April Lukowski

Title(s)	Assistant Professor, Scripps Institution of Oceanography Department
School	Vc-marine Sciences
Address	9500 Gilman Drive # La Jolla CA 92093
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Research

Research Activities and Funding

Interrogating novel biosynthetic sources for the production of polybrominated diphenyl ethers
NIH F32ES033540Sep 1, 2021 - Aug 31, 2024
Role: Principal Investigator

Biocatalytic approaches to antiepileptic drug targets
NIH F31NS111906May 1, 2019 - Jan 31, 2022
Role: Principal Investigator

Bibliographic

Publications

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.

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Enzymatic Halogenation of Terminal Alkynes. J Am Chem Soc. 2023 08 30; 145(34):18716-18721. Lukowski AL, Hubert FM, Ngo TE, Avalon NE, Gerwick WH, Moore BS. PMID: 37594919; PMCID: PMC10486310.

View in: PubMed Mentions: 1 Fields:
Che Chemistry
Translation:Cells
Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme. bioRxiv. 2023 Aug 03. Adak S, Ye N, Calderone LA, Schäfer RJB, Lukowski AL, Pandelia ME, Drennan CL, Moore BS. PMID: 37577561; PMCID: PMC10418191.

View in: PubMed Mentions:
Biocatalytic oxidative cross-coupling reactions for biaryl bond formation. Nature. 2022 03; 603(7899):79-85. Zetzsche LE, Yazarians JA, Chakrabarty S, Hinze ME, Murray LAM, Lukowski AL, Joyce LA, Narayan ARH. PMID: 35236972; PMCID: PMC9213091.

View in: PubMed Mentions: 16 Fields:
Sci Science
Translation:Cells
From Tryptophan to Toxin: Nature's Convergent Biosynthetic Strategy to Aetokthonotoxin. J Am Chem Soc. 2022 02 23; 144(7):2861-2866. Adak S, Lukowski AL, Schäfer RJB, Moore BS. PMID: 35142504; PMCID: PMC9004672.

View in: PubMed Mentions: 12 Fields:
Che Chemistry
Translation:Cells
Harnessing ortho-Quinone Methides in Natural Product Biosynthesis and Biocatalysis. J Nat Prod. 2022 03 25; 85(3):688-701. Purdy TN, Moore BS, Lukowski AL. PMID: 35108487; PMCID: PMC9006567.

View in: PubMed Mentions: 1 Fields:
Pha Pharmacology
Translation:Cells
Design principles for site-selective hydroxylation by a Rieske oxygenase. Nat Commun. 2022 01 11; 13(1):255. Liu J, Tian J, Perry C, Lukowski AL, Doukov TI, Narayan ARH, Bridwell-Rabb J. PMID: 35017498; PMCID: PMC8752792.

View in: PubMed Mentions: 6 Fields:
Bio Biology Sci Science
Translation:Cells
Structural basis for divergent C-H hydroxylation selectivity in two Rieske oxygenases. Nat Commun. 2020 06 12; 11(1):2991. Lukowski AL, Liu J, Bridwell-Rabb J, Narayan ARH. PMID: 32532989; PMCID: PMC7293229.

View in: PubMed Mentions: 17 Fields:
Bio Biology Sci Science
Translation:Cells
The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Nav1.1 in addition to Nav1.6. Neurosci Lett. 2020 04 17; 724:134853. Denomme N, Lukowski AL, Hull JM, Jameson MB, Bouza AA, Narayan ARH, Isom LL. PMID: 32114117; PMCID: PMC7096269.

View in: PubMed Mentions: 7 Fields:
Neu Neurology
Translation:Humans Animals Cells
Substrate Promiscuity of a Paralytic Shellfish Toxin Amidinotransferase. ACS Chem Biol. 2020 03 20; 15(3):626-631. Lukowski AL, Mallik L, Hinze ME, Carlson BM, Ellinwood DC, Pyser JB, Koutmos M, Narayan ARH. PMID: 32058687; PMCID: PMC7362304.

View in: PubMed Mentions: 8 Fields:
Bio Biochemistry Bio Biology
Translation:Cells
Biocatalytic Detoxification of Paralytic Shellfish Toxins. ACS Chem Biol. 2019 05 17; 14(5):941-948. Lukowski AL, Denomme N, Hinze ME, Hall S, Isom LL, Narayan ARH. PMID: 30983320; PMCID: PMC6528162.

View in: PubMed Mentions: 15 Fields:
Bio Biochemistry Bio Biology
Translation:Animals Cells
Natural Voltage-Gated Sodium Channel Ligands: Biosynthesis and Biology. Chembiochem. 2019 05 15; 20(10):1231-1241. Lukowski AL, Narayan ARH. PMID: 30605564; PMCID: PMC6579537.

View in: PubMed Mentions: 3 Fields:
Bio Biochemistry
Translation:Animals Cells
Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization. ACS Catal. 2019 Apr 05; 9(4):3633-3640. Benítez AR, Tweedy S, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL, Palfey BA, Smith JL, Narayan ARH. PMID: 31346489; PMCID: PMC6658140.

View in: PubMed Mentions: 14
C-H Hydroxylation in Paralytic Shellfish Toxin Biosynthesis. J Am Chem Soc. 2018 09 19; 140(37):11863-11869. Lukowski AL, Ellinwood DC, Hinze ME, DeLuca RJ, Du Bois J, Hall S, Narayan ARH. PMID: 30192526; PMCID: PMC6558983.

View in: PubMed Mentions: 26 Fields:
Che Chemistry
Translation:Animals Cells
Biocatalytic site- and enantioselective oxidative dearomatization of phenols. Nat Chem. 2018 02; 10(2):119-125. Baker Dockrey SA, Lukowski AL, Becker MR, Narayan ARH. PMID: 29359749; PMCID: PMC6503525.

View in: PubMed Mentions: 39 Fields:
Che Chemistry
Translation:Cells