-
Multi-omic analysis in carcinoma of unknown primary (CUP): therapeutic impact of knowing the unknown. Mol Oncol. 2022 Jul 22.
Kato S, Gumas S, Adashek JJ, Okamura R, Lee S, Sicklick JK, Kurzrock R. PMID: 35866362.
View in:
PubMed Mentions:
5 Fields:
-
Precision medicine-based therapies in advanced colorectal cancer: The University of California San Diego Molecular Tumor Board experience. Mol Oncol. 2022 07; 16(13):2575-2584.
Louie BH, Kato S, Kim KH, Lim HJ, Lee S, Okamura R, Fanta PT, Kurzrock R. PMID: 35238467; PMCID: PMC9251876.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Serial changes in liquid biopsy-derived variant allele frequency predict immune checkpoint inhibitor responsiveness in the pan-cancer setting. Oncoimmunology. 2022; 11(1):2052410.
Kato S, Li B, Adashek JJ, Cha SW, Bianchi-Frias D, Qian D, Kim L, So TW, Mitchell M, Kamei N, Hoiness R, Hoo J, Gray PN, Iyama T, Kashiwagi M, Lu HM, Kurzrock R. PMID: 35371621; PMCID: PMC8966985.
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PubMed Mentions:
6 Fields:
Translation:
Humans
-
Case series of outcomes in advanced cancer patients with single pathway alterations receiving N-of-One therapies. NPJ Precis Oncol. 2022 Mar 28; 6(1):18.
Gupta D, Kurzrock R, Lee S, Okamura R, Lim HJ, Kim KH, Sicklick JK, Kato S. PMID: 35347205; PMCID: PMC8960821.
View in:
PubMed Mentions:
1
-
Real-World Data From a Molecular Tumor Board: Improved Outcomes in Breast and Gynecologic Cancers Patients With Precision Medicine. JCO Precis Oncol. 2022 01; 6:e2000508.
Charo LM, Eskander RN, Sicklick J, Kim KH, Lim HJ, Okamura R, Lee S, Subramanian R, Schwab R, Shatsky R, Plaxe S, Kato S, Kurzrock R. PMID: 35005995; PMCID: PMC8769125.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Cetuximab in Patients with Non-Small Cell Lung Cancer and EGFR Exon 20 Insertion Alterations. Clin Oncol Case Rep. 2022 Jan; 5(1).
Nikanjam M, Kato S, Adashek JJ, Kurzrock R. PMID: 35403176; PMCID: PMC8994415.
View in:
PubMed Mentions:
1
-
Therapeutic Actionability of Circulating Cell-Free DNA Alterations in Carcinoma of Unknown Primary. JCO Precis Oncol. 2021; 5.
Kato S, Weipert C, Gumas S, Okamura R, Lee S, Sicklick JK, Saam J, Kurzrock R. PMID: 34778692; PMCID: PMC8585281.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
Hyperprogression in Gastric Cancer: Is MDM2 Amplification the Dark Horse? JCO Precis Oncol. 2021 11; 5:931-932.
Dayyani F, Kato S, Kurzrock R. PMID: 34994620.
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PubMed Mentions: Fields:
Translation:
Humans
-
Palbociclib as a Novel Therapy for Low-Grade Mucinous Carcinomatosis Peritonei of Appendiceal Origin. JCO Precis Oncol. 2021 11; 5:1069-1072.
Childers BG, Sood D, Patel R, Mose ES, Hosseini M, Kato S, Baumgartner JM, Lowy AM. PMID: 34994628.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
SMARCA4: Implications of an Altered Chromatin-Remodeling Gene for Cancer Development and Therapy. Mol Cancer Ther. 2021 12; 20(12):2341-2351.
Mardinian K, Adashek JJ, Botta GP, Kato S, Kurzrock R. PMID: 34642211; PMCID: PMC8643328.
View in:
PubMed Mentions:
33 Fields:
Translation:
HumansCells
-
Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study. Genome Med. 2021 10 04; 13(1):155.
Sicklick JK, Kato S, Okamura R, Patel H, Nikanjam M, Fanta PT, Hahn ME, De P, Williams C, Guido J, Solomon BM, McKay RR, Krie A, Boles SG, Ross JS, Lee JJ, Leyland-Jones B, Lippman SM, Kurzrock R. PMID: 34607609; PMCID: PMC8491393.
View in:
PubMed Mentions:
27 Fields:
Translation:
Humans
-
Location of Gastrointestinal Stromal Tumor (GIST) in the Stomach Predicts Tumor Mutation Profile and Drug Sensitivity. Clin Cancer Res. 2021 10 01; 27(19):5334-5342.
Sharma AK, de la Torre J, IJzerman NS, Sutton TL, Zhao B, Khan TM, Banerjee S, Cui C, Nguyen V, Alkhuziem M, Snaebjornsson P, van Boven H, Bruining A, Tang CM, Yoon H, De la Fuente A, Kato S, Patel H, Heinrich MC, Corless CL, Horgan S, Burgoyne AM, Fanta P, Mesirov JP, Blakely AM, Davis JL, Mayo SC, van Houdt WJ, Steeghs N, Sicklick JK. PMID: 34326133; PMCID: PMC8799780.
View in:
PubMed Mentions:
6 Fields:
Translation:
Humans
-
SWI/SNF complex alterations as a biomarker of immunotherapy efficacy in pancreatic cancer. JCI Insight. 2021 09 22; 6(18).
Botta GP, Kato S, Patel H, Fanta P, Lee S, Okamura R, Kurzrock R. PMID: 34375311; PMCID: PMC8492298.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Targeting ARID1A mutations in cancer. Cancer Treat Rev. 2021 Nov; 100:102287.
Mullen J, Kato S, Sicklick JK, Kurzrock R. PMID: 34619527.
View in:
PubMed Mentions:
38 Fields:
Translation:
HumansAnimals
-
A phase i study of ixazomib and erlotinib in patients with advanced solid tumors. Invest New Drugs. 2022 02; 40(1):99-105.
Kato S, Adashek JJ, Subbiah V, Fu S, Sun M, Nguyen L, Brown EJ, Yap TA, Karp DD, Piha-Paul SA, Hong DS. PMID: 34468905.
View in:
PubMed Mentions: Fields:
Translation:
HumansCTClinical Trials
-
Genome-wide Sequencing of Cell-free DNA Enables Detection of Copy-number Alterations in Patients with Cancer Where Tissue Biopsy is Not Feasible. Mol Cancer Ther. 2021 11; 20(11):2274-2279.
Jensen TJ, Goodman AM, Ellison CK, Holden KA, Kato S, Kim L, Daniels GA, Fitzgerald K, McCarthy E, Nakashe P, Mazloom AR, Almasri E, McLennan G, Grosu DS, Eisenberg M, Kurzrock R. PMID: 34465593.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns. Oncologist. 2021 09; 26(9):787-796.
Israel MA, Danziger N, McGregor KA, Murugesan K, Gjoerup O, Sokol ES, Tukachinsky H, Kurzrock R, Kato S, Sicklick JK, Nimeiri HS, Oxnard GR, Ross JS. PMID: 34080753; PMCID: PMC8417854.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
-
Did Everolimus Break the Rules? Clin Cancer Res. 2021 07 15; 27(14):3807-3808.
Kato S, Cohen EEW. PMID: 33986025.
View in:
PubMed Mentions:
1 Fields:
Translation:
Humans
-
Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation. Oncologist. 2021 07; 26(7):e1104-e1109.
Kim JW, Cardin DB, Vaishampayan UN, Kato S, Grossman SR, Glazer PM, Shyr Y, Ivy SP, LoRusso PM. PMID: 33742489; PMCID: PMC8265343.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Author Correction: COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials. Nat Rev Clin Oncol. 2021 May; 18(5):320.
Desai A, Gainor JF, Hegde A, Schram AM, Curigliano G, Pal S, Liu SV, Halmos B, Groisberg R, Grande E, Dragovich T, Matrana M, Agarwal N, Chawla S, Kato S, Morgan G, Kasi PM, Solomon B, Loong HH, Park H, Choueiri TK, Subbiah IM, Pemmaraju N, Subbiah V, COVID19 and Cancer Clinical Trials Working Group. PMID: 33758378; PMCID: PMC7985918.
View in:
PubMed Mentions:
3 Fields:
-
Functional measurement of mitogen-activated protein kinase pathway activation predicts responsiveness of RAS-mutant cancers to MEK inhibitors. Eur J Cancer. 2021 05; 149:184-192.
Kato S, Porter R, Okamura R, Lee S, Zelichov O, Tarcic G, Vidne M, Kurzrock R. PMID: 33865203.
View in:
PubMed Mentions:
2 Fields:
Translation:
HumansCells
-
Missing the target in cancer therapy. Nat Cancer. 2021 04; 2:369-371.
Adashek JJ, Goloubev A, Kato S, Kurzrock R. PMID: 34368781; PMCID: PMC8336921.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
COVID-19 vaccine guidance for patients with cancer participating in oncology clinical trials. Nat Rev Clin Oncol. 2021 05; 18(5):313-319.
Desai A, Gainor JF, Hegde A, Schram AM, Curigliano G, Pal S, Liu SV, Halmos B, Groisberg R, Grande E, Dragovich T, Matrana M, Agarwal N, Chawla S, Kato S, Morgan G, Kasi PM, Solomon B, Loong HH, Park H, Choueiri TK, Subbiah IM, Pemmaraju N, Subbiah V, COVID19 and Cancer Clinical Trials Working Group. PMID: 33723371; PMCID: PMC7957448.
View in:
PubMed Mentions:
62 Fields:
Translation:
HumansCellsPHPublic Health
-
KRAS-Mutated, Estrogen Receptor-Positive Low-Grade Serous Ovarian Cancer: Unraveling an Exceptional Response Mystery. Oncologist. 2021 04; 26(4):e530-e536.
Kato S, McFall T, Takahashi K, Bamel K, Ikeda S, Eskander RN, Plaxe S, Parker B, Stites E, Kurzrock R. PMID: 33528846; PMCID: PMC8018312.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
High prevalence of clonal hematopoiesis-type genomic abnormalities in cell-free DNA in invasive gliomas after treatment. Int J Cancer. 2021 06 01; 148(11):2839-2847.
Okamura R, Piccioni DE, Boichard A, Lee S, Jimenez RE, Sicklick JK, Kato S, Kurzrock R. PMID: 33497479; PMCID: PMC8048515.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Cancer of Unknown Primary in the Molecular Era. Trends Cancer. 2021 05; 7(5):465-477.
Kato S, Alsafar A, Walavalkar V, Hainsworth J, Kurzrock R. PMID: 33516660; PMCID: PMC8062281.
View in:
PubMed Mentions:
22 Fields:
Translation:
Humans
-
Concomitant MEK and Cyclin Gene Alterations: Implications for Response to Targeted Therapeutics. Clin Cancer Res. 2021 05 15; 27(10):2792-2797.
Kato S, Adashek JJ, Shaya J, Okamura R, Jimenez RE, Lee S, Sicklick JK, Kurzrock R. PMID: 33472910.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Targeting G1/S phase cell-cycle genomic alterations and accompanying co-alterations with individualized CDK4/6 inhibitor-based regimens. JCI Insight. 2021 01 11; 6(1).
Kato S, Okamura R, Adashek JJ, Khalid N, Lee S, Nguyen V, Sicklick JK, Kurzrock R. PMID: 33427211; PMCID: PMC7821594.
View in:
PubMed Mentions:
15 Fields:
Translation:
HumansCells
-
Immune profiling and immunotherapeutic targets in pancreatic cancer. Ann Transl Med. 2021 Jan; 9(2):119.
Lenzo FL, Kato S, Pabla S, DePietro P, Nesline MK, Conroy JM, Burgher B, Glenn ST, Kuvshinoff B, Kurzrock R, Morrison C. PMID: 33569421; PMCID: PMC7867882.
View in:
PubMed Mentions:
8
-
The Impact of COVID-19 on Cancer Clinical Trials Conducted by NCI-Designated Comprehensive Cancer Centers. J Immunother Precis Oncol. 2021 May; 4(2):56-63.
Gupta D, Kato S, Kurzrock R. PMID: 34337550; PMCID: PMC8320380.
View in:
PubMed Mentions:
5
-
Dose-escalation study of vemurafenib with sorafenib or crizotinib in patients with BRAF-mutated advanced cancers. Cancer. 2021 02 01; 127(3):391-402.
Janku F, Sakamuri D, Kato S, Huang HJ, Call SG, Naing A, Holley VR, Patel SP, Amaria RN, Falchook GS, Piha-Paul SA, Zinner RG, Tsimberidou AM, Hong DS, Meric-Bernstam F. PMID: 33119140.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy. Nat Commun. 2020 10 02; 11(1):4965.
Kato S, Kim KH, Lim HJ, Boichard A, Nikanjam M, Weihe E, Kuo DJ, Eskander RN, Goodman A, Galanina N, Fanta PT, Schwab RB, Shatsky R, Plaxe SC, Sharabi A, Stites E, Adashek JJ, Okamura R, Lee S, Lippman SM, Sicklick JK, Kurzrock R. PMID: 33009371; PMCID: PMC7532150.
View in:
PubMed Mentions:
100 Fields:
Translation:
Humans
-
Attrition of Patients on a Precision Oncology Trial: Analysis of the I-PREDICT Experience. Oncologist. 2020 11; 25(11):e1803-e1806.
Bohan SS, Sicklick JK, Kato S, Okamura R, Miller VA, Leyland-Jones B, Lippman SM, Kurzrock R. PMID: 32949172; PMCID: PMC7648352.
View in:
PubMed Mentions:
3 Fields:
Translation:
Humans
-
Survival Implications of the Relationship between Tissue versus Circulating Tumor DNA TP53 Mutations-A Perspective from a Real-World Precision Medicine Cohort. Mol Cancer Ther. 2020 12; 19(12):2612-2620.
Rosenberg S, Okamura R, Kato S, Soussi T, Kurzrock R. PMID: 32999047.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients. Mol Oncol. 2021 01; 15(1):67-79.
Charo LM, Eskander RN, Okamura R, Patel SP, Nikanjam M, Lanman RB, Piccioni DE, Kato S, McHale MT, Kurzrock R. PMID: 32881280; PMCID: PMC7782073.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Comprehensive genomic landscape and precision therapeutic approach in biliary tract cancers. Int J Cancer. 2021 02 01; 148(3):702-712.
Okamura R, Kurzrock R, Mallory RJ, Fanta PT, Burgoyne AM, Clary BM, Kato S, Sicklick JK. PMID: 32700810; PMCID: PMC7739197.
View in:
PubMed Mentions:
30 Fields:
Translation:
Humans
-
Letter responds to comment on "intention-to-treat analysis in precision oncology: A cautious interpretation". Eur J Cancer. 2020 10; 138:228.
Sicklick J, Kato S, Kurzrock R. PMID: 32839070.
View in:
PubMed Mentions: Fields:
Translation:
Humans
-
Therapeutic Implications of Epidermal Growth Factor Receptor (EGFR) in the Treatment of Metastatic Gastric/GEJ Cancer. Front Oncol. 2020; 10:1312.
Adashek JJ, Arroyo-Martinez Y, Menta AK, Kurzrock R, Kato S. PMID: 32850413; PMCID: PMC7418523.
View in:
PubMed Mentions:
9
-
High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers. Mol Cancer Ther. 2020 10; 19(10):2139-2145.
Riviere P, Goodman AM, Okamura R, Barkauskas DA, Whitchurch TJ, Lee S, Khalid N, Collier R, Mareboina M, Frampton GM, Fabrizio D, Sharabi AB, Kato S, Kurzrock R. PMID: 32747422; PMCID: PMC7541603.
View in:
PubMed Mentions:
37 Fields:
Translation:
Humans
-
Afebrile Pneumonia in a Patient With Multicentric Castleman Disease on Siltuximab: Infection Without Fever on Anti-Interleukin-6 Therapy. Cureus. 2020 Jul 02; 12(7):e8967.
Cohen PR, Nikanjam M, Kato S, Goodman AM, Kurzrock R. PMID: 32766009; PMCID: PMC7398726.
View in:
PubMed Mentions:
1
-
Transcriptomic silencing as a potential mechanism of treatment resistance. JCI Insight. 2020 06 04; 5(11).
Adashek JJ, Kato S, Parulkar R, Szeto CW, Sanborn JZ, Vaske CJ, Benz SC, Reddy SK, Kurzrock R. PMID: 32493840; PMCID: PMC7308055.
View in:
PubMed Mentions:
21 Fields:
Translation:
HumansCells
-
Repurposing Interleukin-6 Inhibitors to Combat COVID-19. J Immunother Precis Oncol. 2020; 3(2):52-55.
Kato S, Kurzrock R. PMID: 34169296; PMCID: PMC8221576.
View in:
PubMed Mentions:
6
-
MHC-I genotype and tumor mutational burden predict response to immunotherapy. Genome Med. 2020 05 19; 12(1):45.
Goodman AM, Castro A, Pyke RM, Okamura R, Kato S, Riviere P, Frampton G, Sokol E, Zhang X, Ball ED, Carter H, Kurzrock R. PMID: 32430031; PMCID: PMC7236948.
View in:
PubMed Mentions:
45 Fields:
Translation:
Humans
-
Precision oncology: the intention-to-treat analysis fallacy. Eur J Cancer. 2020 07; 133:25-28.
Sicklick JK, Kato S, Okamura R, Kurzrock R. PMID: 32422506; PMCID: PMC7786388.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
-
The paradox of cancer genes in non-malignant conditions: implications for precision medicine. Genome Med. 2020 02 17; 12(1):16.
Adashek JJ, Kato S, Lippman SM, Kurzrock R. PMID: 32066498; PMCID: PMC7027240.
View in:
PubMed Mentions:
11 Fields:
Translation:
HumansAnimals
-
ARID1A alterations function as a biomarker for longer progression-free survival after anti-PD-1/PD-L1 immunotherapy. J Immunother Cancer. 2020 02; 8(1).
Okamura R, Kato S, Lee S, Jimenez RE, Sicklick JK, Kurzrock R. PMID: 32111729; PMCID: PMC7057434.
View in:
PubMed Mentions:
72 Fields:
Translation:
Humans
-
Prognostic implications of RAS alterations in diverse malignancies and impact of targeted therapies. Int J Cancer. 2020 06 15; 146(12):3450-3460.
Kato S, Okamura R, Sicklick JK, Daniels GA, Hong DS, Goodman A, Weihe E, Lee S, Khalid N, Collier R, Mareboina M, Riviere P, Whitchurch TJ, Fanta PT, Lippman SM, Kurzrock R. PMID: 31782524; PMCID: PMC10200262.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
-
Clinical correlates of blood-derived circulating tumor DNA in pancreatic cancer. J Hematol Oncol. 2019 12 04; 12(1):130.
Patel H, Okamura R, Fanta P, Patel C, Lanman RB, Raymond VM, Kato S, Kurzrock R. PMID: 31801585; PMCID: PMC6894333.
View in:
PubMed Mentions:
42 Fields:
Translation:
Humans
-
Hyperprogression and Immune Checkpoint Inhibitors: Hype or Progress? Oncologist. 2020 02; 25(2):94-98.
Adashek JJ, Kato S, Ferrara R, Lo Russo G, Kurzrock R. PMID: 32043794; PMCID: PMC7011624.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
-
Genomic Profiling of Blood-Derived Circulating Tumor DNA from Patients with Colorectal Cancer: Implications for Response and Resistance to Targeted Therapeutics. Mol Cancer Ther. 2019 10; 18(10):1852-1862.
Choi IS, Kato S, Fanta PT, Leichman L, Okamura R, Raymond VM, Lanman RB, Lippman SM, Kurzrock R. PMID: 31320401.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Temporal and spatial effects and survival outcomes associated with concordance between tissue and blood KRAS alterations in the pan-cancer setting. Int J Cancer. 2020 01 15; 146(2):566-576.
Mardinian K, Okamura R, Kato S, Kurzrock R. PMID: 31199507; PMCID: PMC6874714.
View in:
PubMed Mentions:
13 Fields:
Translation:
Humans
-
Molecular Profiling of Tumor Tissue and Plasma Cell-Free DNA from Patients with Non-Langerhans Cell Histiocytosis. Mol Cancer Ther. 2019 06; 18(6):1149-1157.
Janku F, Diamond EL, Goodman AM, Raghavan VK, Barnes TG, Kato S, Abdel-Wahab O, Durham BH, Meric-Bernstam F, Kurzrock R. PMID: 31015311; PMCID: PMC6548628.
View in:
PubMed Mentions:
15 Fields:
Translation:
Humans
-
Molecular profiling of cancer patients enables personalized combination therapy: the I-PREDICT study. Nat Med. 2019 05; 25(5):744-750.
Sicklick JK, Kato S, Okamura R, Schwaederle M, Hahn ME, Williams CB, De P, Krie A, Piccioni DE, Miller VA, Ross JS, Benson A, Webster J, Stephens PJ, Lee JJ, Fanta PT, Lippman SM, Leyland-Jones B, Kurzrock R. PMID: 31011206; PMCID: PMC6553618.
View in:
PubMed Mentions:
245 Fields:
Translation:
HumansCTClinical Trials
-
Phenotypic and Genomic Determinants of Immunotherapy Response Associated with Squamousness. Cancer Immunol Res. 2019 06; 7(6):866-873.
Goodman AM, Kato S, Chattopadhyay R, Okamura R, Saunders IM, Montesion M, Frampton GM, Miller VA, Daniels GA, Kurzrock R. PMID: 31003990; PMCID: PMC6548620.
View in:
PubMed Mentions:
16 Fields:
Translation:
Humans
-
Genomic Assessment of Blood-Derived Circulating Tumor DNA in Patients With Colorectal Cancers: Correlation With Tissue Sequencing, Therapeutic Response, and Survival. JCO Precis Oncol. 2019; 3.
Kato S, Schwaederlé MC, Fanta PT, Okamura R, Leichman L, Lippman SM, Lanman RB, Raymond VM, Talasaz A, Kurzrock R. PMID: 31032472; PMCID: PMC6484865.
View in:
PubMed Mentions:
30 Fields:
-
Revisiting Epidermal Growth Factor Receptor (EGFR) Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With Advanced Malignancies. JCO Precis Oncol. 2019; 3.
Kato S, Okamura R, Mareboina M, Lee S, Goodman A, Patel SP, Fanta PT, Schwab RB, Vu P, Raymond VM, Lanman RB, Sicklick JK, Lippman SM, Kurzrock R. PMID: 31058253; PMCID: PMC6497417.
View in:
PubMed Mentions:
36 Fields:
-
Identification of targets for prostate cancer immunotherapy. Prostate. 2019 04; 79(5):498-505.
Papanicolau-Sengos A, Yang Y, Pabla S, Lenzo FL, Kato S, Kurzrock R, DePietro P, Nesline M, Conroy J, Glenn S, Chatta G, Morrison C. PMID: 30614027.
View in:
PubMed Mentions:
18 Fields:
Translation:
Humans
-
Genome-Wide Sequencing of Cell-Free DNA Identifies Copy-Number Alterations That Can Be Used for Monitoring Response to Immunotherapy in Cancer Patients. Mol Cancer Ther. 2019 02; 18(2):448-458.
Jensen TJ, Goodman AM, Kato S, Ellison CK, Daniels GA, Kim L, Nakashe P, McCarthy E, Mazloom AR, McLennan G, Grosu DS, Ehrich M, Kurzrock R. PMID: 30523049.
View in:
PubMed Mentions:
46 Fields:
Translation:
HumansCells
-
Analysis of NTRK Alterations in Pan-Cancer Adult and Pediatric Malignancies: Implications for NTRK-Targeted Therapeutics. JCO Precis Oncol. 2018; 2018.
Okamura R, Boichard A, Kato S, Sicklick JK, Bazhenova L, Kurzrock R. PMID: 30637364; PMCID: PMC6329466.
View in:
PubMed Mentions:
119 Fields:
-
An avatar for precision cancer therapy. Nat Biotechnol. 2018 11 09; 36(11):1053-1055.
Kato S, Kurzrock R. PMID: 30412185.
View in:
PubMed Mentions:
4 Fields:
Translation:
Humans
-
Phase 1 study of the combination of vemurafenib, carboplatin, and paclitaxel in patients with BRAF-mutated melanoma and other advanced malignancies. Cancer. 2019 02 01; 125(3):463-472.
Bhatty M, Kato S, Piha-Paul SA, Naing A, Subbiah V, Huang HJ, Karp DD, Tsimberidou AM, Zinner RG, Hwu WJ, Javle M, Patel SP, Hu MI, Varadhachary GR, Conley AP, Ramzanali NM, Holley VR, Kurzrock R, Meric-Bernstam F, Kwang Chae Y, Kim KB, Falchook GS, Janku F. PMID: 30383888; PMCID: PMC6340722.
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansCTClinical Trials
-
Analysis of Circulating Tumor DNA and Clinical Correlates in Patients with Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma. Clin Cancer Res. 2018 12 15; 24(24):6248-6256.
Kato S, Okamura R, Baumgartner JM, Patel H, Leichman L, Kelly K, Sicklick JK, Fanta PT, Lippman SM, Kurzrock R. PMID: 30348637; PMCID: PMC6384095.
View in:
PubMed Mentions:
61 Fields:
Translation:
Humans
-
Prevalence of PDL1 Amplification and Preliminary Response to Immune Checkpoint Blockade in Solid Tumors. JAMA Oncol. 2018 09 01; 4(9):1237-1244.
Goodman AM, Piccioni D, Kato S, Boichard A, Wang HY, Frampton G, Lippman SM, Connelly C, Fabrizio D, Miller V, Sicklick JK, Kurzrock R. PMID: 29902298; PMCID: PMC6139049.
View in:
PubMed Mentions:
133 Fields:
Translation:
Humans
-
JAK2 V617F mutation in plasma cell-free DNA preceding clinically overt myelofibrosis: Implications for early diagnosis. Cancer Biol Ther. 2018 08 03; 19(8):664-668.
Choi MY, Kato S, Wang HY, Lin JH, Lanman RB, Kurzrock R. PMID: 29565699; PMCID: PMC6067874.
View in:
PubMed Mentions:
2 Fields:
Translation:
Humans
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Analysis of MDM2 Amplification: Next-Generation Sequencing of Patients With Diverse Malignancies. JCO Precis Oncol. 2018; 2018.
Kato S, Ross JS, Gay L, Dayyani F, Roszik J, Subbiah V, Kurzrock R. PMID: 30148248; PMCID: PMC6106866.
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PubMed Mentions:
32 Fields:
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Phase I study of nab-paclitaxel, gemcitabine, and bevacizumab in patients with advanced cancers. Br J Cancer. 2018 05; 118(11):1419-1424.
Sen S, Kato S, Agarwal R, Piha-Paul S, Hess K, Karp D, Janku F, Fu S, Naing A, Pant S, Falchook G, Tang C, Wu X, Ye Y, Tsimberidou A, Subbiah V, Kurzrock R, Byers L, Westin S, Lim J, Bean S, Bass A, Nguyen L, Meric-Bernstam F, Hong D. PMID: 29695765; PMCID: PMC5988803.
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PubMed Mentions:
4 Fields:
Translation:
HumansCTClinical Trials
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Razelle Kurzrock and Shumei Kato on Immunotherapy and Hyperprogression of Disease. Oncology (Williston Park). 2018 04 15; 32(4):150-1, 163.
Kurzrock R, Kato S. PMID: 29684227.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Genomic landscape of advanced basal cell carcinoma: Implications for precision treatment with targeted and immune therapies. Oncoimmunology. 2018; 7(3):e1404217.
Goodman AM, Kato S, Cohen PR, Boichard A, Frampton G, Miller V, Stephens PJ, Daniels GA, Kurzrock R. PMID: 29399405; PMCID: PMC5790366.
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PubMed Mentions:
29 Fields:
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Phase I study of the combination of crizotinib (as a MET inhibitor) and dasatinib (as a c-SRC inhibitor) in patients with advanced cancer. Invest New Drugs. 2018 06; 36(3):416-423.
Kato S, Jardim DL, Johnson FM, Subbiah V, Piha-Paul S, Tsimberidou AM, Falchook GS, Karp D, Zinner R, Wheler J, Janku F, Fu S, Lim J, Bean S, Nguyen L, Urban S, Browne E, Meric-Bernstam F, Hong DS. PMID: 29047029; PMCID: PMC5908757.
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PubMed Mentions:
12 Fields:
Translation:
HumansCTClinical Trials
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Rare Tumor Clinic: The University of California San Diego Moores Cancer Center Experience with a Precision Therapy Approach. Oncologist. 2018 02; 23(2):171-178.
Kato S, Kurasaki K, Ikeda S, Kurzrock R. PMID: 29038235; PMCID: PMC5813742.
View in:
PubMed Mentions:
24 Fields:
Translation:
Humans
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Genomics of Immunotherapy-Associated Hyperprogressors-Response. Clin Cancer Res. 2017 10 15; 23(20):6376.
Kato S, Kurzrock R. PMID: 29030333.
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PubMed Mentions:
6 Fields:
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Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. Cancer Discov. 2017 12; 7(12):1464-1479.
Seguin L, Camargo MF, Wettersten HI, Kato S, Desgrosellier JS, von Schalscha T, Elliott KC, Cosset E, Lesperance J, Weis SM, Cheresh DA. PMID: 28893801; PMCID: PMC5718959.
View in:
PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers. Mol Cancer Ther. 2017 11; 16(11):2598-2608.
Goodman AM, Kato S, Bazhenova L, Patel SP, Frampton GM, Miller V, Stephens PJ, Daniels GA, Kurzrock R. PMID: 28835386; PMCID: PMC5670009.
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PubMed Mentions:
1095 Fields:
Translation:
HumansAnimalsCells
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Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing. Cancer Res. 2017 10 01; 77(19):5419-5427.
Schwaederle M, Chattopadhyay R, Kato S, Fanta PT, Banks KC, Choi IS, Piccioni DE, Ikeda S, Talasaz A, Lanman RB, Bazhenova L, Kurzrock R. PMID: 28807936; PMCID: PMC5626633.
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PubMed Mentions:
59 Fields:
Translation:
Humans
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Appearance of New Cutaneous Superficial Basal Cell Carcinomas during Successful Nivolumab Treatment of Refractory Metastatic Disease: Implications for Immunotherapy in Early Versus Late Disease. Int J Mol Sci. 2017 Jul 31; 18(8).
Cohen PR, Kato S, Goodman AM, Ikeda S, Kurzrock R. PMID: 28788102; PMCID: PMC5578053.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Insurance Clearance for Early-Phase Oncology Clinical Trials Following the Affordable Care Act. Clin Cancer Res. 2017 Aug 01; 23(15):4155-4162.
Kehl KL, Fullmer CP, Fu S, George GC, Hess KR, Janku F, Karp DD, Kato S, Kizer CK, Kurzrock R, Naing A, Pant S, Piha-Paul SA, Subbiah V, Tsimberidou AM, Hong DS. PMID: 28729355; PMCID: PMC5902668.
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PubMed Mentions:
2 Fields:
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Counterpoint: Successes in the Pursuit of Precision Medicine: Biomarkers Take Credit. J Natl Compr Canc Netw. 2017 07; 15(7):863-866.
Kato S, Subbiah V, Kurzrock R. PMID: 28687573; PMCID: PMC6317845.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Utility of Genomic Analysis In Circulating Tumor DNA from Patients with Carcinoma of Unknown Primary. Cancer Res. 2017 08 15; 77(16):4238-4246.
Kato S, Krishnamurthy N, Banks KC, De P, Williams K, Williams C, Leyland-Jones B, Lippman SM, Lanman RB, Kurzrock R. PMID: 28642281; PMCID: PMC5729906.
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PubMed Mentions:
63 Fields:
Translation:
Humans
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Exceptional Response to Nivolumab and Stereotactic Body Radiation Therapy (SBRT) in Neuroendocrine Cervical Carcinoma with High Tumor Mutational Burden: Management Considerations from the Center For Personalized Cancer Therapy at UC San Diego Moores Cancer Center. Oncologist. 2017 06; 22(6):631-637.
Sharabi A, Kim SS, Kato S, Sanders PD, Patel SP, Sanghvi P, Weihe E, Kurzrock R. PMID: 28550027; PMCID: PMC5469598.
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PubMed Mentions:
51 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
439 Fields:
Translation:
Humans
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RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients. Clin Cancer Res. 2017 04 15; 23(8):1988-1997.
Kato S, Subbiah V, Marchlik E, Elkin SK, Carter JL, Kurzrock R. PMID: 27683183.
View in:
PubMed Mentions:
91 Fields:
Translation:
Humans
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Genomic Landscape of Malignant Mesotheliomas. Mol Cancer Ther. 2016 10; 15(10):2498-2507.
Kato S, Tomson BN, Buys TP, Elkin SK, Carter JL, Kurzrock R. PMID: 27507853.
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PubMed Mentions:
31 Fields:
Translation:
Humans
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Cell-Cycle Gene Alterations in 4,864 Tumors Analyzed by Next-Generation Sequencing: Implications for Targeted Therapeutics. Mol Cancer Ther. 2016 07; 15(7):1682-90.
Helsten T, Kato S, Schwaederle M, Tomson BN, Buys TP, Elkin SK, Carter JL, Kurzrock R. PMID: 27196769.
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PubMed Mentions:
20 Fields:
Translation:
Humans
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The Conundrum of Genetic "Drivers" in Benign Conditions. J Natl Cancer Inst. 2016 08; 108(8).
Kato S, Lippman SM, Flaherty KT, Kurzrock R. PMID: 27059373; PMCID: PMC5017937.
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PubMed Mentions:
54 Fields:
Translation:
Humans
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Personalized comprehensive molecular profiling of high risk osteosarcoma: Implications and limitations for precision medicine. Oncotarget. 2015 Dec 01; 6(38):40642-54.
Subbiah V, Wagner MJ, McGuire MF, Sarwari NM, Devarajan E, Lewis VO, Westin S, Kato S, Brown RE, Anderson P. PMID: 26510912; PMCID: PMC4747358.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
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Genomic landscape of salivary gland tumors. Oncotarget. 2015 Sep 22; 6(28):25631-45.
Kato S, Elkin SK, Schwaederle M, Tomson BN, Helsten T, Carter JL, Kurzrock R. PMID: 26247885; PMCID: PMC4694855.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansCells
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A window-of-opportunity biomarker study of etodolac in resectable breast cancer. Cancer Med. 2015 Oct; 4(10):1583-8.
Schwab RB, Kato S, Crain B, Pu M, Messer K, Weidner N, Blair SL, Wallace AM, Carson DA, Parker BA. PMID: 26275572; PMCID: PMC4618628.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Clinical next-generation sequencing reveals aggressive cancer biology in adolescent and young adult patients. Oncoscience. 2015; 2(7):646-58.
Subbiah V, Bupathi M, Kato S, Livingston A, Slopis J, Anderson PM, Hong DS. PMID: 26328274; PMCID: PMC4549362.
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PubMed Mentions:
4
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Challenges and perspective of drug repurposing strategies in early phase clinical trials. Oncoscience. 2015; 2(6):576-80.
Kato S, Moulder SL, Ueno NT, Wheler JJ, Meric-Bernstam F, Kurzrock R, Janku F. PMID: 26244164; PMCID: PMC4506360.
View in:
PubMed Mentions:
15
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Cell-free DNA as a novel marker in cancer therapy. Biomark Med. 2015; 9(7):703-12.
Kato S, Janku F. PMID: 26174844.
View in:
PubMed Mentions:
11 Fields:
Translation:
Humans
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Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics. Cell Cycle. 2015; 14(8):1252-9.
Kato S, Schwaederle M, Daniels GA, Piccioni D, Kesari S, Bazhenova L, Shimabukuro K, Parker BA, Fanta P, Kurzrock R. PMID: 25695927; PMCID: PMC4614867.
View in:
PubMed Mentions:
25 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
55 Fields:
Translation:
HumansAnimalsCells
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An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. Nat Cell Biol. 2014 May; 16(5):457-68.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S, Weis SM, Cheresh DA. PMID: 24747441; PMCID: PMC4105198.
View in:
PubMed Mentions:
208 Fields:
Translation:
HumansAnimalsCells
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EGFR-mediated carcinoma cell metastasis mediated by integrin αvβ5 depends on activation of c-Src and cleavage of MUC1. PLoS One. 2012; 7(5):e36753.
Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. PMID: 22586492; PMCID: PMC3346745.
View in:
PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells