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Jeffrey Max

TitleProfessor In Residence
InstitutionUniversity of California San Diego
DepartmentPsychiatry
Address5755 Oberlin Drive, Suite 301
San Diego CA 92121
Phone858-625-0025
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    Biography

    Dr. Max was born and raised in Johannesburg, South Africa. He graduated from the University of the Witwatersrand Medical School in Johannesburg. He trained in General Psychiatry and also Child and Adolescent Psychiatry at Brown University. He began his research career at the University of Iowa where he established himself as a nationally recognized investigator in the area of psychiatric outcome of traumatic brain injury in children and adolescents. Currently he works at the University of California, San Diego where he is recognized internationally for his research in pediatric traumatic brain injury and also pediatric stroke.

    Research Interests

    Dr. Max conducts studies of pediatric traumatic brain injury and pediatric stroke. The thrust of the research is to identify brain imaging characteristics including microstructural white matter integrity and lesion location as well as psychosocial (e.g., family function, family psychiatric history, child’s pre-injury function) predictors of varied psychiatric disorders that develop after brain injury. Through the identification of outcome predictors a rational strategy for early identification and treatment of complications can be developed. Dr. Max leads a 5-year National Institutes of Health study on pediatric mild traumatic brain injury focusing on psychiatric outcome and brain imaging changes. He also investigates the neuropsychological profile of post-brain injury psychiatric disorders as an additional tool to understand the mechanism of these disorders.

    Clinical Focus

    Dr. Max is a Board Certified General Psychiatrist as well as a Board Certified Child and Adolescent Psychiatrist. He treats children and adolescents and adults often within the same family. His general psychiatric practice consists of people with behavioral disorders (such as ADHD), pervasive developmental disorder, depressive disorders, bipolar disorder, substance abuse, and anxiety syndromes. He conducts medication management, individual psychotherapy, couple’s therapy, and family therapy. He is trained in the McMaster Model of Family Therapy. He has specialized experience with psychiatric complications of brain injury including traumatic brain injury, epilepsy, stroke, pre-natal alcohol or drug exposure. Dr. Max teaches residents at University of California, San Diego in the Child and Adolescent Psychiatry training program.


    Collapse Research 
    Collapse Research Activities and Funding
    Magnetoencephalography and Neurobehavioral Outcome of Pediatric Traumatic Brain Injury
    NIH/NICHD R01HD088438Mar 10, 2017 - Feb 28, 2022
    Role: Principal Investigator
    A Psychiatric and Imaging Study of Pediatric Mild Traumatic Brain Injury
    NIH/NICHD R01HD068432Sep 1, 2011 - Jun 30, 2016
    Role: Principal Investigator
    SECONDARY ATTENTION DEFICIT HYPERACTIVITY DISORDER
    NIH/NIMH K08MH001800Dec 10, 1999 - May 31, 2005
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Bigler ED, Finuf C, Abildskov TJ, Goodrich-Hunsaker NJ, Petrie JA, Wood DM, Hesselink JR, Wilde EA, Max JE. Cortical thickness in pediatric mild traumatic brain injury including sports-related concussion. Int J Psychophysiol. 2018 Jul 21. PMID: 30040986.
      View in: PubMed
    2. Max JE. Jack Fell Down and Broke His Crown: Not Unusual and So Why the Skype? J Am Acad Child Adolesc Psychiatry. 2017 Nov; 56(11):916-917. PMID: 29096771.
      View in: PubMed
    3. Bigler ED, Abildskov TJ, Goodrich-Hunsaker NJ, Black G, Christensen ZP, Huff T, Wood DM, Hesselink JR, Wilde EA, Max JE. Structural Neuroimaging Findings in Mild Traumatic Brain Injury. Sports Med Arthrosc Rev. 2016 Sep; 24(3):e42-52. PMID: 27482782.
      View in: PubMed
    4. Sacchet MD, Ho TC, Connolly CG, Tymofiyeva O, Lewinn KZ, Han LK, Blom EH, Tapert SF, Max JE, Frank GK, Paulus MP, Simmons AN, Gotlib IH, Yang TT. Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder. Neuropsychopharmacology. 2016 11; 41(12):2951-2960. PMID: 27238621.
      View in: PubMed
    5. Emery CA, Barlow KM, Brooks BL, Max JE, Villavicencio-Requis A, Gnanakumar V, Robertson HL, Schneider K, Yeates KO. A Systematic Review of Psychiatric, Psychological, and Behavioural Outcomes following Mild Traumatic Brain Injury in Children and Adolescents. Can J Psychiatry. 2016 May; 61(5):259-69. PMID: 27254800; PMCID: PMC4841286 [Available on 11/01/16].
    6. Max JE. Concussion and Psychiatric Outcome in Adults and Children. Can J Psychiatry. 2016 May; 61(5):257-8. PMID: 27254799; PMCID: PMC4841288 [Available on 11/01/16].
    7. Max JE, Wilde EA, Bigler ED, Hanten G, Dennis M, Schachar RJ, Saunders AE, Ewing-Cobbs L, Chapman SB, Thompson WK, Yang TT, Levin HS. Personality Change Due to Traumatic Brain Injury in Children and Adolescents: Neurocognitive Correlates. J Neuropsychiatry Clin Neurosci. 2015; 27(4):272-9. PMID: 26185905; PMCID: PMC4618043.
    8. Max JE, Lopez A, Wilde EA, Bigler ED, Schachar RJ, Saunders A, Ewing-Cobbs L, Chapman SB, Yang TT, Levin HS. Anxiety disorders in children and adolescents in the second six months after traumatic brain injury. J Pediatr Rehabil Med. 2015; 8(4):345-55. PMID: 26684074.
      View in: PubMed
    9. Max JE, Friedman K, Wilde EA, Bigler ED, Hanten G, Schachar RJ, Saunders AE, Dennis M, Ewing-Cobbs L, Chapman SB, Yang TT, Levin HS. Psychiatric disorders in children and adolescents 24 months after mild traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2015; 27(2):112-20. PMID: 25923850; PMCID: PMC5007244.
    10. Ornstein TJ, Sagar S, Schachar RJ, Ewing-Cobbs L, Chapman SB, Dennis M, Saunders AE, Yang TT, Levin HS, Max JE. Neuropsychological performance of youth with secondary attention-deficit/hyperactivity disorder 6- and 12-months after traumatic brain injury. J Int Neuropsychol Soc. 2014 Nov; 20(10):971-81. PMID: 25489810; PMCID: PMC5010863.
    11. Ho TC, Connolly CG, Henje Blom E, LeWinn KZ, Strigo IA, Paulus MP, Frank G, Max JE, Wu J, Chan M, Tapert SF, Simmons AN, Yang TT. Emotion-Dependent Functional Connectivity of the Default Mode Network in Adolescent Depression. Biol Psychiatry. 2015 Nov 01; 78(9):635-46. PMID: 25483399; PMCID: PMC4362932 [Available on 11/01/16].
    12. Max JE. Neuropsychiatry of pediatric traumatic brain injury. Psychiatr Clin North Am. 2014 Mar; 37(1):125-40. PMID: 24529428; PMCID: PMC3977029.
    13. Ho TC, Yang G, Wu J, Cassey P, Brown SD, Hoang N, Chan M, Connolly CG, Henje-Blom E, Duncan LG, Chesney MA, Paulus MP, Max JE, Patel R, Simmons AN, Yang TT. Functional connectivity of negative emotional processing in adolescent depression. J Affect Disord. 2014 Feb; 155:65-74. PMID: 24268546; PMCID: PMC4961511.
    14. Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents. Biol Psychiatry. 2013 Dec 15; 74(12):898-907. PMID: 23910949; PMCID: PMC4103629.
    15. Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression. J Am Acad Child Adolesc Psychiatry. 2013 Oct; 52(10):1076-1091.e2. PMID: 24074474; PMCID: PMC3825460.
    16. Max JE, Schachar RJ, Landis J, Bigler ED, Wilde EA, Saunders AE, Ewing-Cobbs L, Chapman SB, Dennis M, Hanten G, Levin HS. Psychiatric disorders in children and adolescents in the first six months after mild traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2013; 25(3):187-97. PMID: 24026712.
      View in: PubMed
    17. Max JE, Pardo D, Hanten G, Schachar RJ, Saunders AE, Ewing-Cobbs L, Chapman SB, Dennis M, Wilde EA, Bigler ED, Thompson WK, Yang TT, Levin HS. Psychiatric disorders in children and adolescents six-to-twelve months after mild traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2013; 25(4):272-82. PMID: 24247854; PMCID: PMC5009904.
    18. Max JE, Wilde EA, Bigler ED, Thompson WK, MacLeod M, Vasquez AC, Merkley TL, Hunter JV, Chu ZD, Yallampalli R, Hotz G, Chapman SB, Yang TT, Levin HS. Neuroimaging correlates of novel psychiatric disorders after pediatric traumatic brain injury. J Am Acad Child Adolesc Psychiatry. 2012 Nov; 51(11):1208-17. PMID: 23101746; PMCID: PMC3511860.
    19. Ornstein TJ, Max JE, Schachar R, Dennis M, Barnes M, Ewing-Cobbs L, Levin HS. Response inhibition in children with and without ADHD after traumatic brain injury. J Neuropsychol. 2013 Mar; 7(1):1-11. PMID: 23464806; PMCID: PMC4439416.
    20. Perlman G, Simmons AN, Wu J, Hahn KS, Tapert SF, Max JE, Paulus MP, Brown GG, Frank GK, Campbell-Sills L, Yang TT. Amygdala response and functional connectivity during emotion regulation: a study of 14 depressed adolescents. J Affect Disord. 2012 Jun; 139(1):75-84. PMID: 22401827; PMCID: PMC3340443.
    21. Wilde EA, Merkley TL, Bigler ED, Max JE, Schmidt AT, Ayoub KW, McCauley SR, Hunter JV, Hanten G, Li X, Chu ZD, Levin HS. Longitudinal changes in cortical thickness in children after traumatic brain injury and their relation to behavioral regulation and emotional control. Int J Dev Neurosci. 2012 May; 30(3):267-76. PMID: 22266409; PMCID: PMC3322311.
    22. Max JE, Wilde EA, Bigler ED, MacLeod M, Vasquez AC, Schmidt AT, Chapman SB, Hotz G, Yang TT, Levin HS. Psychiatric disorders after pediatric traumatic brain injury: a prospective, longitudinal, controlled study. J Neuropsychiatry Clin Neurosci. 2012; 24(4):427-36. PMID: 23224448.
      View in: PubMed
    23. Max JE, Keatley E, Wilde EA, Bigler ED, Schachar RJ, Saunders AE, Ewing-Cobbs L, Chapman SB, Dennis M, Yang TT, Levin HS. Depression in children and adolescents in the first 6 months after traumatic brain injury. Int J Dev Neurosci. 2012 May; 30(3):239-45. PMID: 22197971; PMCID: PMC3322312.
    24. Max JE, Keatley E, Wilde EA, Bigler ED, Levin HS, Schachar RJ, Saunders A, Ewing-Cobbs L, Chapman SB, Dennis M, Yang TT. Anxiety disorders in children and adolescents in the first six months after traumatic brain injury. J Neuropsychiatry Clin Neurosci. 2011; 23(1):29-39. PMID: 21304136.
      View in: PubMed
    25. Yang TT, Simmons AN, Matthews SC, Tapert SF, Frank GK, Max JE, Bischoff-Grethe A, Lansing AE, Brown G, Strigo IA, Wu J, Paulus MP. Adolescents with major depression demonstrate increased amygdala activation. J Am Acad Child Adolesc Psychiatry. 2010 Jan; 49(1):42-51. PMID: 20215925; PMCID: PMC2935523.
    26. Max JE, Bruce M, Keatley E, Delis D. Pediatric stroke: plasticity, vulnerability, and age of lesion onset. J Neuropsychiatry Clin Neurosci. 2010; 22(1):30-9. PMID: 20160207.
      View in: PubMed
    27. Ornstein TJ, Levin HS, Chen S, Hanten G, Ewing-Cobbs L, Dennis M, Barnes M, Max JE, Logan GD, Schachar R. Performance monitoring in children following traumatic brain injury. J Child Psychol Psychiatry. 2009 Apr; 50(4):506-13. PMID: 19207625.
      View in: PubMed
    28. Levin HS, Hanten G, Roberson G, Li X, Ewing-Cobbs L, Dennis M, Chapman S, Max JE, Hunter J, Schachar R, Luerssen TG, Swank P. Prediction of cognitive sequelae based on abnormal computed tomography findings in children following mild traumatic brain injury. J Neurosurg Pediatr. 2008 Jun; 1(6):461-70. PMID: 18518697.
      View in: PubMed
    29. Levin H, Hanten G, Max J, Li X, Swank P, Ewing-Cobbs L, Dennis M, Menefee DS, Schachar R. Symptoms of attention-deficit/hyperactivity disorder following traumatic brain injury in children. J Dev Behav Pediatr. 2007 Apr; 28(2):108-18. PMID: 17435461.
      View in: PubMed
    30. Max JE, Levin HS, Schachar RJ, Landis J, Saunders AE, Ewing-Cobbs L, Chapman SB, Dennis M. Predictors of personality change due to traumatic brain injury in children and adolescents six to twenty-four months after injury. J Neuropsychiatry Clin Neurosci. 2006; 18(1):21-32. PMID: 16525067.
      View in: PubMed
    31. Max JE, Schachar RJ, Levin HS, Ewing-Cobbs L, Chapman SB, Dennis M, Saunders A, Landis J. Predictors of attention-deficit/hyperactivity disorder within 6 months after pediatric traumatic brain injury. J Am Acad Child Adolesc Psychiatry. 2005 Oct; 44(10):1032-40. PMID: 16175108.
      View in: PubMed
    32. Max JE, Schachar RJ, Levin HS, Ewing-Cobbs L, Chapman SB, Dennis M, Saunders A, Landis J. Predictors of secondary attention-deficit/hyperactivity disorder in children and adolescents 6 to 24 months after traumatic brain injury. J Am Acad Child Adolesc Psychiatry. 2005 Oct; 44(10):1041-9. PMID: 16175109.
      View in: PubMed
    33. Max JE, Manes FF, Robertson BA, Mathews K, Fox PT, Lancaster J. Prefrontal and executive attention network lesions and the development of attention-deficit/hyperactivity symptomatology. J Am Acad Child Adolesc Psychiatry. 2005 May; 44(5):443-50. PMID: 15843766.
      View in: PubMed
    34. Max JE, Levin HS, Landis J, Schachar R, Saunders A, Ewing-Cobbs L, Chapman SB, Dennis M. Predictors of personality change due to traumatic brain injury in children and adolescents in the first six months after injury. J Am Acad Child Adolesc Psychiatry. 2005 May; 44(5):434-42. PMID: 15843765.
      View in: PubMed
    35. Mosch SC, Max JE, Tranel D. A matched lesion analysis of childhood versus adult-onset brain injury due to unilateral stroke: another perspective on neural plasticity and recovery of social functioning. Cogn Behav Neurol. 2005 Mar; 18(1):5-17. PMID: 15761272.
      View in: PubMed
    36. Leblanc N, Chen S, Swank PR, Ewing-Cobbs L, Barnes M, Dennis M, Max J, Levin H, Schachar R. Response inhibition after traumatic brain injury (TBI) in children: impairment and recovery. Dev Neuropsychol. 2005; 28(3):829-48. PMID: 16266251.
      View in: PubMed
    37. Max JE, Robin DA, Taylor HG, Yeates KO, Fox PT, Lancaster JL, Manes FF, Mathews K, Austermann S. Attention function after childhood stroke. J Int Neuropsychol Soc. 2004 Nov; 10(7):976-86. PMID: 15803561.
      View in: PubMed
    38. Max JE. Effect of side of lesion on neuropsychological performance in childhood stroke. J Int Neuropsychol Soc. 2004 Sep; 10(5):698-708. PMID: 15327717.
      View in: PubMed
    39. Lansing AE, Max JE, Delis DC, Fox PT, Lancaster J, Manes FF, Schatz A. Verbal learning and memory after childhood stroke. J Int Neuropsychol Soc. 2004 Sep; 10(5):742-52. PMID: 15327721.
      View in: PubMed
    40. Wassenberg R, Max JE, Lindgren SD, Schatz A. Sustained attention in children and adolescents after traumatic brain injury: relation to severity of injury, adaptive functioning, ADHD and social background. Brain Inj. 2004 Aug; 18(8):751-64. PMID: 15204316.
      View in: PubMed
    41. Levin HS, Zhang L, Dennis M, Ewing-Cobbs L, Schachar R, Max J, Landis JA, Roberson G, Scheibel RS, Miller DL, Hunter JV. Psychosocial outcome of TBI in children with unilateral frontal lesions. J Int Neuropsychol Soc. 2004 May; 10(3):305-16. PMID: 15147589.
      View in: PubMed
    42. Wassenberg R, Max JE, Koele SL, Firme K. Classifying psychiatric disorders after traumatic brain injury and orthopaedic injury in children: adequacy of K-SADS versus CBCL. Brain Inj. 2004 Apr; 18(4):377-90. PMID: 14742151.
      View in: PubMed
    43. Levin HS, Hanten G, Zhang L, Swank PR, Ewing-Cobbs L, Dennis M, Barnes MA, Max J, Schachar R, Chapman SB, Hunter JV. Changes in working memory after traumatic brain injury in children. Neuropsychology. 2004 Apr; 18(2):240-7. PMID: 15099146.
      View in: PubMed
    44. Schachar R, Levin HS, Max JE, Purvis K, Chen S. Attention deficit hyperactivity disorder symptoms and response inhibition after closed head injury in children: do preinjury behavior and injury severity predict outcome? Dev Neuropsychol. 2004; 25(1-2):179-98. PMID: 14984334.
      View in: PubMed
    45. Max JE, Lansing AE, Koele SL, Castillo CS, Bokura H, Schachar R, Collings N, Williams KE. Attention deficit hyperactivity disorder in children and adolescents following traumatic brain injury. Dev Neuropsychol. 2004; 25(1-2):159-77. PMID: 14984333.
      View in: PubMed
    46. Max JE, Mathews K, Manes FF, Robertson BA, Fox PT, Lancaster JL, Lansing AE, Schatz A, Collings N. Attention deficit hyperactivity disorder and neurocognitive correlates after childhood stroke. J Int Neuropsychol Soc. 2003 Sep; 9(6):815-29. PMID: 14632240.
      View in: PubMed
    47. Chapman SB, Max JE, Gamino JF, McGlothlin JH, Cliff SN. Discourse plasticity in children after stroke: age at injury and lesion effects. Pediatr Neurol. 2003 Jul; 29(1):34-41. PMID: 13679119.
      View in: PubMed
    48. Levin HS, Hanten G, Chang CC, Zhang L, Schachar R, Ewing-Cobbs L, Max JE. Working memory after traumatic brain injury in children. Ann Neurol. 2002 Jul; 52(1):82-8. PMID: 12112051.
      View in: PubMed
    49. Max JE, Mathews K, Lansing AE, Robertson BA, Fox PT, Lancaster JL, Manes FF, Smith J. Psychiatric disorders after childhood stroke. J Am Acad Child Adolesc Psychiatry. 2002 May; 41(5):555-62. PMID: 12014788.
      View in: PubMed
    50. Max JE, Fox PT, Lancaster JL, Kochunov P, Mathews K, Manes FF, Robertson BA, Arndt S, Robin DA, Lansing AE. Putamen lesions and the development of attention-deficit/hyperactivity symptomatology. J Am Acad Child Adolesc Psychiatry. 2002 May; 41(5):563-71. PMID: 12014789.
      View in: PubMed
    51. Max JE, Koele SL, Castillo CC, Lindgren SD, Arndt S, Bokura H, Robin DA, Smith WL, Sato Y. Personality change disorder in children and adolescents following traumatic brain injury. J Int Neuropsychol Soc. 2000 Mar; 6(3):279-89. PMID: 10824500.
      View in: PubMed