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David Braff

Title(s)Recall Faculty, Psychiatry
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Biography

    David Braff, M.D. is Distinguished Professor of Psychiatry, and Director of the Schizophrenia Program at the University of California, San Diego, School of Medicine. He is also Director of the NIH-funded Consortium on the Genetics of Schizophrenia (COGS). He trained at the University of Pennsylvania, Yale University, and the University of California, San Francisco.

    Research Interests

    David Braff, M.D. is Distinguished Professor of Psychiatry, and Director of the Schizophrenia Program at the Department of Psychiatry, University of California San Diego School of Medicine. He is also Director and Lead Scientist of the NIH-funded multi-site Consortium on the Genetics of Schizophrenia (COGS). He trained at the University of Pennsylvania, Yale University, and the University of California, San Francisco.

    David Braff’s research interests have received long-term NIMH and NARSAD Distinguished Investigator funding and a special NIMH MERIT Award to extend his research as well as funding from the Veterans Administration. His interests center around 1) the identification of neurocognitive and neurophysiological biomarker deficits in psychiatric disorders (with an emphasis on schizophrenia); 2) understanding the neural circuit/substrate dysfunctions of schizophrenia patients using human and cross-species translational animal model studies; 3) using neurocognitive, imaging, information processing, and attentional dysregulation as endophenotypes in family/genetic studies; 4) utilizing translational and genetic research tools to identify the neural circuit basis and the genetic architecture of neuropsychiatric disorders such as schizophrenia; and 5) utilizing genetically and behaviorally determined, strong inference-based targets for developing efficacious antipsychotic medications and psychosocial therapies that can improve the functional outcome and quality of life of schizophrenia patients and reduce the devastating disease burden placed on them and their families by this “no fault” clinical brain disorder.

    David Braff has published over 250 articles and 300 reviews, book chapters and abstracts. He has received special recognition from the Institute for Scientific Information (ISI) as being in the top half of 1% of most highly cited neuropsychiatric researchers. In addition, he has been the Attending Physician for over 10,000 patients with schizophrenia and other serious mental disorders, and has trained many researchers and clinicians. Dr. Braff has served as Councilor, Executive Secretary and President of the Society of Biological Psychiatry (SOBP), and as a Councilor and President of the American College of Neuropsychopharmacology (ACNP), 2 world leading neuropsychiatric research societies. He has consulted to the Diagnostic and Statistical Manual (DSM IV and V) Committee of the APA, and Expert Treatment Committee of the American Psychiatric Association (APA). He is the Co-Chair of the Executive Committee and Director of the Clinical Neurosciences and Genomic Unit at the Veterans Administration VISN 22 Mental Illness, Research and Clinical Center (MIRECC) program in the Southwest United States which investigates psychosis and its treatment. He has also been a key figure in advancing the Mission of the International Congress on Schizophrenia Research (ICOSR) and liaisoned USA-Russia and USA-China cultural and grant cooperative projects. He served for 15 years as President of the campus-wide UCSD Faculty Association.

    David Braff has received numerous Grants, Awards, and Prizes. A Fellow of the American Psychiatric Association (APA), Dr. Braff received the Kempf Research Prize and Marmor Award for excellence in biopsychosocial research from the APA, as well as the Gold Medal for lifetime research accomplishments from the SOBP, and the Warren Award for schizophrenia research from the ICOSR. He received the George Thompson Award from the SOBP for service to the field, the Dean Award for Schizophrenia Research Excellence from the American College of Psychiatrists (ACP) as well as Gold Medal for psychiatric research from Society of Biological Psychiatry with other awards. He has been selected by his peers as one of the “Best Doctors” in the United States and in San Diego. He serves on many national and international committees and societies, such as the Executive Committee of the MATRICS Project of the NIMH, which identified novel cognitive targets for antipsychotic medications, and other NIMH advisory committees that focus on issues such as the design and conduct of large clinical treatment trials. Dr. Braff is on the Editorial Boards of the Archives of General Psychiatry and five other journals and reviews manuscripts for over 20 Top Journals. He has lectured nationally and internationally on many topics in neuropsychiatric science and practice, and is recognized as a leader of the international neuropsychiatric community.

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    Collapse research activities and funding
    2/5-Gentics of Transcriptional Endophenotypes for Schizophrenia
    NIH R01MH093533Apr 15, 2012 - Mar 31, 2017
    Role: Principal Investigator
    5/5:Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia
    NIH RC2MH089984Sep 30, 2009 - Aug 31, 2011
    Role: Principal Investigator
    4/4-A Genomic Approach to Schizophrenia
    NIH R01MH084071Apr 16, 2009 - Jan 31, 2014
    Role: Principal Investigator
    5/5: A Genome-wide Methylation Scan for Epigenetic Contributions to Schizophrenia
    NIH U01MH085265Sep 30, 2008 - May 31, 2014
    Role: Principal Investigator
    1/6-The Genetics of Endophenotypes and Schizophrenia
    NIH R01MH065571Apr 4, 2003 - Jan 31, 2016
    Role: Principal Investigator
    Gating and Inhibiting in Schizophrenia
    NIH R01MH042228Jan 1, 1987 - Apr 30, 2017
    Role: Principal Investigator
    SENSORY GATING AND HABITUATION IN SCHIZOPHRENIA
    NIH R37MH042228Jan 1, 1987 - Apr 16, 2003
    Role: Principal Investigator
    General Clinical Research Center
    NIH M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Biological insights into schizophrenia from ancestrally diverse populations. Nature. 2026 03; 651(8105):404-413. Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Natarajan S, Francis MO, Rajeevan N, Cheung KH, Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS), Consortium on the Genomics of Schizophrenia (COGS), Genomic Psychiatry Cohort (GPC) Investigators, DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley PF, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN, PsychAD Consortium, VA Cooperative Studies Program (CSP) #572, VA Million Veteran Program (MVP), Huang GD, Muralidhar S, Gaziano JM, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. PMID: 41565822.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    2. Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia. HGG Adv. 2026 Jan 15; 7(1):100499. Li R, Gagliano Taliun SA, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Wang J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA, National Heart, Lung, and Blood Institute Trans-Omics for Precision Medicine (TOPMed) Consortium, Genomic Psychiatry Cohort Investigators, Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll SA, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ. PMID: 40886051; PMCID: PMC12494821.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects. medRxiv. 2025 Jul 16. Engchuan W, Shanta O, Kumar K, MacDonald JR, Thiruvahindrapuram B, Hamdan O, Klein M, Maihofer A, Guevara J, Hong O, Huguet G, Sacks M, Ahangari M, Feitosa RMMW, Han K, Mendes M, Zhou X, Bautista NX, Pellecchia G, Wang Z, Merico D, Yuen RKC, Trost B, Sønderby I, Adams MJ, Adolfsson R, Agartz I, Aiello AE, Alda M, Allardyce J, Amstadter AB, Andlauer TFM, Andreassen OA, Artigas MS, Austin SB, Ayub M, Baker DG, Bass N, Baune BT, Bayas M, Berger K, Biernacka JM, Bigdeli T, Bisson JI, Blackwood D, Boks M, Braff D, Bramon E, Breen G, Brueckl T, Bryant RA, Bulik CM, Buxbaum J, Cairns MJ, Caldas-de-Almeida JM, Campbell M, Campion D, Carr VJ, Castelao E, Chaumette B, Cichon S, Cohen D, Corvin A, Craddock N, Crosbie J, Czamara D, Dannlowski U, Degenhardt F, Delahanty DL, Dempfle A, Desachy G, Di Florio A, Dickerson FB, Djurovic S, Domschke K, Douglas L, Drange OK, Duncan LE, Edenberg HJ, Esko T, Faraone S, Feeny NC, Forstner AJ, Franke B, Frye M, Fu DJ, Fullerton JM, Gareeva A, Garvert L, Gatt JM, Gejman P, Geschwind DH, Giegling I, Glatt SJ, Glessner J, Goes FS, Gordon-Smith K, Grabe H, Green MJ, Green MF, Greenwood T, Grigoroiu-Serbanescu M, Gur RE, Gur RC, Guzman-Parra J, Haavik J, Hahn T, Hakonarson H, Hallmayer J, Hamshere ML, Hartmann AM, Hassan A, Hayward C, Hebebrand J, Hemmings SMJ, Herms S, Herrera-Rivero M, Hinney A, Homuth G, Ingason A, Ito LT, Iwata N, Jones I, Jones LA, Jonsson L, Jönsson EG, Kahn RS, Karlsson R, Kaufman ML, Kelsoe JR, Kennedy JL, King A, Kircher T, Kirov G, Knappskog P, Knowles JA, Kobayashi N, Koenen KC, Konte B, Korgaonkar M, Kowalec K, Krebs MO, Landén M, Laurent-Levinson C, Lebois LA, Levinson D, Lewis C, Li Q, Liberzon I, Light G, Loo SK, Lu Y, Lucae S, Marmar C, Martin NG, Mayoral F, McIntosh AM, McLaughlin KA, McLean SA, McQuillin A, Medland SE, Meyer-Lindenberg A, Milanova V, Mitchell PB, Molina E, Mowry B, Muller-Myhsok B, Mullins N, Murray R, Nöthen MM, Nurnberger JI, O'Connell KS, Ophoff RA, Orcutt HK, Owen MJ, Palotie A, Pato C, Pato M, Pawlak J, Peters T, Petryshen TL, Pistis G, Potash JB, Powell J, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ressler KJ, Ribasés M, Rietschel M, Risbrough VB, Rivera M, Rothbaum AO, Rothbaum BO, Rujescu D, Saito T, Sanders AR, Schachar RJ, Schofield PR, Schulte EC, Schulze TG, Scott LJ, Seedat S, Sheerin C, Shi J, Sklar P, Smalley S, Smeland OB, Smoller JW, Sonuga-Barke E, Clair DS, Steen NE, Stein D, Stein F, Stein MB, Streit F, Swerdlow N, Thibaut F, Thygesen JH, Timerbulatov I, Toma C, Trapido E, Tremblay M, Tsuang MT, Uddin M, Vawter MP, Vincent JB, Völzke H, Walters JT, Weickert CS, Weiss LA, Weissman MM, Werge T, Witt SH, Xavier M, Yolken R, Young RM, Zayats T, Zoellner LA, AGP Consortium, PEIC Psychosis Endophenotypes International Consortium, ADHD Working Group of the Psychiatric Genomics Consortium, Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the P, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, PTSD Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, et al. PMID: 40791676; PMCID: PMC12338884.
      View in: PubMed   Mentions:
    4. A cross-disorder analysis of CNVs finds novel loci and dose-dependent relationships of genes to psychiatric traits. medRxiv. 2025 Jul 16. Shanta O, Klein M, Sacks M, MacDonald JR, Maihofer A, Ahangari M, Engchuan W, Thiruvahindrapuram B, Guevara J, Hong O, Huguet G, Sønderby I, Kalyuzhny M, Adams MJ, Adolfsson R, Agartz I, Aiello AE, Alda M, Allardyce J, Amstadter AB, Andlauer TFM, Andreassen OA, Artigas MS, Austin SB, Ayub M, Baker DG, Bass N, Baune BT, Bayas M, Berger K, Biernacka JM, Bigdeli T, Bisson JI, Blackwood D, Boks M, Braff D, Bramon E, Breen G, Brueckl T, Bryant RA, Bulik CM, Buxbaum J, Cairns MJ, Caldas-de-Almeida JM, Campbell M, Campion D, Carr VJ, Castelao E, Chaumette B, Cichon S, Cohen D, Corvin A, Craddock N, Crosbie J, Czamara D, Dannlowski U, Degenhardt F, Delahanty DL, Dempfle A, Desachy G, Di Florio A, Dickerson FB, Djurovic S, Domschke K, Douglas L, Drange OK, Duncan LE, Edenberg HJ, Esko T, Faraone S, Feeny NC, Forstner AJ, Franke B, Frye M, Fu DJ, Fullerton JM, Gareeva A, Garvert L, Gatt JM, Gejman P, Geschwind DH, Giegling I, Glatt SJ, Glessner J, Goes FS, Gordon-Smith K, Grabe H, Green MJ, Green MF, Greenwood T, Grigoroiu-Serbanescu M, Gur RE, Gur RC, Guzman-Parra J, Haavik J, Hahn T, Hakonarson H, Hallmayer J, Hamshere ML, Hartmann AM, Hassan A, Hayward C, Hebebrand J, Hemmings SMJ, Herms S, Herrera-Rivero M, Hinney A, Homuth G, Ingason A, Ito LT, Iwata N, Jones I, Jones LA, Jonsson L, Jönsson EG, Kahn RS, Karlsson R, Kaufman ML, Kelsoe JR, Kennedy JL, King A, Kircher T, Kirov G, Knappskog P, Knowles JA, Kobayashi N, Koenen KC, Konte B, Korgaonkar M, Kowalec K, Krebs MO, Landén M, Laurent-Levinson C, Lebois LA, Levinson D, Lewis C, Li Q, Liberzon I, Light G, Loo SK, Lu Y, Lucae S, Marmar C, Martin NG, Mayoral F, McIntosh AM, McLaughlin KA, McLean SA, McQuillin A, Medland SE, Meyer-Lindenberg A, Milanova V, Mitchell PB, Molina E, Mowry B, Muller-Myhsok B, Mullins N, Murray R, Nöthen MM, Nurnberger JI, O'Connell KS, Ophoff RA, Orcutt HK, Owen MJ, Palotie A, Pato C, Pato M, Pawlak J, Peters T, Petryshen TL, Pistis G, Potash JB, Powell J, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ressler KJ, Ribasés M, Rietschel M, Risbrough VB, Rivera M, Rothbaum AO, Rothbaum BO, Rujescu D, Saito T, Sanders AR, Schachar RJ, Schofield PR, Schulte EC, Schulze TG, Scott LJ, Seedat S, Sheerin C, Shi J, Sklar P, Smalley S, Smeland OB, Smoller JW, Sonuga-Barke E, Clair DS, Steen NE, Stein D, Stein F, Stein MB, Streit F, Swerdlow N, Thibaut F, Thygesen JH, Timerbulatov I, Toma C, Trapido E, Tremblay M, Tsuang MT, Uddin M, Vawter MP, Vincent JB, Völzke H, Walters JT, Weickert CS, Weiss LA, Weissman MM, Werge T, Witt SH, Xavier M, Yolken R, Young RM, Zayats T, Zoellner LA, AGP Consortium, PEIC Psychosis Endophenotypes International Consortium, ADHD Working Group of the Psychiatric Genomics Consortium, Autism Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, PTSD Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, CNV Working Group of the Psychiatric Genomics Consortium, Kendall K, et al. PMID: 40791719; PMCID: PMC12338896.
      View in: PubMed   Mentions:
    5. Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia. medRxiv. 2025 Feb 19. Li R, Taliun SAG, Liao K, Flickinger M, Sobell JL, Genovese G, Locke AE, Chiu RR, LeFaive J, Wang J, Martins T, Chapman S, Neumann A, Handsaker RE, Arnett DK, Barnes KC, Boerwinkle E, Braff D, Cade BE, Fornage M, Gibbs RA, Hoth KF, Hou L, Kooperberg C, Loos RJF, Metcalf GA, Montgomery CG, Morrison AC, Qin ZS, Redline S, Reiner AP, Rich SS, Rotter JI, Taylor KD, Viaud-Martinez KA, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Genomic Psychiatry Cohort investigators, Bigdeli TB, Gabriel S, Zollner S, Smith AV, Abecasis G, McCarroll S, Pato MT, Pato CN, Boehnke M, Knowles J, Kang HM, Ophoff RA, Ernst J, Scott LJ. PMID: 39763555; PMCID: PMC11703280.
      View in: PubMed   Mentions:
    6. Biological Insights from Schizophrenia-associated Loci in Ancestral Populations. medRxiv. 2024 Aug 28. Bigdeli TB, Chatzinakos C, Bendl J, Barr PB, Venkatesh S, Gorman BR, Clarence T, Genovese G, Iyegbe CO, Peterson RE, Kolokotronis SO, Burstein D, Meyers JL, Li Y, Rajeevan N, Sayward F, Cheung KH, Project Among African-Americans to Explore Risks for Schizophrenia (PAARTNERS), Consortium on the Genomics of Schizophrenia (COGS), Genomic Psychiatry Cohort (GPC) Investigators, DeLisi LE, Kosten TR, Zhao H, Achtyes E, Buckley P, Malaspina D, Lehrer D, Rapaport MH, Braff DL, Pato MT, Fanous AH, Pato CN, PsychAD Consortium, Cooperative Studies Program (CSP) #572, Million Veteran Program (MVP), Huang GD, Muralidhar S, Michael Gaziano J, Pyarajan S, Girdhar K, Lee D, Hoffman GE, Aslan M, Fullard JF, Voloudakis G, Harvey PD, Roussos P. PMID: 39252912; PMCID: PMC11383513.
      View in: PubMed   Mentions:
    7. Novel N100 area reliably captures aberrant sensory processing and is associated with neurocognition in early psychosis. Schizophr Res. 2024 09; 271:71-80. Machiraju SN, Wyss J, Light G, Braff DL, Cadenhead KS. PMID: 39013347.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Clarifying directional dependence among measures of early auditory processing and cognition in schizophrenia: leveraging Gaussian graphical models and Bayesian networks. Psychol Med. 2024 Jul; 54(9):1930-1939. Abplanalp SJ, Braff DL, Light GA, Joshi YB, Nuechterlein KH, Green MF, Consortium on the Genetics of Schizophrenia. PMID: 38287656; PMCID: PMC11413352.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    9. GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors. Am J Psychiatry. 2023 10 01; 180(10):723-738. Docherty AR, Mullins N, Ashley-Koch AE, Qin X, Coleman JRI, Shabalin A, Kang J, Murnyak B, Wendt F, Adams M, Campos AI, DiBlasi E, Fullerton JM, Kranzler HR, Bakian AV, Monson ET, Rentería ME, Walss-Bass C, Andreassen OA, Behera C, Bulik CM, Edenberg HJ, Kessler RC, Mann JJ, Nurnberger JI, Pistis G, Streit F, Ursano RJ, Polimanti R, Dennis M, Garrett M, Hair L, Harvey P, Hauser ER, Hauser MA, Huffman J, Jacobson D, Madduri R, McMahon B, Oslin DW, Trafton J, Awasthi S, Berrettini WH, Bohus M, Chang X, Chen HC, Chen WJ, Christensen ED, Crow S, Duriez P, Edwards AC, Fernández-Aranda F, Galfalvy H, Gandal M, Gorwood P, Guo Y, Hafferty JD, Hakonarson H, Halmi KA, Hishimoto A, Jain S, Jamain S, Jiménez-Murcia S, Johnson C, Kaplan AS, Kaye WH, Keel PK, Kennedy JL, Kim M, Klump KL, Levey DF, Li D, Liao SC, Lieb K, Lilenfeld L, Marshall CR, Mitchell JE, Okazaki S, Otsuka I, Pinto D, Powers A, Ramoz N, Ripke S, Roepke S, Rozanov V, Scherer SW, Schmahl C, Sokolowski M, Starnawska A, Strober M, Su MH, Thornton LM, Treasure J, Ware EB, Watson HJ, Witt SH, Woodside DB, Yilmaz Z, Zillich L, Adolfsson R, Agartz I, Alda M, Alfredsson L, Appadurai V, Artigas MS, Van der Auwera S, Azevedo MH, Bass N, Bau CHD, Baune BT, Bellivier F, Berger K, Biernacka JM, Bigdeli TB, Binder EB, Boehnke M, Boks MP, Braff DL, Bryant R, Budde M, Byrne EM, Cahn W, Castelao E, Cervilla JA, Chaumette B, Corvin A, Craddock N, Djurovic S, Foo JC, Forstner AJ, Frye M, Gatt JM, Giegling I, Grabe HJ, Green MJ, Grevet EH, Grigoroiu-Serbanescu M, Gutierrez B, Guzman-Parra J, Hamshere ML, Hartmann AM, Hauser J, Heilmann-Heimbach S, Hoffmann P, Ising M, Jones I, Jones LA, Jonsson L, Kahn RS, Kelsoe JR, Kendler KS, Kloiber S, Koenen KC, Kogevinas M, Krebs MO, Landén M, Leboyer M, Lee PH, Levinson DF, Liao C, Lissowska J, Mayoral F, McElroy SL, McGrath P, McGuffin P, McQuillin A, Mehta D, Melle I, Mitchell PB, Molina E, Morken G, Nievergelt C, Nöthen MM, O'Donovan MC, Ophoff RA, Owen MJ, Pato C, Pato MT, Penninx BWJH, Potash JB, Power RA, Preisig M, Quested D, Ramos-Quiroga JA, Reif A, Ribasés M, Richarte V, Rietschel M, Rivera M, Roberts A, Roberts G, Rouleau GA, Rovaris DL, Sanders AR, Schofield PR, Schulze TG, Scott LJ, Serretti A, Shi J, Sirignano L, Sklar P, Smeland OB, Smoller JW, Sonuga-Barke EJS, Trzaskowski M, Tsuang MT, Turecki G, Vilar-Ribó L, Vincent JB, Völzke H, Walters JTR, Weickert CS, Weickert TW, Weissman MM, Williams LM, Wray NR, Zai CC, Agerbo E, Børglum AD, Breen G, Demontis D, Erlangsen A, Gelernter J, Glatt SJ, Hougaard DM, Hwu HG, Kuo PH, Lewis CM, Li QS, Liu CM, Martin NG, McIntosh AM, Medland SE, Mors O, Nordentoft M, Olsen CM, Porteous D, Smith DJ, Stahl EA, Stein MB, Wasserman D, Werge T, Whiteman DC, Willour V, VA Million Veteran Program (MVP), MVP Suicide Exemplar Workgroup, Suicide Working Group of the Psychiatric Genomics Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Eating Disorder Working Group of the Psychiatric Genomics Consortium, German Borderline Genomics Consortium, Coon H, Beckham JC, Kimbrel NA, Ruderfer DM. PMID: 37777856; PMCID: PMC10603363.
      View in: PubMed   Mentions: 72     Fields:    Translation:Humans
    10. Sensitivity of Schizophrenia Endophenotype Biomarkers to Anticholinergic Medication Burden. Am J Psychiatry. 2023 07 01; 180(7):519-523. Joshi YB, Molina JL, Braff DL, Green MF, Gur RC, Gur RE, Nuechterlein KH, Stone WS, Greenwood TA, Lazzeroni LC, Radant AD, Silverman JM, Sprock J, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Swerdlow NR, Light GA. PMID: 37038743.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    11. Ultrarare Coding Variants and Cognitive Function in Schizophrenia-Unraveling the Enduring Mysteries of Neuropsychiatric Genetics. JAMA Psychiatry. 2022 10 01; 79(10):946-948. Braff DL, Bigdeli TB. PMID: 35976678.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    12. Understanding Connections and Boundaries Between Positive Symptoms, Negative Symptoms, and Role Functioning Among Individuals With Schizophrenia: A Network Psychometric Approach. JAMA Psychiatry. 2022 10 01; 79(10):1014-1022. Abplanalp SJ, Braff DL, Light GA, Nuechterlein KH, Green MF, Consortium on the Genetics of Schizophrenia-2. PMID: 35976655; PMCID: PMC9386606.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
    13. Extent to which array genotyping and imputation with large reference panels approximate deep whole-genome sequencing. Am J Hum Genet. 2022 09 01; 109(9):1653-1666. Hanks SC, Forer L, Schönherr S, LeFaive J, Martins T, Welch R, Gagliano Taliun SA, Braff D, Johnsen JM, Kenny EE, Konkle BA, Laakso M, Loos RFJ, McCarroll S, Pato C, Pato MT, Smith AV, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Boehnke M, Scott LJ, Fuchsberger C. PMID: 35981533; PMCID: PMC9502057.
      View in: PubMed   Mentions: 20     Fields:    Translation:Humans
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    101. Preattentive sensory processing as indexed by the MMN and P3a brain responses is associated with cognitive and psychosocial functioning in healthy adults. J Cogn Neurosci. 2007 Oct; 19(10):1624-32. Light GA, Swerdlow NR, Braff DL. PMID: 18271737; PMCID: PMC2562660.
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    102. Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: a double-blind, randomized controlled trial. Schizophr Res. 2007 Sep; 95(1-3):134-42. Wynn JK, Green MF, Sprock J, Light GA, Widmark C, Reist C, Erhart S, Marder SR, Mintz J, Braff DL. PMID: 17662577; PMCID: PMC2716219.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    103. Cognitive, neurophysiological, and functional correlates of proverb interpretation abnormalities in schizophrenia. J Int Neuropsychol Soc. 2007 Jul; 13(4):653-63. Kiang M, Light GA, Prugh J, Coulson S, Braff DL, Kutas M. PMID: 17521483.
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    104. Endophenotyping schizophrenia. Am J Psychiatry. 2007 May; 164(5):705-7. Braff D, Schork NJ, Gottesman II. PMID: 17475726.
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    105. Electrophysiological insights into conceptual disorganization in schizophrenia. Schizophr Res. 2007 May; 92(1-3):225-36. Kiang M, Kutas M, Light GA, Braff DL. PMID: 17383161; PMCID: PMC3974604.
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    106. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2007 May; 92(1-3):237-51. Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 17346930; PMCID: PMC2039885.
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    107. Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients. Biol Psychiatry. 2007 May 15; 61(10):1204-7. Braff DL, Light GA, Swerdlow NR. PMID: 17161386.
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    108. Social cognition in schizophrenia: relationships with neurocognition and negative symptoms. Schizophr Res. 2007 Feb; 90(1-3):316-24. Sergi MJ, Rassovsky Y, Widmark C, Reist C, Erhart S, Braff DL, Marder SR, Green MF. PMID: 17141477.
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    109. Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch Gen Psychiatry. 2006 Dec; 63(12):1325-35. Swerdlow NR, Light GA, Cadenhead KS, Sprock J, Hsieh MH, Braff DL. PMID: 17146007.
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    110. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophr Bull. 2007 Jan; 33(1):21-32. Braff DL, Freedman R, Schork NJ, Gottesman II. PMID: 17088422; PMCID: PMC2632293.
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    111. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull. 2007 Jan; 33(1):33-48. Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 17035358; PMCID: PMC2632302.
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    112. Statistical genetics concepts and approaches in schizophrenia and related neuropsychiatric research. Schizophr Bull. 2007 Jan; 33(1):95-104. Schork NJ, Greenwood TA, Braff DL. PMID: 17035359; PMCID: PMC2632283.
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    113. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res. 2007 Jan; 89(1-3):320-9. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. PMID: 17023145.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    114. The neural correlates of habituation of response to startling tactile stimuli presented in a functional magnetic resonance imaging environment. Psychiatry Res. 2006 Nov 22; 148(1):1-10. McDowell JE, Brown GG, Lazar N, Camchong J, Sharp R, Krebs-Thomson K, Eyler LT, Braff DL, Geyer MA. PMID: 17000088.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    115. Gamma band oscillations reveal neural network cortical coherence dysfunction in schizophrenia patients. Biol Psychiatry. 2006 Dec 01; 60(11):1231-40. Light GA, Hsu JL, Hsieh MH, Meyer-Gomes K, Sprock J, Swerdlow NR, Braff DL. PMID: 16893524.
      View in: PubMed   Mentions: 208     Fields:    Translation:Humans
    116. Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology. 2006 Mar; 31(3):506-15. Swerdlow NR, Geyer MA, Shoemaker JM, Light GA, Braff DL, Stevens KE, Sharp R, Breier M, Neary A, Auerbach PP. PMID: 16123772; PMCID: PMC1373667.
      View in: PubMed   Mentions: 19     Fields:    Translation:Animals
    117. Prepulse-elicited motor reactions do not differ between schizophrenia patients and control subjects. Behav Neurosci. 2006 Feb; 120(1):224-7. Swerdlow NR, Sprock J, Braff DL. PMID: 16492135.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    118. Effects of background and prepulse characteristics on prepulse inhibition and facilitation: implications for neuropsychiatric research. Biol Psychiatry. 2006 Mar 15; 59(6):555-9. Hsieh MH, Swerdlow NR, Braff DL. PMID: 16169529.
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    119. Stability of mismatch negativity deficits and their relationship to functional impairments in chronic schizophrenia. Am J Psychiatry. 2005 Sep; 162(9):1741-3. Light GA, Braff DL. PMID: 16135637.
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    120. P50 suppression in individuals at risk for schizophrenia: the convergence of clinical, familial, and vulnerability marker risk assessment. Biol Psychiatry. 2005 Jun 15; 57(12):1504-9. Cadenhead KS, Light GA, Shafer KM, Braff DL. PMID: 15953486.
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    121. On the waveform of the acoustic startle blink in the paradigm of prepulse inhibition - methodological and physiological aspects. Neuropsychobiology. 2005; 52(1):24-7. Meincke U, Light GA, Geyer MA, Braff DL. PMID: 15942260.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    122. Prepulse inhibition of perceived stimulus intensity: paradigm assessment. Biol Psychol. 2005 May; 69(2):133-47. Swerdlow NR, Stephany NL, Talledo J, Light G, Braff DL, Baeyens D, Auerbach PP. PMID: 15804542.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    123. Female schizophrenia patients have prepulse inhibition deficits. Biol Psychiatry. 2005 Apr 01; 57(7):817-20. Braff DL, Light GA, Ellwanger J, Sprock J, Swerdlow NR. PMID: 15820241.
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    124. Startle modulation in Caucasian-Americans and Asian-Americans: a prelude to genetic/endophenotypic studies across the 'Pacific Rim'. Psychiatr Genet. 2005 Mar; 15(1):61-5. Swerdlow NR, Talledo JA, Braff DL. PMID: 15722959.
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    125. Mismatch negativity deficits are associated with poor functioning in schizophrenia patients. Arch Gen Psychiatry. 2005 Feb; 62(2):127-36. Light GA, Braff DL. PMID: 15699289.
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    126. The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia. Dialogues Clin Neurosci. 2005; 7(2):125-35. Braff DL, Light GA. PMID: 16262208; PMCID: PMC3181726.
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    127. Preattentional and attentional cognitive deficits as targets for treating schizophrenia. Psychopharmacology (Berl). 2004 Jun; 174(1):75-85. Braff DL, Light GA. PMID: 15118804.
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    128. Sensitization and habituation of the acoustic startle reflex in patients with schizophrenia. Psychiatry Res. 2004 Apr 15; 126(1):51-61. Meincke U, Light GA, Geyer MA, Braff DL, Gouzoulis-Mayfrank E. PMID: 15081627.
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    129. The value of referring to recently introduced antipsychotics as "second generation". Am J Psychiatry. 2003 Aug; 160(8):1371-2. Lohr JB, Braff DL. PMID: 12900294.
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    130. Visual masking as a probe for abnormal gamma range activity in schizophrenia. Biol Psychiatry. 2003 Jun 15; 53(12):1113-9. Green MF, Mintz J, Salveson D, Nuechterlein KH, Breitmeyer B, Light GA, Braff DL. PMID: 12814862.
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    131. The relationship of age to prepulse inhibition and habituation of the acoustic startle response. Biol Psychol. 2003 Mar; 62(3):175-95. Ellwanger J, Geyer MA, Braff DL. PMID: 12633977.
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    132. Some possible genetic parallels across alcoholism, bipolar disorder and schizophrenia. J Stud Alcohol. 2003 Mar; 64(2):157-9. Schuckit MA, Kelsoe JR, Braff DL, Wilhelmsen KC. PMID: 12713187.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    133. The use of the Ego Impairment Index across the schizophrenia spectrum. J Pers Assess. 2003 Feb; 80(1):50-7. Perry W, Minassian A, Cadenhead K, Sprock J, Braff D. PMID: 12584067.
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    134. Chaos and schizophrenia: does the method fit the madness? Biol Psychiatry. 2003 Jan 01; 53(1):3-11. Paulus MP, Braff DL. PMID: 12513940.
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    135. Schizophrenia subjects show intact success-related neural activation but impaired uncertainty processing during decision-making. Neuropsychopharmacology. 2003 Apr; 28(4):795-806. Paulus MP, Frank L, Brown GG, Braff DL. PMID: 12655327.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    136. Information processing deficits in acutely psychotic schizophrenia patients medicated and unmedicated at the time of admission. Am J Psychiatry. 2002 Aug; 159(8):1375-81. Perry W, Feifel D, Minassian A, Bhattacharjie I, Braff DL. PMID: 12153831.
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    137. Parietal dysfunction is associated with increased outcome-related decision-making in schizophrenia patients. Biol Psychiatry. 2002 Jun 15; 51(12):995-1004. Paulus MP, Hozack NE, Zauscher BE, Frank L, Brown GG, McDowell J, Braff DL. PMID: 12062884.
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    138. Neurobiological measures of schizotypal personality disorder: defining an inhibitory endophenotype? Am J Psychiatry. 2002 May; 159(5):869-71. Cadenhead KS, Light GA, Geyer MA, McDowell JE, Braff DL. PMID: 11986147.
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    139. Endophenotyping schizotypy: a prelude to genetic studies within the schizophrenia spectrum. Schizophr Res. 2002 Mar 01; 54(1-2):47-57. Cadenhead KS, Braff DL. PMID: 11853978.
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    140. Neural correlates of refixation saccades and antisaccades in normal and schizophrenia subjects. Biol Psychiatry. 2002 Feb 01; 51(3):216-23. McDowell JE, Brown GG, Paulus M, Martinez A, Stewart SE, Dubowitz DJ, Braff DL. PMID: 11839364.
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    141. Behavioral and functional neuroimaging evidence for prefrontal dysfunction in methamphetamine-dependent subjects. Neuropsychopharmacology. 2002 Jan; 26(1):53-63. Paulus MP, Hozack NE, Zauscher BE, Frank L, Brown GG, Braff DL, Schuckit MA. PMID: 11751032.
      View in: PubMed   Mentions: 130     Fields:    Translation:HumansCTClinical Trials
    142. Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology (Berl). 2001 Jul; 156(2-3):234-58. Braff DL, Geyer MA, Swerdlow NR. PMID: 11549226.
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    143. Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res. 2001 Apr 15; 49(1-2):171-8. Braff DL, Geyer MA, Light GA, Sprock J, Perry W, Cadenhead KS, Swerdlow NR. PMID: 11343875.
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    144. Symptom correlates of prepulse inhibition deficits in male schizophrenic patients. Am J Psychiatry. 1999 Apr; 156(4):596-602. Braff DL, Swerdlow NR, Geyer MA. PMID: 10200740.
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    145. Hemispheric and attentional contributions to perceptual organization deficits on the global-local task in schizophrenia. Neuropsychology. 1999 Apr; 13(2):271-281. Granholm E, Perry W, Filoteo JV, Braff D. PMID: 10353376.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCTClinical Trials
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