Brent Aulston

Title(s)	Assistant Project Scientist, Pathology
School	Vc-health Sciences-schools
Address	9500 Gilman Drive # La Jolla CA 92093
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Bibliographic

selected publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice. J Clin Invest. 2025 Apr 04. Lin J, Callender JA, Mayfield JE, McClatchy DB, Ojeda-Juárez D, Pourhamzeh M, Soldau K, Kurt TD, Danque GA, Khuu H, Ronson JE, Pizzo DP, Du Y, Gruber MA, Sevillano AM, Wang J, Orrú CD, Chen J, Funk G, Aguilar-Calvo P, Aulston BD, Roy S, Rho JM, Bui JD, Newton AC, Lipton SA, Caughey B, Patrick GN, Doré K, Yates JR, Sigurdson CJ. PMID: 40185484.

View in: PubMed Mentions: Fields:
Med Medicine (General)
Mutant prion protein enhances NMDA receptor activity, activates PKC, and triggers rapid excitotoxicity in mice. J Clin Invest. 2025 May 15; 135(10). Lin J, Callender JA, Mayfield JE, McClatchy DB, Ojeda-Juárez D, Pourhamzeh M, Soldau K, Kurt TD, Danque GA, Khuu H, Ronson JE, Pizzo DP, Du Y, Gruber MA, Sevillano AM, Wang J, Orrú CD, Chen J, Funk G, Aguilar-Calvo P, Aulston BD, Roy S, Rho JM, Bui JD, Newton AC, Lipton SA, Caughey B, Patrick GN, Doré K, Yates JR, Sigurdson CJ. PMID: 40185484; PMCID: PMC12077891.

View in: PubMed Mentions: Fields:
Med Medicine (General)
Long term rescue of Alzheimer's deficits in vivo by one-time gene-editing of App C-terminus. bioRxiv. 2025 Jan 07. Aulston BD, Gimse K, Bazick HO, Kramar EA, Pizzo DP, Parra-Rivas LA, Sun J, Branes-Guerrero K, Checka N, Bagheri N, Satyadev N, Carlson-Stevermer J, Saito T, Saido TC, Audhya A, Wood MA, Zylka MJ, Saha K, Roy S. PMID: 38895278; PMCID: PMC11185791.

View in: PubMed Mentions:
Serine-129 phosphorylation of α-synuclein is an activity-dependent trigger for physiologic protein-protein interactions and synaptic function. Neuron. 2023 Dec 20; 111(24):4006-4023.e10. Parra-Rivas LA, Madhivanan K, Aulston BD, Wang L, Prakashchand DD, Boyer NP, Saia-Cereda VM, Branes-Guerrero K, Pizzo DP, Bagchi P, Sundar VS, Tang Y, Das U, Scott DA, Rangamani P, Ogawa Y. PMID: 38128479; PMCID: PMC10766085.

View in: PubMed Mentions: 40 Fields:
Neu Neurology
Translation:Humans Cells
Diminished Neuronal ESCRT-0 Function Exacerbates AMPA Receptor Derangement and Accelerates Prion-Induced Neurodegeneration. J Neurosci. 2023 05 24; 43(21):3970-3984. Lawrence JA, Aguilar-Calvo P, Ojeda-Juárez D, Khuu H, Soldau K, Pizzo DP, Wang J, Malik A, Shay TF, Sullivan EE, Aulston B, Song SM, Callender JA, Sanchez H, Geschwind MD, Roy S, Rissman RA, Trejo J, Tanaka N, Wu C, Chen X, Patrick GN, Sigurdson CJ. PMID: 37019623; PMCID: PMC10219035.

View in: PubMed Mentions: 5 Fields:
Neu Neurology
Translation:Humans Animals Cells
Mutant Presenilin 1 Dysregulates Exosomal Proteome Cargo Produced by Human-Induced Pluripotent Stem Cell Neurons. ACS Omega. 2021 May 25; 6(20):13033-13056. Podvin S, Jones A, Liu Q, Aulston B, Mosier C, Ames J, Winston C, Lietz CB, Jiang Z, O'Donoghue AJ, Ikezu T, Rissman RA, Yuan SH, Hook V. PMID: 34056454; PMCID: PMC8158845.

View in: PubMed Mentions: 6
Dysregulation of Exosome Cargo by Mutant Tau Expressed in Human-induced Pluripotent Stem Cell (iPSC) Neurons Revealed by Proteomics Analyses. Mol Cell Proteomics. 2020 06; 19(6):1017-1034. Podvin S, Jones A, Liu Q, Aulston B, Ransom L, Ames J, Shen G, Lietz CB, Jiang Z, O'Donoghue AJ, Winston C, Ikezu T, Rissman RA, Yuan S, Hook V. PMID: 32295833; PMCID: PMC7261814.

View in: PubMed Mentions: 21 Fields:
Bio Biochemistry Cel Cell Biology Mol Molecular Biology
Translation:Humans Animals Cells
An In Vitro Model for Studying Tau Aggregation Using Lentiviral-mediated Transduction of Human Neurons. J Vis Exp. 2019 05 23; (147). Aulston B, Liu Q, Reilly P, Yuan SH. PMID: 31180362.

View in: PubMed Mentions: 2 Fields:
Bio Biology Med Medicine (General)
Translation:Humans Animals Cells
Extracellular Vesicles Isolated from Familial Alzheimer's Disease Neuronal Cultures Induce Aberrant Tau Phosphorylation in the Wild-Type Mouse Brain. J Alzheimers Dis. 2019; 72(2):575-585. Aulston B, Liu Q, Mante M, Florio J, Rissman RA, Yuan SH. PMID: 31594233; PMCID: PMC8373022.

View in: PubMed Mentions: 32 Fields:
Ger Geriatrics Neu Neurology
Translation:Humans Animals Cells
Neuronal Exosome-Derived Human Tau is Toxic to Recipient Mouse Neurons in vivo. J Alzheimers Dis. 2019; 67(2):541-553. Winston CN, Aulston B, Rockenstein EM, Adame A, Prikhodko O, Dave KN, Mishra P, Rissman RA, Yuan SH. PMID: 30584143; PMCID: PMC8373009.

View in: PubMed Mentions: 49 Fields:
Ger Geriatrics Neu Neurology
Translation:Humans Animals Cells
Secreted amyloid precursor protein alpha activates neuronal insulin receptors and prevents diabetes-induced encephalopathy. Exp Neurol. 2018 05; 303:29-37. Aulston BD, Schapansky J, Huang Y, Odero GL, Glazner GW. PMID: 29410317.

View in: PubMed Mentions: 4 Fields:
Neu Neurology
Translation:Animals Cells
Normalization of NF-κB activity in dorsal root ganglia neurons cultured from diabetic rats reverses neuropathy-linked markers of cellular pathology. Exp Neurol. 2013 Mar; 241:169-78. Saleh A, Schapansky J, Smith DR, Young N, Odero GL, Aulston B, Fernyhough P, Glazner GW. PMID: 23159890.

View in: PubMed Mentions: 5 Fields:
Neu Neurology
Translation:Animals Cells