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Arpi Minassian

Title(s)Clinical Professor, Psychiatry
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Biography

    Dr. Minassian received her doctorate from the California School of Professional Psychology-San Diego. She completed her predoctoral internship in the UCSD Psychology Internship Training Program and continued at UCSD as a post-doctoral fellow in the NIMH Fellowship in Biological Psychiatry and Neuroscience. She joined the faculty of the Department of Psychiatry as an Assistant Project Scientist in July of 2004 and is currently a Clinical Professor. Her research laboratory is located on the inpatient Neuropsychiatry and Behavioral Medicine Service at the UCSD Medical Center in Hillcrest. She also serves a faculty psychologist at the Medical Center and a clinical supervisor in the Psychology Internship Training Program.

    Research Interests

    Dr. Minassian’s research program is focused upon understanding the relationship between biology and behavior in mental illness, medical illness, and substance abuse. Much of her research has implemented physiological and cognitive paradigms to understand brain dysfunction in psychiatric populations such as bipolar disorder, schizophrenia, PTSD, and substance addiction as well as neuromedical conditions such as HIV. The methodologies she has helped develop and implement can be translated to animals, an application which accelerates our understanding of biological mechanisms. She serves as Project Director in UCSD’s Translational Methamphetamine AIDS Research Center (TMARC) where she and her colleagues are studying decision making in HIV, methamphetamine dependence, and aging in humans and in rodent models. She is also a co-investigator on a number of NIH-funded studies of inhibitory and cognitive deficits in bipolar disorder. Dr. Minassian is a clinical psychologist and an attending clinician in the UCSD Health Systems. Her clinical area of expertise is consultation-liaison and she works with medically ill patients on the Burn Service, in the Pulmonary Rehabilitation Program, as well as with individuals with chronic pain and those awaiting organ transplantation. Furthermore she conducts clinical research with an interdisciplinary group of academicians outside the department of Psychiatry (e.g., Bariatric Surgery, Burn Surgery and Emergency Medicine). She is a member of the department’s Diversity Committee and also serves on university- and hospital-wide diversity focus groups.

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    Translational Methamphetamine AIDS Research Center (TMARC)
    NIH P50DA026306Dec 1, 2008 - Dec 31, 2019
    Role: Co-Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Effects of Cannabis Use on Cognitive Function in Healthy Aging: A Systematic Scoping Review. Arch Clin Neuropsychol. 2020 Nov 07. Pocuca N, Walter TJ, Minassian A, Young JW, Geyer MA, Perry W. PMID: 33159510.
      View in: PubMed   Mentions:    Fields:    
    2. Both HIV and Tat expression decrease prepulse inhibition with further impairment by methamphetamine. Prog Neuropsychopharmacol Biol Psychiatry. 2021 Mar 02; 106:110089. Walter TJ, Young JW, Milienne-Petiot M, Deben DS, Heaton RK, Letendre S, Grelotti DJ, Perry W, Grant I, Minassian A. PMID: 32891668.
      View in: PubMed   Mentions:    Fields:    
    3. Sustained attention and vigilance deficits associated with HIV and a history of methamphetamine dependence. Drug Alcohol Depend. 2020 10 01; 215:108245. Pocuca N, Young JW, MacQueen DA, Letendre S, Heaton RK, Geyer MA, Perry W, Grant I, Minassian A. PMID: 32871507.
      View in: PubMed   Mentions:    Fields:    
    4. Convergent neural substrates of inattention in bipolar disorder patients and dopamine transporter-deficient mice using the 5-choice CPT. Bipolar Disord. 2020 02; 22(1):46-58. Young JW, Geyer MA, Halberstadt AL, van Enkhuizen J, Minassian A, Khan A, Perry W, Eyler LT. PMID: 31025493.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Heart rate variability and emotion regulation among individuals with obesity and loss of control eating. Physiol Behav. 2019 02 01; 199:73-78. Godfrey KM, Juarascio A, Manasse S, Minassian A, Risbrough V, Afari N. PMID: 30414883.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    6. Amphetamine improves mouse and human attention in the 5-choice continuous performance test. Neuropharmacology. 2018 08; 138:87-96. MacQueen DA, Minassian A, Kenton JA, Geyer MA, Perry W, Brigman JL, Young JW. PMID: 29859849.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    7. The COMT Val158Met Polymorphism and Exploratory Behavior in Bipolar Mania. Mol Neuropsychiatry. 2018 Feb; 3(3):151-156. Minassian A, Young JW, Geyer MA, Kelsoe JR, Perry W. PMID: 29594134.
      View in: PubMed   Mentions:
    8. Everyday functional ability in HIV and methamphetamine dependence. Drug Alcohol Depend. 2017 06 01; 175:60-66. Minassian A, Henry BL, Iudicello JE, Morgan EE, Letendre SL, Heaton RK, Perry W. PMID: 28399475.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    9. Amphetamine increases activity but not exploration in humans and mice. Psychopharmacology (Berl). 2016 Jan; 233(2):225-33. Minassian A, Young JW, Cope ZA, Henry BL, Geyer MA, Perry W. PMID: 26449721.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    10. Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 2015 Oct; 72(10):979-86. Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer MA, Risbrough VB, . PMID: 26353072.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    11. Prepulse inhibition in HIV-associated neurocognitive disorders. J Int Neuropsychol Soc. 2013 Jul; 19(6):709-17. Minassian A, Henry BL, Woods SP, Vaida F, Grant I, Geyer MA, Perry W, . PMID: 23552464.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    12. Repeated assessment of exploration and novelty seeking in the human behavioral pattern monitor in bipolar disorder patients and healthy individuals. PLoS One. 2011; 6(8):e24185. Minassian A, Henry BL, Young JW, Masten V, Geyer MA, Perry W. PMID: 21912623.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    13. The quantitative assessment of motor activity in mania and schizophrenia. J Affect Disord. 2010 Jan; 120(1-3):200-6. Minassian A, Henry BL, Geyer MA, Paulus MP, Young JW, Perry W. PMID: 19435640.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    14. Adults with autism show increased sensitivity to outcomes at low error rates during decision-making. J Autism Dev Disord. 2007 Aug; 37(7):1279-88. Minassian A, Paulus M, Lincoln A, Perry W. PMID: 17080271.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    15. The relationship between sensorimotor gating and clinical improvement in acutely ill schizophrenia patients. Schizophr Res. 2007 Jan; 89(1-3):225-31. Minassian A, Feifel D, Perry W. PMID: 17005374.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    16. Visual scanning deficits in schizophrenia and their relationship to executive functioning impairment. Schizophr Res. 2005 Apr 01; 74(1):69-79. Minassian A, Granholm E, Verney S, Perry W. PMID: 15694756.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    17. Increased sensitivity to error during decision-making in bipolar disorder patients with acute mania. J Affect Disord. 2004 Oct 15; 82(2):203-8. Minassian A, Paulus MP, Perry W. PMID: 15488248.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    18. Pupillary dilation to simple vs. complex tasks and its relationship to thought disturbance in schizophrenia patients. Int J Psychophysiol. 2004 Mar; 52(1):53-62. Minassian A, Granholm E, Verney S, Perry W. PMID: 15003372.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCTClinical Trials
    19. The category test perseveration, loss of set, and memory scales: three new scales and their relationship to executive functioning measures. Assessment. 2003 Sep; 10(3):213-21. Minassian A, Perry W, Carlson M, Pelham M, DeFilippis N. PMID: 14503644.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
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