Jean Wang

Title(s)Recall Faculty, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    FEN1 Endonuclease as a Synthetic Lethal Target for Cancer Therapy
    NIH R01CA255341Aug 15, 2021 - Jul 31, 2026
    Role: Co-Principal Investigator
    FEN1-Nuclease-Targeted Therapy for Ewing Sarcoma
    NIH R01CA251414Apr 1, 2021 - Mar 31, 2026
    Role: Co-Principal Investigator
    Protein Tyrosine Kinases in Leiomyomata Uteri
    NIH R01HD046225Sep 26, 2003 - Jul 31, 2009
    Role: Principal Investigator
    Integrin Signaling in Hemostasis and Blood Diseases
    NIH P01HL057900Apr 1, 1997 - Jan 31, 2014
    Role: Co-Investigator
    Cancer Biology, Informatics & Omics (CBIO) Training Program
    NIH T32CA067754Sep 25, 1995 - Jun 30, 2022
    Role: Co-Principal Investigator
    Biological Function of the Retinoblastoma Gene Product
    NIH R01CA058320May 1, 1992 - Feb 28, 2014
    Role: Principal Investigator
    FUNCTION OF NUCLEAR ONCOGENES IN CANCER CELLS
    NIH P01CA050528Sep 8, 1989 - Jan 31, 1998
    Role: Co-Investigator
    Nuclear Function of Abl in DNA Damage Response
    NIH R01CA043054Aug 1, 1986 - Nov 30, 2019
    Role: Principal Investigator
    Nuclear Function of the c-Abl Protooncoprotien
    NIH R37CA043054Aug 1, 1986 - Feb 25, 2008
    Role: Principal Investigator
    BASIC BIOCHEMICAL AND BIOLOGICAL MECHANISMS IN CANCER
    NIH T32CA009345Aug 1, 1984 - Nov 30, 2000
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination. Proc Natl Acad Sci U S A. 2020 08 11; 117(32):19415-19424. Guo E, Ishii Y, Mueller J, Srivatsan A, Gahman T, Putnam CD, Wang JYJ, Kolodner RD. PMID: 32719125; PMCID: PMC7431096.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    2. Cell Death Response to DNA Damage. Yale J Biol Med. 2019 12; 92(4):771-779. Wang JYJ. PMID: 31866794; PMCID: PMC6913835.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimalsCells
    3. DNA damage-induced cell death relies on SLFN11-dependent cleavage of distinct type II tRNAs. Nat Struct Mol Biol. 2018 11; 25(11):1047-1058. Li M, Kao E, Malone D, Gao X, Wang JYJ, David M. PMID: 30374083; PMCID: PMC6579113.
      View in: PubMed   Mentions: 58     Fields:    Translation:HumansCells
    4. Nuclear respiratory factor 1 promotes spheroid survival and mesenchymal transition in mammary epithelial cells. Oncogene. 2018 11; 37(47):6152-6165. Zhou Y, Xu Z, Quan D, Zhang F, Zhang H, Xiao T, Hou S, Qiao H, Harismendy O, Wang JYJ, Suo G. PMID: 29995872; PMCID: PMC6329670.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    5. Extracellular vesicles transfer nuclear Abl-dependent and radiation-induced miR-34c into unirradiated cells to cause bystander effects. Mol Biol Cell. 2018 09 01; 29(18):2228-2242. Rastogi S, Hwang A, Chan J, Wang JYJ. PMID: 29975106; PMCID: PMC6249796.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    6. Loss of histone variant macroH2A2 expression associates with progression of anal neoplasm. J Clin Pathol. 2016 Jul; 69(7):627-31. Hu WH, Miyai K, Sporn JC, Luo L, Wang JY, Cosman B, Ramamoorthy S. PMID: 26658220; PMCID: PMC4941135.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    7. EnABLing microprocessor for apoptosis. Mol Cell Oncol. 2016; 3(2). Tu CC, Wang JY. PMID: 27182551; PMCID: PMC4866609.
      View in: PubMed   Mentions:
    8. Discovery of survival factor for primitive chronic myeloid leukemia cells using induced pluripotent stem cells. Stem Cell Res. 2015 Nov; 15(3):678-693. Suknuntha K, Ishii Y, Tao L, Hu K, McIntosh BE, Yang D, Swanson S, Stewart R, Wang JYJ, Thomson J, Slukvin I. PMID: 26561938; PMCID: PMC5003778.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    9. Proteomics studies of the interactome of RNA polymerase II C-terminal repeated domain. BMC Res Notes. 2015 Oct 29; 8:616. Pineda G, Shen Z, de Albuquerque CP, Reynoso E, Chen J, Tu CC, Tang W, Briggs S, Zhou H, Wang JY. PMID: 26515650; PMCID: PMC4627417.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    10. Knockout Serum Replacement Promotes Cell Survival by Preventing BIM from Inducing Mitochondrial Cytochrome C Release. PLoS One. 2015; 10(10):e0140585. Ishii Y, Nhiayi MK, Tse E, Cheng J, Massimino M, Durden DL, Vigneri P, Wang JY. PMID: 26473951; PMCID: PMC4608728.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    11. The kinase ABL phosphorylates the microprocessor subunit DGCR8 to stimulate primary microRNA processing in response to DNA damage. Sci Signal. 2015 Jun 30; 8(383):ra64. Tu CC, Zhong Y, Nguyen L, Tsai A, Sridevi P, Tarn WY, Wang JY. PMID: 26126715; PMCID: PMC4499470.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    12. Induction of TAp73 by platinum-based compounds to overcome drug resistance in p53 dysfunctional chronic lymphocytic leukemia. Leuk Lymphoma. 2015; 56(8):2439-47. Tonino SH, Mulkens CE, van Laar J, Derks IA, Suo G, Croon-de Boer F, van Oers MH, Eldering E, Wang JY, Kater AP. PMID: 25511680; PMCID: PMC4592483.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    13. Indispensable functions of ABL and PDGF receptor kinases in epithelial adherence of attaching/effacing pathogens under physiological conditions. Am J Physiol Cell Physiol. 2014 Jul 15; 307(2):C180-9. Manthey CF, Calabio CB, Wosinski A, Hanson EM, Vallance BA, Groisman A, Martín MG, Wang JY, Eckmann L. PMID: 24848114; PMCID: PMC4101622.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    14. Telomerase expression abrogates rapamycin-induced irreversible growth arrest of uterine fibroid smooth muscle cells. Reprod Sci. 2014 Sep; 21(9):1161-70. Suo G, Sadarangani A, Tang W, Cowan BD, Wang JY. PMID: 24784716; PMCID: PMC4212341.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    15. S-score: a scoring system for the identification and prioritization of predicted cancer genes. PLoS One. 2014; 9(4):e94147. de Souza JE, Fonseca AF, Valieris R, Carraro DM, Wang JY, Kolodner RD, de Souza SJ. PMID: 24710071; PMCID: PMC3978018.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    16. The capable ABL: what is its biological function? Mol Cell Biol. 2014 Apr; 34(7):1188-97. Wang JY. PMID: 24421390; PMCID: PMC3993570.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    17. Persistent inhibition of ABL tyrosine kinase causes enhanced apoptotic response to TRAIL and disrupts the pro-apoptotic effect of chloroquine. PLoS One. 2013; 8(10):e77495. Sridevi P, Nhiayi MK, Setten RL, Wang JY. PMID: 24147007; PMCID: PMC3795698.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    18. Trp53 deficiency protects against acute intestinal inflammation. J Immunol. 2013 Jul 15; 191(2):837-47. Spehlmann ME, Manthey CF, Dann SM, Hanson E, Sandhu SS, Liu LY, Abdelmalak FK, Diamanti MA, Retzlaff K, Scheller J, Rose-John S, Greten FR, Wang JY, Eckmann L. PMID: 23772033; PMCID: PMC3710108.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    19. Colon cancer cells adopt an invasive phenotype without mesenchymal transition in 3-D but not 2-D culture upon combined stimulation with EGF and crypt growth factors. BMC Cancer. 2013 May 02; 13:221. Ludwig K, Tse ES, Wang JY. PMID: 23638973; PMCID: PMC3667045.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    20. Nuclear expression of β-catenin promotes RB stability and resistance to TNF-induced apoptosis in colon cancer cells. Mol Cancer Res. 2013 Mar; 11(3):207-18. Han J, Soletti RC, Sadarangani A, Sridevi P, Ramirez ME, Eckmann L, Borges HL, Wang JY. PMID: 23339186; PMCID: PMC4191841.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    21. β-Catenin-dependent lysosomal targeting of internalized tumor necrosis factor-α suppresses caspase-8 activation in apoptosis-resistant colon cancer cells. Mol Biol Cell. 2013 Feb; 24(4):465-73. Han J, Sridevi P, Ramirez M, Ludwig KJ, Wang JY. PMID: 23264463; PMCID: PMC3571869.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    22. Detection of early Abl kinase activation after ionizing radiation by using a peptide biosensor. Chembiochem. 2012 Mar 19; 13(5):665-73. Tang J, Wang JY, Parker LL. PMID: 22334513; PMCID: PMC3429332.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    23. Checking before changing: cell cycle checkpoints inhibit muscle differentiation. Cell Cycle. 2011 Oct 01; 10(19):3234-5. Wang JY. PMID: 21946520; PMCID: PMC5606196.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    24. RB restricts DNA damage-initiated tumorigenesis through an LXCXE-dependent mechanism of transcriptional control. Mol Cell. 2011 Aug 19; 43(4):663-72. Bourgo RJ, Thangavel C, Ertel A, Bergseid J, McClendon AK, Wilkens L, Witkiewicz AK, Wang JY, Knudsen ES. PMID: 21855804; PMCID: PMC4271833.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    25. Priming and potentiation of DNA damage response by fibronectin in human colon cancer cells and tumor-derived myofibroblasts. Int J Oncol. 2011 Aug; 39(2):393-400. DE Wever O, Sobczak-Thépot J, Vercoutter-Edouart AS, Michalski JC, Ouelaa-Benslama R, Stupack DG, Bracke M, Wang JYJ, Gespach C, Emami S. PMID: 21567080; PMCID: PMC5003111.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    26. Uracil DNA N-glycosylase promotes assembly of human centromere protein A. PLoS One. 2011 Mar 02; 6(3):e17151. Zeitlin SG, Chapados BR, Baker NM, Tai C, Slupphaug G, Wang JY. PMID: 21399697; PMCID: PMC3047565.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    27. Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL. PLoS One. 2011 Feb 11; 6(2):e17020. Preyer M, Vigneri P, Wang JY. PMID: 21347248; PMCID: PMC3037956.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    28. An evolutionarily acquired genotoxic response discriminates MyoD from Myf5, and differentially regulates hypaxial and epaxial myogenesis. EMBO Rep. 2011 Feb; 12(2):164-71. Innocenzi A, Latella L, Messina G, Simonatto M, Marullo F, Berghella L, Poizat C, Shu CW, Wang JY, Puri PL, Cossu G. PMID: 21212806; PMCID: PMC3049428.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    29. Expression profiling of protein tyrosine kinases and their ligand activators in leiomyoma uteri. Syst Biol Reprod Med. 2010 Aug; 56(4):318-26. Jiang Y, Suo G, Sadarangani A, Cowan B, Wang JY. PMID: 20462350.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    30. Targeting the RB-pathway in cancer therapy. Clin Cancer Res. 2010 Feb 15; 16(4):1094-9. Knudsen ES, Wang JY. PMID: 20145169; PMCID: PMC2822892.
      View in: PubMed   Mentions: 101     Fields:    Translation:HumansCells
    31. Double-strand DNA breaks recruit the centromeric histone CENP-A. Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37):15762-7. Zeitlin SG, Baker NM, Chapados BR, Soutoglou E, Wang JY, Berns MW, Cleveland DW. PMID: 19717431; PMCID: PMC2747192.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansAnimalsCells
    32. Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73. BMC Biol. 2009 Jun 26; 7:35. Huang V, Lu X, Jiang Y, Wang JY. PMID: 19558638; PMCID: PMC2711048.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    33. Platelet-derived growth factor C is upregulated in human uterine fibroids and regulates uterine smooth muscle cell growth. Biol Reprod. 2009 Oct; 81(4):749-58. Suo G, Jiang Y, Cowan B, Wang JY. PMID: 19553600; PMCID: PMC2754888.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    34. Murine xenograft model for human uterine fibroids: an in vivo imaging approach. Reprod Sci. 2009 Sep; 16(9):827-42. Suo G, Sadarangani A, Lamarca B, Cowan B, Wang JY. PMID: 19516078.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    35. A functional connection between pRB and transforming growth factor beta in growth inhibition and mammary gland development. Mol Cell Biol. 2009 Aug; 29(16):4455-66. Francis SM, Bergsied J, Isaac CE, Coschi CH, Martens AL, Hojilla CV, Chakrabarti S, Dimattia GE, Khoka R, Wang JY, Dick FA. PMID: 19506017; PMCID: PMC2725731.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    36. The CML stem cell: evolution of the progenitor. Cell Cycle. 2009 May 01; 8(9):1338-43. Stuart SA, Minami Y, Wang JY. PMID: 19342894; PMCID: PMC2792634.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    37. Exploiting the promiscuity of imatinib. J Biol. 2009; 8(3):30. Lee SJ, Wang JY. PMID: 19435483; PMCID: PMC2689438.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    38. Ionizing radiation induces ATM-independent degradation of p21Cip1 in transformed cells. J Biol Chem. 2009 May 29; 284(22):15061-70. Stuart SA, Wang JY. PMID: 19332548; PMCID: PMC2685688.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    39. Retention but significant reduction of BCR-ABL transcript in hematopoietic stem cells in chronic myelogenous leukemia after imatinib therapy. Int J Hematol. 2008 Dec; 88(5):471-475. Abe A, Minami Y, Hayakawa F, Kitamura K, Nomura Y, Murata M, Katsumi A, Kiyoi H, Jamieson CHM, Wang JYJ, Naoe T. PMID: 19039626; PMCID: PMC2626150.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    40. BCR-ABL-transformed GMP as myeloid leukemic stem cells. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17967-72. Minami Y, Stuart SA, Ikawa T, Jiang Y, Banno A, Hunton IC, Young DJ, Naoe T, Murre C, Jamieson CH, Wang JY. PMID: 19004799; PMCID: PMC2582213.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    41. Induction of cell retraction by the combined actions of Abl-CrkII and Rho-ROCK1 signaling. J Cell Biol. 2008 Nov 17; 183(4):711-23. Huang X, Wu D, Jin H, Stupack D, Wang JY. PMID: 19001122; PMCID: PMC2582888.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    42. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13993-8. Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, Avdievich E, Hunton IC, Kolodner RD, Edelmann W, Wang JY. PMID: 18768816; PMCID: PMC2528866.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    43. Akt inhibitor a-443654 interferes with mitotic progression by regulating aurora a kinase expression. Neoplasia. 2008 Aug; 10(8):828-37. Liu X, Shi Y, Woods KW, Hessler P, Kroeger P, Wilsbacher J, Wang J, Wang JY, Li C, Li Q, Rosenberg SH, Giranda VL, Luo Y. PMID: 18670641; PMCID: PMC2481570.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    44. Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion. BMC Syst Biol. 2008 Jun 13; 2:49. Huang X, Wang JY, Lu X. PMID: 18549508; PMCID: PMC2441606.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    45. DNA damage-induced cell death: lessons from the central nervous system. Cell Res. 2008 Jan; 18(1):17-26. Borges HL, Linden R, Wang JY. PMID: 18087290; PMCID: PMC2626635.
      View in: PubMed   Mentions: 55     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    46. Blockade of tumor necrosis factor-induced Bid cleavage by caspase-resistant Rb. J Biol Chem. 2007 Oct 05; 282(40):29401-13. Huang X, Masselli A, Frisch SM, Hunton IC, Jiang Y, Wang JY. PMID: 17686781.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    47. Abl tyrosine kinase promotes dorsal ruffles but restrains lamellipodia extension during cell spreading on fibronectin. Mol Biol Cell. 2007 Oct; 18(10):4143-54. Jin H, Wang JY. PMID: 17686996; PMCID: PMC1995715.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    48. An evolutionarily conserved mechanism delimiting SHR movement defines a single layer of endodermis in plants. Science. 2007 Apr 20; 316(5823):421-5. Cui H, Levesque MP, Vernoux T, Jung JW, Paquette AJ, Gallagher KL, Wang JY, Blilou I, Scheres B, Benfey PN. PMID: 17446396.
      View in: PubMed   Mentions: 248     Fields:    Translation:AnimalsCells
    49. Separation of anti-proliferation and anti-apoptotic functions of retinoblastoma protein through targeted mutations of its A/B domain. PLoS One. 2006 Dec 20; 1:e82. Chau BN, Pan CW, Wang JY. PMID: 17183714; PMCID: PMC1762320.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    50. Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics. Int J Cancer. 2006 Dec 15; 119(12):2784-94. Chen Z, Xiao Z, Gu WZ, Xue J, Bui MH, Kovar P, Li G, Wang G, Tao ZF, Tong Y, Lin NH, Sham HL, Wang JY, Sowin TJ, Rosenberg SH, Zhang H. PMID: 17019715.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansCells
    51. Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage. Mol Cell Biol. 2006 Sep; 26(18):6859-69. Chao C, Wu Z, Mazur SJ, Borges H, Rossi M, Lin T, Wang JY, Anderson CW, Appella E, Xu Y. PMID: 16943427; PMCID: PMC1592865.
      View in: PubMed   Mentions: 60     Fields:    Translation:AnimalsCells
    52. Eph tumour suppression: the dark side of Gleevec. Nat Cell Biol. 2006 Aug; 8(8):785-6. Wang JY. PMID: 16880809.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    53. Mismatch repair proteins as sensors of alkylation DNA damage. Cancer Cell. 2006 Jun; 9(6):417-8. Wang JY, Edelmann W. PMID: 16766259.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    54. CD154 induces p73 to overcome the resistance to apoptosis of chronic lymphocytic leukemia cells lacking functional p53. Blood. 2006 Nov 15; 108(10):3450-7. Dicker F, Kater AP, Prada CE, Fukuda T, Castro JE, Sun G, Wang JY, Kipps TJ. PMID: 16741250; PMCID: PMC1895435.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    55. Tumor promotion by caspase-resistant retinoblastoma protein. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15587-92. Borges HL, Bird J, Wasson K, Cardiff RD, Varki N, Eckmann L, Wang JY. PMID: 16227443; PMCID: PMC1255734.
      View in: PubMed   Mentions: 15     Fields:    Translation:Animals
    56. cAMP-mediated inhibition of DNA replication and S phase progression: involvement of Rb, p21Cip1, and PCNA. Mol Biol Cell. 2005 Mar; 16(3):1527-42. Naderi S, Wang JY, Chen TT, Gutzkow KB, Blomhoff HK. PMID: 15647383; PMCID: PMC551513.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    57. Mitotic phosphorylation rescues Abl from F-actin-mediated inhibition. J Biol Chem. 2005 Mar 18; 280(11):10318-25. Woodring PJ, Hunter T, Wang JY. PMID: 15632178.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    58. Nucleo-cytoplasmic communication in apoptotic response to genotoxic and inflammatory stress. Cell Res. 2005 Jan; 15(1):43-8. Wang JY. PMID: 15686626.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    59. Ectopic expression of p73alpha, but not p73beta, suppresses myogenic differentiation. J Biol Chem. 2005 Jan 21; 280(3):2159-64. Li CY, Zhu J, Wang JY. PMID: 15545283.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    60. c-Abl phosphorylates Dok1 to promote filopodia during cell spreading. J Cell Biol. 2004 May 24; 165(4):493-503. Woodring PJ, Meisenhelder J, Johnson SA, Zhou GL, Field J, Shah K, Bladt F, Pawson T, Niki M, Pandolfi PP, Wang JY, Hunter T. PMID: 15148308; PMCID: PMC2172353.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    61. Tumor necrosis factor alpha-induced apoptosis requires p73 and c-ABL activation downstream of RB degradation. Mol Cell Biol. 2004 May; 24(10):4438-47. Chau BN, Chen TT, Wan YY, DeGregori J, Wang JY. PMID: 15121862; PMCID: PMC400462.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    62. Controlling Abl: auto-inhibition and co-inhibition? Nat Cell Biol. 2004 Jan; 6(1):3-7. Wang JY. PMID: 14704671.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    63. Coordination of repair, checkpoint, and cell death responses to DNA damage. Adv Protein Chem. 2004; 69:101-35. Wang JY, Cho SK. PMID: 15588841.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    64. Death by Abl: a matter of location. Curr Top Dev Biol. 2004; 59:165-92. Zhu J, Wang JY. PMID: 14975251.
      View in: PubMed   Mentions: 16     Fields:    Translation:AnimalsCells
    65. Modulation of DNA damage-induced apoptosis by cell adhesion is independently mediated by p53 and c-Abl. Proc Natl Acad Sci U S A. 2003 Sep 02; 100(18):10281-6. Truong T, Sun G, Doorly M, Wang JY, Schwartz MA. PMID: 12928501; PMCID: PMC193552.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansAnimalsCells
    66. Modulation of human checkpoint kinase Chk1 by the regulatory beta-subunit of protein kinase CK2. Oncogene. 2003 Aug 07; 22(32):4933-42. Guerra B, Issinger OG, Wang JY. PMID: 12902976.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    67. Regulation of F-actin-dependent processes by the Abl family of tyrosine kinases. J Cell Sci. 2003 Jul 01; 116(Pt 13):2613-26. Woodring PJ, Hunter T, Wang JY. PMID: 12775773.
      View in: PubMed   Mentions: 92     Fields:    Translation:HumansAnimalsCells
    68. Exclusion of c-Abl from the nucleus restrains the p73 tumor suppression function. J Biol Chem. 2003 Jul 04; 278(27):25151-7. Vella V, Zhu J, Frasca F, Li CY, Vigneri P, Vigneri R, Wang JY. PMID: 12716888.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    69. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2420-5. Shimodaira H, Yoshioka-Yamashita A, Kolodner RD, Wang JY. PMID: 12601175; PMCID: PMC151356.
      View in: PubMed   Mentions: 56     Fields:    Translation:HumansAnimalsCells
    70. Coordinated regulation of life and death by RB. Nat Rev Cancer. 2003 Feb; 3(2):130-8. Chau BN, Wang JY. PMID: 12563312.
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