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Karen Oegema

Title(s)Professor, Cellular and Molecular Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0660
La Jolla CA 92093
Phone8/5-34--9714
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    The Oegema lab takes parallel approaches in mammalian cells and using the C. elegans embryo as a metazoan model system to study cell division and embryonic development.

    Research Focus Area:

  • Cell Division and Cell Cycle Control

  • Genetics and Genomics

  • Signal Transduction

  • Stem Cell Biology

  • Systems Biology


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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. Nature. 2020 Sep; 585(7825):440-446. Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K. PMID: 32908304.
      View in: PubMed   Mentions:
    2. A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis. Curr Biol. 2020 Aug 17; 30(16):3101-3115.e11. Gómez-Cavazos JS, Lee KY, Lara-González P, Li Y, Desai A, Shiau AK, Oegema K. PMID: 32619481.
      View in: PubMed   Mentions:    Fields:    
    3. A Semi-high-throughput Imaging Method and Data Visualization Toolkit to Analyze C. elegans Embryonic Development. J Vis Exp. 2019 10 29; (152). Khaliullin RN, Hendel JM, Gerson-Gurwitz A, Wang S, Ochoa SD, Zhao Z, Desai A, Oegema K, Green RA. PMID: 31736498.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    4. The G2-to-M Transition Is Ensured by a Dual Mechanism that Protects Cyclin B from Degradation by Cdc20-Activated APC/C. Dev Cell. 2019 11 04; 51(3):313-325.e10. Lara-Gonzalez P, Moyle MW, Budrewicz J, Mendoza-Lopez J, Oegema K, Desai A. PMID: 31588029.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    5. Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. J Cell Biol. 2019 11 04; 218(11):3795-3811. Gerson-Gurwitz A, Worby CA, Lee KY, Khaliullin R, Bouffard J, Cheerambathur D, Oegema K, Cram EJ, Dixon JE, Desai A. PMID: 31541016.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    6. Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity. Curr Biol. 2019 09 23; 29(18):3072-3080.e5. Gemble S, Simon A, Pennetier C, Dumont M, Hervé S, Meitinger F, Oegema K, Rodriguez R, Almouzni G, Fachinetti D, Basto R. PMID: 31495582.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. A high-content imaging approach to profile C. elegans embryonic development. Development. 2019 04 11; 146(7). Wang S, Ochoa SD, Khaliullin RN, Gerson-Gurwitz A, Hendel JM, Zhao Z, Biggs R, Chisholm AD, Desai A, Oegema K, Green RA. PMID: 30890570.
      View in: PubMed   Mentions:    Fields:    Translation:Animals
    8. The Kinetochore-Microtubule Coupling Machinery Is Repurposed in Sensory Nervous System Morphogenesis. Dev Cell. 2019 03 25; 48(6):864-872.e7. Cheerambathur DK, Prevo B, Chow TL, Hattersley N, Wang S, Zhao Z, Kim T, Gerson-Gurwitz A, Oegema K, Green R, Desai A. PMID: 30827898.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    9. The ARP2/3 complex prevents excessive formin activity during cytokinesis. Mol Biol Cell. 2019 01 01; 30(1):96-107. Chan FY, Silva AM, Saramago J, Pereira-Sousa J, Brighton HE, Pereira M, Oegema K, Gassmann R, Carvalho AX. PMID: 30403552.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    10. CFI-400945 is not a selective cellular PLK4 inhibitor. Proc Natl Acad Sci U S A. 2018 11 13; 115(46):E10808-E10809. Oegema K, Davis RL, Lara-Gonzalez P, Desai A, Shiau AK. PMID: 30377272.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    11. CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia. Elife. 2018 07 10; 7. Lee KY, Green RA, Gutierrez E, Gomez-Cavazos JS, Kolotuev I, Wang S, Desai A, Groisman A, Oegema K. PMID: 29989548.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    12. A positive-feedback-based mechanism for constriction rate acceleration during cytokinesis in Caenorhabditis elegans. Elife. 2018 07 02; 7. Khaliullin RN, Green RA, Shi LZ, Gomez-Cavazos JS, Berns MW, Desai A, Oegema K. PMID: 29963981.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    13. Correction: Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation (doi:10.1242/dev.126615). Development. 2018 05 14; 145(10). Quintin S, Wang S, Pontabry J, Bender A, Robin F, Hyenne V, Landmann F, Gally C, Oegema K, Labouesse M. PMID: 29759977.
      View in: PubMed   Mentions:    Fields:    
    14. Employing the one-cell C. elegans embryo to study cell division processes. Methods Cell Biol. 2018; 144:185-231. Hattersley N, Lara-Gonzalez P, Cheerambathur D, Gomez-Cavazos JS, Kim T, Prevo B, Khaliullin R, Lee KY, Ohta M, Green R, Oegema K, Desai A. PMID: 29804670.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    15. TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis. J Cell Biol. 2018 03 05; 217(3):837-848. Mangal S, Sacher J, Kim T, Osório DS, Motegi F, Carvalho AX, Oegema K, Zanin E. PMID: 29311228.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    16. A toolkit for GFP-mediated tissue-specific protein degradation in C. elegans. Development. 2017 07 15; 144(14):2694-2701. Wang S, Tang NH, Lara-Gonzalez P, Zhao Z, Cheerambathur DK, Prevo B, Chisholm AD, Desai A, Oegema K. PMID: 28619826.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    17. Kinetochores accelerate or delay APC/C activation by directing Cdc20 to opposing fates. Genes Dev. 2017 06 01; 31(11):1089-1094. Kim T, Lara-Gonzalez P, Prevo B, Meitinger F, Cheerambathur DK, Oegema K, Desai A. PMID: 28698300.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    18. Dephosphorylation of the Ndc80 Tail Stabilizes Kinetochore-Microtubule Attachments via the Ska Complex. Dev Cell. 2017 05 22; 41(4):424-437.e4. Cheerambathur DK, Prevo B, Hattersley N, Lewellyn L, Corbett KD, Oegema K, Desai A. PMID: 28535376.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    19. How centrioles acquire the ability to reproduce. Elife. 2017 03 08; 6. Ohta M, Desai A, Oegema K. PMID: 28271993.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    20. Polo-like kinase phosphorylation determines Caenorhabditis elegans centrosome size and density by biasing SPD-5 toward an assembly-competent conformation. Biol Open. 2016 Oct 15; 5(10):1431-1440. Wueseke O, Zwicker D, Schwager A, Wong YL, Oegema K, Jülicher F, Hyman AA, Woodruff JB. PMID: 27591191.
      View in: PubMed   Mentions:
    21. GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. Mol Biol Cell. 2016 12 01; 27(24):3828-3840. Xing M, Peterman MC, Davis RL, Oegema K, Shiau AK, Field SJ. PMID: 27708138.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    22. A Nucleoporin Docks Protein Phosphatase 1 to Direct Meiotic Chromosome Segregation and Nuclear Assembly. Dev Cell. 2016 09 12; 38(5):463-77. Hattersley N, Cheerambathur D, Moyle M, Stefanutti M, Richardson A, Lee KY, Dumont J, Oegema K, Desai A. PMID: 27623381.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimalsCells
    23. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016 07 18; 214(2):155-66. Meitinger F, Anzola JV, Kaulich M, Richardson A, Stender JD, Benner C, Glass CK, Dowdy SF, Desai A, Shiau AK, Oegema K. PMID: 27432897.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansCells
    24. A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions. Cell. 2016 Apr 07; 165(2):396-409. Gerson-Gurwitz A, Wang S, Sathe S, Green R, Yeo GW, Oegema K, Desai A. PMID: 27020753.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    25. Correction: Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. J Cell Biol. 2016 Mar 14; 212(6):737. Kim T, Moyle MW, Lara-Gonzalez P, De Groot C, Oegema K, Desai A. PMID: 26953348.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    26. Non-centrosomal epidermal microtubules act in parallel to LET-502/ROCK to promote C. elegans elongation. Development. 2016 Jan 01; 143(1):160-73. Quintin S, Wang S, Pontabry J, Bender A, Robin F, Hyenne V, Landmann F, Gally C, Oegema K, Labouesse M. PMID: 26586219.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    27. NOCA-1 functions with ?-tubulin and in parallel to Patronin to assemble non-centrosomal microtubule arrays in C. elegans. Elife. 2015 Sep 15; 4:e08649. Wang S, Wu D, Quintin S, Green RA, Cheerambathur DK, Ochoa SD, Desai A, Oegema K. PMID: 26371552.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    28. Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans. J Cell Biol. 2015 May 25; 209(4):507-17. Kim T, Moyle MW, Lara-Gonzalez P, De Groot C, Oegema K, Desai A. PMID: 25987605.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    29. Centrosomes. Regulated assembly of a supramolecular centrosome scaffold in vitro. Science. 2015 May 15; 348(6236):808-12. Woodruff JB, Wueseke O, Viscardi V, Mahamid J, Ochoa SD, Bunkenborg J, Widlund PO, Pozniakovsky A, Zanin E, Bahmanyar S, Zinke A, Hong SH, Decker M, Baumeister W, Andersen JS, Oegema K, Hyman AA. PMID: 25977552.
      View in: PubMed   Mentions: 39     Fields:    Translation:AnimalsCells
    30. Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science. 2015 Jun 05; 348(6239):1155-60. Wong YL, Anzola JV, Davis RL, Yoon M, Motamedi A, Kroll A, Seo CP, Hsia JE, Kim SK, Mitchell JW, Mitchell BJ, Desai A, Gahman TC, Shiau AK, Oegema K. PMID: 25931445.
      View in: PubMed   Mentions: 96     Fields:    Translation:HumansAnimalsCells
    31. Separase Cleaves the N-Tail of the CENP-A Related Protein CPAR-1 at the Meiosis I Metaphase-Anaphase Transition in C. elegans. PLoS One. 2015; 10(4):e0125382. Monen J, Hattersley N, Muroyama A, Stevens D, Oegema K, Desai A. PMID: 25919583.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    32. The CENP-A N-tail confers epigenetic stability to centromeres via the CENP-T branch of the CCAN in fission yeast. Curr Biol. 2015 Feb 02; 25(3):348-356. Folco HD, Campbell CS, May KM, Espinoza CA, Oegema K, Hardwick KG, Grewal SIS, Desai A. PMID: 25619765.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    33. Methods in Cell Biology. Centrosome & Centriole. Preface. Methods Cell Biol. 2015; 129:xvii-xix. Basto R, Oegema K. PMID: 26376502.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    34. The microtubule minus-end-binding protein patronin/PTRN-1 is required for axon regeneration in C. elegans. Cell Rep. 2014 Nov 06; 9(3):874-83. Chuang M, Goncharov A, Wang S, Oegema K, Jin Y, Chisholm AD. PMID: 25437544.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    35. The Caenorhabditis elegans pericentriolar material components SPD-2 and SPD-5 are monomeric in the cytoplasm before incorporation into the PCM matrix. Mol Biol Cell. 2014 Oct 01; 25(19):2984-92. Wueseke O, Bunkenborg J, Hein MY, Zinke A, Viscardi V, Woodruff JB, Oegema K, Mann M, Andersen JS, Hyman AA. PMID: 25103243.
      View in: PubMed   Mentions: 12     Fields:    Translation:AnimalsCells
    36. Structure of the C. elegans ZYG-1 cryptic polo box suggests a conserved mechanism for centriolar docking of Plk4 kinases. Structure. 2014 Aug 05; 22(8):1090-1104. Shimanovskaya E, Viscardi V, Lesigang J, Lettman MM, Qiao R, Svergun DI, Round A, Oegema K, Dong G. PMID: 24980795.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    37. A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint. J Cell Biol. 2014 Mar 03; 204(5):647-57. Moyle MW, Kim T, Hattersley N, Espeut J, Cheerambathur DK, Oegema K, Desai A. PMID: 24567362.
      View in: PubMed   Mentions: 49     Fields:    Translation:AnimalsCells
    38. Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev. 2014 Jan 15; 28(2):121-6. Bahmanyar S, Biggs R, Schuh AL, Desai A, Müller-Reichert T, Audhya A, Dixon JE, Oegema K. PMID: 24449268.
      View in: PubMed   Mentions: 20     Fields:    Translation:AnimalsCells
    39. Meiotic double-strand breaks uncover and protect against mitotic errors in the C. elegans germline. Curr Biol. 2013 Dec 02; 23(23):2400-6. Stevens D, Oegema K, Desai A. PMID: 24239117.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCells
    40. Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Science. 2013 Dec 06; 342(6163):1239-42. Cheerambathur DK, Gassmann R, Cook B, Oegema K, Desai A. PMID: 24231804.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    41. The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules. J Cell Biol. 2013 Nov 11; 203(3):505-20. Green RA, Mayers JR, Wang S, Lewellyn L, Desai A, Audhya A, Oegema K. PMID: 24217623.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    42. Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly. Elife. 2013 Sep 17; 2:e01071. Cottee MA, Muschalik N, Wong YL, Johnson CM, Johnson S, Andreeva A, Oegema K, Lea SM, Raff JW, van Breugel M. PMID: 24052813.
      View in: PubMed   Mentions: 45     Fields:    Translation:HumansCells
    43. A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesis. Dev Cell. 2013 Sep 16; 26(5):496-510. Zanin E, Desai A, Poser I, Toyoda Y, Andree C, Moebius C, Bickle M, Conradt B, Piekny A, Oegema K. PMID: 24012485.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    44. Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Dev Cell. 2013 May 13; 25(3):284-98. Lettman MM, Wong YL, Viscardi V, Niessen S, Chen SH, Shiau AK, Zhou H, Desai A, Oegema K. PMID: 23673331.
      View in: PubMed   Mentions: 30     Fields:    Translation:AnimalsCells
    45. Hierarchical assembly of the eggshell and permeability barrier in C. elegans. J Cell Biol. 2012 Aug 20; 198(4):731-48. Olson SK, Greenan G, Desai A, Müller-Reichert T, Oegema K. PMID: 22908315.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    46. Cytokinesis in animal cells. Annu Rev Cell Dev Biol. 2012; 28:29-58. Green RA, Paluch E, Oegema K. PMID: 22804577.
      View in: PubMed   Mentions: 176     Fields:    Translation:HumansAnimalsCells
    47. An inverse relationship to germline transcription defines centromeric chromatin in C. elegans. Nature. 2012 Apr 08; 484(7395):534-7. Gassmann R, Rechtsteiner A, Yuen KW, Muroyama A, Egelhofer T, Gaydos L, Barron F, Maddox P, Essex A, Monen J, Ercan S, Lieb JD, Oegema K, Strome S, Desai A. PMID: 22495302.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    48. Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore. J Cell Biol. 2012 Feb 20; 196(4):469-82. Espeut J, Cheerambathur DK, Krenning L, Oegema K, Desai A. PMID: 22331849.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    49. Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem. 2012 Jan 27; 287(5):3123-37. Han S, Bahmanyar S, Zhang P, Grishin N, Oegema K, Crooke R, Graham M, Reue K, Dixon JE, Goodman JM. PMID: 22134922.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    50. Rapid de novo centromere formation occurs independently of heterochromatin protein 1 in C. elegans embryos. Curr Biol. 2011 Nov 08; 21(21):1800-7. Yuen KW, Nabeshima K, Oegema K, Desai A. PMID: 22018540.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    51. Acute drug treatment in the early C. elegans embryo. PLoS One. 2011; 6(9):e24656. Carvalho A, Olson SK, Gutierrez E, Zhang K, Noble LB, Zanin E, Desai A, Groisman A, Oegema K. PMID: 21935434.
      View in: PubMed   Mentions: 45     Fields:    Translation:Animals
    52. Uncoordinated loss of chromatid cohesion is a common outcome of extended metaphase arrest. PLoS One. 2011; 6(8):e22969. Stevens D, Gassmann R, Oegema K, Desai A. PMID: 21829677.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansCells
    53. A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell. 2011 Apr 29; 145(3):470-82. Green RA, Kao HL, Audhya A, Arur S, Mayers JR, Fridolfsson HN, Schulman M, Schloissnig S, Niessen S, Laband K, Wang S, Starr DA, Hyman AA, Schedl T, Desai A, Piano F, Gunsalus KC, Oegema K. PMID: 21529718.
      View in: PubMed   Mentions: 93     Fields:    Translation:Animals
    54. The chromosomal passenger complex and centralspindlin independently contribute to contractile ring assembly. J Cell Biol. 2011 Apr 04; 193(1):155-69. Lewellyn L, Carvalho A, Desai A, Maddox AS, Oegema K. PMID: 21464231.
      View in: PubMed   Mentions: 34     Fields:    Translation:AnimalsCells
    55. Affinity purification of protein complexes in C. elegans. Methods Cell Biol. 2011; 106:289-322. Zanin E, Dumont J, Gassmann R, Cheeseman I, Maddox P, Bahmanyar S, Carvalho A, Niessen S, Yates JR, Oegema K, Desai A. PMID: 22118282.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    56. A kinetochore-independent mechanism drives anaphase chromosome separation during acentrosomal meiosis. Nat Cell Biol. 2010 Sep; 12(9):894-901. Dumont J, Oegema K, Desai A. PMID: 20729837.
      View in: PubMed   Mentions: 70     Fields:    Translation:AnimalsCells
    57. Removal of Spindly from microtubule-attached kinetochores controls spindle checkpoint silencing in human cells. Genes Dev. 2010 May; 24(9):957-71. Gassmann R, Holland AJ, Varma D, Wan X, Civril F, Cleveland DW, Oegema K, Salmon ED, Desai A. PMID: 20439434.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    58. Analyzing the effects of delaying aster separation on furrow formation during cytokinesis in the Caenorhabditis elegans embryo. Mol Biol Cell. 2010 Jan 01; 21(1):50-62. Lewellyn L, Dumont J, Desai A, Oegema K. PMID: 19889842.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    59. The hydrolethalus syndrome protein HYLS-1 links core centriole structure to cilia formation. Genes Dev. 2009 Sep 01; 23(17):2046-59. Dammermann A, Pemble H, Mitchell BJ, McLeod I, Yates JR, Kintner C, Desai AB, Oegema K. PMID: 19656802.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansAnimalsCells
    60. Structural memory in the contractile ring makes the duration of cytokinesis independent of cell size. Cell. 2009 May 29; 137(5):926-37. Carvalho A, Desai A, Oegema K. PMID: 19490897.
      View in: PubMed   Mentions: 80     Fields:    Translation:Animals
    61. Systematic analysis in Caenorhabditis elegans reveals that the spindle checkpoint is composed of two largely independent branches. Mol Biol Cell. 2009 Feb; 20(4):1252-67. Essex A, Dammermann A, Lewellyn L, Oegema K, Desai A. PMID: 19109417.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    62. Inhibition of Rac by the GAP activity of centralspindlin is essential for cytokinesis. Science. 2008 Dec 05; 322(5907):1543-6. Canman JC, Lewellyn L, Laband K, Smerdon SJ, Desai A, Bowerman B, Oegema K. PMID: 19056985.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    63. A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Genes Dev. 2008 Sep 01; 22(17):2385-99. Gassmann R, Essex A, Hu JS, Maddox PS, Motegi F, Sugimoto A, O'Rourke SM, Bowerman B, McLeod I, Yates JR, Oegema K, Cheeseman IM, Desai A. PMID: 18765790.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    64. SAS-4 is recruited to a dynamic structure in newly forming centrioles that is stabilized by the gamma-tubulin-mediated addition of centriolar microtubules. J Cell Biol. 2008 Feb 25; 180(4):771-85. Dammermann A, Maddox PS, Desai A, Oegema K. PMID: 18299348.
      View in: PubMed   Mentions: 59     Fields:    Translation:AnimalsCells
    65. Expression and imaging of fluorescent proteins in the C. elegans gonad and early embryo. Methods Cell Biol. 2008; 85:179-218. Green RA, Audhya A, Pozniakovsky A, Dammermann A, Pemble H, Monen J, Portier N, Hyman A, Desai A, Oegema K. PMID: 18155464.
      View in: PubMed   Mentions: 33     Fields:    Translation:Animals
    66. MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation. PLoS One. 2007 Sep 26; 2(9):e956. Audhya A, McLeod IX, Yates JR, Oegema K. PMID: 17895996.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansAnimalsCells
    67. A role for Rab5 in structuring the endoplasmic reticulum. J Cell Biol. 2007 Jul 02; 178(1):43-56. Audhya A, Desai A, Oegema K. PMID: 17591921.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    68. Anillin and the septins promote asymmetric ingression of the cytokinetic furrow. Dev Cell. 2007 May; 12(5):827-35. Maddox AS, Lewellyn L, Desai A, Oegema K. PMID: 17488632.
      View in: PubMed   Mentions: 62     Fields:    Translation:Animals
    69. A microtubule-independent role for centrosomes and aurora a in nuclear envelope breakdown. Dev Cell. 2007 Apr; 12(4):515-29. Portier N, Audhya A, Maddox PS, Green RA, Dammermann A, Desai A, Oegema K. PMID: 17419991.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    70. Functional genomics identifies a Myb domain-containing protein family required for assembly of CENP-A chromatin. J Cell Biol. 2007 Mar 12; 176(6):757-63. Maddox PS, Hyndman F, Monen J, Oegema K, Desai A. PMID: 17339379.
      View in: PubMed   Mentions: 101     Fields:    Translation:AnimalsCells
    71. The C. elegans RSA complex localizes protein phosphatase 2A to centrosomes and regulates mitotic spindle assembly. Cell. 2007 Jan 12; 128(1):115-27. Schlaitz AL, Srayko M, Dammermann A, Quintin S, Wielsch N, MacLeod I, de Robillard Q, Zinke A, Yates JR, Müller-Reichert T, Shevchenko A, Oegema K, Hyman AA. PMID: 17218259.
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    72. Katanin controls mitotic and meiotic spindle length. J Cell Biol. 2006 Dec 18; 175(6):881-91. McNally K, Audhya A, Oegema K, McNally FJ. PMID: 17178907.
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    73. A Bir1-Sli15 complex connects centromeres to microtubules and is required to sense kinetochore tension. Cell. 2006 Dec 15; 127(6):1179-91. Sandall S, Severin F, McLeod IX, Yates JR, Oegema K, Hyman A, Desai A. PMID: 17174893.
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    74. Molecular analysis of mitotic chromosome condensation using a quantitative time-resolved fluorescence microscopy assay. Proc Natl Acad Sci U S A. 2006 Oct 10; 103(41):15097-102. Maddox PS, Portier N, Desai A, Oegema K. PMID: 17005720.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    75. Identification of novel chondroitin proteoglycans in Caenorhabditis elegans: embryonic cell division depends on CPG-1 and CPG-2. J Cell Biol. 2006 Jun 19; 173(6):985-94. Olson SK, Bishop JR, Yates JR, Oegema K, Esko JD. PMID: 16785326.
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    76. Dynamic regulation of caveolin-1 trafficking in the germ line and embryo of Caenorhabditis elegans. Mol Biol Cell. 2006 Jul; 17(7):3085-94. Sato K, Sato M, Audhya A, Oegema K, Schweinsberg P, Grant BD. PMID: 16672374.
      View in: PubMed   Mentions: 52     Fields:    Translation:AnimalsCells
    77. Cell division. WormBook. 2006 Jan 19; 1-40. Oegema K, Hyman AA. PMID: 18050484.
      View in: PubMed   Mentions: 49     Fields:    Translation:HumansAnimalsCells
    78. Differential role of CENP-A in the segregation of holocentric C. elegans chromosomes during meiosis and mitosis. Nat Cell Biol. 2005 Dec; 7(12):1248-55. Monen J, Maddox PS, Hyndman F, Oegema K, Desai A. PMID: 16273096.
      View in: PubMed   Mentions: 81     Fields:    Translation:AnimalsCells
    79. A complex containing the Sm protein CAR-1 and the RNA helicase CGH-1 is required for embryonic cytokinesis in Caenorhabditis elegans. J Cell Biol. 2005 Oct 24; 171(2):267-79. Audhya A, Hyndman F, McLeod IX, Maddox AS, Yates JR, Desai A, Oegema K. PMID: 16247027.
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    80. Distinct roles for two C. elegans anillins in the gonad and early embryo. Development. 2005 Jun; 132(12):2837-48. Maddox AS, Habermann B, Desai A, Oegema K. PMID: 15930113.
      View in: PubMed   Mentions: 62     Fields:    Translation:AnimalsCells
    81. The CENP-F-like proteins HCP-1 and HCP-2 target CLASP to kinetochores to mediate chromosome segregation. Curr Biol. 2005 Apr 26; 15(8):771-7. Cheeseman IM, MacLeod I, Yates JR, Oegema K, Desai A. PMID: 15854912.
      View in: PubMed   Mentions: 38     Fields:    Translation:AnimalsCells
    82. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec; 7(6):815-29. Dammermann A, Müller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. PMID: 15572125.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    83. A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev. 2004 Sep 15; 18(18):2255-68. Cheeseman IM, Niessen S, Anderson S, Hyndman F, Yates JR, Oegema K, Desai A. PMID: 15371340.
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    84. "Holo"er than thou: chromosome segregation and kinetochore function in C. elegans. Chromosome Res. 2004; 12(6):641-53. Maddox PS, Oegema K, Desai A, Cheeseman IM. PMID: 15289669.
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    85. KNL-1 directs assembly of the microtubule-binding interface of the kinetochore in C. elegans. Genes Dev. 2003 Oct 01; 17(19):2421-35. Desai A, Rybina S, Müller-Reichert T, Shevchenko A, Shevchenko A, Hyman A, Oegema K. PMID: 14522947.
      View in: PubMed   Mentions: 111     Fields:    Translation:AnimalsCells
    86. Deconstructing cytokinesis. Nat Cell Biol. 2003 Sep; 5(9):773-6. Maddox AS, Oegema K. PMID: 12951607.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    87. The minus end in sight. Curr Biol. 2003 Aug 05; 13(15):R614-24. Dammermann A, Desai A, Oegema K. PMID: 12906817.
      View in: PubMed   Mentions: 50     Fields:    Translation:Cells
    88. Closing the GAP: a role for a RhoA GAP in cytokinesis. Mol Cell. 2003 Apr; 11(4):846-8. Maddox AS, Oegema K. PMID: 12718869.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    89. SAS-4 is a C. elegans centriolar protein that controls centrosome size. Cell. 2003 Feb 21; 112(4):575-87. Kirkham M, Müller-Reichert T, Oegema K, Grill S, Hyman AA. PMID: 12600319.
      View in: PubMed   Mentions: 126     Fields:    Translation:AnimalsCells
    90. Poleward microtubule flux is a major component of spindle dynamics and anaphase a in mitotic Drosophila embryos. Curr Biol. 2002 Oct 01; 12(19):1670-4. Maddox P, Desai A, Oegema K, Mitchison TJ, Salmon ED. PMID: 12361570.
      View in: PubMed   Mentions: 36     Fields:    Translation:AnimalsCells
    91. The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent. J Cell Biol. 2002 May 13; 157(4):591-602. Hannak E, Oegema K, Kirkham M, Gönczy P, Habermann B, Hyman AA. PMID: 12011109.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    92. The gene encoding ARS-binding factor I is essential for the viability of yeast. Genes Dev. 1989 Dec; 3(12A):1926-39. Rhode PR, Sweder KS, Oegema KF, Campbell JL. PMID: 2620828.
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