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    Anne Wallace

    TitleProfessor Of Clinical
    SchoolUniversity of California, San Diego
    DepartmentSurgery
    Address9500 Gilman Drive #0987
    CA La Jolla 92093
    Phone858-822-6193
    vCardDownload vCard

      Collapse Overview 
      Collapse Overview
      Research Overview
      Dr. Wallace employs nuclear and fluorescence imaging to detect and stage melanoma and breast cancer. She also employs advanced imaging techniques to study stem cell reconstructive surgery.

      Research Topics
      - Cancer
      - Regeneration/Stem Cells

      Current Project Titles
      - Stem Cell Tracking after Reconstructive Surgery
      - Fluorescence Detection of Breast Cancer
      - Sentinel Lymph Node Mapping via Fluorescence Detection

      Profile
      Dr. Anne Wallace is a member of both the Division of General Surgery and the Division of Plastic Surgery. She has directed the breast program since 1995 at the UC San Diego Moores Cancer Center. The Breast Care Unit is a team of doctors, nurses, researchers, and other health professionals who work closely together to provide excellent care and the latest available treatments for patients who have breast cancer.

      Dr. Wallace participates in the Translational Oncology Program at the UC San Diego Moores Cancer Center. In her research, Dr. Wallace studies the causes, behavior, and treatment of breast cancer and melanoma. Her special research interests include breast cancer prevention and the improvement of techniques for sentinel lymph node biopsy. She is an investigator in the ongoing National Surgical Adjuvant Breast and Bowel Project (NSABP) study of breast cancer treatments as well as several other studies. She also collaborates with basic science researchers to develop new ways to detect breast cancer early and to identify individuals who are at higher risk for developing the disease.

      Dr. Wallace holds leadership positions in several national and local cancer organizations, including the American Cancer Society, the American Melanoma Society, and the California Breast Cancer Research Council. She has served as Vice President of Cancer Control for the Golden Triangle Division of the American Cancer Society and as Chairman of the California Breast Cancer Research Council.

      In 1999, the Komen Foundation honored Dr. Wallace as Breast Cancer Clinician of the Year. She was named the Clinical Teacher of the Year for 2000 in the UC San Diego Division of Plastic Surgery.


      Collapse Research 
      Collapse Research Activities and Funding
      A New Radiotracer for Prostate Sentinel Node Mapping
      NIH/NCI R21CA112940May 19, 2006 - Apr 30, 2010
      Role: Principal Investigator
      A Phase II Study of a New Sentinel Node Radiotracer
      NIH/NCI R21CA097643Sep 24, 2002 - Aug 31, 2005
      Role: Principal Investigator

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      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Unkart JT, Chen SL, Wapnir IL, González JE, Harootunian A, Wallace A. Erratum to: Intraoperative Tumor Detection Using a Ratiometric Activatable Fluorescent Peptide: A First-in-Human Phase 1 Study. Ann Surg Oncol. 2017 Jul 31. PMID: 28762115.
        View in: PubMed
      2. Unkart JT, Wallace A. Use of 99mTc-Tilmanocept as a Single Agent for Sentinel Lymph Node Identification in Breast Cancer: A Retrospective Pilot Study. J Nucl Med Technol. 2017 Sep; 45(3):181-184. PMID: 28705929.
        View in: PubMed
      3. Unkart JT, Chen SL, Wapnir IL, González JE, Harootunian A, Wallace A. Intraoperative Tumor Detection Using a Ratiometric Activatable Fluorescent Peptide: A First-in-Human Phase 1 Study. Ann Surg Oncol. 2017 Jul 11. PMID: 28699134.
        View in: PubMed
      4. Unkart JT, Hosseini A, Wallace A. Tc-99m tilmanocept versus Tc-99m sulfur colloid in breast cancer sentinel lymph node identification: Results from a randomized, blinded clinical trial. J Surg Oncol. 2017 Jul 10. PMID: 28695567.
        View in: PubMed
      5. Finn DM, Ilfeld BM, Unkart JT, Madison SJ, Suresh PJ, Sandhu NPS, Kormylo NJ, Malhotra N, Loland VJ, Wallace MS, Wen CH, Morgan AC, Wallace A. Post-mastectomy cancer recurrence with and without a continuous paravertebral block in the immediate postoperative period: a prospective multi-year follow-up pilot study of a randomized, triple-masked, placebo-controlled investigation. J Anesth. 2017 Jun; 31(3):374-379. PMID: 28364165.
        View in: PubMed
      6. Unkart JT, Padwal JA, Ilfeld BM, Wallace A. Treatment of Post-Latissimus Dorsi Flap Breast Reconstruction Pain With Continuous Paravertebral Nerve Blocks: A Retrospective Review. Anesth Pain Med. 2016 Oct; 6(5):e39476. PMID: 27847703.
        View in: PubMed
      7. Park JW, Liu MC, Yee D, Yau C, van 't Veer LJ, Symmans WF, Paoloni M, Perlmutter J, Hylton NM, Hogarth M, DeMichele A, Buxton MB, Chien AJ, Wallace A, Boughey JC, Haddad TC, Chui SY, Kemmer KA, Kaplan HG, Isaacs C, Nanda R, Tripathy D, Albain KS, Edmiston KK, Elias AD, Northfelt DW, Pusztai L, Moulder SL, Lang JE, Viscusi RK, Euhus DM, Haley BB, Khan QJ, Wood WC, Melisko M, Schwab R, Helsten T, Lyandres J, Davis SE, Hirst GL, Sanil A, Esserman LJ, Berry DA. Adaptive Randomization of Neratinib in Early Breast Cancer. N Engl J Med. 2016 Jul 07; 375(1):11-22. PMID: 27406346.
        View in: PubMed
      8. Rugo HS, Olopade OI, DeMichele A, Yau C, van 't Veer LJ, Buxton MB, Hogarth M, Hylton NM, Paoloni M, Perlmutter J, Symmans WF, Yee D, Chien AJ, Wallace A, Kaplan HG, Boughey JC, Haddad TC, Albain KS, Liu MC, Isaacs C, Khan QJ, Lang JE, Viscusi RK, Pusztai L, Moulder SL, Chui SY, Kemmer KA, Elias AD, Edmiston KK, Euhus DM, Haley BB, Nanda R, Northfelt DW, Tripathy D, Wood WC, Ewing C, Schwab R, Lyandres J, Davis SE, Hirst GL, Sanil A, Berry DA, Esserman LJ. Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer. N Engl J Med. 2016 Jul 07; 375(1):23-34. PMID: 27406347.
        View in: PubMed
      9. Unkart JT, Reid CM, Baumgartner JM, Wallace A, Kelly CJ. Are self-identified "disadvantaged" students less likely to enter surgical residencies? A single-institution study. J Surg Res. 2016 May 15; 202(2):253-8. PMID: 27229098.
        View in: PubMed
      10. Mailey B, Baker JL, Hosseini A, Collins J, Suliman A, Wallace A, Cohen SR. Evaluation of Facial Volume Changes after Rejuvenation Surgery Using a 3-Dimensional Camera. Aesthet Surg J. 2016 Apr; 36(4):379-87. PMID: 26628536.
        View in: PubMed
      11. Schwab RB, Kato S, Crain B, Pu M, Messer K, Weidner N, Blair SL, Wallace A, Carson DA, Parker BA. A window-of-opportunity biomarker study of etodolac in resectable breast cancer. Cancer Med. 2015 Oct; 4(10):1583-8. PMID: 26275572; PMCID: PMC4618628.
        View in: PubMed, PubMed Central
      12. Unkart JT, Baker JL, Hosseini A, Hoh CK, Wallace MS, Vera DR, Wallace A. Comparison of Post-injection Site Pain Between Technetium Sulfur Colloid and Technetium Tilmanocept in Breast Cancer Patients Undergoing Sentinel Lymph Node Biopsy. Ann Surg Oncol. 2015 Dec; 22 Suppl 3:S559-65. PMID: 26275779; PMCID: PMC4686557.
        View in: PubMed, PubMed Central
      13. Agarwal RR, Wallace A, Madison SJ, Morgan AC, Mascha EJ, Ilfeld BM. Single-injection thoracic paravertebral block and postoperative analgesia after mastectomy: a retrospective cohort study. J Clin Anesth. 2015 Aug; 27(5):371-4. PMID: 25957529; PMCID: PMC4467997.
        View in: PubMed, PubMed Central
      14. Ilfeld BM, Madison SJ, Suresh PJ, Sandhu NS, Kormylo NJ, Malhotra N, Loland VJ, Wallace MS, Mascha EJ, Xu Z, Wen CH, Morgan AC, Wallace A. Persistent postmastectomy pain and pain-related physical and emotional functioning with and without a continuous paravertebral nerve block: a prospective 1-year follow-up assessment of a randomized, triple-masked, placebo-controlled study. Ann Surg Oncol. 2015; 22(6):2017-25. PMID: 25413267.
        View in: PubMed
      15. Weiss A, Tran V, Baker J, Farnaz H, Wallace A, Chang D, Ojeda-Fournier H, Blair SL. Increased likelihood of mastectomy in human epidermal growth factor receptor 2-positive ductal carcinoma in situ. Am Surg. 2014 Oct; 80(10):936-9. PMID: 25264633.
        View in: PubMed
      16. Baker JL, Schwab RB, Wallace A, Madlensky L. Breast cancer in a RAD51D mutation carrier: case report and review of the literature. Clin Breast Cancer. 2015 Feb; 15(1):e71-5. PMID: 25445424.
        View in: PubMed
      17. Baker JL, Pu M, Tokin CA, Hoh CK, Vera DR, Messer K, Wallace A. Comparison of [(99m)Tc]tilmanocept and filtered [(99m)Tc]sulfur colloid for identification of SLNs in breast cancer patients. Ann Surg Oncol. 2015 Jan; 22(1):40-5. PMID: 25069859; PMCID: PMC4273083.
        View in: PubMed, PubMed Central
      18. Hosseini A, Baker JL, Tokin CA, Qin Z, Hall DJ, Stupak DG, Hayashi T, Wallace A, Vera DR. Fluorescent-tilmanocept for tumor margin analysis in the mouse model. J Surg Res. 2014 Aug; 190(2):528-34. PMID: 24923630; PMCID: PMC4201840.
        View in: PubMed, PubMed Central
      19. Ilfeld BM, Madison SJ, Suresh PJ, Sandhu NS, Kormylo NJ, Malhotra N, Loland VJ, Wallace MS, Proudfoot JA, Morgan AC, Wen CH, Wallace A. Treatment of postmastectomy pain with ambulatory continuous paravertebral nerve blocks: a randomized, triple-masked, placebo-controlled study. Reg Anesth Pain Med. 2014 Mar-Apr; 39(2):89-96. PMID: 24448512; PMCID: PMC3944096.
        View in: PubMed, PubMed Central
      20. Mailey B, Hosseini A, Baker J, Young A, Alfonso Z, Hicok K, Wallace A, Cohen SR. Adipose-derived stem cells: methods for isolation and applications for clinical use. Methods Mol Biol. 2014; 1210:161-81. PMID: 25173168.
        View in: PubMed
      21. Shaterian A, Saba SC, Yee B, Tokin C, Mailey B, Dobke MK, Wallace A. Single dual-trained surgeon for breast care leads to higher reconstruction rates after mastectomy. World J Surg. 2013 Nov; 37(11):2600-6. PMID: 23963349.
        View in: PubMed
      22. Baker JL, Mailey B, Tokin CA, Blair SL, Wallace A. Postmastectomy reconstruction is associated with improved survival in patients with invasive breast cancer: a single-institution study. Am Surg. 2013 Oct; 79(10):977-81. PMID: 24160782.
        View in: PubMed
      23. Qin Z, Hall DJ, Liss MA, Hoh CK, Kane CJ, Wallace A, Vera DR. Optimization via specific fluorescence brightness of a receptor-targeted probe for optical imaging and positron emission tomography of sentinel lymph nodes. J Biomed Opt. 2013 Oct; 18(10):101315. PMID: 23958947; PMCID: PMC3745642.
        View in: PubMed, PubMed Central
      24. Mailey B, Saba S, Baker J, Tokin C, Hickey S, Wong R, Wallace A, Cohen SR. A comparison of cell-enriched fat transfer to conventional fat grafting after aesthetic procedures using a patient satisfaction survey. Ann Plast Surg. 2013 Apr; 70(4):410-5. PMID: 23486128.
        View in: PubMed
      25. Wallace A, Han LK, Povoski SP, Deck K, Schneebaum S, Hall NC, Hoh CK, Limmer KK, Krontiras H, Frazier TG, Cox C, Avisar E, Faries M, King DW, Christman L, Vera DR. Comparative evaluation of [(99m)tc]tilmanocept for sentinel lymph node mapping in breast cancer patients: results of two phase 3 trials. Ann Surg Oncol. 2013 Aug; 20(8):2590-9. PMID: 23504141; PMCID: PMC3705144.
        View in: PubMed, PubMed Central
      26. Sondak VK, King DW, Zager JS, Schneebaum S, Kim J, Leong SP, Faries MB, Averbook BJ, Martinez SR, Puleo CA, Messina JL, Christman L, Wallace A. Combined analysis of phase III trials evaluating [??mTc]tilmanocept and vital blue dye for identification of sentinel lymph nodes in clinically node-negative cutaneous melanoma. Ann Surg Oncol. 2013 Feb; 20(2):680-8. PMID: 23054107; PMCID: PMC3560941.
        View in: PubMed, PubMed Central
      27. Emerson DK, Limmer KK, Hall DJ, Han SH, Eckelman WC, Kane CJ, Wallace A, Vera DR. A receptor-targeted fluorescent radiopharmaceutical for multireporter sentinel lymph node imaging. Radiology. 2012 Oct; 265(1):186-93. PMID: 22753678; PMCID: PMC3447170.
        View in: PubMed, PubMed Central
      28. Tokin CA, Cope FO, Metz WL, Blue MS, Potter BM, Abbruzzese BC, Hartman RD, Joy MT, King DW, Christman LA, Vera DR, Wallace A. The efficacy of Tilmanocept in sentinel lymph mode mapping and identification in breast cancer patients: a comparative review and meta-analysis of the ??mTc-labeled nanocolloid human serum albumin standard of care. Clin Exp Metastasis. 2012 Oct; 29(7):681-6. PMID: 22729510.
        View in: PubMed
      29. Stroup SP, Kane CJ, Farchshchi-Heydari S, James CM, Davis CH, Wallace A, Hoh CK, Vera DR. Preoperative sentinel lymph node mapping of the prostate using PET/CT fusion imaging and Ga-68-labeled tilmanocept in an animal model. Clin Exp Metastasis. 2012 Oct; 29(7):673-80. PMID: 22714690.
        View in: PubMed
      30. Tokin CA, Wallace A. Breast cancer presenting within or adjacent to the breast implant capsule: a case series and clinical recommendations. Clin Breast Cancer. 2012 Aug; 12(4):296-9. PMID: 22507305.
        View in: PubMed
      31. Wallace A, Hoh CK, Limmer KK, Darrah DD, Schulteis G, Vera DR. Sentinel lymph node accumulation of Lymphoseek and Tc-99m-sulfur colloid using a "2-day" protocol. Nucl Med Biol. 2009 Aug; 36(6):687-92. PMID: 19647175; PMCID: PMC4201841.
        View in: PubMed, PubMed Central
      32. Wallace A, Hoh CK, Darrah DD, Schulteis G, Vera DR. Sentinel lymph node mapping of breast cancer via intradermal administration of Lymphoseek. Nucl Med Biol. 2007 Oct; 34(7):849-53. PMID: 17921035; PMCID: PMC4189800.
        View in: PubMed, PubMed Central
      33. Moore RL, Mungara A, Shayan K, Wallace A. Bilaterally symmetric juvenile fibroadenomas and tubular breast deformity in a prepubescent girl. J Pediatr Surg. 2007 Jun; 42(6):1133-6. PMID: 17560236.
        View in: PubMed
      34. Wallace A, Hoh CK, Ellner SJ, Darrah DD, Schulteis G, Vera DR. Lymphoseek: a molecular imaging agent for melanoma sentinel lymph node mapping. Ann Surg Oncol. 2007 Feb; 14(2):913-21. PMID: 17146742.
        View in: PubMed
      35. Schöder H, Glass EC, Pecking AP, Harness JK, Wallace A, Hirnle P, Alberini JL, Vilain D, Larson SM, Hoh CK, Vera DR. Molecular targeting of the lymphovascular system for imaging and therapy. Cancer Metastasis Rev. 2006 Jun; 25(2):185-201. PMID: 16770532.
        View in: PubMed
      36. Salem CE, Hoh CK, Wallace A, Vera DR. A preclinical study of prostate sentinel lymph node mapping with [99mTC]diethylenetetramine pentaacetic acid-mannosyl-dextran. J Urol. 2006 Feb; 175(2):744-8. PMID: 16407043.
        View in: PubMed
      37. Wallace A, Ellner SJ, Méndez J, Hoh CK, Salem CE, Bosch CM, Orahood RC, Vera DR. Minimally invasive sentinel lymph node mapping of the pig colon with Lymphoseek. Surgery. 2006 Feb; 139(2):217-23. PMID: 16455331.
        View in: PubMed
      38. Wallace A, Comstock C, Hoh CK, Vera DR. Breast imaging: a surgeon's prospective. Nucl Med Biol. 2005 Oct; 32(7):781-92. PMID: 16243654.
        View in: PubMed
      39. Ellner SJ, Méndez J, Vera DR, Hoh CK, Ashburn WL, Wallace A. Sentinel lymph node mapping of the colon and stomach using lymphoseek in a pig model. Ann Surg Oncol. 2004 Jul; 11(7):674-81. PMID: 15231522.
        View in: PubMed
      40. Ellner SJ, Hoh CK, Vera DR, Darrah DD, Schulteis G, Wallace A. Dose-dependent biodistribution of [(99m)Tc]DTPA-mannosyl-dextran for breast cancer sentinel lymph node mapping. Nucl Med Biol. 2003 Nov; 30(8):805-10. PMID: 14698783.
        View in: PubMed
      41. Méndez J, Wallace A, Hoh CK, Vera DR. Detection of gastric and colonic sentinel nodes through endoscopic administration of 99mTc-DTPA-mannosyl-dextran in pigs. J Nucl Med. 2003 Oct; 44(10):1677-81. PMID: 14530486.
        View in: PubMed
      42. Hoh CK, Wallace A, Vera DR. Preclinical studies of [(99m)Tc]DTPA-mannosyl-dextran . Nucl Med Biol. 2003 Jul; 30(5):457-64. PMID: 12831982.
        View in: PubMed
      43. Wallace A, Hoh CK, Vera DR, Darrah DD, Schulteis G. Lymphoseek: a molecular radiopharmaceutical for sentinel node detection. Ann Surg Oncol. 2003 Jun; 10(5):531-8. PMID: 12794019.
        View in: PubMed
      44. Shen J, Wallace A, Bouvet M. The role of sentinel lymph node biopsy for melanoma. Semin Oncol. 2002 Aug; 29(4):341-52. PMID: 12170437.
        View in: PubMed
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