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    Paul Jensen

    Address9500 Gilman Drive #0204
    CA La Jolla 92093
    Phone858-534-7322
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      Collapse Research 
      Collapse Research Activities and Funding
      Scripps Center for Ocean and Human Health
      NIH/NIEHS P01ES021921Sep 24, 2012 - Jul 31, 2017
      Role: Co-Investigator
      A sequenced-based approach for improved small molecule discovery
      NIH/NIGMS R01GM086261Aug 1, 2010 - May 31, 2014
      Role: Principal Investigator
      Natural Product Genome Mining
      NIH/NIGMS R01GM085770Aug 1, 2009 - Jul 31, 2021
      Role: Principal Investigator
      Exploration, conservation, & development of marine biodiversity in Fiji and the S
      NIH U19TW007401Sep 29, 2005 - Jul 31, 2019
      Role: Co-Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Bruns H, Crüsemann M, Letzel AC, Alanjary M, McInerney JO, Jensen P, Schulz S, Moore BS, Ziemert N. Function-related replacement of bacterial siderophore pathways. ISME J. 2017 Aug 15. PMID: 28809850.
        View in: PubMed
      2. Letzel AC, Li J, Amos GCA, Millán-Aguiñaga N, Ginigini J, Abdelmohsen UR, Gaudêncio SP, Ziemert N, Moore BS, Jensen P. Genomic insights into specialized metabolism in the marine actinomycete Salinispora. Environ Microbiol. 2017 Jul 28. PMID: 28752948.
        View in: PubMed
      3. Millán-Aguiñaga N, Chavarria KL, Ugalde JA, Letzel AC, Rouse GW, Jensen P. Phylogenomic Insight into Salinispora (Bacteria, Actinobacteria) Species Designations. Sci Rep. 2017 Jun 15; 7(1):3564. PMID: 28620214.
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      4. Gallagher KA, Wanger G, Henderson J, Llorente M, Hughes CC, Jensen P. Ecological implications of hypoxia-triggered shifts in secondary metabolism. Environ Microbiol. 2017 Jun; 19(6):2182-2191. PMID: 28205416.
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      5. Asolkar RN, Singh A, Jensen P, Aalbersberg W, Carté BK, Feussner KD, Subramani R, DiPasquale A, Rheingold AL, Fenical W. Marinocyanins, cytotoxic bromo-phenazinone meroterpenoids from a marine bacterium from the streptomycete clade MAR4. Tetrahedron. 2017 Apr 20; 73(16):2234-2241. PMID: 28814819.
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      6. Jensen P. Review of Microbial Ecology Microbial Ecology . Edited by L. L. Barton and D. E. Northup. Wiley-Blackwell , Hoboken, NJ, USA . 2011 . 440 pp. $116.95 (Hardcover). ISBN 978-0-470-04817-7 . J Nat Prod. 2017 Jan 27; 80(1):232. PMID: 28079377.
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      7. Patin NV, Schorn M, Aguinaldo K, Lincecum T, Moore BS, Jensen P. Effects of actinomycete secondary metabolites on sediment microbial communities. Appl Environ Microbiol. 2016 Dec 16. PMID: 27986719.
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      8. Schorn MA, Alanjary MM, Aguinaldo K, Korobeynikov A, Podell S, Patin N, Lincecum T, Jensen P, Ziemert N, Moore BS. Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters. Microbiology. 2016 Dec; 162(12):2075-2086. PMID: 27902408.
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      9. Floros DJ, Jensen P, Dorrestein PC, Koyama N. A metabolomics guided exploration of marine natural product chemical space. Metabolomics. 2016 Sep; 12(9). PMID: 28819353.
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      10. Jensen P. Natural Products and the Gene Cluster Revolution. Trends Microbiol. 2016 Dec; 24(12):968-977. PMID: 27491886.
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      11. Gallagher KA, Jensen P. Genomic insights into the evolution of hybrid isoprenoid biosynthetic gene clusters in the MAR4 marine streptomycete clade. BMC Genomics. 2015; 16(1):960. PMID: 26578069; PMCID: PMC4650096.
      12. Rückert C, Leipoldt F, Zeyhle P, Fenical W, Jensen P, Kalinowski J, Heide L, Kaysser L. Complete genome sequence of Streptomyces sp. CNQ-509, a prolific producer of meroterpenoid chemistry. J Biotechnol. 2015 Dec 20; 216:140-1. PMID: 26319318.
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      13. Choi EJ, Nam SJ, Paul L, Beatty D, Kauffman CA, Jensen P, Fenical W. Previously Uncultured Marine Bacteria Linked to Novel Alkaloid Production. Chem Biol. 2015 Sep 17; 22(9):1270-9. PMID: 26299672.
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      14. Patin NV, Duncan KR, Dorrestein PC, Jensen P. Competitive strategies differentiate closely related species of marine actinobacteria. ISME J. 2016 Feb; 10(2):478-90. PMID: 26241505.
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      15. Nam SJ, Kauffman CA, Jensen P, Moore CE, Rheingold AL, Fenical W. Actinobenzoquinoline and Actinophenanthrolines A-C, Unprecedented Alkaloids from a Marine Actinobacterium. Org Lett. 2015 Jul 2; 17(13):3240-3. PMID: 26084575.
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      16. Jensen P, Moore BS, Fenical W. The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery. Nat Prod Rep. 2015 Apr 29; 32(5):738-51. PMID: 25730728.
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      17. Duncan KR, Crüsemann M, Lechner A, Sarkar A, Li J, Ziemert N, Wang M, Bandeira N, Moore BS, Dorrestein PC, Jensen P. Molecular Networking and Pattern-Based Genome Mining Improves Discovery of Biosynthetic Gene Clusters and their Products from Salinispora Species. Chem Biol. 2015 Apr 23; 22(4):460-71. PMID: 25865308.
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      18. Wietz M, Millán-Aguiñaga N, Jensen P. CRISPR-Cas systems in the marine actinomycete Salinispora: linkages with phage defense, microdiversity and biogeography. BMC Genomics. 2014; 15:936. PMID: 25344663; PMCID: PMC4223832.
      19. Ziemert N, Lechner A, Wietz M, Millán-Aguiñaga N, Chavarria KL, Jensen P. Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora. Proc Natl Acad Sci U S A. 2014 Mar 25; 111(12):E1130-9. PMID: 24616526; PMCID: PMC3970525.
      20. Farnaes L, Coufal NG, Kauffman CA, Rheingold AL, Dipasquale AG, Jensen P, Fenical W. Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis. J Nat Prod. 2014 Jan 24; 77(1):15-21. PMID: 24328269.
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      21. Nam SJ, Kauffman CA, Paul LA, Jensen P, Fenical W. Actinoranone, a cytotoxic meroterpenoid of unprecedented structure from a marine adapted Streptomyces sp. Org Lett. 2013 Nov 1; 15(21):5400-3. PMID: 24152065.
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      22. Jensen P, Chavarria KL, Fenical W, Moore BS, Ziemert N. Challenges and triumphs to genomics-based natural product discovery. J Ind Microbiol Biotechnol. 2014 Feb; 41(2):203-9. PMID: 24104399.
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      23. Gallagher KA, Rauscher K, Pavan Ioca L, Jensen P. Phylogenetic and chemical diversity of a hybrid-isoprenoid-producing streptomycete lineage. Appl Environ Microbiol. 2013 Nov; 79(22):6894-902. PMID: 23995934; PMCID: PMC3811536.
      24. Zafrir Ilan E, Torres MR, Prudhomme J, Le Roch K, Jensen P, Fenical W. Farnesides A and B, sesquiterpenoid nucleoside ethers from a marine-derived Streptomyces sp., strain CNT-372 from Fiji. J Nat Prod. 2013 Sep 27; 76(9):1815-8. PMID: 23987585.
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      25. Freel KC, Millán-Aguiñaga N, Jensen P. Multilocus sequence typing reveals evidence of homologous recombination linked to antibiotic resistance in the genus Salinispora. Appl Environ Microbiol. 2013 Oct; 79(19):5997-6005. PMID: 23892741; PMCID: PMC3811353.
      26. Wietz M, Duncan K, Patin NV, Jensen P. Antagonistic interactions mediated by marine bacteria: the role of small molecules. J Chem Ecol. 2013 Jul; 39(7):879-91. PMID: 23852047.
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      27. Cheng YB, Jensen P, Fenical W. Cytotoxic and Antimicrobial Napyradiomycins from Two Marine-Derived, MAR 4 Streptomyces Strains. European J Org Chem. 2013 Jun 1; 2013(18). PMID: 24376369.
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      28. Prieto-Davó A, Villarreal-Gómez LJ, Forschner-Dancause S, Bull AT, Stach JE, Smith DC, Rowley DC, Jensen P. Targeted search for actinomycetes from nearshore and deep-sea marine sediments. FEMS Microbiol Ecol. 2013 Jun; 84(3):510-8. PMID: 23360553; NIHMSID: NIHMS440803.
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      29. Lane AL, Nam SJ, Fukuda T, Yamanaka K, Kauffman CA, Jensen P, Fenical W, Moore BS. Structures and comparative characterization of biosynthetic gene clusters for cyanosporasides, enediyne-derived natural products from marine actinomycetes. J Am Chem Soc. 2013 Mar 20; 135(11):4171-4. PMID: 23458364.
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      30. Alvarez-Mico X, Jensen P, Fenical W, Hughes CC. Chlorizidine, a cytotoxic 5H-pyrrolo[2,1-a]isoindol-5-one-containing alkaloid from a marine Streptomyces sp. Org Lett. 2013 Mar 1; 15(5):988-91. PMID: 23405849.
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      31. Ahmed L, Jensen P, Freel KC, Brown R, Jones AL, Kim BY, Goodfellow M. Salinispora pacifica sp. nov., an actinomycete from marine sediments. Antonie Van Leeuwenhoek. 2013 May; 103(5):1069-78. PMID: 23361994.
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      32. Becerril-Espinosa A, Freel KC, Jensen P, Soria-Mercado IE. Marine Actinobacteria from the Gulf of California: diversity, abundance and secondary metabolite biosynthetic potential. Antonie Van Leeuwenhoek. 2013 Apr; 103(4):809-19. PMID: 23229438; NIHMSID: NIHMS705897.
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      33. Haste NM, Thienphrapa W, Tran DN, Loesgen S, Sun P, Nam SJ, Jensen P, Fenical W, Sakoulas G, Nizet V, Hensler ME. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2012 Dec; 65(12):593-8. PMID: 23047246.
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      34. Kaysser L, Bernhardt P, Nam SJ, Loesgen S, Ruby JG, Skewes-Cox P, Jensen P, Fenical W, Moore BS. Merochlorins A-D, cyclic meroterpenoid antibiotics biosynthesized in divergent pathways with vanadium-dependent chloroperoxidases. J Am Chem Soc. 2012 Jul 25; 134(29):11988-91. PMID: 22784372.
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      35. Choi EJ, Beatty DS, Paul LA, Fenical W, Jensen P. Mooreia alkaloidigena gen. nov., sp. nov. and Catalinimonas alkaloidigena gen. nov., sp. nov., alkaloid-producing marine bacteria in the proposed families Mooreiaceae fam. nov. and Catalimonadaceae fam. nov. in the phylum Bacteroidetes. Int J Syst Evol Microbiol. 2013 Apr; 63(Pt 4):1219-28. PMID: 22753528.
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      36. Gonzalez DJ, Xu Y, Yang YL, Esquenazi E, Liu WT, Edlund A, Duong T, Du L, Molnár I, Gerwick WH, Jensen P, Fischbach M, Liaw CC, Straight P, Nizet V, Dorrestein PC. Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes. J Proteomics. 2012 Aug 30; 75(16):5069-76. PMID: 22641157.
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      37. Bucarey SA, Penn K, Paul L, Fenical W, Jensen P. Genetic complementation of the obligate marine actinobacterium Salinispora tropica with the large mechanosensitive channel gene mscL rescues cells from osmotic downshock. Appl Environ Microbiol. 2012 Jun; 78(12):4175-82. PMID: 22492446.
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      38. Ziemert N, Podell S, Penn K, Badger JH, Allen E, Jensen P. The natural product domain seeker NaPDoS: a phylogeny based bioinformatic tool to classify secondary metabolite gene diversity. PLoS One. 2012; 7(3):e34064. PMID: 22479523; PMCID: PMC3315503.
      39. Penn K, Jensen P. Comparative genomics reveals evidence of marine adaptation in Salinispora species. BMC Genomics. 2012; 13:86. PMID: 22401625; PMCID: PMC3314556.
      40. Sakoulas G, Nam SJ, Loesgen S, Fenical W, Jensen P, Nizet V, Hensler M. Novel bacterial metabolite merochlorin A demonstrates in vitro activity against multi-drug resistant methicillin-resistant Staphylococcus aureus. PLoS One. 2012; 7(1):e29439. PMID: 22279537.
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      41. Ziemert N, Jensen P. Phylogenetic approaches to natural product structure prediction. Methods Enzymol. 2012; 517:161-82. PMID: 23084938; NIHMSID: NIHMS705909.
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      42. Freel KC, Edlund A, Jensen P. Microdiversity and evidence for high dispersal rates in the marine actinomycete 'Salinispora pacifica'. Environ Microbiol. 2012 Feb; 14(2):480-93. PMID: 22117917; NIHMSID: NIHMS333153.
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      43. Nam SJ, Kauffman CA, Jensen P, Fenical W. Isolation and Characterization of Actinoramides A-C, Highly Modified Peptides from a Marine Streptomyces sp. Tetrahedron. 2011 Sep 2; 67(35):6707-6712. PMID: 21857753.
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      44. Freel KC, Nam SJ, Fenical W, Jensen P. Evolution of secondary metabolite genes in three closely related marine actinomycete species. Appl Environ Microbiol. 2011 Oct; 77(20):7261-70. PMID: 21873479.
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      45. Miyanaga A, Janso JE, McDonald L, He M, Liu H, Barbieri L, Eustáquio AS, Fielding EN, Carter GT, Jensen P, Feng X, Leighton M, Koehn FE, Moore BS. Discovery and assembly-line biosynthesis of the lymphostin pyrroloquinoline alkaloid family of mTOR inhibitors in Salinispora bacteria. J Am Chem Soc. 2011 Aug 31; 133(34):13311-3. PMID: 21815669.
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      46. Fukuda T, Miller ED, Clark BR, Alnauman A, Murphy CD, Jensen P, Fenical W. Structures and biosynthesis of the pyridinopyrones, polyenepyrones from a marine-derived Streptomyces species. J Nat Prod. 2011 Aug 26; 74(8):1773-8. PMID: 21751787.
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      47. Edlund A, Loesgen S, Fenical W, Jensen P. Geographic distribution of secondary metabolite genes in the marine actinomycete Salinispora arenicola. Appl Environ Microbiol. 2011 Sep; 77(17):5916-25. PMID: 21724881.
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      48. Sun P, Maloney KN, Nam SJ, Haste NM, Raju R, Aalbersberg W, Jensen P, Nizet V, Hensler ME, Fenical W. Fijimycins A-C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp. Bioorg Med Chem. 2011 Nov 15; 19(22):6557-62. PMID: 21745747.
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      49. Field LD, Li HL, Dalgarno SJ, Jensen P, McIntosh RD. Synthesis and characterization of iron(II) and ruthenium(II) hydrido hydrazine complexes. Inorg Chem. 2011 Jun 20; 50(12):5468-76. PMID: 21618998.
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      50. Haste NM, Hughes CC, Tran DN, Fenical W, Jensen P, Nizet V, Hensler ME. Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2011 Jul; 55(7):3305-12. PMID: 21502631.
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      51. Potts BC, Albitar MX, Anderson KC, Baritaki S, Berkers C, Bonavida B, Chandra J, Chauhan D, Cusack JC, Fenical W, Ghobrial IM, Groll M, Jensen P, Lam KS, Lloyd GK, McBride W, McConkey DJ, Miller CP, Neuteboom ST, Oki Y, Ovaa H, Pajonk F, Richardson PG, Roccaro AM, Sloss CM, Spear MA, Valashi E, Younes A, Palladino MA. Marizomib, a proteasome inhibitor for all seasons: preclinical profile and a framework for clinical trials. Curr Cancer Drug Targets. 2011 Mar; 11(3):254-84. PMID: 21247382; NIHMSID: NIHMS475931.
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      52. Wilson MC, Nam SJ, Gulder TA, Kauffman CA, Jensen P, Fenical W, Moore BS. Structure and biosynthesis of the marine streptomycete ansamycin ansalactam A and its distinctive branched chain polyketide extender unit. J Am Chem Soc. 2011 Feb 16; 133(6):1971-7. PMID: 21247149.
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      53. Eustáquio AS, Nam SJ, Penn K, Lechner A, Wilson MC, Fenical W, Jensen P, Moore BS. The discovery of salinosporamide K from the marine bacterium "Salinispora pacifica" by genome mining gives insight into pathway evolution. Chembiochem. 2011 Jan 3; 12(1):61-4. PMID: 21154492.
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      54. Kwon HC, Espindola AP, Park JS, Prieto-Davó A, Rose M, Jensen P, Fenical W. Nitropyrrolins A-E, cytotoxic farnesyl-a-nitropyrroles from a marine-derived bacterium within the actinomycete family Streptomycetaceae. J Nat Prod. 2010 Dec 27; 73(12):2047-52. PMID: 21090803.
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      55. Gallagher KA, Fenical W, Jensen P. Hybrid isoprenoid secondary metabolite production in terrestrial and marine actinomycetes. Curr Opin Biotechnol. 2010 Dec; 21(6):794-800. PMID: 20951024.
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      56. Nam SJ, Gaudêncio SP, Kauffman CA, Jensen P, Kondratyuk TP, Marler LE, Pezzuto JM, Fenical W. Fijiolides A and B, inhibitors of TNF-alpha-induced NFkappaB activation, from a marine-derived sediment bacterium of the genus Nocardiopsis. J Nat Prod. 2010 Jun 25; 73(6):1080-6. PMID: 20481500.
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      57. Murphy BT, Narender T, Kauffman CA, Woolery M, Jensen P, Fenical W. Saliniquinones A-F, New Members of the Highly Cytotoxic Anthraquinone-?-Pyrones from the Marine Actinomycete Salinispora arenicola. Aust J Chem. 2010 Jun 1; 63(6). PMID: 24223427.
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      58. Oh H, Jensen P, Murphy BT, Fiorilla C, Sullivan JF, Ramsey T, Fenical W. Cryptosphaerolide, a cytotoxic Mcl-1 inhibitor from a marine-derived ascomycete related to the genus Cryptosphaeria. J Nat Prod. 2010 May 28; 73(5):998-1001. PMID: 20462271.
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      59. Hughes CC, Kauffman CA, Jensen P, Fenical W. Structures, reactivities, and antibiotic properties of the marinopyrroles A-F. J Org Chem. 2010 May 21; 75(10):3240-50. PMID: 20405892.
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      60. Haste NM, Perera VR, Maloney KN, Tran DN, Jensen P, Fenical W, Nizet V, Hensler ME. Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus. J Antibiot (Tokyo). 2010 May; 63(5):219-24. PMID: 20339399.
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      61. Meyer SW, Mordhorst TF, Lee C, Jensen P, Fenical W, Köck M. Penilumamide, a novel lumazine peptide isolated from the marine-derived fungus, Penicillium sp. CNL-338. Org Biomol Chem. 2010 May 7; 8(9):2158-63. PMID: 20401392; NIHMSID: NIHMS475876.
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      62. Gontang EA, Gaudêncio SP, Fenical W, Jensen P. Sequence-based analysis of secondary-metabolite biosynthesis in marine actinobacteria. Appl Environ Microbiol. 2010 Apr; 76(8):2487-99. PMID: 20154113.
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      63. Clegg JK, Iremonger SS, Hayter MJ, Southon PD, Macquart RB, Duriska MB, Jensen P, Turner P, Jolliffe KA, Kepert CJ, Meehan GV, Lindoy LF. Hierarchical self-assembly of a chiral metal-organic framework displaying pronounced porosity. Angew Chem Int Ed Engl. 2010 Feb 1; 49(6):1075-8. PMID: 20058285.
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      64. Jensen P. Linking species concepts to natural product discovery in the post-genomic era. J Ind Microbiol Biotechnol. 2010 Mar; 37(3):219-24. PMID: 20033830; PMCID: PMC2820216.
      65. Maloney KN, Macmillan JB, Kauffman CA, Jensen P, Dipasquale AG, Rheingold AL, Fenical W. Lodopyridone, a structurally unprecedented alkaloid from a marine actinomycete. Org Lett. 2009 Dec 3; 11(23):5422-4. PMID: 19883103.
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      66. Asolkar RN, Kirkland TN, Jensen P, Fenical W. Arenimycin, an antibiotic effective against rifampin- and methicillin-resistant Staphylococcus aureus from the marine actinomycete Salinispora arenicola. J Antibiot (Tokyo). 2010 Jan; 63(1):37-9. PMID: 19927167.
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      67. Penn K, Jenkins C, Nett M, Udwary DW, Gontang EA, McGlinchey RP, Foster B, Lapidus A, Podell S, Allen EE, Moore BS, Jensen P. Genomic islands link secondary metabolism to functional adaptation in marine Actinobacteria. ISME J. 2009 Oct; 3(10):1193-203. PMID: 19474814.
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      68. Strangman WK, Kwon HC, Broide D, Jensen P, Fenical W. Potent inhibitors of pro-inflammatory cytokine production produced by a marine-derived bacterium. J Med Chem. 2009 Apr 23; 52(8):2317-27. PMID: 19323483.
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      69. Asolkar RN, Freel KC, Jensen P, Fenical W, Kondratyuk TP, Park EJ, Pezzuto JM. Arenamides A-C, cytotoxic NFkappaB inhibitors from the marine actinomycete Salinispora arenicola. J Nat Prod. 2009 Mar 27; 72(3):396-402. PMID: 19117399.
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      70. Kwon HC, Kauffman CA, Jensen P, Fenical W. Marinisporolides, polyene-polyol macrolides from a marine actinomycete of the new genus Marinispora. J Org Chem. 2009 Jan 16; 74(2):675-84. PMID: 19132943.
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      71. Hanson GR, Jensen P, McMurtrie J, Rintoul L, Micallef AS. Halogen bonding between an isoindoline nitroxide and 1,4-diiodotetrafluorobenzene: new tools and tectons for self-assembling organic spin systems. Chemistry. 2009; 15(16):4156-64. PMID: 19283822.
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      72. Hughes CC, MacMillan JB, Gaudêncio SP, Jensen P, Fenical W. The ammosamides: structures of cell cycle modulators from a marine-derived Streptomyces species. Angew Chem Int Ed Engl. 2009; 48(4):725-7. PMID: 19090514.
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      73. Boonlarppradab C, Kauffman CA, Jensen P, Fenical W. Marineosins A and B, cytotoxic spiroaminals from a marine-derived actinomycete. Org Lett. 2008 Dec 18; 10(24):5505-8. PMID: 19007176.
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      74. Fenical W, Jensen P, Palladino MA, Lam KS, Lloyd GK, Potts BC. Discovery and development of the anticancer agent salinosporamide A (NPI-0052). Bioorg Med Chem. 2009 Mar 15; 17(6):2175-80. PMID: 19022674.
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      75. Newton GL, Jensen P, Macmillan JB, Fenical W, Fahey RC. An N-acyl homolog of mycothiol is produced in marine actinomycetes. Arch Microbiol. 2008 Nov; 190(5):547-57. PMID: 18629474.
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      76. Prudhomme J, McDaniel E, Ponts N, Bertani S, Fenical W, Jensen P, Le Roch K. Marine actinomycetes: a new source of compounds against the human malaria parasite. PLoS One. 2008; 3(6):e2335. PMID: 18523554; PMCID: PMC2391291.
      77. Jensen P, Lauro FM. An assessment of actinobacterial diversity in the marine environment. Antonie Van Leeuwenhoek. 2008 Jun; 94(1):51-62. PMID: 18500568; NIHMSID: NIHMS380765.
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      78. Schultz AW, Oh DC, Carney JR, Williamson RT, Udwary DW, Jensen P, Gould SJ, Fenical W, Moore BS. Biosynthesis and structures of cyclomarins and cyclomarazines, prenylated cyclic peptides of marine actinobacterial origin. J Am Chem Soc. 2008 Apr 2; 130(13):4507-16. PMID: 18331040.
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      79. Oh DC, Gontang EA, Kauffman CA, Jensen P, Fenical W. Salinipyrones and pacificanones, mixed-precursor polyketides from the marine actinomycete Salinispora pacifica. J Nat Prod. 2008 Apr; 71(4):570-5. PMID: 18321059.
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      80. Hughes CC, Prieto-Davo A, Jensen P, Fenical W. The marinopyrroles, antibiotics of an unprecedented structure class from a marine Streptomyces sp. Org Lett. 2008 Feb 21; 10(4):629-31. PMID: 18205372.
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      81. Martin GD, Tan LT, Jensen P, Dimayuga RE, Fairchild CR, Raventos-Suarez C, Fenical W. Marmycins A and B, cytotoxic pentacyclic C-glycosides from a marine sediment-derived actinomycete related to the genus Streptomyces. J Nat Prod. 2007 Sep; 70(9):1406-9. PMID: 17844998.
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      82. Cho JY, Williams PG, Kwon HC, Jensen P, Fenical W. Lucentamycins A-D, cytotoxic peptides from the marine-derived actinomycete Nocardiopsis lucentensis. J Nat Prod. 2007 Aug; 70(8):1321-8. PMID: 17630797.
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      83. Udwary DW, Zeigler L, Asolkar RN, Singan V, Lapidus A, Fenical W, Jensen P, Moore BS. Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica. Proc Natl Acad Sci U S A. 2007 Jun 19; 104(25):10376-81. PMID: 17563368.
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      84. Gontang EA, Fenical W, Jensen P. Phylogenetic diversity of gram-positive bacteria cultured from marine sediments. Appl Environ Microbiol. 2007 May; 73(10):3272-82. PMID: 17400789.
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      85. Oh DC, Strangman WK, Kauffman CA, Jensen P, Fenical W. Thalassospiramides A and B, immunosuppressive peptides from the marine bacterium Thalassospira sp. Org Lett. 2007 Apr 12; 9(8):1525-8. PMID: 17373804.
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      86. Oh DC, Kauffman CA, Jensen P, Fenical W. Induced production of emericellamides A and B from the marine-derived fungus Emericella sp. in competing co-culture. J Nat Prod. 2007 Apr; 70(4):515-20. PMID: 17323993.
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      87. Williams PG, Miller ED, Asolkar RN, Jensen P, Fenical W. Arenicolides A-C, 26-membered ring macrolides from the marine actinomycete Salinispora arenicola. J Org Chem. 2007 Jul 6; 72(14):5025-34. PMID: 17266372.
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      88. Miller ED, Kauffman CA, Jensen P, Fenical W. Piperazimycins: cytotoxic hexadepsipeptides from a marine-derived bacterium of the genus Streptomyces. J Org Chem. 2007 Jan 19; 72(2):323-30. PMID: 17221946.
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      89. Williams PG, Asolkar RN, Kondratyuk T, Pezzuto JM, Jensen P, Fenical W. Saliniketals A and B, bicyclic polyketides from the marine actinomycete Salinispora arenicola. J Nat Prod. 2007 Jan; 70(1):83-8. PMID: 17253854.
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      91. Asolkar RN, Jensen P, Kauffman CA, Fenical W. Daryamides A-C, weakly cytotoxic polyketides from a marine-derived actinomycete of the genus Streptomyces strain CNQ-085. J Nat Prod. 2006 Dec; 69(12):1756-9. PMID: 17190455.
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      92. Fenical W, Jensen P. Developing a new resource for drug discovery: marine actinomycete bacteria. Nat Chem Biol. 2006 Dec; 2(12):666-73. PMID: 17108984.
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      93. Bugni TS, Woolery M, Kauffman CA, Jensen P, Fenical W. Bohemamines from a marine-derived Streptomyces sp. J Nat Prod. 2006 Nov; 69(11):1626-8. PMID: 17125235.
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      94. Jensen P, Mafnas C. Biogeography of the marine actinomycete Salinispora. Environ Microbiol. 2006 Nov; 8(11):1881-8. PMID: 17014488.
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      95. Cho JY, Kwon HC, Williams PG, Jensen P, Fenical W. Azamerone, a terpenoid phthalazinone from a marine-derived bacterium related to the genus Streptomyces (Actinomycetales). Org Lett. 2006 Jun 8; 8(12):2471-4. PMID: 16737291.
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      96. Oh DC, Williams PG, Kauffman CA, Jensen P, Fenical W. Cyanosporasides A and B, chloro- and cyano-cyclopenta[a]indene glycosides from the marine actinomycete "Salinispora pacifica". Org Lett. 2006 Mar 16; 8(6):1021-4. PMID: 16524258.
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      97. Cho JY, Kwon HC, Williams PG, Kauffman CA, Jensen P, Fenical W. Actinofuranones A and B, polyketides from a marine-derived bacterium related to the genus streptomyces (actinomycetales). J Nat Prod. 2006 Mar; 69(3):425-8. PMID: 16562851.
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      98. Cueto M, MacMillan JB, Jensen P, Fenical W. Tropolactones A-D, four meroterpenoids from a marine-derived fungus of the genus Aspergillus. Phytochemistry. 2006 Aug; 67(16):1826-31. PMID: 16500687.
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      99. Kwon HC, Kauffman CA, Jensen P, Fenical W. Marinomycins A-D, antitumor-antibiotics of a new structure class from a marine actinomycete of the recently discovered genus "marinispora". J Am Chem Soc. 2006 Feb 8; 128(5):1622-32. PMID: 16448135.
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      100. Mincer TJ, Fenical W, Jensen P. Culture-dependent and culture-independent diversity within the obligate marine actinomycete genus Salinispora. Appl Environ Microbiol. 2005 Nov; 71(11):7019-28. PMID: 16269737.
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      101. Maldonado LA, Fenical W, Jensen P, Kauffman CA, Mincer TJ, Ward AC, Bull AT, Goodfellow M. Salinispora arenicola gen. nov., sp. nov. and Salinispora tropica sp. nov., obligate marine actinomycetes belonging to the family Micromonosporaceae. Int J Syst Evol Microbiol. 2005 Sep; 55(Pt 5):1759-66. PMID: 16166663.
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      102. Oh DC, Jensen P, Kauffman CA, Fenical W. Libertellenones A-D: induction of cytotoxic diterpenoid biosynthesis by marine microbial competition. Bioorg Med Chem. 2005 Sep 1; 13(17):5267-73. PMID: 15993608.
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      103. Williams PG, Buchanan GO, Feling RH, Kauffman CA, Jensen P, Fenical W. New cytotoxic salinosporamides from the marine Actinomycete Salinispora tropica. J Org Chem. 2005 Aug 5; 70(16):6196-203. PMID: 16050677.
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      104. Jensen P, Gontang E, Mafnas C, Mincer TJ, Fenical W. Culturable marine actinomycete diversity from tropical Pacific Ocean sediments. Environ Microbiol. 2005 Jul; 7(7):1039-48. PMID: 15946301.
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      105. Buchanan GO, Williams PG, Feling RH, Kauffman CA, Jensen P, Fenical W. Sporolides A and B: structurally unprecedented halogenated macrolides from the marine actinomycete Salinispora tropica. Org Lett. 2005 Jun 23; 7(13):2731-4. PMID: 15957933.
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      106. Macherla VR, Mitchell SS, Manam RR, Reed KA, Chao TH, Nicholson B, Deyanat-Yazdi G, Mai B, Jensen P, Fenical WF, Neuteboom ST, Lam KS, Palladino MA, Potts BC. Structure-activity relationship studies of salinosporamide A (NPI-0052), a novel marine derived proteasome inhibitor. J Med Chem. 2005 Jun 2; 48(11):3684-7. PMID: 15916417.
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      107. Soria-Mercado IE, Prieto-Davo A, Jensen P, Fenical W. Antibiotic terpenoid chloro-dihydroquinones from a new marine actinomycete. J Nat Prod. 2005 Jun; 68(6):904-10. PMID: 15974616.
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      108. Jensen P, Mincer TJ, Williams PG, Fenical W. Marine actinomycete diversity and natural product discovery. Antonie Van Leeuwenhoek. 2005 Jan; 87(1):43-8. PMID: 15726290.
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      109. Mincer TJ, Spyere A, Jensen P, Fenical W. Phylogenetic analyses and diterpenoid production by marine bacteria of the genus Saprospira. Curr Microbiol. 2004 Oct; 49(4):300-7. PMID: 15386120.
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      110. Rowley DC, Kelly S, Jensen P, Fenical W. Synthesis and structure-activity relationships of the halovirs, antiviral natural products from a marine-derived fungus. Bioorg Med Chem. 2004 Sep 15; 12(18):4929-36. PMID: 15336272.
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      111. Tan RX, Jensen P, Williams PG, Fenical W. Isolation and structure assignments of rostratins A-D, cytotoxic disulfides produced by the marine-derived fungus Exserohilum rostratum. J Nat Prod. 2004 Aug; 67(8):1374-82. PMID: 15332857.
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      112. Tan LT, Cheng XC, Jensen P, Fenical W. Scytalidamides A and B, new cytotoxic cyclic heptapeptides from a marine fungus of the genus Scytalidium. J Org Chem. 2003 Nov 14; 68(23):8767-73. PMID: 14604342.
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      113. Rowley DC, Kelly S, Kauffman CA, Jensen P, Fenical W. Halovirs A-E, new antiviral agents from a marine-derived fungus of the genus Scytalidium. Bioorg Med Chem. 2003 Sep 15; 11(19):4263-74. PMID: 12951157.
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      114. Liu Z, Jensen P, Fenical W. A cyclic carbonate and related polyketides from a marine-derived fungus of the genus Phoma. Phytochemistry. 2003 Sep; 64(2):571-4. PMID: 12943777.
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      115. Spyere A, Rowley DC, Jensen P, Fenical W. New neoverrucosane diterpenoids produced by the marine gliding bacterium Saprospira grandis. J Nat Prod. 2003 Jun; 66(6):818-22. PMID: 12828468.
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      116. Kubanek J, Jensen P, Keifer PA, Sullards MC, Collins DO, Fenical W. Seaweed resistance to microbial attack: a targeted chemical defense against marine fungi. Proc Natl Acad Sci U S A. 2003 Jun 10; 100(12):6916-21. PMID: 12756301; PMCID: PMC165804.
      117. Garo E, Starks CM, Jensen P, Fenical W, Lobkovsky E, Clardy J. Trichodermamides A and B, cytotoxic modified dipeptides from the marine-derived fungus Trichoderma virens. J Nat Prod. 2003 Mar; 66(3):423-6. PMID: 12662106.
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      118. Feling RH, Buchanan GO, Mincer TJ, Kauffman CA, Jensen P, Fenical W. Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora. Angew Chem Int Ed Engl. 2003 Jan 20; 42(3):355-7. PMID: 12548698.
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      119. Engel S, Jensen P, Fenical W. Chemical ecology of marine microbial defense. J Chem Ecol. 2002 Oct; 28(10):1971-85. PMID: 12474894.
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      120. Mincer TJ, Jensen P, Kauffman CA, Fenical W. Widespread and persistent populations of a major new marine actinomycete taxon in ocean sediments. Appl Environ Microbiol. 2002 Oct; 68(10):5005-11. PMID: 12324350.
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      121. Cueto M, Jensen P, Fenical W. Aspergilloxide, a novel sesterterpene epoxide from a marine-derived fungus of the genus Aspergillus. Org Lett. 2002 May 2; 4(9):1583-5. PMID: 11975634.
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      122. Cueto M, Jensen P, Kauffman C, Fenical W, Lobkovsky E, Clardy J. Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge. J Nat Prod. 2001 Nov; 64(11):1444-6. PMID: 11720529.
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      123. Cueto M, Jensen P, Fenical W. N-Methylsansalvamide, a cytotoxic cyclic depsipeptide from a marine fungus of the genus fusarium. Phytochemistry. 2000 Oct; 55(3):223-6. PMID: 11142846.
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      124. Koebmann BJ, Nilsson D, Kuipers OP, Jensen P. The membrane-bound H(+)-ATPase complex is essential for growth of Lactococcus lactis. J Bacteriol. 2000 Sep; 182(17):4738-43. PMID: 10940012; PMCID: PMC111348.
      125. Renner MK, Jensen P, Fenical W. Mangicols: structures and biosynthesis of A new class of sesterterpene polyols from a marine fungus of the genus Fusarium. J Org Chem. 2000 Aug 11; 65(16):4843-52. PMID: 10956462.
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      126. Belofsky GN, Anguera M, Jensen P, Fenical W, Köck M. Oxepinamides A-C and fumiquinazolines H--I: bioactive metabolites from a marine isolate of a fungus of the genus Acremonium. Chemistry. 2000 Apr 14; 6(8):1355-60. PMID: 10840958.
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      127. Jiang ZD, Jensen P, Fenical W. Lobophorins A and B, new antiinflammatory macrolides produced by a tropical marine bacterium. Bioorg Med Chem Lett. 1999 Jul 19; 9(14):2003-6. PMID: 10450970.
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      128. Cheng XC, Jensen P, Fenical W. Arenaric acid, a new pentacyclic polyether produced by a marine bacterium (Actinomycetales). J Nat Prod. 1999 Apr; 62(4):605-7. PMID: 10217719.
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      129. Cheng XC, Jensen P, Fenical W. Luisols A and B, new aromatic tetraols produced by an estuarine marine bacterium of the genus Streptomyces (Actinomycetales). J Nat Prod. 1999 Apr; 62(4):608-10. PMID: 10217720.
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      130. Jensen P, Jenkins KM, Porter D, Fenical W. Evidence that a New Antibiotic Flavone Glycoside Chemically Defends the Sea Grass Thalassia testudinum against Zoosporic Fungi. Appl Environ Microbiol. 1998 Jul; 64(7):2762. PMID: 16349564.
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      131. Jensen P, Jenkins KM, Porter D, Fenical W. Evidence that a New Antibiotic Flavone Glycoside Chemically Defends the Sea Grass Thalassia testudinum against Zoosporic Fungi. Appl Environ Microbiol. 1998 Apr; 64(4):1490-6. PMID: 16349549.
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      132. Long BH, Carboni JM, Wasserman AJ, Cornell LA, Casazza AM, Jensen P, Lindel T, Fenical W, Fairchild CR. Eleutherobin, a novel cytotoxic agent that induces tubulin polymerization, is similar to paclitaxel (Taxol). Cancer Res. 1998 Mar 15; 58(6):1111-5. PMID: 9515790.
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      133. Jensen P, Hammer K. The sequence of spacers between the consensus sequences modulates the strength of prokaryotic promoters. Appl Environ Microbiol. 1998 Jan; 64(1):82-7. PMID: 9435063; PMCID: PMC124675.
      134. Jensen P, Fenical W. The relative abundance and seawater requirements of gram-positive bacteria in near-shore tropical marine samples. Microb Ecol. 1995 May; 29(3):249-57. PMID: 24185344.
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      135. Snoep JL, Jensen P, Groeneveld P, Molenaar D, Kholodenko BN, Westerhoff HV. How to determine control of growth rate in a chemostat. Using metabolic control analysis to resolve the paradox. Biochem Mol Biol Int. 1994 Aug; 33(5):1023-32. PMID: 7987249.
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      136. Jensen P, Fenical W. Strategies for the discovery of secondary metabolites from marine bacteria: ecological perspectives. Annu Rev Microbiol. 1994; 48:559-84. PMID: 7826019.
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      137. Jensen P, Hammer K. Minimal Requirements for Exponential Growth of Lactococcus lactis. Appl Environ Microbiol. 1993 Dec; 59(12):4363-6. PMID: 16349136.
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      138. Jensen P, Dwight R, Fenical W. Distribution of actinomycetes in near-shore tropical marine sediments. Appl Environ Microbiol. 1991 Apr; 57(4):1102-8. PMID: 2059035.
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