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Kyriacos Nicolaou

TitleEmeritus Professor
InstitutionUniversity of California San Diego
DepartmentChemistry and Biochemistry
Address9500 Gilman Drive #0358
La Jolla CA 92093
Phone858-784-2400
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Nicolaou K, Rigol S. A brief history of antibiotics and select advances in their synthesis. J Antibiot (Tokyo). 2018 Feb; 71(2):153-184. PMID: 28676714.
      View in: PubMed
    2. Nicolaou K, Vourloumis D, Totokotsopoulos S, Papakyriakou A, Karsunky H, Fernando H, Gavrilyuk J, Webb D, Stepan AF. Synthesis and Biopharmaceutical Evaluation of Imatinib Analogues Featuring Unusual Structural Motifs. ChemMedChem. 2016 Jan 05; 11(1):31-7. PMID: 26585829.
      View in: PubMed
    3. Nicolaou K, Valiulin RA. Synthesis and biological evaluation of new paclitaxel analogs and discovery of potent antitumor agents. Org Biomol Chem. 2013 Jul 07; 11(25):4154-63. PMID: 23685867; PMCID: PMC3712363.
    4. Koppaka V, Thompson DC, Chen Y, Ellermann M, Nicolaou K, Juvonen RO, Petersen D, Deitrich RA, Hurley TD, Vasiliou V. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application. Pharmacol Rev. 2012 Jul; 64(3):520-39. PMID: 22544865; PMCID: PMC3400832.
    5. Cao Z, LePage KT, Frederick MO, Nicolaou K, Murray TF. Involvement of caspase activation in azaspiracid-induced neurotoxicity in neocortical neurons. Toxicol Sci. 2010 Apr; 114(2):323-34. PMID: 20047973; PMCID: PMC2840215.
    6. Starosta AL, Qin H, Mikolajka A, Leung GY, Schwinghammer K, Nicolaou K, Chen DY, Cooperman BS, Wilson DN. Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays. Chem Biol. 2009 Oct 30; 16(10):1087-96. PMID: 19875082; PMCID: PMC3117328.
    7. Vale C, Nicolaou K, Frederick MO, Vieytes MR, Botana LM. Cell volume decrease as a link between azaspiracid-induced cytotoxicity and c-Jun-N-terminal kinase activation in cultured neurons. Toxicol Sci. 2010 Jan; 113(1):158-68. PMID: 19815690; PMCID: PMC2794333.
    8. Wrasidlo W, Gaedicke G, Guy RK, Renaud J, Pitsinos E, Nicolaou K, Reisfeld RA, Lode HN. A novel 2'-(N-methylpyridinium acetate) prodrug of paclitaxel induces superior antitumor responses in preclinical cancer models. Bioconjug Chem. 2002 Sep-Oct; 13(5):1093-9. PMID: 12236791.
      View in: PubMed
    9. Giannakakou P, Nakano M, Nicolaou K, O'Brate A, Yu J, Blagosklonny MV, Greber UF, Fojo T. Enhanced microtubule-dependent trafficking and p53 nuclear accumulation by suppression of microtubule dynamics. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10855-60. PMID: 12145320; PMCID: PMC125062.