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Jay Giedd

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentPsychiatry
Address9500 Gilman Drive #0603
La Jolla CA 92093
Phone858-822-5214
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, San DiegoDirector, Child and Adolescent Psychiatry2014Department of Psychiatry
    Johns Hopkins Bloomberg School of Public HealthProfessor (adjunct) 2010Dept. of Population, Family and Reproductive Health
    National Institutes of HealthChief, Section on Brain Imaging 2001Child Psychiatry Branch, NIMH
    National Institutes of HealthSenior Staff Clinician1997Child Psychiatry Branch, NIMH
    National Institutes of HealthClinical Staff Fellow1991Child Psychiatry Branch, NIMH
    Duke UniversityChild and Adolescent Psychiatry Fellow1991Duke University Medical Center
    Barrow Neurological InstituteResident in Psychiatry1989Menninger School of Psychiatry
    Menninger School of PsychiatryIntern / Resident in Psychiatry1988Menninger School of Psychiatry
    University of North DakotaBS1982Natural Sciences
    University of North DakotaBA1982Philosophy
    University of North DakotaBA1982Mathematics
    University of North DakotaMD1986School of Medicine
    Collapse Awards and Honors
    Brain and Behavior Research Foundation2013Ruane Prize for Child and Adolescent Psychiatric Research
    American Psychiatric Association2013Blanche F. Ittleson Award for Research in Child Psychiatry
    Society for Neuroscience2012Society for Neuroscience Science Educator Award
    American College of Neuropsychopharmacology2009Joel Elkes Award for Distinguished Research
    NIMH2008NIMH Directors Award for Significant Achievement
    Society for Adolescent Medicine 2007Gallagher Lecture
    Children and Adults with Attention-Deficit/Hyperactivity Disorder (CHADD) Hall of Fame2007Hall of Fame
    The American Society of Psychoanalytic Physicians2006Annual Award of The American Society of Psychoanalytic Physicians
    The New England Council of Child & Adolescent Psychiatry 2006Annual Child Psychiatry Award
    American Assoc. for Klinefelter Syndrome Information and Support 2004Lifetime Achievement Award
    Collegium Internationale Neuro-Psychopharmacologicum2000Max Hamilton Memorial Prize for Outstanding Contributions to Psychopharmacology
    National Institute of Health 1997Fellows Award for Research Excellence
    American College of Neuropsychopharmacology1996Mead Johnson Travel Award
    UND School of Medicine1986Sandoz Award for Outstanding Medical Student in Psychiatry

    Collapse Overview 
    Collapse Overview
    My research focus is to explore the path, mechanisms, and influences on brain development in health and illness through longitudinal studies combining brain imaging, genetics, and psychological/behavioral assessments. Particular areas of current focus are: (1) Adolescent brain maturation, decision making, and the education science/neuroscience interface; (2) The impact of digital technology use on adolescent brain maturation; (3) Twin studies to discern the impact of interacting genetic and environmental factors; (4) Investigations of male/female differences by comparing typically developing youngsters, those with anomalous numbers of sex chromosomes (e.g. XO, XXX, XXY, XYY, XXYY, XXXXY, XXXX), and those with anomalous hormone profiles (e.g. Congenital Adrenal Hyperplasia, Familial Male Precocious Puberty, Androgen Insensitivity Syndrome); (5) Development and implementation of novel methods of image acquisition and analysis including the application of graph theory approaches to assess maturational changes in connectivity; and (6) Studies of 22 clinical psychiatric populations, most actively Autism, Attention-Deficit/Hyperactivity Disorder, and Childhood Onset Schizophrenia.


    Collapse Research 
    Collapse Research Activities and Funding
    Pediatric Brain Imaging
    NIH/NIMH Z01MH002794
    Role: Principal Investigator
    Pediatric Brain Imaging
    NIH/NIMH ZIAMH002794
    Role: Co-Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Videos

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Udhnani M, Maiman M, Blumenthal JD, Clasen LS, Wallace GL, Giedd JN, Raznahan A, Lee NR. Phonemic and Semantic Verbal Fluency in Sex Chromosome Aneuploidy: Contrasting the Effects of Supernumerary X versus Y Chromosomes on Performance. J Int Neuropsychol Soc. 2018 Oct; 24(9):917-927. PMID: 30375320.
      View in: PubMed
    2. Raznahan A, Parikshak NN, Chandran V, Blumenthal JD, Clasen LS, Alexander-Bloch AF, Zinn AR, Wangsa D, Wise J, Murphy DGM, Bolton PF, Ried T, Ross J, Giedd JN, Geschwind DH. Sex-chromosome dosage effects on gene expression in humans. Proc Natl Acad Sci U S A. 2018 Jun 26. PMID: 29946024.
      View in: PubMed
    3. Reardon PK, Seidlitz J, Vandekar S, Liu S, Patel R, Park MTM, Alexander-Bloch A, Clasen LS, Blumenthal JD, Lalonde FM, Giedd JN, Gur R, Gur R, Lerch JP, Chakravarty MM, Satterthwaite T, Shinohara RT, Raznahan A. Normative brain size variation and brain shape diversity in humans. Science. 2018 May 31. PMID: 29853553.
      View in: PubMed
    4. Giedd JN. A Ripe Time for Adolescent Research. J Res Adolesc. 2018 Mar; 28(1):157-159. PMID: 29460353.
      View in: PubMed
    5. Fish AM, Cachia A, Fischer C, Mankiw C, Reardon PK, Clasen LS, Blumenthal JD, Greenstein D, Giedd JN, Mangin JF, Raznahan A. Influences of Brain Size, Sex, and Sex Chromosome Complement on the Architecture of Human Cortical Folding. Cereb Cortex. 2017 Dec 01; 27(12):5557-5567. PMID: 27799275.
      View in: PubMed
    6. Schmitt JE, Giedd JN, Raznahan A, Neale MC. The Genetic Contributions to Maturational Coupling in the Human Cerebrum: A Longitudinal Pediatric Twin Imaging Study. Cereb Cortex. 2017 Aug 01; 1-8. PMID: 28968785.
      View in: PubMed
    7. Mankiw C, Park MTM, Reardon PK, Fish AM, Clasen LS, Greenstein D, Giedd JN, Blumenthal JD, Lerch JP, Chakravarty MM, Raznahan A. Allometric Analysis Detects Brain Size-Independent Effects of Sex and Sex Chromosome Complement on Human Cerebellar Organization. J Neurosci. 2017 May 24; 37(21):5221-5231. PMID: 28314818.
      View in: PubMed
    8. Wallace GL, Dudley K, Anthony L, Pugliese CE, Orionzi B, Clasen L, Lee NR, Giedd JN, Martin A, Raznahan A, Kenworthy L. Divergence of Age-Related Differences in Social-Communication: Improvements for Typically Developing Youth but Declines for Youth with Autism Spectrum Disorder. J Autism Dev Disord. 2017 02; 47(2):472-479. PMID: 27878739.
      View in: PubMed
    9. Smith E, Thurm A, Greenstein D, Farmer C, Swedo S, Giedd J, Raznahan A. Cortical thickness change in autism during early childhood. Hum Brain Mapp. 2016 07; 37(7):2616-29. PMID: 27061356.
      View in: PubMed
    10. Alexander-Bloch A, Clasen L, Stockman M, Ronan L, Lalonde F, Giedd J, Raznahan A. Subtle in-scanner motion biases automated measurement of brain anatomy from in vivo MRI. Hum Brain Mapp. 2016 07; 37(7):2385-97. PMID: 27004471.
      View in: PubMed
    11. Reardon PK, Clasen L, Giedd JN, Blumenthal J, Lerch JP, Chakravarty MM, Raznahan A. An Allometric Analysis of Sex and Sex Chromosome Dosage Effects on Subcortical Anatomy in Humans. J Neurosci. 2016 Feb 24; 36(8):2438-48. PMID: 26911691; PMCID: PMC4764663.
    12. Giedd JN. Adolescent neuroscience of addiction: A new era. Dev Cogn Neurosci. 2015 Dec; 16:192-193. PMID: 26705161.
      View in: PubMed
    13. Lee NR, Anand P, Will E, Adeyemi EI, Clasen LS, Blumenthal JD, Giedd JN, Daunhauer LA, Fidler DJ, Edgin JO. Everyday executive functions in Down syndrome from early childhood to young adulthood: evidence for both unique and shared characteristics compared to youth with sex chromosome trisomy (XXX and XXY). Front Behav Neurosci. 2015; 9:264. PMID: 26539087; PMCID: PMC4611056.
    14. Lee NR, Adeyemi EI, Lin A, Clasen LS, Lalonde FM, Condon E, Driver DI, Shaw P, Gogtay N, Raznahan A, Giedd JN. Dissociations in Cortical Morphometry in Youth with Down Syndrome: Evidence for Reduced Surface Area but Increased Thickness. Cereb Cortex. 2016 07; 26(7):2982-90. PMID: 26088974; PMCID: PMC4898663 [Available on 07/01/17].
    15. Jacobus J, Squeglia LM, Meruelo AD, Castro N, Brumback T, Giedd JN, Tapert SF. Cortical thickness in adolescent marijuana and alcohol users: A three-year prospective study from adolescence to young adulthood. Dev Cogn Neurosci. 2015 Dec; 16:101-109. PMID: 25953106.
      View in: PubMed
    16. Hanley AP, Blumenthal JD, Lee NR, Baker EH, Clasen LS, Giedd JN. Brain and behavior in 48, XXYY syndrome. Neuroimage Clin. 2015; 8:133-9. PMID: 26106537; PMCID: PMC4473812.
    17. Adeyemi EI, Giedd JN, Lee NR. A case study of brain morphometry in triplets discordant for Down syndrome. Am J Med Genet A. 2015 May; 167A(5):1107-10. PMID: 25820455.
      View in: PubMed
    18. Wallace GL, Eisenberg IW, Robustelli B, Dankner N, Kenworthy L, Giedd JN, Martin A. Longitudinal cortical development during adolescence and young adulthood in autism spectrum disorder: increased cortical thinning but comparable surface area changes. J Am Acad Child Adolesc Psychiatry. 2015 Jun; 54(6):464-9. PMID: 26004661.
      View in: PubMed
    19. Lin A, Clasen L, Lee NR, Wallace GL, Lalonde F, Blumenthal J, Giedd JN, Raznahan A. Mapping the stability of human brain asymmetry across five sex-chromosome aneuploidies. J Neurosci. 2015 Jan 07; 35(1):140-5. PMID: 25568109; PMCID: PMC4287138.
    20. Chakravarty MM, Rapoport JL, Giedd JN, Raznahan A, Shaw P, Collins DL, Lerch JP, Gogtay N. Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: a longitudinal study. Hum Brain Mapp. 2015 Apr; 36(4):1458-69. PMID: 25504933.
      View in: PubMed
    21. Lee FS, Heimer H, Giedd JN, Lein ES, Ε estan N, Weinberger DR, Casey BJ. Mental health. Adolescent mental health--opportunity and obligation. Science. 2014 Oct 31; 346(6209):547-9. PMID: 25359951.
      View in: PubMed
    22. Wade BS, Joshi SH, Reuter M, Blumenthal JD, Toga AW, Thompson PM, Giedd JN. Effects of sex chromosome dosage on corpus callosum morphology in supernumerary sex chromosome aneuploidies. Biol Sex Differ. 2014; 5:16. PMID: 25780557; PMCID: PMC4360142.
    23. Davis JM, Searles VB, Anderson N, Keeney J, Raznahan A, Horwood LJ, Fergusson DM, Kennedy MA, Giedd J, Sikela JM. DUF1220 copy number is linearly associated with increased cognitive function as measured by total IQ and mathematical aptitude scores. Hum Genet. 2015 Jan; 134(1):67-75. PMID: 25287832.
      View in: PubMed
    24. Giedd JN, Raznahan A, Alexander-Bloch A, Schmitt E, Gogtay N, Rapoport JL. Child psychiatry branch of the National Institute of Mental Health longitudinal structural magnetic resonance imaging study of human brain development. Neuropsychopharmacology. 2015 Jan; 40(1):43-9. PMID: 25195638; PMCID: PMC4262916.
    25. Raznahan A, Lue Y, Probst F, Greenstein D, Giedd J, Wang C, Lerch J, Swerdloff R. Triangulating the sexually dimorphic brain through high-resolution neuroimaging of murine sex chromosome aneuploidies. Brain Struct Funct. 2015 Nov; 220(6):3581-93. PMID: 25146308.
      View in: PubMed
    26. Raznahan A, Lee NR, Greenstein D, Wallace GL, Blumenthal JD, Clasen LS, Giedd JN. Globally Divergent but Locally Convergent X- and Y-Chromosome Influences on Cortical Development. Cereb Cortex. 2016 Jan; 26(1):70-9. PMID: 25146371; PMCID: PMC4701121 [Available on 01/01/17].
    27. Lee NR, Wallace GL, Raznahan A, Clasen LS, Giedd JN. Trail making test performance in youth varies as a function of anatomical coupling between the prefrontal cortex and distributed cortical regions. Front Psychol. 2014; 5:496. PMID: 25071613; PMCID: PMC4077145.
    28. Mills KL, Goddings AL, Clasen LS, Giedd JN, Blakemore SJ. The developmental mismatch in structural brain maturation during adolescence. Dev Neurosci. 2014; 36(3-4):147-60. PMID: 24993606.
      View in: PubMed
    29. Schmitt JE, Neale MC, Fassassi B, Perez J, Lenroot RK, Wells EM, Giedd JN. The dynamic role of genetics on cortical patterning during childhood and adolescence. Proc Natl Acad Sci U S A. 2014 May 06; 111(18):6774-9. PMID: 24753564; PMCID: PMC4020057.
    30. Alexander-Bloch AF, Reiss PT, Rapoport J, McAdams H, Giedd JN, Bullmore ET, Gogtay N. Abnormal cortical growth in schizophrenia targets normative modules of synchronized development. Biol Psychiatry. 2014 Sep 15; 76(6):438-46. PMID: 24690112.
      View in: PubMed
    31. Raznahan A, Shaw PW, Lerch JP, Clasen LS, Greenstein D, Berman R, Pipitone J, Chakravarty MM, Giedd JN. Longitudinal four-dimensional mapping of subcortical anatomy in human development. Proc Natl Acad Sci U S A. 2014 Jan 28; 111(4):1592-7. PMID: 24474784; PMCID: PMC3910572.
    32. Raznahan A, Probst F, Palmert MR, Giedd JN, Lerch JP. High resolution whole brain imaging of anatomical variation in XO, XX, and XY mice. Neuroimage. 2013 Dec; 83:962-8. PMID: 23891883.
      View in: PubMed
    33. Lee NR, Raznahan A, Wallace GL, Alexander-Bloch A, Clasen LS, Lerch JP, Giedd JN. Anatomical coupling among distributed cortical regions in youth varies as a function of individual differences in vocabulary abilities. Hum Brain Mapp. 2014 May; 35(5):1885-95. PMID: 23728856.
      View in: PubMed
    34. Wallace GL, Robustelli B, Dankner N, Kenworthy L, Giedd JN, Martin A. Increased gyrification, but comparable surface area in adolescents with autism spectrum disorders. Brain. 2013 Jun; 136(Pt 6):1956-67. PMID: 23715094; PMCID: PMC3673467.
    35. Raznahan A, Wallace GL, Antezana L, Greenstein D, Lenroot R, Thurm A, Gozzi M, Spence S, Martin A, Swedo SE, Giedd JN. Compared to what? Early brain overgrowth in autism and the perils of population norms. Biol Psychiatry. 2013 Oct 15; 74(8):563-75. PMID: 23706681.
      View in: PubMed
    36. Ronan L, Voets N, Rua C, Alexander-Bloch A, Hough M, Mackay C, Crow TJ, James A, Giedd JN, Fletcher PC. Differential tangential expansion as a mechanism for cortical gyrification. Cereb Cortex. 2014 Aug; 24(8):2219-28. PMID: 23542881.
      View in: PubMed
    37. Alexander-Bloch A, Giedd JN, Bullmore E. Imaging structural co-variance between human brain regions. Nat Rev Neurosci. 2013 May; 14(5):322-36. PMID: 23531697.
      View in: PubMed
    38. Lopez KC, Lalonde F, Mattai A, Wade B, Clasen L, Rapoport J, Giedd JN. Quantitative morphology of the corpus callosum in obsessive-compulsive disorder. Psychiatry Res. 2013 Apr 30; 212(1):1-6. PMID: 23453697.
      View in: PubMed
    39. Alexander-Bloch A, Raznahan A, Bullmore E, Giedd J. The convergence of maturational change and structural covariance in human cortical networks. J Neurosci. 2013 Feb 13; 33(7):2889-99. PMID: 23407947; PMCID: PMC3711653.
    40. Blumenthal JD, Baker EH, Lee NR, Wade B, Clasen LS, Lenroot RK, Giedd JN. Brain morphological abnormalities in 49,XXXXY syndrome: A pediatric magnetic resonance imaging study. Neuroimage Clin. 2013; 2:197-203. PMID: 23667827.
      View in: PubMed
    41. Wade BS, Stockman M, McLaughlin MJ, Raznahan A, Lalonde F, Giedd JN. Improved corpus callosum area measurements by analysis of adjoining parasagittal slices. Psychiatry Res. 2013 Mar 30; 211(3):221-5. PMID: 23149042.
      View in: PubMed
    42. Raznahan A, Lenroot R, Thurm A, Gozzi M, Hanley A, Spence SJ, Swedo SE, Giedd JN. Mapping cortical anatomy in preschool aged children with autism using surface-based morphometry. Neuroimage Clin. 2012; 2:111-9. PMID: 24179764; PMCID: PMC3777762.
    43. Hedrick A, Lee Y, Wallace GL, Greenstein D, Clasen L, Giedd JN, Raznahan A. Autism risk gene MET variation and cortical thickness in typically developing children and adolescents. Autism Res. 2012 Dec; 5(6):434-9. PMID: 23097380.
      View in: PubMed
    44. Mills KL, Lalonde F, Clasen LS, Giedd JN, Blakemore SJ. Developmental changes in the structure of the social brain in late childhood and adolescence. Soc Cogn Affect Neurosci. 2014 Jan; 9(1):123-31. PMID: 23051898; PMCID: PMC3871734.
    45. Gogtay N, Hua X, Stidd R, Boyle CP, Lee S, Weisinger B, Chavez A, Giedd JN, Clasen L, Toga AW, Rapoport JL, Thompson PM. Delayed white matter growth trajectory in young nonpsychotic siblings of patients with childhood-onset schizophrenia. Arch Gen Psychiatry. 2012 Sep; 69(9):875-84. PMID: 22945617; PMCID: PMC4332876.
    46. Giedd JN, Raznahan A, Mills KL, Lenroot RK. Review: magnetic resonance imaging of male/female differences in human adolescent brain anatomy. Biol Sex Differ. 2012 Aug 21; 3(1):19. PMID: 22908911; PMCID: PMC3472204.
    47. Dumas LJ, O'Bleness MS, Davis JM, Dickens CM, Anderson N, Keeney JG, Jackson J, Sikela M, Raznahan A, Giedd J, Rapoport J, Nagamani SS, Erez A, Brunetti-Pierri N, Sugalski R, Lupski JR, Fingerlin T, Cheung SW, Sikela JM. DUF1220-domain copy number implicated in human brain-size pathology and evolution. Am J Hum Genet. 2012 Sep 07; 91(3):444-54. PMID: 22901949; PMCID: PMC3511999.
    48. Giedd JN. The digital revolution and adolescent brain evolution. J Adolesc Health. 2012 Aug; 51(2):101-5. PMID: 22824439.
      View in: PubMed
    49. Lee NR, Wallace GL, Adeyemi EI, Lopez KC, Blumenthal JD, Clasen LS, Giedd JN. Dosage effects of X and Y chromosomes on language and social functioning in children with supernumerary sex chromosome aneuploidies: implications for idiopathic language impairment and autism spectrum disorders. J Child Psychol Psychiatry. 2012 Oct; 53(10):1072-81. PMID: 22827287.
      View in: PubMed
    50. Raznahan A, Greenstein D, Lee NR, Clasen LS, Giedd JN. Prenatal growth in humans and postnatal brain maturation into late adolescence. Proc Natl Acad Sci U S A. 2012 Jul 10; 109(28):11366-71. PMID: 22689983; PMCID: PMC3396505.
    51. Wallace GL, Shaw P, Lee NR, Clasen LS, Raznahan A, Lenroot RK, Martin A, Giedd JN. Distinct cortical correlates of autistic versus antisocial traits in a longitudinal sample of typically developing youth. J Neurosci. 2012 Apr 04; 32(14):4856-60. PMID: 22492041.
      View in: PubMed
    52. Gozzi M, Nielson DM, Lenroot RK, Ostuni JL, Luckenbaugh DA, Thurm AE, Giedd JN, Swedo SE. A magnetization transfer imaging study of corpus callosum myelination in young children with autism. Biol Psychiatry. 2012 Aug 01; 72(3):215-20. PMID: 22386453.
      View in: PubMed
    53. Raznahan A, Lee Y, Vaituzis C, Tran L, Mackie S, Tiemeier H, Clasen L, Lalonde F, Greenstein D, Pierson R, Giedd JN. Allelic variation within the putative autism spectrum disorder risk gene homeobox A1 and cerebellar maturation in typically developing children and adolescents. Autism Res. 2012 Apr; 5(2):93-100. PMID: 22359339.
      View in: PubMed
    54. Raznahan A, Lerch JP, Lee N, Greenstein D, Wallace GL, Stockman M, Clasen L, Shaw PW, Giedd JN. Patterns of coordinated anatomical change in human cortical development: a longitudinal neuroimaging study of maturational coupling. Neuron. 2011 Dec 08; 72(5):873-84. PMID: 22153381.
      View in: PubMed
    55. Alexander-Bloch A, Lambiotte R, Roberts B, Giedd J, Gogtay N, Bullmore E. The discovery of population differences in network community structure: new methods and applications to brain functional networks in schizophrenia. Neuroimage. 2012 Feb 15; 59(4):3889-900. PMID: 22119652; PMCID: PMC3478383.
    56. Raznahan A, Greenstein D, Lee Y, Long R, Clasen L, Gochman P, Addington A, Giedd JN, Rapoport JL, Gogtay N. Catechol-o-methyl transferase (COMT) val158met polymorphism and adolescent cortical development in patients with childhood-onset schizophrenia, their non-psychotic siblings, and healthy controls. Neuroimage. 2011 Aug 15; 57(4):1517-23. PMID: 21620981.
      View in: PubMed
    57. Raznahan A, Shaw P, Lalonde F, Stockman M, Wallace GL, Greenstein D, Clasen L, Gogtay N, Giedd JN. How does your cortex grow? J Neurosci. 2011 May 11; 31(19):7174-7. PMID: 21562281.
      View in: PubMed
    58. Lee NR, Wallace GL, Clasen LS, Lenroot RK, Blumenthal JD, White SL, Celano MJ, Giedd JN. Executive function in young males with Klinefelter (XXY) syndrome with and without comorbid attention-deficit/hyperactivity disorder. J Int Neuropsychol Soc. 2011 May; 17(3):522-30. PMID: 21418719.
      View in: PubMed
    59. Lenroot RK, Giedd JN. Annual Research Review: Developmental considerations of gene by environment interactions. J Child Psychol Psychiatry. 2011 Apr; 52(4):429-41. PMID: 21391998.
      View in: PubMed
    60. Gilliam M, Stockman M, Malek M, Sharp W, Greenstein D, Lalonde F, Clasen L, Giedd J, Rapoport J, Shaw P. Developmental trajectories of the corpus callosum in attention-deficit/hyperactivity disorder. Biol Psychiatry. 2011 May 01; 69(9):839-46. PMID: 21247556.
      View in: PubMed
    61. Shaw P, Gilliam M, Liverpool M, Weddle C, Malek M, Sharp W, Greenstein D, Evans A, Rapoport J, Giedd J. Cortical development in typically developing children with symptoms of hyperactivity and impulsivity: support for a dimensional view of attention deficit hyperactivity disorder. Am J Psychiatry. 2011 Feb; 168(2):143-51. PMID: 21159727.
      View in: PubMed
    62. Giedd JN, Stockman M, Weddle C, Liverpool M, Alexander-Bloch A, Wallace GL, Lee NR, Lalonde F, Lenroot RK. Anatomic magnetic resonance imaging of the developing child and adolescent brain and effects of genetic variation. Neuropsychol Rev. 2010 Dec; 20(4):349-61. PMID: 21069466.
      View in: PubMed
    63. Alexander-Bloch AF, Gogtay N, Meunier D, Birn R, Clasen L, Lalonde F, Lenroot R, Giedd J, Bullmore ET. Disrupted modularity and local connectivity of brain functional networks in childhood-onset schizophrenia. Front Syst Neurosci. 2010; 4:147. PMID: 21031030; PMCID: PMC2965020.
    64. Wallace GL, Dankner N, Kenworthy L, Giedd JN, Martin A. Age-related temporal and parietal cortical thinning in autism spectrum disorders. Brain. 2010 Dec; 133(Pt 12):3745-54. PMID: 20926367; PMCID: PMC2995883.
    65. Raznahan A, Lee Y, Stidd R, Long R, Greenstein D, Clasen L, Addington A, Gogtay N, Rapoport JL, Giedd JN. Longitudinally mapping the influence of sex and androgen signaling on the dynamics of human cortical maturation in adolescence. Proc Natl Acad Sci U S A. 2010 Sep 28; 107(39):16988-93. PMID: 20841422; PMCID: PMC2947865.
    66. Giedd JN, Rapoport JL. Structural MRI of pediatric brain development: what have we learned and where are we going? Neuron. 2010 Sep 09; 67(5):728-34. PMID: 20826305.
      View in: PubMed
    67. Casanova MF, El-Baz A, Elnakib A, Giedd J, Rumsey JM, Williams EL, Switala AE. Corpus Callosum Shape Analysis with Application to Dyslexia. Transl Neurosci. 2010 Jun; 1(2):124-130. PMID: 22545196.
      View in: PubMed
    68. Schmitt JE, Wallace GL, Lenroot RK, Ordaz SE, Greenstein D, Clasen L, Kendler KS, Neale MC, Giedd JN. A twin study of intracerebral volumetric relationships. Behav Genet. 2010 Mar; 40(2):114-24. PMID: 20112130; PMCID: PMC3403699.
    69. Wallace GL, Lee NR, Prom-Wormley EC, Medland SE, Lenroot RK, Clasen LS, Schmitt JE, Neale MC, Giedd JN. A bivariate twin study of regional brain volumes and verbal and nonverbal intellectual skills during childhood and adolescence. Behav Genet. 2010 Mar; 40(2):125-34. PMID: 20112131.
      View in: PubMed
    70. Correia S, Hubbard E, Hassenstab J, Yip A, Vymazal J, Herynek V, Giedd J, Murphy DL, Greenberg BD. Basal ganglia MR relaxometry in obsessive-compulsive disorder: T2 depends upon age of symptom onset. Brain Imaging Behav. 2010 Mar; 4(1):35-45. PMID: 20503112.
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    71. Raznahan A, Cutter W, Lalonde F, Robertson D, Daly E, Conway GS, Skuse DH, Ross J, Lerch JP, Giedd JN, Murphy DD. Cortical anatomy in human X monosomy. Neuroimage. 2010 Feb 15; 49(4):2915-23. PMID: 19948228.
      View in: PubMed
    72. Tiemeier H, Lenroot RK, Greenstein DK, Tran L, Pierson R, Giedd JN. Cerebellum development during childhood and adolescence: a longitudinal morphometric MRI study. Neuroimage. 2010 Jan 01; 49(1):63-70. PMID: 19683586.
      View in: PubMed
    73. Casanova MF, El-Baz AS, Giedd J, Rumsey JM, Switala AE. Increased white matter gyral depth in dyslexia: implications for corticocortical connectivity. J Autism Dev Disord. 2010 Jan; 40(1):21-9. PMID: 19609661.
      View in: PubMed
    74. Giedd JN, Lalonde FM, Celano MJ, White SL, Wallace GL, Lee NR, Lenroot RK. Anatomical brain magnetic resonance imaging of typically developing children and adolescents. J Am Acad Child Adolesc Psychiatry. 2009 May; 48(5):465-70. PMID: 19395901.
      View in: PubMed
    75. Webb SJ, Sparks BF, Friedman SD, Shaw DW, Giedd J, Dawson G, Dager SR. Cerebellar vermal volumes and behavioral correlates in children with autism spectrum disorder. Psychiatry Res. 2009 Apr 30; 172(1):61-7. PMID: 19243924; PMCID: PMC2676721.
    76. Casanova MF, El-Baz A, Mott M, Mannheim G, Hassan H, Fahmi R, Giedd J, Rumsey JM, Switala AE, Farag A. Reduced gyral window and corpus callosum size in autism: possible macroscopic correlates of a minicolumnopathy. J Autism Dev Disord. 2009 May; 39(5):751-64. PMID: 19148739.
      View in: PubMed
    77. Lenroot RK, Lee NR, Giedd JN. Effects of sex chromosome aneuploidies on brain development: evidence from neuroimaging studies. Dev Disabil Res Rev. 2009; 15(4):318-27. PMID: 20014372.
      View in: PubMed
    78. Lenroot RK, Schmitt JE, Ordaz SJ, Wallace GL, Neale MC, Lerch JP, Kendler KS, Evans AC, Giedd JN. Differences in genetic and environmental influences on the human cerebral cortex associated with development during childhood and adolescence. Hum Brain Mapp. 2009 Jan; 30(1):163-74. PMID: 18041741.
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    88. Giedd JN, Schmitt JE, Neale MC. Structural brain magnetic resonance imaging of pediatric twins. Hum Brain Mapp. 2007 Jun; 28(6):474-81. PMID: 17437295.
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    90. Giedd JN, Clasen LS, Wallace GL, Lenroot RK, Lerch JP, Wells EM, Blumenthal JD, Nelson JE, Tossell JW, Stayer C, Evans AC, Samango-Sprouse CA. XXY (Klinefelter syndrome): a pediatric quantitative brain magnetic resonance imaging case-control study. Pediatrics. 2007 Jan; 119(1):e232-40. PMID: 17200249.
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    94. Lenroot RK, Giedd JN. Brain development in children and adolescents: insights from anatomical magnetic resonance imaging. Neurosci Biobehav Rev. 2006; 30(6):718-29. PMID: 16887188.
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    95. Boger-Megiddo I, Shaw DW, Friedman SD, Sparks BF, Artru AA, Giedd JN, Dawson G, Dager SR. Corpus callosum morphometrics in young children with autism spectrum disorder. J Autism Dev Disord. 2006 Aug; 36(6):733-9. PMID: 16625438.
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    97. Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, Giedd J, Castellanos FX, Rapoport J. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder. Arch Gen Psychiatry. 2006 May; 63(5):540-9. PMID: 16651511.
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    98. Lerch JP, Worsley K, Shaw WP, Greenstein DK, Lenroot RK, Giedd J, Evans AC. Mapping anatomical correlations across cerebral cortex (MACACC) using cortical thickness from MRI. Neuroimage. 2006 Jul 01; 31(3):993-1003. PMID: 16624590.
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    100. Vidal CN, Rapoport JL, Hayashi KM, Geaga JA, Sui Y, McLemore LE, Alaghband Y, Giedd JN, Gochman P, Blumenthal J, Gogtay N, Nicolson R, Toga AW, Thompson PM. Dynamically spreading frontal and cingulate deficits mapped in adolescents with schizophrenia. Arch Gen Psychiatry. 2006 Jan; 63(1):25-34. PMID: 16389194.
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    101. Merke DP, Giedd JN, Keil MF, Mehlinger SL, Wiggs EA, Holzer S, Rawson E, Vaituzis AC, Stratakis CA, Chrousos GP. Children experience cognitive decline despite reversal of brain atrophy one year after resolution of Cushing syndrome. J Clin Endocrinol Metab. 2005 May; 90(5):2531-6. PMID: 15741254.
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    102. Rose AB, Merke DP, Clasen LS, Rosenthal MA, Wallace GL, Vaituzis AC, Fields JD, Giedd JN. Effects of hormones and sex chromosomes on stress-influenced regions of the developing pediatric brain. Ann N Y Acad Sci. 2004 Dec; 1032:231-3. PMID: 15677417.
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    103. Saluja G, Iachan R, Scheidt PC, Overpeck MD, Sun W, Giedd JN. Prevalence of and risk factors for depressive symptoms among young adolescents. Arch Pediatr Adolesc Med. 2004 Aug; 158(8):760-5. PMID: 15289248.
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    105. Giedd JN. Structural magnetic resonance imaging of the adolescent brain. Ann N Y Acad Sci. 2004 Jun; 1021:77-85. PMID: 15251877.
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    108. Sporn AL, Greenstein DK, Gogtay N, Jeffries NO, Lenane M, Gochman P, Clasen LS, Blumenthal J, Giedd JN, Rapoport JL. Progressive brain volume loss during adolescence in childhood-onset schizophrenia. Am J Psychiatry. 2003 Dec; 160(12):2181-9. PMID: 14638588.
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    109. Castellanos FX, Sharp WS, Gottesman RF, Greenstein DK, Giedd JN, Rapoport JL. Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder. Am J Psychiatry. 2003 Sep; 160(9):1693-6. PMID: 12944348.
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    110. Keller A, Jeffries NO, Blumenthal J, Clasen LS, Liu H, Giedd JN, Rapoport JL. Corpus callosum development in childhood-onset schizophrenia. Schizophr Res. 2003 Jul 01; 62(1-2):105-14. PMID: 12765750.
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    111. Merke DP, Fields JD, Keil MF, Vaituzis AC, Chrousos GP, Giedd JN. Children with classic congenital adrenal hyperplasia have decreased amygdala volume: potential prenatal and postnatal hormonal effects. J Clin Endocrinol Metab. 2003 Apr; 88(4):1760-5. PMID: 12679470.
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    112. Gogtay N, Sporn A, Clasen LS, Greenstein D, Giedd JN, Lenane M, Gochman PA, Zijdenbos A, Rapoport JL. Structural brain MRI abnormalities in healthy siblings of patients with childhood-onset schizophrenia. Am J Psychiatry. 2003 Mar; 160(3):569-71. PMID: 12611841.
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    113. Chung MK, Worsley KJ, Robbins S, Paus T, Taylor J, Giedd JN, Rapoport JL, Evans AC. Deformation-based surface morphometry applied to gray matter deformation. Neuroimage. 2003 Feb; 18(2):198-213. PMID: 12595176.
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    114. Giedd JN. The anatomy of mentalization: a view from developmental neuroimaging. Bull Menninger Clin. 2003; 67(2):132-42. PMID: 14604098.
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    115. Keller A, Castellanos FX, Vaituzis AC, Jeffries NO, Giedd JN, Rapoport JL. Progressive loss of cerebellar volume in childhood-onset schizophrenia. Am J Psychiatry. 2003 Jan; 160(1):128-33. PMID: 12505811.
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    116. Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS, Blumenthal JD, James RS, Ebens CL, Walter JM, Zijdenbos A, Evans AC, Giedd JN, Rapoport JL. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder. JAMA. 2002 Oct 09; 288(14):1740-8. PMID: 12365958.
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    117. Gogtay N, Giedd J, Rapoport JL. Brain development in healthy, hyperactive, and psychotic children. Arch Neurol. 2002 Aug; 59(8):1244-8. PMID: 12164719.
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    118. Blumenthal JD, Zijdenbos A, Molloy E, Giedd JN. Motion artifact in magnetic resonance imaging: implications for automated analysis. Neuroimage. 2002 May; 16(1):89-92. PMID: 11969320.
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