April Lukowski

Title(s)Assistant Professor, Scripps Institution of Oceanography Department
SchoolVc-marine Sciences
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Interrogating novel biosynthetic sources for the production of polybrominated diphenyl ethers
    NIH F32ES033540Sep 1, 2021 - Aug 31, 2024
    Role: Principal Investigator
    Biocatalytic approaches to antiepileptic drug targets
    NIH F31NS111906May 1, 2019 - Jan 31, 2022
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Enzymatic Halogenation of Terminal Alkynes. J Am Chem Soc. 2023 08 30; 145(34):18716-18721. Lukowski AL, Hubert FM, Ngo TE, Avalon NE, Gerwick WH, Moore BS. PMID: 37594919; PMCID: PMC10486310.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    2. Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme. bioRxiv. 2023 Aug 03. Adak S, Ye N, Calderone LA, Schäfer RJB, Lukowski AL, Pandelia ME, Drennan CL, Moore BS. PMID: 37577561; PMCID: PMC10418191.
      View in: PubMed   Mentions:
    3. Biocatalytic oxidative cross-coupling reactions for biaryl bond formation. Nature. 2022 03; 603(7899):79-85. Zetzsche LE, Yazarians JA, Chakrabarty S, Hinze ME, Murray LAM, Lukowski AL, Joyce LA, Narayan ARH. PMID: 35236972; PMCID: PMC9213091.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    4. From Tryptophan to Toxin: Nature's Convergent Biosynthetic Strategy to Aetokthonotoxin. J Am Chem Soc. 2022 02 23; 144(7):2861-2866. Adak S, Lukowski AL, Schäfer RJB, Moore BS. PMID: 35142504; PMCID: PMC9004672.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    5. Harnessing ortho-Quinone Methides in Natural Product Biosynthesis and Biocatalysis. J Nat Prod. 2022 03 25; 85(3):688-701. Purdy TN, Moore BS, Lukowski AL. PMID: 35108487; PMCID: PMC9006567.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    6. Design principles for site-selective hydroxylation by a Rieske oxygenase. Nat Commun. 2022 01 11; 13(1):255. Liu J, Tian J, Perry C, Lukowski AL, Doukov TI, Narayan ARH, Bridwell-Rabb J. PMID: 35017498; PMCID: PMC8752792.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    7. Structural basis for divergent C-H hydroxylation selectivity in two Rieske oxygenases. Nat Commun. 2020 06 12; 11(1):2991. Lukowski AL, Liu J, Bridwell-Rabb J, Narayan ARH. PMID: 32532989; PMCID: PMC7293229.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    8. The voltage-gated sodium channel inhibitor, 4,9-anhydrotetrodotoxin, blocks human Nav1.1 in addition to Nav1.6. Neurosci Lett. 2020 04 17; 724:134853. Denomme N, Lukowski AL, Hull JM, Jameson MB, Bouza AA, Narayan ARH, Isom LL. PMID: 32114117; PMCID: PMC7096269.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    9. Substrate Promiscuity of a Paralytic Shellfish Toxin Amidinotransferase. ACS Chem Biol. 2020 03 20; 15(3):626-631. Lukowski AL, Mallik L, Hinze ME, Carlson BM, Ellinwood DC, Pyser JB, Koutmos M, Narayan ARH. PMID: 32058687; PMCID: PMC7362304.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    10. Biocatalytic Detoxification of Paralytic Shellfish Toxins. ACS Chem Biol. 2019 05 17; 14(5):941-948. Lukowski AL, Denomme N, Hinze ME, Hall S, Isom LL, Narayan ARH. PMID: 30983320; PMCID: PMC6528162.
      View in: PubMed   Mentions: 15     Fields:    Translation:AnimalsCells
    11. Natural Voltage-Gated Sodium Channel Ligands: Biosynthesis and Biology. Chembiochem. 2019 05 15; 20(10):1231-1241. Lukowski AL, Narayan ARH. PMID: 30605564; PMCID: PMC6579537.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    12. Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization. ACS Catal. 2019 Apr 05; 9(4):3633-3640. Benítez AR, Tweedy S, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL, Palfey BA, Smith JL, Narayan ARH. PMID: 31346489; PMCID: PMC6658140.
      View in: PubMed   Mentions: 14  
    13. C-H Hydroxylation in Paralytic Shellfish Toxin Biosynthesis. J Am Chem Soc. 2018 09 19; 140(37):11863-11869. Lukowski AL, Ellinwood DC, Hinze ME, DeLuca RJ, Du Bois J, Hall S, Narayan ARH. PMID: 30192526; PMCID: PMC6558983.
      View in: PubMed   Mentions: 26     Fields:    Translation:AnimalsCells
    14. Biocatalytic site- and enantioselective oxidative dearomatization of phenols. Nat Chem. 2018 02; 10(2):119-125. Baker Dockrey SA, Lukowski AL, Becker MR, Narayan ARH. PMID: 29359749; PMCID: PMC6503525.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
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