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Marc Schuckit

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentPsychiatry
Address9500 Gilman Drive #0866
La Jolla CA 92093
Phone858-822-0880
vCardDownload vCard

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    Biography

    Dr. Schuckit received a B.S. from the University of Wisconsin, an M.D. from Washington University, interned at Cedars Sinai Medical Center, and was a resident in psychiatry at Washington University and UCSD. He was a special advisor to the Commanding Officer of the Naval Health Research Center (1972–1974), and the first Director of the Alcohol and Drug Institute, University of Washington (1975–1978). He returned to San Diego in 1978 as Director of the Alcohol and Drug Treatment Program, University of California, San Diego, and the VA San Diego Healthcare System, which he directed until July 1, 2009. His research focuses on genetic and environmental influences in alcohol and drug use disorders, comorbid psychiatric conditions in the context of alcohol and drug use, and diagnostic systems related to these conditions. Dr. Schuckit’s recent projects include increasing the understanding of the biologic underpinnings of the low sensitivity to alcohol through functional brain imaging techniques, and implementing a program to decrease heavy drinking in adolescents by teaching them about genetically influenced characteristics they carry that increase their risks for alcohol-related problems.

    Research Interests

    Dr. Schuckit’s major focus is alcohol and drugs. He was Chair of the DSM-IV substance disorders workgroup and a member of the DSM-V committee. In addition, he has published papers about the optimal diagnostic criteria for substance use disorders. Regarding the genetics of alcoholism, Dr. Schuckit has carried out adoption-type studies, identified a genetic characteristic that impacts on elevated alcoholism risk (the low level of response to alcohol), and is now uncovering related genes. He is currently completing a 25-year follow-up (94% success rate) of sons of alcoholics where he is identifying environmental events that might relate to how the biological predisposition toward alcohol dependence is mediated. An additional research area is co-morbidity between substance use disorders and major psychiatric conditions.

    Clinical Focus

    Dr. Schuckit directed the Alcohol and Drug Treatment Program at the VA San Diego Healthcare System, and still supervises residents, medical students, and staff. He is also a major contact person regarding alcohol and drug problems in students, faculty, and staff at UCSD and the San Diego VA. Additional clinical interests include the treatment of depressive disorders, anxiety conditions, and geriatric psychiatric populations.


    Collapse Research 
    Collapse Research Activities and Funding
    Using Placebo and Alcohol Session fMRI to Predict Adverse Alcohol Outcomes
    NIH/NIAAA R21AA021827Jul 1, 2013 - Jun 30, 2015
    Role: Principal Investigator
    PREVENTION APPROACH TO COLLEGE HEAVY DRINKING BASED ON A LOW RESPONSE TO ALCOHOL
    NIH/NIAAA R01AA021162Feb 1, 2013 - Jan 31, 2015
    Role: Principal Investigator
    LEVEL OF RESPONSE TO ALCOHOL AND BRAIN FUNCTIONING
    NIH/NIAAA R01AA015760Aug 15, 2006 - Jun 30, 2012
    Role: Principal Investigator
    Collaborative Study on the Genetics of Alcoholism (COGA)
    NIH U10AA008401Sep 29, 1989 - Aug 31, 2019
    Role: Co-Investigator
    Prospective Study: Alcoholic &Control Family Offspring
    NIH/NIAAA R01AA005526Sep 29, 1982 - Jun 30, 2011
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Schuckit M. A Critical Review of Methods and Results in the Search for Genetic Contributors to Alcohol Sensitivity. Alcohol Clin Exp Res. 2018 May; 42(5):822-835. PMID: 29623680.
      View in: PubMed
    2. Schuckit M, Smith TL. Mediation of effects of the level of response to alcohol and impulsivity 15 years later in 36-year-old men: Implications for prevention efforts. Drug Alcohol Depend. 2017 Nov 01; 180:356-362. PMID: 28954250.
      View in: PubMed
    3. McCutcheon VV, Agrawal A, Kuo SI, Su J, Dick DM, Meyers JL, Edenberg HJ, Nurnberger JI, Kramer JR, Kuperman S, Schuckit M, Hesselbrock VM, Brooks A, Porjesz B, Bucholz KK. Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families. Addiction. 2018 Feb; 113(2):336-345. PMID: 28804966.
      View in: PubMed
    4. Schuckit M. Remarkable Increases in Alcohol Use Disorders. JAMA Psychiatry. 2017 Sep 01; 74(9):869-870. PMID: 28793142.
      View in: PubMed
    5. Gonçalves PD, Smith TL, Anthenelli RM, Danko G, Schuckit M. Alcohol-related blackouts among college students: impact of low level of response to alcohol, ethnicity, sex, and environmental characteristics. Rev Bras Psiquiatr. 2017 Aug 31; 0. PMID: 28876407.
      View in: PubMed
    6. McCutcheon VV, Schuckit M, Kramer JR, Chan G, Edenberg HJ, Smith TL, Bender AK, Hesselbrock V, Hesselbrock M, Bucholz KK. Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands. Addiction. 2017 Nov; 112(11):1909-1917. PMID: 28556494.
      View in: PubMed
    7. Gonçalves PD, Schuckit M, Smith TL. Drinking Status Between Ages 50 and 55 for Men From the San Diego Prospective Study Who Developed DSM-IV Alcohol Abuse or Dependence in Prior Follow-Ups. J Stud Alcohol Drugs. 2017 Jul; 78(4):512-520. PMID: 28728633.
      View in: PubMed
    8. Schuckit M, Smith TL, Danko G, Anthenelli R, Schoen L, Kawamura M, Kramer J, Dick DM, Neale Z, Kuperman S, McCutcheon V, Anokhin AP, Hesselbrock V, Hesselbrock M, Bucholz K. A Prospective Comparison of How the Level of Response to Alcohol and Impulsivity Relate to Future DSM-IV Alcohol Problems in the COGA Youth Panel. Alcohol Clin Exp Res. 2017 Jul; 41(7):1329-1339. PMID: 28440866.
      View in: PubMed
    9. Schuckit M. Letter to the Editor of JSAD Regarding the INEBRIA Position Statement. J Stud Alcohol Drugs. 2017 Mar; 78(2):331-332. PMID: 28317517.
      View in: PubMed
    10. Agrawal A, Tillman R, Grucza RA, Nelson EC, McCutcheon VV, Few L, Conner KR, Lynskey MT, Dick DM, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI, Schuckit M, Porjesz B, Bucholz KK. Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism. J Affect Disord. 2017 04 15; 213:96-104. PMID: 28213124.
      View in: PubMed
    11. Bucholz KK, McCutcheon VV, Agrawal A, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Nurnberger JI, Salvatore JE, Schuckit M, Bierut LJ, Foroud TM, Chan G, Hesselbrock M, Meyers JL, Edenberg HJ, Porjesz B. Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study. Alcohol Clin Exp Res. 2017 Feb; 41(2):359-368. PMID: 28073157.
      View in: PubMed
    12. Schuckit M, Smith TL, Shafir A, Clausen P, Danko G, Gonçalves PD, Anthenelli RM, Chan G, Kuperman S, Hesselbrock M, Hesselbrock V, Kramer J, Bucholz KK. Predictors of Patterns of Alcohol-Related Blackouts Over Time in Youth From the Collaborative Study of the Genetics of Alcoholism: The Roles of Genetics and Cannabis. J Stud Alcohol Drugs. 2017 Jan; 78(1):39-48. PMID: 27936363.
      View in: PubMed
    13. Olfson E, Bloom J, Bertelsen S, Budde JP, Breslau N, Brooks A, Culverhouse R, Chan G, Chen LS, Chorlian D, Dick DM, Edenberg HJ, Hartz S, Hatsukami D, Hesselbrock VM, Johnson EO, Kramer JR, Kuperman S, Meyers JL, Nurnberger J, Porjesz B, Saccone NL, Schuckit M, Stitzel J, Tischfield JA, Rice JP, Goate A, Bierut LJ. CYP2A6 metabolism in the development of smoking behaviors in young adults. Addict Biol. 2018 Jan; 23(1):437-447. PMID: 28032407.
      View in: PubMed
    14. Schuckit M, Smith TL, Goncalves PD, Anthenelli R. Alcohol-related blackouts across 55 weeks of college: Effects of European-American ethnicity, female sex, and low level of response to alcohol. Drug Alcohol Depend. 2016 12 01; 169:163-170. PMID: 27835824.
      View in: PubMed
    15. Schuckit M. Treatment of Opioid-Use Disorders. N Engl J Med. 2016 10 20; 375(16):1596-1597. PMID: 27797302.
      View in: PubMed
    16. Schuckit M. Treatment of Opioid-Use Disorders. N Engl J Med. 2016 Jul 28; 375(4):357-68. PMID: 27464203.
      View in: PubMed
    17. Chartier KG, Dick DM, Almasy L, Chan G, Aliev F, Schuckit M, Scott DM, Kramer J, Bucholz KK, Bierut LJ, Nurnberger J, Porjesz B, Hesselbrock VM. Interactions Between Alcohol Metabolism Genes and Religious Involvement in Association With Maximum Drinks and Alcohol Dependence Symptoms. J Stud Alcohol Drugs. 2016 05; 77(3):393-404. PMID: 27172571; PMCID: PMC4869897 [Available on 05/01/17].
    18. Schuckit M, Smith TL, Clausen P, Skidmore J, Shafir A, Kalmijn J. Drinking Patterns Across Spring, Summer, and Fall in 462 University Students. Alcohol Clin Exp Res. 2016 Apr; 40(4):889-96. PMID: 27038597; PMCID: PMC4819255 [Available on 04/01/17].
    19. Schuckit M, Smith TL, Paulus MP, Tapert SF, Simmons AN, Tolentino NJ, Shafir A. The Ability of Functional Magnetic Resonance Imaging to Predict Heavy Drinking and Alcohol Problems 5 Years Later. Alcohol Clin Exp Res. 2016 Jan; 40(1):206-13. PMID: 26727535; PMCID: PMC4700546 [Available on 01/01/17].
    20. Schuckit M, Smith TL, Clausen P, Fromme K, Skidmore J, Shafir A, Kalmijn J. The Low Level of Response to Alcohol-Based Heavy Drinking Prevention Program: One-Year Follow-Up. J Stud Alcohol Drugs. 2016 Jan; 77(1):25-37. PMID: 26751352; PMCID: PMC4711317 [Available on 01/01/17].
    21. Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Anokhin AP, Bauer LO, Kuperman S, Kramer J, Bucholz KK, Schuckit M, Hesselbrock VM, Porjesz B. Deficient Event-Related Theta Oscillations in Individuals at Risk for Alcoholism: A Study of Reward Processing and Impulsivity Features. PLoS One. 2015; 10(11):e0142659. PMID: 26580209.
      View in: PubMed
    22. Savage JE, Neale Z, Cho SB, Hancock L, Kalmijn JA, Smith TL, Schuckit M, Donovan KK, Dick DM. Level of response to alcohol as a factor for targeted prevention in college students. Alcohol Clin Exp Res. 2015 Nov; 39(11):2215-23. PMID: 26503068; PMCID: PMC4624230 [Available on 11/01/16].
    23. Kamarajan C, Pandey AK, Chorlian DB, Manz N, Stimus AT, Bauer LO, Hesselbrock VM, Schuckit M, Kuperman S, Kramer J, Porjesz B. Reward processing deficits and impulsivity in high-risk offspring of alcoholics: A study of event-related potentials during a monetary gambling task. Int J Psychophysiol. 2015 Nov; 98(2 Pt 1):182-200. PMID: 26388585; PMCID: PMC4898464.
    24. Schuckit M. Editor's Corner: Thank You for My Wonderful Years With the Journal of Studies on Alcohol and Drugs. J Stud Alcohol Drugs. 2015 May; 76(3):353-4. PMID: 25978819.
      View in: PubMed
    25. Salvatore JE, Aliev F, Bucholz K, Agrawal A, Hesselbrock V, Hesselbrock M, Bauer L, Kuperman S, Schuckit M, Kramer J, Edenberg HJ, Foroud TM, Dick DM. Polygenic risk for externalizing disorders: Gene-by-development and gene-by-environment effects in adolescents and young adults. Clin Psychol Sci. 2015 Mar; 3(2):189-201. PMID: 25821660.
      View in: PubMed
    26. Schuckit M, Smith TL, Kalmijn J, Skidmore J, Clausen P, Shafir A, Saunders G, Bystritsky H, Fromme K. The impact of focusing a program to prevent heavier drinking on a pre-existing phenotype, the low level of response to alcohol. Alcohol Clin Exp Res. 2015 Feb; 39(2):308-16. PMID: 25656349; PMCID: PMC4331238.
    27. Schuckit M. Management of withdrawal delirium (delirium tremens). N Engl J Med. 2015 02 05; 372(6):580-1. PMID: 25651262.
      View in: PubMed
    28. Schuckit M, Smith TL, Heron J, Hickman M, Macleod J, Munafo MR, Kendler KS, Dick DM, Davey-Smith G. Latent trajectory classes for alcohol-related blackouts from age 15 to 19 in ALSPAC. Alcohol Clin Exp Res. 2015 Jan; 39(1):108-16. PMID: 25516068.
      View in: PubMed
    29. Schuckit M. Nancy Kishlar Mello. Neuropsychopharmacology. 2014 Dec; 39(13):3129-30. PMID: 25381707; PMCID: PMC4229589.
    30. Schuckit M. Recognition and management of withdrawal delirium (delirium tremens). N Engl J Med. 2014 Nov 27; 371(22):2109-13. PMID: 25427113.
      View in: PubMed
    31. Olfson E, Edenberg HJ, Nurnberger J, Agrawal A, Bucholz KK, Almasy LA, Chorlian D, Dick DM, Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, Schuckit M, Tischfield JA, Wang JC, Wetherill L, Foroud TM, Rice J, Goate A, Bierut LJ. An ADH1B variant and peer drinking in progression to adolescent drinking milestones: evidence of a gene-by-environment interaction. Alcohol Clin Exp Res. 2014 Oct; 38(10):2541-9. PMID: 25257461; PMCID: PMC4256939.
    32. McCutcheon VV, Kramer JR, Edenberg HJ, Nurnberger JI, Kuperman S, Schuckit M, Heath AC, Bucholz KK. Social contexts of remission from DSM-5 alcohol use disorder in a high-risk sample. Alcohol Clin Exp Res. 2014 Jul; 38(7):2015-23. PMID: 24942361; PMCID: PMC4107016.
    33. Schuckit M. The answer you get depends on the question you ask. Biol Psychiatry. 2014 May 15; 75(10):754-5. PMID: 24780011.
      View in: PubMed
    34. Schuckit M. In memoriam: Remembering Professor Roger Nordmann, May 24, 1926-January 24, 2014. J Stud Alcohol Drugs. 2014 May; 75(3):377. PMID: 24766748.
      View in: PubMed
    35. Culverhouse RC, Johnson EO, Breslau N, Hatsukami DK, Sadler B, Brooks AI, Hesselbrock VM, Schuckit M, Tischfield JA, Goate AM, Saccone NL, Bierut LJ. Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans. Addiction. 2014 May; 109(5):814-22. PMID: 24401102.
      View in: PubMed
    36. Schuckit M. A brief history of research on the genetics of alcohol and other drug use disorders. J Stud Alcohol Drugs Suppl. 2014; 75 Suppl 17:59-67. PMID: 24565312; PMCID: PMC4453498.
    37. Schuckit M. A tribute to Nancy Kishlar Mello. J Stud Alcohol Drugs. 2014 Jan; 75(1):191-2. PMID: 24411812.
      View in: PubMed
    38. Schuckit M, Smith TL, Danko GP, Bucholz KK, Agrawal A, Dick DM, Nurnberger JI, Kramer J, Hesselbrock M, Saunders G, Hesselbrock V. Predictors of subgroups based on maximum drinks per occasion over six years for 833 adolescents and young adults in COGA. J Stud Alcohol Drugs. 2014 Jan; 75(1):24-34. PMID: 24411794; PMCID: PMC3893632.
    39. Hashimoto E, Riederer PF, Hesselbrock VM, Hesselbrock MN, Mann K, Ukai W, Sohma H, Thibaut F, Schuckit M, Saito T. Consensus paper of the WFSBP task force on biological markers: biological markers for alcoholism. World J Biol Psychiatry. 2013 Dec; 14(8):549-64. PMID: 24236956.
      View in: PubMed
    40. Schuckit M. Editor's corner: DSM-5--ready or not, here it comes. J Stud Alcohol Drugs. 2013 Sep; 74(5):661-3. PMID: 23948524.
      View in: PubMed
    41. Schuckit M, Smith TL, Kalmijn JA. The patterns of drug and alcohol use and associated problems over 30 years in 397 men. Alcohol Clin Exp Res. 2014 Jan; 38(1):227-34. PMID: 23895676; PMCID: PMC3830655.
    42. Zhang Z, Wang JC, Howells W, Lin P, Agrawal A, Edenberg HJ, Tischfield JA, Schuckit M, Bierut LJ, Goate A, Rice JP. Dosage transmission disequilibrium test (dTDT) for linkage and association detection. PLoS One. 2013; 8(5):e63526. PMID: 23691058; PMCID: PMC3653954.
    43. Trim RS, Schuckit M, Smith TL. Predictors of initial and sustained remission from alcohol use disorders: findings from the 30-year follow-up of the San Diego Prospective Study. Alcohol Clin Exp Res. 2013 Aug; 37(8):1424-31. PMID: 23458300; PMCID: PMC3675188.
    44. Choquet H, Joslyn G, Lee A, Kasberger J, Robertson M, Brush G, Schuckit M, White R, Jorgenson E. Examination of rare missense variants in the CHRNA5-A3-B4 gene cluster to level of response to alcohol in the San Diego Sibling Pair study. Alcohol Clin Exp Res. 2013 Aug; 37(8):1311-6. PMID: 23458267.
      View in: PubMed
    45. Schuckit M, Smith TL, Kalmijn J. Relationships among independent major depressions, alcohol use, and other substance use and related problems over 30 years in 397 families. J Stud Alcohol Drugs. 2013 Mar; 74(2):271-9. PMID: 23384375; PMCID: PMC3568166.
    46. Yan J, Aliev F, Webb BT, Kendler KS, Williamson VS, Edenberg HJ, Agrawal A, Kos MZ, Almasy L, Nurnberger JI, Schuckit M, Kramer JR, Rice JP, Kuperman S, Goate AM, Tischfield JA, Porjesz B, Dick DM. Using genetic information from candidate gene and genome-wide association studies in risk prediction for alcohol dependence. Addict Biol. 2014 Jul; 19(4):708-21. PMID: 23362995; PMCID: PMC3664249.
    47. Zhao Z, Guo AY, van den Oord EJ, Aliev F, Jia P, Edenberg HJ, Riley BP, Dick DM, Bettinger JC, Davies AG, Grotewiel MS, Schuckit M, Agrawal A, Kramer J, Nurnberger JI, Kendler KS, Webb BT, Miles MF. Multi-species data integration and gene ranking enrich significant results in an alcoholism genome-wide association study. BMC Genomics. 2012; 13 Suppl 8:S16. PMID: 23282140; PMCID: PMC3535715.
    48. Schuckit M, Smith TL. Stability of scores and correlations with drinking behaviors over 15 years for the Self-Report of the Effects of Alcohol Questionnaire. Drug Alcohol Depend. 2013 Mar 01; 128(3):194-9. PMID: 22980675; PMCID: PMC3537846.
    49. Schuckit M. Editor's corner: editorial in reply to the comments of Griffith Edwards. J Stud Alcohol Drugs. 2012 Jul; 73(4):521-2. PMID: 22630789.
      View in: PubMed
    50. Schuckit M. Commentary on 'reduced subjective response to acute ethanol administration among young men with a broad bipolar phenotype'. Neuropsychopharmacology. 2012 Jul; 37(8):1797-8. PMID: 22699687; PMCID: PMC3376331.
    51. Schuckit M, Smith TL, Trim RS, Kuperman S, Kramer J, Hesselbrock V, Bucholz KK, Nurnberger JI, Hesselbrock M, Saunders G. Sex differences in how a low sensitivity to alcohol relates to later heavy drinking. Drug Alcohol Rev. 2012 Nov; 31(7):871-80. PMID: 22708705; PMCID: PMC3459074.
    52. Lin P, Hartz SM, Wang JC, Agrawal A, Zhang TX, McKenna N, Bucholz K, Brooks AI, Tischfield JA, Edenberg HJ, Hesselbrock VM, Kramer JR, Kuperman S, Schuckit M, Goate AM, Bierut LJ, Rice JP. Copy number variations in 6q14.1 and 5q13.2 are associated with alcohol dependence. Alcohol Clin Exp Res. 2012 Sep; 36(9):1512-8. PMID: 22702843; PMCID: PMC3436997.
    53. Paulus MP, Schuckit M, Tapert SF, Tolentino NJ, Matthews SC, Smith TL, Trim RS, Hall SA, Simmons AN. High versus low level of response to alcohol: evidence of differential reactivity to emotional stimuli. Biol Psychiatry. 2012 Nov 15; 72(10):848-55. PMID: 22608014; PMCID: PMC3433640.
    54. Schuckit M, Smith TL, Kalmijn J, Trim RS, Cesario E, Saunders G, Sanchez C, Campbell N. Comparison across two generations of prospective models of how the low level of response to alcohol affects alcohol outcomes. J Stud Alcohol Drugs. 2012 Mar; 73(2):195-204. PMID: 22333327; PMCID: PMC3281979.
    55. Schuckit M, Kalmijn JA, Smith TL, Saunders G, Fromme K. Structuring a college alcohol prevention program on the low level of response to alcohol model: a pilot study. Alcohol Clin Exp Res. 2012 Jul; 36(7):1244-52. PMID: 22309202.
      View in: PubMed
    56. Edwards AC, Aliev F, Bierut LJ, Bucholz KK, Edenberg H, Hesselbrock V, Kramer J, Kuperman S, Nurnberger JI, Schuckit M, Porjesz B, Dick DM. Genome-wide association study of comorbid depressive syndrome and alcohol dependence. Psychiatr Genet. 2012 Feb; 22(1):31-41. PMID: 22064162; PMCID: PMC3241912.
    57. Schuckit M. The history of our field: reflections on the solid foundations on which we stand--the contributions of Griffith Edwards. J Stud Alcohol Drugs. 2012 Jan; 73(1):6-9. PMID: 22152655.
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    58. Schuckit M. Editor's corner: the family is changing. J Stud Alcohol Drugs. 2012 Jan; 73(1):5. PMID: 22152654.
      View in: PubMed
    59. Schuckit M, Tapert S, Matthews SC, Paulus MP, Tolentino NJ, Smith TL, Trim RS, Hall S, Simmons A. fMRI differences between subjects with low and high responses to alcohol during a stop signal task. Alcohol Clin Exp Res. 2012 01; 36(1):130-40. PMID: 22003983; PMCID: PMC3253183.
    60. Schuckit M, Smith TL, Trim RS, Allen RC, Fukukura T, Knight EE, Cesario EM, Kreikebaum SA. A prospective evaluation of how a low level of response to alcohol predicts later heavy drinking and alcohol problems. Am J Drug Alcohol Abuse. 2011 Nov; 37(6):479-86. PMID: 21797810.
      View in: PubMed
    61. Lasek AW, Lim J, Kliethermes CL, Berger KH, Joslyn G, Brush G, Xue L, Robertson M, Moore MS, Vranizan K, Morris SW, Schuckit M, White RL, Heberlein U. An evolutionary conserved role for anaplastic lymphoma kinase in behavioral responses to ethanol. PLoS One. 2011; 6(7):e22636. PMID: 21799923.
      View in: PubMed
    62. Schuckit M, Smith TL, Heron J, Hickman M, Macleod J, Lewis G, Davis JM, Hibbeln JR, Brown S, Zuccolo L, Miller LL, Davey-Smith G. Testing a level of response to alcohol-based model of heavy drinking and alcohol problems in 1,905 17-year-olds. Alcohol Clin Exp Res. 2011 Oct; 35(10):1897-904. PMID: 21762180.
      View in: PubMed
    63. Neufeld KJ, Schuckit M, Hernandez-Avila CA. Alcohol medical scholars program--a mentorship program for improving medical education regarding substance use disorders. Subst Abus. 2011 Jul; 32(3):121-7. PMID: 21660871.
      View in: PubMed
    64. Padula CB, Simmons AN, Matthews SC, Robinson SK, Tapert SF, Schuckit M, Paulus MP. Alcohol attenuates activation in the bilateral anterior insula during an emotional processing task: a pilot study. Alcohol Alcohol. 2011 Sep-Oct; 46(5):547-52. PMID: 21665869; PMCID: PMC3201697.
    65. Schuckit M. Comment on the paper by Quinn and Fromme entitled subjective response to alcohol challenge: a quantitative review. Alcohol Clin Exp Res. 2011 Oct; 35(10):1723-5. PMID: 21651583.
      View in: PubMed
    66. McCutcheon VV, Agrawal A, Heath AC, Edenberg HJ, Hesselbrock VM, Schuckit M, Kramer JR, Bucholz KK. Functioning of alcohol use disorder criteria among men and women with arrests for driving under the influence of alcohol. Alcohol Clin Exp Res. 2011 Nov; 35(11):1985-93. PMID: 21631541; PMCID: PMC3166544.
    67. Johnson BA, Messing RO, Charness ME, Crabbe JC, Goldman MS, Harris RA, Kranzler HR, Mitchell MC, Nixon SJ, Riley EP, Schuckit M, Sher KJ, Thomas JD. How Should Addiction-Related Research at the National Institutes of Health be Reorganized? Front Psychiatry. 2011; 2:2. PMID: 21629835; PMCID: PMC3098615.
    68. Johnson BA, Messing RO, Charness ME, Crabbe JC, Goldman MS, Harris RA, Kranzler HR, Mitchell MC, Nixon SJ, Riley EP, Schuckit M, Sher KJ, Thomas JD. Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details. Alcohol Clin Exp Res. 2011 Apr; 35(4):572-80. PMID: 21443646; PMCID: PMC3068603.
    69. Tolentino NJ, Wierenga CE, Hall S, Tapert SF, Paulus MP, Liu TT, Smith TL, Schuckit M. Alcohol effects on cerebral blood flow in subjects with low and high responses to alcohol. Alcohol Clin Exp Res. 2011 Jun; 35(6):1034-40. PMID: 21332525; PMCID: PMC3097275.
    70. Zlojutro M, Manz N, Rangaswamy M, Xuei X, Flury-Wetherill L, Koller D, Bierut LJ, Goate A, Hesselbrock V, Kuperman S, Nurnberger J, Rice JP, Schuckit M, Foroud T, Edenberg HJ, Porjesz B, Almasy L. Genome-wide association study of theta band event-related oscillations identifies serotonin receptor gene HTR7 influencing risk of alcohol dependence. Am J Med Genet B Neuropsychiatr Genet. 2011 Jan; 156B(1):44-58. PMID: 21184583; PMCID: PMC3139811.
    71. Webb A, Lind PA, Kalmijn J, Feiler HS, Smith TL, Schuckit M, Wilhelmsen K. The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis. Alcohol Clin Exp Res. 2011 Jan; 35(1):10-8. PMID: 20958328; PMCID: PMC3005010.
    72. Ehlers CL, Gizer IR, Schuckit M, Wilhelmsen KC. Genome-wide scan for self-rating of the effects of alcohol in American Indians. Psychiatr Genet. 2010 Oct; 20(5):221-8. PMID: 20505555; PMCID: PMC2933945.
    73. Derringer J, Krueger RF, Dick DM, Saccone S, Grucza RA, Agrawal A, Lin P, Almasy L, Edenberg HJ, Foroud T, Nurnberger JI, Hesselbrock VM, Kramer JR, Kuperman S, Porjesz B, Schuckit M, Bierut LJ. Predicting sensation seeking from dopamine genes. A candidate-system approach. Psychol Sci. 2010 Sep; 21(9):1282-90. PMID: 20732903.
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    74. Schuckit M, Smith TL. Onset and course of alcoholism over 25 years in middle class men. Drug Alcohol Depend. 2011 Jan 01; 113(1):21-8. PMID: 20727682; PMCID: PMC3000869.
    75. Trim RS, Simmons AN, Tolentino NJ, Hall SA, Matthews SC, Robinson SK, Smith TL, Padula CB, Paulus MP, Tapert SF, Schuckit M. Acute ethanol effects on brain activation in low- and high-level responders to alcohol. Alcohol Clin Exp Res. 2010 Jul; 34(7):1162-70. PMID: 20477775; PMCID: PMC3774836.
    76. Chen AC, Manz N, Tang Y, Rangaswamy M, Almasy L, Kuperman S, Nurnberger J, O'Connor SJ, Edenberg HJ, Schuckit M, Tischfield J, Foroud T, Bierut LJ, Rohrbaugh J, Rice JP, Goate A, Hesselbrock V, Porjesz B. Single-nucleotide polymorphisms in corticotropin releasing hormone receptor 1 gene (CRHR1) are associated with quantitative trait of event-related potential and alcohol dependence. Alcohol Clin Exp Res. 2010 Jun; 34(6):988-96. PMID: 20374216; PMCID: PMC3248053.
    77. Schuckit M, Smith TL, Trim RS, Tolentino NJ, Hall SA. Comparing structural equation models that use different measures of the level of response to alcohol. Alcohol Clin Exp Res. 2010 May; 34(5):861-8. PMID: 20201931.
      View in: PubMed
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    164. Schuckit M, Smith TL, Danko GP, Isacescu V. Level of response to alcohol measured on the self-rating of the effects of alcohol questionnaire in a group of 40-year-old women. Am J Drug Alcohol Abuse. 2003; 29(1):191-201. PMID: 12731688.
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    165. Paulus MP, Hozack N, Frank L, Brown GG, Schuckit M. Decision making by methamphetamine-dependent subjects is associated with error-rate-independent decrease in prefrontal and parietal activation. Biol Psychiatry. 2003 Jan 01; 53(1):65-74. PMID: 12513946.
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    166. Ehringer MA, Thompson J, Conroy O, Goldman D, Smith TL, Schuckit M, Sikela JM. Human alcoholism studies of genes identified through mouse quantitative trait locus analysis. Addict Biol. 2002 Oct; 7(4):365-71. PMID: 14578011.
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    167. Dick DM, Nurnberger J, Edenberg HJ, Goate A, Crowe R, Rice J, Bucholz KK, Kramer J, Schuckit M, Smith TL, Porjesz B, Begleiter H, Hesselbrock V, Foroud T. Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype. Alcohol Clin Exp Res. 2002 Oct; 26(10):1453-60. PMID: 12394277.
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    168. Schuckit M, Smith TL, Eng MY, Kunovac J. Women who marry men with alcohol-use disorders. Alcohol Clin Exp Res. 2002 Sep; 26(9):1336-43. PMID: 12351927.
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    169. Schuckit M, Danko GP, Smith TL, Buckman KR. The five-year predictive validity of each of the seven DSM-IV items for alcohol dependence among alcoholics. Alcohol Clin Exp Res. 2002 Jul; 26(7):980-7. PMID: 12170107.
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    170. Knight JR, Wechsler H, Kuo M, Seibring M, Weitzman ER, Schuckit M. Alcohol abuse and dependence among U.S. college students. J Stud Alcohol. 2002 May; 63(3):263-70. PMID: 12086126.
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    171. Barnow S, Schuckit M, Lucht M, John U, Freyberger HJ. The importance of a positive family history of alcoholism, parental rejection and emotional warmth, behavioral problems and peer substance use for alcohol problems in teenagers: a path analysis. J Stud Alcohol. 2002 May; 63(3):305-15. PMID: 12086131.
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    172. Porjesz B, Almasy L, Edenberg HJ, Wang K, Chorlian DB, Foroud T, Goate A, Rice JP, O'Connor SJ, Rohrbaugh J, Kuperman S, Bauer LO, Crowe RR, Schuckit M, Hesselbrock V, Conneally PM, Tischfield JA, Li TK, Reich T, Begleiter H. Linkage disequilibrium between the beta frequency of the human EEG and a GABAA receptor gene locus. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3729-33. PMID: 11891318; PMCID: PMC122592.
    173. Schuckit M, Smith TL, Kramer J, Danko G, Volpe FR. The prevalence and clinical course of sedative-hypnotic abuse and dependence in a large cohort. Am J Drug Alcohol Abuse. 2002; 28(1):73-90. PMID: 11853136.
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    174. Paulus MP, Hozack NE, Zauscher BE, Frank L, Brown GG, Braff DL, Schuckit M. Behavioral and functional neuroimaging evidence for prefrontal dysfunction in methamphetamine-dependent subjects. Neuropsychopharmacology. 2002 Jan; 26(1):53-63. PMID: 11751032.
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    175. Bierut LJ, Saccone NL, Rice JP, Goate A, Foroud T, Edenberg H, Almasy L, Conneally PM, Crowe R, Hesselbrock V, Li TK, Nurnberger J, Porjesz B, Schuckit M, Tischfield J, Begleiter H, Reich T. Defining alcohol-related phenotypes in humans. The Collaborative Study on the Genetics of Alcoholism. Alcohol Res Health. 2002; 26(3):208-13. PMID: 12875049.
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    176. Schuckit M, Smith TL, Danko GP, Reich T, Bucholz KK, Bierut LJ. Similarities in the clinical characteristics related to alcohol dependence in two populations. Am J Addict. 2002; 11(1):1-9. PMID: 11876579.
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    177. Schuckit M, Kraft HS, Hurtado SL, Tschinkel SA, Minagawa R, Shaffer RA. A measure of the intensity of response to alcohol in a military population. Am J Drug Alcohol Abuse. 2001 Nov; 27(4):749-57. PMID: 11727887.
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    178. Schuckit M, Smith TL. Correlates of unpredicted outcomes in sons of alcoholics and controls. J Stud Alcohol. 2001 Jul; 62(4):477-85. PMID: 11513225.
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    179. Schuckit M, Smith TL, Danko GP, Bucholz KK, Reich T, Bierut L. Five-year clinical course associated with DSM-IV alcohol abuse or dependence in a large group of men and women. Am J Psychiatry. 2001 Jul; 158(7):1084-90. PMID: 11431230.
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    180. Schuckit M, Smith TL. The clinical course of alcohol dependence associated with a low level of response to alcohol. Addiction. 2001 Jun; 96(6):903-10. PMID: 11399221.
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    181. Schuckit M, Edenberg HJ, Kalmijn J, Flury L, Smith TL, Reich T, Bierut L, Goate A, Foroud T. A genome-wide search for genes that relate to a low level of response to alcohol. Alcohol Clin Exp Res. 2001 Mar; 25(3):323-9. PMID: 11290841.
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    182. Schuckit M, Smith TL. A comparison of correlates of DSM-IV alcohol abuse or dependence among more than 400 sons of alcoholics and controls. Alcohol Clin Exp Res. 2001 Jan; 25(1):1-8. PMID: 11198703.
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    183. Schuckit M, Danko GP, Raimo EB, Smith TL, Eng MY, Carpenter KK, Hesselbrock VM. A preliminary evaluation of the potential usefulness of the diagnoses of polysubstance dependence. J Stud Alcohol. 2001 Jan; 62(1):54-61. PMID: 11271965.
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    184. Schuckit M, Smith TL. The relationships of a family history of alcohol dependence, a low level of response to alcohol and six domains of life functioning to the development of alcohol use disorders. J Stud Alcohol. 2000 Nov; 61(6):827-35. PMID: 11188488.
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    185. Schuckit M. Genetics of the risk for alcoholism. Am J Addict. 2000; 9(2):103-12. PMID: 10934572.
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    186. Schuckit M. New findings in the genetics of alcoholism. JAMA. 1999 May 26; 281(20):1875-6. PMID: 10349877.
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    187. Schuckit M, Smith TL, Tipp JE. The Self-Rating of the Effects of alcohol (SRE) form as a retrospective measure of the risk for alcoholism. Addiction. 1997 Aug; 92(8):979-88. PMID: 9376780.
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