Webster Cavenee

Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Noninvasive therapy of brain cancer using a unique systemic delivery methodology with a cancer terminator virus. J Cell Physiol. 2024 Aug; 239(8):e31302. Bhoopathi P, Mannangatti P, Pradhan AK, Kumar A, Maji S, Lang FF, Klibanov AL, Madan E, Cavenee WK, Keoprasert T, Sun D, Bjerkvig R, Thorsen F, Gogna R, Das SK, Emdad L, Fisher PB. PMID: 38775127.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. DNA hypomethylator phenotype reprograms glutamatergic network in receptor tyrosine kinase gene-mutated glioblastoma. Acta Neuropathol Commun. 2024 Mar 13; 12(1):40. Harachi M, Masui K, Shimizu E, Murakami K, Onizuka H, Muragaki Y, Kawamata T, Nakayama H, Miyata M, Komori T, Cavenee WK, Mischel PS, Kurata A, Shibata N. PMID: 38481314; PMCID: PMC10935831.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    3. MDA-9/Syntenin in the tumor and microenvironment defines prostate cancer bone metastasis. Proc Natl Acad Sci U S A. 2023 Nov 07; 120(45):e2307094120. Maji S, Pradhan AK, Kumar A, Bhoopathi P, Mannangatti P, Guo C, Windle JJ, Subler MA, Wang XY, Semmes OJ, Nyalwidhe JO, Mukhopadhyay N, Paul AK, Hatfield B, Levit MM, Madan E, Sarkar D, Emdad L, Cohen DJ, Gogna R, Cavenee WK, Das SK, Fisher PB. PMID: 37922327; PMCID: PMC10636346.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    4. Dysregulation of the PRUNE2/PCA3 genetic axis in human prostate cancer: from experimental discovery to validation in two independent patient cohorts. Elife. 2023 01 16; 12. Lauer RC, Barry M, Smith TL, Thomas AM, Wu J, Du R, Lee JH, Rao A, Dobroff AS, Arap MA, Nunes DN, Silva IT, Dias-Neto E, Chen I, McCance DJ, Cavenee WK, Pasqualini R, Arap W. PMID: 36645410; PMCID: PMC9886275.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    5. Somatic 9p24.1 alterations in HPV- head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity. Proc Natl Acad Sci U S A. 2022 11 22; 119(47):e2213835119. Zhao X, Cohen EEW, William WN, Bianchi JJ, Abraham JP, Magee D, Spetzler DB, Gutkind JS, Alexandrov LB, Cavenee WK, Lippman SM, Davoli T. PMID: 36395141; PMCID: PMC9704728.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    6. The metabolomic landscape plays a critical role in glioma oncogenesis. Cancer Sci. 2022 May; 113(5):1555-1563. Masui K, Cavenee WK, Mischel PS, Shibata N. PMID: 35271755; PMCID: PMC9128185.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    7. Insights into the Mechanisms of Action of MDA-7/IL-24: A Ubiquitous Cancer-Suppressing Protein. Int J Mol Sci. 2021 Dec 22; 23(1). Modi J, Roy A, Pradhan AK, Kumar A, Talukdar S, Bhoopathi P, Maji S, Mannangatti P, Sanchez De La Rosa D, Li J, Guo C, Subler MA, Windle JJ, Cavenee WK, Sarkar D, Wang XY, Das SK, Emdad L, Fisher PB. PMID: 35008495; PMCID: PMC8744595.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    8. Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1β. Proc Natl Acad Sci U S A. 2021 05 25; 118(21). Pradhan AK, Maji S, Bhoopathi P, Talukdar S, Mannangatti P, Guo C, Wang XY, Cartagena LC, Idowu M, Landry JW, Sarkar D, Emdad L, Cavenee WK, Das SK, Fisher PB. PMID: 34016751; PMCID: PMC8166168.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimalsCells
    9. Immune evasion in HPV- head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss. Proc Natl Acad Sci U S A. 2021 05 11; 118(19). William WN, Zhao X, Bianchi JJ, Lin HY, Cheng P, Lee JJ, Carter H, Alexandrov LB, Abraham JP, Spetzler DB, Dubinett SM, Cleveland DW, Cavenee W, Davoli T, Lippman SM. PMID: 33952700; PMCID: PMC8126856.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCells
    10. Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer. Metabolites. 2021 Apr 01; 11(4). Harachi M, Masui K, Cavenee WK, Mischel PS, Shibata N. PMID: 33916219; PMCID: PMC8066013.
      View in: PubMed   Mentions: 13  
    11. A Mathematical Model to Estimate Chemotherapy Concentration at the Tumor-Site and Predict Therapy Response in Colorectal Cancer Patients with Liver Metastases. Cancers (Basel). 2021 Jan 25; 13(3). Anaya DA, Dogra P, Wang Z, Haider M, Ehab J, Jeong DK, Ghayouri M, Lauwers GY, Thomas K, Kim R, Butner JD, Nizzero S, Ramírez JR, Plodinec M, Sidman RL, Cavenee WK, Pasqualini R, Arap W, Fleming JB, Cristini V. PMID: 33503971; PMCID: PMC7866038.
      View in: PubMed   Mentions: 6  
    12. Tumour predisposition and cancer syndromes as models to study gene-environment interactions. Nat Rev Cancer. 2020 09; 20(9):533-549. Carbone M, Arron ST, Beutler B, Bononi A, Cavenee W, Cleaver JE, Croce CM, D'Andrea A, Foulkes WD, Gaudino G, Groden JL, Henske EP, Hickson ID, Hwang PM, Kolodner RD, Mak TW, Malkin D, Monnat RJ, Novelli F, Pass HI, Petrini JH, Schmidt LS, Yang H. PMID: 32472073; PMCID: PMC8104546.
      View in: PubMed   Mentions: 54     Fields:    Translation:HumansAnimals
    13. Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma. Proc Natl Acad Sci U S A. 2020 06 02; 117(22):12324-12331. Rajesh Y, Biswas A, Kumar U, Banerjee I, Das S, Maji S, Das SK, Emdad L, Cavenee WK, Mandal M, Fisher PB. PMID: 32409605; PMCID: PMC7275698.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    14. Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM. Mol Cancer Res. 2020 08; 18(8):1142-1152. Harachi M, Masui K, Honda H, Muragaki Y, Kawamata T, Cavenee WK, Mischel PS, Shibata N. PMID: 32366675.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    15. mTOR complex 2 is an integrator of cancer metabolism and epigenetics. Cancer Lett. 2020 05 28; 478:1-7. Masui K, Harachi M, Cavenee WK, Mischel PS, Shibata N. PMID: 32145344.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    16. MDA-9/Syntenin (SDCBP): Novel gene and therapeutic target for cancer metastasis. Pharmacol Res. 2020 05; 155:104695. Das SK, Maji S, Wechman SL, Bhoopathi P, Pradhan AK, Talukdar S, Sarkar D, Landry J, Guo C, Wang XY, Cavenee WK, Emdad L, Fisher PB. PMID: 32061839; PMCID: PMC7551653.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    17. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 Dec 09; 36(6):690-691. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 31821785; PMCID: PMC6946119.
      View in: PubMed   Mentions: 9     Fields:    
    18. mTORC2 links growth factor signaling with epigenetic regulation of iron metabolism in glioblastoma. J Biol Chem. 2019 12 20; 294(51):19740-19751. Masui K, Harachi M, Ikegami S, Yang H, Onizuka H, Yong WH, Cloughesy TF, Muragaki Y, Kawamata T, Arai N, Komori T, Cavenee WK, Mischel PS, Shibata N. PMID: 31712311; PMCID: PMC6926466.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    19. The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene. Genes (Basel). 2019 11 01; 10(11). Berry JL, Polski A, Cavenee WK, Dryja TP, Murphree AL, Gallie BL. PMID: 31683923; PMCID: PMC6895859.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    20. Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. Cell Metab. 2019 09 03; 30(3):525-538.e8. Bi J, Ichu TA, Zanca C, Yang H, Zhang W, Gu Y, Chowdhry S, Reed A, Ikegami S, Turner KM, Zhang W, Villa GR, Wu S, Quehenberger O, Yong WH, Kornblum HI, Rich JN, Cloughesy TF, Cavenee WK, Furnari FB, Cravatt BF, Mischel PS. PMID: 31303424; PMCID: PMC6742496.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    21. Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies. Cancer Gene Ther. 2020 05; 27(5):301-310. Staquicini FI, Smith TL, Tang FHF, Gelovani JG, Giordano RJ, Libutti SK, Sidman RL, Cavenee WK, Arap W, Pasqualini R. PMID: 31130731; PMCID: PMC6879804.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    22. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 May 13; 35(5):816. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 31085179; PMCID: PMC8717880.
      View in: PubMed   Mentions: 12     Fields:    
    23. Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope. Proc Natl Acad Sci U S A. 2019 05 14; 116(20):10009-10018. Orellana L, Thorne AH, Lema R, Gustavsson J, Parisian AD, Hospital A, Cordeiro TN, Bernadó P, Scott AM, Brun-Heath I, Lindahl E, Cavenee WK, Furnari FB, Orozco M. PMID: 31028138; PMCID: PMC6525488.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansCells
    24. Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review. JAMA Neurol. 2019 04 01; 76(4):492-500. Chohan MO, Marchiò S, Morrison LA, Sidman RL, Cavenee WK, Dejana E, Yonas H, Pasqualini R, Arap W. PMID: 30476961.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimals
    25. Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy. Proc Natl Acad Sci U S A. 2019 03 26; 116(13):6308-6312. Qu C, Wang Y, Wang P, Chen K, Wang M, Zeng H, Lu J, Song Q, Diplas BH, Tan D, Fan C, Guo Q, Zhu Z, Yin H, Jiang L, Chen X, Zhao H, He H, Wang Y, Li G, Bi X, Zhao X, Chen T, Tang H, Lv C, Wang D, Chen W, Zhou J, Zhao H, Cai J, Wang X, Wang S, Yan H, Zeng YX, Cavenee WK, Jiao Y. PMID: 30858324; PMCID: PMC6442629.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansCells
    26. MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF. Proc Natl Acad Sci U S A. 2019 03 19; 116(12):5687-5692. Pradhan AK, Bhoopathi P, Talukdar S, Scheunemann D, Sarkar D, Cavenee WK, Das SK, Emdad L, Fisher PB. PMID: 30842276; PMCID: PMC6431152.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansAnimalsCells
    27. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 03 18; 35(3):504-518.e7. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 30827889; PMCID: PMC6424615.
      View in: PubMed   Mentions: 65     Fields:    Translation:HumansAnimalsCells
    28. Rethinking Glioblastoma Therapy: MDA-9/Syntenin Targeted Small Molecule. ACS Chem Neurosci. 2019 03 20; 10(3):1121-1123. Das SK, Sarkar D, Cavenee WK, Emdad L, Fisher PB. PMID: 30681320.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    29. Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk. Cancer Res. 2019 03 15; 79(6):1239-1251. Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY. PMID: 30659021; PMCID: PMC6625517.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    30. Metabolic reprogramming in the pathogenesis of glioma: Update. Neuropathology. 2019 Feb; 39(1):3-13. Masui K, Onizuka H, Cavenee WK, Mischel PS, Shibata N. PMID: 30609184.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    31. Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine. Cell Death Differ. 2018 11; 25(11):1885-1904. Carbone M, Amelio I, Affar EB, Brugarolas J, Cannon-Albright LA, Cantley LC, Cavenee WK, Chen Z, Croce CM, Andrea A, Gandara D, Giorgi C, Jia W, Lan Q, Mak TW, Manley JL, Mikoshiba K, Onuchic JN, Pass HI, Pinton P, Prives C, Rothman N, Sebti SM, Turkson J, Wu X, Yang H, Yu H, Melino G. PMID: 30323273; PMCID: PMC6219489.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    32. Regulation of protective autophagy in anoikis-resistant glioma stem cells by SDCBP/MDA-9/Syntenin. Autophagy. 2018; 14(10):1845-1846. Talukdar S, Pradhan AK, Bhoopathi P, Shen XN, August LA, Windle JJ, Sarkar D, Furnari FB, Cavenee WK, Das SK, Emdad L, Fisher PB. PMID: 30118375; PMCID: PMC6135626.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    33. Reply to Yoshida: Delineating critical roles of MDA-9 in protective autophagy-mediated anoikis resistance in human glioma stem cells. Proc Natl Acad Sci U S A. 2018 08 14; 115(33):E7654-E7655. Talukdar S, Das SK, Emdad L, Sarkar D, Cavenee WK, Fisher PB. PMID: 30087190; PMCID: PMC6099876.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    34. Publisher Correction: PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. Nat Commun. 2018 05 25; 9:16217. Benitez JA, Ma J, D'Antonio M, Boyer A, Camargo MF, Zanca C, Kelly S, Khodadadi-Jamayran A, Jameson NM, Andersen M, Miletic H, Saberi S, Frazer KA, Cavenee WK, Furnari FB. PMID: 29799523; PMCID: PMC6026911.
      View in: PubMed   Mentions: 1     Fields:    
    35. MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proc Natl Acad Sci U S A. 2018 05 29; 115(22):5768-5773. Talukdar S, Pradhan AK, Bhoopathi P, Shen XN, August LA, Windle JJ, Sarkar D, Furnari FB, Cavenee WK, Das SK, Emdad L, Fisher PB. PMID: 29760085; PMCID: PMC5984507.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    36. Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts. J Vis Exp. 2018 04 26; (134). Benitez JA, Zanca C, Ma J, Cavenee WK, Furnari FB. PMID: 29757276; PMCID: PMC6100979.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    37. FHL2 interacts with EGFR to promote glioblastoma growth. Oncogene. 2018 03; 37(10):1386-1398. Sun L, Yu S, Xu H, Zheng Y, Lin J, Wu M, Wang J, Wang A, Lan Q, Furnari F, Cavenee W, Purow B, Li M. PMID: 29321665; PMCID: PMC8691187.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    38. Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme. Nat Commun. 2017 12 04; 8(1):1913. Newman JP, Wang GY, Arima K, Guan SP, Waters MR, Cavenee WK, Pan E, Aliwarga E, Chong ST, Kok CYL, Endaya BB, Habib AA, Horibe T, Ng WH, Ho IAW, Hui KM, Kordula T, Lam PYP. PMID: 29203859; PMCID: PMC5715073.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    39. Going viral? Linking the etiology of human prostate cancer to the PCA3 long noncoding RNA and oncogenic viruses. EMBO Mol Med. 2017 10; 9(10):1327-1330. Teixeira AA, Marchiò S, Dias-Neto E, Nunes DN, da Silva IT, Chackerian B, Barry M, Lauer RC, Giordano RJ, Sidman RL, Wheeler CM, Cavenee WK, Pasqualini R, Arap W. PMID: 28751581; PMCID: PMC5623838.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    40. Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE. Clin Cancer Res. 2018 02 15; 24(4):737-743. Alexander BM, Ba S, Berger MS, Berry DA, Cavenee WK, Chang SM, Cloughesy TF, Jiang T, Khasraw M, Li W, Mittman R, Poste GH, Wen PY, Yung WKA, Barker AD, GBM AGILE Network. PMID: 28814435.
      View in: PubMed   Mentions: 90     Fields:    Translation:Humans
    41. Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity. Genes Dev. 2017 06 15; 31(12):1212-1227. Zanca C, Villa GR, Benitez JA, Thorne AH, Koga T, D'Antonio M, Ikegami S, Ma J, Boyer AD, Banisadr A, Jameson NM, Parisian AD, Eliseeva OV, Barnabe GF, Liu F, Wu S, Yang H, Wykosky J, Frazer KA, Verkhusha VV, Isaguliants MG, Weiss WA, Gahman TC, Shiau AK, Chen CC, Mischel PS, Cavenee WK, Furnari FB. PMID: 28724615; PMCID: PMC5558924.
      View in: PubMed   Mentions: 41     Fields:    Translation:HumansAnimalsCells
    42. Selective replication of oncolytic virus M1 results in a bystander killing effect that is potentiated by Smac mimetics. Proc Natl Acad Sci U S A. 2017 06 27; 114(26):6812-6817. Cai J, Lin Y, Zhang H, Liang J, Tan Y, Cavenee WK, Yan G. PMID: 28607091; PMCID: PMC5495246.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    43. PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. Nat Commun. 2017 05 12; 8:15223. Benitez JA, Ma J, D'Antonio M, Boyer A, Camargo MF, Zanca C, Kelly S, Khodadadi-Jamayran A, Jameson NM, Andersen M, Miletic H, Saberi S, Frazer KA, Cavenee WK, Furnari FB. PMID: 28497778; PMCID: PMC5437297.
      View in: PubMed   Mentions: 69     Fields:    Translation:HumansAnimalsCells
    44. Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling. NPJ Precis Oncol. 2017; 1(1):1. Liu F, Mischel PS, Cavenee WK. PMID: 29872691; PMCID: PMC5871882.
      View in: PubMed   Mentions: 2  
    45. Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. Nature. 2017 03 02; 543(7643):122-125. Turner KM, Deshpande V, Beyter D, Koga T, Rusert J, Lee C, Li B, Arden K, Ren B, Nathanson DA, Kornblum HI, Taylor MD, Kaushal S, Cavenee WK, Wechsler-Reya R, Furnari FB, Vandenberg SR, Rao PN, Wahl GM, Bafna V, Mischel PS. PMID: 28178237; PMCID: PMC5334176.
      View in: PubMed   Mentions: 339     Fields:    Translation:HumansCells
    46. Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin. Proc Natl Acad Sci U S A. 2017 01 10; 114(2):370-375. Kegelman TP, Wu B, Das SK, Talukdar S, Beckta JM, Hu B, Emdad L, Valerie K, Sarkar D, Furnari FB, Cavenee WK, Wei J, Purves A, De SK, Pellecchia M, Fisher PB. PMID: 28011764; PMCID: PMC5240699.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansAnimalsCells
    47. Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme. J Control Release. 2016 12 28; 244(Pt A):14-23. Chou ST, Patil R, Galstyan A, Gangalum PR, Cavenee WK, Furnari FB, Ljubimov VA, Chesnokova A, Kramerov AA, Ding H, Falahatian V, Mashouf L, Fox I, Black KL, Holler E, Ljubimov AV, Ljubimova JY. PMID: 27825958; PMCID: PMC5308909.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    48. An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers. Cancer Cell. 2016 Nov 14; 30(5):683-693. Villa GR, Hulce JJ, Zanca C, Bi J, Ikegami S, Cahill GL, Gu Y, Lum KM, Masui K, Yang H, Rong X, Hong C, Turner KM, Liu F, Hon GC, Jenkins D, Martini M, Armando AM, Quehenberger O, Cloughesy TF, Furnari FB, Cavenee WK, Tontonoz P, Gahman TC, Shiau AK, Cravatt BF, Mischel PS. PMID: 27746144; PMCID: PMC5479636.
      View in: PubMed   Mentions: 164     Fields:    Translation:HumansAnimalsCells
    49. mTORC2 activity in brain cancer: Extracellular nutrients are required to maintain oncogenic signaling. Bioessays. 2016 09; 38(9):839-44. Masui K, Shibata N, Cavenee WK, Mischel PS. PMID: 27427440; PMCID: PMC5501721.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    50. Cancer metabolism as a central driving force of glioma pathogenesis. Brain Tumor Pathol. 2016 Jul; 33(3):161-8. Masui K, Cavenee WK, Mischel PS. PMID: 27295313; PMCID: PMC5488809.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    51. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016 06; 131(6):803-20. Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW. PMID: 27157931.
      View in: PubMed   Mentions: 6823     Fields:    Translation:HumansAnimals
    52. Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma. Cancer Cell. 2016 Apr 11; 29(4):563-573. Wei W, Shin YS, Xue M, Matsutani T, Masui K, Yang H, Ikegami S, Gu Y, Herrmann K, Johnson D, Ding X, Hwang K, Kim J, Zhou J, Su Y, Li X, Bonetti B, Chopra R, James CD, Cavenee WK, Cloughesy TF, Mischel PS, Heath JR, Gini B. PMID: 27070703; PMCID: PMC4831071.
      View in: PubMed   Mentions: 80     Fields:    Translation:HumansAnimalsCells
    53. mTORC2 and Metabolic Reprogramming in GBM: at the Interface of Genetics and Environment. Brain Pathol. 2015 Nov; 25(6):755-9. Masui K, Cavenee WK, Mischel PS. PMID: 26526943; PMCID: PMC4636016.
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    111. Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. Cancer Cell. 2008 Apr; 13(4):355-64. Wiedemeyer R, Brennan C, Heffernan TP, Xiao Y, Mahoney J, Protopopov A, Zheng H, Bignell G, Furnari F, Cavenee WK, Hahn WC, Ichimura K, Collins VP, Chu GC, Stratton MR, Ligon KL, Futreal PA, Chin L. PMID: 18394558; PMCID: PMC2292238.
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    112. Guilt by association: PAX3-FOXO1 regulates gene expression through selective destabilization of the EGR1 transcription factor. Cell Cycle. 2008 Apr 01; 7(7):837-41. Roeb W, Boyer A, Cavenee WK, Arden KC. PMID: 18414034.
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    113. Development of a real-time RT-PCR assay for detecting EGFRvIII in glioblastoma samples. Clin Cancer Res. 2008 Jan 15; 14(2):488-93. Yoshimoto K, Dang J, Zhu S, Nathanson D, Huang T, Dumont R, Seligson DB, Yong WH, Xiong Z, Rao N, Winther H, Chakravarti A, Bigner DD, Mellinghoff IK, Horvath S, Cavenee WK, Cloughesy TF, Mischel PS. PMID: 18223223.
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    114. Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organs. Genome Res. 2008 Jan; 18(1):46-59. Barrera LO, Li Z, Smith AD, Arden KC, Cavenee WK, Zhang MQ, Green RD, Ren B. PMID: 18042645; PMCID: PMC2134779.
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    115. PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1. Proc Natl Acad Sci U S A. 2007 Nov 13; 104(46):18085-90. Roeb W, Boyer A, Cavenee WK, Arden KC. PMID: 17986608; PMCID: PMC2084300.
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    116. Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev. 2007 Nov 01; 21(21):2683-710. Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. PMID: 17974913.
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    117. Uncovering therapeutic targets for glioblastoma: a systems biology approach. Cell Cycle. 2007 Nov 15; 6(22):2750-4. Huang PH, Cavenee WK, Furnari FB, White FM. PMID: 17986864.
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    118. Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12867-72. Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM. PMID: 17646646; PMCID: PMC1937558.
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    119. The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol. 2007 Aug; 114(2):97-109. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. PMID: 17618441; PMCID: PMC1929165.
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    120. The efficacy of epidermal growth factor receptor-specific antibodies against glioma xenografts is influenced by receptor levels, activation status, and heterodimerization. Clin Cancer Res. 2007 Mar 15; 13(6):1911-25. Johns TG, Perera RM, Vernes SC, Vitali AA, Cao DX, Cavenee WK, Scott AM, Furnari FB. PMID: 17363548.
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    121. Synergistic cytotoxicity through the activation of multiple apoptosis pathways in human glioma cells induced by combined treatment with ionizing radiation and tumor necrosis factor-related apoptosis-inducing ligand. J Neurosurg. 2007 Mar; 106(3):407-16. Nagane M, Cavenee WK, Shiokawa Y. PMID: 17367063.
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    122. Therapeutic anti-EGFR antibody 806 generates responses in murine de novo EGFR mutant-dependent lung carcinomas. J Clin Invest. 2007 Feb; 117(2):346-52. Li D, Ji H, Zaghlul S, McNamara K, Liang MC, Shimamura T, Kubo S, Takahashi M, Chirieac LR, Padera RF, Scott AM, Jungbluth AA, Cavenee WK, Old LJ, Demetri GD, Wong KK. PMID: 17256054; PMCID: PMC1770949.
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    123. Transgenic mice expressing PAX3-FKHR have multiple defects in muscle development, including ectopic skeletal myogenesis in the developing neural tube. Transgenic Res. 2006 Oct; 15(5):595-614. Finckenstein FG, Davicioni E, Osborn KG, Cavenee WK, Arden KC, Anderson MJ. PMID: 16952014.
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    124. Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells. Cancer Res. 2006 Aug 15; 66(16):7864-9. Wang MY, Lu KV, Zhu S, Dia EQ, Vivanco I, Shackleford GM, Cavenee WK, Mellinghoff IK, Cloughesy TF, Sawyers CL, Mischel PS. PMID: 16912159.
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    125. PCAF modulates PTEN activity. J Biol Chem. 2006 Sep 08; 281(36):26562-8. Okumura K, Mendoza M, Bachoo RM, DePinho RA, Cavenee WK, Furnari FB. PMID: 16829519.
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    126. The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell. 2006 May; 9(5):379-90. Carrasco DR, Fenton T, Sukhdeo K, Protopopova M, Enos M, You MJ, Di Vizio D, Divicio D, Nogueira C, Stommel J, Pinkus GS, Fletcher C, Hornick JL, Cavenee WK, Furnari FB, Depinho RA. PMID: 16697958.
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    127. Identification of EGFRvIII-derived CTL epitopes restricted by HLA A0201 for dendritic cell based immunotherapy of gliomas. J Neurooncol. 2006 Jan; 76(1):23-30. Wu AH, Xiao J, Anker L, Hall WA, Gregerson DS, Cavenee WK, Chen W, Low WC. PMID: 16155724.
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    128. Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. N Engl J Med. 2005 Nov 10; 353(19):2012-24. Mellinghoff IK, Wang MY, Vivanco I, Haas-Kogan DA, Zhu S, Dia EQ, Lu KV, Yoshimoto K, Huang JH, Chute DJ, Riggs BL, Horvath S, Liau LM, Cavenee WK, Rao PN, Beroukhim R, Peck TC, Lee JC, Sellers WR, Stokoe D, Prados M, Cloughesy TF, Sawyers CL, Mischel PS. PMID: 16282176.
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    129. Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity. Clin Cancer Res. 2005 Sep 01; 11(17):6390-9. Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. PMID: 16144944.
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    130. PTEN: a novel anti-oncogenic function independent of phosphatase activity. Cell Cycle. 2005 Apr; 4(4):540-2. Okumura K, Zhao M, DePinho RA, Furnari FB, Cavenee WK. PMID: 15753657.
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    131. Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2703-6. Okumura K, Zhao M, Depinho RA, Furnari FB, Cavenee WK. PMID: 15659546; PMCID: PMC549467.
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    132. Combination therapy of inhibitors of epidermal growth factor receptor/vascular endothelial growth factor receptor 2 (AEE788) and the mammalian target of rapamycin (RAD001) offers improved glioblastoma tumor growth inhibition. Mol Cancer Ther. 2005 Jan; 4(1):101-12. Goudar RK, Shi Q, Hjelmeland MD, Keir ST, McLendon RE, Wikstrand CJ, Reese ED, Conrad CA, Traxler P, Lane HA, Reardon DA, Cavenee WK, Wang XF, Bigner DD, Friedman HS, Rich JN. PMID: 15657358.
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    133. Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. Mol Cell Biol. 2004 10; 24(20):8981-93. Schmidt MHH, Hoeller D, Yu J, Furnari FB, Cavenee WK, Dikic I, Bögler O. PMID: 15456872; PMCID: PMC517880.
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    134. Methylation Profiling Identifies Epigenetic Markers for High-grade Gliomas. Cancer Genomics Proteomics. 2004 May-Jun; 1(3):209-214. Waha A, Rodrigues FJ, Waha A, Meyer-Puttlitz B, Cavenee WK, Huang TH, Wiestler OD, Yan PS. PMID: 31394655.
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    135. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc Natl Acad Sci U S A. 2004 Mar 02; 101(9):2975-80. Hosaka T, Biggs WH, Tieu D, Boyer AD, Varki NM, Cavenee WK, Arden KC. PMID: 14978268; PMCID: PMC365730.
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    136. Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma. Brain Tumor Pathol. 2004; 21(2):53-6. Nishikawa R, Sugiyama T, Narita Y, Furnari F, Cavenee WK, Matsutani M. PMID: 15700833.
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    137. The recessive nature of dominance. Genes Chromosomes Cancer. 2003 Dec; 38(4):322-5. Cavenee WK. PMID: 14566850.
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    138. The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13418-23. Brentani H, Caballero OL, Camargo AA, da Silva AM, da Silva WA, Dias Neto E, Grivet M, Gruber A, Guimaraes PE, Hide W, Iseli C, Jongeneel CV, Kelso J, Nagai MA, Ojopi EP, Osorio EC, Reis EM, Riggins GJ, Simpson AJ, de Souza S, Stevenson BJ, Strausberg RL, Tajara EH, Verjovski-Almeida S, Acencio ML, Bengtson MH, Bettoni F, Bodmer WF, Briones MR, Camargo LP, Cavenee W, Cerutti JM, Coelho Andrade LE, Costa dos Santos PC, Ramos Costa MC, da Silva IT, Estécio MR, Sa Ferreira K, Furnari FB, Faria M, Galante PA, Guimaraes GS, Holanda AJ, Kimura ET, Leerkes MR, Lu X, Maciel RM, Martins EA, Massirer KB, Melo AS, Mestriner CA, Miracca EC, Miranda LL, Nobrega FG, Oliveira PS, Paquola AC, Pandolfi JR, Campos Pardini MI, Passetti F, Quackenbush J, Schnabel B, Sogayar MC, Souza JE, Valentini SR, Zaiats AC, Amaral EJ, Arnaldi LA, de Araújo AG, de Bessa SA, Bicknell DC, Ribeiro de Camaro ME, Carraro DM, Carrer H, Carvalho AF, Colin C, Costa F, Curcio C, Guerreiro da Silva ID, Pereira da Silva N, Dellamano M, El-Dorry H, Espreafico EM, Scattone Ferreira AJ, Ayres Ferreira C, Fortes MA, Gama AH, Giannella-Neto D, Giannella ML, Giorgi RR, Goldman GH, Goldman MH, Hackel C, Ho PL, Kimura EM, Kowalski LP, Krieger JE, Leite LC, Lopes A, Luna AM, Mackay A, Mari SK, Marques AA, Martins WK, Montagnini A, Mourão Neto M, Nascimento AL, Neville AM, Nobrega MP, O'Hare MJ, Otsuka AY, Ruas de Melo AI, Paco-Larson ML, Guimarães Pereira G, Pereira da Silva N, Pesquero JB, Pessoa JG, Rahal P, Rainho CA, Rodrigues V, Rogatto SR, Romano CM, Romeiro JG, Rossi BM, Rusticci M, Guerra de Sá R, Sant' Anna SC, Sarmazo ML, Silva TC, Soares FA, Sonati Mde F, de Freitas Sousa J, Queiroz D, Valente V, Vettore AL, Villanova FE, Zago MA, Zalcberg H, Human Cancer Genome Project/Cancer Genome Anatomy Project Annotation Consortium, Human Cancer Genome Project Sequencing Consortium. PMID: 14593198; PMCID: PMC263829.
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    139. Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2. Proc Natl Acad Sci U S A. 2003 Jul 22; 100(15):8904-9. Hu B, Guo P, Fang Q, Tao HQ, Wang D, Nagane M, Huang HJ, Gunji Y, Nishikawa R, Alitalo K, Cavenee WK, Cheng SY. PMID: 12861074; PMCID: PMC166411.
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    140. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci U S A. 2003 Jul 08; 100(14):8164-9. Li Z, Van Calcar S, Qu C, Cavenee WK, Zhang MQ, Ren B. PMID: 12808131; PMCID: PMC166200.
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    141. Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization. Proc Natl Acad Sci U S A. 2003 05 27; 100(11):6505-10. Schmidt MHH, Furnari FB, Cavenee WK, Bögler O. PMID: 12734385; PMCID: PMC164476.
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    142. Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am J Pathol. 2003 Apr; 162(4):1083-93. Guo P, Hu B, Gu W, Xu L, Wang D, Huang HJ, Cavenee WK, Cheng SY. PMID: 12651601; PMCID: PMC1851242.
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    143. Preparing for serendipity. Cancer Biol Ther. 2003 Mar-Apr; 2(2):213-5. Cavenee WK. PMID: 12750567.
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    144. A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor. Proc Natl Acad Sci U S A. 2003 Jan 21; 100(2):639-44. Jungbluth AA, Stockert E, Huang HJ, Collins VP, Coplan K, Iversen K, Kolb D, Johns TJ, Scott AM, Gullick WJ, Ritter G, Cohen L, Scanlan MJ, Cavenee WK, Old LJ, Cavanee WK. PMID: 12515857; PMCID: PMC141049.
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    145. Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas. Cancer Res. 2002 Nov 15; 62(22):6764-9. Narita Y, Nagane M, Mishima K, Huang HJ, Furnari FB, Cavenee WK. PMID: 12438278.
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    146. Muscling in on rhabdomyosarcoma. Nat Med. 2002 Nov; 8(11):1200-1. Cavenee WK. PMID: 12411939.
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    147. Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1. Nat Genet. 2002 Oct; 32(2):245-53. Nakae J, Biggs WH, Kitamura T, Cavenee WK, Wright CV, Arden KC, Accili D. PMID: 12219087.
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    148. Genetics and new approaches to cancer therapy. Carcinogenesis. 2002 May; 23(5):683-6. Cavenee WK. PMID: 12016138.
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    149. A novel seven transmembrane receptor induced during the early steps of astrocyte differentiation identified by differential expression. J Neurochem. 2002 May; 81(3):575-88. De Smet C, Nishimori H, Furnari FB, Bögler O, Huang HJ, Cavenee WK. PMID: 12065666.
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    150. Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene. Int J Cancer. 2002 Mar 20; 98(3):398-408. Johns TG, Stockert E, Ritter G, Jungbluth AA, Huang HJ, Cavenee WK, Smyth FE, Hall CM, Watson N, Nice EC, Gullick WJ, Old LJ, Burgess AW, Scott AM. PMID: 11920591.
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    151. The WHO classification of tumors of the nervous system. J Neuropathol Exp Neurol. 2002 Mar; 61(3):215-25; discussion 226-9. Kleihues P, Louis DN, Scheithauer BW, Rorke LB, Reifenberger G, Burger PC, Cavenee WK. PMID: 11895036.
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    152. Restriction landmark genome scanning. Methods Mol Biol. 2002; 200:53-70. Costello JF, Plass C, Cavenee WK. PMID: 11951655.
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    153. CD95-mediated apoptosis of human glioma cells: modulation by epidermal growth factor receptor activity. Brain Pathol. 2002 Jan; 12(1):12-20. Steinbach JP, Supra P, Huang HJ, Cavenee WK, Weller M. PMID: 11770895; PMCID: PMC8095827.
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    154. The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor. J Biol Chem. 2001 Dec 07; 276(49):46313-8. Klingler-Hoffmann M, Fodero-Tavoletti MT, Mishima K, Narita Y, Cavenee WK, Furnari FB, Huang HJ, Tiganis T. PMID: 11514572.
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    155. Vascular endothelial growth factor isoforms display distinct activities in promoting tumor angiogenesis at different anatomic sites. Cancer Res. 2001 Dec 01; 61(23):8569-77. Guo P, Xu L, Pan S, Brekken RA, Yang ST, Whitaker GB, Nagane M, Thorpe PE, Rosenbaum JS, Su Huang HJ, Cavenee WK, Cheng SY. PMID: 11731444.
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    156. Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor. J Neurosurg. 2001 Sep; 95(3):472-9. Nagane M, Narita Y, Mishima K, Levitzki A, Burgess AW, Cavenee WK, Huang HJ. PMID: 11565870.
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    157. Trypanosoma cruzi trans-sialidase: a potent and specific survival factor for human Schwann cells by means of phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9936-41. Chuenkova MV, Furnari FB, Cavenee WK, Pereira MA. PMID: 11481434; PMCID: PMC55556.
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    158. Monoclonal antibody 806 inhibits the growth of tumor xenografts expressing either the de2-7 or amplified epidermal growth factor receptor (EGFR) but not wild-type EGFR. Cancer Res. 2001 Jul 15; 61(14):5355-61. Luwor RB, Johns TG, Murone C, Huang HJ, Cavenee WK, Ritter G, Old LJ, Burgess AW, Scott AM. PMID: 11454674.
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    159. Growth suppression of intracranial xenografted glioblastomas overexpressing mutant epidermal growth factor receptors by systemic administration of monoclonal antibody (mAb) 806, a novel monoclonal antibody directed to the receptor. Cancer Res. 2001 Jul 15; 61(14):5349-54. Mishima K, Johns TG, Luwor RB, Scott AM, Stockert E, Jungbluth AA, Ji XD, Suvarna P, Voland JR, Old LJ, Huang HJ, Cavenee WK. PMID: 11454673.
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    160. Malignant glioma: genetics and biology of a grave matter. Genes Dev. 2001 Jun 01; 15(11):1311-33. Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA. PMID: 11390353.
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    161. The potential of TRAIL for cancer chemotherapy. Apoptosis. 2001 Jun; 6(3):191-7. Nagane M, Huang HJ, Cavenee WK. PMID: 11388668.
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    162. Identification and characterization of members of the FKHR (FOX O) subclass of winged-helix transcription factors in the mouse. Mamm Genome. 2001 Jun; 12(6):416-25. Biggs WH, Cavenee WK, Arden KC. PMID: 11353388.
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    163. Non-isotopic silver-stained SSCP is more sensitive than automated direct sequencing for the detection of PTEN mutations in a mixture of DNA extracted from normal and tumor cells. Int J Oncol. 2001 May; 18(5):1023-6. Fan X, Furnari FB, Cavenee WK, Castresana JS. PMID: 11295051.
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    164. Embryonic expression of the tumor-associated PAX3-FKHR fusion protein interferes with the developmental functions of Pax3. Proc Natl Acad Sci U S A. 2001 Feb 13; 98(4):1589-94. Anderson MJ, Shelton GD, Cavenee WK, Arden KC. PMID: 11171995; PMCID: PMC29301.
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    165. Is annexin 7 a tumor suppressor gene in prostate cancer? Pharmacogenomics J. 2001; 1(2):92-4. Cardó-Vila M, Arden KC, Cavenee WK, Pasqualini R, Arap W. PMID: 11911446.
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    166. Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications. Cancer Lett. 2001 Jan; 162 Suppl:S17-S21. Nagane M, Lin H, Cavenee WK, Huang HJ. PMID: 11164186.
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    167. A peptide derived from the non-receptor-binding region of urokinase plasminogen activator inhibits glioblastoma growth and angiogenesis in vivo in combination with cisplatin. Proc Natl Acad Sci U S A. 2000 Jul 18; 97(15):8484-9. Mishima K, Mazar AP, Gown A, Skelly M, Ji XD, Wang XD, Jones TR, Cavenee WK, Huang HJ. PMID: 10890917; PMCID: PMC26974.
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    168. High-grade gliomas with chromosome 1p loss. J Neurosurg. 2000 Jun; 92(6):1080-1. Cavenee WK. PMID: 10839286.
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    169. IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation. Oncogene. 2000 May 18; 19(22):2687-94. Reiss K, Wang JY, Romano G, Furnari FB, Cavenee WK, Morrione A, Tu X, Baserga R. PMID: 10851068.
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    170. Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP. Genomics. 2000 Mar 01; 64(2):195-202. Amler LC, Bauer A, Corvi R, Dihlmann S, Praml C, Cavenee WK, Schwab M, Hampton GM. PMID: 10729226.
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    171. Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor-related apoptosis-inducing ligand in vitro and in vivo. Cancer Res. 2000 Feb 15; 60(4):847-53. Nagane M, Pan G, Weddle JJ, Dixit VM, Cavenee WK, Huang HJ. PMID: 10706092.
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    172. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet. 2000 Feb; 24(2):132-8. Costello JF, Frühwald MC, Smiraglia DJ, Rush LJ, Robertson GP, Gao X, Wright FA, Feramisco JD, Peltomäki P, Lang JC, Schuller DE, Yu L, Bloomfield CD, Caligiuri MA, Yates A, Nishikawa R, Su Huang H, Petrelli NJ, Zhang X, O'Dorisio MS, Held WA, Cavenee WK, Plass C. PMID: 10655057.
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    173. SETA: a novel SH3 domain-containing adapter molecule associated with malignancy in astrocytes. Neuro Oncol. 2000 01; 2(1):6-15. Bögler O, Furnari FB, Kindler-Roehrborn A, Sykes VW, Yung R, Huang HJ, Cavenee WK. PMID: 11302255; PMCID: PMC1920697.
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    174. Aberrant methylation of genes in low-grade astrocytomas. Brain Tumor Pathol. 2000; 17(2):49-56. Costello JF, Plass C, Cavenee WK. PMID: 11210171.
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    175. Analysis of the p300/CBP-Associated Factor (PCAF) gene in astrocytic tumors. J Neurooncol. 2000; 46(1):17-22. Nishimori H, Nishikawa R, Fujimaki T, Nakagomi T, Matsutani M, Huang HJ, Cavenee WK. PMID: 10896202.
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    176. Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis. Cancer Res. 1999 Nov 01; 59(21):5608-14. Valter MM, Hügel A, Huang HJ, Cavenee WK, Wiestler OD, Pietsch T, Wernert N. PMID: 10554042.
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    177. The retinoblastoma tumor suppressor inhibits cellular proliferation through two distinct mechanisms: inhibition of cell cycle progression and induction of cell death. Oncogene. 1999 Sep 16; 18(37):5239-45. Knudsen KE, Weber E, Arden KC, Cavenee WK, Feramisco JR, Knudsen ES. PMID: 10498874.
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    178. The chromosome 10 monosomy common in human melanomas results from loss of two separate tumor suppressor loci. Cancer Res. 1999 Aug 01; 59(15):3596-601. Robertson GP, Herbst RA, Nagane M, Huang HJ, Cavenee WK. PMID: 10446968.
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    179. PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis. Oncogene. 1999 Jul 08; 18(27):3936-43. Wick W, Furnari FB, Naumann U, Cavenee WK, Weller M. PMID: 10435616.
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    180. Identification and validation of tumor suppressor genes. Mol Cell Biol Res Commun. 1999 Jul; 2(1):1-10. Robertson GP, Huang HJ, Cavenee WK. PMID: 10527883.
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    181. Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc Natl Acad Sci U S A. 1999 Jun 22; 96(13):7421-6. Biggs WH, Meisenhelder J, Hunter T, Cavenee WK, Arden KC. PMID: 10377430; PMCID: PMC22101.
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    182. A new tool for the rapid cloning of amplified and hypermethylated human DNA sequences from restriction landmark genome scanning gels. Genomics. 1999 Jun 15; 58(3):254-62. Smiraglia DJ, Frühwald MC, Costello JF, McCormick SP, Dai Z, Peltomäki P, O'Dorisio MS, Cavenee WK, Plass C. PMID: 10373323.
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    183. D-type cyclins complex with the androgen receptor and inhibit its transcriptional transactivation ability. Cancer Res. 1999 May 15; 59(10):2297-301. Knudsen KE, Cavenee WK, Arden KC. PMID: 10344732.
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    184. Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. Cancer Res. 1999 Apr 01; 59(7):1464-72. Wang D, Huang HJ, Kazlauskas A, Cavenee WK. PMID: 10197615.
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    185. Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers. Cancer Res. 1999 Feb 15; 59(4):798-802. Bachman KE, Herman JG, Corn PG, Merlo A, Costello JF, Cavenee WK, Baylin SB, Graff JR. PMID: 10029065.
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    186. Malignant transformation of p53-deficient astrocytes is modulated by environmental cues in vitro. Cell Growth Differ. 1999 Feb; 10(2):73-86. Bögler O, Nagane M, Gillis J, Huang HJ, Cavenee WK. PMID: 10074901.
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    187. Causes of drug resistance and novel therapeutic opportunities for the treatment of glioblastoma. Drug Resist Updat. 1999 Feb; 2(1):30-37. Nagane M, Huang HJ, Cavenee WK. PMID: 11504467.
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    188. The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells. Cancer Res. 1998 Nov 15; 58(22):5002-8. Furnari FB, Huang HJ, Cavenee WK. PMID: 9823298.
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    189. Expression of vascular endothelial growth factor in human brain tumors. Acta Neuropathol. 1998 Nov; 96(5):453-62. Nishikawa R, Cheng SY, Nagashima R, Huang HJ, Cavenee WK, Matsutani M. PMID: 9829808.
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    190. Host microvasculature influence on tumor vascular morphology and endothelial gene expression. Am J Pathol. 1998 Oct; 153(4):1239-48. Roberts WG, Delaat J, Nagane M, Huang S, Cavenee WK, Palade GE. PMID: 9777955; PMCID: PMC1853053.
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    191. Multiple G1 regulatory elements control the androgen-dependent proliferation of prostatic carcinoma cells. J Biol Chem. 1998 Aug 07; 273(32):20213-22. Knudsen KE, Arden KC, Cavenee WK. PMID: 9685369.
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    192. In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9418-23. Robertson GP, Furnari FB, Miele ME, Glendening MJ, Welch DR, Fountain JW, Lugo TG, Huang HJ, Cavenee WK. PMID: 9689095; PMCID: PMC21353.
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    193. Absence of PTEN/MMAC1 germ-line mutations in sporadic Bannayan-Riley-Ruvalcaba syndrome. Cancer Res. 1998 Jul 01; 58(13):2724-6. Carethers JM, Furnari FB, Zigman AF, Lavine JE, Jones MC, Graham GE, Teebi AS, Huang HJ, Ha HT, Chauhan DP, Chang CL, Cavenee WK, Boland CR. PMID: 9661881.
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    194. Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases. Proc Natl Acad Sci U S A. 1998 May 12; 95(10):5724-9. Nagane M, Levitzki A, Gazit A, Cavenee WK, Huang HJ. PMID: 9576951; PMCID: PMC20446.
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    195. Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily. Genomics. 1998 Jan 15; 47(2):187-99. Anderson MJ, Viars CS, Czekay S, Cavenee WK, Arden KC. PMID: 9479491.
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    196. Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc Natl Acad Sci U S A. 1997 Nov 11; 94(23):12479-84. Furnari FB, Lin H, Huang HS, Cavenee WK. PMID: 9356475; PMCID: PMC25009.
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    197. Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189. Proc Natl Acad Sci U S A. 1997 Oct 28; 94(22):12081-7. Cheng SY, Nagane M, Huang HS, Cavenee WK. PMID: 9342366; PMCID: PMC23709.
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    198. Functional analysis of wild-type and malignant glioma derived CDKN2Abeta alleles: evidence for an RB-independent growth suppressive pathway. Oncogene. 1997 Oct 23; 15(17):2013-20. Arap W, Knudsen E, Sewell DA, Sidransky D, Wang JY, Huang HJ, Cavenee WK. PMID: 9366518.
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    199. Genetic alterations accumulate during cervical tumorigenesis and indicate a common origin for multifocal lesions. Cancer Res. 1997 Oct 01; 57(19):4171-6. Larson AA, Liao SY, Stanbridge EJ, Cavenee WK, Hampton GM. PMID: 9331069.
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    200. High resolution analysis of chromosome 3p alterations in cervical carcinoma. Cancer Res. 1997 Sep 15; 57(18):4082-90. Larson AA, Kern S, Curtiss S, Gordon R, Cavenee WK, Hampton GM. PMID: 9307297.
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    201. An arrayed human not I-EcoRV boundary library as a tool for RLGS spot analysis. DNA Res. 1997 Jun 30; 4(3):253-5. Plass C, Weichenhan D, Catanese J, Costello JF, Yu F, Yu L, Smiraglia D, Cavenee WK, Caligiuri MA, deJong P, Held WA. PMID: 9330914.
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    202. Further evidence for ultraviolet light induction of CDKN2 (p16INK4) mutations in sporadic melanoma in vivo. J Invest Dermatol. 1997 Jun; 108(6):950. Herbst RA, Gutzmer R, Matiaske F, Mommert S, Kapp A, Weiss J, Arden KC, Cavenee WK. PMID: 9182829.
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    203. Advances in the molecular genetics of gliomas. Curr Opin Oncol. 1997 May; 9(3):215-22. Nagane M, Huang HJ, Cavenee WK. PMID: 9229142.
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    204. The expression of RET and its multiple splice forms in developing human kidney. Oncogene. 1997 Apr 17; 14(15):1811-8. Ivanchuk SM, Eng C, Cavenee WK, Mulligan LM. PMID: 9150387.
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    205. Cyclin-dependent kinase 6 (CDK6) amplification in human gliomas identified using two-dimensional separation of genomic DNA. Cancer Res. 1997 Apr 01; 57(7):1250-4. Costello JF, Plass C, Arap W, Chapman VM, Held WA, Berger MS, Su Huang HJ, Cavenee WK. PMID: 9102208.
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    206. Point mutations can inactivate in vitro and in vivo activities of p16(INK4a)/CDKN2A in human glioma. Oncogene. 1997 Feb 06; 14(5):603-9. Arap W, Knudsen ES, Wang JY, Cavenee WK, Huang HJ. PMID: 9053859.
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    207. Expression and distribution of vascular endothelial growth factor protein in human brain tumors. Acta Neuropathol. 1997 Feb; 93(2):109-17. Pietsch T, Valter MM, Wolf HK, von Deimling A, Huang HJ, Cavenee WK, Wiestler OD. PMID: 9039457.
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    208. The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol Chem. 1997 Jan 31; 272(5):2927-35. Huang HS, Nagane M, Klingbeil CK, Lin H, Nishikawa R, Ji XD, Huang CM, Gill GN, Wiley HS, Cavenee WK. PMID: 9006938.
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    209. Population variation at the polymorphic ApaLI restriction enzyme site in intron 5 of the WT1 gene. Clin Genet. 1996 Dec; 50(6):555-7. Besnard-Guérin C, Winqvist R, Newsham I, Cavenee WK. PMID: 9147899.
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    210. A common mutant epidermal growth factor receptor confers enhanced tumorigenicity on human glioblastoma cells by increasing proliferation and reducing apoptosis. Cancer Res. 1996 Nov 01; 56(21):5079-86. Nagane M, Coufal F, Lin H, Bögler O, Cavenee WK, Huang HJ. PMID: 8895767.
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    211. Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway. J Biol Chem. 1996 Oct 11; 271(41):25639-45. Prigent SA, Nagane M, Lin H, Huvar I, Boss GR, Feramisco JR, Cavenee WK, Huang HS. PMID: 8810340.
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    212. Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors. Cancer Res. 1996 Sep 01; 56(17):3859-61. Han Y, Caday CG, Nanda A, Cavenee WK, Huang HJ. PMID: 8752145.
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    213. cAMP effects on myogenic gene expression in rhabdomyosarcoma cells. Exp Cell Res. 1996 Aug 25; 227(1):55-62. Wasserman LM, Newsham I, Huang HJ, Cavenee WK. PMID: 8806451.
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    214. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8502-7. Cheng SY, Huang HJ, Nagane M, Ji XD, Wang D, Shih CC, Arap W, Huang CM, Cavenee WK. PMID: 8710899; PMCID: PMC38701.
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    215. Report of the Ninth International Symposium of the Foundation for Promotion of Cancer Research: basic and clinical research in brain tumors. Jpn J Clin Oncol. 1996 Aug; 26(4):277-82. Black PM, Nomura K, Cavenee WK, Kakizoe T, Mukai K. PMID: 8765189.
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    216. Detection of the t(2;13) chromosomal translocation in alveolar rhabdomyosarcoma using the reverse transcriptase-polymerase chain reaction. Genes Chromosomes Cancer. 1996 Aug; 16(4):254-60. Arden KC, Anderson MJ, Finckenstein FG, Czekay S, Cavenee WK. PMID: 8875239.
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    217. Simultaneous assessment of loss of heterozygosity at multiple microsatellite loci using semi-automated fluorescence-based detection: subregional mapping of chromosome 4 in cervical carcinoma. Proc Natl Acad Sci U S A. 1996 Jun 25; 93(13):6704-9. Hampton GM, Larson AA, Baergen RN, Sommers RL, Kern S, Cavenee WK. PMID: 8692882; PMCID: PMC39090.
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    218. Silencing of p16/CDKN2 expression in human gliomas by methylation and chromatin condensation. Cancer Res. 1996 May 15; 56(10):2405-10. Costello JF, Berger MS, Huang HS, Cavenee WK. PMID: 8625319.
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    219. Analysis of replication error (RER+) phenotypes in cervical carcinoma. Cancer Res. 1996 Mar 15; 56(6):1426-31. Larson AA, Kern S, Sommers RL, Yokota J, Cavenee WK, Hampton GM. PMID: 8640835.
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    220. A common region of loss of heterozygosity in Wilms' tumor and embryonal rhabdomyosarcoma distal to the D11S988 locus on chromosome 11p15.5. Hum Genet. 1996 Feb; 97(2):163-70. Besnard-Guérin C, Newsham I, Winqvist R, Cavenee WK. PMID: 8566947.
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    221. Molecular biology of malignant degeneration of astrocytoma. Pediatr Neurosurg. 1996; 24(1):41-9. Furnari FB, Huang HJ, Cavenee WK. PMID: 8817614.
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    222. The p53 gene and its role in human brain tumors. Glia. 1995 Nov; 15(3):308-27. Bögler O, Huang HJ, Kleihues P, Cavenee WK. PMID: 8586466.
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    223. EGFR gene amplification--rearrangement in human glioblastomas. Int J Cancer. 1995 Jul 17; 62(2):145-8. Schwechheimer K, Huang S, Cavenee WK. PMID: 7622287.
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    224. Definition and refinement of chromosome 11 regions of loss of heterozygosity in breast cancer: identification of a new region at 11q23.3. Cancer Res. 1995 Jul 15; 55(14):3003-7. Negrini M, Rasio D, Hampton GM, Sabbioni S, Rattan S, Carter SL, Rosenberg AL, Schwartz GF, Shiloh Y, Cavenee WK, et al. PMID: 7606718.
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    225. The t(11;22)(p15.5;q11.23) in a retroperitoneal rhabdoid tumor also includes a regional deletion distal to CRYBB2 on 22q. Genes Chromosomes Cancer. 1995 Jul; 13(3):145-50. Besnard-Guérin C, Cavenee W, Newsham I. PMID: 7669732.
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    226. Loss of wild-type p53 bestows a growth advantage on primary cortical astrocytes and facilitates their in vitro transformation. Cancer Res. 1995 Jul 01; 55(13):2746-51. Bögler O, Huang HJ, Cavenee WK. PMID: 7796398.
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    227. A defined region of loss of heterozygosity at 11q23 in cutaneous malignant melanoma. Cancer Res. 1995 Jun 15; 55(12):2494-6. Herbst RA, Larson A, Weiss J, Cavenee WK, Hampton GM, Arden KC. PMID: 7780954.
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    228. p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3. Nat Med. 1995 Jun; 1(6):570-7. Wales MM, Biel MA, el Deiry W, Nelkin BD, Issa JP, Cavenee WK, Kuerbitz SJ, Baylin SB. PMID: 7585125.
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    229. Loss of P16INK4 expression is frequent in high grade gliomas. Cancer Res. 1995 May 01; 55(9):1941-5. Nishikawa R, Furnari FB, Lin H, Arap W, Berger MS, Cavenee WK, Su Huang HJ. PMID: 7728764.
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    230. Replacement of the p16/CDKN2 gene suppresses human glioma cell growth. Cancer Res. 1995 Mar 15; 55(6):1351-4. Arap W, Nishikawa R, Furnari FB, Cavenee WK, Huang HJ. PMID: 7882335.
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    231. The genetic basis of cancer. Sci Am. 1995 Mar; 272(3):72-9. Cavenee WK, White RL. PMID: 7871410.
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    232. Single cell monitoring of growth arrest and morphological changes induced by transfer of wild-type p53 alleles to glioblastoma cells. Proc Natl Acad Sci U S A. 1995 Feb 14; 92(4):1008-12. Van Meir EG, Roemer K, Diserens AC, Kikuchi T, Rempel SA, Haas M, Huang HJ, Friedmann T, de Tribolet N, Cavenee WK. PMID: 7862624; PMCID: PMC42626.
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    233. Genetics and malignant progression of human brain tumours. Cancer Surv. 1995; 25:233-75. Furnari FB, Huang HJ, Cavenee WK. PMID: 8718522.
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    234. Genetics and cancer: a second look. Introduction. Cancer Surv. 1995; 25:1-2. Solomon E, Ponder BA, Cavenee WK. PMID: 8718509.
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    235. A constitutional BWS-related t(11;16) chromosome translocation occurring in the same region of chromosome 16 implicated in Wilms' tumors. Genes Chromosomes Cancer. 1995 Jan; 12(1):1-7. Newsham I, Kindler-Röhrborn A, Daub D, Cavenee W. PMID: 7534105.
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    236. Dinucleotide repeat polymorphism adjacent to CDKN2. Hum Mol Genet. 1994 Dec; 3(12):2265. Herbst RA, Nobori T, Cavenee WK, Carson DA, Arden KC. PMID: 7881438.
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    237. p53 gene mutation and mdm2 gene amplification are uncommon in medulloblastoma. Cancer Res. 1994 Nov 01; 54(21):5649-51. Adesina AM, Nalbantoglu J, Cavenee WK. PMID: 7923211.
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    238. Release of an inhibitor of angiogenesis upon induction of wild type p53 expression in glioblastoma cells. Nat Genet. 1994 Oct; 8(2):171-6. Van Meir EG, Polverini PJ, Chazin VR, Su Huang HJ, de Tribolet N, Cavenee WK. PMID: 7531056.
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    239. Loss of heterozygosity in sporadic human breast carcinoma: a common region between 11q22 and 11q23.3. Cancer Res. 1994 Sep 01; 54(17):4586-9. Hampton GM, Mannermaa A, Winqvist R, Alavaikko M, Blanco G, Taskinen PJ, Kiviniemi H, Newsham I, Cavenee WK, Evans GA, Winquist R. PMID: 8062246.
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    240. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7727-31. Nishikawa R, Ji XD, Harmon RC, Lazar CS, Gill GN, Cavenee WK, Huang HJ. PMID: 8052651; PMCID: PMC44475.
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    241. Loss of heterozygosity for 10q22-10qter in malignant melanoma progression. Cancer Res. 1994 Jun 15; 54(12):3111-4. Herbst RA, Weiss J, Ehnis A, Cavenee WK, Arden KC. PMID: 8205526.
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    242. A new highly polymorphic DNA restriction site marker in the 5' region of the human tyrosine hydroxylase gene (TH) detecting loss of heterozygosity in human embryonal rhabdomyosarcoma. Hum Genet. 1994 Mar; 93(3):349-50. Besnard-Guérin C, Cavenee WK, Newsham I. PMID: 7510263.
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    243. Molecular sublocalization and characterization of the 11;22 translocation breakpoint in a malignant rhabdoid tumor. Genomics. 1994 Feb; 19(3):433-40. Newsham I, Daub D, Besnard-Guerin C, Cavenee W. PMID: 8188285.
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    244. Analysis of the p53 gene and its expression in human glioblastoma cells. Cancer Res. 1994 Feb 01; 54(3):649-52. Van Meir EG, Kikuchi T, Tada M, Li H, Diserens AC, Wojcik BE, Huang HJ, Friedmann T, de Tribolet N, Cavenee WK. PMID: 8306326.
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    245. The RAP1GA1 locus for human Rap1-GTPase activating protein 1 maps to chromosome 1p36.1-->p35. Cytogenet Cell Genet. 1994; 66(1):18-21. Weiss J, Rubinfeld B, Polakis PG, McCormick F, Cavenee WK, Arden KC. PMID: 8275700.
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    246. Point mutations and allelic loss in the TP53 locus of cutaneous malignant melanomas. Arch Dermatol Res. 1994; 286(7):417-9. Weiss J, Cavenee WK, Herbst RA, Jung EG, Arden KC. PMID: 7818283.
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    247. Refinement of regional loss of heterozygosity for chromosome 11p15.5 in human breast tumors. Cancer Res. 1993 Oct 01; 53(19):4486-8. Winqvist R, Mannermaa A, Alavaikko M, Blanco G, Taskinen PJ, Kiviniemi H, Newsham I, Cavenee W. PMID: 8402619.
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    248. Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10. Hum Genet. 1993 Sep; 92(2):169-74. Karlbom AE, James CD, Boethius J, Cavenee WK, Collins VP, Nordenskjöld M, Larsson C. PMID: 8370584.
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    249. Homozygous inactivation of WT1 in a Wilms' tumor associated with the WAGR syndrome. Genes Chromosomes Cancer. 1993 Jul; 7(3):131-6. Gessler M, König A, Moore J, Qualman S, Arden K, Cavenee W, Bruns G. PMID: 7687865.
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    250. Mutation and expression of the p53 gene in malignant melanoma cell lines. Int J Cancer. 1993 Jun 19; 54(4):693-9. Weiss J, Schwechheimer K, Cavenee WK, Herlyn M, Arden KC. PMID: 8514460.
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    251. DNA hypermethylation is associated with 17p allelic loss in neural tumors. Cancer Res. 1993 Jun 15; 53(12):2715-8. Makos M, Nelkin BD, Chazin VR, Cavenee WK, Brodeur GM, Baylin SB. PMID: 8389241.
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    252. Genetics of cancer predisposition and progression. Clin Investig. 1993 Jun; 71(6):488-502. Schwechheimer K, Cavenee WK. PMID: 8353410.
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    253. Loss of heterozygosity for loci on chromosome 10 is associated with morphologically malignant meningioma progression. Cancer Res. 1993 May 15; 53(10 Suppl):2386-92. Rempel SA, Schwechheimer K, Davis RL, Cavenee WK, Rosenblum ML. PMID: 8485725.
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    254. A genetic linkage map with 29 loci spanning human chromosome 13q. Genomics. 1993 May; 16(2):515-9. Gerken S, Leppert M, O'Connell P, Cavenee W, James CD, Ballard L, Stauffer D, Elsner T, Plaetke R, Lalouel JM, et al. PMID: 8100218.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    255. Turcot's syndrome of glioma and polyposis occurs in the absence of germ line mutations of exons 5 to 9 of the p53 gene. Cancer Res. 1993 Mar 01; 53(5):957-61. Kikuchi T, Rempel SA, Rutz HP, de Tribolet N, Mulligan L, Cavenee WK, Jothy S, Leduy L, Van Meir EG. PMID: 8439970.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    256. Tumors and developmental anomalies associated with Wilms tumor. Med Pediatr Oncol. 1993; 21(3):199-204. Newsham I, Cavenee W. PMID: 8383280.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    257. Characterization of polymorphic and monomorphic loci for chromosome 11p15.5. Mamm Genome. 1993; 4(8):451-3. Newsham I, Artigas C, Lasko D, Cavenee W. PMID: 8104058.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    258. A siren song from tumor cells. J Clin Invest. 1993 Jan; 91(1):3. Cavenee WK. PMID: 7678605; PMCID: PMC329986.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    259. Retinoblastoma and p53 gene product expression in breast carcinoma: immunohistochemical analysis and clinicopathologic correlation. Hum Pathol. 1992 Dec; 23(12):1388-94. Trudel M, Mulligan L, Cavenee W, Margolese R, Côté J, Gariépy G. PMID: 1468776.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    260. Gliomas in families. Can J Neurol Sci. 1992 Nov; 19(4):492-7. Ikizler Y, van Meyel DJ, Ramsay DA, Abdallah GL, Allaster RM, Macdonald DR, Cavenee WK, Cairncross JG. PMID: 1423046.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    261. Accumulation of genetic defects during astrocytoma progression. Cancer. 1992 Sep 15; 70(6 Suppl):1788-93. Cavenee WK. PMID: 1325281.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    262. Loss of heterozygosity for chromosomes 1 or 14 defines subsets of advanced neuroblastomas. Cancer Res. 1992 Apr 01; 52(7):1780-5. Fong CT, White PS, Peterson K, Sapienza C, Cavenee WK, Kern SE, Vogelstein B, Cantor AB, Look AT, Brodeur GM. PMID: 1551108.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    263. Human chromosome 11 contains two different growth suppressor genes for embryonal rhabdomyosarcoma. Proc Natl Acad Sci U S A. 1992 Mar 01; 89(5):1755-9. Loh WE, Scrable HJ, Livanos E, Arboleda MJ, Cavenee WK, Oshimura M, Weissman BE. PMID: 1347425; PMCID: PMC48531.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    264. Developmental genetics and childhood cancer. AACR special conference in cancer research. Cancer Res. 1991 Oct 01; 51(19):5435-9. Knudson A, Vande Woude GF, Friend SH, Cavenee WK, Brodeur GM. PMID: 1655251.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    265. Muscle-specific gene expression in rhabdomyosarcomas and stages of human fetal skeletal muscle development. Cancer Res. 1991 Oct 01; 51(19):5100-6. Tonin PN, Scrable H, Shimada H, Cavenee WK. PMID: 1717137.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    266. Charles S. Mott Prize. Recessive mutations in the causation of human cancer. Cancer. 1991 May 15; 67(10):2431-5. Cavenee WK. PMID: 2015543.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    267. Genetics of the malignant progression of astrocytoma. J Cell Biochem. 1991 May; 46(1):3-8. Mikkelsen T, Cairncross JG, Cavenee WK. PMID: 1874797.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    268. Genes for epidermal growth factor receptor, transforming growth factor alpha, and epidermal growth factor and their expression in human gliomas in vivo. Cancer Res. 1991 Apr 15; 51(8):2164-72. Ekstrand AJ, James CD, Cavenee WK, Seliger B, Pettersson RF, Collins VP. PMID: 2009534.
      View in: PubMed   Mentions: 193     Fields:    Translation:Humans
    269. Molecular genetics of human cancer predisposition and progression. Mutat Res. 1991 Apr; 247(2):199-202. Cavenee WK, Scrable HJ, James CD. PMID: 2011137.
      View in: PubMed   Mentions: 11     Fields:    Translation:Humans
    270. Chromosome 9 deletion mapping reveals interferon alpha and interferon beta-1 gene deletions in human glial tumors. Cancer Res. 1991 Mar 15; 51(6):1684-8. James CD, He J, Carlbom E, Nordenskjold M, Cavenee WK, Collins VP. PMID: 1998958.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    271. Microdissection of chromosome band 11p15.5: characterization of probes mapping distal to the HBBC locus. Genes Chromosomes Cancer. 1991 Mar; 3(2):108-16. Newsham I, Claussen U, Lüdecke HJ, Mason M, Senger G, Horsthemke B, Cavenee W. PMID: 1676905.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    272. Cloning and expression of the cDNA encoding human fumarylacetoacetate hydrolase, the enzyme deficient in hereditary tyrosinemia: assignment of the gene to chromosome 15. Am J Hum Genet. 1991 Mar; 48(3):525-35. Phaneuf D, Labelle Y, Bérubé D, Arden K, Cavenee W, Gagné R, Tanguay RM. PMID: 1998338; PMCID: PMC1682993.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansAnimalsCells
    273. A polymorphism of D13S86 from the region 13q14.1 to 13q22. Nucleic Acids Res. 1991 Feb 11; 19(3):684. McHaffie NP, Houwen R, Cavenee W, Cox DW. PMID: 1672759; PMCID: PMC333677.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    274. Genetics and cancer. Eur J Cancer. 1991; 27(12):1706-7. Cavenee WK, Ponder B, Solomon E. PMID: 1782088.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    275. Isolation and regional localization of 25 anonymous DNA probes on a chromosome 13 hybrid panel. Cytogenet Cell Genet. 1991; 57(2-3):87-90. Houwen RH, Pautler SE, Barwell JA, Arden K, Buchanan JA, James CD, Cavenee WK, Buys CH, Cowell JK, Cox DW. PMID: 1914527.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    276. Loss of constitutional heterozygosity in human cancer. Annu Rev Genet. 1991; 25:281-314. Lasko D, Cavenee W, Nordenskjöld M. PMID: 1687498.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    277. Recessive mutations in cancer predisposition and progression. Basic Life Sci. 1991; 57:171-80; discussion 180-1. Cavenee WK. PMID: 1667571.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    278. Structural alterations at the putative retinoblastoma locus in some human leukemias and preleukemia. Cancer Genet Cytogenet. 1990 Oct 01; 49(1):15-23. Hansen MF, Morgan R, Sandberg AA, Cavenee WK. PMID: 2397469.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    279. Molecular genetics in the pathology and diagnosis of retinoblastoma. Brain Pathol. 1990 Sep; 1(1):25-32. Gennett IN, Cavenee WK. PMID: 1669690.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    280. Mechanisms of p53 loss in human sarcomas. Proc Natl Acad Sci U S A. 1990 Aug; 87(15):5863-7. Mulligan LM, Matlashewski GJ, Scrable HJ, Cavenee WK. PMID: 2143022; PMCID: PMC54429.
      View in: PubMed   Mentions: 70     Fields:    Translation:HumansAnimalsCells
    281. Loss of genetic information in central nervous system tumors common to children and young adults. Genes Chromosomes Cancer. 1990 Jul; 2(2):94-102. James CD, He J, Carlbom E, Mikkelsen T, Ridderheim PA, Cavenee WK, Collins VP. PMID: 1980610.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    282. Suppressors of the malignant phenotype. Cell Growth Differ. 1990 Apr; 1(4):201-7. Mikkelsen T, Cavenee WK. PMID: 2128032.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    283. Rhabdomyosarcoma-associated locus and MYOD1 are syntenic but separate loci on the short arm of human chromosome 11. Proc Natl Acad Sci U S A. 1990 Mar; 87(6):2182-6. Scrable HJ, Johnson DK, Rinchik EM, Cavenee WK. PMID: 2315312; PMCID: PMC53650.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    284. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature. 1990 Feb 22; 343(6260):774-8. Gessler M, Poustka A, Cavenee W, Neve RL, Orkin SH, Bruns GA. PMID: 2154702.
      View in: PubMed   Mentions: 296     Fields:    Translation:HumansCells
    285. Molecular genetic aspects of glial tumour evolution. Cancer Surv. 1990; 9(4):631-44. James CD, Mikkelsen T, Cavenee WK, Collins VP. PMID: 1983210.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    286. The receptors for prolactin and growth hormone are localized in the same region of human chromosome 5. Cytogenet Cell Genet. 1990; 53(2-3):161-5. Arden KC, Boutin JM, Djiane J, Kelly PA, Cavenee WK. PMID: 2369845.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansCells
    287. Genetic and epigenetic losses of heterozygosity in cancer predisposition and progression. Adv Cancer Res. 1990; 54:25-62. Scrable HJ, Sapienza C, Cavenee WK. PMID: 2404380.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    288. A model for embryonal rhabdomyosarcoma tumorigenesis that involves genome imprinting. Proc Natl Acad Sci U S A. 1989 Oct; 86(19):7480-4. Scrable H, Cavenee W, Ghavimi F, Lovell M, Morgan K, Sapienza C. PMID: 2798419; PMCID: PMC298088.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansCells
    289. Concordant deletions of chromosome 3p and loss of heterozygosity for chromosomes 13 and 17 in small cell lung carcinoma. Cancer Res. 1989 Sep 15; 49(18):5130-5. Mori N, Yokota J, Oshimura M, Cavenee WK, Mizoguchi H, Noguchi M, Shimosato Y, Sugimura T, Terada M. PMID: 2569931.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    290. Molecular differential pathology of rhabdomyosarcoma. Genes Chromosomes Cancer. 1989 Sep; 1(1):23-35. Scrable H, Witte D, Shimada H, Seemayer T, Sheng WW, Soukup S, Koufos A, Houghton P, Lampkin B, Cavenee W. PMID: 2487144.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCells
    291. Loss of heterozygosity in stages of malignancy. Clin Chem. 1989 Jul; 35(7 Suppl):B48-52. Cavenee WK. PMID: 2663235.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    292. Familial Wiedemann-Beckwith syndrome and a second Wilms tumor locus both map to 11p15.5. Am J Hum Genet. 1989 May; 44(5):711-9. Koufos A, Grundy P, Morgan K, Aleck KA, Hadro T, Lampkin BC, Kalbakji A, Cavenee WK. PMID: 2539717; PMCID: PMC1715635.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    293. Molecular mechanisms of oncogenesis. Lab Invest. 1989 May; 60(5):585-99. Seemayer TA, Cavenee WK. PMID: 2654471.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    294. Mitotic recombination of chromosome 17 in astrocytomas. Proc Natl Acad Sci U S A. 1989 Apr; 86(8):2858-62. James CD, Carlbom E, Nordenskjold M, Collins VP, Cavenee WK. PMID: 2565039; PMCID: PMC287018.
      View in: PubMed   Mentions: 71     Fields:    Translation:HumansCells
    295. Molecular detection of chromosomal translocations that disrupt the putative retinoblastoma susceptibility locus. Mol Cell Biol. 1989 Jan; 9(1):1-5. Higgins MJ, Hansen MF, Cavenee WK, Lalande M. PMID: 2927388; PMCID: PMC362138.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCells
    296. The chromosome 11 region flanking the t(11;14) breakpoint in human T-ALL is deleted in Wilms' tumor hybrids. Oncogene Res. 1989; 5(2):143-8. Finver SN, Martiniere C, Kagan J, Cavenee W, Croce CM. PMID: 2558334.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    297. Tumor progression stage: specific losses of heterozygosity. Princess Takamatsu Symp. 1989; 20:33-42. Cavenee WK. PMID: 2488236.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    298. Mitotic abnormalities leading to cancer predisposition and progression. Cancer Detect Prev. 1989; 14(2):269-73. Cavenee WK. PMID: 2559800.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    299. Loss of genetic information in cancer. Ciba Found Symp. 1989; 142:79-88; discussion 88-92. Cavenee WK, Hansen MF, Scrable HJ, James CD. PMID: 2743836.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    300. Current knowledge of heritable tumors. Birth Defects Orig Artic Ser. 1989; 25(2):29-43. Cavenee WK. PMID: 2655740.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    301. Familial predisposition to Wilms' tumour does not map to the short arm of chromosome 11. Nature. 1988 Nov 24; 336(6197):374-6. Grundy P, Koufos A, Morgan K, Li FP, Meadows AT, Cavenee WK. PMID: 2848199.
      View in: PubMed   Mentions: 46     Fields:    Translation:HumansCells
    302. Clonal genomic alterations in glioma malignancy stages. Cancer Res. 1988 Oct 01; 48(19):5546-51. James CD, Carlbom E, Dumanski JP, Hansen M, Nordenskjold M, Collins VP, Cavenee WK. PMID: 2901288.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    303. Retinoblastoma and the progression of tumor genetics. Trends Genet. 1988 May; 4(5):125-8. Hansen MF, Cavenee WK. PMID: 3070862.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    304. Tumor suppressors: recessive mutations that lead to cancer. Cell. 1988 Apr 22; 53(2):173-4. Hansen MF, Cavenee WK. PMID: 3282673.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimals
    305. A polymorphic DNA marker on chromosome 10 linked to RBP3 on the MEN2A side. Cytogenet Cell Genet. 1988; 48(4):246-7. Wu J, Cavenee WK, Miki T, Kidd KK. PMID: 2907872.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    306. Genetics and the etiology of solid tumors. Important Adv Oncol. 1988; 83-101. Nordenskjold M, Cavenee WK. PMID: 3042611.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    307. Genetics of cancer predisposition. Cancer Res. 1987 Nov 01; 47(21):5518-27. Hansen MF, Cavenee WK. PMID: 2889524.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    308. Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping. Nature. 1987 Oct 15-21; 329(6140):645-7. Scrable HJ, Witte DP, Lampkin BC, Cavenee WK. PMID: 3657988.
      View in: PubMed   Mentions: 83     Fields:    Translation:Humans
    309. Genetic markers for assessment of retinoblastoma predisposition. Dis Markers. 1987 Sep; 5(3):141-52. Buchanan JA, Cavenee WK. PMID: 3332257.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    310. Retinoblastoma and osteosarcoma: the prototypic cancer family. Acta Paediatr Jpn. 1987 Aug; 29(4):526-33. Hansen MF, Cavenee WK. PMID: 3144887.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    311. Tissue-specific and developmentally regulated transcription of the insulin-like growth factor 2 gene. DNA. 1987 Aug; 6(4):283-95. Gray A, Tam AW, Dull TJ, Hayflick J, Pintar J, Cavenee WK, Koufos A, Ullrich A. PMID: 3652904.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    312. Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13. Proc Natl Acad Sci U S A. 1987 Apr; 84(8):2372-6. Lundberg C, Skoog L, Cavenee WK, Nordenskjöld M. PMID: 3031679; PMCID: PMC304653.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    313. Human collagen genes encoding basement membrane alpha 1 (IV) and alpha 2 (IV) chains map to the distal long arm of chromosome 13. Proc Natl Acad Sci U S A. 1987 Jan; 84(2):512-6. Griffin CA, Emanuel BS, Hansen JR, Cavenee WK, Myers JC. PMID: 3025878; PMCID: PMC304239.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    314. Identification of recessive mutations at human cancer loci. Birth Defects Orig Artic Ser. 1987; 23(3):93-107. Cavenee WK. PMID: 2820528.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    315. A primary genetic map of chromosome 13q. Am J Hum Genet. 1986 Oct; 39(4):425-37. Leppert M, Cavenee W, Callahan P, Holm T, O'Connell P, Thompson K, Lathrop GM, Lalouel JM, White R. PMID: 3464200; PMCID: PMC1683981.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    316. Recessive mutant genes predisposing to human cancer. Mutat Res. 1986 Jul; 168(1):3-14. Cavenee WK, Koufos A, Hansen MF. PMID: 3012326.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    317. Prediction of familial predisposition to retinoblastoma. N Engl J Med. 1986 May 08; 314(19):1201-7. Cavenee WK, Murphree AL, Shull MM, Benedict WF, Sparkes RS, Kock E, Nordenskjold M. PMID: 3702916.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    318. Molecular genetics of human familial cancer. Cold Spring Harb Symp Quant Biol. 1986; 51 Pt 2:829-35. Cavenee WK, Hansen MF. PMID: 3472764.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    319. Chromosome 13 homozygosity in osteosarcoma without retinoblastoma. Am J Hum Genet. 1986 Jan; 38(1):59-66. Dryja TP, Rapaport JM, Epstein J, Goorin AM, Weichselbaum R, Koufos A, Cavenee WK. PMID: 3004203; PMCID: PMC1684712.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    320. Recessive mutant genes predisposing to human cancer. Prog Clin Biol Res. 1986; 209A:575-82. Cavenee WK. PMID: 3749067.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    321. Chromosomal mechanisms in the initiation of human familial mixed cancers. Princess Takamatsu Symp. 1986; 17:171-9. Cavenee WK. PMID: 3332009.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    322. Osteosarcoma and retinoblastoma: a shared chromosomal mechanism revealing recessive predisposition. Proc Natl Acad Sci U S A. 1985 Sep; 82(18):6216-20. Hansen MF, Koufos A, Gallie BL, Phillips RA, Fodstad O, Brøgger A, Gedde-Dahl T, Cavenee WK. PMID: 2994066; PMCID: PMC391023.
      View in: PubMed   Mentions: 99     Fields:    Translation:HumansCells
    323. Loss of heterozygosity in three embryonal tumours suggests a common pathogenetic mechanism. Nature. 1985 Jul 25-31; 316(6026):330-4. Koufos A, Hansen MF, Copeland NG, Jenkins NA, Lampkin BC, Cavenee WK. PMID: 2991766.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansAnimalsCells
    324. Genetic origin of mutations predisposing to retinoblastoma. Science. 1985 Apr 26; 228(4698):501-3. Cavenee WK, Hansen MF, Nordenskjold M, Kock E, Maumenee I, Squire JA, Phillips RA, Gallie BL. PMID: 3983638.
      View in: PubMed   Mentions: 68     Fields:    Translation:HumansCells
    325. Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour. Nature. 1984 May 10-16; 309(5964):170-2. Koufos A, Hansen MF, Lampkin BC, Workman ML, Copeland NG, Jenkins NA, Cavenee WK. PMID: 6325936.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCells
    326. [Carrier diagnosis of retinoblastoma with molecular genetic methods]. Lakartidningen. 1984 Mar 21; 81(12):1183-92. Nordenskjöld M, Cavenee WK, Kumlin E, Kock E. PMID: 6369047.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    327. Homozygosity of chromosome 13 in retinoblastoma. N Engl J Med. 1984 Mar 01; 310(9):550-3. Dryja TP, Cavenee W, White R, Rapaport JM, Petersen R, Albert DM, Bruns GA. PMID: 6694706.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    328. Isolation and regional localization of DNA segments revealing polymorphic loci from human chromosome 13. Am J Hum Genet. 1984 Jan; 36(1):10-24. Cavenee W, Leach R, Mohandas T, Pearson P, White R. PMID: 6320640; PMCID: PMC1684373.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansAnimalsCells
    329. Expression of recessive alleles by chromosomal mechanisms in retinoblastoma. Nature. 1983 Oct 27-Nov 2; 305(5937):779-84. Cavenee WK, Dryja TP, Phillips RA, Benedict WF, Godbout R, Gallie BL, Murphree AL, Strong LC, White RL. PMID: 6633649.
      View in: PubMed   Mentions: 448     Fields:    Translation:HumansCells
    330. Characterization of dominant hamster cell mutants resistant to oxygenated sterols. Somatic Cell Genet. 1982 Sep; 8(5):557-74. Cavenee WK, Baker RM. PMID: 7135162.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    331. Regulation of cholesterol biosynthesis in enucleated cells. J Biol Chem. 1981 Mar 25; 256(6):2675-81. Cavenee WK, Chen HW, Kandutsch AA. PMID: 7204371.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    332. Cell-substratum and cell-monolayer adhesion are dependent upon cellular cholesterol biosynthesis. Exp Cell Res. 1981 Jan; 131(1):31-40. Cavenee WK, Chen HW, Kandutsch AA. PMID: 7447988.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    333. Regulation of cholesterol biosynthesis in cultured cells by probable natural precursor sterols. J Biol Chem. 1980 Jan 25; 255(2):395-400. Gibbons GF, Pullinger CR, Chen HW, Cavenee WK, Kandutsch AA. PMID: 7356622.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    334. Effects of various oxygenated sterols on cellular sterol biosynthesis in Chinese hamster lung cells resistant to 25-hydroxycholesterol. Biochim Biophys Acta. 1979 Nov 21; 575(2):255-65. Cavenee WK, Gibbons GF, Chen HW, Kandutsch AA. PMID: 508785.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    335. Sterol synthesis in variant Chinese hamster lung cells selected for resistance to 25-hydroxycholesterol. Cross-resistance to 7-ketocholesterol, 20alpha-hydroxycholesterol, and serum. J Biol Chem. 1979 Feb 10; 254(3):715-20. Chen HW, Cavenee WK, Kandutsch AA. PMID: 762093.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    336. Cholesterol biosynthesis in a variety of cultured cells. Lack of correlation between synthesis and activity of 3-hydroxy-3-methylglutaryl coenzyme A reductase caused by dexamethasone. Biochim Biophys Acta. 1979 Jan 29; 572(1):188-92. Johnston D, Cavenee WK, Ramachandran CK, Melnykovych G. PMID: 760799.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    337. Elevation of HeLa cell 3-hydroxy-3-methylglutaryl coenzyme A reductase activity by glucocorticoids: possible relationship to the cell cycle. J Cell Physiol. 1979 Jan; 98(1):199-211. Cavenee WK, Melnykovych G. PMID: 762197.
      View in: PubMed   Mentions:    Fields:    Translation:Cells
    338. Regulation of cholesterol biosynthesis in HeLa S3G cells by serum lipoproteins: dexamethasone-mediated interference with suppression of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Proc Natl Acad Sci U S A. 1978 May; 75(5):2103-7. Cavenee WK, Johnston D, Melnykovych G. PMID: 209449; PMCID: PMC392499.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    339. Induction of 3-hydroxy-3-methylglutaryl coenzyme A reductase in HeLa cells by glucocorticoids. J Biol Chem. 1977 May 25; 252(10):3272-6. Cavenee WK, Melnykovych G. PMID: 16889.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
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