Loading...

Brendan Duggan

Title(s)Project Scientist, School of Pharmacy and Pharmaceutical Science
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #0684
La Jolla CA 92093
Phone8/5-34--8763
ORCID ORCID Icon0000-0002-7034-8374 Additional info
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    Monash University, Parkville VIC AustraliaPh.D.1996Physical Biochemistry

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Featured Publications
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Commensal Oral Rothia mucilaginosa Produces Enterobactin, a Metal-Chelating Siderophore. mSystems. 2020 Apr 28; 5(2). Uranga CC, Arroyo P, Duggan BM, Gerwick WH, Edlund A. PMID: 32345739.
      View in: PubMed   Mentions:
    2. Corrigendum: Searching for Small Molecules with an Atomic Sort. Angew Chem Int Ed Engl. 2020 Mar 23; 59(13):4993. Duggan BM, Cullum R, Fenical W, Amador LA, Rodríguez AD, La Clair JJ. PMID: 32175689.
      View in: PubMed   Mentions:    Fields:    
    3. Author Correction: Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research. Sci Rep. 2020 Mar 10; 10(1):4724. Zhang C, Idelbayev Y, Roberts N, Tao Y, Nannapaneni Y, Duggan BM, Min J, Lin EC, Gerwick EC, Cottrell GW, Gerwick WH. PMID: 32152329.
      View in: PubMed   Mentions:    Fields:    
    4. A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products. J Am Chem Soc. 2020 Mar 04; 142(9):4114-4120. Reher R, Kim HW, Zhang C, Mao HH, Wang M, Nothias LF, Caraballo-Rodriguez AM, Glukhov E, Teke B, Leao T, Alexander KL, Duggan BM, Van Everbroeck EL, Dorrestein PC, Cottrell GW, Gerwick WH. PMID: 32045230.
      View in: PubMed   Mentions: 4     Fields:    
    5. The Pierced Lasso Topology Leptin has a Bolt on Dynamic Domain Composed by the Disordered Loops I and III. J Mol Biol. 2020 Apr 17; 432(9):3050-3063. Danielsson J, Noel JK, Simien JM, Duggan BM, Oliveberg M, Onuchic JN, Jennings PA, Haglund E. PMID: 32081588.
      View in: PubMed   Mentions:    Fields:    
    6. Tutuilamides A-C: Vinyl-Chloride-Containing Cyclodepsipeptides from Marine Cyanobacteria with Potent Elastase Inhibitory Properties. ACS Chem Biol. 2020 03 20; 15(3):751-757. Keller L, Canuto KM, Liu C, Suzuki BM, Almaliti J, Sikandar A, Naman CB, Glukhov E, Luo D, Duggan BM, Luesch H, Koehnke J, O'Donoghue AJ, Gerwick WH. PMID: 31935054.
      View in: PubMed   Mentions: 2     Fields:    
    7. Editorial to the Special Issue-"Technology for Natural Products Research". Molecules. 2020 Jan 14; 25(2). Duggan BM. PMID: 31947506.
      View in: PubMed   Mentions:    Fields:    
    8. Searching for Small Molecules with an Atomic Sort. Angew Chem Int Ed Engl. 2020 01 13; 59(3):1144-1148. Duggan BM, Cullum R, Fenical W, Amador LA, Rodríguez AD, La Clair JJ. PMID: 31696595.
      View in: PubMed   Mentions:    Fields:    
    9. Synthesis, Pharmacological Characterization, and Structure-Activity Relationships of Noncanonical Selective Agonists for a7 nAChRs. J Med Chem. 2019 11 27; 62(22):10376-10390. Camacho-Hernandez GA, Stokes C, Duggan BM, Kaczanowska K, Brandao-Araiza S, Doan L, Papke RL, Taylor P. PMID: 31675224.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    10. Lepadins I-K, 3- O-(3'-Methylthio)acryloyloxy-decahydroquinoline Esters from a Bahamian Ascidian Didemnum sp. Assignment of Absolute Stereostructures. J Org Chem. 2018 11 16; 83(22):13670-13677. Ómarsdóttir S, Wang X, Liu HB, Duggan BM, Molinski TF. PMID: 30280573.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    11. Identification of a 3-Alkylpyridinium Compound from the Red Sea Sponge Amphimedon chloros with In Vitro Inhibitory Activity against the West Nile Virus NS3 Protease. Molecules. 2018 06 18; 23(6). O'Rourke A, Kremb S, Duggan BM, Sioud S, Kharbatia N, Raji M, Emwas AH, Gerwick WH, Voolstra CR. PMID: 29912151.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    12. Small Molecule Accurate Recognition Technology (SMART) to Enhance Natural Products Research. Sci Rep. 2017 10 27; 7(1):14243. Zhang C, Idelbayev Y, Roberts N, Tao Y, Nannapaneni Y, Duggan BM, Min J, Lin EC, Gerwick EC, Cottrell GW, Gerwick WH. PMID: 29079836.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    13. Digitizing mass spectrometry data to explore the chemical diversity and distribution of marine cyanobacteria and algae. Elife. 2017 05 11; 6. Luzzatto-Knaan T, Garg N, Wang M, Glukhov E, Peng Y, Ackermann G, Amir A, Duggan BM, Ryazanov S, Gerwick L, Knight R, Alexandrov T, Bandeira N, Gerwick WH, Dorrestein PC. PMID: 28492366.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    14. Higher heritabilities for gait components than for overall gait scores may improve mobility in ducks. Genet Sel Evol. 2017 05 02; 49(1):42. Duggan BM, Rae AM, Clements DN, Hocking PM. PMID: 28464791.
      View in: PubMed   Mentions: 2     Fields:    Translation:Animals
    15. Erratum: Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nat Microbiol. 2017 Jan 23; 2:17010. Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC. PMID: 28112718.
      View in: PubMed   Mentions: 1     Fields:    
    16. Indexing the Pseudomonas specialized metabolome enabled the discovery of poaeamide B and the bananamides. Nat Microbiol. 2016 10 31; 2:16197. Nguyen DD, Melnik AV, Koyama N, Lu X, Schorn M, Fang J, Aguinaldo K, Lincecum TL, Ghequire MG, Carrion VJ, Cheng TL, Duggan BM, Malone JG, Mauchline TH, Sanchez LM, Kilpatrick AM, Raaijmakers JM, De Mot R, Moore BS, Medema MH, Dorrestein PC. PMID: 27798598.
      View in: PubMed   Mentions: 18     Fields:    Translation:AnimalsCells
    17. Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin. Nat Chem Biol. 2016 10; 12(10):773-5. Li ZR, Li J, Gu JP, Lai JY, Duggan BM, Zhang WP, Li ZL, Li YX, Tong RB, Xu Y, Lin DH, Moore BS, Qian PY. PMID: 27547923.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    18. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking. Nat Biotechnol. 2016 08 09; 34(8):828-837. Wang M, Carver JJ, Phelan VV, Sanchez LM, Garg N, Peng Y, Nguyen DD, Watrous J, Kapono CA, Luzzatto-Knaan T, Porto C, Bouslimani A, Melnik AV, Meehan MJ, Liu WT, Crüsemann M, Boudreau PD, Esquenazi E, Sandoval-Calderón M, Kersten RD, Pace LA, Quinn RA, Duncan KR, Hsu CC, Floros DJ, Gavilan RG, Kleigrewe K, Northen T, Dutton RJ, Parrot D, Carlson EE, Aigle B, Michelsen CF, Jelsbak L, Sohlenkamp C, Pevzner P, Edlund A, McLean J, Piel J, Murphy BT, Gerwick L, Liaw CC, Yang YL, Humpf HU, Maansson M, Keyzers RA, Sims AC, Johnson AR, Sidebottom AM, Sedio BE, Klitgaard A, Larson CB, P CAB, Torres-Mendoza D, Gonzalez DJ, Silva DB, Marques LM, Demarque DP, Pociute E, O'Neill EC, Briand E, Helfrich EJN, Granatosky EA, Glukhov E, Ryffel F, Houson H, Mohimani H, Kharbush JJ, Zeng Y, Vorholt JA, Kurita KL, Charusanti P, McPhail KL, Nielsen KF, Vuong L, Elfeki M, Traxler MF, Engene N, Koyama N, Vining OB, Baric R, Silva RR, Mascuch SJ, Tomasi S, Jenkins S, Macherla V, Hoffman T, Agarwal V, Williams PG, Dai J, Neupane R, Gurr J, Rodríguez AMC, Lamsa A, Zhang C, Dorrestein K, Duggan BM, Almaliti J, Allard PM, Phapale P, Nothias LF, Alexandrov T, Litaudon M, Wolfender JL, Kyle JE, Metz TO, Peryea T, Nguyen DT, VanLeer D, Shinn P, Jadhav A, Müller R, Waters KM, Shi W, Liu X, Zhang L, Knight R, Jensen PR, Palsson BO, Pogliano K, Linington RG, Gutiérrez M, Lopes NP, Gerwick WH, Moore BS, Dorrestein PC, Bandeira N. PMID: 27504778.
      View in: PubMed   Mentions: 231     Fields:    
    19. Ultra-high resolution band-selective HSQC for nanomole-scale identification of chlorine-substituted 13 C in natural products drug discovery. Magn Reson Chem. 2017 Apr; 55(4):263-268. Wang X, Duggan BM, Molinski TF. PMID: 26951950.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    20. The Alga Ochromonas danica Produces Bromosulfolipids. Org Lett. 2016 Mar 04; 18(5):1124-7. White AR, Duggan BM, Tsai SC, Vanderwal CD. PMID: 26889956.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    21. Efficient Red Light Photo-Uncaging of Active Molecules in Water Upon Assembly into Nanoparticles. Chem Sci. 2016 Mar; 7(3):2392-2398. Carling CJ, Olejniczak J, Foucault-Collet A, Collet G, Viger ML, Huu VA, Duggan BM, Almutairi A. PMID: 27014436.
      View in: PubMed   Mentions:
    22. Differences in hindlimb morphology of ducks and chickens: effects of domestication and selection. Genet Sel Evol. 2015 Nov 17; 47:88. Duggan BM, Hocking PM, Schwarz T, Clements DN. PMID: 26576729.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    23. Mollenynes B-E from the marine sponge Spirastrella mollis. Band-selective heteronuclear single quantum coherence for discrimination of bromo-chloro regioisomerism in natural products. J Am Chem Soc. 2015 Sep 30; 137(38):12343-51. Wang X, Duggan BM, Molinski TF. PMID: 26336030.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    24. Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria. J Nat Prod. 2015 Jul 24; 78(7):1671-82. Kleigrewe K, Almaliti J, Tian IY, Kinnel RB, Korobeynikov A, Monroe EA, Duggan BM, Di Marzo V, Sherman DH, Dorrestein PC, Gerwick L, Gerwick WH. PMID: 26149623.
      View in: PubMed   Mentions: 27     Fields:    Translation:Cells
    25. Detailed analysis of (-)-palmyrolide a and some synthetic derivatives as voltage-gated sodium channel antagonists. J Nat Prod. 2014 Nov 26; 77(11):2553-60. Mehrotra S, Duggan BM, Tello-Aburto R, Newar TD, Gerwick WH, Murray TF, Maio WA. PMID: 25343669.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    26. Glycogenomics as a mass spectrometry-guided genome-mining method for microbial glycosylated molecules. Proc Natl Acad Sci U S A. 2013 Nov 19; 110(47):E4407-16. Kersten RD, Ziemert N, Gonzalez DJ, Duggan BM, Nizet V, Dorrestein PC, Moore BS. PMID: 24191063.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    27. MS/MS-based networking and peptidogenomics guided genome mining revealed the stenothricin gene cluster in Streptomyces roseosporus. J Antibiot (Tokyo). 2014 Jan; 67(1):99-104. Liu WT, Lamsa A, Wong WR, Boudreau PD, Kersten R, Peng Y, Moree WJ, Duggan BM, Moore BS, Gerwick WH, Linington RG, Pogliano K, Dorrestein PC. PMID: 24149839.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    28. The arginine-rich RNA-binding motif of HIV-1 Rev is intrinsically disordered and folds upon RRE binding. Biophys J. 2013 Aug 20; 105(4):1004-17. Casu F, Duggan BM, Hennig M. PMID: 23972852.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    29. A distal mutation perturbs dynamic amino acid networks in dihydrofolate reductase. Biochemistry. 2013 Jul 09; 52(27):4605-19. Boehr DD, Schnell JR, McElheny D, Bae SH, Duggan BM, Benkovic SJ, Dyson HJ, Wright PE. PMID: 23758161.
      View in: PubMed   Mentions: 25     Fields:    
    30. MS/MS networking guided analysis of molecule and gene cluster families. Proc Natl Acad Sci U S A. 2013 Jul 09; 110(28):E2611-20. Nguyen DD, Wu CH, Moree WJ, Lamsa A, Medema MH, Zhao X, Gavilan RG, Aparicio M, Atencio L, Jackson C, Ballesteros J, Sanchez J, Watrous JD, Phelan VV, van de Wiel C, Kersten RD, Mehnaz S, De Mot R, Shank EA, Charusanti P, Nagarajan H, Duggan BM, Moore BS, Bandeira N, Palsson BØ, Pogliano K, Gutiérrez M, Dorrestein PC. PMID: 23798442.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    31. Bioactivity-guided genome mining reveals the lomaiviticin biosynthetic gene cluster in Salinispora tropica. Chembiochem. 2013 May 27; 14(8):955-62. Kersten RD, Lane AL, Nett M, Richter TK, Duggan BM, Dorrestein PC, Moore BS. PMID: 23649992.
      View in: PubMed   Mentions: 29     Fields:    Translation:Cells
    32. Catalytic detoxification of nerve agent and pesticide organophosphates by butyrylcholinesterase assisted with non-pyridinium oximes. Biochem J. 2013 Feb 15; 450(1):231-42. Radic Z, Dale T, Kovarik Z, Berend S, Garcia E, Zhang L, Amitai G, Green C, Radic B, Duggan BM, Ajami D, Rebek J, Taylor P. PMID: 23216060.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    33. Microbial metabolic exchange in 3D. ISME J. 2013 Apr; 7(4):770-80. Watrous JD, Phelan VV, Hsu CC, Moree WJ, Duggan BM, Alexandrov T, Dorrestein PC. PMID: 23283018.
      View in: PubMed   Mentions: 27     Fields:    Translation:AnimalsCells
    34. The energy expenditure of stair climbing one step and two steps at a time: estimations from measures of heart rate. PLoS One. 2012; 7(12):e51213. Halsey LG, Watkins DA, Duggan BM. PMID: 23251455.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    35. Interkingdom metabolic transformations captured by microbial imaging mass spectrometry. Proc Natl Acad Sci U S A. 2012 Aug 21; 109(34):13811-6. Moree WJ, Phelan VV, Wu CH, Bandeira N, Cornett DS, Duggan BM, Dorrestein PC. PMID: 22869730.
      View in: PubMed   Mentions: 77     Fields:    Translation:HumansAnimalsCells
    36. ¹H, ¹³C and ¹5N assignments of the holo-acyl carrier protein of Pseudomonas aeruginosa. Biomol NMR Assign. 2013 Oct; 7(2):225-8. Duggan BM, Roca A, Zhang YM. PMID: 22843382.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    37. NMR assignments of the N-terminal domain of Nephila clavipes spidroin 1. Biomol NMR Assign. 2011 Oct; 5(2):131-3. Parnham S, Gaines WA, Duggan BM, Marcotte WR, Hennig M. PMID: 21152998.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    38. Messenger RNAs under differential translational control in Ki-ras-transformed cells. Mol Cancer Res. 2006 Jan; 4(1):47-60. Spence J, Duggan BM, Eckhardt C, McClelland M, Mercola D. PMID: 16446406.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    39. E. coli selection of human genes encoding secreted and membrane proteins based on cDNA fusions to a leaderless beta-lactamase reporter. Genome Res. 2003 Aug; 13(8):1938-43. Tan R, Jiang X, Jackson A, Jin P, Yang J, Lee E, Duggan B, Stuve LL, Fu GK. PMID: 12869575.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    40. Potential bias in NMR relaxation data introduced by peak intensity analysis and curve fitting methods. J Biomol NMR. 2001 Sep; 21(1):1-9. Viles JH, Duggan BM, Zaborowski E, Schwarzinger S, Huntley JJ, Kroon GJ, Dyson HJ, Wright PE. PMID: 11693564.
      View in: PubMed   Mentions: 20     Fields:    
    41. SANE (Structure Assisted NOE Evaluation): an automated model-based approach for NOE assignment. J Biomol NMR. 2001 Apr; 19(4):321-9. Duggan BM, Legge GB, Dyson HJ, Wright PE. PMID: 11370778.
      View in: PubMed   Mentions: 40     Fields:    Translation:Cells
    42. Inherent flexibility in a potent inhibitor of blood coagulation, recombinant nematode anticoagulant protein c2. Eur J Biochem. 1999 Oct; 265(2):539-48. Duggan BM, Dyson HJ, Wright PE. PMID: 10504384.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    43. Conformational dynamics of thyroid hormones by variable temperature nuclear magnetic resonance: the role of side chain rotations and cisoid/transoid interconversions. J Med Chem. 1997 Jul 04; 40(14):2259-65. Duggan BM, Craik DJ. PMID: 9216845.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    44. Contribution of increased length and intact capping sequences to the conformational preference for helix in a 31-residue peptide from the C terminus of myohemerythrin. Biochemistry. 1997 Apr 29; 36(17):5234-44. Reymond MT, Huo S, Duggan B, Wright PE, Dyson HJ. PMID: 9136885.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    45. 1H and 13C NMR relaxation studies of molecular dynamics of the thyroid hormones thyroxine, 3,5,3'-triiodothyronine, and 3,5-diiodothyronine. J Med Chem. 1996 Sep 27; 39(20):4007-16. Duggan BM, Craik DJ. PMID: 8831766.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    46. Synthesis and structural characterisation of analogues of the potassium channel blocker charybdotoxin. Biochim Biophys Acta. 1996 Jan 04; 1292(1):31-8. Dyke TR, Duggan BM, Pennington MW, Byrnes ME, Kem WR, Norton RS. PMID: 8547346.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    47. Three-dimensional structure in solution of the calcium channel blocker omega-conotoxin. J Mol Biol. 1993 Nov 20; 234(2):405-20. Pallaghy PK, Duggan BM, Pennington MW, Norton RS. PMID: 8230223.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    Brendan's Networks
    Concepts (233)
    Derived automatically from this person's publications.
    _
    Co-Authors (35)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _