Gregory Light

Title(s)Professor, Psychiatry
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0003-4730-8646 Additional info
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    Other Positions
    Title(s)Vice Chair, Psychiatry Education and Training


    Collapse Biography 
    Collapse Awards and Honors
    Brain & Behavior Research Foundation2021Top Advancement & Breakthrough 2021
    Brain & Behavior Research Foundation2018Top Advancement & Breakthrough of 2018
    UC San Diego Faculty Mentor Program2015Outstanding Mentor Award
    Brain & Behavior Research Foundation2014Sidney R. Baer, Jr. International Prize for Innovative and Promising Schizophrenia Research

    Collapse Overview 
    Collapse Overview
    Dr. Gregory Light is a Professor and Vice Chair of Education and Training in the UCSD Department of Psychiatry. Dr. Light also serves as the Director of Mental Health Research and the Director of the Mental Illness, Research, Education and Clinical Center (MIRECC) at the VA San Diego Healthcare System. In these roles, he provide leadership, supervision, and administrative support across several clinical, education, and multidisciplinary research programs. Dr. Light has published over 175 peer-reviewed papers (h-index=63). This work has been prominently featured in policy reports from the Institute of Medicine for next-generation strategies for personalized treatments of psychotic disorders.

    Psychotic disorders have devastating and often life-long consequences for approximately 2% of the global population. Most psychiatric interventions are implemented in the absence of knowledge about individual variation in important domains of brain function that might influence therapeutic response and outcome. This “one-size-fits-all” approach to treatment is problematic, with treatment failure occurring far too often and incurring substantial cost to the patient, family, therapist and larger social system. To “bend the curve” on the individual outcomes and societal impact of chronic psychotic illness, we must advance our understanding of the neural substrates of the illness features that most strongly contribute to poor outcomes, and use this information to guide mechanistically informed, personalized treatments. Dr. Light's program of research has advanced the use of neurophysiological biomarkers to develop precision medicine trials for psychosis patients that are: 1) effectively delivered in “real-world” community centers; and 2) informed by objective, reliable, validated, and low-cost biomarkers for identifying patients most likely to benefit (or not) from treatments. Findings support large-scale biomarker-guided trials to prevent or ameliorate illness in high-risk cohorts or treatment refractory populations. This program ultimately aims to develop and apply personalized biomarker assessment tools to deliver the “right treatment” to the “right person” at the “right time.”

    Dr. Light's career has also maintained a focus on developing scientists for careers in academic medicine and neuroscience. As Vice Chair of Psychiatry Education and Training in the UCSD Department of Psychiatry, Dr.Light assists in the oversight of over 25 Programs. As Center Director of the Mental Illness, Research, Education, and Clinical Center (MIRECC) at the VA San Diego Healthcare System, he oversees 2 post-doctoral fellowship programs and coordinates the activities of trainees at many levels. Dr. Light also provides frequent lectures and serves on independent study, thesis, and dissertation committees across departments at UCSD including: Psychiatry, Psychology, Neuroscience, Cognitive Science, and Biology.

    Collapse Research 
    Collapse Research Activities and Funding
    Memantine augmentation of cognitive training in schizophrenia
    NIH R33MH125114Feb 16, 2021 - Dec 31, 2023
    Role: Principal Investigator
    Accelerated Inflammaging in Schizophrenia
    NIH R01MH094151May 1, 2012 - Feb 28, 2022
    Role: Principal Investigator
    Pathway(s) From Genes to Functional Deficits of Schizophrenia Patients
    NIH R01MH079777Jul 25, 2007 - May 31, 2013
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Featured Content 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mismatch Negativity as an Index of Auditory Short-Term Plasticity: Associations with Cortisol, Inflammation, and Gray Matter Volume in Youth at Clinical High Risk for Psychosis. Clin EEG Neurosci. 2024 Nov 18; 15500594241294035. Hamilton HK, Roach BJ, Bachman PM, Belger A, Carrión RE, Duncan E, Johannesen JK, Light GA, Niznikiewicz MA, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, Perkins DO, Tsuang MT, Walker EF, Woods SW, Cannon TD, Mathalon DH. PMID: 39552576.
      View in: PubMed   Mentions:    Fields:    
    2. Novel N100 area reliably captures aberrant sensory processing and is associated with neurocognition in early psychosis. Schizophr Res. 2024 Sep; 271:71-80. Machiraju SN, Wyss J, Light G, Braff DL, Cadenhead KS. PMID: 39013347.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. Sex moderates the effect of anhedonia on parietal alpha asymmetry. J Psychiatr Res. 2024 Sep; 177:97-101. Gupta RS, Light GA, Simmons AN, Harlé KM, Stout DM. PMID: 39002532.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Enhancing patient-clinician collaboration during treatment decision-making: study protocol for a community-engaged, mixed method hybrid type 1 trial of collaborative decision skills training (CDST) for veterans with psychosis. Trials. 2024 Jun 06; 25(1):363. Treichler EBH, McBride LE, Gomez E, Jain J, Seaton S, Yu KE, Oakes D, Perivoliotis D, Girard V, Reznik S, Salyers MP, Thomas ML, Spaulding WD, Granholm EL, Rabin BA, Light GA. PMID: 38840160; PMCID: PMC11155075.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    5. Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis. Schizophr Bull. 2024 Apr 30; 50(3):496-512. Wannan CMJ, Nelson B, Addington J, Allott K, Anticevic A, Arango C, Baker JT, Bearden CE, Billah T, Bouix S, Broome MR, Buccilli K, Cadenhead KS, Calkins ME, Cannon TD, Cecci G, Chen EYH, Cho KIK, Choi J, Clark SR, Coleman MJ, Conus P, Corcoran CM, Cornblatt BA, Diaz-Caneja CM, Dwyer D, Ebdrup BH, Ellman LM, Fusar-Poli P, Galindo L, Gaspar PA, Gerber C, Glenthøj LB, Glynn R, Harms MP, Horton LE, Kahn RS, Kambeitz J, Kambeitz-Ilankovic L, Kane JM, Kapur T, Keshavan MS, Kim SW, Koutsouleris N, Kubicki M, Kwon JS, Langbein K, Lewandowski KE, Light GA, Mamah D, Marcy PJ, Mathalon DH, McGorry PD, Mittal VA, Nordentoft M, Nunez A, Pasternak O, Pearlson GD, Perez J, Perkins DO, Powers AR, Roalf DR, Sabb FW, Schiffman J, Shah JL, Smesny S, Spark J, Stone WS, Strauss GP, Tamayo Z, Torous J, Upthegrove R, Vangel M, Verma S, Wang J, Rossum IW, Wolf DH, Wolff P, Wood SJ, Yung AR, Agurto C, Alvarez-Jimenez M, Amminger P, Armando M, Asgari-Targhi A, Cahill J, Carrión RE, Castro E, Cetin-Karayumak S, Mallar Chakravarty M, Cho YT, Cotter D, D'Alfonso S, Ennis M, Fadnavis S, Fonteneau C, Gao C, Gupta T, Gur RE, Gur RC, Hamilton HK, Hoftman GD, Jacobs GR, Jarcho J, Ji JL, Kohler CG, Lalousis PA, Lavoie S, Lepage M, Liebenthal E, Mervis J, Murty V, Nicholas SC, Ning L, Penzel N, Poldrack R, Polosecki P, Pratt DN, Rabin R, Rahimi Eichi H, Rathi Y, Reichenberg A, Reinen J, Rogers J, Ruiz-Yu B, Scott I, Seitz-Holland J, Srihari VH, Srivastava A, Thompson A, Turetsky BI, Walsh BC, Whitford T, Wigman JTW, Yao B, Yuen HP, Ahmed U, Byun AJS, Chung Y, Do K, Hendricks L, Huynh K, Jeffries C, Lane E, Langholm C, Lin E, Mantua V, Santorelli G, Ruparel K, Zoupou E, Adasme T, Addamo L, Adery L, Ali M, Auther A, Aversa S, Baek SH, Bates K, Bathery A, Bayer JMM, Beedham R, Bilgrami Z, Birch S, Bonoldi I, Borders O, Borgatti R, Brown L, Bruna A, Carrington H, Castillo-Passi RI, Chen J, Cheng N, Ching AE, Clifford C, Colton BL, Contreras P, Corral S, Damiani S, Done M, Estradé A, Etuka BA, Formica M, Furlan R, Geljic M, Germano C, Getachew R, Goncalves M, Haidar A, Hartmann J, Jo A, John O, Kerins S, Kerr M, Kesselring I, Kim H, Kim N, Kinney K, Krcmar M, Kotler E, Lafanechere M, Lee C, Llerena J, Markiewicz C, Matnejl P, Maturana A, Mavambu A, Mayol-Troncoso R, McDonnell A, McGowan A, McLaughlin D, McIlhenny R, McQueen B, Mebrahtu Y, Mensi M, Hui CLM, Suen YN, Wong SMY, Morrell N, Omar M, Partridge A, Phassouliotis C, Pichiecchio A, Politi P, Porter C, Provenzani U, Prunier N, Raj J, Ray S, Rayner V, Reyes M, Reynolds K, Rush S, Salinas C, Shetty J, Snowball C, Tod S, Turra-Fariña G, Valle D, Veale S, Whitson S, Wickham A, Youn S, Zamorano F, Zavaglia E, Zinberg J, Woods SW, Shenton ME. PMID: 38451304; PMCID: PMC11059785.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. Early auditory processing abnormalities alter individual learning trajectories and sensitivity to computerized cognitive training in schizophrenia. Psychol Med. 2024 Jul; 54(10):2669-2676. Molina JL, Joshi YB, Nungaray JA, Sprock J, Attarha M, Biagianti B, Thomas ML, Swerdlow NR, Light GA. PMID: 38587021.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    7. Predicting Conversion to Psychosis: What Lies Beyond the Biomarkers? Am J Psychiatry. 2024 Apr 01; 181(4):272-274. Light GA, Swerdlow NR. PMID: 38557145.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Clarifying directional dependence among measures of early auditory processing and cognition in schizophrenia: leveraging Gaussian graphical models and Bayesian networks. Psychol Med. 2024 Jul; 54(9):1930-1939. Abplanalp SJ, Braff DL, Light GA, Joshi YB, Nuechterlein KH, Green MF, Consortium on the Genetics of Schizophrenia. PMID: 38287656; PMCID: PMC11413352.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    9. Amphetamine increases motivation of humans and mice as measured by breakpoint, but does not affect an Electroencephalographic biomarker. Cogn Affect Behav Neurosci. 2024 Apr; 24(2):269-278. Noback M, Bhakta SG, Talledo JA, Kotz JE, Benster L, Roberts BZ, Nungaray JA, Light GA, Swerdlow NR, Brigman JL, Cavanagh JF, Young JW. PMID: 38168850; PMCID: PMC11060428.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    10. Points that Need Attention in Early Auditory Information Processing Research in Schizophrenia: Response to Lin and Hsieh. Am J Psychiatry. 2023 11 01; 180(11):841-842. Joshi Y, Swerdlow N, Light G. PMID: 37908092.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Click-train evoked steady state harmonic response as a novel pharmacodynamic biomarker of cortical oscillatory synchrony. Neuropharmacology. 2023 Dec 01; 240:109707. Gautam D, Raza MU, Miyakoshi M, Molina JL, Joshi YB, Clayson PE, Light GA, Swerdlow NR, Sivarao DV. PMID: 37673332.
      View in: PubMed   Mentions: 2     Fields:    
    12. Effects of Memantine on the Auditory Steady-State and Harmonic Responses to 40 Hz Stimulation Across Species. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Mar; 9(3):346-355. Swerdlow NR, Gonzalez CE, Raza MU, Gautam D, Miyakoshi M, Clayson PE, Joshi YB, Molina JL, Talledo J, Thomas ML, Light GA, Sivarao DV. PMID: 37683728.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    13. Mismatch negativity predicts initial auditory-based targeted cognitive training performance in a heterogeneous population across psychiatric disorders. Psychiatry Res. 2023 09; 327:115215. Joshi YB, Gonzalez CE, Molina JL, MacDonald LR, Min Din J, Minhas J, Leposke T, Nordberg B, Li F, Talledo J, Sprock J, Swerdlow NR, Light GA. PMID: 37406367.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    14. Sensitivity of Schizophrenia Endophenotype Biomarkers to Anticholinergic Medication Burden. Am J Psychiatry. 2023 07 01; 180(7):519-523. Joshi YB, Molina JL, Braff DL, Green MF, Gur RC, Gur RE, Nuechterlein KH, Stone WS, Greenwood TA, Lazzeroni LC, Radant AD, Silverman JM, Sprock J, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Swerdlow NR, Light GA. PMID: 37038743.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    15. Preliminary Evidence that Memantine Enhances Prepulse Effects on Startle Magnitude and Latency in Patients with Alzheimer's Disease. J Alzheimers Dis. 2023; 91(1):355-362. Swerdlow NR, Joshi YB, Sprock J, Talledo J, Molina JL, Delano-Wood L, Iwanaga D, Kotz JE, Huege S, Léger GC, Light GA. PMID: 36404550.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    16. Using a stakeholder-engaged, iterative, and systematic approach to adapting collaborative decision skills training for implementation in VA psychosocial rehabilitation and recovery centers. BMC Health Serv Res. 2022 Dec 17; 22(1):1543. Treichler EBH, Mercado R, Oakes D, Perivoliotis D, Gallegos-Rodriguez Y, Sosa E, Cisneros E, Spaulding WD, Granholm E, Light GA, Rabin B. PMID: 36528579; PMCID: PMC9759039.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    17. Understanding Connections and Boundaries Between Positive Symptoms, Negative Symptoms, and Role Functioning Among Individuals With Schizophrenia: A Network Psychometric Approach. JAMA Psychiatry. 2022 10 01; 79(10):1014-1022. Abplanalp SJ, Braff DL, Light GA, Nuechterlein KH, Green MF, Consortium on the Genetics of Schizophrenia-2. PMID: 35976655; PMCID: PMC9386606.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    18. Auditory N100 amplitude deficits predict conversion to psychosis in the North American Prodrome Longitudinal Study (NAPLS-2) cohort. Schizophr Res. 2022 10; 248:89-97. Duncan E, Roach BJ, Massa N, Hamilton HK, Bachman PM, Belger A, Carrion RE, Johannesen JK, Light GA, Niznikiewicz MA, Addington JM, Bearden CE, Cadenhead KS, Cannon TD, Cornblatt BA, McGlashan TH, Perkins DO, Tsuang M, Walker EF, Woods SW, Nasiri N, Mathalon DH. PMID: 35994912; PMCID: PMC10091223.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    19. Mismatch Negativity in Response to Auditory Deviance and Risk for Future Psychosis in Youth at Clinical High Risk for Psychosis. JAMA Psychiatry. 2022 08 01; 79(8):780-789. Hamilton HK, Roach BJ, Bachman PM, Belger A, Carrión RE, Duncan E, Johannesen JK, Light GA, Niznikiewicz MA, Addington J, Bearden CE, Cadenhead KS, Cornblatt BA, McGlashan TH, Perkins DO, Tsuang MT, Walker EF, Woods SW, Cannon TD, Mathalon DH. PMID: 35675082; PMCID: PMC9178501.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    20. Correction to: Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms. Transl Psychiatry. 2022 Jul 21; 12(1):290. Cavanagh JF, Gregg D, Light GA, Olguin SL, Sharp RF, Bismark AW, Bhakta SG, Swerdlow NR, Brigman JL, Young JW. PMID: 35864090; PMCID: PMC9304120.
      View in: PubMed   Mentions:    Fields:    
    21. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. 2022 04; 604(7906):502-508. Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, Gopal S, Gratten J, Green MF, Greenwood TA, Guillin O, Gülöksüz S, Gur RE, Gur RC, Gutiérrez B, Hahn E, Hakonarson H, Haroutunian V, Hartmann AM, Harvey C, Hayward C, Henskens FA, Herms S, Hoffmann P, Howrigan DP, Ikeda M, Iyegbe C, Joa I, Julià A, Kähler AK, Kam-Thong T, Kamatani Y, Karachanak-Yankova S, Kebir O, Keller MC, Kelly BJ, Khrunin A, Kim SW, Klovins J, Kondratiev N, Konte B, Kraft J, Kubo M, Kucinskas V, Kucinskiene ZA, Kusumawardhani A, Kuzelova-Ptackova H, Landi S, Lazzeroni LC, Lee PH, Legge SE, Lehrer DS, Lencer R, Lerer B, Li M, Lieberman J, Light GA, Limborska S, Liu CM, Lönnqvist J, Loughland CM, Lubinski J, Luykx JJ, Lynham A, Macek M, Mackinnon A, Magnusson PKE, Maher BS, Maier W, Malaspina D, Mallet J, Marder SR, Marsal S, Martin AR, Martorell L, Mattheisen M, McCarley RW, McDonald C, McGrath JJ, Medeiros H, Meier S, Melegh B, Melle I, Mesholam-Gately RI, Metspalu A, Michie PT, Milani L, Milanova V, Mitjans M, Molden E, Molina E, Molto MD, Mondelli V, Moreno C, Morley CP, Muntané G, Murphy KC, Myin-Germeys I, Nenadic I, Nestadt G, Nikitina-Zake L, Noto C, Nuechterlein KH, O'Brien NL, O'Neill FA, Oh SY, Olincy A, Ota VK, Pantelis C, Papadimitriou GN, Parellada M, Paunio T, Pellegrino R, Periyasamy S, Perkins DO, Pfuhlmann B, Pietiläinen O, Pimm J, Porteous D, Powell J, Quattrone D, Quested D, Radant AD, Rampino A, Rapaport MH, Rautanen A, Reichenberg A, Roe C, Roffman JL, Roth J, Rothermundt M, Rutten BPF, Saker-Delye S, Salomaa V, Sanjuan J, Santoro ML, Savitz A, Schall U, Scott RJ, Seidman LJ, Sharp SI, Shi J, Siever LJ, Sigurdsson E, Sim K, Skarabis N, Slominsky P, So HC, Sobell JL, Söderman E, Stain HJ, Steen NE, Steixner-Kumar AA, Stögmann E, Stone WS, Straub RE, Streit F, Strengman E, Stroup TS, Subramaniam M, Sugar CA, Suvisaari J, Svrakic DM, Swerdlow NR, Szatkiewicz JP, Ta TMT, Takahashi A, Terao C, Thibaut F, Toncheva D, Tooney PA, Torretta S, Tosato S, Tura GB, Turetsky BI, Üçok A, Vaaler A, van Amelsvoort T, van Winkel R, Veijola J, Waddington J, Walter H, Waterreus A, Webb BT, Weiser M, Williams NM, Witt SH, Wormley BK, Wu JQ, Xu Z, Yolken R, Zai CC, Zhou W, Zhu F, Zimprich F, Atbasoglu EC, Ayub M, Benner C, Bertolino A, Black DW, Bray NJ, Breen G, Buccola NG, Byerley WF, Chen WJ, Cloninger CR, Crespo-Facorro B, et al. PMID: 35396580; PMCID: PMC9392466.
      View in: PubMed   Mentions: 736     Fields:    Translation:Humans
    22. A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M1 receptor agonist HTL0018318 in patients with mild-to-moderate Alzheimer's disease. Alzheimers Dement (N Y). 2022; 8(1):e12273. Nathan PJ, Millais SB, Godwood A, Dewit O, Cross DM, Liptrot J, Ruparelia B, Jones SP, Bakker G, Maruff PT, Light GA, Brown AJH, Weir MP, Congreve M, Tasker T. PMID: 35229025; PMCID: PMC8864442.
      View in: PubMed   Mentions: 4  
    23. High-power gamma-related delta phase alteration in schizophrenia patients at rest. Psychiatry Clin Neurosci. 2022 May; 76(5):179-186. Koshiyama D, Miyakoshi M, Tanaka-Koshiyama K, Sprock J, Light GA. PMID: 35037330.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    24. Amphetamine alters an EEG marker of reward processing in humans and mice. Psychopharmacology (Berl). 2022 Mar; 239(3):923-933. Cavanagh JF, Olguin SL, Talledo JA, Kotz JE, Roberts BZ, Nungaray JA, Sprock J, Gregg D, Bhakta SG, Light GA, Swerdlow NR, Young JW, Brigman JL. PMID: 35132440; PMCID: PMC8891070.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    25. EEG reveals that dextroamphetamine improves cognitive control through multiple processes in healthy participants. Neuropsychopharmacology. 2022 04; 47(5):1029-1036. Bhakta SG, Cavanagh JF, Talledo JA, Kotz JE, Benster L, Roberts BZ, Nungaray JA, Brigman JL, Light GA, Swerdlow NR, Young JW. PMID: 35042948; PMCID: PMC8938448.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    26. Evaluation of the frequency following response as a predictive biomarker of response to cognitive training in schizophrenia. Psychiatry Res. 2021 11; 305:114239. Clayson PE, Molina JL, Joshi YB, Thomas ML, Sprock J, Nungaray J, Swerdlow NR, Light GA. PMID: 34673326.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    27. Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms. Transl Psychiatry. 2021 09 17; 11(1):482. Cavanagh JF, Gregg D, Light GA, Olguin SL, Sharp RF, Bismark AW, Bhakta SG, Swerdlow NR, Brigman JL, Young JW. PMID: 34535625; PMCID: PMC8448772.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    28. Central auditory processing deficits in schizophrenia: Effects of auditory-based cognitive training. Schizophr Res. 2021 10; 236:135-141. Molina JL, Joshi YB, Nungaray JA, Thomas ML, Sprock J, Clayson PE, Sanchez VA, Attarha M, Biagianti B, Swerdlow NR, Light GA. PMID: 34500174; PMCID: PMC9259506.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    29. How Shared Is Shared Decision Making? Reaching the Full Potential of Patient-Clinician Collaboration in Mental Health. Harv Rev Psychiatry. 2021 Sep-Oct 01; 29(5):361-369. Treichler EBH, Rabin BA, Cohen AN, Light GA. PMID: 34352846.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    30. The viability of the frequency following response characteristics for use as biomarkers of cognitive therapeutics in schizophrenia. Schizophr Res. 2022 05; 243:372-382. Clayson PE, Joshi YB, Thomas ML, Tarasenko M, Bismark A, Sprock J, Nungaray J, Cardoso L, Wynn JK, Swerdlow NR, Light GA. PMID: 34187732.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Anticholinergic Medication Burden-Associated Cognitive Impairment in Schizophrenia. Am J Psychiatry. 2021 09 01; 178(9):838-847. Joshi YB, Thomas ML, Braff DL, Green MF, Gur RC, Gur RE, Nuechterlein KH, Stone WS, Greenwood TA, Lazzeroni LC, MacDonald LR, Molina JL, Nungaray JA, Radant AD, Silverman JM, Sprock J, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Swerdlow NR, Light GA. PMID: 33985348; PMCID: PMC8440496.
      View in: PubMed   Mentions: 47     Fields:    Translation:Humans
    32. Detecting the Inverted-U in fMRI Studies of Schizophrenia: A Comparison of Three Analysis Methods. J Int Neuropsychol Soc. 2022 03; 28(3):258-269. Thomas ML, Duffy JR, Swerdlow N, Light GA, Brown GG. PMID: 33949299; PMCID: PMC8568731.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    33. Auditory discrimination and frequency modulation learning in schizophrenia patients: amphetamine within-subject dose response and time course. Psychol Med. 2023 01; 53(1):140-148. Swerdlow NR, Bhakta SG, Talledo J, Benster L, Kotz J, Vinogradov S, Molina JL, Light GA. PMID: 33849683; PMCID: PMC8514598.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    34. Skills-based intervention to enhance collaborative decision-making: systematic adaptation and open trial protocol for veterans with psychosis. Pilot Feasibility Stud. 2021 Mar 29; 7(1):89. Treichler EBH, Rabin BA, Spaulding WD, Thomas ML, Salyers MP, Granholm EL, Cohen AN, Light GA. PMID: 33781352; PMCID: PMC8005669.
      View in: PubMed   Mentions: 5  
    35. Abnormal phase discontinuity of alpha- and theta-frequency oscillations in schizophrenia. Schizophr Res. 2021 05; 231:73-81. Koshiyama D, Miyakoshi M, Tanaka-Koshiyama K, Joshi YB, Sprock J, Braff DL, Light GA. PMID: 33780847; PMCID: PMC8222093.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
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    97. Gating Deficit Heritability and Correlation With Increased Clinical Severity in Schizophrenia Patients With Positive Family History. Am J Psychiatry. 2016 Apr 01; 173(4):385-91. Greenwood TA, Light GA, Swerdlow NR, Calkins ME, Green MF, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Freedman R, Braff DL. PMID: 26441157; PMCID: PMC4933520.
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    98. Memantine Effects On Sensorimotor Gating and Mismatch Negativity in Patients with Chronic Psychosis. Neuropsychopharmacology. 2016 Jan; 41(2):419-30. Swerdlow NR, Bhakta S, Chou HH, Talledo JA, Balvaneda B, Light GA. PMID: 26062785; PMCID: PMC5130118.
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    99. Bending the curve on psychosis outcomes. Lancet Psychiatry. 2015 May; 2(5):365-367. Light GA, Swerdlow NR. PMID: 26360262; PMCID: PMC5072396.
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    100. GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders. Neuropsychopharmacology. 2015 Nov; 40(12):2715-26. Young JW, Kamenski ME, Higa KK, Light GA, Geyer MA, Zhou X. PMID: 25907107; PMCID: PMC4864647.
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    101. Neurocognitive performance in family-based and case-control studies of schizophrenia. Schizophr Res. 2015 Apr; 163(1-3):17-23. Gur RC, Braff DL, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Lazzeroni LC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar CA, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Gur RE. PMID: 25432636; PMCID: PMC4441547.
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    102. Future clinical uses of neurophysiological biomarkers to predict and monitor treatment response for schizophrenia. Ann N Y Acad Sci. 2015 May; 1344:105-19. Light GA, Swerdlow NR. PMID: 25752648; PMCID: PMC4412775.
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    103. Attention/vigilance in schizophrenia: performance results from a large multi-site study of the Consortium on the Genetics of Schizophrenia (COGS). Schizophr Res. 2015 Apr; 163(1-3):38-46. Nuechterlein KH, Green MF, Calkins ME, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar CA, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 25749017; PMCID: PMC4382444.
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    104. Factor structure and heritability of endophenotypes in schizophrenia: findings from the Consortium on the Genetics of Schizophrenia (COGS-1). Schizophr Res. 2015 Apr; 163(1-3):73-9. Seidman LJ, Hellemann G, Nuechterlein KH, Greenwood TA, Braff DL, Cadenhead KS, Calkins ME, Freedman R, Gur RE, Gur RC, Lazzeroni LC, Light GA, Olincy A, Radant AD, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar C, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Green MF. PMID: 25682549; PMCID: PMC5944296.
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    105. Electroencephalographic biomarkers of psychosis: present and future. Biol Psychiatry. 2015 Jan 15; 77(2):87-9. Light GA, Makeig S. PMID: 25524305.
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    106. Robust differences in antisaccade performance exist between COGS schizophrenia cases and controls regardless of recruitment strategies. Schizophr Res. 2015 Apr; 163(1-3):47-52. Radant AD, Millard SP, Braff DL, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Meichle SP, Nuechterlein KH, Olincy A, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Sugar CA, Tsuang MT, Turetsky BI, Tsuang DW. PMID: 25553977; PMCID: PMC4382408.
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    107. California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS). Schizophr Res. 2015 Apr; 163(1-3):32-7. Stone WS, Mesholam-Gately RI, Braff DL, Calkins ME, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Siever LJ, Silverman JM, Sprock J, Sugar CA, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Seidman LJ. PMID: 25497440; PMCID: PMC5954831.
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    108. Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: characterization of demographic, clinical, cognitive, and functional correlates in COGS-2. Schizophr Res. 2015 Apr; 163(1-3):63-72. Light GA, Swerdlow NR, Thomas ML, Calkins ME, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Pela M, Radant AD, Seidman LJ, Sharp RF, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Braff DL, Turetsky BI. PMID: 25449710; PMCID: PMC4382452.
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    109. The auditory brain-stem response to complex sounds: a potential biomarker for guiding treatment of psychosis. Front Psychiatry. 2014; 5:142. Tarasenko MA, Swerdlow NR, Makeig S, Braff DL, Light GA. PMID: 25352811; PMCID: PMC4195270.
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    110. The utility of P300 as a schizophrenia endophenotype and predictive biomarker: clinical and socio-demographic modulators in COGS-2. Schizophr Res. 2015 Apr; 163(1-3):53-62. Turetsky BI, Dress EM, Braff DL, Calkins ME, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar CA, Swerdlow NR, Tsuang DW, Tsuang MT, Light G. PMID: 25306203; PMCID: PMC4382423.
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    111. Cortical substrates and functional correlates of auditory deviance processing deficits in schizophrenia. Neuroimage Clin. 2014; 6:424-37. Rissling AJ, Miyakoshi M, Sugar CA, Braff DL, Makeig S, Light GA. PMID: 25379456; PMCID: PMC4218942.
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    112. Verbal working memory in schizophrenia from the Consortium on the Genetics of Schizophrenia (COGS) study: the moderating role of smoking status and antipsychotic medications. Schizophr Res. 2015 Apr; 163(1-3):24-31. Lee J, Green MF, Calkins ME, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Nuechterlein KH, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar CA, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 25248939; PMCID: PMC4368500.
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    113. Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. Schizophr Bull. 2014 Nov; 40(6):1404-11. Light G, Greenwood TA, Swerdlow NR, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Sprock J, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 24903414; PMCID: PMC4193725.
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    114. Paternal age of schizophrenia probands and endophenotypic differences from unaffected siblings. Psychiatry Res. 2014 Sep 30; 219(1):67-71. Schmeidler J, Lazzeroni LC, Swerdlow NR, Ferreira RP, Braff DL, Calkins ME, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Olincy A, Nuechterlein KH, Radant AD, Seidman LJ, Siever LJ, Stone WS, Sprock J, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Silverman JM. PMID: 24913833; PMCID: PMC4110721.
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    115. Not all distraction is bad: working memory vulnerability to implicit socioemotional distraction correlates with negative symptoms and functional impairment in psychosis. Schizophr Res Treatment. 2014; 2014:320948. Mano QR, Brown GG, Mirzakhanian H, Bolden K, Cadenhead KS, Light GA. PMID: 24724026; PMCID: PMC3958678.
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    116. Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia? PLoS One. 2014; 9(2):e88379. Tsuang D, Esterberg M, Braff D, Calkins M, Cadenhead K, Dobie D, Freedman R, Green MF, Greenwood T, Gur R, Gur R, Horan W, Lazzeroni LC, Light GA, Millard SP, Olincy A, Nuechterlein K, Seidman L, Siever L, Silverman J, Stone W, Sprock J, Sugar C, Swerdlow N, Tsuang M, Turetsky B, Radant A. PMID: 24523888; PMCID: PMC3921166.
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    117. Deficient prepulse inhibition in schizophrenia detected by the multi-site COGS. Schizophr Res. 2014 Feb; 152(2-3):503-12. Swerdlow NR, Light GA, Sprock J, Calkins ME, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Radant AD, Ray A, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 24405980; PMCID: PMC3960985.
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    118. Using biomarkers to inform diagnosis, guide treatments and track response to interventions in psychotic illnesses. Biomark Med. 2014; 8(1):9-14. Perez VB, Swerdlow NR, Braff DL, Näätänen R, Light GA. PMID: 24325220; PMCID: PMC4043396.
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    119. Neurophysiological biomarkers informing the clinical neuroscience of schizophrenia: mismatch negativity and prepulse inhibition of startle. Curr Top Behav Neurosci. 2014; 21:293-314. Light GA, Swerdlow NR. PMID: 24850080; PMCID: PMC5951188.
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    120. Reverse translation of the rodent 5C-CPT reveals that the impaired attention of people with schizophrenia is similar to scopolamine-induced deficits in mice. Transl Psychiatry. 2013 Nov 12; 3:e324. Young JW, Geyer MA, Rissling AJ, Sharp RF, Eyler LT, Asgaard GL, Light GA. PMID: 24217494; PMCID: PMC3849961.
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    121. Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats. Behav Brain Res. 2013 Nov 15; 257:118-28. Swerdlow NR, Light GA, Trim RS, Breier MR, Hines SR, Powell SB. PMID: 24076151; PMCID: PMC3897308.
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    122. Mismatch negativity is a breakthrough biomarker for understanding and treating psychotic disorders. Proc Natl Acad Sci U S A. 2013 Sep 17; 110(38):15175-6. Light GA, Näätänen R. PMID: 23995447; PMCID: PMC3780842.
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    123. Between-site reliability of startle prepulse inhibition across two early psychosis consortia. Neuroreport. 2013 Aug 07; 24(11):626-30. Cadenhead KS, Addington J, Cannon TD, Cornblatt BA, de la Fuente-Sandoval C, Mathalon DH, Perkins DO, Seidman LJ, Tsuang M, Walker EF, Woods SW, Bachman P, Belger A, Carrión RE, Donkers FC, Duncan E, Johannesen J, León-Ortiz P, Light G, Mondragón A, Niznikiewicz M, Nunag J, Roach BJ, Solís-Vivanco R, North American Prodromal Longitudinal Studies Consortium. PMID: 23799460; PMCID: PMC4135529.
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    124. Coupling of gene expression in medial prefrontal cortex and nucleus accumbens after neonatal ventral hippocampal lesions accompanies deficits in sensorimotor gating and auditory processing in rats. Neuropharmacology. 2013 Dec; 75:38-46. Swerdlow NR, Powell SB, Breier MR, Hines SR, Light GA. PMID: 23810830; PMCID: PMC3825835.
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    125. Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2013 May; 170(5):521-32. Greenwood TA, Swerdlow NR, Gur RE, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Ray A, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Light GA, Braff DL. PMID: 23511790; PMCID: PMC3878873.
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    126. Demand and modality of directed attention modulate "pre-attentive" sensory processes in schizophrenia patients and nonpsychiatric controls. Schizophr Res. 2013 May; 146(1-3):326-35. Rissling AJ, Park SH, Young JW, Rissling MB, Sugar CA, Sprock J, Mathias DJ, Pela M, Sharp RF, Braff DL, Light GA. PMID: 23490760; PMCID: PMC3622836.
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    127. Sex differences in familiality effects on neurocognitive performance in schizophrenia. Biol Psychiatry. 2013 May 15; 73(10):976-84. Calkins ME, Ray A, Gur RC, Freedman R, Green MF, Greenwood TA, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar C, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL, Lazzeroni LC, Gur RE. PMID: 23395246; PMCID: PMC3954126.
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    128. Neural substrates of normal and impaired preattentive sensory discrimination in large cohorts of nonpsychiatric subjects and schizophrenia patients as indexed by MMN and P3a change detection responses. Neuroimage. 2013 Feb 01; 66:594-603. Takahashi H, Rissling AJ, Pascual-Marqui R, Kirihara K, Pela M, Sprock J, Braff DL, Light GA. PMID: 23085112; PMCID: PMC3652903.
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    129. Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia. PLoS One. 2012; 7(7):e39434. Light GA, Swerdlow NR, Rissling AJ, Radant A, Sugar CA, Sprock J, Pela M, Geyer MA, Braff DL. PMID: 22802938; PMCID: PMC3389010.
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    130. Fronto-temporal-mesolimbic gene expression and heritable differences in amphetamine-disrupted sensorimotor gating in rats. Psychopharmacology (Berl). 2012 Dec; 224(3):349-62. Swerdlow NR, Shilling PD, Breier M, Trim RS, Light GA, Marie RS. PMID: 22700037; PMCID: PMC5215002.
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    131. Disentangling early sensory information processing deficits in schizophrenia. Clin Neurophysiol. 2012 Oct; 123(10):1942-9. Rissling AJ, Braff DL, Swerdlow NR, Hellemann G, Rassovsky Y, Sprock J, Pela M, Light GA. PMID: 22608970; PMCID: PMC3436955.
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    132. Sensory and sensorimotor gating deficits after neonatal ventral hippocampal lesions in rats. Dev Neurosci. 2012; 34(2-3):240-9. Swerdlow NR, Light GA, Breier MR, Shoemaker JM, Saint Marie RL, Neary AC, Geyer MA, Stevens KE, Powell SB. PMID: 22572564.
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    133. Older patients with schizophrenia: does military veteran status matter? Am J Geriatr Psychiatry. 2012 Mar; 20(3):248-56. Thorp SR, Sones HM, Glorioso D, Thompson W, Light GA, Golshan S, Jeste DV. PMID: 22354115; PMCID: PMC3286234.
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    134. Hierarchical organization of gamma and theta oscillatory dynamics in schizophrenia. Biol Psychiatry. 2012 May 15; 71(10):873-80. Kirihara K, Rissling AJ, Swerdlow NR, Braff DL, Light GA. PMID: 22361076; PMCID: PMC3434875.
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    135. Association analysis of 94 candidate genes and schizophrenia-related endophenotypes. PLoS One. 2012; 7(1):e29630. Greenwood TA, Light GA, Swerdlow NR, Radant AD, Braff DL. PMID: 22253750; PMCID: PMC3258248.
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    136. γ oscillations in schizophrenia: mechanisms and clinical significance. Brain Res. 2011 Sep 21; 1413:98-114. Sun Y, Farzan F, Barr MS, Kirihara K, Fitzgerald PB, Light GA, Daskalakis ZJ. PMID: 21840506.
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    137. Automatic sensory information processing abnormalities across the illness course of schizophrenia. Psychol Med. 2012 Jan; 42(1):85-97. Jahshan C, Cadenhead KS, Rissling AJ, Kirihara K, Braff DL, Light GA. PMID: 21740622; PMCID: PMC3193558.
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    138. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. Am J Psychiatry. 2011 Sep; 168(9):930-46. Greenwood TA, Lazzeroni LC, Murray SS, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Gur RE, Gur RC, Hardiman G, Kelsoe JR, Leonard S, Light GA, Nuechterlein KH, Olincy A, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Freedman R, Braff DL. PMID: 21498463; PMCID: PMC3751972.
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    139. Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS). Schizophr Res. 2011 May; 128(1-3):102-10. Stone WS, Giuliano AJ, Tsuang MT, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Faraone SV, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Roe AH, Schork NJ, Siever LJ, Silverman JM, Swerdlow NR, Thomas AR, Tsuang DW, Turetsky BI, Seidman LJ. PMID: 21288694; PMCID: PMC6819951.
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    140. Neurophysiologic markers of abnormal brain activity in schizophrenia. Curr Psychiatry Rep. 2010 Dec; 12(6):572-8. Rissling AJ, Makeig S, Braff DL, Light GA. PMID: 20857348; PMCID: PMC2965365.
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    141. Superior size-weight illusion performance in patients with schizophrenia: evidence for deficits in forward models. Schizophr Res. 2010 Aug; 121(1-3):101-6. Williams LE, Ramachandran VS, Hubbard EM, Braff DL, Light GA. PMID: 19931421; PMCID: PMC2910228.
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    142. Electroencephalography (EEG) and event-related potentials (ERPs) with human participants. Curr Protoc Neurosci. 2010 Jul; Chapter 6:Unit 6.25.1-24. Light GA, Williams LE, Minow F, Sprock J, Rissling A, Sharp R, Swerdlow NR, Braff DL. PMID: 20578033; PMCID: PMC2909037.
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    143. Reduced multisensory integration in patients with schizophrenia on a target detection task. Neuropsychologia. 2010 Aug; 48(10):3128-36. Williams LE, Light GA, Braff DL, Ramachandran VS. PMID: 20600181; PMCID: PMC2915827.
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    144. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophr Res. 2010 Jun; 119(1-3):175-82. Olincy A, Braff DL, Adler LE, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Wagner BD, Freedman R. PMID: 20382002; PMCID: PMC3688282.
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    145. Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology. 2010 Sep; 47(5):846-56. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Meichle SP, Millard SP, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. PMID: 20374545; PMCID: PMC4176871.
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    146. Sensory and sensorimotor gating-disruptive effects of apomorphine in Sprague Dawley and Long Evans rats. Behav Brain Res. 2010 Apr 02; 208(2):560-5. Breier MR, Lewis B, Shoemaker JM, Light GA, Swerdlow NR. PMID: 20080128; PMCID: PMC2834557.
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    147. Neurophysiological measures of sensory registration, stimulus discrimination, and selection in schizophrenia patients. Curr Top Behav Neurosci. 2010; 4:283-309. Rissling AJ, Light GA. PMID: 21312404.
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    148. The relationship between preattentive sensory processing deficits and age in schizophrenia patients. Clin Neurophysiol. 2009 Nov; 120(11):1949-1957. Kiang M, Braff DL, Sprock J, Light GA. PMID: 19786365; PMCID: PMC2902236.
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    149. The 5-choice continuous performance test: evidence for a translational test of vigilance for mice. PLoS One. 2009; 4(1):e4227. Young JW, Light GA, Marston HM, Sharp R, Geyer MA. PMID: 19156216; PMCID: PMC2626630.
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    150. Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands. Biol Psychiatry. 2008 Dec 15; 64(12):1051-9. Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Calkins ME. PMID: 18701089; PMCID: PMC2653714.
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    151. Realistic expectations of prepulse inhibition in translational models for schizophrenia research. Psychopharmacology (Berl). 2008 Aug; 199(3):331-88. Swerdlow NR, Weber M, Qu Y, Light GA, Braff DL. PMID: 18568339; PMCID: PMC2771731.
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    152. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2008 Aug; 103(1-3):218-28. Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Olincy A, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Green MF. PMID: 18406578; PMCID: PMC2529172.
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    153. Advances in endophenotyping schizophrenia. World Psychiatry. 2008 Feb; 7(1):11-8. Braff DL, Greenwood TA, Swerdlow NR, Light GA, Schork NJ, Investigators of the Consortium on the Genetics of Schizophrenia. PMID: 18458787; PMCID: PMC2359727.
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    154. An event-related brain potential study of direct and indirect semantic priming in schizophrenia. Am J Psychiatry. 2008 Jan; 165(1):74-81. Kiang M, Kutas M, Light GA, Braff DL. PMID: 18056222.
      View in: PubMed   Mentions: 32     Fields:    Translation:Humans
    155. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Arch Gen Psychiatry. 2007 Nov; 64(11):1242-50. Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Schork NJ. PMID: 17984393; PMCID: PMC10588564.
      View in: PubMed   Mentions: 188     Fields:    Translation:Humans
    156. Preattentive sensory processing as indexed by the MMN and P3a brain responses is associated with cognitive and psychosocial functioning in healthy adults. J Cogn Neurosci. 2007 Oct; 19(10):1624-32. Light GA, Swerdlow NR, Braff DL. PMID: 18271737; PMCID: PMC2562660.
      View in: PubMed   Mentions: 76     Fields:    Translation:Humans
    157. Relationship between P50 suppression and the cortical silent period. Neuroreport. 2007 Sep 17; 18(14):1503-6. Möller B, Light GA, Fitzgerald PB, Snyder JS, Chen R, Daskalakis ZJ. PMID: 17712283.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    158. Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: a double-blind, randomized controlled trial. Schizophr Res. 2007 Sep; 95(1-3):134-42. Wynn JK, Green MF, Sprock J, Light GA, Widmark C, Reist C, Erhart S, Marder SR, Mintz J, Braff DL. PMID: 17662577; PMCID: PMC2716219.
      View in: PubMed   Mentions: 28     Fields:    Translation:Humans
    159. Cognitive, neurophysiological, and functional correlates of proverb interpretation abnormalities in schizophrenia. J Int Neuropsychol Soc. 2007 Jul; 13(4):653-63. Kiang M, Light GA, Prugh J, Coulson S, Braff DL, Kutas M. PMID: 17521483.
      View in: PubMed   Mentions: 40     Fields:    Translation:Humans
    160. Electrophysiological insights into conceptual disorganization in schizophrenia. Schizophr Res. 2007 May; 92(1-3):225-36. Kiang M, Kutas M, Light GA, Braff DL. PMID: 17383161; PMCID: PMC3974604.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    161. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophr Res. 2007 May; 92(1-3):237-51. Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 17346930; PMCID: PMC2039885.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    162. Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients. Biol Psychiatry. 2007 May 15; 61(10):1204-7. Braff DL, Light GA, Swerdlow NR. PMID: 17161386.
      View in: PubMed   Mentions: 41     Fields:    Translation:Humans
    163. Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function. Arch Gen Psychiatry. 2006 Dec; 63(12):1325-35. Swerdlow NR, Light GA, Cadenhead KS, Sprock J, Hsieh MH, Braff DL. PMID: 17146007.
      View in: PubMed   Mentions: 156     Fields:    Translation:Humans
    164. Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures. Schizophr Bull. 2007 Jan; 33(1):69-94. Turetsky BI, Calkins ME, Light GA, Olincy A, Radant AD, Swerdlow NR. PMID: 17135482; PMCID: PMC2632291.
      View in: PubMed   Mentions: 218     Fields:    Translation:Humans
    165. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophr Bull. 2007 Jan; 33(1):33-48. Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang DW, Tsuang MT, Turetsky BI, Braff DL. PMID: 17035358; PMCID: PMC2632302.
      View in: PubMed   Mentions: 80     Fields:    Translation:Humans
    166. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophr Res. 2007 Jan; 89(1-3):320-9. Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork NJ, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Swerdlow NR, Tsuang MT, Turetsky BI, Tsuang DW. PMID: 17023145.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    167. Gamma band oscillations reveal neural network cortical coherence dysfunction in schizophrenia patients. Biol Psychiatry. 2006 Dec 01; 60(11):1231-40. Light GA, Hsu JL, Hsieh MH, Meyer-Gomes K, Sprock J, Swerdlow NR, Braff DL. PMID: 16893524.
      View in: PubMed   Mentions: 198     Fields:    Translation:Humans
    168. Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats. Neuropsychopharmacology. 2006 Mar; 31(3):506-15. Swerdlow NR, Geyer MA, Shoemaker JM, Light GA, Braff DL, Stevens KE, Sharp R, Breier M, Neary A, Auerbach PP. PMID: 16123772; PMCID: PMC1373667.
      View in: PubMed   Mentions: 18     Fields:    Translation:Animals
    169. Event-related gamma activity in schizophrenia patients during a visual backward-masking task. Am J Psychiatry. 2005 Dec; 162(12):2330-6. Wynn JK, Light GA, Breitmeyer B, Nuechterlein KH, Green MF. PMID: 16330598; PMCID: PMC9973373.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    170. Stability of mismatch negativity deficits and their relationship to functional impairments in chronic schizophrenia. Am J Psychiatry. 2005 Sep; 162(9):1741-3. Light GA, Braff DL. PMID: 16135637.
      View in: PubMed   Mentions: 82     Fields:    Translation:Humans
    171. Efficacy and tolerability of low-dose donepezil in schizophrenia. Clin Neuropharmacol. 2005 Jul-Aug; 28(4):179-84. Erickson SK, Schwarzkopf SB, Palumbo D, Badgley-Fleeman J, Smirnow AM, Light GA. PMID: 16062097.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    172. P50 suppression in individuals at risk for schizophrenia: the convergence of clinical, familial, and vulnerability marker risk assessment. Biol Psychiatry. 2005 Jun 15; 57(12):1504-9. Cadenhead KS, Light GA, Shafer KM, Braff DL. PMID: 15953486.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    173. On the waveform of the acoustic startle blink in the paradigm of prepulse inhibition - methodological and physiological aspects. Neuropsychobiology. 2005; 52(1):24-7. Meincke U, Light GA, Geyer MA, Braff DL. PMID: 15942260.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    174. Prepulse inhibition of perceived stimulus intensity: paradigm assessment. Biol Psychol. 2005 May; 69(2):133-47. Swerdlow NR, Stephany NL, Talledo J, Light G, Braff DL, Baeyens D, Auerbach PP. PMID: 15804542.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    175. Female schizophrenia patients have prepulse inhibition deficits. Biol Psychiatry. 2005 Apr 01; 57(7):817-20. Braff DL, Light GA, Ellwanger J, Sprock J, Swerdlow NR. PMID: 15820241.
      View in: PubMed   Mentions: 30     Fields:    Translation:Humans
    176. Mismatch negativity deficits are associated with poor functioning in schizophrenia patients. Arch Gen Psychiatry. 2005 Feb; 62(2):127-36. Light GA, Braff DL. PMID: 15699289.
      View in: PubMed   Mentions: 171     Fields:    Translation:Humans
    177. The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia. Dialogues Clin Neurosci. 2005; 7(2):125-35. Braff DL, Light GA. PMID: 16262208; PMCID: PMC3181726.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimals
    178. Preattentional and attentional cognitive deficits as targets for treating schizophrenia. Psychopharmacology (Berl). 2004 Jun; 174(1):75-85. Braff DL, Light GA. PMID: 15118804.
      View in: PubMed   Mentions: 78     Fields:    Translation:HumansAnimals
    179. Sensitization and habituation of the acoustic startle reflex in patients with schizophrenia. Psychiatry Res. 2004 Apr 15; 126(1):51-61. Meincke U, Light GA, Geyer MA, Braff DL, Gouzoulis-Mayfrank E. PMID: 15081627.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    180. Visual masking as a probe for abnormal gamma range activity in schizophrenia. Biol Psychiatry. 2003 Jun 15; 53(12):1113-9. Green MF, Mintz J, Salveson D, Nuechterlein KH, Breitmeyer B, Light GA, Braff DL. PMID: 12814862.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    181. Neurobiological measures of schizotypal personality disorder: defining an inhibitory endophenotype? Am J Psychiatry. 2002 May; 159(5):869-71. Cadenhead KS, Light GA, Geyer MA, McDowell JE, Braff DL. PMID: 11986147.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    182. Measuring P50 suppression and prepulse inhibition in a single recording session. Am J Psychiatry. 2001 Dec; 158(12):2066-8. Light GA, Braff DL. PMID: 11729028.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    183. Impact of prepulse characteristics on the detection of sensorimotor gating deficits in schizophrenia. Schizophr Res. 2001 Apr 15; 49(1-2):171-8. Braff DL, Geyer MA, Light GA, Sprock J, Perry W, Cadenhead KS, Swerdlow NR. PMID: 11343875.
      View in: PubMed   Mentions: 108     Fields:    Translation:Humans
    184. Schizophrenia patients demonstrate a dissociation on declarative and non-declarative memory tests. Schizophr Res. 2000 Dec 15; 46(2-3):167-74. Perry W, Light GA, Davis H, Braff DL. PMID: 11120428.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    185. Normal P50 suppression in schizophrenia patients treated with atypical antipsychotic medications. Am J Psychiatry. 2000 May; 157(5):767-71. Light GA, Geyer MA, Clementz BA, Cadenhead KS, Braff DL. PMID: 10784470.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    186. Do self-reports of perceptual anomalies reflect gating deficits in schizophrenia patients? Biol Psychiatry. 2000 Mar 01; 47(5):463-7. Light GA, Braff DL. PMID: 10704957.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    187. Sensory gating deficits assessed by the P50 event-related potential in subjects with schizotypal personality disorder. Am J Psychiatry. 2000 Jan; 157(1):55-9. Cadenhead KS, Light GA, Geyer MA, Braff DL. PMID: 10618013.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    188. Human and animal studies of schizophrenia-related gating deficits. Curr Psychiatry Rep. 1999 Oct; 1(1):31-40. Light GA, Braff DL. PMID: 11122903.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimals
    189. Amphetamine disrupts P50 suppression in normal subjects. Biol Psychiatry. 1999 Oct 01; 46(7):990-6. Light GA, Malaspina D, Geyer MA, Luber BM, Coleman EA, Sackeim HA, Braff DL. PMID: 10509182.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    190. The "incredible shrinking" P50 event-related potential. Biol Psychiatry. 1998 Jun 15; 43(12):918-20. Light GA, Braff DL. PMID: 9627748.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    191. Clinical impressions of the value of Darvon injectable. Anesth Analg. 1965 Nov-Dec; 44(6):722-5. Light GA, Fini RA. PMID: 5321190.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCTClinical Trials
    192. A NEW VASOCONSTRICTOR: PRELIMINARY STUDIES OF PHELYPRESSIN. Anesth Analg. 1965 May-Jun; 44:280-7. LIGHT GA, RATTENBORG C, HOLADAY DA. PMID: 14297319.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    193. HISTORY, PHARMACOLOGY AND CLINICAL USE OF ETHYLENE. Clin Anesth. 1964; 3:135-50. LIGHT GA. PMID: 14120105.
      View in: PubMed   Mentions:    Fields:    
    194. Methoxyflurane anesthesia: a clinical appraisal. Anesth Analg. 1962 Mar-Apr; 41:225-9. THOMASON R, LIGHT G, HOLADAY DA. PMID: 13920842.
      View in: PubMed   Mentions: 3     Fields:    
    195. Effects of pressure breathing on the peripheral circulation: motion picture observations in the bat wing and rabbit ear chamber. Arch Surg. 1959 Sep; 79:493-6. MOERCH ET, ENGEL R, LIGHT GA. PMID: 14423191.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    196. Promethazine (phenergan) hydrochloride as an adjunct to anesthesia; preliminary clinical and animal studies. J Am Med Assoc. 1957 Aug 10; 164(15):1648-50. LIGHT GA, MORCH ET, ENGEL R, CUNNINGHAM JJ. PMID: 13448916.
      View in: PubMed   Mentions: 1  
    197. Music in surgery. Curr Res Anesth Analg. 1954 Jul-Aug; 33(4):258-64. LIGHT GA, LOVE DM, BENSON D, MORCH ET. PMID: 13182832.
      View in: PubMed   Mentions: 1  Translation:Humans
    198. Resume of anesthetic experience in 1037 intrathoracic operations. Curr Res Anesth Analg. 1950 Nov-Dec; 29(6):301-14. LIGHT GA, LIVINGSTONE HM, ADAMS WE. PMID: 14783921.
      View in: PubMed   Mentions: Translation:Humans
    199. Anesthesia for operations on the heart and great vessels. Arch Surg (1920). 1950 Jan; 60(1):42-54. LIGHT GA, LIVINGSTONE HM, ADAMS WE. PMID: 15399391.
      View in: PubMed   Mentions:
    200. Use of magnetic recorder silent music during operation. Curr Res Anesth Analg. 1949 Nov-Dec; 28(6):330-8. LIGHT GA, HAYMOND WV, et al. PMID: 15407043.
      View in: PubMed   Mentions: Translation:Humans
    201. Anesthesia for extremity amputations; a statistical review of 185 major amputation cases. Am J Surg. 1949 Aug; 78(2):220-5. PETERS MP, BROBERG GR, LIGHT GA. PMID: 18135637.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    202. A record for the recovery room. Hospitals. 1949 Jun; 23(6 Pt. 1):60. LIVINGSTONE HM, LIGHT GA. PMID: 18130600.
      View in: PubMed   Mentions:    Fields:    
    203. Rectal sodium pentothal in 2,500 anesthesias. Curr Res Anesth Analg. 1948 Nov-Dec; 27(6):343-50. WEINSTEIN ML, LIGHT GA. PMID: 18893457.
      View in: PubMed   Mentions: Translation:Humans
    204. Anesthetic mortality in intrathoracic surgery. Arch Surg (1920). 1947 Nov; 55(5):545-56. LIVINGSTONE H, LIGHT G, et al. PMID: 20271749.
      View in: PubMed   Mentions: Translation:Humans
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