattan M, Lemanske RF, Litonjua AA, McEvoy CT, Rivera-Spoljaric K, Rosas-Salazar C, Joseph CLM, Palmore M, Ryan PH, Wegienka G, Sitarik AR, Singh AM, Miller RL, Zoratti EM, Ownby D, Camargo CA, Aschner JL, Stroustrup A, Farzan SF, Karagas MR, Jackson DJ, Gern JE, ECHO Cohort Consortium. PMID: 39642347.
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PubMed Mentions: Fields:
-
A GMR enzymatic assay for quantifying nuclease and peptidase activity. Front Bioeng Biotechnol. 2024; 12:1363186.
Sveiven M, Serrano AK, Rosenberg J, Conrad DJ, Hall DA, O'Donoghue AJ. PMID: 38544982; PMCID: PMC10966768.
View in:
PubMed Mentions:
1
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Early Evidence of Chronic Obstructive Pulmonary Disease Obscured by Race-Specific Prediction Equations. Am J Respir Crit Care Med. 2024 01 01; 209(1):59-69.
Regan EA, Lowe ME, Make BJ, Curtis JL, Chen QG, Crooks JL, Wilson C, Oates GR, Gregg RW, Baldomero AK, Bhatt SP, Diaz AA, Benos PV, O'Brien JK, Young KA, Kinney GL, Conrad DJ, Lowe KE, DeMeo DL, Non A, Cho MH, Kallet J, Foreman MG, Westney GE, Hoth K, MacIntyre NR, Hanania NA, Wolfe A, Amaza H, Han M, Beaty TH, Hansel NN, McCormack MC, Balasubramanian A, Crapo JD, Silverman EK, Casaburi R, Wise RA. PMID: 37611073; PMCID: PMC10870894.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Compounding Achromobacter Phages for Therapeutic Applications. Viruses. 2023 07 30; 15(8).
Cobián Güemes AG, Le T, Rojas MI, Jacobson NE, Villela H, McNair K, Hung SH, Han L, Boling L, Octavio JC, Dominguez L, Cantú VA, Archdeacon S, Vega AA, An MA, Hajama H, Burkeen G, Edwards RA, Conrad DJ, Rohwer F, Segall AM. PMID: 37632008; PMCID: PMC10457797.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Race-Specific Spirometry Equations Do Not Improve Models of Dyspnea and Quantitative Chest CT Phenotypes. Chest. 2023 12; 164(6):1492-1504.
Non AL, Bailey B, Bhatt SP, Casaburi R, Regan EA, Wang A, Limon A, Rabay C, Diaz AA, Baldomero AK, Kinney G, Young KA, Felts B, Hand C, Conrad DJ. PMID: 37507005; PMCID: PMC10925545.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia. Proc Natl Acad Sci U S A. 2023 07 25; 120(30):e2301538120.
Askarian F, Tsai CM, Cordara G, Zurich RH, Bjånes E, Golten O, Vinther Sørensen H, Kousha A, Meier A, Chikwati E, Bruun JA, Ludviksen JA, Choudhury B, Trieu D, Davis S, Edvardsen PKT, Mollnes TE, Liu GY, Krengel U, Conrad DJ, Vaaje-Kolstad G, Nizet V. PMID: 37459522; PMCID: PMC10372616.
View in:
PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Bacteriophage Therapy of Multidrug-resistant Achromobacter in an 11-Year-old Boy With Cystic Fibrosis Assessed by Metagenome Analysis. Pediatr Infect Dis J. 2023 09 01; 42(9):754-759.
Bradley JS, Hajama H, Akong K, Jordan M, Stout D, Rowe RS, Conrad DJ, Hingtgen S, Segall AM. PMID: 37343220.
View in:
PubMed Mentions:
5 Fields:
Translation:
HumansCells
-
Is it time to end race and ethnicity adjustment for pediatric pulmonary function tests? Pediatr Pulmonol. 2024 Dec; 59(12):3806-3811.
Non AL, Akong K, Conrad DJ. PMID: 37132943; PMCID: PMC11601010.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
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Use of the Spirometric "Fixed-Ratio" Underdiagnoses COPD in African-Americans in a Longitudinal Cohort Study. J Gen Intern Med. 2023 10; 38(13):2988-2997.
Regan EA, Lowe ME, Make BJ, Curtis JL, Chen QG, Cho MH, Crooks JL, Lowe KE, Wilson C, O'Brien JK, Oates GR, Baldomero AK, Kinney GL, Young KA, Diaz AA, Bhatt SP, McCormack MC, Hansel NN, Kim V, Richmond NE, Westney GE, Foreman MG, Conrad DJ, DeMeo DL, Hoth KF, Amaza H, Balasubramanian A, Kallet J, Watts S, Hanania NA, Hokanson J, Beaty TH, Crapo JD, Silverman EK, Casaburi R, Wise R. PMID: 37072532; PMCID: PMC10593702.
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PubMed Mentions:
3 Fields:
Translation:
Humans
-
Cystic Fibrosis Screen Positive, Inconclusive Diagnosis Genotypes in People with Cystic Fibrosis from the U.S. Patient Registry. Ann Am Thorac Soc. 2023 04; 20(4):523-531.
Salinas DB, Wee CP, Bailey B, Raraigh K, Conrad D. PMID: 36409994; PMCID: PMC10112408.
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PubMed Mentions:
1 Fields:
Translation:
HumansPHPublic Health
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Safety and microbiological activity of phage therapy in persons with cystic fibrosis colonized with Pseudomonas aeruginosa: study protocol for a phase 1b/2, multicenter, randomized, double-blind, placebo-controlled trial. Trials. 2022 Dec 28; 23(1):1057.
Tamma PD, Souli M, Billard M, Campbell J, Conrad D, Ellison DW, Evans B, Evans SR, Greenwood-Quaintance KE, Filippov AA, Geres HS, Hamasaki T, Komarow L, Nikolich MP, Lodise TP, Nayak SU, Norice-Tra C, Patel R, Pride D, Russell J, Van Tyne D, Chambers HF, FowlerJr VG, Schooley RT, Antibacterial Resistance Leadership Group. PMID: 36578069; PMCID: PMC9795609.
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PubMed Mentions:
15 Fields:
Translation:
HumansCellsCTClinical Trials
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Unsupervised Learning Identifies Computed Tomographic Measurements as Primary Drivers of Progression, Exacerbation, and Mortality in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2022 12; 19(12):1993-2002.
Yuan NF, Hasenstab K, Retson T, Conrad DJ, Lynch DA, Hsiao A. PMID: 35830591.
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PubMed Mentions: Fields:
Translation:
Humans
-
Complex and unexpected outcomes of antibiotic therapy against a polymicrobial infection. ISME J. 2022 09; 16(9):2065-2075.
Ghuneim LJ, Raghuvanshi R, Neugebauer KA, Guzior DV, Christian MH, Schena B, Feiner JM, Castillo-Bahena A, Mielke J, McClelland M, Conrad D, Klapper I, Zhang T, Quinn RA. PMID: 35597889; PMCID: PMC9381758.
View in:
PubMed Mentions:
10 Fields:
Translation:
Humans
-
Stenotrophomonas maltophilia in patients with bronchiectasis: An analysis of the US bronchiectasis and NTM Research Registry. Respir Med. 2022 03; 193:106746.
Metersky ML, Choate R, Aksamit TR, Conrad D, Lapinel NC, Maselli DJ, McShane PJ. PMID: 35124355.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
-
Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice. J Immunol. 2022 02 01; 208(3):745-752.
Fan Z, Pitmon E, Wen L, Miller J, Ehinger E, Herro R, Liu W, Chen J, Mikulski Z, Conrad DJ, Marki A, Orecchioni M, Kumari P, Zhu YP, Marcovecchio PM, Hedrick CC, Hodges CA, Rathinam VA, Wang K, Ley K. PMID: 35031577; PMCID: PMC8855460.
View in:
PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
-
Erratum: Automated CT Staging of Chronic Obstructive Pulmonary Disease Severity for Predicting Disease Progression and Mortality with a Deep Learning Convolutional Neural Network. Radiol Cardiothorac Imaging. 2022 Feb; 4(1):e219002.
Hasenstab KA, Yuan N, Retson T, Conrad DJ, Kligerman S, Lynch DA, Hsiao A, COPDGene Investigators. PMID: 35782763; PMCID: PMC8893205.
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PubMed Mentions: Fields:
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Multi-Omics Study of Keystone Species in a Cystic Fibrosis Microbiome. Int J Mol Sci. 2021 Nov 07; 22(21).
Silveira CB, Cobián-Güemes AG, Uranga C, Baker JL, Edlund A, Rohwer F, Conrad D. PMID: 34769481; PMCID: PMC8584531.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
Draft Genome Sequence of the Multidrug-Resistant Strain Pseudomonas aeruginosa PA291, Isolated from Cystic Fibrosis Sputum. Microbiol Resour Announc. 2021 Sep 09; 10(36):e0057221.
Luong T, Schumann A, Conrad D, Roach D. PMID: 34498926; PMCID: PMC8428245.
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PubMed Mentions:
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Plasmonic Sensing Studies of a Gas-Phase Cystic Fibrosis Marker in Moisture Laden Air. Sensors (Basel). 2021 May 29; 21(11).
Sun L, Conrad D, Hall DA, Benkstein KD, Semancik S, Zaghloul ME. PMID: 34072374; PMCID: PMC8197828.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Automated CT Staging of Chronic Obstructive Pulmonary Disease Severity for Predicting Disease Progression and Mortality with a Deep Learning Convolutional Neural Network. Radiol Cardiothorac Imaging. 2021 Apr; 3(2):e200477.
Hasenstab KA, Yuan N, Retson T, Conrad DJ, Kligerman S, Lynch DA, Hsiao A, COPDGene Investigators. PMID: 33969307; PMCID: PMC8098086.
View in:
PubMed Mentions:
17 Fields:
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Multi-dimensional clinical phenotyping of a national cohort of adult cystic fibrosis patients. J Cyst Fibros. 2021 01; 20(1):91-96.
Conrad DJ, Billings J, Teneback C, Koff J, Rosenbluth D, Bailey BA, Jain R. PMID: 32948498.
View in:
PubMed Mentions:
5 Fields:
Translation:
Humans
-
High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic Therapy. mSystems. 2020 Jun 23; 5(3).
Raghuvanshi R, Vasco K, Vázquez-Baeza Y, Jiang L, Morton JT, Li D, Gonzalez A, DeRight Goldasich L, Humphrey G, Ackermann G, Swafford AD, Conrad D, Knight R, Dorrestein PC, Quinn RA. PMID: 32576651; PMCID: PMC7311317.
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PubMed Mentions:
42 Fields:
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Safety, Tolerability, and Effects of Sodium Bicarbonate Inhalation in Cystic Fibrosis. Clin Drug Investig. 2020 Feb; 40(2):105-117.
Gomez CCS, Parazzi PLF, Clinckspoor KJ, Mauch RM, Pessine FBT, Levy CE, Peixoto AO, Ribeiro MÂGO, Ribeiro AF, Conrad D, Quinton PM, Marson FAL, Ribeiro JD. PMID: 31721070.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
COPDGene® 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease. Chronic Obstr Pulm Dis. 2019 Nov; 6(5):384-399.
Lowe KE, Regan EA, Anzueto A, Austin E, Austin JHM, Beaty TH, Benos PV, Benway CJ, Bhatt SP, Bleecker ER, Bodduluri S, Bon J, Boriek AM, Boueiz AR, Bowler RP, Budoff M, Casaburi R, Castaldi PJ, Charbonnier JP, Cho MH, Comellas A, Conrad D, Costa Davis C, Criner GJ, Curran-Everett D, Curtis JL, DeMeo DL, Diaz AA, Dransfield MT, Dy JG, Fawzy A, Fleming M, Flenaugh EL, Foreman MG, Fortis S, Gebrekristos H, Grant S, Grenier PA, Gu T, Gupta A, Han MK, Hanania NA, Hansel NN, Hayden LP, Hersh CP, Hobbs BD, Hoffman EA, Hogg JC, Hokanson JE, Hoth KF, Hsiao A, Humphries S, Jacobs K, Jacobson FL, Kazerooni EA, Kim V, Kim WJ, Kinney GL, Koegler H, Lutz SM, Lynch DA, MacIntye NR, Make BJ, Marchetti N, Martinez FJ, Maselli DJ, Mathews AM, McCormack MC, McDonald MN, McEvoy CE, Moll M, Molye SS, Murray S, Nath H, Newell JD, Occhipinti M, Paoletti M, Parekh T, Pistolesi M, Pratte KA, Putcha N, Ragland M, Reinhardt JM, Rennard SI, Rosiello RA, Ross JC, Rossiter HB, Ruczinski I, San Jose Estepar R, Sciurba FC, Sieren JC, Singh H, Soler X, Steiner RM, Strand MJ, Stringer WW, Tal-Singer R, Thomashow B, Vegas Sánchez-Ferrero G, Walsh JW, Wan ES, Washko GR, Michael Wells J, Wendt CH, Westney G, Wilson A, Wise RA, Yen A, Young K, Yun J, Silverman EK, Crapo JD. PMID: 31710793; PMCID: PMC7020846.
View in:
PubMed Mentions:
91
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Optimizing sequencing protocols for leaderboard metagenomics by combining long and short reads. Genome Biol. 2019 10 31; 20(1):226.
Sanders JG, Nurk S, Salido RA, Minich J, Xu ZZ, Zhu Q, Martino C, Fedarko M, Arthur TD, Chen F, Boland BS, Humphrey GC, Brennan C, Sanders K, Gaffney J, Jepsen K, Khosroheidari M, Green C, Liyanage M, Dang JW, Phelan VV, Quinn RA, Bankevich A, Chang JT, Rana TM, Conrad DJ, Sandborn WJ, Smarr L, Dorrestein PC, Pevzner PA, Knight R. PMID: 31672156; PMCID: PMC6822431.
View in:
PubMed Mentions:
30 Fields:
Translation:
HumansAnimals
-
Molecular and Microbial Microenvironments in Chronically Diseased Lungs Associated with Cystic Fibrosis. mSystems. 2019 Sep 24; 4(5).
Melnik AV, Vázquez-Baeza Y, Aksenov AA, Hyde E, McAvoy AC, Wang M, da Silva RR, Protsyuk I, Wu JV, Bouslimani A, Lim YW, Luzzatto-Knaan T, Comstock W, Quinn RA, Wong R, Humphrey G, Ackermann G, Spivey T, Brouha SS, Bandeira N, Lin GY, Rohwer F, Conrad DJ, Alexandrov T, Knight R, Dorrestein PC, Garg N. PMID: 31551401; PMCID: PMC6759567.
View in:
PubMed Mentions:
18 Fields:
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Cystic Fibrosis Rapid Response: Translating Multi-omics Data into Clinically Relevant Information. mBio. 2019 04 16; 10(2).
Cobián Güemes AG, Lim YW, Quinn RA, Conrad DJ, Benler S, Maughan H, Edwards R, Brettin T, Cantú VA, Cuevas D, Hamidi R, Dorrestein P, Rohwer F. PMID: 30992350; PMCID: PMC6469968.
View in:
PubMed Mentions:
16 Fields:
Translation:
HumansCells
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Niche partitioning of a pathogenic microbiome driven by chemical gradients. Sci Adv. 2018 09; 4(9):eaau1908.
Quinn RA, Comstock W, Zhang T, Morton JT, da Silva R, Tran A, Aksenov A, Nothias LF, Wangpraseurt D, Melnik AV, Ackermann G, Conrad D, Klapper I, Knight R, Dorrestein PC. PMID: 30263961; PMCID: PMC6157970.
View in:
PubMed Mentions:
29 Fields:
Translation:
HumansCells
-
Median regression spline modeling of longitudinal FEV1 measurements in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients. PLoS One. 2017; 12(12):e0190061.
Conrad DJ, Bailey BA, Hardie JA, Bakke PS, Eagan TML, Aarli BB. PMID: 29261779; PMCID: PMC5738083.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Three-Dimensional Microbiome and Metabolome Cartography of a Diseased Human Lung. Cell Host Microbe. 2017 Nov 08; 22(5):705-716.e4.
Garg N, Wang M, Hyde E, da Silva RR, Melnik AV, Protsyuk I, Bouslimani A, Lim YW, Wong R, Humphrey G, Ackermann G, Spivey T, Brouha SS, Bandeira N, Lin GY, Rohwer F, Conrad DJ, Alexandrov T, Knight R, Dorrestein PC. PMID: 29056429; PMCID: PMC6267898.
View in:
PubMed Mentions:
66 Fields:
Translation:
HumansCells
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Smartphone-Based pH Sensor for Home Monitoring of Pulmonary Exacerbations in Cystic Fibrosis. Sensors (Basel). 2017 May 30; 17(6).
Sun A, Phelps T, Yao C, Venkatesh AG, Conrad D, Hall DA. PMID: 28556804; PMCID: PMC5491989.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Ecological networking of cystic fibrosis lung infections. NPJ Biofilms Microbiomes. 2016; 2:4.
Quinn RA, Whiteson K, Lim YW, Zhao J, Conrad D, LiPuma JJ, Rohwer F, Widder S. PMID: 28649398; PMCID: PMC5460249.
View in:
PubMed Mentions:
50 Fields:
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Metabolomics of pulmonary exacerbations reveals the personalized nature of cystic fibrosis disease. PeerJ. 2016; 4:e2174.
Quinn RA, Lim YW, Mak TD, Whiteson K, Furlan M, Conrad D, Rohwer F, Dorrestein P. PMID: 27602256; PMCID: PMC4991883.
View in:
PubMed Mentions:
24 Fields:
-
Longitudinal Metagenomic Analysis of Hospital Air Identifies Clinically Relevant Microbes. PLoS One. 2016; 11(8):e0160124.
King P, Pham LK, Waltz S, Sphar D, Yamamoto RT, Conrad D, Taplitz R, Torriani F, Forsyth RA. PMID: 27482891; PMCID: PMC4970769.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCellsPHPublic Health
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Characterizing Lung Disease in Cystic Fibrosis with Magnetic Resonance Imaging and Airway Physiology. PLoS One. 2016; 11(6):e0157177.
Theilmann RJ, Darquenne C, Elliott AR, Bailey BA, Conrad DJ. PMID: 27337056; PMCID: PMC4919047.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
A phase 3, multi-center, multinational, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of levofloxacin inhalation solution (APT-1026) in stable cystic fibrosis patients. J Cyst Fibros. 2016 07; 15(4):495-502.
Flume PA, VanDevanter DR, Morgan EE, Dudley MN, Loutit JS, Bell SC, Kerem E, Fischer R, Smyth AR, Aaron SD, Conrad D, Geller DE, Elborn JS. PMID: 26852040.
View in:
PubMed Mentions:
27 Fields:
Translation:
HumansCellsCTClinical Trials
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Using Cystic Fibrosis Therapies for Non-Cystic Fibrosis Bronchiectasis. Clin Chest Med. 2016 Mar; 37(1):139-46.
ElMaraachli W, Conrad DJ, Wang AC. PMID: 26857775.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Microbial, host and xenobiotic diversity in the cystic fibrosis sputum metabolome. ISME J. 2016 06; 10(6):1483-98.
Quinn RA, Phelan VV, Whiteson KL, Garg N, Bailey BA, Lim YW, Conrad DJ, Dorrestein PC, Rohwer FL. PMID: 26623545; PMCID: PMC5029181.
View in:
PubMed Mentions:
55 Fields:
Translation:
HumansCells
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Multidimensional clinical phenotyping of an adult cystic fibrosis patient population. PLoS One. 2015; 10(3):e0122705.
Conrad DJ, Bailey BA. PMID: 25822311; PMCID: PMC4378917.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
Mass spectral similarity for untargeted metabolomics data analysis of complex mixtures. Int J Mass Spectrom. 2015 Feb 01; 377:719-717.
Garg N, Kapono C, Lim YW, Koyama N, Vermeij MJ, Conrad D, Rohwer F, Dorrestein PC. PMID: 25844058; PMCID: PMC4379709.
View in:
PubMed Mentions:
46
-
A phase 3, open-label, randomized trial to evaluate the safety and efficacy of levofloxacin inhalation solution (APT-1026) versus tobramycin inhalation solution in stable cystic fibrosis patients. J Cyst Fibros. 2015 Jul; 14(4):507-14.
Stuart Elborn J, Geller DE, Conrad D, Aaron SD, Smyth AR, Fischer R, Kerem E, Bell SC, Loutit JS, Dudley MN, Morgan EE, VanDevanter DR, Flume PA. PMID: 25592656.
View in:
PubMed Mentions:
32 Fields:
Translation:
HumansCellsCTClinical Trials
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The upper respiratory tract as a microbial source for pulmonary infections in cystic fibrosis. Parallels from island biogeography. Am J Respir Crit Care Med. 2014 Jun 01; 189(11):1309-15.
Whiteson KL, Bailey B, Bergkessel M, Conrad D, Delhaes L, Felts B, Harris JK, Hunter R, Lim YW, Maughan H, Quinn R, Salamon P, Sullivan J, Wagner BD, Rainey PB. PMID: 24702670; PMCID: PMC4098084.
View in:
PubMed Mentions:
58 Fields:
Translation:
Humans
-
Biogeochemical forces shape the composition and physiology of polymicrobial communities in the cystic fibrosis lung. mBio. 2014 Mar 18; 5(2):e00956-13.
Quinn RA, Lim YW, Maughan H, Conrad D, Rohwer F, Whiteson KL. PMID: 24643867; PMCID: PMC3967525.
View in:
PubMed Mentions:
68 Fields:
Translation:
HumansCells
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Breath gas metabolites and bacterial metagenomes from cystic fibrosis airways indicate active pH neutral 2,3-butanedione fermentation. ISME J. 2014 Jun; 8(6):1247-58.
Whiteson KL, Meinardi S, Lim YW, Schmieder R, Maughan H, Quinn R, Blake DR, Conrad D, Rohwer F. PMID: 24401860; PMCID: PMC4030226.
View in:
PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Clinical insights from metagenomic analysis of sputum samples from patients with cystic fibrosis. J Clin Microbiol. 2014 Feb; 52(2):425-37.
Lim YW, Evangelista JS, Schmieder R, Bailey B, Haynes M, Furlan M, Maughan H, Edwards R, Rohwer F, Conrad D. PMID: 24478471; PMCID: PMC3911355.
View in:
PubMed Mentions:
80 Fields:
Translation:
HumansAnimalsCells
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Mechanistic model of Rothia mucilaginosa adaptation toward persistence in the CF lung, based on a genome reconstructed from metagenomic data. PLoS One. 2013; 8(5):e64285.
Lim YW, Schmieder R, Haynes M, Furlan M, Matthews TD, Whiteson K, Poole SJ, Hayes CS, Low DA, Maughan H, Edwards R, Conrad D, Rohwer F. PMID: 23737977; PMCID: PMC3667864.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
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Toward implementation of quorum sensing autoinducers as biomarkers for infectious disease states. Anal Chem. 2013 Mar 19; 85(6):3355-62.
Struss AK, Nunes A, Waalen J, Lowery CA, Pullanikat P, Denery JR, Conrad DJ, Kaufmann GF, Janda KD. PMID: 23391272; PMCID: PMC3604138.
View in:
PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Cystic fibrosis therapy: a community ecology perspective. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):150-6.
Conrad D, Haynes M, Salamon P, Rainey PB, Youle M, Rohwer F. PMID: 23103995; PMCID: PMC3604065.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCells
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Mucus distribution model in a lung with cystic fibrosis. Comput Math Methods Med. 2012; 2012:970809.
Zarei S, Mirtar A, Rohwer F, Conrad DJ, Theilmann RJ, Salamon P. PMID: 23118803; PMCID: PMC3483681.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Metagenomics and metatranscriptomics: windows on CF-associated viral and microbial communities. J Cyst Fibros. 2013 Mar; 12(2):154-64.
Lim YW, Schmieder R, Haynes M, Willner D, Furlan M, Youle M, Abbott K, Edwards R, Evangelista J, Conrad D, Rohwer F. PMID: 22951208; PMCID: PMC3534838.
View in:
PubMed Mentions:
92 Fields:
Translation:
HumansCells
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β-adrenergic sweat secretion as a diagnostic test for cystic fibrosis. Am J Respir Crit Care Med. 2012 Oct 15; 186(8):732-9.
Quinton P, Molyneux L, Ip W, Dupuis A, Avolio J, Tullis E, Conrad D, Shamsuddin AK, Durie P, Gonska T. PMID: 22859523.
View in:
PubMed Mentions:
36 Fields:
Translation:
Humans
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Case studies of the spatial heterogeneity of DNA viruses in the cystic fibrosis lung. Am J Respir Cell Mol Biol. 2012 Feb; 46(2):127-31.
Willner D, Haynes MR, Furlan M, Hanson N, Kirby B, Lim YW, Rainey PB, Schmieder R, Youle M, Conrad D, Rohwer F. PMID: 21980056; PMCID: PMC3361360.
View in:
PubMed Mentions:
58 Fields:
Translation:
HumansCells
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Spatial distribution of microbial communities in the cystic fibrosis lung. ISME J. 2012 Feb; 6(2):471-4.
Willner D, Haynes MR, Furlan M, Schmieder R, Lim YW, Rainey PB, Rohwer F, Conrad D. PMID: 21796216; PMCID: PMC3260497.
View in:
PubMed Mentions:
103 Fields:
Translation:
Humans
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Levofloxacin inhalation solution (MP-376) in patients with cystic fibrosis with Pseudomonas aeruginosa. Am J Respir Crit Care Med. 2011 Jun 01; 183(11):1510-6.
Geller DE, Flume PA, Staab D, Fischer R, Loutit JS, Conrad DJ, Mpex 204 Study Group. PMID: 21471106.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
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HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression. J Inflamm (Lond). 2010 Oct 30; 7:52.
Conrad D, Wang A, Pieters R, Nicoletti F, Mangano K, van Heeckeren AM, White SK, Frincke JM, Reading CL, Stickney D, Auci DL. PMID: 21034489; PMCID: PMC2984480.
View in:
PubMed Mentions:
5
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Novel components of the human metabolome: the identification, characterization and anti-inflammatory activity of two 5-androstene tetrols. Steroids. 2011 Jan; 76(1-2):145-55.
Ahlem CN, Page TM, Auci DL, Kennedy MR, Mangano K, Nicoletti F, Ge Y, Huang Y, White SK, Villegas S, Conrad D, Wang A, Reading CL, Frincke JM. PMID: 20974164.
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6 Fields:
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HumansAnimalsCells
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Metagenomic analysis of respiratory tract DNA viral communities in cystic fibrosis and non-cystic fibrosis individuals. PLoS One. 2009 Oct 09; 4(10):e7370.
Willner D, Furlan M, Haynes M, Schmieder R, Angly FE, Silva J, Tammadoni S, Nosrat B, Conrad D, Rohwer F. PMID: 19816605; PMCID: PMC2756586.
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217 Fields:
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Humans
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Frequency of mitochondrial 12S ribosomal RNA variants in an adult cystic fibrosis population. Pharmacogenet Genomics. 2008 Dec; 18(12):1095-102.
Conrad DJ, Stenbit AE, Zettner EM, Wick I, Eckhardt C, Hardiman G. PMID: 18830133.
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9 Fields:
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HumansCells
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Sleep disruption in cystic fibrosis. Med Hypotheses. 2008 Dec; 71(6):886-8.
Yue HJ, Conrad D, Dimsdale JE. PMID: 18835664.
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1 Fields:
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Humans
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Expression and activation of 15-lipoxygenase pathway in severe asthma: relationship to eosinophilic phenotype and collagen deposition. Clin Exp Allergy. 2002 Nov; 32(11):1558-65.
Chu HW, Balzar S, Westcott JY, Trudeau JB, Sun Y, Conrad DJ, Wenzel SE. PMID: 12569975.
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73 Fields:
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Peroxisome proliferator-activated receptor-gamma regulates airway epithelial cell activation. Am J Respir Cell Mol Biol. 2001 Jun; 24(6):688-93.
Wang AC, Dai X, Luu B, Conrad DJ. PMID: 11415933.
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43 Fields:
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HumansCells
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Regulation of human 12/15-lipoxygenase by Stat6-dependent transcription. Am J Respir Cell Mol Biol. 2000 Feb; 22(2):226-34.
Conrad DJ, Lu M. PMID: 10657944.
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21 Fields:
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HumansCells
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The arachidonate 12/15 lipoxygenases. A review of tissue expression and biologic function. Clin Rev Allergy Immunol. 1999 Spring-Summer; 17(1-2):71-89.
Conrad DJ. PMID: 10436860.
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33 Fields:
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HumansAnimals
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Recent advances in the understanding and treatment of cystic fibrosis. Curr Opin Pulm Med. 1998 May; 4(3):130-4.
Resnikoff JR, Conrad DJ. PMID: 9675514.
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1 Fields:
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Humans
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Characterization and sequence of an additional 15-lipoxygenase transcript and of the human gene. Biochim Biophys Acta. 1997 Jun 26; 1352(3):267-81.
Kritzik MR, Ziober AF, Dicharry S, Conrad DJ, Sigal E. PMID: 9224951.
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5 Fields:
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HumansCells
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15-lipoxygenase immunoreactivity in normal and in asthmatic airways. Am J Respir Crit Care Med. 1995 Apr; 151(4):1201-4.
Bradding P, Redington AE, Djukanovic R, Conrad DJ, Holgate ST. PMID: 7697253.
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18 Fields:
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HumansCells
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Human 15-lipoxygenase: a potential effector molecule for interleukin-4. Adv Prostaglandin Thromboxane Leukot Res. 1994; 22:309-16.
Sigal E, Conrad DJ. PMID: 7539577.
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3 Fields:
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HumansCells
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Human 15-lipoxygenase: induction by interleukin-4 and insights into positional specificity. J Lipid Mediat. 1993 Mar-Apr; 6(1-3):75-88.
Sigal E, Sloane DL, Conrad DJ. PMID: 8358018.
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5 Fields:
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HumansAnimalsCells
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Specific inflammatory cytokines regulate the expression of human monocyte 15-lipoxygenase. Proc Natl Acad Sci U S A. 1992 Jan 01; 89(1):217-21.
Conrad DJ, Kuhn H, Mulkins M, Highland E, Sigal E. PMID: 1729692; PMCID: PMC48207.
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106 Fields:
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Intravascular (angiotropic) large-cell lymphoma ('malignant angioendotheliomatosis') with small vessel pulmonary vascular obstruction and hypercalcemia. West J Med. 1991 Jul; 155(1):72-6.
Curtis JL, Warnock ML, Conrad DJ, Helfend LK, Boushey HA. PMID: 1877242; PMCID: PMC1002926.
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3 Fields:
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Humans
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Immunocytochemical localization of arachidonate 15-lipoxygenase in erythrocytes, leukocytes, and airway cells. J Clin Invest. 1991 Apr; 87(4):1139-45.
Nadel JA, Conrad DJ, Ueki IF, Schuster A, Sigal E. PMID: 2010530; PMCID: PMC295116.
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31 Fields:
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HumansAnimalsCells
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Arachidonate 15-lipoxygenase: immunocytochemical localization in blood and airway cells. Trans Assoc Am Physicians. 1990; 103:145-53.
Nadel JA, Ueki IF, Schuster A, Conrad DJ, Sigal E. PMID: 2132526.
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PubMed Mentions:
2 Fields:
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HumansAnimalsCells