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Richard Kolodner

Title(s)Professor, Cellular and Molecular Medicine
SchoolHealth Sciences
Phone858-534-7804
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    Our laboratory is studying the genetic and biochemical mechanisms of genetic recombination, DNA repair and suppression of spontaneous mutations primarily using Saccharomyces cerevisiae as a model system. Work in S. cerevisiae falls in two interrelated areas - 1) the analysis of the proteins and genes that function in DNA mismatch repair; and 2) elucidation of the pathways that prevent translocations and other types of gross chromosomal rearrangements, and the analysis of the proteins that function in these pathways. The Kolodner lab also has research interests in the area of investigating the genetics of cancer susceptibility and development that follows on previous studies showing that a common cancer susceptibility syndrome, Lynch Syndrome (hereditary non-polyposis colorectal cancer), is due to inherited defects in DNA mismatch repair genes. This work is focused on understanding whether genes that prevent genome instability act as tumor suppressor genes in humans and whether defects in these genes can be therapeutically targeted.

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    SHARED MOLECULAR BIOLOGY FACILITY EQUIPMENT
    NIH/NCRR S10RR004895Mar 13, 1989 - Mar 12, 1990
    Role: Principal Investigator
    Enzymology of Mismatch Repair in Yeast
    NIH/NIGMS R01GM050006Jul 1, 1988 - Nov 30, 2022
    Role: Principal Investigator
    ENZYMOLOGY OF MISMATCH REPAIR IN YEAST
    NIH/NHGRI R01HG000305Jul 1, 1988 - Jun 30, 1994
    Role: Principal Investigator
    ENZYMOLOGY OF MISMATCH REPAIR IN YEAST
    NIH/NIGMS R01GM040554Jul 1, 1988 - Jun 30, 1993
    Role: Principal Investigator
    ENZYMATIC MECHANISMS OF GENETIC RECOMBINATION IN YEAST
    NIH/NIGMS R01GM029383Jul 1, 1983 - Jun 30, 1996
    Role: Principal Investigator
    Tumor Cell Biology Training Program
    NIH/NCI T32CA009361Jul 1, 1980 - Jun 30, 2016
    Role: Co-Principal Investigator
    Enzymatic Mechanisms of Genetic Recombination
    NIH/NIGMS R01GM026017Dec 1, 1978 - Mar 31, 2022
    Role: Principal Investigator
    ENZYMATIC MECHANISMS OF GENETIC RECOMBINATION
    NIH/NIGMS R37GM026017Dec 1, 1978 - Mar 31, 2002
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Srivatsan A, Li B, Sanchez DN, Somach SB, da Silva VL, de Souza SJ, Putnam CD, Kolodner RD. Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors. Proc Natl Acad Sci U S A. 2019 Aug 27; 116(35):17377-17382. PMID: 31409704.
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    2. Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Alternative splicing regulates stochastic NLRP3 activity. Nat Commun. 2019 Jul 19; 10(1):3238. PMID: 31324763.
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    3. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 May 13; 35(5):816. PMID: 31085179.
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    4. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 Mar 18; 35(3):504-518.e7. PMID: 30827889.
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    5. Klein HL, Bacinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, Polleys EJ, Putnam CD, Radchenko EA, Saada AA, Sakofsky CJ, Shim EY, Stracy M, Xia J, Yan Z, Yin Y, Aguilera A, Argueso JL, Freudenreich CH, Gasser SM, Gordenin DA, Haber JE, Ira G, Jinks-Robertson S, King MC, Kolodner RD, Kuzminov A, Lambert SA, Lee SE, Miller KM, Mirkin SM, Petes TD, Rosenberg SM, Rothstein R, Symington LS, Zawadzki P, Kim N, Lisby M, Malkova A. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microb Cell. 2019 Jan 07; 6(1):1-64. PMID: 30652105.
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    6. Graham WJ, Putnam CD, Kolodner RD. The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair. J Biol Chem. 2018 11 23; 293(47):18055-18070. PMID: 30237169.
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    7. Srivatsan A, Li BZ, Szakal B, Branzei D, Putnam CD, Kolodner RD. The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. Nat Commun. 2018 09 11; 9(1):3680. PMID: 30206225.
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    8. Goellner EM, Putnam CD, Graham WJ, Rahal CM, Li BZ, Kolodner RD. Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners. Nat Struct Mol Biol. 2018 Aug; 25(8):650-659. PMID: 30061603.
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    9. Liang J, Li BZ, Tan AP, Kolodner RD, Putnam CD, Zhou H. SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements. PLoS Genet. 2018 03; 14(3):e1007250. PMID: 29505562.
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    10. Nene RV, Putnam CD, Li BZ, Nguyen KG, Srivatsan A, Campbell CS, Desai A, Kolodner RD. Cdc73 suppresses genome instability by mediating telomere homeostasis. PLoS Genet. 2018 01; 14(1):e1007170. PMID: 29320491.
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    11. Srivatsan A, Putnam CD, Kolodner RD. Analyzing Genome Rearrangements in Saccharomyces cerevisiae. Methods Mol Biol. 2018; 1672:43-61. PMID: 29043616.
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    12. Putnam CD, Kolodner RD. Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae. Genetics. 2017 07; 206(3):1187-1225. PMID: 28684602.
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    13. Bowen N, Kolodner RD. Reconstitution of Saccharomyces cerevisiae DNA polymerase e-dependent mismatch repair with purified proteins. Proc Natl Acad Sci U S A. 2017 04 04; 114(14):3607-3612. PMID: 28265089.
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    14. Breuss MW, Nguyen T, Srivatsan A, Leca I, Tian G, Fritz T, Hansen AH, Musaev D, McEvoy-Venneri J, James KN, Rosti RO, Scott E, Tan U, Kolodner RD, Cowan NJ, Keays DA, Gleeson JG. Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Hum Mol Genet. 2017 01 15; 26(2):258-269. PMID: 28013290.
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    15. Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H. Correction: Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements. PLoS Genet. 2016 Aug; 12(8):e1006302. PMID: 27579875.
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    16. Putnam CD, Srivatsan A, Nene RV, Martinez SL, Clotfelter SP, Bell SN, Somach SB, de Souza JE, Fonseca AF, de Souza SJ, Kolodner RD. A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers. Nat Commun. 2016 Apr 13; 7:11256. PMID: 27071721.
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    17. Kolodner RD. A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair. DNA Repair (Amst). 2016 Feb; 38:3-13. PMID: 26698650.
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    18. Smith CE, Bowen N, Graham WJ, Goellner EM, Srivatsan A, Kolodner RD. Activation of Saccharomyces cerevisiae Mlh1-Pms1 Endonuclease in a Reconstituted Mismatch Repair System. J Biol Chem. 2015 Aug 28; 290(35):21580-90. PMID: 26170454.
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    19. Goellner EM, Putnam CD, Kolodner RD. Exonuclease 1-dependent and independent mismatch repair. DNA Repair (Amst). 2015 Aug; 32:24-32. PMID: 25956862.
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    20. Reyes GX, Schmidt TT, Kolodner RD, Hombauer H. New insights into the mechanism of DNA mismatch repair. Chromosoma. 2015 Dec; 124(4):443-62. PMID: 25862369.
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    21. Ragu S, Dardalhon M, Sharma S, Iraqui I, Buhagiar-Labarchède G, Grondin V, Kienda G, Vernis L, Chanet R, Kolodner RD, Huang ME, Faye G. Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants. PLoS One. 2014; 9(9):e108123. PMID: 25247923.
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    22. Goellner EM, Smith CE, Campbell CS, Hombauer H, Desai A, Putnam CD, Kolodner RD. PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. Mol Cell. 2014 Jul 17; 55(2):291-304. PMID: 24981171.
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    23. Campbell CS, Hombauer H, Srivatsan A, Bowen N, Gries K, Desai A, Putnam CD, Kolodner RD. Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae. PLoS Genet. 2014 May; 10(5):e1004327. PMID: 24811092.
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    24. de Souza JE, Fonseca AF, Valieris R, Carraro DM, Wang JY, Kolodner RD, de Souza SJ. S-score: a scoring system for the identification and prioritization of predicted cancer genes. PLoS One. 2014; 9(4):e94147. PMID: 24710071.
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    25. Putnam CD, Pallis K, Hayes TK, Kolodner RD. DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures. PLoS Genet. 2014 Apr; 10(4):e1004277. PMID: 24699249.
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    26. Allen-Soltero S, Martinez SL, Putnam CD, Kolodner RD. A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability. Mol Cell Biol. 2014 Apr; 34(8):1521-34. PMID: 24550002.
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    27. Srivatsan A, Bowen N, Kolodner RD. Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex. J Biol Chem. 2014 Mar 28; 289(13):9352-64. PMID: 24550389.
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    28. Bowen N, Smith CE, Srivatsan A, Willcox S, Griffith JD, Kolodner RD. Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins. Proc Natl Acad Sci U S A. 2013 Nov 12; 110(46):18472-7. PMID: 24187148.
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    29. Smith CE, Mendillo ML, Bowen N, Hombauer H, Campbell CS, Desai A, Putnam CD, Kolodner RD. Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway. PLoS Genet. 2013 Oct; 9(10):e1003869. PMID: 24204293.
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    30. Hura GL, Tsai CL, Claridge SA, Mendillo ML, Smith JM, Williams GJ, Mastroianni AJ, Alivisatos AP, Putnam CD, Kolodner RD, Tainer JA. DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals. Proc Natl Acad Sci U S A. 2013 Oct 22; 110(43):17308-13. PMID: 24101514.
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    31. Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H. Distinct SUMO ligases cooperate with Esc2 and Slx5 to suppress duplication-mediated genome rearrangements. PLoS Genet. 2013; 9(8):e1003670. PMID: 23935535.
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    32. Jaehnig EJ, Kuo D, Hombauer H, Ideker TG, Kolodner RD. Checkpoint kinases regulate a global network of transcription factors in response to DNA damage. Cell Rep. 2013 Jul 11; 4(1):174-88. PMID: 23810556.
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    33. Putnam CD, Allen-Soltero SR, Martinez SL, Chan JE, Hayes TK, Kolodner RD. Bioinformatic identification of genes suppressing genome instability. Proc Natl Acad Sci U S A. 2012 Nov 20; 109(47):E3251-9. PMID: 23129647.
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    34. Hargreaves VV, Putnam CD, Kolodner RD. Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair. J Biol Chem. 2012 Nov 30; 287(49):41232-44. PMID: 23045530.
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    35. Chan JE, Kolodner RD. Rapid analysis of Saccharomyces cerevisiae genome rearrangements by multiplex ligation-dependent probe amplification. PLoS Genet. 2012; 8(3):e1002539. PMID: 22396658.
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    36. Enserink JM, Kolodner RD. What makes the engine hum: Rad6, a cell cycle supercharger. Cell Cycle. 2012 Jan 15; 11(2):249-52. PMID: 22214660.
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    37. Hombauer H, Srivatsan A, Putnam CD, Kolodner RD. Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication. Science. 2011 Dec 23; 334(6063):1713-6. PMID: 22194578.
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    38. Hombauer H, Campbell CS, Smith CE, Desai A, Kolodner RD. Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates. Cell. 2011 Nov 23; 147(5):1040-53. PMID: 22118461.
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    39. Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM. A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18748-53. PMID: 22042866.
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    40. Kolodner RD, Cleveland DW, Putnam CD. Cancer. Aneuploidy drives a mutator phenotype in cancer. Science. 2011 Aug 19; 333(6045):942-3. PMID: 21852477.
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    41. Chan JE, Kolodner RD. A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements. PLoS Genet. 2011 May; 7(5):e1002089. PMID: 21637792.
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    42. Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shokat KM, Kolodner RD, Huh WK, Aebersold R, Keogh MC, Krogan NJ, Ideker T. Rewiring of genetic networks in response to DNA damage. Science. 2010 Dec 03; 330(6009):1385-9. PMID: 21127252.
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    43. Putnam CD, Kolodner RD. Determination of gross chromosomal rearrangement rates. Cold Spring Harb Protoc. 2010 Sep 01; 2010(9):pdb.prot5492. PMID: 20810639.
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    44. Wang Y, Huang B, Edelmann L, Kolodner RD, Edelmann W. Genes essential for cell viability that are linked to tumor suppressor genes play a role in cancer susceptibility. Cell Cycle. 2010 Aug 15; 9(16):3144-5. PMID: 20703099.
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    45. Enserink JM, Kolodner RD. An overview of Cdk1-controlled targets and processes. Cell Div. 2010 May 13; 5:11. PMID: 20465793.
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    46. Putnam CD, Hayes TK, Kolodner RD. Post-replication repair suppresses duplication-mediated genome instability. PLoS Genet. 2010 May 06; 6(5):e1000933. PMID: 20463880.
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    47. Dowen JM, Putnam CD, Kolodner RD. Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation. Mol Cell Biol. 2010 Jul; 30(13):3321-8. PMID: 20421420.
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    48. Wang Y, Zhang W, Edelmann L, Kolodner RD, Kucherlapati R, Edelmann W. Cis lethal genetic interactions attenuate and alter p53 tumorigenesis. Proc Natl Acad Sci U S A. 2010 Mar 23; 107(12):5511-5. PMID: 20212136.
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    49. Mendillo ML, Putnam CD, Mo AO, Jamison JW, Li S, Woods VL, Kolodner RD. Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry. J Biol Chem. 2010 Apr 23; 285(17):13170-82. PMID: 20181951.
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    50. Martinez SL, Kolodner RD. Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):5070-5. PMID: 20176959.
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    51. Hargreaves VV, Shell SS, Mazur DJ, Hess MT, Kolodner RD. Interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharomyces cerevisiae Msh2-Msh6 complex. J Biol Chem. 2010 Mar 19; 285(12):9301-10. PMID: 20089866.
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    52. Mendillo ML, Hargreaves VV, Jamison JW, Mo AO, Li S, Putnam CD, Woods VL, Kolodner RD. A conserved MutS homolog connector domain interface interacts with MutL homologs. Proc Natl Acad Sci U S A. 2009 Dec 29; 106(52):22223-8. PMID: 20080788.
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    53. Mueller J, Gazzoli I, Bandipalliam P, Garber JE, Syngal S, Kolodner RD. Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases. Cancer Res. 2009 Sep 01; 69(17):7053-61. PMID: 19690142.
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    54. Putnam CD, Hayes TK, Kolodner RD. Specific pathways prevent duplication-mediated genome rearrangements. Nature. 2009 Aug 20; 460(7258):984-9. PMID: 19641493.
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    55. Pennaneach V, Kolodner RD. Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae. PLoS One. 2009 Jul 28; 4(7):e6389. PMID: 19636429.
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    56. Kats ES, Enserink JM, Martinez S, Kolodner RD. The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants. Mol Cell Biol. 2009 Oct; 29(19):5226-37. PMID: 19635810.
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    57. Iraqui I, Kienda G, Soeur J, Faye G, Baldacci G, Kolodner RD, Huang ME. Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae. PLoS Genet. 2009 Jun; 5(6):e1000524. PMID: 19543365.
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    58. Putnam CD, Jaehnig EJ, Kolodner RD. Perspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae. DNA Repair (Amst). 2009 Sep 02; 8(9):974-82. PMID: 19477695.
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    59. Enserink JM, Hombauer H, Huang ME, Kolodner RD. Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae. J Cell Biol. 2009 May 04; 185(3):423-37. PMID: 19398760.
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    60. Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, Avdievich E, Hunton IC, Kolodner RD, Edelmann W, Wang JY. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q. Proc Natl Acad Sci U S A. 2008 Sep 16; 105(37):13993-8. PMID: 18768816.
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    61. Anderson JP, Mueller JL, Misaghi A, Anderson S, Sivagnanam M, Kolodner RD, Hoffman HM. Initial description of the human NLRP3 promoter. Genes Immun. 2008 Dec; 9(8):721-6. PMID: 18719602.
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    62. Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork NJ, Lavine JE, Taylor S, Newbury RO, Kolodner RD, Hoffman HM. Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology. 2008 Aug; 135(2):429-37. PMID: 18572020.
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    63. Iraqui I, Faye G, Ragu S, Masurel-Heneman A, Kolodner RD, Huang ME. Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae. Cancer Res. 2008 Feb 15; 68(4):1055-63. PMID: 18281480.
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    64. Kolodner RD, Mendillo ML, Putnam CD. Coupling distant sites in DNA during DNA mismatch repair. Proc Natl Acad Sci U S A. 2007 Aug 07; 104(32):12953-4. PMID: 17664420.
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    65. Harrington JM, Kolodner RD. Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs. Mol Cell Biol. 2007 Sep; 27(18):6546-54. PMID: 17636021.
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    66. Shell SS, Putnam CD, Kolodner RD. Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins. Proc Natl Acad Sci U S A. 2007 Jun 26; 104(26):10956-61. PMID: 17573527.
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    67. Ragu S, Faye G, Iraqui I, Masurel-Heneman A, Kolodner RD, Huang ME. Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death. Proc Natl Acad Sci U S A. 2007 Jun 05; 104(23):9747-52. PMID: 17535927.
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    68. Shell SS, Putnam CD, Kolodner RD. The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. Mol Cell. 2007 May 25; 26(4):565-78. PMID: 17531814.
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    69. Takahashi M, Shimodaira H, Andreutti-Zaugg C, Iggo R, Kolodner RD, Ishioka C. Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays. Cancer Res. 2007 May 15; 67(10):4595-604. PMID: 17510385.
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    70. Mendillo ML, Putnam CD, Kolodner RD. Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo. J Biol Chem. 2007 Jun 01; 282(22):16345-54. PMID: 17426027.
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    71. Aksentijevich I, Putnam CD, Remmers EF, Mueller JL, Le J, Kolodner RD, Moak Z, Chuang M, Austin F, Goldbach-Mansky R, Hoffman HM, Kastner DL. The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model. Arthritis Rheum. 2007 Apr; 56(4):1273-1285. PMID: 17393462.
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    72. Hu Y, Rolfs A, Bhullar B, Murthy TV, Zhu C, Berger MF, Camargo AA, Kelley F, McCarron S, Jepson D, Richardson A, Raphael J, Moreira D, Taycher E, Zuo D, Mohr S, Kane MF, Williamson J, Simpson A, Bulyk ML, Harlow E, Marsischky G, Kolodner RD, LaBaer J. Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Res. 2007 Apr; 17(4):536-43. PMID: 17322287.
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    73. Lagerstedt Robinson K, Liu T, Vandrovcova J, Halvarsson B, Clendenning M, Frebourg T, Papadopoulos N, Kinzler KW, Vogelstein B, Peltomäki P, Kolodner RD, Nilbert M, Lindblom A. Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics. J Natl Cancer Inst. 2007 Feb 21; 99(4):291-9. PMID: 17312306.
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    74. Vijayakumar S, Chapados BR, Schmidt KH, Kolodner RD, Tainer JA, Tomkinson AE. The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase. Nucleic Acids Res. 2007; 35(5):1624-37. PMID: 17308348.
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    75. Enserink JM, Smolka MB, Zhou H, Kolodner RD. Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae. J Cell Biol. 2006 Dec 04; 175(5):729-41. PMID: 17130284.
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    76. Smolka MB, Chen SH, Maddox PS, Enserink JM, Albuquerque CP, Wei XX, Desai A, Kolodner RD, Zhou H. An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. J Cell Biol. 2006 Dec 04; 175(5):743-53. PMID: 17130285.
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    77. Schmidt KH, Kolodner RD. Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants. Proc Natl Acad Sci U S A. 2006 Nov 28; 103(48):18196-201. PMID: 17114288.
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    78. Chen CC, Motegi A, Hasegawa Y, Myung K, Kolodner R, D'Andrea A. Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164 SUMOylation and ubiquitination. DNA Repair (Amst). 2006 Dec 09; 5(12):1475-88. PMID: 16990054.
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    79. Schmidt KH, Wu J, Kolodner RD. Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein. Mol Cell Biol. 2006 Jul; 26(14):5406-20. PMID: 16809776.
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    80. Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, Labaer J, Rochet JC, Bonini NM, Lindquist S. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science. 2006 Jul 21; 313(5785):324-8. PMID: 16794039.
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    81. Mazur DJ, Mendillo ML, Kolodner RD. Inhibition of Msh6 ATPase activity by mispaired DNA induces a Msh2(ATP)-Msh6(ATP) state capable of hydrolysis-independent movement along DNA. Mol Cell. 2006 Apr 07; 22(1):39-49. PMID: 16600868.
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    82. Pennaneach V, Putnam CD, Kolodner RD. Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae. Mol Microbiol. 2006 Mar; 59(5):1357-68. PMID: 16468981.
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    83. Kats ES, Albuquerque CP, Zhou H, Kolodner RD. Checkpoint functions are required for normal S-phase progression in Saccharomyces cerevisiae RCAF- and CAF-I-defective mutants. Proc Natl Acad Sci U S A. 2006 Mar 07; 103(10):3710-5. PMID: 16501045.
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    84. Hess MT, Mendillo ML, Mazur DJ, Kolodner RD. Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene. Proc Natl Acad Sci U S A. 2006 Jan 17; 103(3):558-63. PMID: 16407100.
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    88. Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nat Genet. 2005 Jul; 37(7):750-5. PMID: 15965476.
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    89. Smith S, Gupta A, Kolodner RD, Myung K. Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae. DNA Repair (Amst). 2005 May 02; 4(5):606-17. PMID: 15811632.
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    90. Mendillo ML, Mazur DJ, Kolodner RD. Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system. J Biol Chem. 2005 Jun 10; 280(23):22245-57. PMID: 15811858.
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    91. Huang ME, Kolodner RD. A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage. Mol Cell. 2005 Mar 04; 17(5):709-20. PMID: 15749020.
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    92. Sadler GR, Peterson M, Wasserman L, Mills P, Malcarne VL, Rock C, Ancoli-Israel S, Moore A, Weldon RN, Garcia T, Kolodner RD. Recruiting research participants at community education sites. J Cancer Educ. 2005; 20(4):235-9. PMID: 16497136.
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    93. Tajima A, Hess MT, Cabrera BL, Kolodner RD, Carethers JM. The mismatch repair complex hMutS alpha recognizes 5-fluorouracil-modified DNA: implications for chemosensitivity and resistance. Gastroenterology. 2004 Dec; 127(6):1678-84. PMID: 15578504.
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    94. Myung K, Smith S, Kolodner RD. Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2004 Nov 09; 101(45):15980-5. PMID: 15514023.
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    95. Putnam CD, Pennaneach V, Kolodner RD. Chromosome healing through terminal deletions generated by de novo telomere additions in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2004 Sep 07; 101(36):13262-7. PMID: 15328403.
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    96. Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell. 2004 Aug; 6(2):139-50. PMID: 15324697.
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    97. Pennaneach V, Kolodner RD. Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast. Nat Genet. 2004 Jun; 36(6):612-7. PMID: 15133512.
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    98. Tornaletti S, Maeda LS, Kolodner RD, Hanawalt PC. Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II. DNA Repair (Amst). 2004 May 04; 3(5):483-94. PMID: 15084310.
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    99. Mazina OM, Mazin AV, Nakagawa T, Kolodner RD, Kowalczykowski SC. Saccharomyces cerevisiae Mer3 helicase stimulates 3'-5' heteroduplex extension by Rad51; implications for crossover control in meiotic recombination. Cell. 2004 Apr 02; 117(1):47-56. PMID: 15066281.
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    100. Schmidt KH, Kolodner RD. Requirement of Rrm3 helicase for repair of spontaneous DNA lesions in cells lacking Srs2 or Sgs1 helicase. Mol Cell Biol. 2004 Apr; 24(8):3213-26. PMID: 15060145.
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    101. Bandipalliam P, Garber J, Kolodner RD, Syngal S. Clinical presentation correlates with the type of mismatch repair gene involved in hereditary nonpolyposis colon cancer. Gastroenterology. 2004 Mar; 126(3):936-7. PMID: 14988860.
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    102. Gazzoli I, Kolodner RD. Regulation of the human MSH6 gene by the Sp1 transcription factor and alteration of promoter activity and expression by polymorphisms. Mol Cell Biol. 2003 Nov; 23(22):7992-8007. PMID: 14585961.
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    103. Huang ME, Rio AG, Nicolas A, Kolodner RD. A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11529-34. PMID: 12972632.
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    104. Myung K, Pennaneach V, Kats ES, Kolodner RD. Saccharomyces cerevisiae chromatin-assembly factors that act during DNA replication function in the maintenance of genome stability. Proc Natl Acad Sci U S A. 2003 May 27; 100(11):6640-5. PMID: 12750463.
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    105. Kantake N, Sugiyama T, Kolodner RD, Kowalczykowski SC. The recombination-deficient mutant RPA (rfa1-t11) is displaced slowly from single-stranded DNA by Rad51 protein. J Biol Chem. 2003 Jun 27; 278(26):23410-7. PMID: 12697761.
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    106. Myung K, Kolodner RD. Induction of genome instability by DNA damage in Saccharomyces cerevisiae. DNA Repair (Amst). 2003 Mar 01; 2(3):243-58. PMID: 12547388.
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    107. Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, Kolas NK, Russell R, Hou H, Kneitz B, Yang G, Kunkel TA, Kolodner RD, Cohen PE, Edelmann W. Inactivation of Exonuclease 1 in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility. Genes Dev. 2003 Mar 01; 17(5):603-14. PMID: 12629043.
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    108. Shimodaira H, Yoshioka-Yamashita A, Kolodner RD, Wang JY. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2420-5. PMID: 12601175.
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    109. Noirot P, Gupta RC, Radding CM, Kolodner RD. Hallmarks of homology recognition by RecA-like recombinases are exhibited by the unrelated Escherichia coli RecT protein. EMBO J. 2003 Jan 15; 22(2):324-34. PMID: 12514138.
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    110. Jagmohan-Changur S, Poikonen T, Vilkki S, Launonen V, Wikman F, Orntoft TF, Møller P, Vasen H, Tops C, Kolodner RD, Mecklin JP, Järvinen H, Bevan S, Houlston RS, Aaltonen LA, Fodde R, Wijnen J, Karhu A. EXO1 variants occur commonly in normal population: evidence against a role in hereditary nonpolyposis colorectal cancer. Cancer Res. 2003 Jan 01; 63(1):154-8. PMID: 12517792.
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    111. Hoffman HM, Gregory SG, Mueller JL, Tresierras M, Broide DH, Wanderer AA, Kolodner RD. Fine structure mapping of CIAS1: identification of an ancestral haplotype and a common FCAS mutation, L353P. Hum Genet. 2003 Feb; 112(2):209-16. PMID: 12522564.
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    112. Lau PJ, Kolodner RD. Transfer of the MSH2.MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA. J Biol Chem. 2003 Jan 03; 278(1):14-7. PMID: 12435741.
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    113. Lau PJ, Flores-Rozas H, Kolodner RD. Isolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair. Mol Cell Biol. 2002 Oct; 22(19):6669-80. PMID: 12215524.
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    114. Schmidt KH, Derry KL, Kolodner RD. Saccharomyces cerevisiae RRM3, a 5' to 3' DNA helicase, physically interacts with proliferating cell nuclear antigen. J Biol Chem. 2002 Nov 22; 277(47):45331-7. PMID: 12239216.
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    115. Kolodner RD, Putnam CD, Myung K. Maintenance of genome stability in Saccharomyces cerevisiae. Science. 2002 Jul 26; 297(5581):552-7. PMID: 12142524.
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    116. Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, Heyer J, Kane MF, Fan K, Russell R, Brown AM, Kneitz B, Edelmann W, Kolodner RD, Lipkin M, Kucherlapati R. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. Proc Natl Acad Sci U S A. 2002 Jul 23; 99(15):9924-9. PMID: 12119409.
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    117. Gazzoli I, Loda M, Garber J, Syngal S, Kolodner RD. A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Res. 2002 Jul 15; 62(14):3925-8. PMID: 12124320.
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    118. Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E. Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res. 2002 Jun 15; 62(12):3485-92. PMID: 12067992.
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    119. Soustelle C, Vedel M, Kolodner R, Nicolas A. Replication protein A is required for meiotic recombination in Saccharomyces cerevisiae. Genetics. 2002 Jun; 161(2):535-47. PMID: 12072452.
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    120. Nakagawa T, Kolodner RD. The MER3 DNA helicase catalyzes the unwinding of holliday junctions. J Biol Chem. 2002 Aug 02; 277(31):28019-24. PMID: 12039965.
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    121. Hess MT, Gupta RD, Kolodner RD. Dominant Saccharomyces cerevisiae msh6 mutations cause increased mispair binding and decreased dissociation from mispairs by Msh2-Msh6 in the presence of ATP. J Biol Chem. 2002 Jul 12; 277(28):25545-53. PMID: 11986324.
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    122. Nakagawa T, Kolodner RD. Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over. Mol Cell Biol. 2002 May; 22(10):3281-91. PMID: 11971962.
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    123. Myung K, Kolodner RD. Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 2002 Apr 02; 99(7):4500-7. PMID: 11917116.
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    124. Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Res. 2001 Nov 01; 61(21):7934-42. PMID: 11691815.
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    125. Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet. 2001 Nov; 29(3):301-5. PMID: 11687797.
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    126. Amin NS, Nguyen MN, Oh S, Kolodner RD. exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Mol Cell Biol. 2001 Aug; 21(15):5142-55. PMID: 11438669.
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    127. Myung K, Chen C, Kolodner RD. Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature. 2001 Jun 28; 411(6841):1073-6. PMID: 11429610.
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    128. Nakagawa T, Flores-Rozas H, Kolodner RD. The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem. 2001 Aug 24; 276(34):31487-93. PMID: 11376001.
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    129. Huang SC, Lavine JE, Boland PS, Newbury RO, Kolodner R, Pham TT, Arnold CN, Boland CR, Carethers JM. Germline characterization of early-aged onset of hereditary non-polyposis colorectal cancer. J Pediatr. 2001 May; 138(5):629-35. PMID: 11343035.
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    130. Myung K, Datta A, Kolodner RD. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell. 2001 Feb 09; 104(3):397-408. PMID: 11239397.
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    131. Myung K, Datta A, Chen C, Kolodner RD. SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nat Genet. 2001 Jan; 27(1):113-6. PMID: 11138010.
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    132. Flores-Rozas H, Clark D, Kolodner RD. Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex. Nat Genet. 2000 Nov; 26(3):375-8. PMID: 11062484.
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    133. Kolodner RD. Guarding against mutation. Nature. 2000 Oct 12; 407(6805):687, 689. PMID: 11048703.
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    135. Syngal S, Fox EA, Eng C, Kolodner RD, Garber JE. Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. J Med Genet. 2000 Sep; 37(9):641-5. PMID: 10978352.
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    136. Datta A, Schmeits JL, Amin NS, Lau PJ, Myung K, Kolodner RD. Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. Mol Cell. 2000 Sep; 6(3):593-603. PMID: 11030339.
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    137. Kneitz B, Cohen PE, Avdievich E, Zhu L, Kane MF, Hou H, Kolodner RD, Kucherlapati R, Pollard JW, Edelmann W. MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes Dev. 2000 May 01; 14(9):1085-97. PMID: 10809667.
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    138. Flores-Rozas H, Kolodner RD. Links between replication, recombination and genome instability in eukaryotes. Trends Biochem Sci. 2000 Apr; 25(4):196-200. PMID: 10754554.
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    139. Hoffman HM, Wright FA, Broide DH, Wanderer AA, Kolodner RD. Identification of a locus on chromosome 1q44 for familial cold urticaria. Am J Hum Genet. 2000 May; 66(5):1693-8. PMID: 10741953.
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    140. Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Res. 2000 Feb 15; 60(4):803-7. PMID: 10706084.
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    141. Wang JY, Kolodner RD. Keystone Symposia on Molecular and Cellular Biology: 'The molecular basis of cancer'. Organizers: Carol L. Prives and George F. Vande Woude, Taos, NM, 15-21 March 1999. Biochim Biophys Acta. 2000 Feb 14; 1470(1):R21-8. PMID: 10656992.
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    142. Das Gupta R, Kolodner RD. Novel dominant mutations in Saccharomyces cerevisiae MSH6. Nat Genet. 2000 Jan; 24(1):53-6. PMID: 10615127.
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    143. Merker JD, Datta A, Kolodner RD, Petes TD. The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. Genetics. 2000 Jan; 154(1):491-3. PMID: 10681182.
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    144. Nakagawa T, Datta A, Kolodner RD. Multiple functions of MutS- and MutL-related heterocomplexes. Proc Natl Acad Sci U S A. 1999 Dec 07; 96(25):14186-8. PMID: 10588673.
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    145. Chen C, Merrill BJ, Lau PJ, Holm C, Kolodner RD. Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair. Mol Cell Biol. 1999 Nov; 19(11):7801-15. PMID: 10523669.
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    146. Kolodner RD, Tytell JD, Schmeits JL, Kane MF, Gupta RD, Weger J, Wahlberg S, Fox EA, Peel D, Ziogas A, Garber JE, Syngal S, Anton-Culver H, Li FP. Germ-line msh6 mutations in colorectal cancer families. Cancer Res. 1999 Oct 15; 59(20):5068-74. PMID: 10537275.
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    147. Marsischky GT, Kolodner RD. Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA. J Biol Chem. 1999 Sep 17; 274(38):26668-82. PMID: 10480869.
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    148. Ni TT, Marsischky GT, Kolodner RD. MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Mol Cell. 1999 Sep; 4(3):439-44. PMID: 10518225.
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    149. Chen C, Kolodner RD. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants. Nat Genet. 1999 Sep; 23(1):81-5. PMID: 10471504.
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    150. Verma L, Kane MF, Brassett C, Schmeits J, Evans DG, Kolodner RD, Maher ER. Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer. J Med Genet. 1999 Sep; 36(9):678-82. PMID: 10507723.
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    151. Syngal S, Fox EA, Li C, Dovidio M, Eng C, Kolodner RD, Garber JE. Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. JAMA. 1999 Jul 21; 282(3):247-53. PMID: 10422993.
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    152. Marsischky GT, Lee S, Griffith J, Kolodner RD. 'Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes. J Biol Chem. 1999 Mar 12; 274(11):7200-6. PMID: 10066781.
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    153. Froggatt NJ, Green J, Brassett C, Evans DG, Bishop DT, Kolodner R, Maher ER. A common MSH2 mutation in English and North American HNPCC families: origin, phenotypic expression, and sex specific differences in colorectal cancer. J Med Genet. 1999 Feb; 36(2):97-102. PMID: 10051005.
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    154. Kolodner RD, Marsischky GT. Eukaryotic DNA mismatch repair. Curr Opin Genet Dev. 1999 Feb; 9(1):89-96. PMID: 10072354.
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    155. Edelmann W, Cohen PE, Kneitz B, Winand N, Lia M, Heyer J, Kolodner R, Pollard JW, Kucherlapati R. Mammalian MutS homologue 5 is required for chromosome pairing in meiosis. Nat Genet. 1999 Jan; 21(1):123-7. PMID: 9916805.
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    156. Bertrand P, Tishkoff DX, Filosi N, Dasgupta R, Kolodner RD. Physical interaction between components of DNA mismatch repair and nucleotide excision repair. Proc Natl Acad Sci U S A. 1998 Nov 24; 95(24):14278-83. PMID: 9826691.
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    157. Tishkoff DX, Amin NS, Viars CS, Arden KC, Kolodner RD. Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. Cancer Res. 1998 Nov 15; 58(22):5027-31. PMID: 9823303.
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    158. Flores-Rozas H, Kolodner RD. The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations. Proc Natl Acad Sci U S A. 1998 Oct 13; 95(21):12404-9. PMID: 9770499.
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    159. Winand NJ, Panzer JA, Kolodner RD. Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. Genomics. 1998 Oct 01; 53(1):69-80. PMID: 9787078.
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    160. Page AM, Davis K, Molineux C, Kolodner RD, Johnson AW. Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae. Nucleic Acids Res. 1998 Aug 15; 26(16):3707-16. PMID: 9685486.
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    161. Lee SE, Moore JK, Holmes A, Umezu K, Kolodner RD, Haber JE. Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell. 1998 Aug 07; 94(3):399-409. PMID: 9708741.
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    162. Shimodaira H, Filosi N, Shibata H, Suzuki T, Radice P, Kanamaru R, Friend SH, Kolodner RD, Ishioka C. Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae. Nat Genet. 1998 Aug; 19(4):384-9. PMID: 9697702.
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    163. Chen C, Umezu K, Kolodner RD. Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair. Mol Cell. 1998 Jul; 2(1):9-22. PMID: 9702187.
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    164. Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma. Proc Natl Acad Sci U S A. 1998 Jun 09; 95(12):6870-5. PMID: 9618505.
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    165. Noirot P, Kolodner RD. DNA strand invasion promoted by Escherichia coli RecT protein. J Biol Chem. 1998 May 15; 273(20):12274-80. PMID: 9575178.
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    166. Umezu K, Sugawara N, Chen C, Haber JE, Kolodner RD. Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics. 1998 Mar; 148(3):989-1005. PMID: 9539419.
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    167. Lin YL, Shivji MK, Chen C, Kolodner R, Wood RD, Dutta A. The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair. J Biol Chem. 1998 Jan 16; 273(3):1453-61. PMID: 9430682.
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    168. Smith WM, Van Orsouw NJ, Fox EA, Kolodner RD, Vijg J, Eng C. Accurate, high-throughput "snapshot" detection of hMLH1 mutations by two-dimensional DNA electrophoresis. Genet Test. 1998; 2(1):43-53. PMID: 10464596.
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    169. Edelmann W, Yang K, Umar A, Heyer J, Lau K, Fan K, Liedtke W, Cohen PE, Kane MF, Lipford JR, Yu N, Crouse GF, Pollard JW, Kunkel T, Lipkin M, Kolodner R, Kucherlapati R. Mutation in the mismatch repair gene Msh6 causes cancer susceptibility. Cell. 1997 Nov 14; 91(4):467-77. PMID: 9390556.
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    170. Hackman P, Tannergård P, Osei-Mensa S, Chen J, Kane MF, Kolodner R, Lambert B, Hellgren D, Lindblom A. A human compound heterozygote for two MLH1 missense mutations. Nat Genet. 1997 Oct; 17(2):135-6. PMID: 9326924.
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    171. Umar A, Koi M, Risinger JI, Glaab WE, Tindall KR, Kolodner RD, Boland CR, Barrett JC, Kunkel TA. Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6. Cancer Res. 1997 Sep 15; 57(18):3949-55. PMID: 9307278.
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    172. Tishkoff DX, Boerger AL, Bertrand P, Filosi N, Gaida GM, Kane MF, Kolodner RD. Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proc Natl Acad Sci U S A. 1997 Jul 08; 94(14):7487-92. PMID: 9207118.
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    173. Fiorentini P, Huang KN, Tishkoff DX, Kolodner RD, Symington LS. Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Mol Cell Biol. 1997 May; 17(5):2764-73. PMID: 9111347.
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    174. Kane MF, Loda M, Gaida GM, Lipman J, Mishra R, Goldman H, Jessup JM, Kolodner R. Methylation of the hMLH1 promoter correlates with lack of expression of hMLH1 in sporadic colon tumors and mismatch repair-defective human tumor cell lines. Cancer Res. 1997 Mar 01; 57(5):808-11. PMID: 9041175.
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    175. Wahlberg SS, Nyström-Lahti M, Kane MF, Kolodner RD, Peltomäki P, Lindblom A. Low frequency of hMSH2 mutations in Swedish HNPCC families. Int J Cancer. 1997 Feb 20; 74(1):134-7. PMID: 9036882.
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    176. Tishkoff DX, Filosi N, Gaida GM, Kolodner RD. A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair. Cell. 1997 Jan 24; 88(2):253-63. PMID: 9008166.
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    177. Alani E, Lee S, Kane MF, Griffith J, Kolodner RD. Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes Holliday junctions in DNA. J Mol Biol. 1997 Jan 24; 265(3):289-301. PMID: 9018043.
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    178. Acharya S, Wilson T, Gradia S, Kane MF, Guerrette S, Marsischky GT, Kolodner R, Fishel R. hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6. Proc Natl Acad Sci U S A. 1996 Nov 26; 93(24):13629-34. PMID: 8942985.
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    179. Tonin P, Weber B, Offit K, Couch F, Rebbeck TR, Neuhausen S, Godwin AK, Daly M, Wagner-Costalos J, Berman D, Grana G, Fox E, Kane MF, Kolodner RD, Krainer M, Haber DA, Struewing JP, Warner E, Rosen B, Lerman C, Peshkin B, Norton L, Serova O, Foulkes WD, Garber JE. Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families. Nat Med. 1996 Nov; 2(11):1179-83. PMID: 8898735.
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    180. Edelmann W, Cohen PE, Kane M, Lau K, Morrow B, Bennett S, Umar A, Kunkel T, Cattoretti G, Chaganti R, Pollard JW, Kolodner RD, Kucherlapati R. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 1996 Jun 28; 85(7):1125-34. PMID: 8674118.
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    181. Kolodner R. Biochemistry and genetics of eukaryotic mismatch repair. Genes Dev. 1996 Jun 15; 10(12):1433-42. PMID: 8666228.
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    182. Jeyaprakash A, Das Gupta R, Kolodner R. Saccharomyces cerevisiae pms2 mutations are alleles of MLH1, and pms2-2 corresponds to a hereditary nonpolyposis colorectal carcinoma-causing missense mutation. Mol Cell Biol. 1996 Jun; 16(6):3008-11. PMID: 8649412.
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    183. Marsischky GT, Filosi N, Kane MF, Kolodner R. Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair. Genes Dev. 1996 Feb 15; 10(4):407-20. PMID: 8600025.
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    184. Wijnen J, Khan PM, Vasen H, Menko F, van der Klift H, van den Broek M, van Leeuwen-Cornelisse I, Nagengast F, Meijers-Heijboer EJ, Lindhout D, Griffioen G, Cats A, Kleibeuker J, Varesco L, Bertario L, Bisgaard ML, Mohr J, Kolodner R, Fodde R. Majority of hMLH1 mutations responsible for hereditary nonpolyposis colorectal cancer cluster at the exonic region 15-16. Am J Hum Genet. 1996 Feb; 58(2):300-7. PMID: 8571956.
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    185. Boyer JC, Umar A, Risinger JI, Lipford JR, Kane M, Yin S, Barrett JC, Kolodner RD, Kunkel TA. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines. Cancer Res. 1995 Dec 15; 55(24):6063-70. PMID: 8521394.
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    186. Tannergård P, Lipford JR, Kolodner R, Frödin JE, Nordenskjöld M, Lindblom A. Mutation screening in the hMLH1 gene in Swedish hereditary nonpolyposis colon cancer families. Cancer Res. 1995 Dec 15; 55(24):6092-6. PMID: 8521398.
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    187. Thresher RJ, Makhov AM, Hall SD, Kolodner R, Griffith JD. Electron microscopic visualization of RecT protein and its complexes with DNA. J Mol Biol. 1995 Dec 01; 254(3):364-71. PMID: 7490755.
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    188. Børresen AL, Lothe RA, Meling GI, Lystad S, Morrison P, Lipford J, Kane MF, Rognum TO, Kolodner RD. Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas. Hum Mol Genet. 1995 Nov; 4(11):2065-72. PMID: 8589682.
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    189. Kolodner RD. Mismatch repair: mechanisms and relationship to cancer susceptibility. Trends Biochem Sci. 1995 Oct; 20(10):397-401. PMID: 8533151.
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    190. Fishel R, Kolodner RD. Identification of mismatch repair genes and their role in the development of cancer. Curr Opin Genet Dev. 1995 Jun; 5(3):382-95. PMID: 7549435.
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    191. Johnson AW, Kolodner RD. Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control. Mol Cell Biol. 1995 May; 15(5):2719-27. PMID: 7739552.
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    192. Heyer WD, Johnson AW, Reinhart U, Kolodner RD. Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease. Mol Cell Biol. 1995 May; 15(5):2728-36. PMID: 7739553.
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    193. Tishkoff DX, Rockmill B, Roeder GS, Kolodner RD. The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics. 1995 Feb; 139(2):495-509. PMID: 7713413.
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    194. Kolodner RD, Hall NR, Lipford J, Kane MF, Morrison PT, Finan PJ, Burn J, Chapman P, Earabino C, Merchant E. Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations. Cancer Res. 1995 Jan 15; 55(2):242-8. PMID: 7812952.
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    195. Alani E, Chi NW, Kolodner R. The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions. Genes Dev. 1995 Jan 15; 9(2):234-47. PMID: 7851796.
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    196. Kolodner RD, Alani E. Mismatch repair and cancer susceptibility. Curr Opin Biotechnol. 1994 Dec; 5(6):585-94. PMID: 7765740.
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    197. Kolodner RD, Hall NR, Lipford J, Kane MF, Rao MR, Morrison P, Wirth L, Finan PJ, Burn J, Chapman P. Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations. Genomics. 1994 Dec; 24(3):516-26. PMID: 7713503.
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    198. Chi NW, Kolodner RD. Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches. J Biol Chem. 1994 Nov 25; 269(47):29984-92. PMID: 7961998.
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    199. Chi NW, Kolodner RD. The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches. J Biol Chem. 1994 Nov 25; 269(47):29993-7. PMID: 7961999.
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    200. Umezu K, Kolodner RD. Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein. J Biol Chem. 1994 Nov 25; 269(47):30005-13. PMID: 7962001.
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    201. Mary JL, Bishop T, Kolodner R, Lipford JR, Kane M, Weber W, Torhorst J, Müller H, Spycher M, Scott RJ. Mutational analysis of the hMSH2 gene reveals a three base pair deletion in a family predisposed to colorectal cancer development. Hum Mol Genet. 1994 Nov; 3(11):2067-9. PMID: 7874129.
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    202. Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science. 1994 Aug 19; 265(5175):1091-3. PMID: 8066446.
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    203. Alani E, Reenan RA, Kolodner RD. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics. 1994 May; 137(1):19-39. PMID: 8056309.
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    204. Hall SD, Kolodner RD. Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3205-9. PMID: 8159725.
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    205. Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 1994 Apr 08; 77(1):1 p following 166. PMID: 8156592.
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    206. Luisi-DeLuca C, Kolodner R. Purification and characterization of the Escherichia coli RecO protein. Renaturation of complementary single-stranded DNA molecules catalyzed by the RecO protein. J Mol Biol. 1994 Feb 11; 236(1):124-38. PMID: 8107098.
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    207. Johnson AW, Kolodner RD. The activity of the Saccharomyces cerevisiae strand exchange protein 1 intrinsic exonuclease during joint molecule formation. J Biol Chem. 1994 Feb 04; 269(5):3664-72. PMID: 8106411.
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    208. Johnon AW, Kolodner RD. Characterization of the interaction of Saccharomyces cerevisiae strand exchange protein 1 with DNA. J Biol Chem. 1994 Feb 04; 269(5):3673-81. PMID: 8106412.
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    209. Kolodner R, Hall SD, Luisi-DeLuca C. Homologous pairing proteins encoded by the Escherichia coli recE and recT genes. Mol Microbiol. 1994 Jan; 11(1):23-30. PMID: 8145642.
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    210. Hall NR, Taylor GR, Finan PJ, Kolodner RD, Bodmer WF, Cottrell SE, Frayling I, Bishop DT. Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. Eur J Cancer. 1994; 30A(10):1550-2. PMID: 7833117.
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    211. Kolodner RD, Hall NR, Lipford J, Kane MF, Rao MR, Morrison P, Wirth L, Finan PJ, Burn J, Chapman P. Human mismatch repair genes and their association with hereditary non-polyposis colon cancer. Cold Spring Harb Symp Quant Biol. 1994; 59:331-8. PMID: 7587085.
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    212. Lincoln MJ, Weir C, Moreshead G, Kolodner R, Williamson J. Creating and evaluating the Department of Veterans Affairs electronic medical record and national clinical lexicon. Proc Annu Symp Comput Appl Med Care. 1994; 1047. PMID: 7949885.
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    213. Fishel R, Lescoe MK, Rao MR, Copeland NG, Jenkins NA, Garber J, Kane M, Kolodner R. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer. Cell. 1993 Dec 03; 75(5):1027-38. PMID: 8252616.
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    214. Umezu K, Chi NW, Kolodner RD. Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):3875-9. PMID: 8483906.
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    215. Hall SD, Kane MF, Kolodner RD. Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA. J Bacteriol. 1993 Jan; 175(1):277-87. PMID: 8416902.
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    216. Heyer WD, Kolodner RD. Enzymology of homologous recombination in Saccharomyces cerevisiae. Prog Nucleic Acid Res Mol Biol. 1993; 46:221-71. PMID: 8234785.
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    217. Reenan RA, Kolodner RD. Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics. 1992 Dec; 132(4):963-73. PMID: 1459447.
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    218. Reenan RA, Kolodner RD. Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics. 1992 Dec; 132(4):975-85. PMID: 1334021.
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    219. West AB, Roberts TM, Kolodner RD. Regulation of the reverse transcriptase of human immunodeficiency virus type 1 by dNTPs. Proc Natl Acad Sci U S A. 1992 Oct 15; 89(20):9720-4. PMID: 1384060.
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    220. Alani E, Thresher R, Griffith JD, Kolodner RD. Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein. J Mol Biol. 1992 Sep 05; 227(1):54-71. PMID: 1522601.
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    221. Luisi-DeLuca C, Kolodner RD. Effect of terminal non-homology on intramolecular recombination of linear plasmid substrates in Escherichia coli. J Mol Biol. 1992 Sep 05; 227(1):72-80. PMID: 1522602.
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    222. Johnson AW, Kolodner RD. Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activities. J Biol Chem. 1991 Jul 25; 266(21):14046-54. PMID: 1856231.
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    223. Erdile LF, Heyer WD, Kolodner R, Kelly TJ. Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication. J Biol Chem. 1991 Jun 25; 266(18):12090-8. PMID: 2050703.
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    224. Tishkoff DX, Johnson AW, Kolodner RD. Molecular and genetic analysis of the gene encoding the Saccharomyces cerevisiae strand exchange protein Sep1. Mol Cell Biol. 1991 May; 11(5):2593-608. PMID: 1840632.
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    225. Heyer WD, Johnson AW, Norris DN, Tishkoff D, Kolodner RD. Saccharomyces cerevisiae proteins involved in hybrid DNA formation in vitro. Biochimie. 1991 Feb-Mar; 73(2-3):269-76. PMID: 1883885.
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    226. Lovett ST, Kolodner RD. Nucleotide sequence of the Escherichia coli recJ chromosomal region and construction of recJ-overexpression plasmids. J Bacteriol. 1991 Jan; 173(1):353-64. PMID: 1987126.
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    227. Griffin TJ, Kolodner RD. Purification and preliminary characterization of the Escherichia coli K-12 recF protein. J Bacteriol. 1990 Nov; 172(11):6291-9. PMID: 2228960.
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    228. Norris D, Kolodner R. Purification of a strand exchange stimulatory factor from Saccharomyces cerevisiae. Biochemistry. 1990 Aug 28; 29(34):7903-11. PMID: 2261445.
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    229. Norris D, Kolodner R. Interaction of a Saccharomyces cerevisiae strand exchange stimulatory factor with DNA. Biochemistry. 1990 Aug 28; 29(34):7911-7. PMID: 2261446.
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    230. Heyer WD, Rao MR, Erdile LF, Kelly TJ, Kolodner RD. An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. EMBO J. 1990 Jul; 9(7):2321-9. PMID: 2192864.
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    231. Johnson RS, Sheng M, Greenberg ME, Kolodner RD, Papaioannou VE, Spiegelman BM. Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. Science. 1989 Sep 15; 245(4923):1234-6. PMID: 2506639.
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    232. Morrison PT, Lovett ST, Gilson LE, Kolodner R. Molecular analysis of the Escherichia coli recO gene. J Bacteriol. 1989 Jul; 171(7):3641-9. PMID: 2544549.
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    233. Luisi-DeLuca C, Lovett ST, Kolodner RD. Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants. Genetics. 1989 Jun; 122(2):269-78. PMID: 2670665.
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    234. Fishel R, Kolodner R. Gene conversion in Escherichia coli: the recF pathway for resolution of heteroduplex DNA. J Bacteriol. 1989 Jun; 171(6):3046-52. PMID: 2656639.
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    235. Bishop DK, Andersen J, Kolodner RD. Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA. Proc Natl Acad Sci U S A. 1989 May; 86(10):3713-7. PMID: 2498874.
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    236. Heyer WD, Kolodner RD. Purification and characterization of a protein from Saccharomyces cerevisiae that binds tightly to single-stranded DNA and stimulates a cognate strand exchange protein. Biochemistry. 1989 Apr 04; 28(7):2856-62. PMID: 2663063.
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    237. Lovett ST, Kolodner RD. Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli. Proc Natl Acad Sci U S A. 1989 Apr; 86(8):2627-31. PMID: 2649886.
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    238. Luisi-DeLuca C, Clark AJ, Kolodner RD. Analysis of the recE locus of Escherichia coli K-12 by use of polyclonal antibodies to exonuclease VIII. J Bacteriol. 1988 Dec; 170(12):5797-805. PMID: 3056915.
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    239. Heyer WD, Evans DH, Kolodner RD. Renaturation of DNA by a Saccharomyces cerevisiae protein that catalyzes homologous pairing and strand exchange. J Biol Chem. 1988 Oct 15; 263(29):15189-95. PMID: 3049603.
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    240. Lovett ST, Luisi-DeLuca C, Kolodner RD. The genetic dependence of recombination in recD mutants of Escherichia coli. Genetics. 1988 Sep; 120(1):37-45. PMID: 3065139.
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    241. Smith CL, Kolodner RD. Mapping of Escherichia coli chromosomal Tn5 and F insertions by pulsed field gel electrophoresis. Genetics. 1988 Jun; 119(2):227-36. PMID: 2840334.
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    242. Evans DH, Kolodner R. Effect of DNA structure and nucleotide sequence on Holliday junction resolution by a Saccharomyces cerevisiae endonuclease. J Mol Biol. 1988 May 05; 201(1):69-80. PMID: 2843646.
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    243. Kolodner R, Evans DH, Morrison PT. Purification and characterization of an activity from Saccharomyces cerevisiae that catalyzes homologous pairing and strand exchange. Proc Natl Acad Sci U S A. 1987 Aug; 84(16):5560-4. PMID: 3303029.
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    244. Evans DH, Kolodner R. Construction of a synthetic Holliday junction analog and characterization of its interaction with a Saccharomyces cerevisiae endonuclease that cleaves Holliday junctions. J Biol Chem. 1987 Jul 05; 262(19):9160-5. PMID: 3036850.
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    245. Bishop DK, Williamson MS, Fogel S, Kolodner RD. The role of heteroduplex correction in gene conversion in Saccharomyces cerevisiae. Nature. 1987 Jul 23-29; 328(6128):362-4. PMID: 3299108.
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    246. Muster-Nassal C, Kolodner R. Mismatch correction catalyzed by cell-free extracts of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1986 Oct; 83(20):7618-22. PMID: 3532118.
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    247. Bishop DK, Kolodner RD. Repair of heteroduplex plasmid DNA after transformation into Saccharomyces cerevisiae. Mol Cell Biol. 1986 Oct; 6(10):3401-9. PMID: 3025591.
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    248. Syvanen M, Hopkins JD, Griffin TJ, Liang TY, Ippen-Ihler K, Kolodner R. Stimulation of precise excision and recombination by conjugal proficient F'plasmids. Mol Gen Genet. 1986 Apr; 203(1):1-7. PMID: 2872578.
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    249. Fishel RA, Siegel EC, Kolodner R. Gene conversion in Escherichia coli. Resolution of heteroallelic mismatched nucleotides by co-repair. J Mol Biol. 1986 Mar 20; 188(2):147-57. PMID: 3522919.
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    250. Symington LS, Morrison P, Kolodner R. Intramolecular recombination of linear DNA catalyzed by the Escherichia coli RecE recombination system. J Mol Biol. 1985 Dec 05; 186(3):515-25. PMID: 3005590.
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    251. Symington LS, Kolodner R. Partial purification of an enzyme from Saccharomyces cerevisiae that cleaves Holliday junctions. Proc Natl Acad Sci U S A. 1985 Nov; 82(21):7247-51. PMID: 3903750.
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    252. Symington LS, Morrison P, Kolodner R. Plasmid recombination intermediates generated in a Saccharomyces cerevisiae cell-free recombination system. Mol Cell Biol. 1985 Sep; 5(9):2361-8. PMID: 3915541.
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    253. Kolodner R, Fishel RA, Howard M. Genetic recombination of bacterial plasmid DNA: effect of RecF pathway mutations on plasmid recombination in Escherichia coli. J Bacteriol. 1985 Sep; 163(3):1060-6. PMID: 2993230.
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    254. Fishel RA, Kolodner R. Escherichia coli strains containing mutations in the structural gene for topoisomerase I are recombination deficient. J Bacteriol. 1984 Dec; 160(3):1168-70. PMID: 6094504.
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    255. Fishel RA, Kolodner R. An Escherichia coli cell-free system that catalyzes the repair of symmetrically methylated heteroduplex DNA. Cold Spring Harb Symp Quant Biol. 1984; 49:603-9. PMID: 6397315.
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    256. Symington LS, Morrison PT, Kolodner R. Genetic recombination catalyzed by cell-free extracts of Saccharomyces cerevisiae. Cold Spring Harb Symp Quant Biol. 1984; 49:805-14. PMID: 6397323.
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    257. Symington LS, Fogarty LM, Kolodner R. Genetic recombination of homologous plasmids catalyzed by cell-free extracts of Saccharomyces cerevisiae. Cell. 1983 Dec; 35(3 Pt 2):805-13. PMID: 6360380.
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    258. Joseph JW, Kolodner R. Exonuclease VIII of Escherichia coli. I. Purification and physical properties. J Biol Chem. 1983 Sep 10; 258(17):10411-7. PMID: 6350289.
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    259. Joseph JW, Kolodner R. Exonuclease VIII of Escherichia coli. II. Mechanism of action. J Biol Chem. 1983 Sep 10; 258(17):10418-24. PMID: 6309804.
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    260. Doherty MJ, Morrison PT, Kolodner R. Genetic recombination of bacterial plasmid DNA. Physical and genetic analysis of the products of plasmid recombination in Escherichia coli. J Mol Biol. 1983 Jul 05; 167(3):539-60. PMID: 6308264.
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    261. James AA, Morrison PT, Kolodner R. Isolation of genetic elements that increase frequencies of plasmid recombinants. Nature. 1983 May 19-25; 303(5914):256-9. PMID: 6341860.
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    262. James AA, Morrison PT, Kolodner R. Genetic recombination of bacterial plasmid DNA. Analysis of the effect of recombination-deficient mutations on plasmid recombination. J Mol Biol. 1982 Sep 25; 160(3):411-30. PMID: 6759658.
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    263. Fishel RA, James AA, Kolodner R. recA-independent general genetic recombination of plasmids. Nature. 1981 Nov 12; 294(5837):184-6. PMID: 7029308.
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    264. Kolodner R. Genetic recombination of bacterial plasmid DNA: electron microscopic analysis of in vitro intramolecular recombination. Proc Natl Acad Sci U S A. 1980 Aug; 77(8):4847-51. PMID: 6254041.
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    265. Perler F, Efstratiadis A, Lomedico P, Gilbert W, Kolodner R, Dodgson J. The evolution of genes: the chicken preproinsulin gene. Cell. 1980 Jun; 20(2):555-66. PMID: 7388949.
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    266. Lomedico P, Rosenthal N, Efstratidadis A, Gilbert W, Kolodner R, Tizard R. The structure and evolution of the two nonallelic rat preproinsulin genes. Cell. 1979 Oct; 18(2):545-58. PMID: 498284.
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    267. Richardson CC, Romano LJ, Kolodner R, LeClerc JE, Tamanoi F, Engler MJ, Dean FB, Richardson DS. Replication of bacteriophage T7 DNA by purified proteins. Cold Spring Harb Symp Quant Biol. 1979; 43 Pt 1:427-40. PMID: 225112.
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    268. Kolodner R, Masamune Y, LeClerc JE, Richardson CC. Gene 4 protein of bacteriophage T7. Purification physical properties, and stimulation of T7 DNA polymerase during the elongation of polynucleotide chains. J Biol Chem. 1978 Jan 25; 253(2):566-73. PMID: 338611.
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    269. Kolodner R, Richardson CC. Gene 4 protein of bacteriophage T7. Characterization of the product synthesized by the T7 DNA polymerase and gene 4 protein in the absence of ribonucleoside 5'-triphosphates. J Biol Chem. 1978 Jan 25; 253(2):574-84. PMID: 618886.
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    270. Bedbrook JR, Kolodner R, Bogorad L. Zea mays chloroplast ribosomal RNA genes are part of a 22,000 base pair inverted repeat. Cell. 1977 Aug; 11(4):739-49. PMID: 890739.
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    271. Kolodner R, Richardson CC. Replication of duplex DNA by bacteriophage T7 DNA polymerase and gene 4 protein is accompanied by hydrolysis of nucleoside 5'-triphosphates. Proc Natl Acad Sci U S A. 1977 Apr; 74(4):1525-9. PMID: 323856.
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    272. Kolodner R, Tewari KK, Warner RC. Physical studies on the size and structure of the covalently closed circular chloroplast DNA from higher plants. Biochim Biophys Acta. 1976 Oct 04; 447(2):144-55. PMID: 10002.
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    273. Kolodner R, Tewari KK. The molecular size and conformation of the chloroplast DNA from higher plants. Biochim Biophys Acta. 1975 Sep 01; 402(3):372-90. PMID: 1164522.
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    274. Kolodner RD, Tewari KK. Chloroplast DNA from higher plants replicates by both the Cairns and the rolling circle mechanism. Nature. 1975 Aug 28; 256(5520):708-11. PMID: 1153007.
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