Guido Frank

Title(s)Professor In Residence, Psychiatry
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
ORCID ORCID Icon0000-0002-6590-3441 Additional info
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    Collapse Biography 
    Collapse Education and Training
    Ludwig-Maximilians-University Munich, Munich, GermanyM.D.
    Collapse Awards and Honors
    1997Christina Barz-Scholarship for the Promotion of Research in the Field of Eating Disorders
    2000Obesity and Nutrition Research Center Pilot Research Award, University of Pittsburgh, PA
    2001NARSAD Young Investigator Award
    2004Society of Biological Psychiatry Lilly Travel Fellowship Award
    2004American Society of Clinical Psychopharmacology (ASCP) Travel Fellowship
    2004AACAP Outstanding Child and Adolescent Psychiatry Resident Award
    2005Fellowship Award for the Group for the Advancement of Psychiatry (GAP)
    2005American Academy of Child and Adolescent Psychiatry Presidential Scholar Award
    2005West Coast College of Biological Psychiatry Junior Faculty Research Award
    2005American College of Neuropsychopharmacology Memorial Travel Award
    2006Mayo Clinic Psychiatric Genomics Course Teaching Prize
    2008Developmental Psychobiologic Research Group Scientific Poster Award
    2008Developmental Psychobiologic Research Group Pilot Research Award
    2008Minority Access to Research Career Program (NIMH) Mentor Recognition
    2008Davis Foundation Award / Klarman Family Foundation Grants Program in Eating Disor
    2010Developmental Psychobiologic Research Group Kaufman Scientific Award
    2017Vitals Patients’ Choice Award 2016
    2019Eating Disorder Foundation Greg Hueni Memorial Award for Excellence in Research
    2020Teaching Excellence Award, UCSD Department of Psychiatry, Child and Adolescent Training Program
    2022Rady Children's Hospital CFP Award for Excellence in Clinical Care, Research and Teaching

    Collapse Overview 

    Collapse Research 
    Collapse Research Activities and Funding
    Developing a computational electroencephalogram (EEG) paradigm to study prediction error in anorexia nervosa
    NIH R21MH120355Aug 1, 2020 - May 31, 2022
    Role: Principal Investigator
    Toward understanding dopamine receptor contributions to prediction error and reversal learning in anorexia nervosa
    NIH R21MH120475Aug 1, 2019 - Apr 30, 2021
    Role: Principal Investigator
    Neural Effects of Negative Affect on Food Choices and Reward Processing In Individuals with Binge Eating Episodes
    NIH R01MH112681Dec 26, 2017 - Oct 31, 2022
    Role: Principal Investigator
    Taste reward circuits and prediction error define eating disorder psychopathology
    NIH R01MH103436Apr 1, 2014 - Dec 31, 2019
    Role: Principal Investigator
    The application of Virtual Reality in the Treatment of Anorexia Nervosa
    Children’s Hospital Colorado Foundation Jan 1, 2013 - Dec 31, 2013
    Role: Principal Investigator
    Brain Reward Circuits and Computational Modeling in Adolescent Anorexia Nervosa
    NIH R01MH096777Jul 26, 2012 - May 31, 2017
    Role: Principal Investigator
    Brain Reward-Pathway Function and Neurocomputational Modeling in Anorexia Nervosa
    NIH K23MH080135Jul 29, 2008 - Apr 30, 2013
    Role: Principal Investigator
    The Brain Reward System Across the Major Eating Disorders and its Relationship to Genotype
    Davis Foundation Award of the Klarman Family Foundation Jun 1, 2008 - Feb 28, 2011
    Role: Principal Investigator
    Development of a Method for Taste Stimulation in the Functional Magnetic Resonance Imaging Environment
    Obesity and Nutrition Research Center, University of Pittsburgh, PA Mar 30, 2000 - Jun 30, 2001
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Weight gained during treatment predicts 6-month body mass index in a large sample of patients with anorexia nervosa using ensemble machine learning. Int J Eat Disord. 2024 Apr 12. Frank GKW, Stoddard JJ, Brown T, Gowin J, Kaye WH. PMID: 38610100.
      View in: PubMed   Mentions:
    2. Adverse childhood experiences, low self-esteem, and salient stimulus response in eating disorders. Eur Eat Disord Rev. 2024 Feb 13. Lagan S, Shott ME, Frank GKW. PMID: 38349113.
      View in: PubMed   Mentions:    Fields:    
    3. Examining anxious temperament in anorexia nervosa: Behavioural inhibition and intolerance of uncertainty and their contribution to trait anxiety in adolescents with anorexia nervosa. J Affect Disord. 2024 Mar 01; 348:116-123. Sternheim LC, Bijsterbosch JM, Wever MCM, van Elburg AA, Frank GKW. PMID: 38110154.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Noradrenergic control of neurobehavior in human binge-eating disorder and obesity (NOBEAD): A smartphone-supported behavioral emotion regulation intervention study protocol integrating molecular brain imaging. Int J Eat Disord. 2024 Jan; 57(1):206-220. Hesse S, Rullmann M, Zientek F, Schewe D, Becker GA, Patt M, Meyer PM, Juarascio AS, Frank GKW, Sabri O, Hilbert A. PMID: 37941314.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Neural Response to Expecting a Caloric Sweet Taste Stimulus Predicts Body Mass Index Longitudinally Among Young Adult Women With Anorexia Nervosa. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Mar; 9(3):298-304. Gorrell S, Shott ME, Pryor T, Frank GKW. PMID: 37506848; PMCID: PMC10811282.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    6. Anticipatory and consummatory pleasure in eating disorders. J Eat Disord. 2022 Nov 12; 10(1):161. Dolan SC, Reilly EE, Brown TA, Shott ME, Frank GKW. PMID: 36371268; PMCID: PMC9652864.
      View in: PubMed   Mentions: 2  
    7. Effect of stimulant medication on loss of control eating in youth with attention deficit/hyperactivity disorder: a prospective, observational case series study protocol. J Eat Disord. 2022 Nov 01; 10(1):152. Keshen AR, Hilbert A, Taylor V, Harris AL, Trappenberg N, Sadek J, Frank GKW, Murray SB. PMID: 36320022; PMCID: PMC9628055.
      View in: PubMed   Mentions: 1  
    8. Brain reward response in adolescents and young adults with anorexia nervosa is moderated by changes in body weight and sweetness perception. Int J Eat Disord. 2022 Sep 22. Frank GKW, Shott ME, Pryor T, Swindle S, Stoddard J. PMID: 36135728.
      View in: PubMed   Mentions: 1     Fields:    
    9. Trait anxiety is associated with amygdala expectation and caloric taste receipt response across eating disorders. Neuropsychopharmacology. 2022 Sep 13. Frank GKW, Shott ME, Pryor T, Swindle S, Nguyen T, Stoddard J. PMID: 36100656.
      View in: PubMed   Mentions: 3     Fields:    
    10. Ketogenic diet and ketamine infusion treatment to target chronic persistent eating disorder psychopathology in anorexia nervosa: a pilot study. Eat Weight Disord. 2022 Dec; 27(8):3751-3757. Calabrese L, Scolnick B, Zupec-Kania B, Beckwith C, Costello K, Frank GKW. PMID: 35997954; PMCID: PMC9803738.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    11. Brain Structure in Acutely Underweight and Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis by the ENIGMA Eating Disorders Working Group. Biol Psychiatry. 2022 11 01; 92(9):730-738. Walton E, Bernardoni F, Batury VL, Bahnsen K, Larivière S, Abbate-Daga G, Andres-Perpiña S, Bang L, Bischoff-Grethe A, Brooks SJ, Campbell IC, Cascino G, Castro-Fornieles J, Collantoni E, D'Agata F, Dahmen B, Danner UN, Favaro A, Feusner JD, Frank GKW, Friederich HC, Graner JL, Herpertz-Dahlmann B, Hess A, Horndasch S, Kaplan AS, Kaufmann LK, Kaye WH, Khalsa SS, LaBar KS, Lavagnino L, Lazaro L, Manara R, Miles AE, Milos GF, Monteleone AM, Monteleone P, Mwangi B, O'Daly O, Pariente J, Roesch J, Schmidt UH, Seitz J, Shott ME, Simon JJ, Smeets PAM, Tamnes CK, Tenconi E, Thomopoulos SI, van Elburg AA, Voineskos AN, von Polier GG, Wierenga CE, Zucker NL, Jahanshad N, King JA, Thompson PM, Berner LA, Ehrlich S. PMID: 36031441.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    12. Associations between aerobic exercise and dopamine-related reward-processing: Informing a model of human exercise engagement. Biol Psychol. 2022 05; 171:108350. Gorrell S, Shott ME, Frank GKW. PMID: 35561818; PMCID: PMC9869713.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    13. The potential role of stimulants in treating eating disorders. Int J Eat Disord. 2022 03; 55(3):318-331. Keshen A, Bartel S, Frank GKW, Svedlund NE, Nunes A, Dixon L, Ali SI, Kaplan AS, Hay P, Touyz S, Romo-Nava F, McElroy SL. PMID: 34846763.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    14. Association of Brain Reward Response With Body Mass Index and Ventral Striatal-Hypothalamic Circuitry Among Young Women With Eating Disorders. JAMA Psychiatry. 2021 10 01; 78(10):1123-1133. Frank GKW, Shott ME, Stoddard J, Swindle S, Pryor TL. PMID: 34190963; PMCID: PMC8246338.
      View in: PubMed   Mentions: 21     Fields:    Translation:Humans
    15. Open science practices for eating disorders research. Int J Eat Disord. 2021 10; 54(10):1719-1729. Burke NL, Frank GKW, Hilbert A, Hildebrandt T, Klump KL, Thomas JJ, Wade TD, Walsh BT, Wang SB, Weissman RS. PMID: 34555191; PMCID: PMC9107337.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    16. Understanding implicit and explicit learning in adolescents with and without anorexia nervosa. J Eat Disord. 2021 Jun 29; 9(1):77. Sternheim LC, Wickham MI, Danner UN, Maddox TW, Filoteo VJ, Shott ME, Frank GKW. PMID: 34187577; PMCID: PMC8243584.
      View in: PubMed   Mentions:
    17. Introduction to a special issue on eating disorders and gastrointestinal symptoms-The chicken or the egg? Int J Eat Disord. 2021 06; 54(6):911-912. Frank GKW, Golden NH, Murray HB. PMID: 34028860.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    18. From Desire to Dread-A Neurocircuitry Based Model for Food Avoidance in Anorexia Nervosa. J Clin Med. 2021 May 21; 10(11). Frank GKW. PMID: 34063884; PMCID: PMC8196668.
      View in: PubMed   Mentions: 2  
    19. I know I am not out of control, but I just cannot shake the feeling: exploring feeling out of control in eating disorders. Eat Weight Disord. 2022 Mar; 27(2):839-845. Adler L, Brown TA, Shott ME, Swindle S, Frank GKW. PMID: 33993434.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Persistence, Reward Dependence, and Sensitivity to Reward Are Associated With Unexpected Salience Response in Girls but Not in Adult Women: Implications for Psychiatric Vulnerabilities. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Nov; 7(11):1170-1182. Frank GKW, Shott ME, Sternheim LC, Swindle S, Pryor TL. PMID: 33872764.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    21. A longitudinal case series of IM ketamine for patients with severe and enduring eating disorders and comorbid treatment-resistant depression. Clin Case Rep. 2021 May; 9(5):e03869. Schwartz T, Trunko ME, Feifel D, Lopez E, Peterson D, Frank GKW, Kaye W. PMID: 34026123; PMCID: PMC8117825.
      View in: PubMed   Mentions: 13  
    22. Body size overestimation in anorexia nervosa: Contributions of cognitive, affective, tactile and visual information. Psychiatry Res. 2021 03; 297:113705. Brown TA, Shott ME, Frank GKW. PMID: 33472094.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Is the pharmacological management of bulimia nervosa plausible? Expert Opin Pharmacother. 2020 12; 21(17):2073-2075. Frank GKW. PMID: 32772753; PMCID: PMC7718301.
      View in: PubMed   Mentions:    Fields:    
    24. Eye blink and reward prediction error response in anorexia nervosa. Int J Eat Disord. 2020 09; 53(9):1544-1549. Frank GKW, Kalina C, DeGuzman MC, Shott ME. PMID: 32567716.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    25. IJED support for eating disorders research in the time of COVID-19. Int J Eat Disord. 2020 07; 53(7):1017-1020. Weissman RS, Klump KL, Wade T, Thomas JJ, Frank G, Waller G. PMID: 32385900; PMCID: PMC7272887.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
    26. Pharmacotherapeutic strategies for the treatment of anorexia nervosa - too much for one drug? Expert Opin Pharmacother. 2020 Jun; 21(9):1045-1058. Frank GKW. PMID: 32281881; PMCID: PMC7491209.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    27. Neuroimaging and eating disorders. Curr Opin Psychiatry. 2019 11; 32(6):478-483. Frank GKW. PMID: 31306246; PMCID: PMC6768759.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    28. Editorial to the virtual issue highlighting neuroscience based research in eating disorders to mark the 49th Society for Neuroscience Annual Meeting. Int J Eat Disord. 2019 11; 52(11):1332-1335. Frank GKW. PMID: 31524987.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    29. The Neurobiology of Eating Disorders. Child Adolesc Psychiatr Clin N Am. 2019 10; 28(4):629-640. Frank GKW, Shott ME, DeGuzman MC. PMID: 31443880; PMCID: PMC6709695.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    30. Recent advances in understanding anorexia nervosa. F1000Res. 2019; 8. Frank GKW, Shott ME, DeGuzman MC. PMID: 31069054; PMCID: PMC6480957.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    31. Motivation to eat and not to eat - The psycho-biological conflict in anorexia nervosa. Physiol Behav. 2019 07 01; 206:185-190. Frank GKW, DeGuzman MC, Shott ME. PMID: 30980856; PMCID: PMC6520121.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    32. Association of Brain Reward Learning Response With Harm Avoidance, Weight Gain, and Hypothalamic Effective Connectivity in Adolescent Anorexia Nervosa. JAMA Psychiatry. 2018 10 01; 75(10):1071-1080. Frank GKW, DeGuzman MC, Shott ME, Laudenslager ML, Rossi B, Pryor T. PMID: 30027213; PMCID: PMC6233809.
      View in: PubMed   Mentions: 43     Fields:    Translation:Humans
    33. Neural correlates of taste reward value across eating disorders. Psychiatry Res Neuroimaging. 2019 06 30; 288:76-84. Olsavsky AK, Shott ME, DeGuzman MC, Frank GKW. PMID: 30149963; PMCID: PMC6379157.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    34. Dopamine D2 -141C Ins/Del and Taq1A polymorphisms, body mass index, and prediction error brain response. Transl Psychiatry. 2018 05 23; 8(1):102. Frank GKW, Shott ME, DeGuzman MC, Smolen A. PMID: 29795192; PMCID: PMC5966465.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    35. Cortical thickness patterns as state biomarker of anorexia nervosa. Int J Eat Disord. 2018 03; 51(3):241-249. Lavagnino L, Mwangi B, Cao B, Shott ME, Soares JC, Frank GKW. PMID: 29412456; PMCID: PMC5843530.
      View in: PubMed   Mentions: 24     Fields:    Translation:Humans
    36. Toward valid and reliable brain imaging results in eating disorders. Int J Eat Disord. 2018 03; 51(3):250-261. Frank GKW, Favaro A, Marsh R, Ehrlich S, Lawson EA. PMID: 29405338; PMCID: PMC7449370.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    37. The current status of cognitive behavioral therapy for eating disorders: Marking the 51st Annual Convention of the Association of Behavioral and Cognitive Therapies. Int J Eat Disord. 2017 12; 50(12):1444-1446. Weissman RS, Frank GKW, Klump KL, Thomas JJ, Wade T, Waller G. PMID: 29210517.
      View in: PubMed   Mentions: 4     Fields:    
    38. Ross D. Crosby: Scholar, teacher, mentor, and friend. Introducing a virtual issue honoring the contributions of Ross D. Crosby to the field of eating disorders. Int J Eat Disord. 2017 10; 50(10):1121-1123. Weissman RS, Frank GKW, Klump KL, Thomas JJ, Wade T, Waller G. PMID: 28902416.
      View in: PubMed   Mentions:    Fields:    
    39. Structural Neuroimaging of Anorexia Nervosa: Future Directions in the Quest for Mechanisms Underlying Dynamic Alterations. Biol Psychiatry. 2018 02 01; 83(3):224-234. King JA, Frank GKW, Thompson PM, Ehrlich S. PMID: 28967386; PMCID: PMC6053269.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    40. The partial dopamine D2 receptor agonist aripiprazole is associated with weight gain in adolescent anorexia nervosa. Int J Eat Disord. 2017 Apr; 50(4):447-450. Frank GK, Shott ME, Hagman JO, Schiel MA, DeGuzman MC, Rossi B. PMID: 28334444; PMCID: PMC5392387.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    41. Association of Elevated Reward Prediction Error Response With Weight Gain in Adolescent Anorexia Nervosa. Am J Psychiatry. 2017 06 01; 174(6):557-565. DeGuzman M, Shott ME, Yang TT, Riederer J, Frank GKW. PMID: 28231717; PMCID: PMC5607032.
      View in: PubMed   Mentions: 38     Fields:    Translation:Humans
    42. Brain Reward Processing in Eating Disorders: Opportunities to Build Upon? J Am Acad Child Adolesc Psychiatry. 2016 11; 55(11):929-930. Frank GK. PMID: 27806859.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    43. Prediction error and somatosensory insula activation in women recovered from anorexia nervosa. J Psychiatry Neurosci. 2016 08; 41(5):304-11. Frank GK, Collier S, Shott ME, O'Reilly RC. PMID: 26836623; PMCID: PMC5008919.
      View in: PubMed   Mentions: 23     Fields:    Translation:Humans
    44. Understanding Neuronal Architecture in Obesity through Analysis of White Matter Connection Strength. Front Hum Neurosci. 2016; 10:271. Riederer JW, Shott ME, Deguzman M, Pryor TL, Frank GK. PMID: 27375463; PMCID: PMC4893484.
      View in: PubMed   Mentions: 14  
    45. Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder. Neuropsychopharmacology. 2016 11; 41(12):2951-2960. Sacchet MD, Ho TC, Connolly CG, Tymofiyeva O, Lewinn KZ, Han LK, Blom EH, Tapert SF, Max JE, Frank GK, Paulus MP, Simmons AN, Gotlib IH, Yang TT. PMID: 27238621; PMCID: PMC5061890.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    46. The Role of Psychotropic Medications in the Management of Anorexia Nervosa: Rationale, Evidence and Future Prospects. CNS Drugs. 2016 May; 30(5):419-42. Frank GK, Shott ME. PMID: 27106297; PMCID: PMC4873415.
      View in: PubMed   Mentions: 28     Fields:    Translation:HumansAnimals
    47. Extremes of eating are associated with reduced neural taste discrimination. Int J Eat Disord. 2016 Jun; 49(6):603-12. Frank GK, Shott ME, Keffler C, Cornier MA. PMID: 27083785; PMCID: PMC4900931.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    48. Speaking of That: Terms to Avoid or Reconsider in the Eating Disorders Field. Int J Eat Disord. 2016 Apr; 49(4):349-53. Weissman RS, Becker AE, Bulik CM, Frank GK, Klump KL, Steiger H, Strober M, Thomas J, Waller G, Walsh BT. PMID: 27084795.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    49. Preface for International Journal of Eating Disorders special issue medical complications in eating disorders. Int J Eat Disord. 2016 Mar; 49(3):215. Frank GK. PMID: 26876572.
      View in: PubMed   Mentions:    Fields:    
    50. The medical complications associated with purging. Int J Eat Disord. 2016 Mar; 49(3):249-59. Forney KJ, Buchman-Schmitt JM, Keel PK, Frank GK. PMID: 26876429; PMCID: PMC4803618.
      View in: PubMed   Mentions: 33     Fields:    Translation:Humans
    51. Anorexia nervosa. Nat Rev Dis Primers. 2015 11 26; 1:15074. Treasure J, Zipfel S, Micali N, Wade T, Stice E, Claudino A, Schmidt U, Frank GK, Bulik CM, Wentz E. PMID: 27189821.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    52. Aripiprazole, a partial dopamine agonist to improve adolescent anorexia nervosa-A case series. Int J Eat Disord. 2016 May; 49(5):529-533. Frank GK. PMID: 26593328.
      View in: PubMed   Mentions: 9     Fields:    
    53. Altered sensitization patterns to sweet food stimuli in patients recovered from anorexia and bulimia nervosa. Psychiatry Res. 2015 Dec 30; 234(3):305-13. Wagner A, Simmons AN, Oberndorfer TA, Frank GK, McCurdy-McKinnon D, Fudge JL, Yang TT, Paulus MP, Kaye WH. PMID: 26596520; PMCID: PMC6547368.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    54. Greater Insula White Matter Fiber Connectivity in Women Recovered from Anorexia Nervosa. Neuropsychopharmacology. 2016 Jan; 41(2):498-507. Shott ME, Pryor TL, Yang TT, Frank GK. PMID: 26076832; PMCID: PMC5130125.
      View in: PubMed   Mentions: 36     Fields:    Translation:Humans
    55. Body size overestimation and its association with body mass index, body dissatisfaction, and drive for thinness in anorexia nervosa. Eat Weight Disord. 2015 Dec; 20(4):449-55. Hagman J, Gardner RM, Brown DL, Gralla J, Fier JM, Frank GK. PMID: 25929983.
      View in: PubMed   Mentions: 22     Fields:    Translation:Humans
    56. Advances from neuroimaging studies in eating disorders. CNS Spectr. 2015 Aug; 20(4):391-400. Frank GK. PMID: 25902917; PMCID: PMC4989857.
      View in: PubMed   Mentions: 53     Fields:    Translation:Humans
    57. Recent advances in neuroimaging to model eating disorder neurobiology. Curr Psychiatry Rep. 2015 Apr; 17(4):559. Frank GK. PMID: 25749747.
      View in: PubMed   Mentions: 15     Fields:    Translation:Humans
    58. What causes eating disorders, and what do they cause? Biol Psychiatry. 2015 Apr 01; 77(7):602-3. Frank GK. PMID: 25766685.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    59. Could dopamine agonists aid in drug development for anorexia nervosa? Front Nutr. 2014; 1:19. Frank GK. PMID: 25988121; PMCID: PMC4428488.
      View in: PubMed   Mentions: 13  
    60. The effects of energy balance, obesity-proneness and sex on the neuronal response to sweet taste. Behav Brain Res. 2015 Feb 01; 278:446-52. Cornier MA, Shott ME, Thomas EA, Bechtell JL, Bessesen DH, Tregellas JR, Frank GK. PMID: 25447301; PMCID: PMC4382429.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    61. Music to my brain: could music training be used to improve adolescent brain development? J Am Acad Child Adolesc Psychiatry. 2014 Nov; 53(11):1147-9. Frank GK. PMID: 25440303.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    62. Emotion-Dependent Functional Connectivity of the Default Mode Network in Adolescent Depression. Biol Psychiatry. 2015 Nov 01; 78(9):635-46. Ho TC, Connolly CG, Henje Blom E, LeWinn KZ, Strigo IA, Paulus MP, Frank G, Max JE, Wu J, Chan M, Tapert SF, Simmons AN, Yang TT. PMID: 25483399; PMCID: PMC4362932.
      View in: PubMed   Mentions: 96     Fields:    Translation:Humans
    63. Simulating category learning and set shifting deficits in patients weight-restored from anorexia nervosa. Neuropsychology. 2014 Sep; 28(5):741-51. Filoteo JV, Paul EJ, Ashby FG, Frank GK, Helie S, Rockwell R, Bischoff-Grethe A, Wierenga C, Kaye WH. PMID: 24799291; PMCID: PMC4143467.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    64. Reduced salience and default mode network activity in women with anorexia nervosa. J Psychiatry Neurosci. 2014 May; 39(3):178-88. McFadden KL, Tregellas JR, Shott ME, Frank GK. PMID: 24280181; PMCID: PMC3997603.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    65. Response to Keating and Rossell. Am J Psychiatry. 2013 Nov; 170(11):1367. Frank GK, Shott ME, Hagman JO, Mittal VA. PMID: 24185248; PMCID: PMC4074904.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    66. Altered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa. Am J Psychiatry. 2013 Oct; 170(10):1143-51. Oberndorfer TA, Frank GK, Simmons AN, Wagner A, McCurdy D, Fudge JL, Yang TT, Paulus MP, Kaye WH. PMID: 23732817; PMCID: PMC3971875.
      View in: PubMed   Mentions: 96     Fields:    Translation:Humans
    67. Altered brain reward circuits in eating disorders: chicken or egg? Curr Psychiatry Rep. 2013 Oct; 15(10):396. Frank GK. PMID: 23963630; PMCID: PMC3888645.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    68. Alterations in brain structures related to taste reward circuitry in ill and recovered anorexia nervosa and in bulimia nervosa. Am J Psychiatry. 2013 Oct; 170(10):1152-60. Frank GK, Shott ME, Hagman JO, Mittal VA. PMID: 23680873; PMCID: PMC3789862.
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    69. Localized brain volume and white matter integrity alterations in adolescent anorexia nervosa. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1066-1075.e5. Frank GK, Shott ME, Hagman JO, Yang TT. PMID: 24074473; PMCID: PMC4082770.
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    70. Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents. Biol Psychiatry. 2013 Dec 15; 74(12):898-907. Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. PMID: 23910949; PMCID: PMC4103629.
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    71. Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1076-1091.e2. Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. PMID: 24074474; PMCID: PMC3825460.
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    72. White matter integrity is reduced in bulimia nervosa. Int J Eat Disord. 2013 Apr; 46(3):264-73. Mettler LN, Shott ME, Pryor T, Yang TT, Frank GK. PMID: 23354827; PMCID: PMC3722416.
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    73. Interaction between serotonin transporter and dopamine D2/D3 receptor radioligand measures is associated with harm avoidant symptoms in anorexia and bulimia nervosa. Psychiatry Res. 2013 Feb 28; 211(2):160-8. Bailer UF, Frank GK, Price JC, Meltzer CC, Becker C, Mathis CA, Wagner A, Barbarich-Marsteller NC, Bloss CS, Putnam K, Schork NJ, Gamst A, Kaye WH. PMID: 23154100; PMCID: PMC3880148.
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    74. Anorexia nervosa and obesity are associated with opposite brain reward response. Neuropsychopharmacology. 2012 Aug; 37(9):2031-46. Frank GK, Reynolds JR, Shott ME, Jappe L, Yang TT, Tregellas JR, O'Reilly RC. PMID: 22549118; PMCID: PMC3398719.
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    75. Advances in the diagnosis of anorexia nervosa and bulimia nervosa using brain imaging. Expert Opin Med Diagn. 2012 May 01; 6(3):235-244. Frank GK. PMID: 22936952; PMCID: PMC3427937.
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    76. Current status of functional imaging in eating disorders. Int J Eat Disord. 2012 Sep; 45(6):723-36. Frank GK, Kaye WH. PMID: 22532388; PMCID: PMC3872533.
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    77. Cognitive set-shifting in anorexia nervosa. Eur Eat Disord Rev. 2012 Sep; 20(5):343-9. Shott ME, Filoteo JV, Bhatnagar KA, Peak NJ, Hagman JO, Rockwell R, Kaye WH, Frank GK. PMID: 22492553; PMCID: PMC3755493.
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    78. Amygdala response and functional connectivity during emotion regulation: a study of 14 depressed adolescents. J Affect Disord. 2012 Jun; 139(1):75-84. Perlman G, Simmons AN, Wu J, Hahn KS, Tapert SF, Max JE, Paulus MP, Brown GG, Frank GK, Campbell-Sills L, Yang TT. PMID: 22401827; PMCID: PMC3340443.
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    79. Altered implicit category learning in anorexia nervosa. Neuropsychology. 2012 Mar; 26(2):191-201. Shott ME, Filoteo JV, Jappe LM, Pryor T, Maddox WT, Rollin MD, Hagman JO, Frank GK. PMID: 22201300; PMCID: PMC3295920.
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    80. A double-blind, placebo-controlled study of risperidone for the treatment of adolescents and young adults with anorexia nervosa: a pilot study. J Am Acad Child Adolesc Psychiatry. 2011 Sep; 50(9):915-24. Hagman J, Gralla J, Sigel E, Ellert S, Dodge M, Gardner R, O'Lonergan T, Frank G, Wamboldt MZ. PMID: 21871373; PMCID: PMC3171450.
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    81. Altered temporal difference learning in bulimia nervosa. Biol Psychiatry. 2011 Oct 15; 70(8):728-735. Frank GKW, Reynolds JR, Shott ME, O'Reilly RC. PMID: 21718969; PMCID: PMC3186835.
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    82. Heightened sensitivity to reward and punishment in anorexia nervosa. Int J Eat Disord. 2011 May; 44(4):317-24. Jappe LM, Frank GK, Shott ME, Rollin MD, Pryor T, Hagman JO, Yang TT, Davis E. PMID: 21472750; PMCID: PMC3072848.
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    83. Altered fimbria-fornix white matter integrity in anorexia nervosa predicts harm avoidance. Psychiatry Res. 2011 May 31; 192(2):109-16. Kazlouski D, Rollin MD, Tregellas J, Shott ME, Jappe LM, Hagman JO, Pryor T, Yang TT, Frank GK. PMID: 21498054; PMCID: PMC3085716.
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    84. Heightened fear of uncertainty in anorexia and bulimia nervosa. Int J Eat Disord. 2012 Mar; 45(2):227-32. Frank GK, Roblek T, Shott ME, Jappe LM, Rollin MD, Hagman JO, Pryor T. PMID: 21495057; PMCID: PMC3140557.
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    85. Reward and neurocomputational processes. Curr Top Behav Neurosci. 2011; 6:95-110. Frank GK. PMID: 21243472; PMCID: PMC3722417.
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    86. 5-HT₁A receptor binding is increased after recovery from bulimia nervosa compared to control women and is associated with behavioral inhibition in both groups. Int J Eat Disord. 2011 Sep; 44(6):477-87. Bailer UF, Bloss CS, Frank GK, Price JC, Meltzer CC, Mathis CA, Geyer MA, Wagner A, Becker CR, Schork NJ, Kaye WH. PMID: 20872754; PMCID: PMC4286242.
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    87. Altered striatal response to reward in bulimia nervosa after recovery. Int J Eat Disord. 2010 May; 43(4):289-94. Wagner A, Aizenstein H, Venkatraman VK, Bischoff-Grethe A, Fudge J, May JC, Frank GK, Bailer UF, Fischer L, Putnam K, Kaye WH. PMID: 19434606; PMCID: PMC4286149.
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    88. Adolescents with major depression demonstrate increased amygdala activation. J Am Acad Child Adolesc Psychiatry. 2010 Jan; 49(1):42-51. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Max JE, Bischoff-Grethe A, Lansing AE, Brown G, Strigo IA, Wu J, Paulus MP. PMID: 20215925; PMCID: PMC2935523.
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    89. Depressed adolescents demonstrate greater subgenual anterior cingulate activity. Neuroreport. 2009 Mar 04; 20(4):440-4. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Bischoff-Grethe A, Lansing AE, Wu J, Brown GG, Paulus MP. PMID: 19218875; PMCID: PMC2672880.
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    90. Adolescent subgenual anterior cingulate activity is related to harm avoidance. Neuroreport. 2009 Jan 07; 20(1):19-23. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Bischoff-Grethe A, Lansing AE, Wu J, Paulus MP. PMID: 19034055; PMCID: PMC2852645.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansCTClinical Trials
    91. Altered reward processing in women recovered from anorexia nervosa. Am J Psychiatry. 2007 Dec; 164(12):1842-9. Wagner A, Aizenstein H, Venkatraman VK, Fudge J, May JC, Mazurkewicz L, Frank GK, Bailer UF, Fischer L, Nguyen V, Carter C, Putnam K, Kaye WH. PMID: 18056239.
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    92. Increased amygdala activation is related to heart rate during emotion processing in adolescent subjects. Neurosci Lett. 2007 Nov 27; 428(2-3):109-14. Yang TT, Simmons AN, Matthews SC, Tapert SF, Bischoff-Grethe A, Frank GK, Arce E, Paulus MP. PMID: 18029095; PMCID: PMC2171034.
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    93. Sucrose activates human taste pathways differently from artificial sweetener. Neuroimage. 2008 Feb 15; 39(4):1559-69. Frank GK, Oberndorfer TA, Simmons AN, Paulus MP, Fudge JL, Yang TT, Kaye WH. PMID: 18096409.
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    94. Regional cerebral blood flow after recovery from anorexia or bulimia nervosa. Int J Eat Disord. 2007 Sep; 40(6):488-92. Frank GK, Bailer UF, Meltzer CC, Price JC, Mathis CA, Wagner A, Becker C, Kaye WH. PMID: 17525951.
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    95. Serotonin transporter binding after recovery from eating disorders. Psychopharmacology (Berl). 2007 Dec; 195(3):315-24. Bailer UF, Frank GK, Henry SE, Price JC, Meltzer CC, Becker C, Ziolko SK, Mathis CA, Wagner A, Barbarich-Marsteller NC, Putnam K, Kaye WH. PMID: 17690869.
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    96. Altered insula response to taste stimuli in individuals recovered from restricting-type anorexia nervosa. Neuropsychopharmacology. 2008 Feb; 33(3):513-23. Wagner A, Aizenstein H, Mazurkewicz L, Fudge J, Frank GK, Putnam K, Bailer UF, Fischer L, Kaye WH. PMID: 17487228.
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    97. 5HT2A receptor binding is increased in borderline personality disorder. Biol Psychiatry. 2007 Sep 15; 62(6):580-7. Soloff PH, Price JC, Meltzer CC, Fabio A, Frank GK, Kaye WH. PMID: 17448449.
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    98. Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa. Biol Psychiatry. 2007 May 01; 61(9):1090-9. Bailer UF, Frank GK, Henry SE, Price JC, Meltzer CC, Mathis CA, Wagner A, Thornton L, Hoge J, Ziolko SK, Becker CR, McConaha CW, Kaye WH. PMID: 17241616.
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    99. Neural correlates of habituation to taste stimuli in healthy women. Psychiatry Res. 2006 Jun 30; 147(1):57-67. Wagner A, Aizenstein H, Frank GK, Figurski J, May JC, Putnam K, Fischer L, Bailer UF, Henry SE, McConaha C, Vogel V, Kaye WH. PMID: 16806849.
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    100. Personality traits after recovery from eating disorders: do subtypes differ? Int J Eat Disord. 2006 May; 39(4):276-84. Wagner A, Barbarich-Marsteller NC, Frank GK, Bailer UF, Wonderlich SA, Crosby RD, Henry SE, Vogel V, Plotnicov K, McConaha C, Kaye WH. PMID: 16528697.
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    101. Altered brain activity in women recovered from bulimic-type eating disorders after a glucose challenge: a pilot study. Int J Eat Disord. 2006 Jan; 39(1):76-9. Frank GK, Wagner A, Achenbach S, McConaha C, Skovira K, Aizenstein H, Carter CS, Kaye WH. PMID: 16254868.
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    102. Positron emission tomography studies in eating disorders: multireceptor brain imaging, correlates with behavior and implications for pharmacotherapy. Nucl Med Biol. 2005 Oct; 32(7):755-61. Frank GK, Kaye WH. PMID: 16243652.
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    103. Brain imaging of serotonin after recovery from anorexia and bulimia nervosa. Physiol Behav. 2005 Sep 15; 86(1-2):15-7. Kaye WH, Bailer UF, Frank GK, Wagner A, Henry SE. PMID: 16102788.
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    104. Normal brain tissue volumes after long-term recovery in anorexia and bulimia nervosa. Biol Psychiatry. 2006 Feb 01; 59(3):291-3. Wagner A, Greer P, Bailer UF, Frank GK, Henry SE, Putnam K, Meltzer CC, Ziolko SK, Hoge J, McConaha C, Kaye WH. PMID: 16139807.
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    105. Altered brain serotonin 5-HT1A receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [carbonyl11C]WAY-100635. Arch Gen Psychiatry. 2005 Sep; 62(9):1032-41. Bailer UF, Frank GK, Henry SE, Price JC, Meltzer CC, Weissfeld L, Mathis CA, Drevets WC, Wagner A, Hoge J, Ziolko SK, McConaha CW, Kaye WH. PMID: 16143735.
      View in: PubMed   Mentions: 46     Fields:    Translation:Humans
    106. Increased dopamine D2/D3 receptor binding after recovery from anorexia nervosa measured by positron emission tomography and [11c]raclopride. Biol Psychiatry. 2005 Dec 01; 58(11):908-12. Frank GK, Bailer UF, Henry SE, Drevets W, Meltzer CC, Price JC, Mathis CA, Wagner A, Hoge J, Ziolko S, Barbarich-Marsteller N, Weissfeld L, Kaye WH. PMID: 15992780.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansCTClinical Trials
    107. Serotonin alterations in anorexia and bulimia nervosa: new insights from imaging studies. Physiol Behav. 2005 May 19; 85(1):73-81. Kaye WH, Frank GK, Bailer UF, Henry SE, Meltzer CC, Price JC, Mathis CA, Wagner A. PMID: 15869768.
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    108. Neurobiology of anorexia nervosa: clinical implications of alterations of the function of serotonin and other neuronal systems. Int J Eat Disord. 2005; 37 Suppl:S15-9; discussion S20-1. Kaye WH, Frank GK, Bailer UF, Henry SE. PMID: 15852312.
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    109. An open trial of olanzapine in anorexia nervosa. J Clin Psychiatry. 2004 Nov; 65(11):1480-2. Barbarich NC, McConaha CW, Gaskill J, La Via M, Frank GK, Achenbach S, Plotnicov KH, Kaye WH. PMID: 15554759.
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    110. Neuroimaging studies in eating disorders. CNS Spectr. 2004 Jul; 9(7):539-48. Frank GK, Bailer UF, Henry S, Wagner A, Kaye WH. PMID: 15208513.
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    111. Altered 5-HT(2A) receptor binding after recovery from bulimia-type anorexia nervosa: relationships to harm avoidance and drive for thinness. Neuropsychopharmacology. 2004 Jun; 29(6):1143-55. Bailer UF, Price JC, Meltzer CC, Mathis CA, Frank GK, Weissfeld L, McConaha CW, Henry SE, Brooks-Achenbach S, Barbarich NC, Kaye WH. PMID: 15054474; PMCID: PMC4301578.
      View in: PubMed   Mentions: 36     Fields:    Translation:HumansCells
    112. Use of nutritional supplements to increase the efficacy of fluoxetine in the treatment of anorexia nervosa. Int J Eat Disord. 2004 Jan; 35(1):10-5. Barbarich NC, McConaha CW, Halmi KA, Gendall K, Sunday SR, Gaskill J, La Via M, Frank GK, Brooks S, Plotnicov KH, Kaye WH. PMID: 14705152.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCTClinical Trials
    113. The evaluation of brain activity in response to taste stimuli--a pilot study and method for central taste activation as assessed by event-related fMRI. J Neurosci Methods. 2003 Dec 30; 131(1-2):99-105. Frank GK, Kaye WH, Carter CS, Brooks S, May C, Fissell K, Stenger VA. PMID: 14659829.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    114. Pain perception in recovered bulimia nervosa patients. Int J Eat Disord. 2003 Nov; 34(3):331-6. Stein D, Kaye WH, Matsunaga H, Myers D, Orbach I, Har-Even D, Frank G, Rao R. PMID: 12949924.
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    115. Olanzapine treatment of anorexia nervosa: a retrospective study. Int J Eat Disord. 2003 Mar; 33(2):234-7. Malina A, Gaskill J, McConaha C, Frank GK, LaVia M, Scholar L, Kaye WH. PMID: 12616591.
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