Siamak Amirfakhri

Title(s)SRA 3, Cancer Center
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A new locoregional mouse model of gastric cancer for identifying probes for fluorescence guided surgery. Surgery. 2025 05; 181:109270. Cox KE, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 40043513.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Bright and Specific Targeting of Metastatic Lymph Nodes in Orthotopic Mouse Models of Gastric Cancer with a Fluorescent Anti-CEA Antibody. Ann Surg Oncol. 2025 May; 32(5):3796-3803. Cox KE, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 39878844.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    3. Targeting Human Pancreatic Cancer with a Fluorophore-Conjugated Mucin 4 (MUC4) Antibody: Initial Characterization in Orthotopic Cell Line Mouse Models. J Clin Med. 2024 Oct 18; 13(20). Jaiswal S, Cox KE, Amirfakhri S, Din Parast Saleh A, Kobayashi K, Lwin TM, Talib S, Aithal A, Mallya K, Jain M, Mohs AM, Hoffman RM, Batra SK, Bouvet M. PMID: 39458160; PMCID: PMC11508345.
      View in: PubMed   Mentions:
    4. Accurate Co-Localization of Luciferase Expression and Fluorescent Anti-CEA Antibody Targeting of Liver Metastases in an Orthotopic Mouse Model of Colon Cancer. Cancers (Basel). 2024 Sep 29; 16(19). Lee KH, Cox KE, Amirfakhri S, Jaiswal S, Liu S, Hosseini M, Lwin TM, Yazaki PJ, Hoffman RM, Bouvet M. PMID: 39409961; PMCID: PMC11475688.
      View in: PubMed   Mentions:
    5. Targeting Patient-Derived Orthotopic Gastric Cancers with a Fluorescent Humanized Anti-CEA Antibody. Ann Surg Oncol. 2024 Sep; 31(9):6291-6299. Cox KE, Turner MA, Lwin TM, Amirfakhri S, Kelly KJ, Hosseini M, Ghosh P, Obonyo M, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 38888861; PMCID: PMC11300635.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimalsCells
    6. Machine-Learning Identifies a Strategy for Differentiation Therapy in Solid Tumors. bioRxiv. 2024 Jan 17. Sinha S, Alcantara J, Perry K, Castillo V, Espinoza CR, Taheri S, Vidales E, Tindle C, Adel A, Amirfakhri S, Sawires JR, Yang J, Bouvet M, Sahoo D, Ghosh P. PMID: 37745574; PMCID: PMC10515918.
      View in: PubMed   Mentions:
    7. Humanized Anti-Carcinoembryonic Antigen Antibodies Brightly Target and Label Gastric Cancer in Orthotopic Mouse Models. J Surg Res. 2024 01; 293:701-708. Cox KE, Turner MA, Amirfakhri S, Lwin TM, Hosseini M, Ghosh P, Obonyo M, Murakami T, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 37839102; PMCID: PMC11060874.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    8. PEGylated Fluorescent Anti-carcinoembryonic Antigen Antibody Labels Colorectal Cancer Tumors in Orthotopic Mouse Models. J Surg Res. 2023 11; 291:596-602. Turner MA, Amirfakhri S, Nishino H, Neel NC, Hosseini M, Cox KE, Lwin TM, Li L, Hong T, Sherman A, Shively JE, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 37540977.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Highly Selective Targeting of Pancreatic Cancer in the Liver with a Near-Infrared Anti-MUC5AC Probe in a PDOX Mouse Model: A Proof-of-Concept Study. J Pers Med. 2023 May 20; 13(5). Turner MA, Cox KE, Neel N, Amirfakhri S, Nishino H, Clary BM, Hosseini M, Natarajan G, Mallya K, Mohs AM, Hoffman RM, Batra SK, Bouvet M. PMID: 37241027; PMCID: PMC10221372.
      View in: PubMed   Mentions:
    10. Specific Targeting and Labeling of Colonic Polyps in CPC-APC Mice with Mucin 5AC Fluorescent Antibodies: A Model for Detection of Early Colon Cancer. Curr Issues Mol Biol. 2023 Apr 11; 45(4):3347-3358. Turner MA, Cox KE, Liu S, Neel N, Amirfakhri S, Nishino H, Hosseini M, Alcantara JA, Abd El-Hafeez AA, Lwin TM, Mallya K, Pisegna JR, Singh SK, Ghosh P, Hoffman RM, Batra SK, Bouvet M. PMID: 37185743; PMCID: PMC10136452.
      View in: PubMed   Mentions: 1     Fields:    
    11. Proof of Principle of Combining Fluorescence-Guided Surgery with Photoimmunotherapy to Improve the Outcome of Pancreatic Cancer Therapy in an Orthotopic Mouse Model. Ann Surg Oncol. 2023 Jan; 30(1):618-625. Nishino H, Turner MA, Amirfakhri S, Lwin TM, Hosseini M, Singer BB, Hoffman RM, Bouvet M. PMID: 36057899; PMCID: PMC9726788.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    12. Proof of concept of improved fluorescence-guided surgery of colon cancer liver metastasis using color-coded imaging of a tumor-labeling fluorescent antibody and indocyanine green restricted to the adjacent liver segment. Surgery. 2022 10; 172(4):1156-1163. Nishino H, Turner MA, Amirfakhri S, Hollandsworth HM, Lwin TM, Hosseini M, Framery B, Cailler F, Pèlegrin A, Hoffman RM, Bouvet M. PMID: 35927078.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    13. Anti-mucin 4 fluorescent antibody brightly targets colon cancer in patient-derived orthotopic xenograft mouse models: A proof-of-concept study for future clinical applications. Am J Surg. 2022 10; 224(4):1081-1085. Turner MA, Hollandsworth HM, Amirfakhri S, Lwin TM, Nishino H, Neel NC, Natarajan G, Kaur S, Mallya K, Hoffman RM, Batra SK, Bouvet M. PMID: 35715267; PMCID: PMC9987031.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    14. Fluorescent Anti-CEA Nanobody for Rapid Tumor-Targeting and Imaging in Mouse Models of Pancreatic Cancer. Biomolecules. 2022 05 16; 12(5). Lwin TM, Turner MA, Nishino H, Amirfakhri S, Hernot S, Hoffman RM, Bouvet M. PMID: 35625638; PMCID: PMC9138244.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    15. Fluorescence Molecular Targeting of Colon Cancer to Visualize the Invisible. Cells. 2022 01 12; 11(2). Lwin TM, Turner MA, Amirfakhri S, Nishino H, Hoffman RM, Bouvet M. PMID: 35053365; PMCID: PMC8773892.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    16. Monocytes engineered with iSNAP inhibit human B-lymphoma progression. Bioeng Transl Med. 2022 May; 7(2):e10285. Wu H, Amirfakhri S, Lin HH, Hollandsworth H, Filemoni F, Liu Y, Wu Y, Li JYS, Xu H, Chien S, Bouvet M, Wang Y. PMID: 35600645; PMCID: PMC9115687.
      View in: PubMed   Mentions: 1  
    17. Fluorescent Anti-MUC5AC Brightly Targets Pancreatic Cancer in a Patient-derived Orthotopic Xenograft. In Vivo. 2022 Jan-Feb; 36(1):57-62. Turner MA, Hollandsworth HM, Nishino H, Amirfakhri S, Lwin TM, Lowy AM, Kaur S, Natarajan G, Mallya K, Hoffman RM, Batra SK, Bouvet M. PMID: 34972700; PMCID: PMC8765132.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    18. The Use of Fluorescent Anti-CEA Antibodies to Label, Resect and Treat Cancers: A Review. Biomolecules. 2021 Dec 02; 11(12). Turner MA, Lwin TM, Amirfakhri S, Nishino H, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 34944463; PMCID: PMC8699160.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    19. Rapid tumor-labeling kinetics with a site-specific near-infrared anti-CEA nanobody in a patient-derived orthotopic xenograft mouse model of colon cancer. J Surg Oncol. 2021 Dec; 124(7):1121-1127. Lwin TM, Turner MA, Amirfakhri S, Nishino H, Debie P, Cosman BC, Hoffman RM, Hernot S, Bouvet M. PMID: 34309885; PMCID: PMC8556245.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    20. A Patient-Derived Orthotopic Xenograft Model of Gastroesophageal-Junction Adenocarcinoma Translated to the Clinic by Tumor-Targeting Fluorescent Antibodies to Carcinoembryonic-Antigen-Related Cell-Adhesion Molecules. In Vivo. 2021 Jul-Aug; 35(4):1959-1963. Turner MA, Amirfakhri S, Nishino H, Lwin TM, Savides TJ, Reid TR, Singer BB, Hoffman RM, Bouvet M. PMID: 34182469; PMCID: PMC8286470.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    21. A Novel Color-Coded Liver Metastasis Mouse Model to Distinguish Tumor and Adjacent Liver Segment. J Surg Res. 2021 08; 264:327-333. Nishino H, Hollandsworth HM, Amirfakhri S, Tashiro Y, Yamamoto J, Turner MA, Lwin TM, Singer BB, Hoffman RM, Bouvet M. PMID: 33848831; PMCID: PMC8222089.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimals
    22. Ligation Method to Specifically Label a Liver Segment With Indocyanine Green in an Orthotopic Nude-Mouse Liver-Metastasis Model. In Vivo. 2020 Nov-Dec; 34(6):3159-3162. Nishino H, Hollandsworth HM, Tashiro Y, Yamamoto J, Amirfakhri S, Filemoni F, Sugisawa N, Hoffman RM, Bouvet M. PMID: 33144419; PMCID: PMC7811678.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    23. Sutureless Surgical Orthotopic Implantation Technique of Primary and Metastatic Cancer in the Liver of Mouse Models. In Vivo. 2020 Nov-Dec; 34(6):3153-3157. Nishino H, Hollandsworth HM, Sugisawa N, Yamamoto J, Tashiro Y, Inubushi S, Hamada K, Sun YU, Lim H, Amirfakhri S, Filemoni F, Hoffman RM, Bouvet M. PMID: 33144418; PMCID: PMC7811661.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    24. Indocyanine Green Labels an Orthotopic Nude-Mouse Model of Very-Early Colon-Cancer Liver Metastases. In Vivo. 2020 Sep-Oct; 34(5):2277-2280. Tashiro Y, Hollandsworth HM, Nishino H, Yamamoto J, Amirfakhri S, Filemoni F, Sugisawa N, Aoki T, Murakami M, Hoffman RM, Bouvet M. PMID: 32871750; PMCID: PMC7652533.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    25. Humanized Fluorescent Tumor-associated Glycoprotein-72 Antibody Selectively Labels Colon-cancer Liver Metastases in Orthotopic Mouse Models. In Vivo. 2020 Sep-Oct; 34(5):2303-2307. Hollandsworth HM, Nishino H, Turner M, Amirfakhri S, Filemoni F, Hoffman RM, Yazaki PJ, Bouvet M. PMID: 32871754; PMCID: PMC7652487.
      View in: PubMed   Mentions: 4     Fields:    Translation:Animals
    26. Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adhesion molecules. Transl Oncol. 2020 Dec; 13(12):100857. Hollandsworth HM, Schmitt V, Amirfakhri S, Filemoni F, Schmidt A, Landström M, Lyndin M, Backert S, Gerhard M, Wennemuth G, Hoffman RM, Singer BB, Bouvet M. PMID: 32866936; PMCID: PMC7475271.
      View in: PubMed   Mentions: 5  
    27. Near-infrared photoimmunotherapy is effective treatment for colorectal cancer in orthotopic nude-mouse models. PLoS One. 2020; 15(6):e0234643. Hollandsworth HM, Amirfakhri S, Filemoni F, Molnar J, Hoffman RM, Yazaki P, Bouvet M. PMID: 32555717; PMCID: PMC7302706.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    28. Tumor-specific near-infrared nanobody probe rapidly labels tumors in an orthotopic mouse model of pancreatic cancer. Surgery. 2020 07; 168(1):85-91. Lwin TM, Hernot S, Hollandsworth H, Amirfakhri S, Filemoni F, Debie P, Hoffman RM, Bouvet M. PMID: 32370916; PMCID: PMC7311276.
      View in: PubMed   Mentions: 14     Fields:    Translation:Animals
    29. Humanized Anti-Tumor-Associated Glycoprotein-72 for Submillimeter Near-Infrared Detection of Colon Cancer in Metastatic Mouse Models. J Surg Res. 2020 08; 252:16-21. Hollandsworth HM, Amirfakhri S, Filemoni F, Hoffman RM, Molnar J, Yazaki PJ, Bouvet M. PMID: 32217350; PMCID: PMC7295682.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    30. Anti-carcinoembryonic antigen-related cell adhesion molecule antibody for fluorescence visualization of primary colon cancer and metastases in patient-derived orthotopic xenograft mouse models. Oncotarget. 2020 Jan 28; 11(4):429-439. Hollandsworth HM, Amirfakhri S, Filemoni F, Schmitt V, Wennemuth G, Schmidt A, Hoffman RM, Singer BB, Bouvet M. PMID: 32064046; PMCID: PMC6996915.
      View in: PubMed   Mentions: 18     Fields:    
    31. Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX Mouse Models. J Surg Res. 2019 10; 242:145-150. Hollandsworth HM, Lwin TM, Amirfakhri S, Filemoni F, Batra SK, Hoffman RM, Dhawan P, Bouvet M. PMID: 31077946; PMCID: PMC7144806.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimalsCells
    32. Fluorescent humanized anti-CEA antibody specifically labels metastatic pancreatic cancer in a patient-derived orthotopic xenograft (PDOX) mouse model. Oncotarget. 2018 Dec 18; 9(99):37333-37342. Lwin TM, Miyake K, Murakami T, DeLong JC, Amirfakhri S, Filemoni F, Yoon SN, Yazaki PJ, Shivley JE, Datnow B, Clary BM, Hoffman RM, Bouvet M. PMID: 30647873; PMCID: PMC6324662.
      View in: PubMed   Mentions: 12     Fields:    
    33. Effects of Conditioned Medium from Breast Cancer Cells on Tlr2 Expression in Nb4 Cells. Asian Pac J Cancer Prev. 2015; 16(18):8445-50. Amirfakhri S, Salimi A, Fernandez N. PMID: 26745099.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
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