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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts. BMC Med Genomics. 2024 Sep 27; 17(1):235.
Wani AH, Katrinli S, Zhao X, Daskalakis NP, Zannas AS, Aiello AE, Baker DG, Boks MP, Brick LA, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes JP, Kessler RC, King AP, Koen N, Liberzon I, Lori A, Luykx JJ, Maihofer AX, Milberg W, Miller MW, Mufford MS, Nugent NR, Rauch S, Ressler KJ, Risbrough VB, Rutten BPF, Stein DJ, Stein MB, Ursano RJ, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Nievergelt CM, Logue MW, Smith AK, Uddin M. PMID: 39334086; PMCID: PMC11429352.
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HumansCells
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Sex-Specific Effects of Early Life Unpredictability on Hippocampal and Amygdala Responses to Novelty in Adolescents. bioRxiv. 2024 Sep 21.
Davis EP, Leonard BT, Jirsaraie RJ, Keator DB, Small SL, Sandman CA, Risbrough VB, Stern HS, Glynn LM, Yassa MA, Baram TZ, Rasmussen JM. PMID: 39345394; PMCID: PMC11429980.
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The Relationship between REM Sleep Prior to Analogue Trauma and Intrusive Memories. Sleep. 2024 Sep 05.
Alkalame L, Ogden J, Clark JW, Porcheret K, Risbrough VB, Drummond SPA. PMID: 39235362.
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Epigenome-wide association studies identify novel DNA methylation sites associated with PTSD: A meta-analysis of 23 military and civilian cohorts. medRxiv. 2024 Jul 15.
Katrinli S, Wani AH, Maihofer AX, Ratanatharathorn A, Daskalakis NP, Montalvo-Ortiz J, Núñez-Ríos DL, Zannas AS, Zhao X, Aiello AE, Ashley-Koch AE, Avetyan D, Baker DG, Beckham JC, Boks MP, Brick LA, Bromet E, Champagne FA, Chen CY, Dalvie S, Dennis MF, Fatumo S, Fortier C, Galea S, Garrett ME, Geuze E, Grant G, Hayes JP, Hemmings SM, Huber BR, Jajoo A, Jansen S, Kessler RC, Kimbrel NA, King AP, Kleinman JE, Koen N, Koenen KC, Kuan PF, Liberzon I, Linnstaedt SD, Lori A, Luft BJ, Luykx JJ, Marx CE, McLean SA, Mehta D, Milberg W, Miller MW, Mufford MS, Musanabaganwa C, Mutabaruka J, Mutesa L, Nemeroff CB, Nugent NR, Orcutt HK, Qin XJ, Rauch SAM, Ressler KJ, Risbrough VB, Rutembesa E, Rutten BPF, Seedat S, Stein DJ, Stein MB, Toikumo S, Ursano RJ, Uwineza A, Verfaellie MH, Vermetten E, Vinkers CH, Ware EB, Wildman DE, Wolf EJ, Young RM, Zhao Y, van den Heuvel LL, PGC-PTSD Epigenetics Workgroup, PsychENCODE PTSD Brainomics Project, Traumatic Stress Brain Research, Uddin M, Nievergelt CM, Smith AK, Logue MW. PMID: 39072012; PMCID: PMC11275670.
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Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder. Transl Psychiatry. 2024 Apr 27; 14(1):199.
Burrows K, Figueroa-Hall LK, Stewart JL, Alarbi AM, Kuplicki R, Hannafon BN, Tan C, Risbrough VB, McKinney BA, Ramesh R, Victor TA, Aupperle R, Savitz J, Teague TK, Khalsa SS, Paulus MP. PMID: 38678012; PMCID: PMC11055873.
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PubMed Mentions:
1 Fields:
Translation:
HumansCells
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Genome-wide association analyses identify 95 risk loci and provide insights into the neurobiology of post-traumatic stress disorder. Nat Genet. 2024 May; 56(5):792-808.
Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babic D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenovic AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goleva SB, Gordon SD, Goçi A, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SMJ, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljevic M, Javanbakht A, Jenkins GD, Johnson J, Jones I, Jovanovic T, Karstoft KI, Kaufman ML, Kennedy JL, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kotov R, Kranzler HR, Krebs K, Kremen WS, Kuan PF, Lawford BR, Lebois LAM, Lehto K, Levey DF, Lewis C, Liberzon I, Linnstaedt SD, Logue MW, Lori A, Lu Y, Luft BJ, Lupton MK, Luykx JJ, Makotkine I, Maples-Keller JL, Marchese S, Marmar C, Martin NG, Martínez-Levy GA, McAloney K, McFarlane A, McLaughlin KA, McLean SA, Medland SE, Mehta D, Meyers J, Michopoulos V, Mikita EA, Milani L, Milberg W, Miller MW, Morey RA, Morris CP, Mors O, Mortensen PB, Mufford MS, Nelson EC, Nordentoft M, Norman SB, Nugent NR, O'Donnell M, Orcutt HK, Pan PM, Panizzon MS, Pathak GA, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Porjesz B, Powers A, Qin XJ, Ratanatharathorn A, Risbrough VB, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero KJ, Rung A, Runz H, Rutten BPF, de Viteri SS, Salum GA, Sampson L, Sanchez SE, Santoro M, Seah C, Seedat S, Seng JS, Shabalin A, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stensland S, Stevens JS, Sumner JA, Teicher MH, Thompson WK, Tiwari AK, Trapido E, Uddin M, Ursano RJ, Valdimarsdóttir U, Van Hooff M, Vermetten E, Vinkers CH, Voisey J, Wang Y, Wang Z, Waszczuk M, Weber H, Wendt FR, Werge T, Williams MA, Williamson DE, Winsvold BS, Winternitz S, Wolf C, Wolf EJ, Xia Y, Xiong Y, Yehuda R, Young KA, Young RM, Zai CC, Zai GC, Zervas M, Zhao H, Zoellner LA, Zwart JA, deRoon-Cassini T, van Rooij SJH, van den Heuvel LL, AURORA Study, Estonian Biobank Research Team, FinnGen Investigators, HUNT All-In Psychiatry, Stein MB, Ressler KJ, Koenen KC. PMID: 38637617; PMCID: PMC11396662.
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6 Fields:
Translation:
Humans
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A Novel Simple ImmunoAssay for Quantification of Blood Anti-NMDAR1 Autoantibodies. bioRxiv. 2024 Apr 15.
Vaughn M, Powell S, Risbrough V, Zhou X. PMID: 38659751; PMCID: PMC11042199.
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Reframing and refining model system validity for anxiety and depression research: A commentary on Gencturk & Unal (2024). Cogn Affect Behav Neurosci. 2024 Apr; 24(2):225-227.
Flandreau E, Risbrough V. PMID: 38453806.
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Humans
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Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts. Res Sq. 2024 Feb 15.
Wani A, Katrinli S, Zhao X, Daskalakis N, Zannas A, Aiello A, Baker D, Boks M, Brick L, Chen CY, Dalvie S, Fortier C, Geuze E, Hayes J, Kessler R, King A, Koen N, Liberzon I, Lori A, Luykx J, Maihofer A, Milberg W, Miller M, Mufford M, Nugent N, Rauch S, Ressler K, Risbrough V, Rutten B, Stein D, Stein M, Ursano R, Verfaellie M, Ware E, Wildman D, Wolf E, Nievergelt C, Logue M, Smith A, Uddin M, Vermetten E, Vinkers C. PMID: 38410438; PMCID: PMC10896387.
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High executive functioning is associated with reduced posttraumatic stress after trauma exposure among male U.S. military personnel. Front Psychol. 2023; 14:1181055.
Liu SR, Moore TM, Gur RC, Nievergelt C, Baker DG, Risbrough V, Acheson DT. PMID: 37818418; PMCID: PMC10560729.
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Discovery of 95 PTSD loci provides insight into genetic architecture and neurobiology of trauma and stress-related disorders. medRxiv. 2023 Sep 02.
Nievergelt CM, Maihofer AX, Atkinson EG, Chen CY, Choi KW, Coleman JR, Daskalakis NP, Duncan LE, Polimanti R, Aaronson C, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegoviç E, Babic D, Bacanu SA, Baker DG, Batzler A, Beckham JC, Belangero S, Benjet C, Bergner C, Bierer LM, Biernacka JM, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Brandolino A, Breen G, Bressan RA, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Bækvad-Hansen M, Børglum AD, Børte S, Cahn L, Calabrese JR, Caldas-de-Almeida JM, Chatzinakos C, Cheema S, Clouston SAP, Colodro-Conde L, Coombes BJ, Cruz-Fuentes CS, Dale AM, Dalvie S, Davis LK, Deckert J, Delahanty DL, Dennis MF, deRoon-Cassini T, Desarnaud F, DiPietro CP, Disner SG, Docherty AR, Domschke K, Dyb G, Kulenovic AD, Edenberg HJ, Evans A, Fabbri C, Fani N, Farrer LA, Feder A, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goci A, Goleva SB, Gordon SD, Grasser LR, Guindalini C, Haas M, Hagenaars S, Hauser MA, Heath AC, Hemmings SM, Hesselbrock V, Hickie IB, Hogan K, Hougaard DM, Huang H, Huckins LM, Hveem K, Jakovljevic M, Javanbakht A, Jenkins GD, Johnson J, Jones I, Jovanovic T, Karstoft KI, Kaufman ML, Kennedy JL, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kotov R, Kranzler HR, Krebs K, Kremen WS, Kuan PF, Lawford BR, Lebois LAM, Lehto K, Levey DF, Lewis C, Liberzon I, Linnstaedt SD, Logue MW, Lori A, Lu Y, Luft BJ, Lupton MK, Luykx JJ, Makotkine I, Maples-Keller JL, Marchese S, Marmar C, Martin NG, MartÍnez-Levy GA, McAloney K, McFarlane A, McLaughlin KA, McLean SA, Medland SE, Mehta D, Meyers J, Michopoulos V, Mikita EA, Milani L, Milberg W, Miller MW, Morey RA, Morris CP, Mors O, Mortensen PB, Mufford MS, Nelson EC, Nordentoft M, Norman SB, Nugent NR, O'Donnell M, Orcutt HK, Pan PM, Panizzon MS, Pathak GA, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Porjesz B, Powers A, Qin XJ, Ratanatharathorn A, Risbrough VB, Roberts AL, Rothbaum BO, Rothbaum AO, Roy-Byrne P, Ruggiero KJ, Rung A, Runz H, Rutten BPF, de Viteri SS, Salum GA, Sampson L, Sanchez SE, Santoro M, Seah C, Seedat S, Seng JS, Shabalin A, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stensland S, Stevens JS, Sumner JA, Teicher MH, Thompson WK, Tiwari AK, Trapido E, Uddin M, Ursano RJ, Valdimarsdóttir U, van den Heuvel LL, Van Hooff M, van Rooij SJ, Vermetten E, Vinkers CH, Voisey J, Wang Z, Wang Y, Waszczuk M, Weber H, Wendt FR, Werge T, Williams MA, Williamson DE, Winsvold BS, Winternitz S, Wolf EJ, Wolf C, Xia Y, Xiong Y, Yehuda R, Young RM, Young KA, Zai CC, Zai GC, Zervas M, Zhao H, Zoellner LA, Zwart JA, Stein MB, Ressler KJ, Koenen KC. PMID: 37693460; PMCID: PMC10491375.
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Nothing Ventured, Nothing Gained: Understanding Reward Circuit Mechanisms of Posttraumatic Stress Disorder. Biol Psychiatry Cogn Neurosci Neuroimaging. 2023 09; 8(9):877-879.
Stout DM, Risbrough VB. PMID: 37678965.
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Humans
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Protocol for a randomized controlled study examining the role of rapid eye movement sleep in fear-related mechanisms: rapid eye movement fragmentation and fear inhibition in adults with insomnia disorders before and after cognitive behavioral therapy for insomnia. Sleep Adv. 2023; 4(1):zpad030.
Vuong V, Mellor A, Risbrough VB, Bei B, Drummond SPA. PMID: 37663035; PMCID: PMC10474912.
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Exploring the role of neuronal-enriched extracellular vesicle miR-93 and interoception in major depressive disorder. Res Sq. 2023 Jun 16.
Burrows K, Figueroa-Hall L, Stewart J, Alarbi A, Kuplicki R, Hannafon B, Tan C, Risbrough V, McKinney B, Ramesh R, Victor T, Aupperle R, Savitz J, Teague K, Khalsa S, Paulus M. PMID: 37398092; PMCID: PMC10312986.
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Effects of total sleep deprivation on sensorimotor gating in humans. Behav Brain Res. 2023 07 09; 449:114487.
Vizeli P, Cuccurazzu B, Drummond SPA, Acheson DT, Risbrough VB. PMID: 37169130.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimals
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Association between inflammation, reward processing, and ibuprofen-induced increases of miR-23b in astrocyte-enriched extracellular vesicles: A randomized, placebo-controlled, double-blind, exploratory trial in healthy individuals. Brain Behav Immun Health. 2023 Feb; 27:100582.
Burrows K, Figueroa-Hall LK, Alarbi AM, Stewart JL, Kuplicki R, Tan C, Hannafon BN, Ramesh R, Savitz J, Khalsa S, Teague TK, Risbrough VB, Paulus MP. PMID: 36605933; PMCID: PMC9807827.
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PubMed Mentions:
2
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Development and application of novel performance validity metrics for computerized neurocognitive batteries. J Int Neuropsychol Soc. 2023 10; 29(8):789-797.
Scott JC, Moore TM, Roalf DR, Satterthwaite TD, Wolf DH, Port AM, Butler ER, Ruparel K, Nievergelt CM, Risbrough VB, Baker DG, Gur RE, Gur RC. PMID: 36503573; PMCID: PMC10258222.
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4 Fields:
Translation:
Humans
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PubMed Mentions: Fields:
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Exposure to unpredictability and mental health: Validation of the brief version of the Questionnaire of Unpredictability in Childhood (QUIC-5) in English and Spanish. Front Psychol. 2022; 13:971350.
Lindert NG, Maxwell MY, Liu SR, Stern HS, Baram TZ, Poggi Davis E, Risbrough VB, Baker DG, Nievergelt CM, Glynn LM. PMID: 36438371; PMCID: PMC9682115.
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PubMed Mentions:
8
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Pre-deployment threat learning predicts increased risk for post-deployment insomnia: Evidence from the Marine Resiliency Study. Behav Res Ther. 2022 12; 159:104223.
Hunt C, Stout DM, Tie Z, Acheson D, Colvonen PJ, Nievergelt CM, Yurgil KA, Baker DG, Risbrough VB. PMID: 36327523; PMCID: PMC9893737.
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2 Fields:
Translation:
Humans
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Prospective longitudinal assessment of sensorimotor gating as a risk/resiliency factor for posttraumatic stress disorder. Neuropsychopharmacology. 2022 12; 47(13):2238-2244.
Acheson DT, Baker DG, Nievergelt CM, Yurgil KA, Geyer MA, Risbrough VB. PMID: 36192631; PMCID: PMC9630259.
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Rare copy number variation in posttraumatic stress disorder. Mol Psychiatry. 2022 12; 27(12):5062-5069.
Maihofer AX, Engchuan W, Huguet G, Klein M, MacDonald JR, Shanta O, Thiruvahindrapuram B, Jean-Louis M, Saci Z, Jacquemont S, Scherer SW, Ketema E, Aiello AE, Amstadter AB, Avdibegovic E, Babic D, Baker DG, Bisson JI, Boks MP, Bolger EA, Bryant RA, Bustamante AC, Caldas-de-Almeida JM, Cardoso G, Deckert J, Delahanty DL, Domschke K, Dunlop BW, Dzubur-Kulenovic A, Evans A, Feeny NC, Franz CE, Gautam A, Geuze E, Goci A, Hammamieh R, Jakovljevic M, Jett M, Jones I, Kaufman ML, Kessler RC, King AP, Kremen WS, Lawford BR, Lebois LAM, Lewis C, Liberzon I, Linnstaedt SD, Lugonja B, Luykx JJ, Lyons MJ, Mavissakalian MR, McLaughlin KA, McLean SA, Mehta D, Mellor R, Morris CP, Muhie S, Orcutt HK, Peverill M, Ratanatharathorn A, Risbrough VB, Rizzo A, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero KJ, Rutten BPF, Schijven D, Seng JS, Sheerin CM, Sorenson MA, Teicher MH, Uddin M, Ursano RJ, Vinkers CH, Voisey J, Weber H, Winternitz S, Xavier M, Yang R, McD Young R, Zoellner LA, Psychiatric Genomics Consortium PTSD Working Group, Psychiatric Genomics Consortium CNV Working Group, Salem RM, Shaffer RA, Wu T, Ressler KJ, Stein MB, Koenen KC, Sebat J, Nievergelt CM. PMID: 36131047; PMCID: PMC9763110.
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1 Fields:
Translation:
Humans
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimals
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Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects. Front Pharmacol. 2022; 13:906639.
Vizeli P, Straumann I, Duthaler U, Varghese N, Eckert A, Paulus MP, Risbrough V, Liechti ME. PMID: 35910354; PMCID: PMC9326355.
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13
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Effects of modafinil on electroencephalographic microstates in healthy adults. Psychopharmacology (Berl). 2022 Aug; 239(8):2573-2584.
Linton SR, Murphy M, Schroder HS, Breiger M, Iturra-Mena AM, Kangas BD, Bergman J, Carlezon WA, Risbrough VB, Barnes SA, Der-Avakian A, Pizzagalli DA. PMID: 35471613; PMCID: PMC9296596.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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PubMed Mentions:
1 Fields:
Translation:
Humans
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Developing Biomarkers of Mild Traumatic Brain Injury: Promise and Progress of CNS-Derived Exosomes. Front Neurol. 2021; 12:698206.
Vaughn MN, Winston CN, Levin N, Rissman RA, Risbrough VB. PMID: 35222223; PMCID: PMC8866179.
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PubMed Mentions:
10
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Prospective examination of pre-trauma anhedonia as a risk factor for post-traumatic stress symptoms. Eur J Psychotraumatol. 2022; 13(1):2015949.
Acheson DT, Vinograd M, Nievergelt CM, Yurgil KA, Moore TM, Risbrough VB, Baker DG. PMID: 35070161; PMCID: PMC8774051.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Neuronally-enriched exosomal microRNA-27b mediates acute effects of ibuprofen on reward-related brain activity in healthy adults: a randomized, placebo-controlled, double-blind trial. Sci Rep. 2022 01 17; 12(1):861.
Burrows K, Figueroa-Hall LK, Kuplicki R, Stewart JL, Alarbi AM, Ramesh R, Savitz JB, Teague TK, Risbrough VB, Paulus MP. PMID: 35039595; PMCID: PMC8764091.
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PubMed Mentions:
4 Fields:
Translation:
Humans
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Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and oxidative stress. Mol Psychiatry. 2022 03; 27(3):1720-1728.
Katrinli S, Maihofer AX, Wani AH, Pfeiffer JR, Ketema E, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Kessler RC, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Logue MW, Nievergelt CM, Smith AK, Uddin M. PMID: 34992238; PMCID: PMC9106882.
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PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Anhedonia in Posttraumatic Stress Disorder: Prevalence, Phenotypes, and Neural Circuitry. Curr Top Behav Neurosci. 2022; 58:185-199.
Vinograd M, Stout DM, Risbrough VB. PMID: 34907507.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Role of Inflammation in Traumatic Brain Injury-Associated Risk for Neuropsychiatric Disorders: State of the Evidence and Where Do We Go From Here. Biol Psychiatry. 2022 03 01; 91(5):438-448.
Risbrough VB, Vaughn MN, Friend SF. PMID: 34955170.
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17 Fields:
Translation:
Humans
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Posttraumatic Stress Disorder and Cardiovascular Disease: State of the Science, Knowledge Gaps, and Research Opportunities. JAMA Cardiol. 2021 10 01; 6(10):1207-1216.
O'Donnell CJ, Schwartz Longacre L, Cohen BE, Fayad ZA, Gillespie CF, Liberzon I, Pathak GA, Polimanti R, Risbrough V, Ursano RJ, Vander Heide RS, Yancy CW, Vaccarino V, Sopko G, Stein MB. PMID: 34259831.
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PubMed Mentions:
48 Fields:
Translation:
Humans
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Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information. Biol Psychiatry. 2022 04 01; 91(7):626-636.
Maihofer AX, Choi KW, Coleman JRI, Daskalakis NP, Denckla CA, Ketema E, Morey RA, Polimanti R, Ratanatharathorn A, Torres K, Wingo AP, Zai CC, Aiello AE, Almli LM, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegovic E, Borglum AD, Babic D, Bækvad-Hansen M, Baker DG, Beckham JC, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Bradley B, Brashear M, Breen G, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Calabrese JR, Caldas-de-Almeida JM, Chen CY, Dale AM, Dalvie S, Deckert J, Delahanty DL, Dennis MF, Disner SG, Domschke K, Duncan LE, Džubur Kulenovic A, Erbes CR, Evans A, Farrer LA, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gautam A, Gelaye B, Gelernter J, Geuze E, Gillespie CF, Goçi A, Gordon SD, Guffanti G, Hammamieh R, Hauser MA, Heath AC, Hemmings SMJ, Hougaard DM, Jakovljevic M, Jett M, Johnson EO, Jones I, Jovanovic T, Qin XJ, Karstoft KI, Kaufman ML, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kranzler HR, Kremen WS, Lawford BR, Lebois LAM, Lewis C, Liberzon I, Linnstaedt SD, Logue MW, Lori A, Lugonja B, Luykx JJ, Lyons MJ, Maples-Keller JL, Marmar C, Martin NG, Maurer D, Mavissakalian MR, McFarlane A, McGlinchey RE, McLaughlin KA, McLean SA, Mehta D, Mellor R, Michopoulos V, Milberg W, Miller MW, Morris CP, Mors O, Mortensen PB, Nelson EC, Nordentoft M, Norman SB, O'Donnell M, Orcutt HK, Panizzon MS, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Rice JP, Risbrough VB, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero KJ, Rung A, Rutten BPF, Saccone NL, Sanchez SE, Schijven D, Seedat S, Seligowski AV, Seng JS, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stevens JS, Teicher MH, Thompson WK, Trapido E, Uddin M, Ursano RJ, van den Heuvel LL, Van Hooff M, Vermetten E, Vinkers CH, Voisey J, Wang Y, Wang Z, Werge T, Williams MA, Williamson DE, Winternitz S, Wolf C, Wolf EJ, Yehuda R, Young KA, Young RM, Zhao H, Zoellner LA, Haas M, Lasseter H, Provost AC, Salem RM, Sebat J, Shaffer RA, Wu T, Ripke S, Daly MJ, Ressler KJ, Koenen KC, Stein MB, Nievergelt CM. PMID: 34865855; PMCID: PMC8917986.
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15 Fields:
Translation:
Humans
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Chronic presence of blood circulating anti-NMDAR1 autoantibodies impairs cognitive function in mice. PLoS One. 2021; 16(9):e0256972.
Yue W, Caldwell S, Risbrough V, Powell S, Zhou X. PMID: 34473764; PMCID: PMC8412244.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCellsPHPublic Health
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PubMed Mentions:
5
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Examining Individual and Synergistic Contributions of PTSD and Genetics to Blood Pressure: A Trans-Ethnic Meta-Analysis. Front Neurosci. 2021; 15:678503.
Sumner JA, Maihofer AX, Michopoulos V, Rothbaum AO, Almli LM, Andreassen OA, Ashley-Koch AE, Baker DG, Beckham JC, Bradley B, Breen G, Coleman JRI, Dale AM, Dennis MF, Feeny NC, Franz CE, Garrett ME, Gillespie CF, Guffanti G, Hauser MA, Hemmings SMJ, Jovanovic T, Kimbrel NA, Kremen WS, Lawford BR, Logue MW, Lori A, Lyons MJ, Maples-Keller J, Mavissakalian MR, McGlinchey RE, Mehta D, Mellor R, Milberg W, Miller MW, Morris CP, Panizzon MS, Ressler KJ, Risbrough VB, Rothbaum BO, Roy-Byrne P, Seedat S, Smith AK, Stevens JS, van den Heuvel LL, Voisey J, Young RM, Zoellner LA, Nievergelt CM, Wolf EJ. PMID: 34248484; PMCID: PMC8262489.
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PubMed Mentions:
5
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Systematic Review and Methodological Considerations for the Use of Single Prolonged Stress and Fear Extinction Retention in Rodents. Front Behav Neurosci. 2021; 15:652636.
Ferland-Beckham C, Chaby LE, Daskalakis NP, Knox D, Liberzon I, Lim MM, McIntyre C, Perrine SA, Risbrough VB, Sabban EL, Jeromin A, Haas M. PMID: 34054443; PMCID: PMC8162789.
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PubMed Mentions:
13
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Concordant neurophysiological signatures of cognitive control in humans and rats. Neuropsychopharmacology. 2021 06; 46(7):1252-1262.
Robble MA, Schroder HS, Kangas BD, Nickels S, Breiger M, Iturra-Mena AM, Perlo S, Cardenas E, Der-Avakian A, Barnes SA, Leutgeb S, Risbrough VB, Vitaliano G, Bergman J, Carlezon WA, Pizzagalli DA. PMID: 33746206; PMCID: PMC8134486.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Reelin deficiency contributes to long-term behavioral abnormalities induced by chronic adolescent exposure to Δ9-tetrahydrocannabinol in mice. Neuropharmacology. 2021 04 01; 187:108495.
Iemolo A, Montilla-Perez P, Nguyen J, Risbrough VB, Taffe MA, Telese F. PMID: 33582152; PMCID: PMC7989547.
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PubMed Mentions:
5 Fields:
Translation:
Animals
-
The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial. Neuropsychopharmacology. 2021 04; 46(5):1011-1019.
Paulus MP, Stein MB, Simmons AN, Risbrough VB, Halter R, Chaplan SR. PMID: 33335310; PMCID: PMC8105363.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR. Nat Commun. 2020 11 24; 11(1):5965.
Smith AK, Ratanatharathorn A, Maihofer AX, Naviaux RK, Aiello AE, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Boks MP, Bromet E, Dennis M, Galea S, Garrett ME, Geuze E, Guffanti G, Hauser MA, Katrinli S, Kilaru V, Kessler RC, Kimbrel NA, Koenen KC, Kuan PF, Li K, Logue MW, Lori A, Luft BJ, Miller MW, Naviaux JC, Nugent NR, Qin X, Ressler KJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Wang L, Youssef NA, INTRuST Clinical Consortium, VA Mid-Atlantic MIRECC Workgroup, PGC PTSD Epigenetics Workgroup, Uddin M, Nievergelt CM. PMID: 33235198; PMCID: PMC7686485.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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C-Reactive Protein: Marker of risk for post-traumatic stress disorder and its potential for a mechanistic role in trauma response and recovery. Eur J Neurosci. 2022 05; 55(9-10):2297-2310.
Friend SF, Nachnani R, Powell SB, Risbrough VB. PMID: 33131159; PMCID: PMC8087722.
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PubMed Mentions:
18 Translation:
Humans
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Kainate Receptor Auxiliary Subunit NETO2-Related Cued Fear Conditioning Impairments Associate with Defects in Amygdala Development and Excitability. eNeuro. 2020 Jul/Aug; 7(4).
Mennesson M, Orav E, Gigliotta A, Kulesskaya N, Saarnio S, Kirjavainen A, Kesaf S, Winkel F, Llach Pou M, Umemori J, Voikar V, Risbrough V, Partanen J, Castrén E, Lauri SE, Hovatta I. PMID: 32788298; PMCID: PMC7470932.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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DTI-identified microstructural changes in the gray matter of mice overexpressing CRF in the forebrain. Psychiatry Res Neuroimaging. 2020 10 30; 304:111137.
Deslauriers J, Toth M, Scadeng M, McKenna BS, Bussell R, Gresack J, Rissman R, Risbrough VB, Brown GG. PMID: 32731113; PMCID: PMC7508966.
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PubMed Mentions: Fields:
Translation:
HumansAnimals
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Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts. Cell Rep. 2020 06 02; 31(9):107716.
Huckins LM, Chatzinakos C, Breen MS, Hartmann J, Klengel T, da Silva Almeida AC, Dobbyn A, Girdhar K, Hoffman GE, Klengel C, Logue MW, Lori A, Maihofer AX, Morrison FG, Nguyen HT, Park Y, Ruderfer D, Sloofman LG, van Rooij SJH, PTSD Working Group of Psychiatric Genomics Consortium, Baker DG, Chen CY, Cox N, Duncan LE, Geyer MA, Glatt SJ, Im HK, Risbrough VB, Smoller JW, Stein DJ, Yehuda R, Liberzon I, Koenen KC, Jovanovic T, Kellis M, Miller MW, Bacanu SA, Nievergelt CM, Buxbaum JD, Sklar P, Ressler KJ, Stahl EA, Daskalakis NP. PMID: 32492425; PMCID: PMC7359754.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci. Clin Epigenetics. 2020 03 14; 12(1):46.
Logue MW, Miller MW, Wolf EJ, Huber BR, Morrison FG, Zhou Z, Zheng Y, Smith AK, Daskalakis NP, Ratanatharathorn A, Uddin M, Nievergelt CM, Ashley-Koch AE, Baker DG, Beckham JC, Garrett ME, Boks MP, Geuze E, Grant GA, Hauser MA, Kessler RC, Kimbrel NA, Maihofer AX, Marx CE, Qin XJ, Risbrough VB, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Ware EB, Stone A, Schichman SA, McGlinchey RE, Milberg WP, Hayes JP, Verfaellie M, Traumatic Stress Brain Study Group. PMID: 32171335; PMCID: PMC7071645.
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PubMed Mentions:
45 Fields:
Translation:
HumansCells
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Genomic influences on self-reported childhood maltreatment. Transl Psychiatry. 2020 01 27; 10(1):38.
Dalvie S, Maihofer AX, Coleman JRI, Bradley B, Breen G, Brick LA, Chen CY, Choi KW, Duncan LE, Guffanti G, Haas M, Harnal S, Liberzon I, Nugent NR, Provost AC, Ressler KJ, Torres K, Amstadter AB, Bryn Austin S, Baker DG, Bolger EA, Bryant RA, Calabrese JR, Delahanty DL, Farrer LA, Feeny NC, Flory JD, Forbes D, Galea S, Gautam A, Gelernter J, Hammamieh R, Jett M, Junglen AG, Kaufman ML, Kessler RC, Khan A, Kranzler HR, Lebois LAM, Marmar C, Mavissakalian MR, McFarlane A, Donnell MO, Orcutt HK, Pietrzak RH, Risbrough VB, Roberts AL, Rothbaum AO, Roy-Byrne P, Ruggiero K, Seligowski AV, Sheerin CM, Silove D, Smoller JW, Stein MB, Teicher MH, Ursano RJ, Van Hooff M, Winternitz S, Wolff JD, Yehuda R, Zhao H, Zoellner LA, Stein DJ, Koenen KC, Nievergelt CM. PMID: 32066696; PMCID: PMC7026037.
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PubMed Mentions:
27 Fields:
Translation:
Humans
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Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder. Clin Epigenetics. 2020 01 13; 12(1):11.
Snijders C, Maihofer AX, Ratanatharathorn A, Baker DG, Boks MP, Geuze E, Jain S, Kessler RC, Pishva E, Risbrough VB, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, PGC PTSD EWAS Consortium, Smith AK, Uddin M, Rutten BPF, Nievergelt CM. PMID: 31931860; PMCID: PMC6958602.
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PubMed Mentions:
34 Fields:
Translation:
HumansCells
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Angiotensin II Signaling and Fear Extinction: Translational Evidence and Novel Receptor Targets. Biol Psychiatry. 2019 12 15; 86(12):874-876.
Stout DM, Risbrough VB. PMID: 31753101.
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PubMed Mentions:
9 Fields:
Translation:
Cells
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Impact of TBI, PTSD, and Hearing Loss on Tinnitus Progression in a US Marine Cohort. Mil Med. 2019 12 01; 184(11-12):839-846.
Clifford RE, Baker D, Risbrough VB, Huang M, Yurgil KA. PMID: 30793178.
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PubMed Mentions:
13 Fields:
Translation:
Humans
-
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PubMed Mentions:
12 Fields:
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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci. Nat Commun. 2019 10 08; 10(1):4558.
Nievergelt CM, Maihofer AX, Klengel T, Atkinson EG, Chen CY, Choi KW, Coleman JRI, Dalvie S, Duncan LE, Gelernter J, Levey DF, Logue MW, Polimanti R, Provost AC, Ratanatharathorn A, Stein MB, Torres K, Aiello AE, Almli LM, Amstadter AB, Andersen SB, Andreassen OA, Arbisi PA, Ashley-Koch AE, Austin SB, Avdibegovic E, Babic D, Bækvad-Hansen M, Baker DG, Beckham JC, Bierut LJ, Bisson JI, Boks MP, Bolger EA, Børglum AD, Bradley B, Brashear M, Breen G, Bryant RA, Bustamante AC, Bybjerg-Grauholm J, Calabrese JR, Caldas-de-Almeida JM, Dale AM, Daly MJ, Daskalakis NP, Deckert J, Delahanty DL, Dennis MF, Disner SG, Domschke K, Dzubur-Kulenovic A, Erbes CR, Evans A, Farrer LA, Feeny NC, Flory JD, Forbes D, Franz CE, Galea S, Garrett ME, Gelaye B, Geuze E, Gillespie C, Uka AG, Gordon SD, Guffanti G, Hammamieh R, Harnal S, Hauser MA, Heath AC, Hemmings SMJ, Hougaard DM, Jakovljevic M, Jett M, Johnson EO, Jones I, Jovanovic T, Qin XJ, Junglen AG, Karstoft KI, Kaufman ML, Kessler RC, Khan A, Kimbrel NA, King AP, Koen N, Kranzler HR, Kremen WS, Lawford BR, Lebois LAM, Lewis CE, Linnstaedt SD, Lori A, Lugonja B, Luykx JJ, Lyons MJ, Maples-Keller J, Marmar C, Martin AR, Martin NG, Maurer D, Mavissakalian MR, McFarlane A, McGlinchey RE, McLaughlin KA, McLean SA, McLeay S, Mehta D, Milberg WP, Miller MW, Morey RA, Morris CP, Mors O, Mortensen PB, Neale BM, Nelson EC, Nordentoft M, Norman SB, O'Donnell M, Orcutt HK, Panizzon MS, Peters ES, Peterson AL, Peverill M, Pietrzak RH, Polusny MA, Rice JP, Ripke S, Risbrough VB, Roberts AL, Rothbaum AO, Rothbaum BO, Roy-Byrne P, Ruggiero K, Rung A, Rutten BPF, Saccone NL, Sanchez SE, Schijven D, Seedat S, Seligowski AV, Seng JS, Sheerin CM, Silove D, Smith AK, Smoller JW, Sponheim SR, Stein DJ, Stevens JS, Sumner JA, Teicher MH, Thompson WK, Trapido E, Uddin M, Ursano RJ, van den Heuvel LL, Van Hooff M, Vermetten E, Vinkers CH, Voisey J, Wang Y, Wang Z, Werge T, Williams MA, Williamson DE, Winternitz S, Wolf C, Wolf EJ, Wolff JD, Yehuda R, Young RM, Young KA, Zhao H, Zoellner LA, Liberzon I, Ressler KJ, Haas M, Koenen KC. PMID: 31594949; PMCID: PMC6783435.
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PubMed Mentions:
245 Fields:
Translation:
Humans
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Assessing Neuronal and Astrocyte Derived Exosomes From Individuals With Mild Traumatic Brain Injury for Markers of Neurodegeneration and Cytotoxic Activity. Front Neurosci. 2019; 13:1005.
Winston CN, Romero HK, Ellisman M, Nauss S, Julovich DA, Conger T, Hall JR, Campana W, O'Bryant SE, Nievergelt CM, Baker DG, Risbrough VB, Rissman RA. PMID: 31680797; PMCID: PMC6797846.
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PubMed Mentions:
51
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Localization of amyloid beta peptides to locus coeruleus and medial prefrontal cortex in corticotropin releasing factor overexpressing male and female mice. Brain Struct Funct. 2019 Sep; 224(7):2385-2405.
Ross JA, Alexis R, Reyes BAS, Risbrough V, Van Bockstaele EJ. PMID: 31250157; PMCID: PMC7371412.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Common pathways and communication between the brain and heart: connecting post-traumatic stress disorder and heart failure. Stress. 2019 09; 22(5):530-547.
Wilson MA, Liberzon I, Lindsey ML, Lokshina Y, Risbrough VB, Sah R, Wood SK, Williamson JB, Spinale FG. PMID: 31161843; PMCID: PMC6690762.
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PubMed Mentions:
13 Fields:
Translation:
Humans
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Characterizing the neural circuitry associated with configural threat learning. Brain Res. 2019 09 15; 1719:225-234.
Stout DM, Glenn DE, Acheson DT, Simmons AN, Risbrough VB. PMID: 31173725; PMCID: PMC7148156.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Heritable Differences in Catecholamine Signaling Modulate Susceptibility to Trauma and Response to Methylphenidate Treatment: Relevance for PTSD. Front Behav Neurosci. 2019; 13:111.
Deslauriers J, Toth M, Zhou X, Risbrough VB. PMID: 31164811; PMCID: PMC6534065.
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PubMed Mentions:
5
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MEG Working Memory N-Back Task Reveals Functional Deficits in Combat-Related Mild Traumatic Brain Injury. Cereb Cortex. 2019 05 01; 29(5):1953-1968.
Huang MX, Nichols S, Robb-Swan A, Angeles-Quinto A, Harrington DL, Drake A, Huang CW, Song T, Diwakar M, Risbrough VB, Matthews S, Clifford R, Cheng CK, Huang JW, Sinha A, Yurgil KA, Ji Z, Lerman I, Lee RR, Baker DG. PMID: 29668852.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Kainate receptor auxiliary subunit NETO2 is required for normal fear expression and extinction. Neuropsychopharmacology. 2019 10; 44(11):1855-1866.
Mennesson M, Rydgren E, Lipina T, Sokolowska E, Kulesskaya N, Morello F, Ivakine E, Voikar V, Risbrough V, Partanen J, Hovatta I. PMID: 30770891; PMCID: PMC6784901.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Aversive distractors modulate affective working memory in frontoparietal regions. Emotion. 2020 Mar; 20(2):286-295.
Stout DM, Bomyea J, Risbrough VB, Simmons AN. PMID: 30570314.
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PubMed Mentions:
9 Fields:
Translation:
Humans
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Measuring novel antecedents of mental illness: the Questionnaire of Unpredictability in Childhood. Neuropsychopharmacology. 2019 04; 44(5):876-882.
Glynn LM, Stern HS, Howland MA, Risbrough VB, Baker DG, Nievergelt CM, Baram TZ, Davis EP. PMID: 30470840; PMCID: PMC6461958.
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PubMed Mentions:
40 Fields:
Translation:
Humans
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Heart rate variability and emotion regulation among individuals with obesity and loss of control eating. Physiol Behav. 2019 02 01; 199:73-78.
Godfrey KM, Juarascio A, Manasse S, Minassian A, Risbrough V, Afari N. PMID: 30414883; PMCID: PMC6492031.
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PubMed Mentions:
11 Fields:
Translation:
Humans
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View in:
PubMed Mentions:
11
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REM sleep and safety signal learning in posttraumatic stress disorder: A preliminary study in military veterans. Neurobiol Stress. 2018 Nov; 9:22-28.
Straus LD, Norman SB, Risbrough VB, Acheson DT, Drummond SPA. PMID: 30116769; PMCID: PMC6084022.
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PubMed Mentions:
17
-
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
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The Relationship Between Chronic Pain and Neurocognitive Function: A Systematic Review. Clin J Pain. 2018 03; 34(3):262-275.
Higgins DM, Martin AM, Baker DG, Vasterling JJ, Risbrough V. PMID: 28719507; PMCID: PMC5771985.
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PubMed Mentions:
38 Fields:
Translation:
Humans
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A signal detection-item response theory model for evaluating neuropsychological measures. J Clin Exp Neuropsychol. 2018 10; 40(8):745-760.
Thomas ML, Brown GG, Gur RC, Moore TM, Patt VM, Risbrough VB, Baker DG. PMID: 29402152; PMCID: PMC6050112.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Individual variation in working memory is associated with fear extinction performance. Behav Res Ther. 2018 03; 102:52-59.
Stout DM, Acheson DT, Moore TM, Gur RC, Baker DG, Geyer MA, Risbrough VB, MRS Team. PMID: 29331727; PMCID: PMC6182776.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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The Future of Contextual Fear Learning for PTSD Research: A Methodological Review of Neuroimaging Studies. Curr Top Behav Neurosci. 2018; 38:207-228.
Glenn DE, Risbrough VB, Simmons AN, Acheson DT, Stout DM. PMID: 29063483.
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PubMed Mentions:
6 Fields:
Translation:
Humans
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Does Anhedonia Presage Increased Risk of Posttraumatic Stress Disorder? : Adolescent Anhedonia and Posttraumatic Disorders. Curr Top Behav Neurosci. 2018; 38:249-265.
Risbrough VB, Glynn LM, Davis EP, Sandman CA, Obenaus A, Stern HS, Keator DB, Yassa MA, Baram TZ, Baker DG. PMID: 29796839; PMCID: PMC9167566.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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Sleep Disruption, Safety Learning, and Fear Extinction in Humans: Implications for Posttraumatic Stress Disorder. Curr Top Behav Neurosci. 2018; 38:193-205.
Straus LD, Drummond SPA, Risbrough VB, Norman SB. PMID: 28942597.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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Traumatic stress and accelerated DNA methylation age: A meta-analysis. Psychoneuroendocrinology. 2018 06; 92:123-134.
Wolf EJ, Maniates H, Nugent N, Maihofer AX, Armstrong D, Ratanatharathorn A, Ashley-Koch AE, Garrett M, Kimbrel NA, Lori A, Aiello AE, Baker DG, Beckham JC, Boks MP, Galea S, Geuze E, Hauser MA, Kessler RC, Koenen KC, Miller MW, Ressler KJ, Risbrough V, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Uddin M, Smith AK, Nievergelt CM, Logue MW. PMID: 29452766; PMCID: PMC5924645.
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PubMed Mentions:
115 Fields:
Translation:
HumansCells
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Current Status of Animal Models of Posttraumatic Stress Disorder: Behavioral and Biological Phenotypes, and Future Challenges in Improving Translation. Biol Psychiatry. 2018 05 15; 83(10):895-907.
Deslauriers J, Toth M, Der-Avakian A, Risbrough VB. PMID: 29338843; PMCID: PMC6085893.
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PubMed Mentions:
102 Fields:
Translation:
HumansAnimals
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PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma. Neuropsychopharmacology. 2018 02; 43(3):469-481.
Breen MS, Tylee DS, Maihofer AX, Neylan TC, Mehta D, Binder EB, Chandler SD, Hess JL, Kremen WS, Risbrough VB, Woelk CH, Baker DG, Nievergelt CM, Tsuang MT, Buxbaum JD, Glatt SJ. PMID: 28925389; PMCID: PMC5770765.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Inhibition of p75 neurotrophin receptor does not rescue cognitive impairment in adulthood after isoflurane exposure in neonatal mice. Br J Anaesth. 2017 Sep 01; 119(3):465-471.
Schilling JM, Kassan A, Mandyam C, Pearn ML, Voong A, Grogman GG, Risbrough VB, Niesman IR, Patel HH, Patel PM, Head BP. PMID: 28969308; PMCID: PMC6172965.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Effects of military service and deployment on clinical symptomatology: The role of trauma exposure and social support. J Psychiatr Res. 2017 12; 95:121-128.
Moore TM, Risbrough VB, Baker DG, Larson GE, Glenn DE, Nievergelt CM, Maihofer A, Port AM, Jackson CT, Ruparel K, Gur RC. PMID: 28843074; PMCID: PMC5653464.
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PubMed Mentions:
15 Fields:
Translation:
Humans
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COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma. Depress Anxiety. 2018 01; 35(1):32-42.
Deslauriers J, Acheson DT, Maihofer AX, Nievergelt CM, Baker DG, Geyer MA, Risbrough VB, Marine Resiliency Study Team. PMID: 28833952; PMCID: PMC5760328.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 08 02; 8:16140.
Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. PMID: 28767105; PMCID: PMC5543301.
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PubMed Mentions:
4 Fields:
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Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 06 14; 8:15805.
Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. PMID: 28613276; PMCID: PMC5474732.
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PubMed Mentions:
58 Fields:
Translation:
Humans
-
Fear learning alterations after traumatic brain injury and their role in development of posttraumatic stress symptoms. Depress Anxiety. 2017 08; 34(8):723-733.
Glenn DE, Acheson DT, Geyer MA, Nievergelt CM, Baker DG, Risbrough VB, MRS-II Team. PMID: 28489272.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Immune signaling mechanisms of PTSD risk and symptom development: insights from animal models. Curr Opin Behav Sci. 2017 Apr; 14:123-132.
Deslauriers J, Powell S, Risbrough VB. PMID: 28758144; PMCID: PMC5525319.
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PubMed Mentions:
27
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Sleep Deprivation Disrupts Recall of Conditioned Fear Extinction. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar; 2(2):123-129.
Straus LD, Acheson DT, Risbrough VB, Drummond SPA. PMID: 28758152; PMCID: PMC5526630.
View in:
PubMed Mentions:
33 Fields:
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Effects of LPS-induced immune activation prior to trauma exposure on PTSD-like symptoms in mice. Behav Brain Res. 2017 04 14; 323:117-123.
Deslauriers J, van Wijngaarde M, Geyer MA, Powell S, Risbrough VB. PMID: 28159589.
View in:
PubMed Mentions:
13 Fields:
Translation:
Animals
-
Resting-State Magnetoencephalography Reveals Different Patterns of Aberrant Functional Connectivity in Combat-Related Mild Traumatic Brain Injury. J Neurotrauma. 2017 04 01; 34(7):1412-1426.
Huang MX, Harrington DL, Robb Swan A, Angeles Quinto A, Nichols S, Drake A, Song T, Diwakar M, Huang CW, Risbrough VB, Dale A, Bartsch H, Matthews S, Huang JW, Lee RR, Baker DG. PMID: 27762653.
View in:
PubMed Mentions:
19 Fields:
Translation:
Humans
-
Prepulse Inhibition Deficits in Obsessive-Compulsive Disorder are More Pronounced in Females. Neuropsychopharmacology. 2016 12; 41(13):2963-2964.
Ahmari SE, Risbrough VB, Geyer MA, Simpson HB. PMID: 27818517; PMCID: PMC5101545.
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PubMed Mentions:
11 Fields:
Translation:
Humans
-
HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES. Depress Anxiety. 2016 Mar; 33(3):192-202.
Glenn DE, Acheson DT, Geyer MA, Nievergelt CM, Baker DG, Risbrough VB, MRS Team. PMID: 26878585.
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PubMed Mentions:
10 Fields:
Translation:
Humans
-
PREPULSE INHIBITION DEFICITS ONLY IN FEMALES WITH OBSESSIVE-COMPULSIVE DISORDER. Depress Anxiety. 2016 Mar; 33(3):238-46.
Steinman SA, Ahmari SE, Choo T, Kimeldorf MB, Feit R, Loh S, Risbrough V, Geyer MA, Steinglass JE, Wall M, Schneier FR, Fyer AJ, Simpson HB. PMID: 26878422; PMCID: PMC4806386.
View in:
PubMed Mentions:
12 Fields:
Translation:
Humans
-
Heart Rate Variability and Posttraumatic Stress Disorder. JAMA Psychiatry. 2016 Feb; 73(2):178-9.
Minassian A, Baker DG, Risbrough VB. PMID: 26720754.
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PubMed Mentions: Fields:
Translation:
Humans
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On the Road to Translation for PTSD Treatment: Theoretical and Practical Considerations of the Use of Human Models of Conditioned Fear for Drug Development. Curr Top Behav Neurosci. 2016; 28:173-96.
Risbrough VB, Glenn DE, Baker DG. PMID: 27311760.
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PubMed Mentions:
8 Fields:
Translation:
Humans
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Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines. J Head Trauma Rehabil. 2016 Jan-Feb; 31(1):30-9.
Yurgil KA, Clifford RE, Risbrough VB, Geyer MA, Huang M, Barkauskas DA, Vasterling JJ, MRS Team, Baker DG. PMID: 25699623.
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PubMed Mentions:
5 Fields:
Translation:
Humans
-
Overexpression of Forebrain CRH During Early Life Increases Trauma Susceptibility in Adulthood. Neuropsychopharmacology. 2016 May; 41(6):1681-90.
Toth M, Flandreau EI, Deslauriers J, Geyer MA, Mansuy IM, Merlo Pich E, Risbrough VB. PMID: 26538448; PMCID: PMC4832031.
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PubMed Mentions:
21 Fields:
Translation:
Animals
-
Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice. Biol Psychiatry. 2017 01 15; 81(2):101-110.
Mandyam CD, Schilling JM, Cui W, Egawa J, Niesman IR, Kellerhals SE, Staples MC, Busija AR, Risbrough VB, Posadas E, Grogman GC, Chang JW, Roth DM, Patel PM, Patel HH, Head BP. PMID: 26592463; PMCID: PMC4826329.
View in:
PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 2015 Oct; 72(10):979-86.
Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer MA, Risbrough VB, Marine Resiliency Study Team. PMID: 26353072.
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PubMed Mentions:
65 Fields:
Translation:
Humans
-
Oxytocin enhancement of fear extinction: a new target for facilitating exposure-based treatments? Biol Psychiatry. 2015 Aug 01; 78(3):154-5.
Acheson DT, Risbrough VB. PMID: 26143973.
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PubMed Mentions:
3 Fields:
Translation:
Humans
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Fear extinction memory performance in a sample of stable, euthymic patients with bipolar disorder. J Affect Disord. 2015 Oct 01; 185:230-8.
Acheson DT, Eyler LT, Resovsky J, Tsan E, Risbrough VB. PMID: 26247493.
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PubMed Mentions:
7 Fields:
Translation:
Humans
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Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol. 2015 Jun 02; 18(11):pyv063.
Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer MA, Zhou X. PMID: 26037489; PMCID: PMC4756721.
View in:
PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats. Neuropharmacology. 2015 Oct; 97:357-64.
Li X, Kaczanowska K, Finn MG, Markou A, Risbrough VB. PMID: 26002628; PMCID: PMC4537349.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
Maximizing the utility of a single site randomized controlled psychotherapy trial. Contemp Clin Trials. 2015 May; 42:244-51.
Norman SB, Haller M, Spadoni AD, Drummond SP, Risbrough V, Hamblen JL, Trim RS, Blanes EX. PMID: 25933919; PMCID: PMC8876249.
View in:
PubMed Mentions:
7 Fields:
Translation:
Humans
-
Intranasal oxytocin administration prior to exposure therapy for arachnophobia impedes treatment response. Depress Anxiety. 2015 Jun; 32(6):400-7.
Acheson DT, Feifel D, Kamenski M, Mckinney R, Risbrough VB. PMID: 25826649.
View in:
PubMed Mentions:
20 Fields:
Translation:
HumansAnimals
-
Gene networks specific for innate immunity define post-traumatic stress disorder. Mol Psychiatry. 2015 Dec; 20(12):1538-45.
Breen MS, Maihofer AX, Glatt SJ, Tylee DS, Chandler SD, Tsuang MT, Risbrough VB, Baker DG, O'Connor DT, Nievergelt CM, Woelk CH. PMID: 25754082; PMCID: PMC4565790.
View in:
PubMed Mentions:
92 Fields:
Translation:
Humans
-
Pavlovian conditioning to hedonic food cues in overweight and lean individuals. Appetite. 2015 Apr; 87:56-61.
Meyer MD, Risbrough VB, Liang J, Boutelle KN. PMID: 25526826.
View in:
PubMed Mentions:
18 Fields:
Translation:
HumansAnimalsCTClinical Trials
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Cell type-specific modifications of corticotropin-releasing factor (CRF) and its type 1 receptor (CRF1) on startle behavior and sensorimotor gating. Psychoneuroendocrinology. 2015 Mar; 53:16-28.
Flandreau E, Risbrough V, Lu A, Ableitner M, Geyer MA, Holsboer F, Deussing JM. PMID: 25575243; PMCID: PMC4364548.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Design and implementation of a study evaluating extinction processes to food cues in obese children: the Intervention for Regulations of Cues Trial (iROC). Contemp Clin Trials. 2015 Jan; 40:95-104.
Boutelle KN, Liang J, Knatz S, Matheson B, Risbrough V, Strong D, Rhee KE, Craske MG, Zucker N, Bouton ME. PMID: 25461494; PMCID: PMC4314468.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansCTClinical Trials
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Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. Psychoneuroendocrinology. 2015 Jan; 51:459-71.
Nievergelt CM, Maihofer AX, Mustapic M, Yurgil KA, Schork NJ, Miller MW, Logue MW, Geyer MA, Risbrough VB, O'Connor DT, Baker DG. PMID: 25456346.
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PubMed Mentions:
73 Fields:
Translation:
Humans
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Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines. Psychoneuroendocrinology. 2015 Jan; 51:495-505.
Acheson DT, Geyer MA, Baker DG, Nievergelt CM, Yurgil K, Risbrough VB, MRS-II Team. PMID: 25444643; PMCID: PMC4345165.
View in:
PubMed Mentions:
26 Fields:
Translation:
Humans
-
Fear conditioning, safety learning, and sleep in humans. J Neurosci. 2014 Aug 27; 34(35):11754-60.
Marshall AJ, Acheson DT, Risbrough VB, Straus LD, Drummond SP. PMID: 25164670; PMCID: PMC6608408.
View in:
PubMed Mentions:
39 Fields:
Translation:
Humans
-
Voxel-wise resting-state MEG source magnitude imaging study reveals neurocircuitry abnormality in active-duty service members and veterans with PTSD. Neuroimage Clin. 2014; 5:408-19.
Huang MX, Yurgil KA, Robb A, Angeles A, Diwakar M, Risbrough VB, Nichols SL, McLay R, Theilmann RJ, Song T, Huang CW, Lee RR, Baker DG. PMID: 25180160; PMCID: PMC4145534.
View in:
PubMed Mentions:
34 Fields:
Translation:
Humans
-
Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy. Transl Psychiatry. 2014 Jun 17; 4:e400.
Naviaux JC, Schuchbauer MA, Li K, Wang L, Risbrough VB, Powell SB, Naviaux RK. PMID: 24937094; PMCID: PMC4080315.
View in:
PubMed Mentions:
64 Fields:
Translation:
Animals
-
Single-subject-based whole-brain MEG slow-wave imaging approach for detecting abnormality in patients with mild traumatic brain injury. Neuroimage Clin. 2014; 5:109-19.
Huang MX, Nichols S, Baker DG, Robb A, Angeles A, Yurgil KA, Drake A, Levy M, Song T, McLay R, Theilmann RJ, Diwakar M, Risbrough VB, Ji Z, Huang CW, Chang DG, Harrington DL, Muzzatti L, Canive JM, Christopher Edgar J, Chen YH, Lee RR. PMID: 25009772; PMCID: PMC4087185.
View in:
PubMed Mentions:
35 Fields:
Translation:
Humans
-
Heart rate variability characteristics in a large group of active-duty marines and relationship to posttraumatic stress. Psychosom Med. 2014 May; 76(4):292-301.
Minassian A, Geyer MA, Baker DG, Nievergelt CM, O'Connor DT, Risbrough VB, Marine Resiliency Study Team. PMID: 24804881; PMCID: PMC4062545.
View in:
PubMed Mentions:
43 Fields:
Translation:
Humans
-
Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry. Behav Brain Res. 2014 Jul 01; 267:6-11.
Schilling JM, Cui W, Godoy JC, Risbrough VB, Niesman IR, Roth DM, Patel PM, Drummond JC, Patel HH, Zemljic-Harpf AE, Head BP. PMID: 24657594; PMCID: PMC4059187.
View in:
PubMed Mentions:
10 Fields:
Translation:
Animals
-
Generation and characterization of humanized mice carrying COMT158 Met/Val alleles. Neuropsychopharmacology. 2014 Jul; 39(8):1823-32.
Risbrough V, Ji B, Hauger R, Zhou X. PMID: 24509724; PMCID: PMC4059890.
View in:
PubMed Mentions:
22 Fields:
Translation:
HumansAnimals
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Psychophysiology in the study of psychological trauma: where are we now and where do we need to be? Curr Top Behav Neurosci. 2014; 21:157-83.
Acheson DT, Geyer MA, Risbrough VB. PMID: 25158622.
View in:
PubMed Mentions:
7 Fields:
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Inhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating. Psychopharmacology (Berl). 2014 May; 231(10):2189-97.
Gresack JE, Seymour PA, Schmidt CJ, Risbrough VB. PMID: 24363077; PMCID: PMC4017785.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Sleep deprivation impairs performance in the 5-choice continuous performance test: similarities between humans and mice. Behav Brain Res. 2014 Mar 15; 261:40-8.
van Enkhuizen J, Acheson D, Risbrough V, Drummond S, Geyer MA, Young JW. PMID: 24333377; PMCID: PMC3937379.
View in:
PubMed Mentions:
34 Fields:
Translation:
HumansAnimals
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Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice. Neuropsychopharmacology. 2014 May; 39(6):1409-19.
Toth M, Gresack JE, Bangasser DA, Plona Z, Valentino RJ, Flandreau EI, Mansuy IM, Merlo-Pich E, Geyer MA, Risbrough VB. PMID: 24326400; PMCID: PMC3988544.
View in:
PubMed Mentions:
20 Fields:
Translation:
Animals
-
The role of PKC signaling in CRF-induced modulation of startle. Psychopharmacology (Berl). 2013 Oct; 229(4):579-89.
Toth M, Gresack JE, Hauger RL, Halberstadt AL, Risbrough VB. PMID: 23722830; PMCID: PMC3784645.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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The effect of intranasal oxytocin treatment on conditioned fear extinction and recall in a healthy human sample. Psychopharmacology (Berl). 2013 Sep; 229(1):199-208.
Acheson D, Feifel D, de Wilde S, McKinney R, Lohr J, Risbrough V. PMID: 23644911; PMCID: PMC5458114.
View in:
PubMed Mentions:
59 Fields:
Translation:
Humans
-
The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice. Arch Pharm Res. 2013 Jul; 36(7):854-63.
Liu X, Hong SI, Park SJ, Dela Peña JB, Che H, Yoon SY, Kim DH, Kim JM, Cai M, Risbrough V, Geyer MA, Shin CY, Cheong JH, Park H, Lew JH, Ryu JH. PMID: 23543630.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
-
Short-term recognition memory correlates with regional CNS expression of microRNA-138 in mice. Am J Geriatr Psychiatry. 2013 May; 21(5):461-73.
Tatro ET, Risbrough V, Soontornniyomkij B, Young J, Shumaker-Armstrong S, Jeste DV, Achim CL. PMID: 23570889; PMCID: PMC3660985.
View in:
PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Impaired conditioned fear response and startle reactivity in epinephrine-deficient mice. Behav Pharmacol. 2013 Feb; 24(1):1-9.
Toth M, Ziegler M, Sun P, Gresack J, Risbrough V. PMID: 23268986; PMCID: PMC3558035.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
-
Comparison of the effects of the GABAB receptor positive modulator BHF177 and the GABAB receptor agonist baclofen on anxiety-like behavior, learning, and memory in mice. Neuropharmacology. 2013 Jul; 70:156-67.
Li X, Risbrough VB, Cates-Gatto C, Kaczanowska K, Finn MG, Roberts AJ, Markou A. PMID: 23376712; PMCID: PMC3644349.
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PubMed Mentions:
19 Fields:
Translation:
Animals
-
A consideration of select pre-trauma factors as key vulnerabilities in PTSD. Clin Psychol Rev. 2012 Nov; 32(7):630-41.
Bomyea J, Risbrough V, Lang AJ. PMID: 22917742; PMCID: PMC3444146.
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PubMed Mentions:
49 Fields:
Translation:
Humans
-
Effects of anxiolytic treatment on potentiated startle during aversive image anticipation. Hum Psychopharmacol. 2012 Jul; 27(4):419-27.
Acheson DT, Stein MB, Paulus MP, Ravindran L, Simmons AN, Lohr JB, Risbrough VB. PMID: 22782542.
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PubMed Mentions:
8 Fields:
Translation:
Humans
-
Predictors of risk and resilience for posttraumatic stress disorder among ground combat Marines: methods of the Marine Resiliency Study. Prev Chronic Dis. 2012; 9:E97.
Baker DG, Nash WP, Litz BT, Geyer MA, Risbrough VB, Nievergelt CM, O'Connor DT, Larson GE, Schork NJ, Vasterling JJ, Hammer PS, Webb-Murphy JA, MRS Team. PMID: 22575082; PMCID: PMC3431952.
View in:
PubMed Mentions:
40 Fields:
Translation:
Humans
-
View in:
PubMed Mentions:
6 Fields:
Translation:
HumansAnimals
-
Hippocampal calbindin-1 immunoreactivity correlate of recognition memory performance in aged mice. Neurosci Lett. 2012 May 10; 516(1):161-5.
Soontornniyomkij V, Risbrough VB, Young JW, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 22503902; PMCID: PMC3338865.
View in:
PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Decreased startle modulation during anticipation in the postpartum period in comparison to late pregnancy. Arch Womens Ment Health. 2012 Apr; 15(2):87-94.
Hellgren C, Bannbers E, Åkerud H, Risbrough V, Poromaa IS. PMID: 22315106; PMCID: PMC3305879.
View in:
PubMed Mentions:
8 Fields:
Translation:
Humans
-
Impaired sensorimotor gating in unmedicated adults with obsessive-compulsive disorder. Neuropsychopharmacology. 2012 Apr; 37(5):1216-23.
Ahmari SE, Risbrough VB, Geyer MA, Simpson HB. PMID: 22218093; PMCID: PMC3306882.
View in:
PubMed Mentions:
86 Fields:
Translation:
Humans
-
Neuropharmacology special issue on posttraumatic stress disorder (PTSD): current state of the art in clinical and preclinical PTSD research. Neuropharmacology. 2012 Feb; 62(2):539-41.
Risbrough VB, Stein MB. PMID: 21875608.
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PubMed Mentions: Fields:
Translation:
Humans
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Factor analysis of attentional set-shifting performance in young and aged mice. Behav Brain Funct. 2011 Aug 12; 7:33.
Tanaka S, Young JW, Gresack JE, Geyer MA, Risbrough VB. PMID: 21838910; PMCID: PMC3174878.
View in:
PubMed Mentions:
5 Fields:
Translation:
Animals
-
Pharmacological treatment of PTSD - established and new approaches. Neuropharmacology. 2012 Feb; 62(2):617-27.
Steckler T, Risbrough V. PMID: 21736888; PMCID: PMC3204327.
View in:
PubMed Mentions:
72 Fields:
Translation:
Humans
-
Hippocampal dysfunction effects on context memory: possible etiology for posttraumatic stress disorder. Neuropharmacology. 2012 Feb; 62(2):674-85.
Acheson DT, Gresack JE, Risbrough VB. PMID: 21596050; PMCID: PMC3175276.
View in:
PubMed Mentions:
85 Fields:
Translation:
Humans
-
Enhanced effects of amphetamine but reduced effects of the hallucinogen, 5-MeO-DMT, on locomotor activity in 5-HT(1A) receptor knockout mice: implications for schizophrenia. Neuropharmacology. 2011 Jul-Aug; 61(1-2):209-16.
van den Buuse M, Ruimschotel E, Martin S, Risbrough VB, Halberstadt AL. PMID: 21501627; PMCID: PMC3866100.
View in:
PubMed Mentions:
19 Fields:
Translation:
Animals
-
Patients with premenstrual dysphoric disorder have increased startle modulation during anticipation in the late luteal phase period in comparison to control subjects. Psychoneuroendocrinology. 2011 Sep; 36(8):1184-92.
Bannbers E, Kask K, Wikström J, Risbrough V, Poromaa IS. PMID: 21435793.
View in:
PubMed Mentions:
7 Fields:
Translation:
HumansCells
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Increased hippocampal accumulation of autophagosomes predicts short-term recognition memory impairment in aged mice. Age (Dordr). 2012 Apr; 34(2):305-16.
Soontornniyomkij V, Risbrough VB, Young JW, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 21431350; PMCID: PMC3312638.
View in:
PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
-
Disruption of prepulse inhibition by 3,4-methylenedioxymethamphetamine (MDMA): comparison between male and female wild-type and 5-HT(1A) receptor knockout mice. Int J Neuropsychopharmacol. 2011 Jul; 14(6):856-61.
van den Buuse M, Becker T, Kwek P, Martin S, Ruimschotel E, Risbrough V. PMID: 21329554.
View in:
PubMed Mentions:
8 Fields:
Translation:
Animals
-
Corticotropin-releasing factor and noradrenergic signalling exert reciprocal control over startle reactivity. Int J Neuropsychopharmacol. 2011 Oct; 14(9):1179-94.
Gresack JE, Risbrough VB. PMID: 21205416; PMCID: PMC3601827.
View in:
PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Initial evidence linking synaptic superoxide production with poor short-term memory in aged mice. Brain Res. 2011 Jan 12; 1368:65-70.
Ali SS, Young JW, Wallace CK, Gresack J, Jeste DV, Geyer MA, Dugan LL, Risbrough VB. PMID: 21075081; PMCID: PMC3018762.
View in:
PubMed Mentions:
19 Fields:
Translation:
AnimalsCells
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The effects of globin on microarray-based gene expression analysis of mouse blood. Mamm Genome. 2010 Jun; 21(5-6):268-75.
Winn ME, Zapala MA, Hovatta I, Risbrough VB, Lillie E, Schork NJ. PMID: 20473674; PMCID: PMC2890980.
View in:
PubMed Mentions:
7 Fields:
Translation:
Animals
-
CRF2 null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice. Neuropeptides. 2010 Aug; 44(4):349-53.
Gresack J, Powell S, Geyer M, Poore MS, Coste S, Risbrough V. PMID: 20466421; PMCID: PMC2888500.
View in:
PubMed Mentions:
3 Fields:
Translation:
Animals
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The mouse attentional-set-shifting task: a method for assaying successful cognitive aging? Cogn Affect Behav Neurosci. 2010 May; 10(2):243-51.
Young JW, Powell SB, Geyer MA, Jeste DV, Risbrough VB. PMID: 20498348; PMCID: PMC2877277.
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PubMed Mentions:
42 Fields:
Translation:
Animals
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Short-term recognition memory impairment is associated with decreased expression of FK506 binding protein 51 in the aged mouse brain. Age (Dordr). 2010 Sep; 32(3):309-22.
Soontornniyomkij V, Risbrough VB, Young JW, Wallace CK, Soontornniyomkij B, Jeste DV, Achim CL. PMID: 20422297; PMCID: PMC2926850.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Age-associated improvements in cross-modal prepulse inhibition in mice. Behav Neurosci. 2010 Feb; 124(1):133-140.
Young JW, Wallace CK, Geyer MA, Risbrough VB. PMID: 20141288; PMCID: PMC3088993.
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PubMed Mentions:
15 Fields:
Translation:
Animals
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Isolation rearing-induced deficits in contextual fear learning do not require CRF(2) receptors. Behav Brain Res. 2010 May 01; 209(1):80-4.
Gresack JE, Risbrough VB, Scott CN, Coste S, Stenzel-Poore M, Geyer MA, Powell SB. PMID: 20097235; PMCID: PMC2832092.
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PubMed Mentions:
21 Fields:
Translation:
Animals
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Behavioral correlates of anxiety. Curr Top Behav Neurosci. 2010; 2:205-28.
Risbrough V. PMID: 21309111.
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PubMed Mentions:
12 Fields:
Translation:
Humans
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Role of CRF receptor signaling in stress vulnerability, anxiety, and depression. Ann N Y Acad Sci. 2009 Oct; 1179:120-43.
Hauger RL, Risbrough V, Oakley RH, Olivares-Reyes JA, Dautzenberg FM. PMID: 19906236; PMCID: PMC3115623.
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PubMed Mentions:
106 Fields:
Translation:
HumansCells
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CRF receptor blockade prevents initiation and consolidation of stress effects on affect in the predator stress model of PTSD. Int J Neuropsychopharmacol. 2010 Jul; 13(6):747-57.
Adamec R, Fougere D, Risbrough V. PMID: 19751543; PMCID: PMC3092595.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Post-traumatic stress disorder: emerging concepts of pharmacotherapy. Expert Opin Emerg Drugs. 2009 Jun; 14(2):251-72.
Baker DG, Nievergelt CM, Risbrough VB. PMID: 19453285; PMCID: PMC2791537.
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PubMed Mentions:
8 Fields:
Translation:
HumansAnimals
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5-HT1A receptor activation is necessary for 5-MeODMT-dependent potentiation of feeding inhibition. Pharmacol Biochem Behav. 2009 Sep; 93(3):349-53.
Duvvuri V, Risbrough VB, Kaye WH, Geyer MA. PMID: 19490926; PMCID: PMC2724836.
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PubMed Mentions:
4 Fields:
Translation:
Animals
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5-HT(2A) and 5-HT(2C) receptors exert opposing effects on locomotor activity in mice. Neuropsychopharmacology. 2009 Jul; 34(8):1958-67.
Halberstadt AL, van der Heijden I, Ruderman MA, Risbrough VB, Gingrich JA, Geyer MA, Powell SB. PMID: 19322172; PMCID: PMC2697271.
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PubMed Mentions:
78 Fields:
Translation:
AnimalsCells
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Using the MATRICS to guide development of a preclinical cognitive test battery for research in schizophrenia. Pharmacol Ther. 2009 May; 122(2):150-202.
Young JW, Powell SB, Risbrough V, Marston HM, Geyer MA. PMID: 19269307; PMCID: PMC2688712.
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PubMed Mentions:
142 Fields:
Translation:
HumansAnimals
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CRF1 and CRF2 receptors are required for potentiated startle to contextual but not discrete cues. Neuropsychopharmacology. 2009 May; 34(6):1494-503.
Risbrough VB, Geyer MA, Hauger RL, Coste S, Stenzel-Poore M, Wurst W, Holsboer F. PMID: 19020499; PMCID: PMC2900918.
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PubMed Mentions:
29 Fields:
Translation:
Animals
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Modification of the effects of 5-methoxy-N,N-dimethyltryptamine on exploratory behavior in rats by monoamine oxidase inhibitors. Psychopharmacology (Berl). 2008 Nov; 201(1):55-66.
Halberstadt AL, Buell MR, Masten VL, Risbrough VB, Geyer MA. PMID: 18604652; PMCID: PMC2929165.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Spontaneous nicotine withdrawal potentiates the effects of stress in rats. Neuropsychopharmacology. 2008 Aug; 33(9):2131-8.
Jonkman S, Risbrough VB, Geyer MA, Markou A. PMID: 18033237; PMCID: PMC2648847.
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PubMed Mentions:
28 Fields:
Translation:
Animals
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Selection for contextual fear conditioning affects anxiety-like behaviors and gene expression. Genes Brain Behav. 2007 Nov; 6(8):736-49.
Ponder CA, Kliethermes CL, Drew MR, Muller J, Das K, Risbrough VB, Crabbe JC, Gilliam TC, Palmer AA. PMID: 17309658.
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PubMed Mentions:
49 Fields:
Translation:
Animals
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Role of dopamine D1 and D2 receptors in CRF-induced disruption of sensorimotor gating. Pharmacol Biochem Behav. 2007 Mar; 86(3):550-8.
Vinkers CH, Risbrough VB, Geyer MA, Caldwell S, Low MJ, Hauger RL. PMID: 17324452; PMCID: PMC1892615.
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PubMed Mentions:
10 Fields:
Translation:
Animals
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Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets. CNS Neurol Disord Drug Targets. 2006 Aug; 5(4):453-79.
Hauger RL, Risbrough V, Brauns O, Dautzenberg FM. PMID: 16918397; PMCID: PMC1925123.
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PubMed Mentions:
142 Fields:
Translation:
HumansAnimalsCells
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Role of corticotropin releasing factor in anxiety disorders: a translational research perspective. Horm Behav. 2006 Nov; 50(4):550-61.
Risbrough VB, Stein MB. PMID: 16870185; PMCID: PMC1884405.
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PubMed Mentions:
83 Fields:
Translation:
HumansAnimalsCells
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Differential contributions of dopamine D1, D2, and D3 receptors to MDMA-induced effects on locomotor behavior patterns in mice. Neuropsychopharmacology. 2006 Nov; 31(11):2349-58.
Risbrough VB, Masten VL, Caldwell S, Paulus MP, Low MJ, Geyer MA. PMID: 16855533.
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PubMed Mentions:
67 Fields:
Translation:
Animals
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Anxiogenic treatments do not increase fear-potentiated startle in mice. Biol Psychiatry. 2005 Jan 01; 57(1):33-43.
Risbrough VB, Geyer MA. PMID: 15607298.
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PubMed Mentions:
17 Fields:
Translation:
Animals
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Corticotropin-releasing factor receptors CRF1 and CRF2 exert both additive and opposing influences on defensive startle behavior. J Neurosci. 2004 Jul 21; 24(29):6545-52.
Risbrough VB, Hauger RL, Roberts AL, Vale WW, Geyer MA. PMID: 15269266; PMCID: PMC6729883.
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PubMed Mentions:
60 Fields:
Translation:
Animals
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Role of corticotropin releasing factor (CRF) receptors 1 and 2 in CRF-potentiated acoustic startle in mice. Psychopharmacology (Berl). 2003 Nov; 170(2):178-87.
Risbrough VB, Hauger RL, Pelleymounter MA, Geyer MA. PMID: 12845406.
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PubMed Mentions:
39 Fields:
Translation:
Animals
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Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors. Neuropsychopharmacology. 2003 Jul; 28(7):1235-46.
Bontempi B, Whelan KT, Risbrough VB, Lloyd GK, Menzaghi F. PMID: 12700710.
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PubMed Mentions:
30 Fields:
Translation:
Animals
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GABA-A and 5-HT1A receptor agonists block expression of fear-potentiated startle in mice. Neuropsychopharmacology. 2003 Apr; 28(4):654-63.
Risbrough VB, Brodkin JD, Geyer MA. PMID: 12655310.
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PubMed Mentions:
30 Fields:
Translation:
Animals
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Selective immunolesioning of the basal forebrain cholinergic neurons in rats: effect on attention using the 5-choice serial reaction time task. Psychopharmacology (Berl). 2002 Oct; 164(1):71-81.
Risbrough V, Bontempi B, Menzaghi F. PMID: 12373421.
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PubMed Mentions:
22 Fields:
Translation:
AnimalsCells
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Effects of (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a selective ligand for nicotinic acetylcholine receptors, in tests of visual attention and distractibility in rats and monkeys. J Pharmacol Exp Ther. 2002 Apr; 301(1):284-92.
Terry AV, Risbrough VB, Buccafusco JJ, Menzaghi F. PMID: 11907185.
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PubMed Mentions:
22 Fields:
Translation:
Animals
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SIB-1553A, (+/-)-4-[[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride, a subtype-selective ligand for nicotinic acetylcholine receptors with putative cognitive-enhancing properties: effects on working and reference memory performances in aged rodents and nonhuman primates. J Pharmacol Exp Ther. 2001 Oct; 299(1):297-306.
Bontempi B, Whelan KT, Risbrough VB, Rao TS, Buccafusco JJ, Lloyd GK, Menzaghi F. PMID: 11561092.
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PubMed Mentions:
13 Fields:
Translation:
Animals
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Clonidine blocks acquisition but not expression of conditioned opiate withdrawal in rats. Neuropsychopharmacology. 1998 Nov; 19(5):406-16.
Schulteis G, Stinus L, Risbrough VB, Koob GF. PMID: 9778662.
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PubMed Mentions:
12 Fields:
Translation:
Animals
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Anxiogenic-like effects of spontaneous and naloxone-precipitated opiate withdrawal in the elevated plus-maze. Pharmacol Biochem Behav. 1998 Jul; 60(3):727-31.
Schulteis G, Yackey M, Risbrough V, Koob GF. PMID: 9678657.
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PubMed Mentions:
40 Fields:
Translation:
Animals
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Interactions between a novel cholinergic ion channel agonist, SIB-1765F and L-DOPA in the reserpine model of Parkinson's disease in rats. J Pharmacol Exp Ther. 1997 Jan; 280(1):393-401.
Menzaghi F, Whelan KT, Risbrough VB, Rao TS, Lloyd GK. PMID: 8996220.
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PubMed Mentions:
6 Fields:
Translation:
Animals
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Effects of a novel cholinergic ion channel agonist SIB-1765F on locomotor activity in rats. J Pharmacol Exp Ther. 1997 Jan; 280(1):384-92.
Menzaghi F, Whelan KT, Risbrough VB, Rao TS, Lloyd GK. PMID: 8996219.
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PubMed Mentions:
5 Fields:
Translation:
Animals