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Victoria Risbrough

TitleProfessor In Residence
InstitutionUniversity of California San Diego
DepartmentPsychiatry
Address9500 Gilman Drive #0804
La Jolla CA 92093
Phone619-543-2900
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    Biography

    Dr. Risbrough received her B.A. degree in Psychology and her Ph.D. in Neuroscience from the University of California, San Diego. She joined as faculty in the Department of Psychiatry at UCSD in 2007 and became Associate Professor in 2012. She is the Associate Director of Neuroscience for the Center of Excellence for Stress and Mental Health at the San Diego Veterans Healthcare System. Dr. Risbrough is the Principal Investigator on awards from the National Institute of Mental Health, NARSAD, Veteran’s Affairs and the U.S. Department of Defense. She is also Director of the Neurocognition Project for the Marine Resiliency Study funded by Navy BUMED. She was the Guest Editor for the Special Issue on PTSD for Neuropharmacology and is an Associate Editor for a number of pharmacology journals. She is also a member of the Molecular Neuropharmacology and Signaling study section for NIH. Dr. Risbrough’s research is centered on translational mechanisms and treatments of anxiety disorders using preclinical and clinical approaches. Her primary focus is to identify mechanisms of risk and resilience to anxiety disorders, particularly posttraumatic stress disorder as well as development of new pharmacological treatments for these disorders. For example, she examines the contribution of corticotropin releasing factor to stress and anxiety responses using pharmacological and genetic techniques in mice. Her program also identifies genetic and environmental contributions to stress behavior and fear learning. For example she has recently been funded to examine the role of the COMTVal158Met polymorphism in PTSD risk and treatment response. By measuring physiological responses to stress (including heart rate and startle reactivity) in animal models and in clinic, her research develops translational probes of anxiety responding and treatment efficacy.

    Research Interests

    Dr. Risbrough’s research is centered on translational mechanisms and treatments of anxiety disorders using preclinical and clinical approaches. Her primary focus is understanding mechanisms of risk and resilience to anxiety disorders, particularly post-traumatic stress disorder. For example, she examines the contribution of corticotropin releasing factor to stress and anxiety responses using pharmacological and genetic techniques in mice. Her program also identifies genetic and environmental contributions to stress behavior and fear learning. By measuring physiological responses to stress (including heart rate and startle reactivity) in animal models and in clinic, her research develops translational probes of anxiety responding and treatment efficacy.

    Clinical Focus

    The goal of our work is to understand the basic mechanisms underlying anxiety and fear responses, as well as to identify biological factors contributing to the risk of and resilience to development of anxiety disorders. With this information we hope to develop better measures of treatment response in anxiety disorders and identify novel targets of pharmacotherapeutics.


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    Collapse Research Activities and Funding
    Developing rodent models of PTSD/AUD: leveraging clinic-based strategies
    NIH/NIAAA R01AA026560Sep 12, 2017 - Aug 31, 2022
    Role: Principal Investigator
    Role of COMTval158met in PTSD risk and treatment response
    VA I01BX002558Oct 1, 2014 - Sep 30, 2018
    Role: Principal Investigator
    Understanding the Role of COMT Variants in Sensorimotor Gating
    NIH/NIMH R33MH083499May 15, 2008 - Apr 30, 2012
    Role: Principal Investigator
    Understanding the Role of COMT Variants in Sensorimotor Gating
    NIH/NIMH R21MH083499May 15, 2008 - Apr 30, 2010
    Role: Principal Investigator
    Murine model of CRF effects on fear extinction: relevance to PTSD
    NIH/NIMH R21MH076850May 5, 2006 - Apr 30, 2009
    Role: Principal Investigator
    Stress and CRF System Effects on Information Processing
    NIH/NIMH R01MH074697Jul 1, 2005 - Apr 30, 2015
    Role: Principal Investigator
    Role of CRF and 5-HT1A receptors in ASR
    NIH/NIMH F31MH068133Apr 1, 2003 - Mar 31, 2005
    Role: Principal Investigator

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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Straus LD, Norman SB, Risbrough VB, Acheson DT, Drummond SPA. REM sleep and safety signal learning in posttraumatic stress disorder: A preliminary study in military veterans. Neurobiol Stress. 2018 Nov; 9:22-28. PMID: 30116769.
      View in: PubMed
    2. Risbrough VB, Glynn LM, Davis EP, Sandman CA, Obenaus A, Stern HS, Keator DB, Yassa MA, Baram TZ, Baker DG. Does Anhedonia Presage Increased Risk of Posttraumatic Stress Disorder? : Adolescent Anhedonia and Posttraumatic Disorders. Curr Top Behav Neurosci. 2018 May 24. PMID: 29796839.
      View in: PubMed
    3. Huang MX, Nichols S, Robb-Swan A, Angeles-Quinto A, Harrington DL, Drake A, Huang CW, Song T, Diwakar M, Risbrough VB, Matthews S, Clifford R, Cheng CK, Huang JW, Sinha A, Yurgil KA, Ji Z, Lerman I, Lee RR, Baker DG. MEG Working Memory N-Back Task Reveals Functional Deficits in Combat-Related Mild Traumatic Brain Injury. Cereb Cortex. 2018 Apr 13. PMID: 29668852.
      View in: PubMed
    4. Stout DM, Glenn DE, Acheson DT, Spadoni AD, Risbrough VB, Simmons AN. Neural measures associated with configural threat acquisition. Neurobiol Learn Mem. 2018 Apr; 150:99-106. PMID: 29544725.
      View in: PubMed
    5. Higgins DM, Martin AM, Baker DG, Vasterling JJ, Risbrough V. The Relationship Between Chronic Pain and Neurocognitive Function: A Systematic Review. Clin J Pain. 2018 Mar; 34(3):262-275. PMID: 28719507.
      View in: PubMed
    6. Thomas ML, Brown GG, Gur RC, Moore TM, Patt VM, Risbrough VB, Baker DG. A signal detection-item response theory model for evaluating neuropsychological measures. J Clin Exp Neuropsychol. 2018 Feb 05; 1-16. PMID: 29402152.
      View in: PubMed
    7. Stout DM, Acheson DT, Moore TM, Gur RC, Baker DG, Geyer MA, Risbrough VB. Individual variation in working memory is associated with fear extinction performance. Behav Res Ther. 2018 Mar; 102:52-59. PMID: 29331727.
      View in: PubMed
    8. Wolf EJ, Maniates H, Nugent N, Maihofer AX, Armstrong D, Ratanatharathorn A, Ashley-Koch AE, Garrett M, Kimbrel NA, Lori A, Aiello AE, Baker DG, Beckham JC, Boks MP, Galea S, Geuze E, Hauser MA, Kessler RC, Koenen KC, Miller MW, Ressler KJ, Risbrough V, Rutten BPF, Stein MB, Ursano RJ, Vermetten E, Vinkers CH, Uddin M, Smith AK, Nievergelt CM, Logue MW. Traumatic stress and accelerated DNA methylation age: A meta-analysis. Psychoneuroendocrinology. 2018 Jun; 92:123-134. PMID: 29452766.
      View in: PubMed
    9. Deslauriers J, Toth M, Der-Avakian A, Risbrough VB. Current Status of Animal Models of Posttraumatic Stress Disorder: Behavioral and Biological Phenotypes, and Future Challenges in Improving Translation. Biol Psychiatry. 2018 May 15; 83(10):895-907. PMID: 29338843.
      View in: PubMed
    10. Glenn DE, Risbrough VB, Simmons AN, Acheson DT, Stout DM. The Future of Contextual Fear Learning for PTSD Research: A Methodological Review of Neuroimaging Studies. Curr Top Behav Neurosci. 2017 Oct 21. PMID: 29063483.
      View in: PubMed
    11. Straus LD, Drummond SPA, Risbrough VB, Norman SB. Sleep Disruption, Safety Learning, and Fear Extinction in Humans: Implications for Posttraumatic Stress Disorder. Curr Top Behav Neurosci. 2017 Sep 24. PMID: 28942597.
      View in: PubMed
    12. Breen MS, Tylee DS, Maihofer AX, Neylan TC, Mehta D, Binder EB, Chandler SD, Hess JL, Kremen WS, Risbrough VB, Woelk CH, Baker DG, Nievergelt CM, Tsuang MT, Buxbaum JD, Glatt SJ. PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma. Neuropsychopharmacology. 2018 Feb; 43(3):469-481. PMID: 28925389.
      View in: PubMed
    13. Moore TM, Risbrough VB, Baker DG, Larson GE, Glenn DE, Nievergelt CM, Maihofer A, Port AM, Jackson CT, Ruparel K, Gur RC. Effects of military service and deployment on clinical symptomatology: The role of trauma exposure and social support. J Psychiatr Res. 2017 Dec; 95:121-128. PMID: 28843074.
      View in: PubMed
    14. Deslauriers J, Acheson DT, Maihofer AX, Nievergelt CM, Baker DG, Geyer MA, Risbrough VB. COMT val158met polymorphism links to altered fear conditioning and extinction are modulated by PTSD and childhood trauma. Depress Anxiety. 2018 Jan; 35(1):32-42. PMID: 28833952.
      View in: PubMed
    15. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 Aug 02; 8:16140. PMID: 28767105.
      View in: PubMed
    16. Nolte IM, Munoz ML, Tragante V, Amare AT, Jansen R, Vaez A, von der Heyde B, Avery CL, Bis JC, Dierckx B, van Dongen J, Gogarten SM, Goyette P, Hernesniemi J, Huikari V, Hwang SJ, Jaju D, Kerr KF, Kluttig A, Krijthe BP, Kumar J, van der Laan SW, Lyytikäinen LP, Maihofer AX, Minassian A, van der Most PJ, Müller-Nurasyid M, Nivard M, Salvi E, Stewart JD, Thayer JF, Verweij N, Wong A, Zabaneh D, Zafarmand MH, Abdellaoui A, Albarwani S, Albert C, Alonso A, Ashar F, Auvinen J, Axelsson T, Baker DG, de Bakker PIW, Barcella M, Bayoumi R, Bieringa RJ, Boomsma D, Boucher G, Britton AR, Christophersen I, Dietrich A, Ehret GB, Ellinor PT, Eskola M, Felix JF, Floras JS, Franco OH, Friberg P, Gademan MGJ, Geyer MA, Giedraitis V, Hartman CA, Hemerich D, Hofman A, Hottenga JJ, Huikuri H, Hutri-Kähönen N, Jouven X, Junttila J, Juonala M, Kiviniemi AM, Kors JA, Kumari M, Kuznetsova T, Laurie CC, Lefrandt JD, Li Y, Li Y, Liao D, Limacher MC, Lin HJ, Lindgren CM, Lubitz SA, Mahajan A, McKnight B, Zu Schwabedissen HM, Milaneschi Y, Mononen N, Morris AP, Nalls MA, Navis G, Neijts M, Nikus K, North KE, O'Connor DT, Ormel J, Perz S, Peters A, Psaty BM, Raitakari OT, Risbrough VB, Sinner MF, Siscovick D, Smit JH, Smith NL, Soliman EZ, Sotoodehnia N, Staessen JA, Stein PK, Stilp AM, Stolarz-Skrzypek K, Strauch K, Sundström J, Swenne CA, Syvänen AC, Tardif JC, Taylor KD, Teumer A, Thornton TA, Tinker LE, Uitterlinden AG, van Setten J, Voss A, Waldenberger M, Wilhelmsen KC, Willemsen G, Wong Q, Zhang ZM, Zonderman AB, Cusi D, Evans MK, Greiser HK, van der Harst P, Hassan M, Ingelsson E, Järvelin MR, Kääb S, Kähönen M, Kivimaki M, Kooperberg C, Kuh D, Lehtimäki T, Lind L, Nievergelt CM, O'Donnell CJ, Oldehinkel AJ, Penninx B, Reiner AP, Riese H, van Roon AM, Rioux JD, Rotter JI, Sofer T, Stricker BH, Tiemeier H, Vrijkotte TGM, Asselbergs FW, Brundel BJJM, Heckbert SR, Whitsel EA, den Hoed M, Snieder H, de Geus EJC. Genetic loci associated with heart rate variability and their effects on cardiac disease risk. Nat Commun. 2017 Jun 14; 8:15805. PMID: 28613276.
      View in: PubMed
    17. Glenn DE, Acheson DT, Geyer MA, Nievergelt CM, Baker DG, Risbrough VB. Fear learning alterations after traumatic brain injury and their role in development of posttraumatic stress symptoms. Depress Anxiety. 2017 08; 34(8):723-733. PMID: 28489272.
      View in: PubMed
    18. Deslauriers J, Powell S, Risbrough VB. Immune signaling mechanisms of PTSD risk and symptom development: insights from animal models. Curr Opin Behav Sci. 2017 Apr; 14:123-132. PMID: 28758144.
      View in: PubMed
    19. Straus LD, Acheson DT, Risbrough VB, Drummond SPA. Sleep Deprivation Disrupts Recall of Conditioned Fear Extinction. Biol Psychiatry Cogn Neurosci Neuroimaging. 2017 Mar; 2(2):123-129. PMID: 28758152.
      View in: PubMed
    20. Deslauriers J, van Wijngaarde M, Geyer MA, Powell S, Risbrough VB. Effects of LPS-induced immune activation prior to trauma exposure on PTSD-like symptoms in mice. Behav Brain Res. 2017 04 14; 323:117-123. PMID: 28159589.
      View in: PubMed
    21. Huang MX, Harrington DL, Robb Swan A, Angeles Quinto A, Nichols S, Drake A, Song T, Diwakar M, Huang CW, Risbrough VB, Dale A, Bartsch H, Matthews S, Huang JW, Lee RR, Baker DG. Resting-State Magnetoencephalography Reveals Different Patterns of Aberrant Functional Connectivity in Combat-Related Mild Traumatic Brain Injury. J Neurotrauma. 2017 Apr 01; 34(7):1412-1426. PMID: 27762653.
      View in: PubMed
    22. Ahmari SE, Risbrough VB, Geyer MA, Simpson HB. Prepulse Inhibition Deficits in Obsessive-Compulsive Disorder are More Pronounced in Females. Neuropsychopharmacology. 2016 12; 41(13):2963-2964. PMID: 27818517.
      View in: PubMed
    23. Glenn DE, Acheson DT, Geyer MA, Nievergelt CM, Baker DG, Risbrough VB. HIGH AND LOW THRESHOLD FOR STARTLE REACTIVITY ASSOCIATED WITH PTSD SYMPTOMS BUT NOT PTSD RISK: EVIDENCE FROM A PROSPECTIVE STUDY OF ACTIVE DUTY MARINES. Depress Anxiety. 2016 Mar; 33(3):192-202. PMID: 26878585.
      View in: PubMed
    24. Steinman SA, Ahmari SE, Choo T, Kimeldorf MB, Feit R, Loh S, Risbrough V, Geyer MA, Steinglass JE, Wall M, Schneier FR, Fyer AJ, Simpson HB. PREPULSE INHIBITION DEFICITS ONLY IN FEMALES WITH OBSESSIVE-COMPULSIVE DISORDER. Depress Anxiety. 2016 Mar; 33(3):238-46. PMID: 26878422; PMCID: PMC4806386 [Available on 03/01/17].
    25. Minassian A, Baker DG, Risbrough VB. Heart Rate Variability and Posttraumatic Stress Disorder. JAMA Psychiatry. 2016 Feb; 73(2):178-9. PMID: 26720754.
      View in: PubMed
    26. Risbrough VB, Glenn DE, Baker DG. On the Road to Translation for PTSD Treatment: Theoretical and Practical Considerations of the Use of Human Models of Conditioned Fear for Drug Development. Curr Top Behav Neurosci. 2016; 28:173-96. PMID: 27311760.
      View in: PubMed
    27. Yurgil KA, Clifford RE, Risbrough VB, Geyer MA, Huang M, Barkauskas DA, Vasterling JJ. Prospective Associations Between Traumatic Brain Injury and Postdeployment Tinnitus in Active-Duty Marines. J Head Trauma Rehabil. 2016 Jan-Feb; 31(1):30-9. PMID: 25699623.
      View in: PubMed
    28. Toth M, Flandreau EI, Deslauriers J, Geyer MA, Mansuy IM, Merlo Pich E, Risbrough VB. Overexpression of Forebrain CRH During Early Life Increases Trauma Susceptibility in Adulthood. Neuropsychopharmacology. 2016 May; 41(6):1681-90. PMID: 26538448.
      View in: PubMed
    29. Mandyam CD, Schilling JM, Cui W, Egawa J, Niesman IR, Kellerhals SE, Staples MC, Busija AR, Risbrough VB, Posadas E, Grogman GC, Chang JW, Roth DM, Patel PM, Patel HH, Head BP. Neuron-Targeted Caveolin-1 Improves Molecular Signaling, Plasticity, and Behavior Dependent on the Hippocampus in Adult and Aged Mice. Biol Psychiatry. 2017 01 15; 81(2):101-110. PMID: 26592463.
      View in: PubMed
    30. Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer MA, Risbrough VB. Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 2015 Oct; 72(10):979-86. PMID: 26353072.
      View in: PubMed
    31. Acheson DT, Risbrough VB. Oxytocin enhancement of fear extinction: a new target for facilitating exposure-based treatments? Biol Psychiatry. 2015 Aug 01; 78(3):154-5. PMID: 26143973.
      View in: PubMed
    32. Acheson DT, Eyler LT, Resovsky J, Tsan E, Risbrough VB. Fear extinction memory performance in a sample of stable, euthymic patients with bipolar disorder. J Affect Disord. 2015 Oct 01; 185:230-8. PMID: 26247493.
      View in: PubMed
    33. Higa KK, Ji B, Buell MR, Risbrough VB, Powell SB, Young JW, Geyer MA, Zhou X. Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice. Int J Neuropsychopharmacol. 2015 Jun 02; 18(11):pyv063. PMID: 26037489; PMCID: PMC4756721.
    34. Li X, Kaczanowska K, Finn MG, Markou A, Risbrough VB. The GABA(B) receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats. Neuropharmacology. 2015 Oct; 97:357-64. PMID: 26002628; PMCID: PMC4537349 [Available on 10/01/16].
    35. Norman SB, Haller M, Spadoni AD, Drummond SP, Risbrough V, Hamblen JL, Trim RS, Blanes EX. Maximizing the utility of a single site randomized controlled psychotherapy trial. Contemp Clin Trials. 2015 May; 42:244-51. PMID: 25933919.
      View in: PubMed
    36. Acheson DT, Feifel D, Kamenski M, Mckinney R, Risbrough VB. Intranasal oxytocin administration prior to exposure therapy for arachnophobia impedes treatment response. Depress Anxiety. 2015 Jun; 32(6):400-7. PMID: 25826649.
      View in: PubMed
    37. Breen MS, Maihofer AX, Glatt SJ, Tylee DS, Chandler SD, Tsuang MT, Risbrough VB, Baker DG, O'Connor DT, Nievergelt CM, Woelk CH. Gene networks specific for innate immunity define post-traumatic stress disorder. Mol Psychiatry. 2015 Dec; 20(12):1538-45. PMID: 25754082; PMCID: PMC4565790.
    38. Meyer MD, Risbrough VB, Liang J, Boutelle KN. Pavlovian conditioning to hedonic food cues in overweight and lean individuals. Appetite. 2015 Apr; 87:56-61. PMID: 25526826.
      View in: PubMed
    39. Flandreau E, Risbrough V, Lu A, Ableitner M, Geyer MA, Holsboer F, Deussing JM. Cell type-specific modifications of corticotropin-releasing factor (CRF) and its type 1 receptor (CRF1) on startle behavior and sensorimotor gating. Psychoneuroendocrinology. 2015 Mar; 53:16-28. PMID: 25575243; PMCID: PMC4364548.
    40. Boutelle KN, Liang J, Knatz S, Matheson B, Risbrough V, Strong D, Rhee KE, Craske MG, Zucker N, Bouton ME. Design and implementation of a study evaluating extinction processes to food cues in obese children: the Intervention for Regulations of Cues Trial (iROC). Contemp Clin Trials. 2015 Jan; 40:95-104. PMID: 25461494; PMCID: PMC4314468.
    41. Nievergelt CM, Maihofer AX, Mustapic M, Yurgil KA, Schork NJ, Miller MW, Logue MW, Geyer MA, Risbrough VB, O'Connor DT, Baker DG. Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene. Psychoneuroendocrinology. 2015 Jan; 51:459-71. PMID: 25456346.
      View in: PubMed
    42. Acheson DT, Geyer MA, Baker DG, Nievergelt CM, Yurgil K, Risbrough VB. Conditioned fear and extinction learning performance and its association with psychiatric symptoms in active duty Marines. Psychoneuroendocrinology. 2015 Jan; 51:495-505. PMID: 25444643; PMCID: PMC4345165.
    43. Marshall AJ, Acheson DT, Risbrough VB, Straus LD, Drummond SP. Fear conditioning, safety learning, and sleep in humans. J Neurosci. 2014 Aug 27; 34(35):11754-60. PMID: 25164670.
      View in: PubMed
    44. Huang MX, Yurgil KA, Robb A, Angeles A, Diwakar M, Risbrough VB, Nichols SL, McLay R, Theilmann RJ, Song T, Huang CW, Lee RR, Baker DG. Voxel-wise resting-state MEG source magnitude imaging study reveals neurocircuitry abnormality in active-duty service members and veterans with PTSD. Neuroimage Clin. 2014; 5:408-19. PMID: 25180160; PMCID: PMC4145534.
    45. Naviaux JC, Schuchbauer MA, Li K, Wang L, Risbrough VB, Powell SB, Naviaux RK. Reversal of autism-like behaviors and metabolism in adult mice with single-dose antipurinergic therapy. Transl Psychiatry. 2014 Jun 17; 4:e400. PMID: 24937094; PMCID: PMC4080315.
    46. Huang MX, Nichols S, Baker DG, Robb A, Angeles A, Yurgil KA, Drake A, Levy M, Song T, McLay R, Theilmann RJ, Diwakar M, Risbrough VB, Ji Z, Huang CW, Chang DG, Harrington DL, Muzzatti L, Canive JM, Christopher Edgar J, Chen YH, Lee RR. Single-subject-based whole-brain MEG slow-wave imaging approach for detecting abnormality in patients with mild traumatic brain injury. Neuroimage Clin. 2014; 5:109-19. PMID: 25009772; PMCID: PMC4087185.
    47. Minassian A, Geyer MA, Baker DG, Nievergelt CM, O'Connor DT, Risbrough VB. Heart rate variability characteristics in a large group of active-duty marines and relationship to posttraumatic stress. Psychosom Med. 2014 May; 76(4):292-301. PMID: 24804881; PMCID: PMC4062545.
    48. Schilling JM, Cui W, Godoy JC, Risbrough VB, Niesman IR, Roth DM, Patel PM, Drummond JC, Patel HH, Zemljic-Harpf AE, Head BP. Long-term atorvastatin treatment leads to alterations in behavior, cognition, and hippocampal biochemistry. Behav Brain Res. 2014 Jul 01; 267:6-11. PMID: 24657594; PMCID: PMC4059187.
    49. Risbrough V, Ji B, Hauger R, Zhou X. Generation and characterization of humanized mice carrying COMT158 Met/Val alleles. Neuropsychopharmacology. 2014 Jul; 39(8):1823-32. PMID: 24509724; PMCID: PMC4059890.
    50. Acheson DT, Geyer MA, Risbrough VB. Psychophysiology in the study of psychological trauma: where are we now and where do we need to be? Curr Top Behav Neurosci. 2014; 21:157-83. PMID: 25158622.
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    51. Gresack JE, Seymour PA, Schmidt CJ, Risbrough VB. Inhibition of phosphodiesterase 10A has differential effects on dopamine D1 and D2 receptor modulation of sensorimotor gating. Psychopharmacology (Berl). 2014 May; 231(10):2189-97. PMID: 24363077; PMCID: PMC4017785.
    52. van Enkhuizen J, Acheson D, Risbrough V, Drummond S, Geyer MA, Young JW. Sleep deprivation impairs performance in the 5-choice continuous performance test: similarities between humans and mice. Behav Brain Res. 2014 Mar 15; 261:40-8. PMID: 24333377; PMCID: PMC3937379.
    53. Toth M, Gresack JE, Bangasser DA, Plona Z, Valentino RJ, Flandreau EI, Mansuy IM, Merlo-Pich E, Geyer MA, Risbrough VB. Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice. Neuropsychopharmacology. 2014 May; 39(6):1409-19. PMID: 24326400.
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    54. Toth M, Gresack JE, Hauger RL, Halberstadt AL, Risbrough VB. The role of PKC signaling in CRF-induced modulation of startle. Psychopharmacology (Berl). 2013 Oct; 229(4):579-89. PMID: 23722830; PMCID: PMC3784645.
    55. Acheson D, Feifel D, de Wilde S, McKinney R, Lohr J, Risbrough V. The effect of intranasal oxytocin treatment on conditioned fear extinction and recall in a healthy human sample. Psychopharmacology (Berl). 2013 Sep; 229(1):199-208. PMID: 23644911.
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    56. Liu X, Hong SI, Park SJ, Dela Peña JB, Che H, Yoon SY, Kim DH, Kim JM, Cai M, Risbrough V, Geyer MA, Shin CY, Cheong JH, Park H, Lew JH, Ryu JH. The ameliorating effects of 5,7-dihydroxy-6-methoxy-2(4-phenoxyphenyl)-4H-chromene-4-one, an oroxylin A derivative, against memory impairment and sensorimotor gating deficit in mice. Arch Pharm Res. 2013 Jul; 36(7):854-63. PMID: 23543630.
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    57. Tatro ET, Risbrough V, Soontornniyomkij B, Young J, Shumaker-Armstrong S, Jeste DV, Achim CL. Short-term recognition memory correlates with regional CNS expression of microRNA-138 in mice. Am J Geriatr Psychiatry. 2013 May; 21(5):461-73. PMID: 23570889; PMCID: PMC3660985.
    58. Toth M, Ziegler M, Sun P, Gresack J, Risbrough V. Impaired conditioned fear response and startle reactivity in epinephrine-deficient mice. Behav Pharmacol. 2013 Feb; 24(1):1-9. PMID: 23268986; PMCID: PMC3558035.
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