Andrew Shiau

Title(s)Adjunct Professor, Cell and Developmental Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Control of cell proliferation by memories of mitosis. Science. 2024 Mar 29; 383(6690):1441-1448. Meitinger F, Belal H, Davis RL, Martinez MB, Shiau AK, Oegema K, Desai A. PMID: 38547292.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    2. Identification of a Small Molecule Inhibitor of Hyaluronan Synthesis, DDIT, Targeting Breast Cancer Cells. Cancers (Basel). 2022 Nov 25; 14(23). Karalis T, Shiau AK, Gahman TC, Skandalis SS, Heldin CH, Heldin P. PMID: 36497283.
      View in: PubMed   Mentions:
    3. The N-terminal tail of C. elegans CENP-A interacts with KNL-2 and is essential for centromeric chromatin assembly. Mol Biol Cell. 2021 06 01; 32(12):1193-1201. de Groot C, Houston J, Davis B, Gerson-Gurwitz A, Monen J, Lara-Gonzalez P, Oegema K, Shiau AK, Desai A. PMID: 33852350; PMCID: PMC8351560.
      View in: PubMed   Mentions: 4     Fields:    Translation:AnimalsCells
    4. Comprehensive analysis of single cell ATAC-seq data with SnapATAC. Nat Commun. 2021 02 26; 12(1):1337. Fang R, Preissl S, Li Y, Hou X, Lucero J, Wang X, Motamedi A, Shiau AK, Zhou X, Xie F, Mukamel EA, Zhang K, Zhang Y, Behrens MM, Ecker JR, Ren B. PMID: 33637727; PMCID: PMC7910485.
      View in: PubMed   Mentions: 148     Fields:    Translation:AnimalsCells
    5. Centriole-independent mitotic spindle assembly relies on the PCNT-CDK5RAP2 pericentriolar matrix. J Cell Biol. 2020 12 07; 219(12). Watanabe S, Meitinger F, Shiau AK, Oegema K, Desai A. PMID: 33170211; PMCID: PMC7658699.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansCells
    6. TRIM37 controls cancer-specific vulnerability to PLK4 inhibition. Nature. 2020 09; 585(7825):440-446. Meitinger F, Ohta M, Lee KY, Watanabe S, Davis RL, Anzola JV, Kabeche R, Jenkins DA, Shiau AK, Desai A, Oegema K. PMID: 32908304; PMCID: PMC7501188.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    7. Structure of LRRK2 in Parkinson's disease and model for microtubule interaction. Nature. 2020 12; 588(7837):344-349. Deniston CK, Salogiannis J, Mathea S, Snead DM, Lahiri I, Matyszewski M, Donosa O, Watanabe R, Böhning J, Shiau AK, Knapp S, Villa E, Reck-Peterson SL, Leschziner AE. PMID: 32814344; PMCID: PMC7726071.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    8. A Non-canonical BRCT-Phosphopeptide Recognition Mechanism Underlies RhoA Activation in Cytokinesis. Curr Biol. 2020 08 17; 30(16):3101-3115.e11. Gómez-Cavazos JS, Lee KY, Lara-González P, Li Y, Desai A, Shiau AK, Oegema K. PMID: 32619481; PMCID: PMC7438317.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    9. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 Dec 09; 36(6):690-691. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 31821785; PMCID: PMC6946119.
      View in: PubMed   Mentions: 10     Fields:    
    10. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 May 13; 35(5):816. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 31085179; PMCID: PMC8717880.
      View in: PubMed   Mentions: 10     Fields:    
    11. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 2019 03 18; 35(3):504-518.e7. Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, Gahman TC, Shiau AK, Zhou H, DeGroot J, Sulman EP, Cavenee WK, Kolodner RD, Chen CC, Furnari FB. PMID: 30827889; PMCID: PMC6424615.
      View in: PubMed   Mentions: 60     Fields:    Translation:HumansAnimalsCells
    12. Differential effect of inhibitory strategies of the V617 mutant of JAK2 on cytokine receptor signaling. J Allergy Clin Immunol. 2019 07; 144(1):224-235. Leroy E, Balligand T, Pecquet C, Mouton C, Colau D, Shiau AK, Dusa A, Constantinescu SN. PMID: 30707971.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    13. CFI-400945 is not a selective cellular PLK4 inhibitor. Proc Natl Acad Sci U S A. 2018 11 13; 115(46):E10808-E10809. Oegema K, Davis RL, Lara-Gonzalez P, Desai A, Shiau AK. PMID: 30377272; PMCID: PMC6243232.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    14. Phenotypic Screening for Inhibitors of a Mutant Thrombopoietin Receptor. Methods Mol Biol. 2018; 1787:53-66. Ngo A, Koay A, Pecquet C, Diaconu CC, Jenkins DA, Shiau AK, Constantinescu SN, Choong ML. PMID: 29736709.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    15. Identification of H3K4me1-associated proteins at mammalian enhancers. Nat Genet. 2018 01; 50(1):73-82. Local A, Huang H, Albuquerque CP, Singh N, Lee AY, Wang W, Wang C, Hsia JE, Shiau AK, Ge K, Corbett KD, Wang D, Zhou H, Ren B. PMID: 29255264; PMCID: PMC6007000.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    16. mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Mol Cell. 2017 Jul 06; 67(1):128-138.e7. Gu Y, Albuquerque CP, Braas D, Zhang W, Villa GR, Bi J, Ikegami S, Masui K, Gini B, Yang H, Gahman TC, Shiau AK, Cloughesy TF, Christofk HR, Zhou H, Guan KL, Mischel PS. PMID: 28648777; PMCID: PMC5521991.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansCells
    17. Glioblastoma cellular cross-talk converges on NF-κB to attenuate EGFR inhibitor sensitivity. Genes Dev. 2017 06 15; 31(12):1212-1227. Zanca C, Villa GR, Benitez JA, Thorne AH, Koga T, D'Antonio M, Ikegami S, Ma J, Boyer AD, Banisadr A, Jameson NM, Parisian AD, Eliseeva OV, Barnabe GF, Liu F, Wu S, Yang H, Wykosky J, Frazer KA, Verkhusha VV, Isaguliants MG, Weiss WA, Gahman TC, Shiau AK, Chen CC, Mischel PS, Cavenee WK, Furnari FB. PMID: 28724615; PMCID: PMC5558924.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    18. An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers. Cancer Cell. 2016 Nov 14; 30(5):683-693. Villa GR, Hulce JJ, Zanca C, Bi J, Ikegami S, Cahill GL, Gu Y, Lum KM, Masui K, Yang H, Rong X, Hong C, Turner KM, Liu F, Hon GC, Jenkins D, Martini M, Armando AM, Quehenberger O, Cloughesy TF, Furnari FB, Cavenee WK, Tontonoz P, Gahman TC, Shiau AK, Cravatt BF, Mischel PS. PMID: 27746144; PMCID: PMC5479636.
      View in: PubMed   Mentions: 157     Fields:    Translation:HumansAnimalsCells
    19. GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge. Mol Biol Cell. 2016 12 01; 27(24):3828-3840. Xing M, Peterman MC, Davis RL, Oegema K, Shiau AK, Field SJ. PMID: 27708138; PMCID: PMC5170606.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    20. Chemical regulators of epithelial plasticity reveal a nuclear receptor pathway controlling myofibroblast differentiation. Sci Rep. 2016 07 19; 6:29868. Carthy JM, Stöter M, Bellomo C, Vanlandewijck M, Heldin A, Morén A, Kardassis D, Gahman TC, Shiau AK, Bickle M, Zerial M, Heldin CH, Moustakas A. PMID: 27430378; PMCID: PMC4949434.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    21. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016 07 18; 214(2):155-66. Meitinger F, Anzola JV, Kaulich M, Richardson A, Stender JD, Benner C, Glass CK, Dowdy SF, Desai A, Shiau AK, Oegema K. PMID: 27432897; PMCID: PMC4949453.
      View in: PubMed   Mentions: 103     Fields:    Translation:HumansCells
    22. Uncoupling JAK2 V617F activation from cytokine-induced signalling by modulation of JH2 αC helix. Biochem J. 2016 06 01; 473(11):1579-91. Leroy E, Dusa A, Colau D, Motamedi A, Cahu X, Mouton C, Huang LJ, Shiau AK, Constantinescu SN. PMID: 27029346; PMCID: PMC4888464.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    23. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Mol Cancer Ther. 2016 06; 15(6):1217-26. Tögel L, Nightingale R, Chueh AC, Jayachandran A, Tran H, Phesse T, Wu R, Sieber OM, Arango D, Dhillon AS, Dawson MA, Diez-Dacal B, Gahman TC, Filippakopoulos P, Shiau AK, Mariadason JM. PMID: 26983878.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    24. A Phenotypic Screen for Small-Molecule Inhibitors of Constitutively Active Mutant Thrombopoietin Receptor Implicated in Myeloproliferative Neoplasms. Comb Chem High Throughput Screen. 2016; 19(10):824-833. Ngo A, Koay AZ, Pecquet C, Diaconu CC, Ould-Amer Y, Huang Q, Kang C, Poulsen A, Lee MA, Jenkins D, Shiau A, Constantinescu SN, Choong ML. PMID: 27748177.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    25. A Cell Biologist's Field Guide to Aurora Kinase Inhibitors. Front Oncol. 2015; 5:285. de Groot CO, Hsia JE, Anzola JV, Motamedi A, Yoon M, Wong YL, Jenkins D, Lee HJ, Martinez MB, Davis RL, Gahman TC, Desai A, Shiau AK. PMID: 26732741; PMCID: PMC4685510.
      View in: PubMed   Mentions: 43  
    26. EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling. Mol Cell. 2015 Oct 15; 60(2):307-18. Liu F, Hon GC, Villa GR, Turner KM, Ikegami S, Yang H, Ye Z, Li B, Kuan S, Lee AY, Zanca C, Wei B, Lucey G, Jenkins D, Zhang W, Barr CL, Furnari FB, Cloughesy TF, Yong WH, Gahman TC, Shiau AK, Cavenee WK, Ren B, Mischel PS. PMID: 26455392; PMCID: PMC4609298.
      View in: PubMed   Mentions: 100     Fields:    Translation:HumansAnimalsCells
    27. Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation. Cell Rep. 2015 Jul 07; 12(1):58-65. Espeut J, Lara-Gonzalez P, Sassine M, Shiau AK, Desai A, Abrieu A. PMID: 26119738; PMCID: PMC4668945.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansAnimalsCells
    28. Cell biology. Reversible centriole depletion with an inhibitor of Polo-like kinase 4. Science. 2015 Jun 05; 348(6239):1155-60. Wong YL, Anzola JV, Davis RL, Yoon M, Motamedi A, Kroll A, Seo CP, Hsia JE, Kim SK, Mitchell JW, Mitchell BJ, Desai A, Gahman TC, Shiau AK, Oegema K. PMID: 25931445; PMCID: PMC4764081.
      View in: PubMed   Mentions: 227     Fields:    Translation:HumansAnimalsCells
    29. Common regulatory control of CTP synthase enzyme activity and filament formation. Mol Biol Cell. 2014 Aug 01; 25(15):2282-90. Noree C, Monfort E, Shiau AK, Wilhelm JE. PMID: 24920825; PMCID: PMC4116302.
      View in: PubMed   Mentions: 53     Fields:    Translation:AnimalsCells
    30. Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Dev Cell. 2013 May 13; 25(3):284-98. Lettman MM, Wong YL, Viscardi V, Niessen S, Chen SH, Shiau AK, Zhou H, Desai A, Oegema K. PMID: 23673331; PMCID: PMC3655416.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    31. Discovery and optimization of a series of liver X receptor antagonists. Bioorg Med Chem Lett. 2012 Sep 15; 22(18):5966-70. Jiao X, Kopecky DJ, Fisher B, Piper DE, Labelle M, McKendry S, Harrison M, Jones S, Jaen J, Shiau AK, Escaron P, Danao J, Chai A, Coward P, Kayser F. PMID: 22901900.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    32. SU-E-T-233: Evaluation of Superficial Doses for Postmastectomy Radiotherapy. Med Phys. 2012 Jun; 39(6Part13):3757. Shiau A, Chiu M, Chen T, Chiou J, Shueng P, Chen S, Chen W, Kuan W. PMID: 28517303.
      View in: PubMed   Mentions: 1     Fields:    
    33. Discovery of a new binding mode for a series of liver X receptor agonists. Bioorg Med Chem Lett. 2012 Apr 01; 22(7):2407-10. Kopecky DJ, Jiao XY, Fisher B, McKendry S, Labelle M, Piper DE, Coward P, Shiau AK, Escaron P, Danao J, Chai A, Jaen J, Kayser F. PMID: 22406115.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    34. Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors. Bioorg Med Chem Lett. 2012 Jan 15; 22(2):1237-41. Durón SG, Lindstrom A, Bonnefous C, Zhang H, Chen X, Symons KT, Sablad M, Rozenkrants N, Zhang Y, Wang L, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND. PMID: 22182498.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    35. Identification and SAR of selective inducible nitric oxide synthase (iNOS) dimerization inhibitors. Bioorg Med Chem Lett. 2011 Nov 15; 21(22):6888-94. Gahman TC, Herbert MR, Lang H, Thayer A, Symons KT, Nguyen PM, Massari ME, Dozier S, Zhang Y, Sablad M, Rao TS, Noble SA, Shiau AK, Hassig CA. PMID: 21986586.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    36. Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNOS dimerization inhibitors that are orally active in pain models. J Med Chem. 2010 Nov 11; 53(21):7739-55. Payne JE, Bonnefous C, Symons KT, Nguyen PM, Sablad M, Rozenkrants N, Zhang Y, Wang L, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND. PMID: 20931971.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    37. Pharmacological characterization of KLYP961, a dual inhibitor of inducible and neuronal nitric-oxide synthases. J Pharmacol Exp Ther. 2011 Feb; 336(2):468-78. Symons KT, Nguyen PM, Massari ME, Anzola JV, Staszewski LM, Wang L, Yazdani N, Dorow S, Muhammad J, Sablad M, Rozenkrants N, Bonefous C, Payne JE, Rix PJ, Shiau AK, Noble SA, Smith ND, Hassig CA, Zhang Y, Rao TS. PMID: 21036913.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    38. Synthesis and SAR of 2-aryl-3-aminomethylquinolines as agonists of the bile acid receptor TGR5. Bioorg Med Chem Lett. 2010 Oct 01; 20(19):5718-21. Herbert MR, Siegel DL, Staszewski L, Cayanan C, Banerjee U, Dhamija S, Anderson J, Fan A, Wang L, Rix P, Shiau AK, Rao TS, Noble SA, Heyman RA, Bischoff E, Guha M, Kabakibi A, Pinkerton AB. PMID: 20801037.
      View in: PubMed   Mentions: 16     Fields:    Translation:Animals
    39. Benzothiophene containing Rho kinase inhibitors: Efficacy in an animal model of glaucoma. Bioorg Med Chem Lett. 2010 Jun 01; 20(11):3361-6. Davis RL, Kahraman M, Prins TJ, Beaver Y, Cook TG, Cramp J, Cayanan CS, Gardiner EM, McLaughlin MA, Clark AF, Hellberg MR, Shiau AK, Noble SA, Borchardt AJ. PMID: 20434334.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    40. Water-soluble PDE4 inhibitors for the treatment of dry eye. Bioorg Med Chem Lett. 2010 May 01; 20(9):2928-32. Govek SP, Oshiro G, Anzola JV, Beauregard C, Chen J, Coyle AR, Gamache DA, Hellberg MR, Hsien JN, Lerch JM, Liao JC, Malecha JW, Staszewski LM, Thomas DJ, Yanni JM, Noble SA, Shiau AK. PMID: 20378348.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    41. Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models. J Med Chem. 2009 May 14; 52(9):3047-62. Bonnefous C, Payne JE, Roppe J, Zhuang H, Chen X, Symons KT, Nguyen PM, Sablad M, Rozenkrants N, Zhang Y, Wang L, Severance D, Walsh JP, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND. PMID: 19374401.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    42. KLYP956 is a non-imidazole-based orally active inhibitor of nitric-oxide synthase dimerization. Mol Pharmacol. 2009 Jul; 76(1):153-62. Symons KT, Massari ME, Nguyen PM, Lee TT, Roppe J, Bonnefous C, Payne JE, Smith ND, Noble SA, Sablad M, Rozenkrants N, Zhang Y, Rao TS, Shiau AK, Hassig CA. PMID: 19364813.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    43. Identification of KD5170: a novel mercaptoketone-based histone deacetylase inhibitor. Bioorg Med Chem Lett. 2008 Dec 01; 18(23):6093-6. Payne JE, Bonnefous C, Hassig CA, Symons KT, Guo X, Nguyen PM, Annable T, Wash PL, Hoffman TZ, Rao TS, Shiau AK, Malecha JW, Noble SA, Hager JH, Smith ND. PMID: 18954983.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    44. Inhibition of inducible nitric oxide synthase expression by a novel small molecule activator of the unfolded protein response. Curr Chem Genomics. 2008 Sep 27; 2:1-9. Symons KT, Massari ME, Dozier SJ, Nguyen PM, Jenkins D, Herbert M, Gahman TC, Noble SA, Rozenkrants N, Zhang Y, Rao TS, Shiau AK, Hassig CA. PMID: 20161838; PMCID: PMC2803434.
      View in: PubMed   Mentions:
    45. KD5170, a novel mercaptoketone-based histone deacetylase inhibitor that exhibits broad spectrum antitumor activity in vitro and in vivo. Mol Cancer Ther. 2008 May; 7(5):1054-65. Hassig CA, Symons KT, Guo X, Nguyen PM, Annable T, Wash PL, Payne JE, Jenkins DA, Bonnefous C, Trotter C, Wang Y, Anzola JV, Milkova EL, Hoffman TZ, Dozier SJ, Wiley BM, Saven A, Malecha JW, Davis RL, Muhammad J, Shiau AK, Noble SA, Rao TS, Smith ND, Hager JH. PMID: 18483295.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    46. Back to basics: label-free technologies for small molecule screening. Comb Chem High Throughput Screen. 2008 Mar; 11(3):231-7. Shiau AK, Massari ME, Ozbal CC. PMID: 18336215.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansAnimals
    47. Synthesis and SAR of thiophene containing kinesin spindle protein (KSP) inhibitors. Bioorg Med Chem Lett. 2007 Jul 01; 17(13):3562-9. Pinkerton AB, Lee TT, Hoffman TZ, Wang Y, Kahraman M, Cook TG, Severance D, Gahman TC, Noble SA, Shiau AK, Davis RL. PMID: 17498954.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    48. Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements. Cell. 2006 Oct 20; 127(2):329-40. Shiau AK, Harris SF, Southworth DR, Agard DA. PMID: 17055434.
      View in: PubMed   Mentions: 217     Fields:    Translation:Cells
    49. The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site. Structure. 2004 Jun; 12(6):1087-97. Harris SF, Shiau AK, Agard DA. PMID: 15274928.
      View in: PubMed   Mentions: 79     Fields:    Translation:Cells
    50. A structural explanation for ERalpha/ERbeta SERM discrimination. Ernst Schering Res Found Workshop. 2004; (46):33-45. Greene GL, Shiau AK, Nettles KW. PMID: 15248503.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    51. Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism. Nat Struct Biol. 2002 May; 9(5):359-64. Shiau AK, Barstad D, Radek JT, Meyers MJ, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA, Agard DA, Greene GL. PMID: 11953755.
      View in: PubMed   Mentions: 79     Fields:    Translation:HumansCells
    52. Orphan nuclear receptors: from new ligand discovery technologies to novel signaling pathways. Curr Opin Drug Discov Devel. 2001 Sep; 4(5):575-90. Shiau AK, Coward P, Schwarz M, Lehmann JM. PMID: 12825453.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    53. Hormone selectivity in thyroid hormone receptors. Mol Endocrinol. 2001 Mar; 15(3):398-410. Wagner RL, Huber BR, Shiau AK, Kelly A, Cunha Lima ST, Scanlan TS, Apriletti JW, Baxter JD, West BL, Fletterick RJ. PMID: 11222741.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansCells
    54. Estrogen receptor pathways to AP-1. J Steroid Biochem Mol Biol. 2000 Nov 30; 74(5):311-7. Kushner PJ, Agard DA, Greene GL, Scanlan TS, Shiau AK, Uht RM, Webb P. PMID: 11162939.
      View in: PubMed   Mentions: 264     Fields:    Translation:HumansAnimalsCells
    55. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell. 1998 Dec 23; 95(7):927-37. Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA, Greene GL. PMID: 9875847.
      View in: PubMed   Mentions: 582     Fields:    Translation:HumansAnimalsCells
    56. Pro region C-terminus:protease active site interactions are critical in catalyzing the folding of alpha-lytic protease. Biochemistry. 1998 Sep 01; 37(35):12058-67. Peters RJ, Shiau AK, Sohl JL, Anderson DE, Tang G, Silen JL, Agard DA. PMID: 9724517.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    57. Inhibition of alpha-lytic protease by pro region C-terminal steric occlusion of the active site. Biochemistry. 1997 Apr 01; 36(13):3894-902. Sohl JL, Shiau AK, Rader SD, Wilk BJ, Agard DA. PMID: 9092819.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    58. Determinants of performance in the isocitrate dehydrogenase of Escherichia coli. Protein Sci. 1996 Feb; 5(2):341-7. Dean AM, Shiau AK, Koshland DE. PMID: 8745412; PMCID: PMC2143340.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    59. P2U purinoceptors: cDNA cloning, signal transduction mechanisms and structure-function analysis. Ciba Found Symp. 1996; 198:193-204; discussion 204-7. Lustig KD, Weisman GA, Turner JT, Garrad R, Shiau AK, Erb L. PMID: 8879826.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    60. A phage display system for studying the sequence determinants of protein folding. Protein Sci. 1995 Jun; 4(6):1108-17. Gu H, Yi Q, Bray ST, Riddle DS, Shiau AK, Baker D. PMID: 7549875; PMCID: PMC2143147.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    61. Serum retinoic acid levels in patients with resected benign and malignant colonic neoplasias on beta-carotene supplementation. Nutr Cancer. 1995; 23(3):291-8. Tang G, Shiau A, Russell RM, Mobarhan S. PMID: 7603889.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    62. The role of pro regions in protein folding. Curr Opin Cell Biol. 1993 Dec; 5(6):966-70. Baker D, Shiau AK, Agard DA. PMID: 8129949.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    63. Trypsin display on the surface of bacteriophage. Gene. 1993 Jun 15; 128(1):129-34. Corey DR, Shiau AK, Yang Q, Janowski BA, Craik CS. PMID: 8508953.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    64. Expression cloning of an ATP receptor from mouse neuroblastoma cells. Proc Natl Acad Sci U S A. 1993 Jun 01; 90(11):5113-7. Lustig KD, Shiau AK, Brake AJ, Julius D. PMID: 7685114; PMCID: PMC46665.
      View in: PubMed   Mentions: 162     Fields:    Translation:HumansAnimalsCells
    65. Genes of the Escherichia coli pur regulon are negatively controlled by a repressor-operator interaction. J Bacteriol. 1990 Aug; 172(8):4555-62. He B, Shiau A, Choi KY, Zalkin H, Smith JM. PMID: 2198266; PMCID: PMC213288.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    66. Subcloning, characterization, and affinity labeling of Escherichia coli glycinamide ribonucleotide transformylase. Biochemistry. 1990 Feb 13; 29(6):1436-43. Inglese J, Johnson DL, Shiau A, Smith JM, Benkovic SJ. PMID: 2185839.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    67. Formylglycinamide ribonucleotide synthetase from Escherichia coli: cloning, sequencing, overproduction, isolation, and characterization. Biochemistry. 1989 Mar 21; 28(6):2459-71. Schendel FJ, Mueller E, Stubbe J, Shiau A, Smith JM. PMID: 2659070.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    68. Improved cat gene cassette for promoter analysis and genetic constructions. Gene. 1988 Jul 30; 67(2):295-9. Shiau A, Smith JM. PMID: 3169577.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
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