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    Jack Dixon

    TitleProfessor
    SchoolUniversity of California, San Diego
    DepartmentCellular and Molecular Medicine
    Address9500 Gilman Drive #0721
    CA La Jolla 92093
    Phone858-822-0491
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      Collapse Research 
      Collapse Research Activities and Funding
      Lafora epilepsy mechanisms: insights into brain metabolism
      NIH/NINDS R13NS096928May 1, 2016 - Apr 30, 2017
      Role: Principal Investigator
      YopT: A Yersinia Virulence Factor
      NIH/NIAID R21AI064614Apr 15, 2005 - Mar 31, 2007
      Role: Principal Investigator
      Fic-mediated Adenylylation
      NIH/NIGMS R01GM090328May 15, 2004 - Jul 31, 2014
      Role: Principal Investigator
      Molecular Mechanism of Pathogenesis
      NIH/NIAID R01AI060662May 15, 2004 - Apr 30, 2010
      Role: Principal Investigator
      Conference: Second Messengers &Protein Phosphorylation
      NIH/NIDDK R13DK060093Jun 1, 2001 - May 31, 2002
      Role: Principal Investigator
      FASEB SUMMER CONFERENCE--RECEPTORS/SIGNAL TRANSDUCTION
      NIH/NIDDK R13DK058154Jul 17, 2000 - Jun 30, 2001
      Role: Principal Investigator
      MODEL 370A-01 AUTOMATED DNA SEQUENCER SYSTEM
      NIH/NCRR S10RR004849Jul 20, 1989 - Jan 19, 1991
      Role: Principal Investigator
      IVEM and Image Analysis Resource
      NIH/NCRR P41RR004050Dec 12, 1988 - Mar 31, 2014
      Role: Co-Investigator
      EUCARYOTIC METABOLIC REGULATION
      NIH/NIDDK T32DK007532Dec 1, 1986 - Nov 30, 1997
      Role: Principal Investigator
      National Biomedical NMR Resource at Madison
      NIH P41RR002301Jul 1, 1985 - Feb 28, 2015
      Role: Co-Investigator
      Gastointestinal Hormone Research Core Center
      NIH P30DK034933Sep 30, 1984 - Nov 30, 2016
      Role: Co-Investigator
      ENDOCRINOLOGY STUDY SECTION
      NIH/CSR U09RG011666Jul 1, 1984 - Jun 30, 1991
      Role: Principal Investigator
      Novel Secreted Kinases
      NIH/NIDDK R01DK018024Jun 1, 1979 - Jul 31, 2019
      Role: Principal Investigator
      Phosphoinositide Phosphatases
      NIH/NIDDK R37DK018024Jun 1, 1979 - Jul 31, 2014
      Role: Principal Investigator
      STUDIES ON PANCREATIC HORMONES
      NIH/NIADDK R01AM018024Jun 1, 1979 - May 31, 1988
      Role: Principal Investigator
      General Clinical Research Center
      NIH M01RR000042Dec 1, 1977 - Feb 28, 2011
      Role: Co-Investigator
      Michigan Diabetes Research and Training Center
      NIH P60DK020572Sep 1, 1977 - Feb 9, 2013
      Role: Co-Investigator
      Novel Protein Phosphatases
      NIH/NIDDK R01DK018849May 1, 1976 - Jun 30, 2021
      Role: Principal Investigator
      REGULATION OF NEUROPEPTIDE BIOSYNTHESIS
      NIH/NIADDK R01AM018849May 1, 1976 - Jun 30, 1989
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon J, Kranias EG. Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proc Natl Acad Sci U S A. 2017 Aug 22; 114(34):9098-9103. PMID: 28784772.
        View in: PubMed
      2. Cui J, Zhu Q, Zhang H, Cianfrocco MA, Leschziner AE, Dixon J, Xiao J. Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding. Elife. 2017 Apr 22; 6. PMID: 28432788.
        View in: PubMed
      3. Nguyen KB, Sreelatha A, Durrant ES, Lopez-Garrido J, Muszewska A, Dudkiewicz M, Grynberg M, Yee S, Pogliano K, Tomchick DR, Pawlowski K, Dixon J, Tagliabracci VS. Phosphorylation of spore coat proteins by a family of atypical protein kinases. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):E3482-91. PMID: 27185916; PMCID: PMC4922149 [Available on 12/21/16].
      4. Guo X, Wang X, Wang Z, Banerjee S, Yang J, Huang L, Dixon J. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol. 2016 Feb; 18(2):202-12. PMID: 26655835; PMCID: PMC4844191.
      5. Tagliabracci VS, Wiley SE, Guo X, Kinch LN, Durrant E, Wen J, Xiao J, Cui J, Nguyen KB, Engel JL, Coon JJ, Grishin N, Pinna LA, Pagliarini DJ, Dixon J. A Single Kinase Generates the Majority of the Secreted Phosphoproteome. Cell. 2015 Jun 18; 161(7):1619-32. PMID: 26091039; PMCID: PMC4963185.
      6. Cui J, Xiao J, Tagliabracci VS, Wen J, Rahdar M, Dixon J. A secretory kinase complex regulates extracellular protein phosphorylation. Elife. 2015 Mar 19; 4:e06120. PMID: 25789606; PMCID: PMC4421793.
      7. Worby CA, Dixon J. Unpacking the unfolded protein response. Cell. 2014 Sep 11; 158(6):1221-1224. PMID: 25215479.
        View in: PubMed
      8. Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE, Xiao J, Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon J, Yeo CY, Whitman M. A secreted tyrosine kinase acts in the extracellular environment. Cell. 2014 Aug 28; 158(5):1033-1044. PMID: 25171405; PMCID: PMC4149754.
      9. Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon J. Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5520-5. PMID: 24706917; PMCID: PMC3992636.
      10. Bahmanyar S, Biggs R, Schuh AL, Desai A, Müller-Reichert T, Audhya A, Dixon J, Oegema K. Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev. 2014 Jan 15; 28(2):121-6. PMID: 24449268; PMCID: PMC3909786.
      11. Worby CA, Dixon J. PTEN. Annu Rev Biochem. 2014; 83:641-69. PMID: 24905788.
        View in: PubMed
      12. Wang Z, Hou Y, Guo X, van der Voet M, Boxem M, Dixon J, Chisholm AD, Jin Y. The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons. Neuron. 2013 Sep 04; 79(5):903-16. PMID: 24012004; PMCID: PMC3779136.
      13. Tagliabracci VS, Xiao J, Dixon J. Phosphorylation of substrates destined for secretion by the Fam20 kinases. Biochem Soc Trans. 2013 Aug; 41(4):1061-5. PMID: 23863179.
        View in: PubMed
      14. Xiao J, Tagliabracci VS, Wen J, Kim SA, Dixon J. Crystal structure of the Golgi casein kinase. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):10574-9. PMID: 23754375; PMCID: PMC3696822.
      15. Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon J, Murphy AN. Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med. 2013 Jun; 5(6):904-18. PMID: 23703906; PMCID: PMC3779451.
      16. Teh PG, Chen MJ, Engel JL, Worby CA, Manning G, Dixon J, Zhang J. Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica. J Biol Chem. 2013 Feb 15; 288(7):5176-85. PMID: 23293031; PMCID: PMC3576122.
      17. Tagliabracci VS, Pinna LA, Dixon J. Secreted protein kinases. Trends Biochem Sci. 2013 Mar; 38(3):121-30. PMID: 23276407; PMCID: PMC3582740.
      18. Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon J. Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science. 2012 Jun 01; 336(6085):1150-3. PMID: 22582013; PMCID: PMC3754843.
      19. Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon J, Dorrestein PC, Nizet V. Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98. PMID: 22371493; PMCID: PMC3340166.
      20. Guo X, Engel JL, Xiao J, Tagliabracci VS, Wang X, Huang L, Dixon J. UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18649-54. PMID: 21949367; PMCID: PMC3219150.
      21. Mattoo S, Durrant E, Chen MJ, Xiao J, Lazar CS, Manning G, Dixon J, Worby CA. Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem. 2011 Sep 16; 286(37):32834-42. PMID: 21795713; PMCID: PMC3173180.
      22. Xiao J, Engel JL, Zhang J, Chen MJ, Manning G, Dixon J. Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11860-5. PMID: 21730175; PMCID: PMC3142007.
      23. Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon J. Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 08; 13(6):690-700. PMID: 21641550; PMCID: PMC3119201.
      24. Worby CA, Dixon J. Glycogen synthase: an old enzyme with a new trick. Cell Metab. 2011 Mar 02; 13(3):233-4. PMID: 21356510.
        View in: PubMed
      25. Xiao J, Worby CA, Mattoo S, Sankaran B, Dixon J. Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol. 2010 Aug; 17(8):1004-10. PMID: 20622875; PMCID: PMC2920259.
      26. Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon J, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8. PMID: 20581111; PMCID: PMC2934687.
      27. Gentry MS, Dixon J, Worby CA. Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci. 2009 Dec; 34(12):628-39. PMID: 19818631; PMCID: PMC2805077.
      28. Worby CA, Mattoo S, Kruger RP, Corbeil LB, Koller A, Mendez JC, Zekarias B, Lazar C, Dixon J. The fic domain: regulation of cell signaling by adenylylation. Mol Cell. 2009 Apr 10; 34(1):93-103. PMID: 19362538; PMCID: PMC2820730.
      29. Dowen RH, Engel JL, Shao F, Ecker JR, Dixon J. A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem. 2009 Jun 05; 284(23):15867-79. PMID: 19346252; PMCID: PMC2708883.
      30. Rardin MJ, Wiley SE, Naviaux RK, Murphy AN, Dixon J. Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem. 2009 Jun 15; 389(2):157-64. PMID: 19341700; PMCID: PMC2713743.
      31. Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon J. Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem. 2009 May 08; 284(19):13004-12. PMID: 19286651; PMCID: PMC2676033.
      32. Wiley SE, Rardin MJ, Dixon J. Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET. Methods Enzymol. 2009; 456:233-46. PMID: 19348892.
        View in: PubMed
      33. Rardin MJ, Taylor GS, Dixon J. Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21. Methods Enzymol. 2009; 457:275-87. PMID: 19426873.
        View in: PubMed
      34. Iwasaki H, Murata Y, Kim Y, Hossain MI, Worby CA, Dixon J, McCormack T, Sasaki T, Okamura Y. A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):7970-5. PMID: 18524949; PMCID: PMC2430346.
      35. Rardin MJ, Wiley SE, Murphy AN, Pagliarini DJ, Dixon J. Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem. 2008 May 30; 283(22):15440-50. PMID: 18385140; PMCID: PMC2397459.
      36. Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon J. Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5879-84. PMID: 18375757; PMCID: PMC2311365.
      37. Robinson FL, Niesman IR, Beiswenger KK, Dixon J. Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4916-21. PMID: 18349142; PMCID: PMC2290800.
      38. Mattoo S, Alto NM, Dixon J. Subversion of myosin function by E. coli. Dev Cell. 2008 Jan; 14(1):8-10. PMID: 18194648.
        View in: PubMed
      39. Worby CA, Gentry MS, Dixon J. Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem. 2008 Feb 15; 283(7):4069-76. PMID: 18070875; PMCID: PMC2251628.
      40. Cheng A, Zhang M, Gentry MS, Worby CA, Dixon J, Saltiel AR. A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev. 2007 Oct 01; 21(19):2399-409. PMID: 17908927; PMCID: PMC1993871.
      41. Alto NM, Weflen AW, Rardin MJ, Yarar D, Lazar CS, Tonikian R, Koller A, Taylor SS, Boone C, Sidhu SS, Schmid SL, Hecht GA, Dixon J. The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J Cell Biol. 2007 Sep 24; 178(7):1265-78. PMID: 17893247; PMCID: PMC2064658.
      42. Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy AN, Nechushtai R, Dixon J, Jennings PA. MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14342-7. PMID: 17766440; PMCID: PMC1963346.
      43. Mattoo S, Lee YM, Dixon J. Interactions of bacterial effector proteins with host proteins. Curr Opin Immunol. 2007 Aug; 19(4):392-401. PMID: 17662586.
        View in: PubMed
      44. Gentry MS, Dowen RH, Worby CA, Mattoo S, Ecker JR, Dixon J. The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol. 2007 Jul 30; 178(3):477-88. PMID: 17646401; PMCID: PMC2064834.
      45. Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy AN, Jennings PA, Dixon J. The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem. 2007 Aug 17; 282(33):23745-9. PMID: 17584744.
        View in: PubMed
      46. Navarro L, Koller A, Nordfelth R, Wolf-Watz H, Taylor S, Dixon J. Identification of a molecular target for the Yersinia protein kinase A. Mol Cell. 2007 May 25; 26(4):465-77. PMID: 17531806.
        View in: PubMed
      47. Kim Y, Gentry MS, Harris TE, Wiley SE, Lawrence JC, Dixon J. A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6596-601. PMID: 17420445; PMCID: PMC1871831.
      48. Wiley SE, Murphy AN, Ross SA, van der Geer P, Dixon J. MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5318-23. PMID: 17376863; PMCID: PMC1838440.
      49. Worby CA, Gentry MS, Dixon J. Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J Biol Chem. 2006 Oct 13; 281(41):30412-8. PMID: 16901901; PMCID: PMC2774450.
      50. Robinson FL, Dixon J. Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol. 2006 Aug; 16(8):403-12. PMID: 16828287.
        View in: PubMed
      51. Worby CA, Dixon J. Microbiology. Bacteria seize control by acetylating host proteins. Science. 2006 May 26; 312(5777):1150-1. PMID: 16731519.
        View in: PubMed
      52. Alto NM, Shao F, Lazar CS, Brost RL, Chua G, Mattoo S, McMahon SA, Ghosh P, Hughes TR, Boone C, Dixon J. Identification of a bacterial type III effector family with G protein mimicry functions. Cell. 2006 Jan 13; 124(1):133-45. PMID: 16413487.
        View in: PubMed
      53. Begley MJ, Taylor GS, Brock MA, Ghosh P, Woods VL, Dixon J. Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase. Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4):927-32. PMID: 16410353; PMCID: PMC1347996.
      54. Pagliarini DJ, Dixon J. Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem Sci. 2006 Jan; 31(1):26-34. PMID: 16337125.
        View in: PubMed
      55. Begley MJ, Dixon J. The structure and regulation of myotubularin phosphatases. Curr Opin Struct Biol. 2005 Dec; 15(6):614-20. PMID: 16289848.
        View in: PubMed
      56. Worby CA, Dixon J. Phosphoinositide phosphatases: emerging roles as voltage sensors? Mol Interv. 2005 Oct; 5(5):274-7. PMID: 16249522.
        View in: PubMed
      57. Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon J. Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Mol Cell. 2005 Jul 22; 19(2):197-207. PMID: 16039589.
        View in: PubMed
      58. Robinson FL, Dixon J. The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J Biol Chem. 2005 Sep 09; 280(36):31699-707. PMID: 15998640.
        View in: PubMed
      59. Gentry MS, Worby CA, Dixon J. Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24):8501-6. PMID: 15930137; PMCID: PMC1150849.
      60. Navarro L, Alto NM, Dixon J. Functions of the Yersinia effector proteins in inhibiting host immune responses. Curr Opin Microbiol. 2005 Feb; 8(1):21-7. PMID: 15694853.
        View in: PubMed
      61. Pagliarini DJ, Worby CA, Dixon J. A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem. 2004 Sep 10; 279(37):38590-6. PMID: 15247229.
        View in: PubMed
      62. Worby CA, Dixon J. RNA interference in cultured Drosophila cells. Curr Protoc Mol Biol. 2004 Feb; Chapter 26:Unit 26.5. PMID: 18265350.
        View in: PubMed
      63. Taylor GS, Dixon J. Assaying phosphoinositide phosphatases. Methods Mol Biol. 2004; 284:217-27. PMID: 15173619.
        View in: PubMed
      64. Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon J, Firtel RA. A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem. 2003 Oct 10; 278(41):39866-73. PMID: 12878591.
        View in: PubMed
      65. Das S, Dixon J, Cho W. Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7491-6. PMID: 12808147; PMCID: PMC164614.
      66. Taylor GS, Dixon J. PTEN and myotubularins: families of phosphoinositide phosphatases. Methods Enzymol. 2003; 366:43-56. PMID: 14674238.
        View in: PubMed
      67. Worby CA, Dixon J. Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol. 2002 Dec; 3(12):919-31. PMID: 12461558.
        View in: PubMed
      68. Muda M, Worby CA, Simonson-Leff N, Clemens JC, Dixon J. Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem J. 2002 Aug 15; 366(Pt 1):73-7. PMID: 12014990; PMCID: PMC1222762.
      69. Worby CA, Simonson-Leff N, Clemens JC, Huddler D, Muda M, Dixon J. Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem. 2002 Mar 15; 277(11):9422-8. PMID: 11773052.
        View in: PubMed
      70. Mayo LD, Dixon J, Durden DL, Tonks NK, Donner DB. PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem. 2002 Feb 15; 277(7):5484-9. PMID: 11729185.
        View in: PubMed