Frank Furnari
|
Title(s) | Professor, Pathology |
---|
School | Vc-health Sciences-schools |
---|
Address | 9500 Gilman Drive # La Jolla CA 92093
|
---|
vCard | Download vCard |
---|
|
|
Research Bibliographic
Altmetrics Details
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media.
(Note that publications are often cited in additional ways that are not shown here.)
Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication.
Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.)
Click a Field or Translation tag to filter the publications.
-
Mechanisms of stearoyl CoA desaturase inhibitor sensitivity and acquired resistance in cancer. Sci Adv. 2021 Feb; 7(7).
PMID: 33568479.
View in: PubMed Mentions: Fields:
-
Pten Deficiency Leads To Proteasome Addiction, A Novel Vulnerability In Glioblastoma. Neuro Oncol. 2021 Jan 11.
Benitez JA, Finlay D, Castanza A, Parisian AD, Ma J, Longobardi C, Campos A, Vadla R, Izurieta A, Scerra G, Koga T, Long T, Chavez L, Mesirov JP, Vuori K, Furnari F. PMID: 33428749.
View in: PubMed Mentions: Fields:
-
EGFRvIII uses intrinsic and extrinsic mechanisms to reduce glioma adhesion and increase migration. J Cell Sci. 2020 Nov 26.
Banisadr A, Eick M, Beri P, Parisian AD, Yeoman B, Placone JK, Engler AJ, Furnari F. PMID: 33243756.
View in: PubMed Mentions: Fields:
-
SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability. Genes Dev. 2020 Oct 01; 34(19-20):1316-1329.
Parisian AD, Koga T, Miki S, Johann PD, Kool M, Crawford JR, Furnari FB. PMID: 32912900.
View in: PubMed Mentions: Fields:
-
Epidermal Growth Factor Receptor (EGFR) as a molecular determinant of glioblastoma response to dopamine receptor 2 (DRD2) inhibitors. Neuro Oncol. 2020 Aug 24.
He Y, Li J, Koga T, Ma J, Dhawan S, Suzuki Y, Furnari F, Prabhu VV, Allen JE, Chen CC. PMID: 32830856.
View in: PubMed Mentions: Fields:
-
Genome Engineering Evolves Brain Tumor Modeling. Neurol Med Chir (Tokyo). 2020 Jul 15; 60(7):329-336.
Koga T, Chen CC, Furnari FB. PMID: 32536682.
View in: PubMed Mentions: 1 Fields:
-
Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas. EBioMedicine. 2020 May; 55:102736.
Ramakrishnan V, Xu B, Akers J, Nguyen T, Ma J, Dhawan S, Ning J, Mao Y, Hua W, Kokkoli E, Furnari F, Carter BS, Chen CC. PMID: 32361246.
View in: PubMed Mentions: 1 Fields:
-
Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nat Commun. 2020 04 20; 11(1):1958.
Koga T, Chaim IA, Benitez JA, Markmiller S, Parisian AD, Hevner RF, Turner KM, Hessenauer FM, D'Antonio M, Nguyen ND, Saberi S, Ma J, Miki S, Boyer AD, Ravits J, Frazer KA, Bafna V, Chen CC, Mischel PS, Yeo GW, Furnari FB. PMID: 32312984.
View in: PubMed Mentions: Fields:
-
Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells. Nat Commun. 2020 Jan 28; 11(1):550.
Koga T, Chaim IA, Benitez JA, Markmiller S, Parisian AD, Hevner RF, Turner KM, Hessenauer FM, D'Antonio M, Nguyen ND, Saberi S, Ma J, Miki S, Boyer AD, Ravits J, Frazer KA, Bafna V, Chen CC, Mischel PS, Yeo GW, Furnari FB. PMID: 31992716.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
-
Integrin avß5 Internalizes Zika Virus during Neural Stem Cells Infection and Provides a Promising Target for Antiviral Therapy. Cell Rep. 2020 01 28; 30(4):969-983.e4.
Wang S, Zhang Q, Tiwari SK, Lichinchi G, Yau EH, Hui H, Li W, Furnari F, Rana TM. PMID: 31956073.
View in: PubMed Mentions: 6 Fields:
-
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 Dec 09; 36(6):690-691.
Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 31821785.
View in: PubMed Mentions: 3 Fields:
-
Circular ecDNA promotes accessible chromatin and high oncogene expression. Nature. 2019 11; 575(7784):699-703.
Wu S, Turner KM, Nguyen N, Raviram R, Erb M, Santini J, Luebeck J, Rajkumar U, Diao Y, Li B, Zhang W, Jameson N, Corces MR, Granja JM, Chen X, Coruh C, Abnousi A, Houston J, Ye Z, Hu R, Yu M, Kim H, Law JA, Verhaak RGW, Hu M, Furnari FB, Chang HY, Ren B, Bafna V, Mischel PS. PMID: 31748743.
View in: PubMed Mentions: 20 Fields: Translation: HumansCells
-
Intron 1-Mediated Regulation of EGFR Expression in EGFR-Dependent Malignancies Is Mediated by AP-1 and BET Proteins. Mol Cancer Res. 2019 11; 17(11):2208-2220.
Jameson NM, Ma J, Benitez J, Izurieta A, Han JY, Mendez R, Parisian A, Furnari F. PMID: 31444232.
View in: PubMed Mentions: Fields: Translation: HumansCells
-
Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling. Cell Metab. 2019 09 03; 30(3):525-538.e8.
Bi J, Ichu TA, Zanca C, Yang H, Zhang W, Gu Y, Chowdhry S, Reed A, Ikegami S, Turner KM, Zhang W, Villa GR, Wu S, Quehenberger O, Yong WH, Kornblum HI, Rich JN, Cloughesy TF, Cavenee WK, Furnari FB, Cravatt BF, Mischel PS. PMID: 31303424.
View in: PubMed Mentions: 8 Fields: Translation: HumansAnimalsCells
-
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 May 13; 35(5):816.
Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 31085179.
View in: PubMed Mentions: 6 Fields:
-
Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope. Proc Natl Acad Sci U S A. 2019 05 14; 116(20):10009-10018.
Orellana L, Thorne AH, Lema R, Gustavsson J, Parisian AD, Hospital A, Cordeiro TN, Bernadó P, Scott AM, Brun-Heath I, Lindahl E, Cavenee WK, Furnari FB, Orozco M. PMID: 31028138.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
-
NAD metabolic dependency in cancer is shaped by gene amplification and enhancer remodelling. Nature. 2019 05; 569(7757):570-575.
Chowdhry S, Zanca C, Rajkumar U, Koga T, Diao Y, Raviram R, Liu F, Turner K, Yang H, Brunk E, Bi J, Furnari F, Bafna V, Ren B, Mischel PS. PMID: 31019297.
View in: PubMed Mentions: 23 Fields: Translation: HumansAnimalsCells
-
When less is more: Gaining power through gene rearrangement of amplified EGFR. Oncotarget. 2019 Mar 15; 10(22):2116-2117.
Koga T, Chen CC, Furnari FB. PMID: 31040904.
View in: PubMed Mentions: Fields:
-
Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 03 18; 35(3):504-518.e7.
Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 30827889.
View in: PubMed Mentions: 12 Fields: Translation: HumansAnimalsCells
-
Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk. Cancer Res. 2019 03 15; 79(6):1239-1251.
Sun T, Patil R, Galstyan A, Klymyshyn D, Ding H, Chesnokova A, Cavenee WK, Furnari FB, Ljubimov VA, Shatalova ES, Wagner S, Li D, Mamelak AN, Bannykh SI, Patil CG, Rudnick JD, Hu J, Grodzinski ZB, Rekechenetskiy A, Falahatian V, Lyubimov AV, Chen YL, Leoh LS, Daniels-Wells TR, Penichet ML, Holler E, Ljubimov AV, Black KL, Ljubimova JY. PMID: 30659021.
View in: PubMed Mentions: 9 Fields: Translation: HumansAnimalsCells
-
Mapping of genomic EGFRvIII deletions in glioblastoma: insight into rearrangement mechanisms and biomarker development. Neuro Oncol. 2018 09 03; 20(10):1310-1320.
Koga T, Li B, Figueroa JM, Ren B, Chen CC, Carter BS, Furnari FB. PMID: 29660021.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
-
Regulation of protective autophagy in anoikis-resistant glioma stem cells by SDCBP/MDA-9/Syntenin. Autophagy. 2018; 14(10):1845-1846.
Talukdar S, Pradhan AK, Bhoopathi P, Shen XN, August LA, Windle JJ, Sarkar D, Furnari FB, Cavenee WK, Das SK, Emdad L, Fisher PB. PMID: 30118375.
View in: PubMed Mentions: 8 Fields: Translation: HumansCells
-
Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development. Cancer Cell. 2018 07 09; 34(1):163-177.e7.
Binder ZA, Thorne AH, Bakas S, Wileyto EP, Bilello M, Akbari H, Rathore S, Ha SM, Zhang L, Ferguson CJ, Dahiya S, Bi WL, Reardon DA, Idbaih A, Felsberg J, Hentschel B, Weller M, Bagley SJ, Morrissette JJD, Nasrallah MP, Ma J, Zanca C, Scott AM, Orellana L, Davatzikos C, Furnari FB, O'Rourke DM. PMID: 29990498.
View in: PubMed Mentions: 23 Fields: Translation: HumansAnimalsCells
-
YAP and MRTF-A, transcriptional co-activators of RhoA-mediated gene expression, are critical for glioblastoma tumorigenicity. Oncogene. 2018 10; 37(41):5492-5507.
Yu OM, Benitez JA, Plouffe SW, Ryback D, Klein A, Smith J, Greenbaum J, Delatte B, Rao A, Guan KL, Furnari FB, Chaim OM, Miyamoto S, Brown JH. PMID: 29887596.
View in: PubMed Mentions: 7 Fields: Translation: HumansAnimals
-
Publisher Correction: PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. Nat Commun. 2018 05 25; 9:16217.
Benitez JA, Ma J, D'Antonio M, Boyer A, Camargo MF, Zanca C, Kelly S, Khodadadi-Jamayran A, Jameson NM, Andersen M, Miletic H, Saberi S, Frazer KA, Cavenee WK, Furnari FB. PMID: 29799523.
View in: PubMed Mentions: Fields:
-
MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells. Proc Natl Acad Sci U S A. 2018 05 29; 115(22):5768-5773.
Talukdar S, Pradhan AK, Bhoopathi P, Shen XN, August LA, Windle JJ, Sarkar D, Furnari FB, Cavenee WK, Das SK, Emdad L, Fisher PB. PMID: 29760085.
View in: PubMed Mentions: 16 Fields: Translation: HumansCells
-
Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts. J Vis Exp. 2018 04 26; (134).
Benitez JA, Zanca C, Ma J, Cavenee WK, Furnari FB. PMID: 29757276.
View in: PubMed Mentions: 1 Fields: Translation: HumansAnimalsCells
-
FHL2 interacts with EGFR to promote glioblastoma growth. Oncogene. 2018 03; 37(10):1386-1398.
PMID: 29321665.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
-
Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity. Genes Dev. 2017 06 15; 31(12):1212-1227.
Zanca C, Villa GR, Benitez JA, Thorne AH, Koga T, D'Antonio M, Ikegami S, Ma J, Boyer AD, Banisadr A, Jameson NM, Parisian AD, Eliseeva OV, Barnabe GF, Liu F, Wu S, Yang H, Wykosky J, Frazer KA, Verkhusha VV, Isaguliants MG, Weiss WA, Gahman TC, Shiau AK, Chen CC, Mischel PS, Cavenee WK, Furnari FB. PMID: 28724615.
View in: PubMed Mentions: 13 Fields: Translation: HumansAnimalsCells
-
PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3. Nat Commun. 2017 05 12; 8:15223.
PMID: 28497778.
View in: PubMed Mentions: 25 Fields: Translation: HumansAnimalsCells
-
Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity. Nature. 2017 03 02; 543(7643):122-125.
PMID: 28178237.
View in: PubMed Mentions: 89 Fields: Translation: HumansCells
-
Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin. Proc Natl Acad Sci U S A. 2017 01 10; 114(2):370-375.
PMID: 28011764.
View in: PubMed Mentions: 24 Fields: Translation: HumansAnimalsCells
-
Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme. J Control Release. 2016 12 28; 244(Pt A):14-23.
PMID: 27825958.
View in: PubMed Mentions: 12 Fields: Translation: HumansAnimalsCells
-
An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers. Cancer Cell. 2016 Nov 14; 30(5):683-693.
PMID: 27746144.
View in: PubMed Mentions: 47 Fields: Translation: HumansAnimalsCells
-
The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-). Cancer Res. 2016 05 15; 76(10):2954-63.
PMID: 26980765.
View in: PubMed Mentions: 20 Fields: Translation: HumansAnimalsCells
-
Epidermal growth factor receptor targeting and challenges in glioblastoma. Neuro Oncol. 2016 07; 18(7):914-8.
PMID: 26755074.
View in: PubMed Mentions: 44 Fields: Translation: HumansAnimalsCells
-
EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling. Mol Cell. 2015 Oct 15; 60(2):307-18.
PMID: 26455392.
View in: PubMed Mentions: 57 Fields: Translation: HumansAnimalsCells
-
Orthogonal targeting of EGFRvIII expressing glioblastomas through simultaneous EGFR and PLK1 inhibition. Oncotarget. 2015 May 20; 6(14):11751-67.
PMID: 26059434.
View in: PubMed Mentions: 3 Fields: Translation: HumansAnimalsCells
-
Heterogeneity of epidermal growth factor receptor signalling networks in glioblastoma. Nat Rev Cancer. 2015 May; 15(5):302-10.
PMID: 25855404.
View in: PubMed Mentions: 101 Fields: Translation: HumansCells
-
Cancer-associated protein kinase C mutations reveal kinase's role as tumor suppressor. Cell. 2015 Jan 29; 160(3):489-502.
PMID: 25619690.
View in: PubMed Mentions: 82 Fields: Translation: HumansAnimalsCells
-
A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma. Cancer Res. 2015 Jan 15; 75(2):394-404.
PMID: 25432173.
View in: PubMed Mentions: 19 Fields: Translation: HumansAnimalsCells
-
Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling. Oncogene. 2015 Jul 30; 34(31):4078-88.
PMID: 25347738.
View in: PubMed Mentions: 12 Fields: Translation: HumansAnimalsCells
-
EGFR phosphorylation of DCBLD2 recruits TRAF6 and stimulates AKT-promoted tumorigenesis. J Clin Invest. 2014 Sep; 124(9):3741-56.
PMID: 25061874.
View in: PubMed Mentions: 33 Fields: Translation: HumansCells
-
A unified nomenclature and amino acid numbering for human PTEN. Sci Signal. 2014 Jul 01; 7(332):pe15.
PMID: 24985344.
View in: PubMed Mentions: 22 Fields: Translation: HumansCells
-
Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals. Oncogene. 2015 Mar 05; 34(10):1270-9.
PMID: 24662834.
View in: PubMed Mentions: 7 Fields: Translation: HumansCells
-
Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma. Oncotarget. 2014 Feb 28; 5(4):882-93.
PMID: 24658464.
View in: PubMed Mentions: 47 Fields: Translation: HumansAnimalsCells
-
Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity. Cancer Res. 2014 Mar 01; 74(5):1429-39.
PMID: 24436148.
View in: PubMed Mentions: 31 Fields: Translation: HumansAnimalsCells
-
Targeted therapy resistance mediated by dynamic regulation of extrachromosomal mutant EGFR DNA. Science. 2014 Jan 03; 343(6166):72-6.
PMID: 24310612.
View in: PubMed Mentions: 146 Fields: Translation: HumansAnimalsCells
-
Therapeutic resistance in cancer: microRNA regulation of EGFR signaling networks. Cancer Biol Med. 2013 Dec; 10(4):192-205.
PMID: 24349829.
View in: PubMed Mentions:
-
The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas. Clin Cancer Res. 2013 Oct 15; 19(20):5722-32.
PMID: 24030701.
View in: PubMed Mentions: 16 Fields: Translation: HumansAnimalsCells
-
EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180. Oncogene. 2014 May 08; 33(19):2504-12.
PMID: 23728337.
View in: PubMed Mentions: 34 Fields: Translation: HumansAnimalsCells
-
A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments. Carcinogenesis. 2013 Apr; 34(4):725-38.
PMID: 23455378.
View in: PubMed Mentions: 25 Fields: Translation: Humans
-
PML mediates glioblastoma resistance to mammalian target of rapamycin (mTOR)-targeted therapies. Proc Natl Acad Sci U S A. 2013 Mar 12; 110(11):4339-44.
PMID: 23440206.
-
A kinome-wide RNAi screen in Drosophila Glia reveals that the RIO kinases mediate cell proliferation and survival through TORC2-Akt signaling in glioblastoma. PLoS Genet. 2013; 9(2):e1003253.
PMID: 23459592.
View in: PubMed Mentions: 29 Fields: Translation: HumansAnimalsCells
-
Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. Proc Natl Acad Sci U S A. 2012 Aug 28; 109(35):14164-9.
PMID: 22891331.
View in: PubMed Mentions: 44 Fields: Translation: HumansAnimalsCells
-
Nuclear EGFRvIII-STAT5b complex contributes to glioblastoma cell survival by direct activation of the Bcl-XL promoter. Int J Cancer. 2013 Feb 01; 132(3):509-20.
PMID: 22729867.
View in: PubMed Mentions: 23 Fields: Translation: HumansAnimalsCells
-
Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev. 2012 Apr 15; 26(8):756-84.
PMID: 22508724.
View in: PubMed Mentions: 225 Fields: Translation: HumansCells
-
Targeting EGFR for treatment of glioblastoma: molecular basis to overcome resistance. Curr Cancer Drug Targets. 2012 Mar; 12(3):197-209.
PMID: 22268382.
View in: PubMed Mentions: 68 Fields: Translation: HumansAnimals
-
Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3018-23.
PMID: 22323579.
View in: PubMed Mentions: 28 Fields: Translation: HumansCells
-
Guanylate binding protein 1 is a novel effector of EGFR-driven invasion in glioblastoma. J Exp Med. 2011 Dec 19; 208(13):2657-73.
PMID: 22162832.
View in: PubMed Mentions: 19 Fields: Translation: HumansAnimalsCells
-
EGFRvIII promotes glioma angiogenesis and growth through the NF-κB, interleukin-8 pathway. Oncogene. 2012 Sep 06; 31(36):4054-66.
Bonavia R, Inda MM, Vandenberg S, Cheng SY, Nagane M, Hadwiger P, Tan P, Sah DW, Cavenee WK, Furnari FB. PMID: 22139077.
View in: PubMed Mentions: 76 Fields: Translation: HumansAnimalsCells
-
Activation of Rac1 by Src-dependent phosphorylation of Dock180(Y1811) mediates PDGFRa-stimulated glioma tumorigenesis in mice and humans. J Clin Invest. 2011 Dec; 121(12):4670-84.
PMID: 22080864.
View in: PubMed Mentions: 47 Fields: Translation: HumansAnimalsCells
-
Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):15984-9.
PMID: 21896743.
View in: PubMed Mentions: 33 Fields: Translation: HumansAnimalsCells
-
Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism. J Cell Sci. 2011 Sep 01; 124(Pt 17):2938-50.
PMID: 21878501.
View in: PubMed Mentions: 20 Fields: Translation: HumansCells
-
Report from the fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop. Neuro Oncol. 2011 Jul; 13(7):692-9.
PMID: 21727208.
View in: PubMed Mentions: 4 Fields: Translation: HumansAnimals
-
MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression. Mol Cancer Res. 2011 Aug; 9(8):1100-11.
Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, Zhou X, Tewari M, Furnari FB, Taniguchi T. PMID: 21693595.
View in: PubMed Mentions: 61 Fields: Translation: HumansCells
-
Heterogeneity maintenance in glioblastoma: a social network. Cancer Res. 2011 Jun 15; 71(12):4055-60.
Bonavia R, Inda MM, Cavenee WK, Furnari FB. PMID: 21628493.
View in: PubMed Mentions: 181 Fields: Translation: HumansAnimalsCells
-
Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ?EGFR. J Proteome Res. 2011 Mar 04; 10(3):1343-52.
Chumbalkar V, Latha K, Hwang Y, Maywald R, Hawley L, Sawaya R, Diao L, Baggerly K, Cavenee WK, Furnari FB, Bogler O. PMID: 21214269.
View in: PubMed Mentions: 21 Fields: Translation: HumansAnimalsCells
-
Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations. Chin J Cancer. 2011 Jan; 30(1):5-12.
Wykosky J, Fenton T, Furnari F, Cavenee WK. PMID: 21192840.
View in: PubMed Mentions: 42 Fields: Translation: HumansCells
-
Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma. J Clin Invest. 2011 Jan; 121(1):161-73.
PMID: 21183793.
View in: PubMed Mentions: 43 Fields: Translation: HumansAnimalsCells
-
Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma. Genes Dev. 2010 Aug 15; 24(16):1731-45.
Inda MM, Bonavia R, Mukasa A, Narita Y, Sah DW, Vandenberg S, Brennan C, Johns TG, Bachoo R, Hadwiger P, Tan P, Depinho RA, Cavenee W, Furnari F. PMID: 20713517.
View in: PubMed Mentions: 212 Fields: Translation: HumansAnimalsCells
-
Gene-expression forum: Decoy for microRNAs. Nature. 2010 Jun 24; 465(7301):1016-7.
Rigoutsos I, Furnari F. PMID: 20577197.
View in: PubMed Mentions: 21 Fields: Translation: HumansCells
-
Targeting EGFR induced oxidative stress by PARP1 inhibition in glioblastoma therapy. PLoS One. 2010 May 24; 5(5):e10767.
Nitta M, Kozono D, Kennedy R, Stommel J, Ng K, Zinn PO, Kushwaha D, Kesari S, Inda MM, Wykosky J, Furnari F, Hoadley KA, Chin L, DePinho RA, Cavenee WK, D'Andrea A, Chen CC. PMID: 20532243.
View in: PubMed Mentions: 29 Fields: Translation: HumansCells
-
Escape from targeted inhibition: the dark side of kinase inhibitor therapy. . 2010 May; 9(9):1661-2.
Wykosky J, Mukasa A, Furnari F, Cavenee WK. PMID: 20404502.
View in: PubMed Mentions:
-
Phosphotyrosine signaling analysis of site-specific mutations on EGFRvIII identifies determinants governing glioblastoma cell growth. Mol Biosyst. 2010 Jul; 6(7):1227-37.
Huang PH, Miraldi ER, Xu AM, Kundukulam VA, Del Rosario AM, Flynn RA, Cavenee WK, Furnari FB, White FM. PMID: 20461251.
View in: PubMed Mentions: 23 Fields: Translation: HumansCells
-
Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence. Proc Natl Acad Sci U S A. 2010 Feb 09; 107(6):2616-21.
Mukasa A, Wykosky J, Ligon KL, Chin L, Cavenee WK, Furnari F. PMID: 20133782.
View in: PubMed Mentions: 35 Fields: Translation: HumansAnimalsCells
-
Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients. Cancer Res. 2009 Sep 01; 69(17):6889-98.
Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, Seligson D, Chakravari A, Lee FY, Weinmann R, Cloughesy TF, Nelson SF, Bergers G, Graeber T, Furnari FB, James CD, Cavenee WK, Johns TG, Mischel PS. PMID: 19690143.
View in: PubMed Mentions: 76 Fields: Translation: HumansAnimalsCells
-
EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma. Cancer Res. 2009 May 15; 69(10):4252-9.
Mukherjee B, McEllin B, Camacho CV, Tomimatsu N, Sirasanagandala S, Nannepaga S, Hatanpaa KJ, Mickey B, Madden C, Maher E, Boothman DA, Furnari F, Cavenee WK, Bachoo RM, Burma S. PMID: 19435898.
View in: PubMed Mentions: 97 Fields: Translation: HumansAnimalsCells
-
A drosophila model for EGFR-Ras and PI3K-dependent human glioma. PLoS Genet. 2009 Feb; 5(2):e1000374.
Read RD, Cavenee WK, Furnari FB, Thomas JB. PMID: 19214224.
View in: PubMed Mentions: 71 Fields: Translation: HumansAnimalsCells
-
Feedback circuit among INK4 tumor suppressors constrains human glioblastoma development. Cancer Cell. 2008 Apr; 13(4):355-64.
Wiedemeyer R, Brennan C, Heffernan TP, Xiao Y, Mahoney J, Protopopov A, Zheng H, Bignell G, Furnari F, Cavenee WK, Hahn WC, Ichimura K, Collins VP, Chu GC, Stratton MR, Ligon KL, Futreal PA, Chin L. PMID: 18394558.
View in: PubMed Mentions: 64 Fields: Translation: HumansAnimalsCells
-
Malignant astrocytic glioma: genetics, biology, and paths to treatment. Genes Dev. 2007 Nov 01; 21(21):2683-710.
Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. PMID: 17974913.
View in: PubMed Mentions: 863 Fields: Translation: HumansAnimals
-
Uncovering therapeutic targets for glioblastoma: a systems biology approach. . 2007 Nov 15; 6(22):2750-4.
Huang PH, Cavenee WK, Furnari FB, White FM. PMID: 17986864.
View in: PubMed Mentions:
-
Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma. Proc Natl Acad Sci U S A. 2007 Jul 31; 104(31):12867-72.
Huang PH, Mukasa A, Bonavia R, Flynn RA, Brewer ZE, Cavenee WK, Furnari FB, White FM. PMID: 17646646.
View in: PubMed Mentions: 172 Fields: Translation: HumansAnimalsCells
-
The efficacy of epidermal growth factor receptor-specific antibodies against glioma xenografts is influenced by receptor levels, activation status, and heterodimerization. Clin Cancer Res. 2007 Mar 15; 13(6):1911-25.
Johns TG, Perera RM, Vernes SC, Vitali AA, Cao DX, Cavenee WK, Scott AM, Furnari FB. PMID: 17363548.
View in: PubMed Mentions: 36 Fields: Translation: HumansAnimalsCells
-
Mutant epidermal growth factor receptor (EGFRvIII) contributes to head and neck cancer growth and resistance to EGFR targeting. Clin Cancer Res. 2006 Sep 01; 12(17):5064-73.
Sok JC, Coppelli FM, Thomas SM, Lango MN, Xi S, Hunt JL, Freilino ML, Graner MW, Wikstrand CJ, Bigner DD, Gooding WE, Furnari FB, Grandis JR. PMID: 16951222.
View in: PubMed Mentions: 165 Fields: Translation: HumansAnimalsCells
-
PCAF modulates PTEN activity. J Biol Chem. 2006 Sep 08; 281(36):26562-8.
Okumura K, Mendoza M, Bachoo RM, DePinho RA, Cavenee WK, Furnari FB. PMID: 16829519.
View in: PubMed Mentions: 71 Fields: Translation: HumansAnimalsCells
-
The PTEN and INK4A/ARF tumor suppressors maintain myelolymphoid homeostasis and cooperate to constrain histiocytic sarcoma development in humans. Cancer Cell. 2006 May; 9(5):379-90.
Carrasco DR, Fenton T, Sukhdeo K, Protopopova M, Enos M, You MJ, Di Vizio D, Divicio D, Nogueira C, Stommel J, Pinkus GS, Fletcher C, Hornick JL, Cavenee WK, Furnari FB, Depinho RA. PMID: 16697958.
View in: PubMed Mentions: 29 Fields: Translation: HumansAnimalsCells
-
Treatment of human tumor xenografts with monoclonal antibody 806 in combination with a prototypical epidermal growth factor receptor-specific antibody generates enhanced antitumor activity. Clin Cancer Res. 2005 Sep 01; 11(17):6390-9.
Perera RM, Narita Y, Furnari FB, Gan HK, Murone C, Ahlkvist M, Luwor RB, Burgess AW, Stockert E, Jungbluth AA, Old LJ, Cavenee WK, Scott AM, Johns TG. PMID: 16144944.
View in: PubMed Mentions: 27 Fields: Translation: HumansAnimalsCells
-
PTEN: a novel anti-oncogenic function independent of phosphatase activity. . 2005 Apr; 4(4):540-2.
Okumura K, Zhao M, DePinho RA, Furnari FB, Cavenee WK. PMID: 15753657.
View in: PubMed Mentions:
-
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth. Mol Cell. 2005 Apr 01; 18(1):13-24.
Gao T, Furnari F, Newton AC. PMID: 15808505.
View in: PubMed Mentions: 347 Fields: Translation: HumansCells
-
Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2703-6.
Okumura K, Zhao M, Depinho RA, Furnari FB, Cavenee WK. PMID: 15659546.
View in: PubMed Mentions: 44 Fields: Translation: HumansAnimals
-
Alix/AIP1 antagonizes epidermal growth factor receptor downregulation by the Cbl-SETA/CIN85 complex. Mol Cell Biol. 2004 10; 24(20):8981-93.
Schmidt MHH, Hoeller D, Yu J, Furnari FB, Cavenee WK, Dikic I, Bögler O. PMID: 15456872.
View in: PubMed Mentions: 54 Fields: Translation: HumansAnimalsCells
-
Dynamics of centromere and kinetochore proteins; implications for checkpoint signaling and silencing. Curr Biol. 2004 Jun 08; 14(11):942-52.
Shah JV, Botvinick E, Bonday Z, Furnari F, Berns M, Cleveland DW. PMID: 15182667.
View in: PubMed Mentions: 137 Fields: Translation: HumansAnimalsCells
-
Immunohistochemical analysis of the mutant epidermal growth factor, deltaEGFR, in glioblastoma. Brain Tumor Pathol. 2004; 21(2):53-6.
Nishikawa R, Sugiyama T, Narita Y, Furnari F, Cavenee WK, Matsutani M. PMID: 15700833.
View in: PubMed Mentions: 49 Fields: Translation: Humans
-
The generation and utilization of a cancer-oriented representation of the human transcriptome by using expressed sequence tags. Proc Natl Acad Sci U S A. 2003 Nov 11; 100(23):13418-23.
Brentani H, Caballero OL, Camargo AA, da Silva AM, da Silva WA, Dias Neto E, Grivet M, Gruber A, Guimaraes PE, Hide W, Iseli C, Jongeneel CV, Kelso J, Nagai MA, Ojopi EP, Osorio EC, Reis EM, Riggins GJ, Simpson AJ, de Souza S, Stevenson BJ, Strausberg RL, Tajara EH, Verjovski-Almeida S, Acencio ML, Bengtson MH, Bettoni F, Bodmer WF, Briones MR, Camargo LP, Cavenee W, Cerutti JM, Coelho Andrade LE, Costa dos Santos PC, Ramos Costa MC, da Silva IT, Estécio MR, Sa Ferreira K, Furnari FB, Faria M, Galante PA, Guimaraes GS, Holanda AJ, Kimura ET, Leerkes MR, Lu X, Maciel RM, Martins EA, Massirer KB, Melo AS, Mestriner CA, Miracca EC, Miranda LL, Nobrega FG, Oliveira PS, Paquola AC, Pandolfi JR, Campos Pardini MI, Passetti F, Quackenbush J, Schnabel B, Sogayar MC, Souza JE, Valentini SR, Zaiats AC, Amaral EJ, Arnaldi LA, de Araújo AG, de Bessa SA, Bicknell DC, Ribeiro de Camaro ME, Carraro DM, Carrer H, Carvalho AF, Colin C, Costa F, Curcio C, Guerreiro da Silva ID, Pereira da Silva N, Dellamano M, El-Dorry H, Espreafico EM, Scattone Ferreira AJ, Ayres Ferreira C, Fortes MA, Gama AH, Giannella-Neto D, Giannella ML, Giorgi RR, Goldman GH, Goldman MH, Hackel C, Ho PL, Kimura EM, Kowalski LP, Krieger JE, Leite LC, Lopes A, Luna AM, Mackay A, Mari SK, Marques AA, Martins WK, Montagnini A, Mourão Neto M, Nascimento AL, Neville AM, Nobrega MP, O'Hare MJ, Otsuka AY, Ruas de Melo AI, Paco-Larson ML, Guimarães Pereira G, Pereira da Silva N, Pesquero JB, Pessoa JG, Rahal P, Rainho CA, Rodrigues V, Rogatto SR, Romano CM, Romeiro JG, Rossi BM, Rusticci M, Guerra de Sá R, Sant' Anna SC, Sarmazo ML, Silva TC, Soares FA, Sonati Mde F, de Freitas Sousa J, Queiroz D, Valente V, Vettore AL, Villanova FE, Zago MA, Zalcberg H. PMID: 14593198.
View in: PubMed Mentions: 41 Fields: Translation: Humans
-
Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization. Proc Natl Acad Sci U S A. 2003 05 27; 100(11):6505-10.
Schmidt MHH, Furnari FB, Cavenee WK, Bögler O. PMID: 12734385.
View in: PubMed Mentions: 55 Fields: Translation: HumansAnimalsCells
-
Mutant epidermal growth factor receptor signaling down-regulates p27 through activation of the phosphatidylinositol 3-kinase/Akt pathway in glioblastomas. Cancer Res. 2002 Nov 15; 62(22):6764-9.
Narita Y, Nagane M, Mishima K, Huang HJ, Furnari FB, Cavenee WK. PMID: 12438278.
View in: PubMed Mentions: 61 Fields: Translation: HumansAnimalsCells
-
A novel seven transmembrane receptor induced during the early steps of astrocyte differentiation identified by differential expression. J Neurochem. 2002 May; 81(3):575-88.
De Smet C, Nishimori H, Furnari FB, Bögler O, Huang HJ, Cavenee WK. PMID: 12065666.
View in: PubMed Mentions: 2 Fields: Translation: AnimalsCells
-
The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor. J Biol Chem. 2001 Dec 07; 276(49):46313-8.
Klingler-Hoffmann M, Fodero-Tavoletti MT, Mishima K, Narita Y, Cavenee WK, Furnari FB, Huang HJ, Tiganis T. PMID: 11514572.
View in: PubMed Mentions: 17 Fields: Translation: HumansAnimalsCells
-
Trypanosoma cruzi trans-sialidase: a potent and specific survival factor for human Schwann cells by means of phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A. 2001 Aug 14; 98(17):9936-41.
Chuenkova MV, Furnari FB, Cavenee WK, Pereira MA. PMID: 11481434.
View in: PubMed Mentions: 28 Fields: Translation: HumansAnimalsCells
-
Malignant glioma: genetics and biology of a grave matter. Genes Dev. 2001 Jun 01; 15(11):1311-33.
Maher EA, Furnari FB, Bachoo RM, Rowitch DH, Louis DN, Cavenee WK, DePinho RA. PMID: 11390353.
View in: PubMed Mentions: 397 Fields: Translation: HumansAnimals
-
Non-isotopic silver-stained SSCP is more sensitive than automated direct sequencing for the detection of PTEN mutations in a mixture of DNA extracted from normal and tumor cells. Int J Oncol. 2001 May; 18(5):1023-6.
Fan X, Furnari FB, Cavenee WK, Castresana JS. PMID: 11295051.
View in: PubMed Mentions: 16 Fields: Translation: Humans
-
IGF-I receptor signaling in a prostatic cancer cell line with a PTEN mutation. Oncogene. 2000 May 18; 19(22):2687-94.
Reiss K, Wang JY, Romano G, Furnari FB, Cavenee WK, Morrione A, Tu X, Baserga R. PMID: 10851068.
View in: PubMed Mentions: 18 Fields: Translation: HumansAnimalsCells
-
SETA: a novel SH3 domain-containing adapter molecule associated with malignancy in astrocytes. Neuro Oncol. 2000 01; 2(1):6-15.
Bögler O, Furnari FB, Kindler-Roehrborn A, Sykes VW, Yung R, Huang HJ, Cavenee WK. PMID: 11302255.
View in: PubMed Mentions: 15 Fields: Translation: HumansAnimalsCells
-
PTEN gene transfer in human malignant glioma: sensitization to irradiation and CD95L-induced apoptosis. Oncogene. 1999 Jul 08; 18(27):3936-43.
Wick W, Furnari FB, Naumann U, Cavenee WK, Weller M. PMID: 10435616.
View in: PubMed Mentions: 25 Fields: Translation: HumansCells
-
The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells. Cancer Res. 1998 Nov 15; 58(22):5002-8.
Furnari FB, Huang HJ, Cavenee WK. PMID: 9823298.
View in: PubMed Mentions: 110 Fields: Translation: HumansCells
-
In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9418-23.
Robertson GP, Furnari FB, Miele ME, Glendening MJ, Welch DR, Fountain JW, Lugo TG, Huang HJ, Cavenee WK. PMID: 9689095.
View in: PubMed Mentions: 27 Fields: Translation: HumansCells
-
Absence of PTEN/MMAC1 germ-line mutations in sporadic Bannayan-Riley-Ruvalcaba syndrome. Cancer Res. 1998 Jul 01; 58(13):2724-6.
Carethers JM, Furnari FB, Zigman AF, Lavine JE, Jones MC, Graham GE, Teebi AS, Huang HJ, Ha HT, Chauhan DP, Chang CL, Cavenee WK, Boland CR. PMID: 9661881.
View in: PubMed Mentions: 5 Fields: Translation: Humans
-
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain. Proc Natl Acad Sci U S A. 1997 Nov 11; 94(23):12479-84.
Furnari FB, Lin H, Huang HS, Cavenee WK. PMID: 9356475.
View in: PubMed Mentions: 117 Fields: Translation: HumansCells
-
Molecular biology of malignant degeneration of astrocytoma. Pediatr Neurosurg. 1996; 24(1):41-9.
Furnari FB, Huang HJ, Cavenee WK. PMID: 8817614.
View in: PubMed Mentions: 5 Fields: Translation: Humans
-
Loss of P16INK4 expression is frequent in high grade gliomas. Cancer Res. 1995 May 01; 55(9):1941-5.
Nishikawa R, Furnari FB, Lin H, Arap W, Berger MS, Cavenee WK, Su Huang HJ. PMID: 7728764.
View in: PubMed Mentions: 28 Fields: Translation: HumansCells
-
Replacement of the p16/CDKN2 gene suppresses human glioma cell growth. Cancer Res. 1995 Mar 15; 55(6):1351-4.
Arap W, Nishikawa R, Furnari FB, Cavenee WK, Huang HJ. PMID: 7882335.
View in: PubMed Mentions: 20 Fields: Translation: HumansCells
-
Genetics and malignant progression of human brain tumours. Cancer Surv. 1995; 25:233-75.
Furnari FB, Huang HJ, Cavenee WK. PMID: 8718522.
View in: PubMed Mentions: 13 Fields: Translation: HumansAnimalsCells
-
RAZ, an Epstein-Barr virus transdominant repressor that modulates the viral reactivation mechanism. J Virol. 1994 Mar; 68(3):1827-36.
Furnari FB, Zacny V, Quinlivan EB, Kenney S, Pagano JS. PMID: 8107245.
View in: PubMed Mentions: 24 Fields: Translation: HumansCells
-
Unconventional processing of the 3' termini of the Epstein-Barr virus DNA polymerase mRNA. Proc Natl Acad Sci U S A. 1993 Jan 15; 90(2):378-82.
Furnari FB, Adams MD, Pagano JS. PMID: 8093641.
View in: PubMed Mentions: 18 Fields: Translation: AnimalsCells
-
Regulation of the Epstein-Barr virus DNA polymerase gene. J Virol. 1992 May; 66(5):2837-45.
Furnari FB, Adams MD, Pagano JS. PMID: 1313904.
View in: PubMed Mentions: 24 Fields: Translation: AnimalsCells
This graph shows the total number of publications by year. To see the data as text, click here.
This graph shows the total number of publications by year. To return to the graph, click here.
Year | Publications |
---|
1992 | 1 | 1993 | 1 | 1994 | 1 | 1995 | 3 | 1996 | 1 | 1997 | 1 | 1998 | 3 | 1999 | 1 | 2000 | 2 | 2001 | 4 | 2002 | 2 | 2003 | 2 | 2004 | 3 | 2005 | 4 | 2006 | 3 | 2007 | 4 | 2008 | 1 | 2009 | 3 | 2010 | 7 | 2011 | 10 | 2012 | 5 | 2013 | 7 | 2014 | 7 | 2015 | 4 | 2016 | 5 | 2017 | 3 | 2018 | 8 | 2019 | 10 | 2020 | 8 | 2021 | 2 |
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
This graph shows the number and percent of publications by field.
Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications.
Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written.
To see the data as text, click here.
newest
oldest
line numbers
double spacing
all authors
publication IDs
|
Derived automatically from this person's publications.
_
People in Profiles who have published with this person.
_
People who share similar concepts with this person.
_
Search Department
_
|