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Emerging mechanisms of regulation for endoplasmic/sarcoplasmic reticulum Ca2+ stores by secretory pathway kinase FAM20C. Curr Opin Chem Biol. 2023 06; 74:102279.
Mayfield JE, Dixon JE. PMID: 36966700.
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PubMed Mentions:
1 Fields:
Translation:
Cells
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Hippo pathway regulation by phosphatidylinositol transfer protein and phosphoinositides. Nat Chem Biol. 2022 10; 18(10):1076-1086.
Li FL, Fu V, Liu G, Tang T, Konradi AW, Peng X, Kemper E, Cravatt BF, Franklin JM, Wu Z, Mayfield J, Dixon JE, Gerwick WH, Guan KL. PMID: 35788180.
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PubMed Mentions:
16 Fields:
Translation:
HumansCells
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The ABCs of the atypical Fam20 secretory pathway kinases. J Biol Chem. 2021 Jan-Jun; 296:100267.
Worby CA, Mayfield JE, Pollak AJ, Dixon JE, Banerjee S. PMID: 33759783; PMCID: PMC7948968.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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The stress-responsive kinase DYRK2 activates heat shock factor 1 promoting resistance to proteotoxic stress. Cell Death Differ. 2021 05; 28(5):1563-1578.
Moreno R, Banerjee S, Jackson AW, Quinn J, Baillie G, Dixon JE, Dinkova-Kostova AT, Edwards J, de la Vega L. PMID: 33268814; PMCID: PMC8166837.
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PubMed Mentions:
16 Fields:
Translation:
Humans
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POMK regulates dystroglycan function via LARGE1-mediated elongation of matriglycan. Elife. 2020 09 25; 9.
Walimbe AS, Okuma H, Joseph S, Yang T, Yonekawa T, Hord JM, Venzke D, Anderson ME, Torelli S, Manzur A, Devereaux M, Cuellar M, Prouty S, Ocampo Landa S, Yu L, Xiao J, Dixon JE, Muntoni F, Campbell KP. PMID: 32975514; PMCID: PMC7556876.
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PubMed Mentions:
16 Fields:
Translation:
AnimalsCells
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Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):328-336.
Liu X, Xiao W, Zhang Y, Wiley SE, Zuo T, Zheng Y, Chen N, Chen L, Wang X, Zheng Y, Huang L, Lin S, Murphy AN, Dixon JE, Xu P, Guo X. PMID: 31843888; PMCID: PMC6955308.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24881-24891.
Banerjee S, Wei T, Wang J, Lee JJ, Gutierrez HL, Chapman O, Wiley SE, Mayfield JE, Tandon V, Juarez EF, Chavez L, Liang R, Sah RL, Costello C, Mesirov JP, de la Vega L, Cooper KL, Dixon JE, Xiao J, Lei X. PMID: 31754034; PMCID: PMC6900511.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Ancestral roles of the Fam20C family of secreted protein kinases revealed in C. elegans. J Cell Biol. 2019 11 04; 218(11):3795-3811.
Gerson-Gurwitz A, Worby CA, Lee KY, Khaliullin R, Bouffard J, Cheerambathur D, Oegema K, Cram EJ, Dixon JE, Desai A. PMID: 31541016; PMCID: PMC6829671.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Reversible phosphorylation: a birthday tribute to Herb Tabor. J Biol Chem. 2019 02 01; 294(5):1638-1642.
Worby CA, Dixon JE. PMID: 30710011; PMCID: PMC6364790.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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A secretory pathway kinase regulates sarcoplasmic reticulum Ca2+ homeostasis and protects against heart failure. Elife. 2018 12 06; 7.
Pollak AJ, Liu C, Gudlur A, Mayfield JE, Dalton ND, Gu Y, Chen J, Heller Brown J, Hogan PG, Wiley SE, Peterson KL, Dixon JE. PMID: 30520731; PMCID: PMC6298778.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Enzymatic Phosphorylation of Ser in a Type I Collagen Peptide. Biophys J. 2018 12 18; 115(12):2327-2335.
Qiu Y, Poppleton E, Mekkat A, Yu H, Banerjee S, Wiley SE, Dixon JE, Kaplan DL, Lin YS, Brodsky B. PMID: 30527445; PMCID: PMC6302033.
View in:
PubMed Mentions:
7 Fields:
Translation:
Cells
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Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2. Proc Natl Acad Sci U S A. 2018 08 07; 115(32):8155-8160.
Banerjee S, Ji C, Mayfield JE, Goel A, Xiao J, Dixon JE, Guo X. PMID: 29987021; PMCID: PMC6094102.
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PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
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Structure and evolution of the Fam20 kinases. Nat Commun. 2018 03 23; 9(1):1218.
Zhang H, Zhu Q, Cui J, Wang Y, Chen MJ, Guo X, Tagliabracci VS, Dixon JE, Xiao J. PMID: 29572475; PMCID: PMC5865150.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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Phosphorylation of serine96 of histidine-rich calcium-binding protein by the Fam20C kinase functions to prevent cardiac arrhythmia. Proc Natl Acad Sci U S A. 2017 08 22; 114(34):9098-9103.
Pollak AJ, Haghighi K, Kunduri S, Arvanitis DA, Bidwell PA, Liu GS, Singh VP, Gonzalez DJ, Sanoudou D, Wiley SE, Dixon JE, Kranias EG. PMID: 28784772; PMCID: PMC5576816.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding. Elife. 2017 04 22; 6.
Cui J, Zhu Q, Zhang H, Cianfrocco MA, Leschziner AE, Dixon JE, Xiao J. PMID: 28432788; PMCID: PMC5413348.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Genomics and evolution of protein phosphatases. Sci Signal. 2017 Apr 11; 10(474).
Chen MJ, Dixon JE, Manning G. PMID: 28400531.
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PubMed Mentions:
124 Fields:
Translation:
HumansAnimalsCells
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Molecular Details Underlying Dynamic Structures and Regulation of the Human 26S Proteasome. Mol Cell Proteomics. 2017 05; 16(5):840-854.
Wang X, Cimermancic P, Yu C, Schweitzer A, Chopra N, Engel JL, Greenberg C, Huszagh AS, Beck F, Sakata E, Yang Y, Novitsky EJ, Leitner A, Nanni P, Kahraman A, Guo X, Dixon JE, Rychnovsky SD, Aebersold R, Baumeister W, Sali A, Huang L. PMID: 28292943; PMCID: PMC5417825.
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PubMed Mentions:
52 Fields:
Translation:
HumansCells
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Structure of protein O-mannose kinase reveals a unique active site architecture. Elife. 2016 11 23; 5.
Zhu Q, Venzke D, Walimbe AS, Anderson ME, Fu Q, Kinch LN, Wang W, Chen X, Grishin NV, Huang N, Yu L, Dixon JE, Campbell KP, Xiao J. PMID: 27879205; PMCID: PMC5142810.
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PubMed Mentions:
17 Fields:
Translation:
HumansAnimalsCells
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Phosphorylation of spore coat proteins by a family of atypical protein kinases. Proc Natl Acad Sci U S A. 2016 06 21; 113(25):E3482-91.
Nguyen KB, Sreelatha A, Durrant ES, Lopez-Garrido J, Muszewska A, Dudkiewicz M, Grynberg M, Yee S, Pogliano K, Tomchick DR, Pawlowski K, Dixon JE, Tagliabracci VS. PMID: 27185916; PMCID: PMC4922149.
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PubMed Mentions:
34 Fields:
Translation:
Cells
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Chirality of nanophotonic waveguide with embedded quantum emitter for unidirectional spin transfer. Nat Commun. 2016 Mar 31; 7:11183.
Coles RJ, Price DM, Dixon JE, Royall B, Clarke E, Kok P, Skolnick MS, Fox AM, Makhonin MN. PMID: 27029961; PMCID: PMC4821884.
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PubMed Mentions:
13 Fields:
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The 26S proteasome: A cell cycle regulator regulated by cell cycle. Cell Cycle. 2016; 15(7):875-6.
Guo X, Dixon JE. PMID: 26940127; PMCID: PMC4889267.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol. 2016 Feb; 18(2):202-12.
Guo X, Wang X, Wang Z, Banerjee S, Yang J, Huang L, Dixon JE. PMID: 26655835; PMCID: PMC4844191.
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PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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A Single Kinase Generates the Majority of the Secreted Phosphoproteome. Cell. 2015 Jun 18; 161(7):1619-32.
Tagliabracci VS, Wiley SE, Guo X, Kinch LN, Durrant E, Wen J, Xiao J, Cui J, Nguyen KB, Engel JL, Coon JJ, Grishin N, Pinna LA, Pagliarini DJ, Dixon JE. PMID: 26091039; PMCID: PMC4963185.
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PubMed Mentions:
172 Fields:
Translation:
HumansCells
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A new role for sphingosine: Up-regulation of Fam20C, the genuine casein kinase that phosphorylates secreted proteins. Biochim Biophys Acta. 2015 Oct; 1854(10 Pt B):1718-26.
Cozza G, Salvi M, Banerjee S, Tibaldi E, Tagliabracci VS, Dixon JE, Pinna LA. PMID: 25936777.
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PubMed Mentions:
9 Fields:
Translation:
HumansCells
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A potent and selective inhibitor for the UBLCP1 proteasome phosphatase. Bioorg Med Chem. 2015 Jun 15; 23(12):2798-809.
He Y, Guo X, Yu ZH, Wu L, Gunawan AM, Zhang Y, Dixon JE, Zhang ZY. PMID: 25907364; PMCID: PMC4451428.
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PubMed Mentions:
6 Fields:
Translation:
HumansCells
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A secretory kinase complex regulates extracellular protein phosphorylation. Elife. 2015 Mar 19; 4:e06120.
Cui J, Xiao J, Tagliabracci VS, Wen J, Rahdar M, Dixon JE. PMID: 25789606; PMCID: PMC4421793.
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PubMed Mentions:
72 Fields:
Translation:
HumansAnimalsCells
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Xylose phosphorylation functions as a molecular switch to regulate proteoglycan biosynthesis. Proc Natl Acad Sci U S A. 2014 Nov 04; 111(44):15723-8.
Wen J, Xiao J, Rahdar M, Choudhury BP, Cui J, Taylor GS, Esko JD, Dixon JE. PMID: 25331875; PMCID: PMC4226115.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Unpacking the unfolded protein response. Cell. 2014 Sep 11; 158(6):1221-1224.
Worby CA, Dixon JE. PMID: 25215479.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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A secreted tyrosine kinase acts in the extracellular environment. Cell. 2014 Aug 28; 158(5):1033-1044.
Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE, Xiao J, Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon JE, Yeo CY, Whitman M. PMID: 25171405; PMCID: PMC4149754.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Dynamic regulation of FGF23 by Fam20C phosphorylation, GalNAc-T3 glycosylation, and furin proteolysis. Proc Natl Acad Sci U S A. 2014 Apr 15; 111(15):5520-5.
Tagliabracci VS, Engel JL, Wiley SE, Xiao J, Gonzalez DJ, Nidumanda Appaiah H, Koller A, Nizet V, White KE, Dixon JE. PMID: 24706917; PMCID: PMC3992636.
View in:
PubMed Mentions:
160 Fields:
Translation:
HumansCells
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Phenol soluble modulin (PSM) variants of community-associated methicillin-resistant Staphylococcus aureus (MRSA) captured using mass spectrometry-based molecular networking. Mol Cell Proteomics. 2014 May; 13(5):1262-72.
Gonzalez DJ, Vuong L, Gonzalez IS, Keller N, McGrosso D, Hwang JH, Hung J, Zinkernagel A, Dixon JE, Dorrestein PC, Nizet V. PMID: 24567418; PMCID: PMC4014283.
View in:
PubMed Mentions:
10 Fields:
Translation:
HumansCells
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ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia. Cell Rep. 2014 Feb 13; 6(3):528-40.
Weisberg SP, Smith-Raska MR, Esquilin JM, Zhang J, Arenzana TL, Lau CM, Churchill M, Pan H, Klinakis A, Dixon JE, Mirny LA, Mukherjee S, Reizis B. PMID: 24485662; PMCID: PMC3936793.
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PubMed Mentions:
20 Fields:
Translation:
AnimalsCells
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Spatial control of phospholipid flux restricts endoplasmic reticulum sheet formation to allow nuclear envelope breakdown. Genes Dev. 2014 Jan 15; 28(2):121-6.
Bahmanyar S, Biggs R, Schuh AL, Desai A, Müller-Reichert T, Audhya A, Dixon JE, Oegema K. PMID: 24449268; PMCID: PMC3909786.
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PubMed Mentions:
47 Fields:
Translation:
AnimalsCells
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PTEN. Annu Rev Biochem. 2014; 83:641-69.
Worby CA, Dixon JE. PMID: 24905788.
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PubMed Mentions:
272 Fields:
Translation:
HumansAnimalsCells
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Recognition of the protein kinase AVRPPHB SUSCEPTIBLE1 by the disease resistance protein RESISTANCE TO PSEUDOMONAS SYRINGAE5 is dependent on s-acylation and an exposed loop in AVRPPHB SUSCEPTIBLE1. Plant Physiol. 2014 Jan; 164(1):340-51.
Qi D, Dubiella U, Kim SH, Sloss DI, Dowen RH, Dixon JE, Innes RW. PMID: 24225654; PMCID: PMC3875812.
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PubMed Mentions:
34 Fields:
Translation:
AnimalsCells
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The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons. Neuron. 2013 Sep 04; 79(5):903-16.
Wang Z, Hou Y, Guo X, van der Voet M, Boxem M, Dixon JE, Chisholm AD, Jin Y. PMID: 24012004; PMCID: PMC3779136.
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PubMed Mentions:
32 Fields:
Translation:
AnimalsCells
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Response to Wang et al.: Secreted protein kinases? Trends Biochem Sci. 2013 Sep; 38(9):425.
Tagliabracci VS, Pinna LA, Dixon JE. PMID: 23992948.
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PubMed Mentions:
3 Fields:
Translation:
HumansAnimals
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Phosphorylation of substrates destined for secretion by the Fam20 kinases. Biochem Soc Trans. 2013 Aug; 41(4):1061-5.
Tagliabracci VS, Xiao J, Dixon JE. PMID: 23863179.
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PubMed Mentions:
14 Fields:
Translation:
HumansCells
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Crystal structure of the Golgi casein kinase. Proc Natl Acad Sci U S A. 2013 Jun 25; 110(26):10574-9.
Xiao J, Tagliabracci VS, Wen J, Kim SA, Dixon JE. PMID: 23754375; PMCID: PMC3696822.
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PubMed Mentions:
40 Fields:
Translation:
HumansAnimalsCells
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Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. EMBO Mol Med. 2013 Jun; 5(6):904-18.
Wiley SE, Andreyev AY, Divakaruni AS, Karisch R, Perkins G, Wall EA, van der Geer P, Chen YF, Tsai TF, Simon MI, Neel BG, Dixon JE, Murphy AN. PMID: 23703906; PMCID: PMC3779451.
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PubMed Mentions:
62 Fields:
Translation:
AnimalsCells
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Identification of a mammalian-type phosphatidylglycerophosphate phosphatase in the Eubacterium Rhodopirellula baltica. J Biol Chem. 2013 Feb 15; 288(7):5176-85.
Teh PG, Chen MJ, Engel JL, Worby CA, Manning G, Dixon JE, Zhang J. PMID: 23293031; PMCID: PMC3576122.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Secreted protein kinases. Trends Biochem Sci. 2013 Mar; 38(3):121-30.
Tagliabracci VS, Pinna LA, Dixon JE. PMID: 23276407; PMCID: PMC3582740.
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PubMed Mentions:
75 Fields:
Translation:
HumansAnimals
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Widespread dynamic DNA methylation in response to biotic stress. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):E2183-91.
Dowen RH, Pelizzola M, Schmitz RJ, Lister R, Dowen JM, Nery JR, Dixon JE, Ecker JR. PMID: 22733782; PMCID: PMC3420206.
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PubMed Mentions:
423 Fields:
Translation:
AnimalsCells
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Secreted kinase phosphorylates extracellular proteins that regulate biomineralization. Science. 2012 Jun 01; 336(6085):1150-3.
Tagliabracci VS, Engel JL, Wen J, Wiley SE, Worby CA, Kinch LN, Xiao J, Grishin NV, Dixon JE. PMID: 22582013; PMCID: PMC3754843.
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PubMed Mentions:
227 Fields:
Translation:
HumansAnimalsCells
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Novel phenol-soluble modulin derivatives in community-associated methicillin-resistant Staphylococcus aureus identified through imaging mass spectrometry. J Biol Chem. 2012 Apr 20; 287(17):13889-98.
Gonzalez DJ, Okumura CY, Hollands A, Kersten R, Akong-Moore K, Pence MA, Malone CL, Derieux J, Moore BS, Horswill AR, Dixon JE, Dorrestein PC, Nizet V. PMID: 22371493; PMCID: PMC3340166.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Nuclear envelope phosphatase 1-regulatory subunit 1 (formerly TMEM188) is the metazoan Spo7p ortholog and functions in the lipin activation pathway. J Biol Chem. 2012 Jan 27; 287(5):3123-37.
Han S, Bahmanyar S, Zhang P, Grishin N, Oegema K, Crooke R, Graham M, Reue K, Dixon JE, Goodman JM. PMID: 22134922; PMCID: PMC3283218.
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PubMed Mentions:
61 Fields:
Translation:
HumansAnimalsCells
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UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity. Proc Natl Acad Sci U S A. 2011 Nov 15; 108(46):18649-54.
Guo X, Engel JL, Xiao J, Tagliabracci VS, Wang X, Huang L, Dixon JE. PMID: 21949367; PMCID: PMC3219150.
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PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Comparative analysis of Histophilus somni immunoglobulin-binding protein A (IbpA) with other fic domain-containing enzymes reveals differences in substrate and nucleotide specificities. J Biol Chem. 2011 Sep 16; 286(37):32834-42.
Mattoo S, Durrant E, Chen MJ, Xiao J, Lazar CS, Manning G, Dixon JE, Worby CA. PMID: 21795713; PMCID: PMC3173180.
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PubMed Mentions:
37 Fields:
Translation:
HumansCells
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Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis. Proc Natl Acad Sci U S A. 2011 Jul 19; 108(29):11860-5.
Xiao J, Engel JL, Zhang J, Chen MJ, Manning G, Dixon JE. PMID: 21730175; PMCID: PMC3142007.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis. Cell Metab. 2011 Jun 08; 13(6):690-700.
Zhang J, Guan Z, Murphy AN, Wiley SE, Perkins GA, Worby CA, Engel JL, Heacock P, Nguyen OK, Wang JH, Raetz CR, Dowhan W, Dixon JE. PMID: 21641550; PMCID: PMC3119201.
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PubMed Mentions:
100 Fields:
Translation:
AnimalsCells
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Expansion of type II CAAX proteases reveals evolutionary origin of γ-secretase subunit APH-1. J Mol Biol. 2011 Jul 01; 410(1):18-26.
Pei J, Mitchell DA, Dixon JE, Grishin NV. PMID: 21570408; PMCID: PMC3155266.
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PubMed Mentions:
39 Fields:
Translation:
Cells
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Glycogen synthase: an old enzyme with a new trick. Cell Metab. 2011 Mar 02; 13(3):233-4.
Worby CA, Dixon JE. PMID: 21356510.
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PubMed Mentions: Fields:
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Voltage-sensing phosphatase: its molecular relationship with PTEN. Physiology (Bethesda). 2011 Feb; 26(1):6-13.
Okamura Y, Dixon JE. PMID: 21357898.
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PubMed Mentions:
38 Fields:
Translation:
HumansAnimalsCells
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Structural basis of Fic-mediated adenylylation. Nat Struct Mol Biol. 2010 Aug; 17(8):1004-10.
Xiao J, Worby CA, Mattoo S, Sankaran B, Dixon JE. PMID: 20622875; PMCID: PMC2920259.
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PubMed Mentions:
53 Fields:
Translation:
HumansCells
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Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. J Biol Chem. 2010 Sep 03; 285(36):28220-8.
Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. PMID: 20581111; PMCID: PMC2934687.
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PubMed Mentions:
43 Fields:
Translation:
HumansCells
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Climate change and the integrity of science. Science. 2010 May 07; 328(5979):689-90.
Gleick PH, Adams RM, Amasino RM, Anders E, Anderson DJ, Anderson WW, Anselin LE, Arroyo MK, Asfaw B, Ayala FJ, Bax A, Bebbington AJ, Bell G, Bennett MV, Bennetzen JL, Berenbaum MR, Berlin OB, Bjorkman PJ, Blackburn E, Blamont JE, Botchan MR, Boyer JS, Boyle EA, Branton D, Briggs SP, Briggs WR, Brill WJ, Britten RJ, Broecker WS, Brown JH, Brown PO, Brunger AT, Cairns J, Canfield DE, Carpenter SR, Carrington JC, Cashmore AR, Castilla JC, Cazenave A, Chapin FS, Ciechanover AJ, Clapham DE, Clark WC, Clayton RN, Coe MD, Conwell EM, Cowling EB, Cowling RM, Cox CS, Croteau RB, Crothers DM, Crutzen PJ, Daily GC, Dalrymple GB, Dangl JL, Darst SA, Davies DR, Davis MB, De Camilli PV, Dean C, DeFries RS, Deisenhofer J, Delmer DP, DeLong EF, DeRosier DJ, Diener TO, Dirzo R, Dixon JE, Donoghue MJ, Doolittle RF, Dunne T, Ehrlich PR, Eisenstadt SN, Eisner T, Emanuel KA, Englander SW, Ernst WG, Falkowski PG, Feher G, Ferejohn JA, Fersht A, Fischer EH, Fischer R, Flannery KV, Frank J, Frey PA, Fridovich I, Frieden C, Futuyma DJ, Gardner WR, Garrett CJ, Gilbert W, Goldberg RB, Goodenough WH, Goodman CS, Goodman M, Greengard P, Hake S, Hammel G, Hanson S, Harrison SC, Hart SR, Hartl DL, Haselkorn R, Hawkes K, Hayes JM, Hille B, Hökfelt T, House JS, Hout M, Hunten DM, Izquierdo IA, Jagendorf AT, Janzen DH, Jeanloz R, Jencks CS, Jury WA, Kaback HR, Kailath T, Kay P, Kay SA, Kennedy D, Kerr A, Kessler RC, Khush GS, Kieffer SW, Kirch PV, Kirk K, Kivelson MG, Klinman JP, Klug A, Knopoff L, Kornberg H, Kutzbach JE, Lagarias JC, Lambeck K, Landy A, Langmuir CH, Larkins BA, Le Pichon XT, Lenski RE, Leopold EB, Levin SA, Levitt M, Likens GE, Lippincott-Schwartz J, Lorand L, Lovejoy CO, Lynch M, Mabogunje AL, Malone TF, Manabe S, Marcus J, Massey DS, McWilliams JC, Medina E, Melosh HJ, Meltzer DJ, Michener CD, Miles EL, Mooney HA, Moore PB, Morel FM, Mosley-Thompson ES, Moss B, Munk WH, Myers N, Nair GB, Nathans J, Nester EW, Nicoll RA, Novick RP, O'Connell JF, Olsen PE, Opdyke ND, Oster GF, Ostrom E, Pace NR, Paine RT, Palmiter RD, Pedlosky J, Petsko GA, Pettengill GH, Philander SG, Piperno DR, Pollard TD, Price PB, Reichard PA, Reskin BF, Ricklefs RE, Rivest RL, Roberts JD, Romney AK, Rossmann MG, Russell DW, Rutter WJ, Sabloff JA, Sagdeev RZ, Sahlins MD, Salmond A, Sanes JR, Schekman R, Schellnhuber J, Schindler DW, Schmitt J, Schneider SH, Schramm VL, Sederoff RR, Shatz CJ, Sherman F, Sidman RL, Sieh K, Simons EL, Singer BH, Singer MF, Skyrms B, Sleep NH, Smith BD, Snyder SH, Sokal RR, Spencer CS, Steitz TA, Strier KB, Südhof TC, Taylor SS, Terborgh J, Thomas DH, Thompson LG, Tjian RT, Turner MG, Uyeda S, Valentine JW, Valentine JS, Van Etten JL, van Holde KE, Vaughan M, Verba S, von Hippel PH, Wake DB, Walker A, Walker JE, Watson EB, Watson PJ, Weigel D, Wessler SR, West-Eberhard MJ, White TD, Wilson WJ, Wolfenden RV, Wood JA, Woodwell GM, Wright HE, Wu C, Wunsch C, Zoback ML. PMID: 20448167; PMCID: PMC5125622.
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PubMed Mentions:
10 Fields:
Translation:
Humans
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Structural and functional analysis of the phosphoryl transfer reaction mediated by the human small C-terminal domain phosphatase, Scp1. Protein Sci. 2010 May; 19(5):974-86.
Zhang M, Liu J, Kim Y, Dixon JE, Pfaff SL, Gill GN, Noel JP, Zhang Y. PMID: 20222012; PMCID: PMC2868240.
View in:
PubMed Mentions:
24 Fields:
Translation:
HumansCells
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Pharmacological targeting of the mitochondrial phosphatase PTPMT1. J Pharmacol Exp Ther. 2010 May; 333(2):584-92.
Doughty-Shenton D, Joseph JD, Zhang J, Pagliarini DJ, Kim Y, Lu D, Dixon JE, Casey PJ. PMID: 20167843; PMCID: PMC2872949.
View in:
PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Lafora disease: insights into neurodegeneration from plant metabolism. Trends Biochem Sci. 2009 Dec; 34(12):628-39.
Gentry MS, Dixon JE, Worby CA. PMID: 19818631; PMCID: PMC2805077.
View in:
PubMed Mentions:
51 Fields:
Translation:
HumansAnimals
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The fic domain: regulation of cell signaling by adenylylation. Mol Cell. 2009 Apr 10; 34(1):93-103.
Worby CA, Mattoo S, Kruger RP, Corbeil LB, Koller A, Mendez JC, Zekarias B, Lazar C, Dixon JE. PMID: 19362538; PMCID: PMC2820730.
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PubMed Mentions:
134 Fields:
Translation:
HumansCells
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A family of bacterial cysteine protease type III effectors utilizes acylation-dependent and -independent strategies to localize to plasma membranes. J Biol Chem. 2009 Jun 05; 284(23):15867-79.
Dowen RH, Engel JL, Shao F, Ecker JR, Dixon JE. PMID: 19346252; PMCID: PMC2708883.
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PubMed Mentions:
47 Fields:
Translation:
Cells
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Monitoring phosphorylation of the pyruvate dehydrogenase complex. Anal Biochem. 2009 Jun 15; 389(2):157-64.
Rardin MJ, Wiley SE, Naviaux RK, Murphy AN, Dixon JE. PMID: 19341700; PMCID: PMC2713743.
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PubMed Mentions:
78 Fields:
Translation:
HumansAnimalsCells
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Structural and functional dissection of the heterocyclic peptide cytotoxin streptolysin S. J Biol Chem. 2009 May 08; 284(19):13004-12.
Mitchell DA, Lee SW, Pence MA, Markley AL, Limm JD, Nizet V, Dixon JE. PMID: 19286651; PMCID: PMC2676033.
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PubMed Mentions:
56 Fields:
Translation:
AnimalsCells
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Chapter 13 Localization and function of the 2Fe-2S outer mitochondrial membrane protein mitoNEET. Methods Enzymol. 2009; 456:233-46.
Wiley SE, Rardin MJ, Dixon JE. PMID: 19348892.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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Distinguishing mitochondrial inner membrane orientation of dual specific phosphatase 18 and 21. Methods Enzymol. 2009; 457:275-87.
Rardin MJ, Taylor GS, Dixon JE. PMID: 19426873.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Structure and function of Salmonella SifA indicate that its interactions with SKIP, SseJ, and RhoA family GTPases induce endosomal tubulation. Cell Host Microbe. 2008 Nov 13; 4(5):434-46.
Ohlson MB, Huang Z, Alto NM, Blanc MP, Dixon JE, Chai J, Miller SI. PMID: 18996344; PMCID: PMC2658612.
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PubMed Mentions:
86 Fields:
Translation:
HumansCells
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Protection of mice against H. somni septicemia by vaccination with recombinant immunoglobulin binding protein subunits. Vaccine. 2008 Aug 18; 26(35):4506-12.
Geertsema RS, Worby C, Kruger RP, Tagawa Y, Russo R, Herdman DS, Lo K, Kimball RA, Dixon J, Corbeil LB. PMID: 18590787; PMCID: PMC2659705.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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A voltage-sensing phosphatase, Ci-VSP, which shares sequence identity with PTEN, dephosphorylates phosphatidylinositol 4,5-bisphosphate. Proc Natl Acad Sci U S A. 2008 Jun 10; 105(23):7970-5.
Iwasaki H, Murata Y, Kim Y, Hossain MI, Worby CA, Dixon JE, McCormack T, Sasaki T, Okamura Y. PMID: 18524949; PMCID: PMC2430346.
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PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
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Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane. J Biol Chem. 2008 May 30; 283(22):15440-50.
Rardin MJ, Wiley SE, Murphy AN, Pagliarini DJ, Dixon JE. PMID: 18385140; PMCID: PMC2397459.
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PubMed Mentions:
12 Fields:
Translation:
AnimalsCells
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Discovery of a widely distributed toxin biosynthetic gene cluster. Proc Natl Acad Sci U S A. 2008 Apr 15; 105(15):5879-84.
Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. PMID: 18375757; PMCID: PMC2311365.
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PubMed Mentions:
125 Fields:
Translation:
HumansCells
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Loss of the inactive myotubularin-related phosphatase Mtmr13 leads to a Charcot-Marie-Tooth 4B2-like peripheral neuropathy in mice. Proc Natl Acad Sci U S A. 2008 Mar 25; 105(12):4916-21.
Robinson FL, Niesman IR, Beiswenger KK, Dixon JE. PMID: 18349142; PMCID: PMC2290800.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Subversion of myosin function by E. coli. Dev Cell. 2008 Jan; 14(1):8-10.
Mattoo S, Alto NM, Dixon JE. PMID: 18194648.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins. Methods Enzymol. 2008; 439:131-43.
Alto NM, Dixon JE. PMID: 18374161.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Malin decreases glycogen accumulation by promoting the degradation of protein targeting to glycogen (PTG). J Biol Chem. 2008 Feb 15; 283(7):4069-76.
Worby CA, Gentry MS, Dixon JE. PMID: 18070875; PMCID: PMC2251628.
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PubMed Mentions:
84 Fields:
Translation:
HumansAnimalsCells
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A role for AGL ubiquitination in the glycogen storage disorders of Lafora and Cori's disease. Genes Dev. 2007 Oct 01; 21(19):2399-409.
Cheng A, Zhang M, Gentry MS, Worby CA, Dixon JE, Saltiel AR. PMID: 17908927; PMCID: PMC1993871.
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PubMed Mentions:
54 Fields:
Translation:
HumansAnimalsCells
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The type III effector EspF coordinates membrane trafficking by the spatiotemporal activation of two eukaryotic signaling pathways. J Cell Biol. 2007 Sep 24; 178(7):1265-78.
Alto NM, Weflen AW, Rardin MJ, Yarar D, Lazar CS, Tonikian R, Koller A, Taylor SS, Boone C, Sidhu SS, Schmid SL, Hecht GA, Dixon JE. PMID: 17893247; PMCID: PMC2064658.
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PubMed Mentions:
68 Fields:
Translation:
HumansAnimalsCells
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MitoNEET is a uniquely folded 2Fe 2S outer mitochondrial membrane protein stabilized by pioglitazone. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14342-7.
Paddock ML, Wiley SE, Axelrod HL, Cohen AE, Roy M, Abresch EC, Capraro D, Murphy AN, Nechushtai R, Dixon JE, Jennings PA. PMID: 17766440; PMCID: PMC1963346.
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PubMed Mentions:
141 Fields:
Translation:
HumansCells
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Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. Oncogene. 2008 Feb 14; 27(8):1079-86.
Faucherre A, Taylor GS, Overvoorde J, Dixon JE, Hertog Jd. PMID: 17704803.
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PubMed Mentions:
44 Fields:
Translation:
HumansAnimals
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Interactions of bacterial effector proteins with host proteins. Curr Opin Immunol. 2007 Aug; 19(4):392-401.
Mattoo S, Lee YM, Dixon JE. PMID: 17662586.
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PubMed Mentions:
33 Fields:
Translation:
HumansAnimalsCells
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The phosphatase laforin crosses evolutionary boundaries and links carbohydrate metabolism to neuronal disease. J Cell Biol. 2007 Jul 30; 178(3):477-88.
Gentry MS, Dowen RH, Worby CA, Mattoo S, Ecker JR, Dixon JE. PMID: 17646401; PMCID: PMC2064834.
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PubMed Mentions:
77 Fields:
Translation:
HumansAnimalsCells
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A reply from Howard Hughes Medical Institute (HHMI). J Cell Biol. 2007 Jul 30; 178(3):343; discussion 343.
Cech T, Dixon J, Meehan A, Briggs J, Rhodes C. PMID: 17646394; PMCID: PMC2064853.
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PubMed Mentions:
1 Fields:
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The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. J Biol Chem. 2007 Aug 17; 282(33):23745-9.
Wiley SE, Paddock ML, Abresch EC, Gross L, van der Geer P, Nechushtai R, Murphy AN, Jennings PA, Dixon JE. PMID: 17584744.
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PubMed Mentions:
84 Fields:
Translation:
HumansCells
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Identification of a molecular target for the Yersinia protein kinase A. Mol Cell. 2007 May 25; 26(4):465-77.
Navarro L, Koller A, Nordfelth R, Wolf-Watz H, Taylor S, Dixon JE. PMID: 17531806.
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PubMed Mentions:
53 Fields:
Translation:
HumansCells
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A conserved phosphatase cascade that regulates nuclear membrane biogenesis. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6596-601.
Kim Y, Gentry MS, Harris TE, Wiley SE, Lawrence JC, Dixon JE. PMID: 17420445; PMCID: PMC1871831.
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PubMed Mentions:
96 Fields:
Translation:
HumansAnimalsCells
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MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5318-23.
Wiley SE, Murphy AN, Ross SA, van der Geer P, Dixon JE. PMID: 17376863; PMCID: PMC1838440.
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PubMed Mentions:
140 Fields:
Translation:
HumansAnimalsCells
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The Sorcerer II Global Ocean Sampling expedition: expanding the universe of protein families. PLoS Biol. 2007 Mar; 5(3):e16.
Yooseph S, Sutton G, Rusch DB, Halpern AL, Williamson SJ, Remington K, Eisen JA, Heidelberg KB, Manning G, Li W, Jaroszewski L, Cieplak P, Miller CS, Li H, Mashiyama ST, Joachimiak MP, van Belle C, Chandonia JM, Soergel DA, Zhai Y, Natarajan K, Lee S, Raphael BJ, Bafna V, Friedman R, Brenner SE, Godzik A, Eisenberg D, Dixon JE, Taylor SS, Strausberg RL, Frazier M, Venter JC. PMID: 17355171; PMCID: PMC1821046.
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PubMed Mentions:
325 Fields:
Translation:
PHPublic Health
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Determinants for dephosphorylation of the RNA polymerase II C-terminal domain by Scp1. Mol Cell. 2006 Dec 08; 24(5):759-770.
Zhang Y, Kim Y, Genoud N, Gao J, Kelly JW, Pfaff SL, Gill GN, Dixon JE, Noel JP. PMID: 17157258; PMCID: PMC2859291.
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PubMed Mentions:
63 Fields:
Translation:
HumansCells
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Laforin, a dual specificity phosphatase that dephosphorylates complex carbohydrates. J Biol Chem. 2006 Oct 13; 281(41):30412-8.
Worby CA, Gentry MS, Dixon JE. PMID: 16901901; PMCID: PMC2774450.
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PubMed Mentions:
109 Fields:
Translation:
HumansAnimalsCells
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Myotubularin phosphatases: policing 3-phosphoinositides. Trends Cell Biol. 2006 Aug; 16(8):403-12.
Robinson FL, Dixon JE. PMID: 16828287.
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PubMed Mentions:
108 Fields:
Translation:
HumansAnimals
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The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers. Mol Cancer. 2006 Jun 19; 5:25.
Paulsen MT, Starks AM, Derheimer FA, Hanasoge S, Li L, Dixon JE, Ljungman M. PMID: 16784539; PMCID: PMC1524803.
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PubMed Mentions:
13 Fields:
Translation:
HumansCells
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Microbiology. Bacteria seize control by acetylating host proteins. Science. 2006 May 26; 312(5777):1150-1.
Worby CA, Dixon JE. PMID: 16731519.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Identification of a bacterial type III effector family with G protein mimicry functions. Cell. 2006 Jan 13; 124(1):133-45.
Alto NM, Shao F, Lazar CS, Brost RL, Chua G, Mattoo S, McMahon SA, Ghosh P, Hughes TR, Boone C, Dixon JE. PMID: 16413487.
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PubMed Mentions:
140 Fields:
Translation:
HumansAnimalsCells
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Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase. Proc Natl Acad Sci U S A. 2006 Jan 24; 103(4):927-32.
Begley MJ, Taylor GS, Brock MA, Ghosh P, Woods VL, Dixon JE. PMID: 16410353; PMCID: PMC1347996.
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PubMed Mentions:
44 Fields:
Translation:
HumansCells
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Identification of otubain 1 as a novel substrate for the Yersinia protein kinase using chemical genetics and mass spectrometry. FEBS Lett. 2006 Jan 09; 580(1):179-83.
Juris SJ, Shah K, Shokat K, Dixon JE, Vacratsis PO. PMID: 16364312.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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Mitochondrial modulation: reversible phosphorylation takes center stage? Trends Biochem Sci. 2006 Jan; 31(1):26-34.
Pagliarini DJ, Dixon JE. PMID: 16337125.
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PubMed Mentions:
97 Fields:
Translation:
HumansAnimalsCells
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The structure and regulation of myotubularin phosphatases. Curr Opin Struct Biol. 2005 Dec; 15(6):614-20.
Begley MJ, Dixon JE. PMID: 16289848.
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PubMed Mentions:
32 Fields:
Translation:
HumansCells
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Phosphoinositide phosphatases: emerging roles as voltage sensors? Mol Interv. 2005 Oct; 5(5):274-7.
Worby CA, Dixon JE. PMID: 16249522.
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PubMed Mentions:
10 Fields:
Translation:
HumansAnimals
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Involvement of a mitochondrial phosphatase in the regulation of ATP production and insulin secretion in pancreatic beta cells. Mol Cell. 2005 Jul 22; 19(2):197-207.
Pagliarini DJ, Wiley SE, Kimple ME, Dixon JR, Kelly P, Worby CA, Casey PJ, Dixon JE. PMID: 16039589.
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PubMed Mentions:
68 Fields:
Translation:
AnimalsCells
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The phosphoinositide-3-phosphatase MTMR2 associates with MTMR13, a membrane-associated pseudophosphatase also mutated in type 4B Charcot-Marie-Tooth disease. J Biol Chem. 2005 Sep 09; 280(36):31699-707.
Robinson FL, Dixon JE. PMID: 15998640.
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PubMed Mentions:
51 Fields:
Translation:
HumansCells
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Insights into Lafora disease: malin is an E3 ubiquitin ligase that ubiquitinates and promotes the degradation of laforin. Proc Natl Acad Sci U S A. 2005 Jun 14; 102(24):8501-6.
Gentry MS, Worby CA, Dixon JE. PMID: 15930137; PMCID: PMC1150849.
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PubMed Mentions:
112 Fields:
Translation:
HumansCells
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Functions of the Yersinia effector proteins in inhibiting host immune responses. Curr Opin Microbiol. 2005 Feb; 8(1):21-7.
Navarro L, Alto NM, Dixon JE. PMID: 15694853.
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PubMed Mentions:
53 Fields:
Translation:
HumansCells
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A PTEN-like phosphatase with a novel substrate specificity. J Biol Chem. 2004 Sep 10; 279(37):38590-6.
Pagliarini DJ, Worby CA, Dixon JE. PMID: 15247229.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatases in the human genome. Cell. 2004 Jun 11; 117(6):699-711.
Alonso A, Sasin J, Bottini N, Friedberg I, Friedberg I, Osterman A, Godzik A, Hunter T, Dixon J, Mustelin T. PMID: 15186772.
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PubMed Mentions:
701 Fields:
Translation:
HumansCells
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Suppression of a phosphatidylinositol 3-kinase signal by a specific spliced variant of Drosophila PTEN. FEBS Lett. 2004 May 07; 565(1-3):43-7.
Maehama T, Kosaka N, Okahara F, Takeuchi K, Umeda M, Dixon JE, Kanaho Y. PMID: 15135050.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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RNA interference in cultured Drosophila cells. Curr Protoc Mol Biol. 2004 Feb; Chapter 26:Unit 26.5.
Worby CA, Dixon JE. PMID: 18265350.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Assaying phosphoinositide phosphatases. Methods Mol Biol. 2004; 284:217-27.
Taylor GS, Dixon JE. PMID: 15173619.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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The crystal structure of Pseudomonas avirulence protein AvrPphB: a papain-like fold with a distinct substrate-binding site. Proc Natl Acad Sci U S A. 2004 Jan 06; 101(1):302-7.
Zhu M, Shao F, Innes RW, Dixon JE, Xu Z. PMID: 14694194; PMCID: PMC314180.
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PubMed Mentions:
53 Fields:
Translation:
Cells
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Crystal structure of a phosphoinositide phosphatase, MTMR2: insights into myotubular myopathy and Charcot-Marie-Tooth syndrome. Mol Cell. 2003 Dec; 12(6):1391-402.
Begley MJ, Taylor GS, Kim SA, Veine DM, Dixon JE, Stuckey JA. PMID: 14690594.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Cleavage of Arabidopsis PBS1 by a bacterial type III effector. Science. 2003 Aug 29; 301(5637):1230-3.
Shao F, Golstein C, Ade J, Stoutemyer M, Dixon JE, Innes RW. PMID: 12947197.
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PubMed Mentions:
199 Fields:
Translation:
HumansAnimalsCells
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A PTEN-related 5-phosphatidylinositol phosphatase localized in the Golgi. J Biol Chem. 2003 Oct 10; 278(41):39866-73.
Merlot S, Meili R, Pagliarini DJ, Maehama T, Dixon JE, Firtel RA. PMID: 12878591.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Membrane-binding and activation mechanism of PTEN. Proc Natl Acad Sci U S A. 2003 Jun 24; 100(13):7491-6.
Das S, Dixon JE, Cho W. PMID: 12808147; PMCID: PMC164614.
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PubMed Mentions:
159 Fields:
Translation:
HumansCells
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Regulation of myotubularin-related (MTMR)2 phosphatidylinositol phosphatase by MTMR5, a catalytically inactive phosphatase. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4492-7.
Kim SA, Vacratsis PO, Firestein R, Cleary ML, Dixon JE. PMID: 12668758; PMCID: PMC153583.
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PubMed Mentions:
58 Fields:
Translation:
HumansAnimalsCells
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The yersinia virulence factor YopM forms a novel protein complex with two cellular kinases. J Biol Chem. 2003 May 16; 278(20):18514-23.
McDonald C, Vacratsis PO, Bliska JB, Dixon JE. PMID: 12626518.
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PubMed Mentions:
64 Fields:
Translation:
HumansCells
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Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases. Proc Natl Acad Sci U S A. 2003 Feb 04; 100(3):904-9.
Shao F, Vacratsis PO, Bao Z, Bowers KE, Fierke CA, Dixon JE. PMID: 12538863; PMCID: PMC298699.
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PubMed Mentions:
58 Fields:
Translation:
HumansCells
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YopT is a cysteine protease cleaving Rho family GTPases. Adv Exp Med Biol. 2003; 529:79-84.
Shao F, Dixon JE. PMID: 12756732.
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PubMed Mentions:
13 Fields:
Translation:
Cells
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PTEN and myotubularins: families of phosphoinositide phosphatases. Methods Enzymol. 2003; 366:43-56.
Taylor GS, Dixon JE. PMID: 14674238.
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PubMed Mentions:
16 Fields:
Translation:
HumansAnimalsCells
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Overview of the Alliance for Cellular Signaling. Nature. 2002 Dec 12; 420(6916):703-6.
Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, Gold M, Weiss A, Stull JT, Berridge MJ, Cantley LC, Catterall WA, Coughlin SR, Olson EN, Smith TF, Brugge JS, Botstein D, Dixon JE, Hunter T, Lefkowitz RJ, Pawson AJ, Sternberg PW, Varmus H, Subramaniam S, Sinkovits RS, Li J, Mock D, Ning Y, Saunders B, Sternweis PC, Hilgemann D, Scheuermann RH, DeCamp D, Hsueh R, Lin KM, Ni Y, Seaman WE, Simpson PC, O'Connell TD, Roach T, Simon MI, Choi S, Eversole-Cire P, Fraser I, Mumby MC, Zhao Y, Brekken D, Shu H, Meyer T, Chandy G, Heo WD, Liou J, O'Rourke N, Verghese M, Mumby SM, Han H, Brown HA, Forrester JS, Ivanova P, Milne SB, Casey PJ, Harden TK, Arkin AP, Doyle J, Gray ML, Meyer T, Michnick S, Schmidt MA, Toner M, Tsien RY, Natarajan M, Ranganathan R, Sambrano GR, Participating investigators and scientists of the Alliance for Cellular Signaling. PMID: 12478301.
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37 Fields:
Translation:
HumansCells
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Sorting out the cellular functions of sorting nexins. Nat Rev Mol Cell Biol. 2002 Dec; 3(12):919-31.
Worby CA, Dixon JE. PMID: 12461558.
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PubMed Mentions:
184 Fields:
Translation:
HumansAnimalsCells
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PTEN and myotubularin phosphatases: from 3-phosphoinositide dephosphorylation to disease. Trends Cell Biol. 2002 Dec; 12(12):579-85.
Wishart MJ, Dixon JE. PMID: 12495846.
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PubMed Mentions:
56 Fields:
Translation:
HumansCells
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Use of double-stranded RNA-mediated interference to determine the substrates of protein tyrosine kinases and phosphatases. Biochem J. 2002 Aug 15; 366(Pt 1):73-7.
Muda M, Worby CA, Simonson-Leff N, Clemens JC, Dixon JE. PMID: 12014990; PMCID: PMC1222762.
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PubMed Mentions:
9 Fields:
Translation:
AnimalsCells
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A Yersinia effector and a Pseudomonas avirulence protein define a family of cysteine proteases functioning in bacterial pathogenesis. Cell. 2002 May 31; 109(5):575-88.
Shao F, Merritt PM, Bao Z, Innes RW, Dixon JE. PMID: 12062101.
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PubMed Mentions:
145 Fields:
Translation:
HumansAnimalsCells
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Role of Yersinia murine toxin in survival of Yersinia pestis in the midgut of the flea vector. Science. 2002 Apr 26; 296(5568):733-5.
Hinnebusch BJ, Rudolph AE, Cherepanov P, Dixon JE, Schwan TG, Forsberg A. PMID: 11976454.
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PubMed Mentions:
137 Fields:
Translation:
AnimalsCellsPHPublic Health
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Yersinia effectors target mammalian signalling pathways. Cell Microbiol. 2002 Apr; 4(4):201-11.
Juris SJ, Shao F, Dixon JE. PMID: 11952637.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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The archetype STYX/dead-phosphatase complexes with a spermatid mRNA-binding protein and is essential for normal sperm production. Proc Natl Acad Sci U S A. 2002 Feb 19; 99(4):2112-7.
Wishart MJ, Dixon JE. PMID: 11842224; PMCID: PMC122327.
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PubMed Mentions:
31 Fields:
Translation:
HumansAnimalsCells
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Cloning, expression, and characterization of the Galalpha 1,3Gal high affinity lectin from the mushroom Marasmius oreades. J Biol Chem. 2002 Apr 26; 277(17):15002-5.
Kruger RP, Winter HC, Simonson-Leff N, Stuckey JA, Goldstein IJ, Dixon JE. PMID: 11836254.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Drosophila Ack targets its substrate, the sorting nexin DSH3PX1, to a protein complex involved in axonal guidance. J Biol Chem. 2002 Mar 15; 277(11):9422-8.
Worby CA, Simonson-Leff N, Clemens JC, Huddler D, Muda M, Dixon JE. PMID: 11773052.
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PubMed Mentions:
15 Fields:
Translation:
AnimalsCells
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A unique carbohydrate binding domain targets the lafora disease phosphatase to glycogen. J Biol Chem. 2002 Jan 25; 277(4):2377-80.
Wang J, Stuckey JA, Wishart MJ, Dixon JE. PMID: 11739371.
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PubMed Mentions:
66 Fields:
Translation:
HumansAnimalsCells
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Myotubularin and MTMR2, phosphatidylinositol 3-phosphatases mutated in myotubular myopathy and type 4B Charcot-Marie-Tooth disease. J Biol Chem. 2002 Feb 08; 277(6):4526-31.
Kim SA, Taylor GS, Torgersen KM, Dixon JE. PMID: 11733541.
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PubMed Mentions:
48 Fields:
Translation:
HumansAnimalsCells
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PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem. 2002 Feb 15; 277(7):5484-9.
Mayo LD, Dixon JE, Durden DL, Tonks NK, Donner DB. PMID: 11729185.
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PubMed Mentions:
112 Fields:
Translation:
HumansCells
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The sorting nexin, DSH3PX1, connects the axonal guidance receptor, Dscam, to the actin cytoskeleton. J Biol Chem. 2001 Nov 09; 276(45):41782-9.
Worby CA, Simonson-Leff N, Clemens JC, Kruger RP, Muda M, Dixon JE. PMID: 11546816.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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RNA interference of gene expression (RNAi) in cultured Drosophila cells. Sci STKE. 2001 Aug 14; 2001(95):pl1.
Worby CA, Simonson-Leff N, Dixon JE. PMID: 11752672.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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An assay for phosphoinositide phosphatases utilizing fluorescent substrates. Anal Biochem. 2001 Aug 01; 295(1):122-6.
Taylor GS, Dixon JE. PMID: 11476556.
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PubMed Mentions:
16 Fields:
Translation:
Cells
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Phoxy lipids: revealing PX domains as phosphoinositide binding modules. Cell. 2001 Jun 29; 105(7):817-20.
Wishart MJ, Taylor GS, Dixon JE. PMID: 11439176.
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PubMed Mentions:
37 Fields:
Translation:
Cells
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The PTEN tumor suppressor protein inhibits tumor necrosis factor-induced nuclear factor kappa B activity. J Biol Chem. 2001 Jul 20; 276(29):27740-4.
Gustin JA, Maehama T, Dixon JE, Donner DB. PMID: 11356844.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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A phosphatidylinositol 3-kinase/Akt/mTOR pathway mediates and PTEN antagonizes tumor necrosis factor inhibition of insulin signaling through insulin receptor substrate-1. Proc Natl Acad Sci U S A. 2001 Apr 10; 98(8):4640-5.
Ozes ON, Akca H, Mayo LD, Gustin JA, Maehama T, Dixon JE, Donner DB. PMID: 11287630; PMCID: PMC31887.
View in:
PubMed Mentions:
148 Fields:
Translation:
HumansCells
-
ERK7 is an autoactivated member of the MAPK family. J Biol Chem. 2001 Jun 15; 276(24):21272-9.
Abe MK, Kahle KT, Saelzler MP, Orth K, Dixon JE, Rosner MR. PMID: 11287416.
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PubMed Mentions:
33 Fields:
Translation:
AnimalsCells
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PTEN and myotubularin phosphoinositide phosphatases: bringing bioinformatics to the lab bench. Curr Opin Cell Biol. 2001 Apr; 13(2):172-81.
Wishart MJ, Taylor GS, Slama JT, Dixon JE. PMID: 11248551.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Alternative splicing of KCNQ2 potassium channel transcripts contributes to the functional diversity of M-currents. J Physiol. 2001 Mar 01; 531(Pt 2):347-58.
Pan Z, Selyanko AA, Hadley JK, Brown DA, Dixon JE, McKinnon D. PMID: 11230508; PMCID: PMC2278468.
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PubMed Mentions:
21 Fields:
Translation:
AnimalsCells
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PTEN and myotubularin: novel phosphoinositide phosphatases. Annu Rev Biochem. 2001; 70:247-79.
Maehama T, Taylor GS, Dixon JE. PMID: 11395408.
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PubMed Mentions:
168 Fields:
Translation:
HumansAnimals
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Disruption of signaling by Yersinia effector YopJ, a ubiquitin-like protein protease. Science. 2000 Nov 24; 290(5496):1594-7.
Orth K, Xu Z, Mudgett MB, Bao ZQ, Palmer LE, Bliska JB, Mangel WF, Staskawicz B, Dixon JE. PMID: 11090361.
View in:
PubMed Mentions:
194 Fields:
Translation:
HumansAnimalsCells
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[PTEN tumor suppressor: functions as a lipid phosphatase]. Tanpakushitsu Kakusan Koso. 2000 Oct; 45(14):2405-14.
Maehama T, Dixon JE. PMID: 11051842.
View in:
PubMed Mentions:
3 Fields:
Translation:
HumansAnimalsCells
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A distinctive role for the Yersinia protein kinase: actin binding, kinase activation, and cytoskeleton disruption. Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17):9431-6.
Juris SJ, Rudolph AE, Huddler D, Orth K, Dixon JE. PMID: 10920208; PMCID: PMC16881.
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PubMed Mentions:
71 Fields:
Translation:
HumansAnimalsCells
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The crystal structure of adenylosuccinate lyase from Pyrobaculum aerophilum reveals an intracellular protein with three disulfide bonds. J Mol Biol. 2000 Aug 11; 301(2):433-50.
Toth EA, Worby C, Dixon JE, Goedken ER, Marqusee S, Yeates TO. PMID: 10926519.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Myotubularin, a protein tyrosine phosphatase mutated in myotubular myopathy, dephosphorylates the lipid second messenger, phosphatidylinositol 3-phosphate. Proc Natl Acad Sci U S A. 2000 Aug 01; 97(16):8910-5.
Taylor GS, Maehama T, Dixon JE. PMID: 10900271; PMCID: PMC16795.
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PubMed Mentions:
141 Fields:
Translation:
HumansCells
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Drosophila Dscam is an axon guidance receptor exhibiting extraordinary molecular diversity. Cell. 2000 Jun 09; 101(6):671-84.
Schmucker D, Clemens JC, Shu H, Worby CA, Xiao J, Muda M, Dixon JE, Zipursky SL. PMID: 10892653.
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PubMed Mentions:
376 Fields:
Translation:
HumansAnimalsCells
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Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways. Proc Natl Acad Sci U S A. 2000 Jun 06; 97(12):6499-503.
Clemens JC, Worby CA, Simonson-Leff N, Muda M, Maehama T, Hemmings BA, Dixon JE. PMID: 10823906; PMCID: PMC18635.
View in:
PubMed Mentions:
327 Fields:
Translation:
AnimalsCells
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A sodium channel signaling complex: modulation by associated receptor protein tyrosine phosphatase beta. Nat Neurosci. 2000 May; 3(5):437-44.
Ratcliffe CF, Qu Y, McCormick KA, Tibbs VC, Dixon JE, Scheuer T, Catterall WA. PMID: 10769382.
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PubMed Mentions:
62 Fields:
Translation:
HumansAnimalsCells
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A sensitive assay for phosphoinositide phosphatases. Anal Biochem. 2000 Mar 15; 279(2):248-50.
Maehama T, Taylor GS, Slama JT, Dixon JE. PMID: 10706796.
View in:
PubMed Mentions:
49 Fields:
Translation:
Humans
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ERBB-2 overexpression confers PI 3' kinase-dependent invasion capacity on human mammary epithelial cells. Br J Cancer. 2000 Feb; 82(3):666-74.
Ignatoski KM, Maehama T, Markwart SM, Dixon JE, Livant DL, Ethier SP. PMID: 10682681; PMCID: PMC2363331.
View in:
PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases. Semin Immunol. 2000 Feb; 12(1):75-84.
Li L, Dixon JE. PMID: 10723800.
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PubMed Mentions:
21 Fields:
Translation:
HumansAnimalsCells
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The human Cdc14 phosphatases interact with and dephosphorylate the tumor suppressor protein p53. J Biol Chem. 2000 Jan 28; 275(4):2410-4.
Li L, Ljungman M, Dixon JE. PMID: 10644693.
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PubMed Mentions:
28 Fields:
Translation:
HumansAnimalsCells
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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association. Cell. 1999 Oct 29; 99(3):323-34.
Lee JO, Yang H, Georgescu MM, Di Cristofano A, Maehama T, Shi Y, Dixon JE, Pandolfi P, Pavletich NP. PMID: 10555148.
View in:
PubMed Mentions:
445 Fields:
Translation:
HumansAnimalsCells
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Inhibition of the mitogen-activated protein kinase kinase superfamily by a Yersinia effector. Science. 1999 Sep 17; 285(5435):1920-3.
Orth K, Palmer LE, Bao ZQ, Stewart S, Rudolph AE, Bliska JB, Dixon JE. PMID: 10489373.
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PubMed Mentions:
133 Fields:
Translation:
HumansCells
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Identification of the human YVH1 protein-tyrosine phosphatase orthologue reveals a novel zinc binding domain essential for in vivo function. J Biol Chem. 1999 Aug 20; 274(34):23991-5.
Muda M, Manning ER, Orth K, Dixon JE. PMID: 10446167.
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PubMed Mentions:
14 Fields:
Translation:
HumansAnimalsCells
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Distribution and prevalence of hyperpolarization-activated cation channel (HCN) mRNA expression in cardiac tissues. Circ Res. 1999 Jul 09; 85(1):e1-6.
Shi W, Wymore R, Yu H, Wu J, Wymore RT, Pan Z, Robinson RB, Dixon JE, McKinnon D, Cohen IS. PMID: 10400919.
View in:
PubMed Mentions:
134 Fields:
Translation:
Animals
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Expression, characterization, and mutagenesis of the Yersinia pestis murine toxin, a phospholipase D superfamily member. J Biol Chem. 1999 Apr 23; 274(17):11824-31.
Rudolph AE, Stuckey JA, Zhao Y, Matthews HR, Patton WA, Moss J, Dixon JE. PMID: 10207000.
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PubMed Mentions:
36 Fields:
Translation:
AnimalsCells
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Isoform-specific regulation of the sodium pump by alpha- and beta-adrenergic agonists in the guinea-pig ventricle. J Physiol. 1999 Apr 15; 516 ( Pt 2):377-83.
Gao J, Wymore R, Wymore RT, Wang Y, McKinnon D, Dixon JE, Mathias RT, Cohen IS, Baldo GJ. PMID: 10087338; PMCID: PMC2269277.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Transient outward current, Ito1, is altered in cardiac memory. Circulation. 1999 Apr 13; 99(14):1898-905.
Yu H, McKinnon D, Dixon JE, Gao J, Wymore R, Cohen IS, Danilo P, Shvilkin A, Anyukhovsky EP, Sosunov EA, Hara M, Rosen MR. PMID: 10199889.
View in:
PubMed Mentions:
27 Fields:
Translation:
Animals
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PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol. 1999 Apr; 9(4):125-8.
Maehama T, Dixon JE. PMID: 10203785.
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PubMed Mentions:
186 Fields:
Translation:
HumansAnimalsCells
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Crystal structure of a phospholipase D family member. Nat Struct Biol. 1999 Mar; 6(3):278-84.
Stuckey JA, Dixon JE. PMID: 10074947.
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PubMed Mentions:
74 Fields:
Translation:
HumansCells
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His68 and His141 are critical contributors to the intersubunit catalytic site of adenylosuccinate lyase of Bacillus subtilis. Biochemistry. 1999 Jan 05; 38(1):22-32.
Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF. PMID: 9890879.
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PubMed Mentions:
11 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatases: mechanisms of catalysis and regulation. Curr Opin Chem Biol. 1998 Oct; 2(5):633-41.
Denu JM, Dixon JE. PMID: 9818190.
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PubMed Mentions:
112 Fields:
Translation:
Cells
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Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia. J Physiol. 1998 Sep 15; 511 ( Pt 3):675-82.
Shi W, Wang HS, Pan Z, Wymore RS, Cohen IS, McKinnon D, Dixon JE. PMID: 9714851; PMCID: PMC2231163.
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PubMed Mentions:
19 Fields:
Translation:
Animals
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Catalytic mechanism of the phospholipase D superfamily proceeds via a covalent phosphohistidine intermediate. Proc Natl Acad Sci U S A. 1998 Aug 04; 95(16):9202-7.
Gottlin EB, Rudolph AE, Zhao Y, Matthews HR, Dixon JE. PMID: 9689058; PMCID: PMC21316.
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PubMed Mentions:
42 Fields:
Translation:
HumansCells
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Gathering STYX: phosphatase-like form predicts functions for unique protein-interaction domains. Trends Biochem Sci. 1998 Aug; 23(8):301-6.
Wishart MJ, Dixon JE. PMID: 9757831.
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PubMed Mentions:
52 Fields:
Translation:
AnimalsCells
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A common requirement for the catalytic activity and both SH2 domains of SHP-2 in mitogen-activated protein (MAP) kinase activation by the ErbB family of receptors. A specific role for SHP-2 in map, but not c-Jun amino-terminal kinase activation. J Biol Chem. 1998 Jul 03; 273(27):16643-6.
Deb TB, Wong L, Salomon DS, Zhou G, Dixon JE, Gutkind JS, Thompson SA, Johnson GR. PMID: 9642214.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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Implication of His68 in the substrate site of Bacillus subtilis adenylosuccinate lyase by mutagenesis and affinity labeling with 2-[(4-bromo-2,3-dioxobutyl)thio]adenosine 5'-monophosphate. Biochemistry. 1998 Jun 09; 37(23):8481-9.
Lee TT, Worby C, Bao ZQ, Dixon JE, Colman RF. PMID: 9622500.
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PubMed Mentions:
8 Fields:
Translation:
Cells
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RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase. J Biol Chem. 1998 Jun 05; 273(23):14309-14.
Bell SD, Denu JM, Dixon JE, Ellington AD. PMID: 9603938.
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PubMed Mentions:
11 Fields:
Translation:
Cells
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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem. 1998 May 29; 273(22):13375-8.
Maehama T, Dixon JE. PMID: 9593664.
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PubMed Mentions:
1156 Fields:
Translation:
HumansCells
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Identification and characterization of GFRalpha-3, a novel Co-receptor belonging to the glial cell line-derived neurotrophic receptor family. J Biol Chem. 1998 Feb 06; 273(6):3502-8.
Worby CA, Vega QC, Chao HH, Seasholtz AF, Thompson RC, Dixon JE. PMID: 9452475.
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PubMed Mentions:
20 Fields:
Translation:
HumansAnimalsCells
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Effects of sulfhydryl regents on the activity of lambda Ser/Thr phosphoprotein phosphatase and inhibition of the enzyme by zinc ion. Protein Eng. 1997 Dec; 10(12):1445-52.
Zhuo S, Dixon JE. PMID: 9543006.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Expression, characterization, and crystallization of a member of the novel phospholipase D family of phosphodiesterases. Protein Sci. 1997 Dec; 6(12):2655-8.
Zhao Y, Stuckey JA, Lohse DL, Dixon JE. PMID: 9416618; PMCID: PMC2143608.
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PubMed Mentions:
18 Fields:
Translation:
Cells
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A family of putative tumor suppressors is structurally and functionally conserved in humans and yeast. J Biol Chem. 1997 Nov 21; 272(47):29403-6.
Li L, Ernsting BR, Wishart MJ, Lohse DL, Dixon JE. PMID: 9367992.
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PubMed Mentions:
57 Fields:
Translation:
HumansAnimalsCells
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Differential accumulation of DPTP61F alternative transcripts: regulation of a protein tyrosine phosphatase by segmentation genes. Mech Dev. 1997 Jul; 65(1-2):19-30.
Ursuliak Z, Clemens JC, Dixon JE, Price JV. PMID: 9256342.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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PTP NE-6: a brain-enriched receptor-type protein tyrosine phosphatase with a divergent catalytic domain. J Neurochem. 1997 May; 68(5):1820-9.
Fitzgerald LR, Walton KM, Dixon JE, Largent BL. PMID: 9109506.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1. Biochemistry. 1997 Apr 15; 36(15):4568-75.
Lohse DL, Denu JM, Santoro N, Dixon JE. PMID: 9109666.
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PubMed Mentions:
35 Fields:
Translation:
HumansAnimalsCells
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The PPS1 gene of Saccharomyces cerevisiae codes for a dual specificity protein phosphatase with a role in the DNA synthesis phase of the cell cycle. J Biol Chem. 1997 Apr 04; 272(14):9332-43.
Ernsting BR, Dixon JE. PMID: 9083070.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimalsCells
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Tissue and species distribution of mRNA for the IKr-like K+ channel, erg. Circ Res. 1997 Feb; 80(2):261-8.
Wymore RS, Gintant GA, Wymore RT, Dixon JE, McKinnon D, Cohen IS. PMID: 9012748.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Identification of His141 in the active site of Bacillus subtilis adenylosuccinate lyase by affinity labeling with 6-(4-bromo-2,3-dioxobutyl)thioadenosine 5'-monophosphate. J Biol Chem. 1997 Jan 03; 272(1):458-65.
Lee TT, Worby C, Dixon JE, Colman RF. PMID: 8995283.
View in:
PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Purification and kinetic characterization of the mitogen-activated protein kinase phosphatase rVH6. J Biol Chem. 1996 Dec 27; 271(52):33486-92.
Wiland AM, Denu JM, Mourey RJ, Dixon JE. PMID: 8969212.
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PubMed Mentions:
7 Fields:
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Form and function in protein dephosphorylation. Cell. 1996 Nov 01; 87(3):361-4.
Denu JM, Stuckey JA, Saper MA, Dixon JE. PMID: 8898189.
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PubMed Mentions:
74 Fields:
Translation:
AnimalsCells
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Kinetic analysis of the catalytic domain of human cdc25B. J Biol Chem. 1996 Nov 01; 271(44):27445-9.
Gottlin EB, Xu X, Epstein DM, Burke SP, Eckstein JW, Ballou DP, Dixon JE. PMID: 8910325.
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PubMed Mentions:
19 Fields:
Translation:
HumansCells
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Role of the Kv4.3 K+ channel in ventricular muscle. A molecular correlate for the transient outward current. Circ Res. 1996 Oct; 79(4):659-68.
Dixon JE, Shi W, Wang HS, McDonald C, Yu H, Wymore RS, Cohen IS, McKinnon D. PMID: 8831489.
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PubMed Mentions:
134 Fields:
Translation:
HumansAnimalsCells
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Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesis. Proc Natl Acad Sci U S A. 1996 Oct 01; 93(20):10657-61.
Vega QC, Worby CA, Lechner MS, Dixon JE, Dressler GR. PMID: 8855235; PMCID: PMC38210.
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PubMed Mentions:
65 Fields:
Translation:
AnimalsCells
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Glial cell line-derived neurotrophic factor signals through the RET receptor and activates mitogen-activated protein kinase. J Biol Chem. 1996 Sep 27; 271(39):23619-22.
Worby CA, Vega QC, Zhao Y, Chao HH, Seasholtz AF, Dixon JE. PMID: 8798576.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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A Drosophila protein-tyrosine phosphatase associates with an adapter protein required for axonal guidance. J Biol Chem. 1996 Jul 19; 271(29):17002-5.
Clemens JC, Ursuliak Z, Clemens KK, Price JV, Dixon JE. PMID: 8663600.
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PubMed Mentions:
15 Fields:
Translation:
HumansAnimalsCells
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The SH2 domain-containing tyrosine phosphatase PTP1D is required for interferon alpha/beta-induced gene expression. J Biol Chem. 1996 Jul 05; 271(27):15862-5.
David M, Zhou G, Pine R, Dixon JE, Larner AC. PMID: 8663536.
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PubMed Mentions:
15 Fields:
Translation:
HumansCells
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Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis. Biochemistry. 1996 Jun 04; 35(22):7084-92.
Hengge AC, Denu JM, Dixon JE. PMID: 8679534.
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PubMed Mentions:
12 Fields:
Translation:
HumansCells
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Crystal structure of the dual specificity protein phosphatase VHR. Science. 1996 May 31; 272(5266):1328-31.
Yuvaniyama J, Denu JM, Dixon JE, Saper MA. PMID: 8650541.
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PubMed Mentions:
87 Fields:
Translation:
HumansCells
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Direct association between the Ret receptor tyrosine kinase and the Src homology 2-containing adapter protein Grb7. J Biol Chem. 1996 May 03; 271(18):10607-10.
Pandey A, Liu X, Dixon JE, Di Fiore PP, Dixit VM. PMID: 8631863.
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PubMed Mentions:
20 Fields:
Translation:
Cells
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Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis. Proc Natl Acad Sci U S A. 1996 Mar 19; 93(6):2493-8.
Denu JM, Lohse DL, Vijayalakshmi J, Saper MA, Dixon JE. PMID: 8637902; PMCID: PMC39825.
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PubMed Mentions:
59 Fields:
Translation:
AnimalsCells
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Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities. J Biol Chem. 1996 Mar 08; 271(10):5309-12.
Liu X, Vega QC, Decker RA, Pandey A, Worby CA, Dixon JE. PMID: 8621380.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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Parathyroid hormone regulates the expression of the receptor protein tyrosine phosphatase, OST-PTP, in rat osteoblast-like cells. Endocrinology. 1996 Mar; 137(3):925-33.
Mauro LJ, Olmsted EA, Davis AR, Dixon JE. PMID: 8603605.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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A novel cytoplasmic dual specificity protein tyrosine phosphatase implicated in muscle and neuronal differentiation. J Biol Chem. 1996 Feb 16; 271(7):3795-802.
Mourey RJ, Vega QC, Campbell JS, Wenderoth MP, Hauschka SD, Krebs EG, Dixon JE. PMID: 8631996.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Selective activation of MEK1 but not MEK2 by A-Raf from epidermal growth factor-stimulated Hela cells. J Biol Chem. 1996 Feb 09; 271(6):3265-71.
Wu X, Noh SJ, Zhou G, Dixon JE, Guan KL. PMID: 8621729.
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PubMed Mentions:
29 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatases: their roles in signal transduction. Recent Prog Horm Res. 1996; 51:405-14; discussion 415.
Dixon JE. PMID: 8701088.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Potassium channel mRNA expression in prevertebral and paravertebral sympathetic neurons. Eur J Neurosci. 1996 Jan; 8(1):183-91.
Dixon JE, McKinnon D. PMID: 8713462.
View in:
PubMed Mentions:
18 Translation:
AnimalsCells
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A single mutation converts a novel phosphotyrosine binding domain into a dual-specificity phosphatase. J Biol Chem. 1995 Nov 10; 270(45):26782-5.
Wishart MJ, Denu JM, Williams JA, Dixon JE. PMID: 7592916.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Insights derived from the structures of the Ser/Thr phosphatases calcineurin and protein phosphatase 1. Structure. 1995 Oct 15; 3(10):987-90.
Lohse DL, Denu JM, Dixon JE. PMID: 8590008.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase. J Neurochem. 1995 Oct; 65(4):1823-33.
Martell KJ, Seasholtz AF, Kwak SP, Clemens KK, Dixon JE. PMID: 7561881.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Structure and catalytic properties of protein tyrosine phosphatases. Ann N Y Acad Sci. 1995 Sep 07; 766:18-22.
Dixon JE. PMID: 7486654.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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A ligand-induced conformational change in the Yersinia protein tyrosine phosphatase. Protein Sci. 1995 Sep; 4(9):1904-13.
Schubert HL, Fauman EB, Stuckey JA, Dixon JE, Saper MA. PMID: 8528087; PMCID: PMC2143214.
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PubMed Mentions:
25 Fields:
Translation:
Cells
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A catalytic mechanism for the dual-specific phosphatases. Proc Natl Acad Sci U S A. 1995 Jun 20; 92(13):5910-4.
Denu JM, Dixon JE. PMID: 7597052; PMCID: PMC41611.
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PubMed Mentions:
51 Fields:
Translation:
Cells
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Components of a new human protein kinase signal transduction pathway. J Biol Chem. 1995 May 26; 270(21):12665-9.
Zhou G, Bao ZQ, Dixon JE. PMID: 7759517.
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PubMed Mentions:
190 Fields:
Translation:
HumansAnimalsCells
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The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase. Biochemistry. 1995 Mar 14; 34(10):3396-403.
Denu JM, Zhou G, Guo Y, Dixon JE. PMID: 7880835.
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PubMed Mentions:
20 Fields:
Translation:
HumansCells
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The purification and characterization of a human dual-specific protein tyrosine phosphatase. J Biol Chem. 1995 Feb 24; 270(8):3796-803.
Denu JM, Zhou G, Wu L, Zhao R, Yuvaniyama J, Saper MA, Dixon JE. PMID: 7876121.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Multiple dual specificity protein tyrosine phosphatases are expressed and regulated differentially in liver cell lines. J Biol Chem. 1995 Jan 20; 270(3):1156-60.
Kwak SP, Dixon JE. PMID: 7836374.
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PubMed Mentions:
26 Fields:
Translation:
AnimalsCells
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The Cys(X)5Arg catalytic motif in phosphoester hydrolysis. Biochemistry. 1994 Dec 27; 33(51):15266-70.
Zhang ZY, Wang Y, Wu L, Fauman EB, Stuckey JA, Schubert HL, Saper MA, Dixon JE. PMID: 7803389.
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PubMed Mentions:
49 Fields:
Translation:
Cells
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Protein-tyrosine phosphatases. J Biol Chem. 1994 Dec 16; 269(50):31323-6.
Stone RL, Dixon JE. PMID: 7989293.
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PubMed Mentions:
45 Fields:
Translation:
HumansAnimalsCells
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Identification of a hormonally regulated protein tyrosine phosphatase associated with bone and testicular differentiation. J Biol Chem. 1994 Dec 02; 269(48):30659-67.
Mauro LJ, Olmsted EA, Skrobacz BM, Mourey RJ, Davis AR, Dixon JE. PMID: 7527035.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Protein tyrosine phosphatases in disease processes. Trends Cell Biol. 1994 Dec; 4(12):427-30.
Ninfa EG, Dixon JE. PMID: 14731691.
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PubMed Mentions:
1 Fields:
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Distribution and regulation of the candidate prohormone processing enzymes SPC2 and SPC3 in adult rat brain. Neuropeptides. 1994 Dec; 27(6):307-22.
Birch NP, Hakes DJ, Dixon JE, Mezey E. PMID: 7898639.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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The catalytic role of Cys124 in the dual specificity phosphatase VHR. J Biol Chem. 1994 Nov 11; 269(45):28084-90.
Zhou G, Denu JM, Wu L, Dixon JE. PMID: 7961745.
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PubMed Mentions:
23 Fields:
Translation:
HumansCells
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Resolution of immobile chi structures by the FLP recombinase of 2 microns plasmid. J Mol Biol. 1994 Oct 21; 243(2):199-207.
Dixon JE, Sadowski PD. PMID: 7932750.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Mutational analysis of a Ser/Thr phosphatase. Identification of residues important in phosphoesterase substrate binding and catalysis. J Biol Chem. 1994 Oct 21; 269(42):26234-8.
Zhuo S, Clemens JC, Stone RL, Dixon JE. PMID: 7929339.
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PubMed Mentions:
55 Fields:
Translation:
Cells
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Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate. Nature. 1994 Aug 18; 370(6490):571-5.
Stuckey JA, Schubert HL, Fauman EB, Zhang ZY, Dixon JE, Saper MA. PMID: 8052312.
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PubMed Mentions:
92 Fields:
Translation:
Cells
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Chromosomal localization of four human VH1-like protein-tyrosine phosphatases. Genomics. 1994 Jul 15; 22(2):462-4.
Martell KJ, Kwak S, Hakes DJ, Dixon JE, Trent JM. PMID: 7806236.
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PubMed Mentions:
5 Fields:
Translation:
HumansCells
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'Zip codes' direct intracellular protein tyrosine phosphatases to the correct cellular 'address'. Trends Biochem Sci. 1994 Apr; 19(4):151-5.
Mauro LJ, Dixon JE. PMID: 8016862.
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PubMed Mentions:
34 Fields:
Translation:
HumansAnimalsCells
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Nature of the rate-determining steps of the reaction catalyzed by the Yersinia protein-tyrosine phosphatase. J Biol Chem. 1994 Mar 18; 269(11):8140-5.
Zhang ZY, Malachowski WP, Van Etten RL, Dixon JE. PMID: 8132539.
View in:
PubMed Mentions:
15 Fields:
Translation:
Cells
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Dissecting the catalytic mechanism of protein-tyrosine phosphatases. Proc Natl Acad Sci U S A. 1994 Mar 01; 91(5):1624-7.
Zhang ZY, Wang Y, Dixon JE. PMID: 8127855; PMCID: PMC43215.
View in:
PubMed Mentions:
76 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatase substrate specificity: size and phosphotyrosine positioning requirements in peptide substrates. Biochemistry. 1994 Mar 01; 33(8):2285-90.
Zhang ZY, Maclean D, McNamara DJ, Sawyer TK, Dixon JE. PMID: 7509638.
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PubMed Mentions:
37 Fields:
Translation:
AnimalsCells
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Two genes for de novo purine nucleotide synthesis on human chromosome 4 are closely linked and divergently transcribed. J Biol Chem. 1994 Feb 18; 269(7):5313-21.
Brayton KA, Chen Z, Zhou G, Nagy PL, Gavalas A, Trent JM, Deaven LL, Dixon JE, Zalkin H. PMID: 8106516.
View in:
PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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Isolation and characterization of a human dual specificity protein-tyrosine phosphatase gene. J Biol Chem. 1994 Feb 04; 269(5):3596-604.
Kwak SP, Hakes DJ, Martell KJ, Dixon JE. PMID: 8106404.
View in:
PubMed Mentions:
49 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatases: characterization of extracellular and intracellular domains. Curr Opin Genet Dev. 1994 Feb; 4(1):31-9.
Mourey RJ, Dixon JE. PMID: 8193537.
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PubMed Mentions:
6 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatases: mechanism of catalysis and substrate specificity. Adv Enzymol Relat Areas Mol Biol. 1994; 68:1-36.
Zhang ZY, Dixon JE. PMID: 8154323.
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PubMed Mentions:
23 Fields:
Translation:
HumansAnimalsCells
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Resolution of synthetic chi structures by the FLP site-specific recombinase. J Mol Biol. 1993 Dec 05; 234(3):522-33.
Dixon JE, Sadowski PD. PMID: 8254657.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Bacterial and viral protein tyrosine phosphatases. Semin Cell Biol. 1993 Dec; 4(6):389-96.
Guan KL, Dixon JE. PMID: 8305677.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Purification and characterization of the candidate prohormone-processing enzyme SPC3 produced in a mouse L cell line. J Biol Chem. 1993 Sep 25; 268(27):20291-8.
Rufaut NW, Brennan SO, Hakes DJ, Dixon JE, Birch NP. PMID: 8376387.
View in:
PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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Expression, purification, and kinetic characterization of recombinant human adenylosuccinate lyase. J Biol Chem. 1993 Sep 15; 268(26):19710-6.
Stone RL, Zalkin H, Dixon JE. PMID: 8366112.
View in:
PubMed Mentions:
17 Fields:
Translation:
HumansCells
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Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402. Biochemistry. 1993 Sep 14; 32(36):9340-5.
Zhang ZY, Dixon JE. PMID: 8369304.
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PubMed Mentions:
68 Fields:
Translation:
Cells
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Expression, purification, crystallization, and biochemical characterization of a recombinant protein phosphatase. J Biol Chem. 1993 Aug 25; 268(24):17754-61.
Zhuo S, Clemens JC, Hakes DJ, Barford D, Dixon JE. PMID: 8394350.
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PubMed Mentions:
47 Fields:
Translation:
Cells
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Expression, purification, and characterization of CTP:glycerol-3-phosphate cytidylyltransferase from Bacillus subtilis. J Biol Chem. 1993 Aug 05; 268(22):16648-54.
Park YS, Sweitzer TD, Dixon JE, Kent C. PMID: 8393871.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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A novel receptor-type protein tyrosine phosphatase is expressed during neurogenesis in the olfactory neuroepithelium. Neuron. 1993 Aug; 11(2):387-400.
Walton KM, Martell KJ, Kwak SP, Dixon JE, Largent BL. PMID: 8352946.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Tissue-specific and substrate-specific endoproteolytic cleavage of monkey pro-opiomelanocortin in heterologous endocrine cells: processing at Lys-Lys dibasic pairs. Neuroendocrinology. 1993 Jul; 58(1):94-105.
Lin HL, Day NC, Ueda Y, Martin DK, Dixon JE, Seidah NG, Akil H. PMID: 7903430.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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A continuous spectrophotometric and fluorimetric assay for protein tyrosine phosphatase using phosphotyrosine-containing peptides. Anal Biochem. 1993 May 15; 211(1):7-15.
Zhang ZY, Maclean D, Thieme-Sefler AM, Roeske RW, Dixon JE. PMID: 7686722.
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PubMed Mentions:
35 Fields:
Translation:
Cells
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Substrate specificity of the protein tyrosine phosphatases. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4446-50.
Zhang ZY, Thieme-Sefler AM, Maclean D, McNamara DJ, Dobrusin EM, Sawyer TK, Dixon JE. PMID: 7685104; PMCID: PMC46528.
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PubMed Mentions:
57 Fields:
Translation:
Cells
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A protein phosphatase related to the vaccinia virus VH1 is encoded in the genomes of several orthopoxviruses and a baculovirus. Proc Natl Acad Sci U S A. 1993 May 01; 90(9):4017-21.
Hakes DJ, Martell KJ, Zhao WG, Massung RF, Esposito JJ, Dixon JE. PMID: 8387208; PMCID: PMC46437.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Alternative splicing gives rise to a nuclear protein tyrosine phosphatase in Drosophila. J Biol Chem. 1993 Apr 05; 268(10):6839-42.
McLaughlin S, Dixon JE. PMID: 8463208.
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PubMed Mentions:
19 Fields:
Translation:
HumansAnimalsCells
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In vitro activation of the transcription factor ISGF3 by interferon alpha involves a membrane-associated tyrosine phosphatase and tyrosine kinase. J Biol Chem. 1993 Mar 25; 268(9):6593-9.
David M, Romero G, Zhang ZY, Dixon JE, Larner AC. PMID: 8454630.
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PubMed Mentions:
26 Fields:
Translation:
HumansCells
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Binding constant determination studies utilizing recombinant delta CREB protein. DNA Cell Biol. 1993 Mar; 12(2):183-90.
Williams JS, Dixon JE, Andrisani OM. PMID: 8471166.
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PubMed Mentions:
6 Fields:
Translation:
Cells
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Mutations of the FLP recombinase gene that cause a deficiency in DNA bending and strand cleavage. J Biol Chem. 1993 Jan 15; 268(2):1101-8.
Kulpa J, Dixon JE, Pan G, Sadowski PD. PMID: 8419317.
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PubMed Mentions:
6 Fields:
Translation:
AnimalsCells
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Protein tyrosine phosphatases. Annu Rev Biochem. 1993; 62:101-20.
Walton KM, Dixon JE. PMID: 8352585.
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PubMed Mentions:
81 Fields:
Translation:
AnimalsCells
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The yeast open reading frame encoding a dual specificity phosphatase. Trends Biochem Sci. 1993 Jan; 18(1):6.
Guan K, Hakes D, Dixon JE, Park HD, Cooper TG. PMID: 8438236.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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A yeast protein phosphatase related to the vaccinia virus VH1 phosphatase is induced by nitrogen starvation. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):12175-9.
Guan K, Hakes DJ, Wang Y, Park HD, Cooper TG, Dixon JE. PMID: 1334559; PMCID: PMC50721.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Negative regulation of mitosis by two functionally overlapping PTPases in fission yeast. EMBO J. 1992 Dec; 11(13):4943-52.
Millar JB, Russell P, Dixon JE, Guan KL. PMID: 1464319; PMCID: PMC556972.
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PubMed Mentions:
27 Fields:
Translation:
AnimalsCells
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The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage. J Exp Med. 1992 Dec 01; 176(6):1625-30.
Bliska JB, Clemens JC, Dixon JE, Falkow S. PMID: 1281213; PMCID: PMC2119465.
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PubMed Mentions:
48 Fields:
Translation:
AnimalsCells
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Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase. J Biol Chem. 1992 Nov 25; 267(33):23759-66.
Zhang ZY, Clemens JC, Schubert HL, Stuckey JA, Fischer MW, Hume DM, Saper MA, Dixon JE. PMID: 1429715.
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PubMed Mentions:
60 Fields:
Translation:
Cells
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cAMP-dependent protein kinase, but not the cGMP-dependent enzyme, rapidly phosphorylates delta-CREB, and a synthetic delta-CREB peptide. Biochem Cell Biol. 1992 Oct-Nov; 70(10-11):1277-82.
Colbran JL, Roach PJ, Fiol CJ, Dixon JE, Andrisani OM, Corbin JD. PMID: 1338414.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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Expression, purification, and characterization of the functional dimeric cytoplasmic domain of human erythrocyte band 3 in Escherichia coli. Protein Sci. 1992 Sep; 1(9):1206-14.
Wang CC, Badylak JA, Lux SE, Moriyama R, Dixon JE, Low PS. PMID: 1304397; PMCID: PMC2142179.
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PubMed Mentions:
10 Fields:
Translation:
HumansCells
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A thousand and two protein tyrosine phosphatases. Biochim Biophys Acta. 1992 Jul 22; 1136(1):35-43.
Pot DA, Dixon JE. PMID: 1643113.
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PubMed Mentions:
26 Fields:
Translation:
HumansAnimalsCells
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Cloning and characterization of the cDNA encoding human adenylosuccinate synthetase. FEBS Lett. 1992 May 25; 303(1):4-10.
Powell SM, Zalkin H, Dixon JE. PMID: 1592113.
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PubMed Mentions:
3 Fields:
Translation:
HumansCells
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Isolation and characterization of a second protein tyrosine phosphatase gene, PTP2, from Saccharomyces cerevisiae. J Biol Chem. 1992 May 15; 267(14):10024-30.
Guan K, Deschenes RJ, Dixon JE. PMID: 1577774.
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PubMed Mentions:
12 Fields:
Translation:
HumansAnimalsCells
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New vectors for high level expression of recombinant proteins in bacteria. Anal Biochem. 1992 May 01; 202(2):293-8.
Hakes DJ, Dixon JE. PMID: 1519755.
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PubMed Mentions:
71 Fields:
Translation:
Cells
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Conserved histidine residues in soybean lipoxygenase: functional consequences of their replacement. Biochemistry. 1992 Apr 28; 31(16):4053-7.
Steczko J, Donoho GP, Clemens JC, Dixon JE, Axelrod B. PMID: 1567851.
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PubMed Mentions:
25 Fields:
Translation:
AnimalsCells
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Avian glutamine phosphoribosylpyrophosphate amidotransferase propeptide processing and activity are dependent upon essential cysteine residues. J Biol Chem. 1992 Apr 15; 267(11):7936-42.
Zhou G, Broyles SS, Dixon JE, Zalkin H. PMID: 1560022.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Expression of a protein tyrosine phosphatase in normal and v-src-transformed mouse 3T3 fibroblasts. J Cell Biol. 1992 Apr; 117(2):401-14.
Woodford-Thomas TA, Rhodes JD, Dixon JE. PMID: 1373143; PMCID: PMC2289417.
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PubMed Mentions:
55 Fields:
Translation:
AnimalsCells
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A mutation in adenylosuccinate lyase associated with mental retardation and autistic features. Nat Genet. 1992 Apr; 1(1):59-63.
Stone RL, Aimi J, Barshop BA, Jaeken J, Van den Berghe G, Zalkin H, Dixon JE. PMID: 1302001.
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PubMed Mentions:
31 Fields:
Translation:
HumansCells
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Active site labeling of a receptor-like protein tyrosine phosphatase. J Biol Chem. 1992 Jan 05; 267(1):140-3.
Pot DA, Dixon JE. PMID: 1730581.
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PubMed Mentions:
17 Fields:
Translation:
AnimalsCells
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Isolation of two complementary deoxyribonucleic acid clones from a rat insulinoma cell line based on similarities to Kex2 and furin sequences and the specific localization of each transcript to endocrine and neuroendocrine tissues in rats. Endocrinology. 1991 Dec; 129(6):3053-63.
Hakes DJ, Birch NP, Mezey A, Dixon JE. PMID: 1954888.
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PubMed Mentions:
13 Fields:
Translation:
AnimalsCells
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Involvement of lysine residues 289 and 291 of the cAMP-responsive element-binding protein in the recognition of the cAMP-responsive element. J Biol Chem. 1991 Nov 15; 266(32):21444-50.
Andrisani OM, Dixon JE. PMID: 1834659.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Microbial pathogenesis and tyrosine dephosphorylation: surprising 'bedfellows'. Mol Microbiol. 1991 Nov; 5(11):2617-20.
Clemens JC, Guan K, Bliska JB, Falkow S, Dixon JE. PMID: 1723471.
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PubMed Mentions:
2 Fields:
Translation:
HumansCells
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Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase. J Biol Chem. 1991 Oct 15; 266(29):19688-96.
Pot DA, Woodford TA, Remboutsika E, Haun RS, Dixon JE. PMID: 1918076.
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PubMed Mentions:
31 Fields:
Translation:
AnimalsCells
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De novo purine nucleotide biosynthesis: cloning, sequencing and expression of a chicken PurH cDNA encoding 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase-IMP cyclohydrolase. Gene. 1991 Oct 15; 106(2):197-205.
Ni L, Guan K, Zalkin H, Dixon JE. PMID: 1937050.
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PubMed Mentions:
8 Fields:
Translation:
AnimalsCells
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Evidence for protein-tyrosine-phosphatase catalysis proceeding via a cysteine-phosphate intermediate. J Biol Chem. 1991 Sep 15; 266(26):17026-30.
Guan KL, Dixon JE. PMID: 1654322.
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PubMed Mentions:
114 Fields:
Translation:
AnimalsCells
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Structural characterization of the rat carboxypeptidase-E gene. Mol Endocrinol. 1991 Sep; 5(9):1257-68.
Jung YK, Kunczt CJ, Pearson RK, Dixon JE, Fricker LD. PMID: 1770952.
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PubMed Mentions:
7 Fields:
Translation:
AnimalsCells
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Characterization of the carboxyl-terminal sequences responsible for protein retention in the endoplasmic reticulum. J Biol Chem. 1991 Aug 05; 266(22):14277-82.
Andres DA, Rhodes JD, Meisel RL, Dixon JE. PMID: 1650354.
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PubMed Mentions:
19 Fields:
Translation:
Cells
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Cloning and expression of a yeast protein tyrosine phosphatase. J Biol Chem. 1991 Jul 15; 266(20):12964-70.
Guan KL, Deschenes RJ, Qiu H, Dixon JE. PMID: 1649172.
View in:
PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Effect of ethanol and low-temperature culture on expression of soybean lipoxygenase L-1 in Escherichia coli. Protein Expr Purif. 1991 Apr-Jun; 2(2-3):221-7.
Steczko J, Donoho GA, Dixon JE, Sugimoto T, Axelrod B. PMID: 1821792.
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PubMed Mentions:
14 Fields:
Translation:
AnimalsCells
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A Tyr/Ser protein phosphatase encoded by vaccinia virus. Nature. 1991 Mar 28; 350(6316):359-62.
Guan KL, Broyles SS, Dixon JE. PMID: 1848923.
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PubMed Mentions:
119 Fields:
Translation:
HumansAnimalsCells
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Tyrosine phosphate hydrolysis of host proteins by an essential Yersinia virulence determinant. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1187-91.
Bliska JB, Guan KL, Dixon JE, Falkow S. PMID: 1705028; PMCID: PMC50982.
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PubMed Mentions:
149 Fields:
Translation:
AnimalsCells
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Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal Biochem. 1991 Feb 01; 192(2):262-7.
Guan KL, Dixon JE. PMID: 1852137.
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PubMed Mentions:
640 Fields:
Translation:
AnimalsCells
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Cloning and expression of avian glutamine phosphoribosylpyrophosphate amidotransferase. Conservation of a bacterial propeptide sequence supports a role for posttranslational processing. J Biol Chem. 1990 Dec 05; 265(34):21152-9.
Zhou GC, Dixon JE, Zalkin H. PMID: 2123487.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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De novo purine nucleotide biosynthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementation in E. coli. Nucleic Acids Res. 1990 Nov 25; 18(22):6665-72.
Aimi J, Qiu H, Williams J, Zalkin H, Dixon JE. PMID: 2147474; PMCID: PMC332626.
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PubMed Mentions:
24 Fields:
Translation:
HumansAnimalsCells
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A transcriptional enhancer essential for the expression of the rat cholecystokinin gene contains a sequence identical to the -296 element of the human c-fos gene. J Biol Chem. 1990 Sep 15; 265(26):15455-63.
Haun RS, Dixon JE. PMID: 2118525.
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PubMed Mentions:
2 Fields:
Translation:
HumansAnimalsCells
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Efforts directed at understanding cell-specific somatostatin gene expression. Metabolism. 1990 Sep; 39(9 Suppl 2):17-9.
Dixon JE, Zhu A, Andrisani O. PMID: 1976211.
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PubMed Mentions:
1 Fields:
Translation:
HumansAnimalsCells
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Protein tyrosine phosphatase activity of an essential virulence determinant in Yersinia. Science. 1990 Aug 03; 249(4968):553-6.
Guan KL, Dixon JE. PMID: 2166336.
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PubMed Mentions:
165 Fields:
Translation:
Cells
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Cloning of a cDNA encoding adenylosuccinate lyase by functional complementation in Escherichia coli. J Biol Chem. 1990 Jun 05; 265(16):9011-4.
Aimi J, Badylak J, Williams J, Chen ZD, Zalkin H, Dixon JE. PMID: 2111814.
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PubMed Mentions:
9 Fields:
Translation:
HumansAnimalsCells
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Variants of the carboxyl-terminal KDEL sequence direct intracellular retention. J Biol Chem. 1990 Apr 15; 265(11):5952-5.
Andres DA, Dickerson IM, Dixon JE. PMID: 2318841.
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PubMed Mentions:
28 Fields:
Translation:
AnimalsCells
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Cloning of a chicken liver cDNA encoding 5-aminoimidazole ribonucleotide carboxylase and 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase by functional complementation of Escherichia coli pur mutants. Proc Natl Acad Sci U S A. 1990 Apr; 87(8):3097-101.
Chen ZD, Dixon JE, Zalkin H. PMID: 1691501; PMCID: PMC53841.
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PubMed Mentions:
10 Fields:
Translation:
AnimalsCells
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Cloning and structural characterization of porcine heart aconitase. J Biol Chem. 1990 Feb 15; 265(5):2814-21.
Zheng L, Andrews PC, Hermodson MA, Dixon JE, Zalkin H. PMID: 2303429.
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PubMed Mentions:
23 Fields:
Translation:
AnimalsCells
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Biosynthesis and posttranslational processing of site-directed endoproteolytic cleavage mutants of pro-neuropeptide Y in mouse pituitary cells. J Biol Chem. 1990 Feb 15; 265(5):2462-9.
Dickerson IM, Dixon JE, Mains RE. PMID: 2303410.
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PubMed Mentions:
7 Fields:
Translation:
HumansAnimalsCells
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Cloning and expression of a protein-tyrosine-phosphatase. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1501-5.
Guan KL, Haun RS, Watson SJ, Geahlen RL, Dixon JE. PMID: 2154749; PMCID: PMC53503.
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PubMed Mentions:
63 Fields:
Translation:
AnimalsCells
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Cellular contacts required for neural induction in Xenopus embryos: evidence for two signals. Development. 1989 Aug; 106(4):749-57.
Dixon JE, Kintner CR. PMID: 2485245.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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Rat preprocarboxypeptidase H. Cloning, characterization, and sequence of the cDNA and regulation of the mRNA by corticotropin-releasing factor. J Biol Chem. 1989 Apr 05; 264(10):5988-95.
Rodríguez C, Brayton KA, Brownstein M, Dixon JE. PMID: 2784437.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells
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Assaying the reporter gene chloramphenicol acetyltransferase. Methods Enzymol. 1989; 168:690-701.
Crabb DW, Minth CD, Dixon JE. PMID: 2725317.
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PubMed Mentions:
4 Fields:
Translation:
HumansAnimalsCells
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Application of fast atom bombardment mass spectrometry to posttranslational modifications of neuropeptides. Methods Enzymol. 1989; 168:72-103.
Andrews PC, Dixon JE. PMID: 2566895.
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AnimalsCells
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Secretion of atrial natriuretic factor-(1-98) by primary cardiac myocytes. J Biol Chem. 1988 Nov 05; 263(31):16073-81.
Glembotski CC, Dixon JE, Gibson TR. PMID: 2972704.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Rapid identification of clones using the same degenerate oligonucleotide mixture for both screening and sequencing. Anal Biochem. 1988 Apr; 170(1):110-5.
Nichols R, Dixon JE. PMID: 3389502.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Post-translational processing of preprosomatostatin-II examined using fast atom bombardment mass spectrometry. J Biol Chem. 1987 Sep 15; 262(26):12692-9.
Andrews PC, Nichols R, Dixon JE. PMID: 2887572.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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Isolation of products and intermediates of pancreatic prosomatostatin processing: use of fast atom bombardment mass spectrometry as an aid in analysis of prohormone processing. Biochemistry. 1987 Jul 28; 26(15):4853-61.
Andrews PC, Dixon JE. PMID: 2889466.
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PubMed Mentions: Fields:
Translation:
AnimalsCells
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A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells. Anal Biochem. 1987 May 15; 163(1):88-92.
Crabb DW, Dixon JE. PMID: 3475989.
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PubMed Mentions:
39 Fields:
Translation:
HumansAnimalsCells
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A procedure for in situ alkylation of cystine residues on glass fiber prior to protein microsequence analysis. Anal Biochem. 1987 Mar; 161(2):524-8.
Andrews PC, Dixon JE. PMID: 2883913.
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PubMed Mentions:
28 Fields:
Translation:
Cells
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Cotranslational and posttranslational proteolytic processing of preprosomatostatin-I in intact islet tissue. J Cell Biol. 1986 Oct; 103(4):1205-11.
Noe BD, Andrews PC, Dixon JE, Spiess J. PMID: 2876999; PMCID: PMC2114339.
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PubMed Mentions:
2 Fields:
Translation:
AnimalsCells
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A new approach for detection and assignment of disulfide bonds in peptides. Anal Biochem. 1986 Mar; 153(2):348-53.
Yazdanparast R, Andrews P, Smith DL, Dixon JE. PMID: 3706715.
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PubMed Mentions:
7 Fields:
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Primary structural comparison of the preprohormones cholecystokinin and gastrin. FEBS Lett. 1985 Mar 11; 182(1):135-8.
Deschenes RJ, Narayana SV, Argos P, Dixon JE. PMID: 3972119.
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PubMed Mentions:
3 Fields:
Translation:
AnimalsCells
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Somatostatins of the channel catfish. Adv Exp Med Biol. 1985; 188:19-29.
Dixon JE, Andrews PC. PMID: 2863931.
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AnimalsCells
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Thiol: protein disulfide exchange enzymes. Methods Enzymol. 1985; 113:541-7.
Morin JE, Dixon JE. PMID: 4088073.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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Rat pituitary N alpha-acetyltransferase. Methods Enzymol. 1984; 106:170-9.
Dixon JE, Woodford TA. PMID: 6092829.
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PubMed Mentions:
1 Fields:
Translation:
AnimalsCells
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Characterization of proline endopeptidase from rat brain. Biochemistry. 1980 Nov 25; 19(24):5494-500.
Andrews PC, Hines CM, Dixon JE. PMID: 6779865.
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PubMed Mentions:
4 Fields:
Translation:
AnimalsCells
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New fluorogenic substrates for a rat brain proline endopeptidase. Anal Biochem. 1980 Jun; 105(1):58-64.
Taylor WL, Andrews PC, Henrikson CK, Dixon JE. PMID: 7004269.
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PubMed Mentions:
2 Fields:
Translation:
Animals
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The Nalpha-acetylation of corticotropin and fragments of corticotropin by a rat pituitary Nalpha-acetyltransferase. J Biol Chem. 1979 Jun 25; 254(12):4993-9.
Woodford TA, Dixon JE. PMID: 221456.
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PubMed Mentions:
5 Fields:
Translation:
AnimalsCells
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A possible role for glass bead immobilized enzymes as therapeutic agents (immobilized uricase as enzyme therapy for hyperuricemia). Biochem Med. 1975 Jan; 12(1):79-91.
Venter JC, Venter BR, Dixon JE, Kaplan NO. PMID: 806289.
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AnimalsCells
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Purification and separation of pyridine nucleotide-linked dehydrogenases by affinity chromatography techniques. Proc Natl Acad Sci U S A. 1974 Sep; 71(9):3450-4.
Kaplan NO, Everse J, Dixon JE, Stolzenbach FE, Lee CY, Lee CL, Taylor SS, Mosbach K. PMID: 4372619; PMCID: PMC433791.
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PubMed Mentions:
5 Fields:
Translation:
HumansAnimals
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Production of glass bead-immobilized catecholamines. Methods Enzymol. 1974; 38:180-6.
Venter JC, Dixon JE. PMID: 4453191.
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PubMed Mentions: Fields:
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Comparison of the rate constants for general base catalyzed prototropy and racemization of the aldimine species formed from 3-hydroxypyridine-4-carboxaldehyde and alanine. Biochemistry. 1973 Nov 06; 12(23):4762-6.
Dixon JE, Bruice TC. PMID: 4773854.
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PubMed Mentions:
10 Fields:
Translation:
Cells
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An apparatus for the determination of kinetic parameters associated with immobilized enzymes. Anal Biochem. 1973 Sep; 55(1):282-7.
Widmer F, Dixon JE, Kaplan NO. PMID: 4753153.
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Animals
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Immobilized catecholamine and cocaine effects on contractility of cardiac muscle. Proc Natl Acad Sci U S A. 1973 Apr; 70(4):1214-7.
Venter JC, Ross J, Dixon JE, Mayer SE, Kaplan NO. PMID: 4515619; PMCID: PMC433460.
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7 Fields:
Translation:
Animals
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Biologically active catecholamines covalentyly bound to glass beads. Proc Natl Acad Sci U S A. 1972 May; 69(5):1141-5.
Venter JC, Dixon JE, Maroko PR, Kaplan NO. PMID: 4338583; PMCID: PMC426649.
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PubMed Mentions:
11 Fields:
Translation:
AnimalsCells