Stephen Wasserman

Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
vCardDownload vCard

    Collapse Biography 
    Collapse Education and Training
    University of California, Los Angeles, Los Angeles, CAMD1968Medicine
    Stanford University, Palo Alto, CAAB1964Biology

    Collapse Overview 
    Collapse Overview
    Research Interests
    -Acute inflammation
    -The role of innate immune molecules in the resolution and persistence of otitis media
    -The clinical problem of asthma

    Collapse Research 
    Collapse Research Activities and Funding
    ASTHMA CLINICAL RESEARCH NETWORK
    NIH U10HL074218Sep 15, 2003 - Dec 31, 2011
    Role: Principal Investigator
    Mechanisms of Persistence and Recovery in Otitis Media
    NIH R01DC006279Jul 1, 2003 - Mar 31, 2017
    Role: Principal Investigator
    EFFICACY OF IMMUNOTHERAPY IN MITE ALLERGIC ASTHMA
    NIH U01AI021991Sep 30, 1984 - Dec 31, 1990
    Role: Principal Investigator
    RELEASE &EFFECT OF MAST CELL/BASOPHIL MEDIATORS
    NIH R01AI017268Jul 1, 1980 - Aug 31, 1990
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A kinase inhibitor screen identifies signaling pathways regulating mucosal growth during otitis media. PLoS One. 2020; 15(8):e0235634. Noel J, Suzukawa K, Chavez E, Pak K, Wasserman SI, Kurabi A, Ryan AF. PMID: 32760078.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    2. Role of the PI3K/AKT pathway and PTEN in otitis media. Exp Cell Res. 2020 02 01; 387(1):111758. Lee HH, Chin A, Pak K, Wasserman SI, Kurabi A, Ryan AF. PMID: 31837294.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media. Innate Immun. 2019 11; 25(8):503-512. Lee J, Leichtle A, Zuckerman E, Pak K, Spriggs M, Wasserman SI, Kurabi A. PMID: 31474163.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    4. Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery. PLoS One. 2018; 13(1):e0190850. Ting JP, Tung F, Antonysamy S, Wasserman S, Jones SB, Zhang FF, Espada A, Broughton H, Chalmers MJ, Woodman ME, Bina HA, Dodge JA, Benach J, Zhang A, Groshong C, Manglicmot D, Russell M, Afshar S. PMID: 29329326.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    5. Otitis Media and Nasopharyngeal Colonization in ccl3-/- Mice. Infect Immun. 2017 11; 85(11). Deniffel D, Nuyen B, Pak K, Suzukawa K, Hung J, Kurabi A, Wasserman SI, Ryan AF. PMID: 28847849.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    6. Obesity's effect on asthma extends to diagnostic criteria. J Allergy Clin Immunol. 2018 03; 141(3):1096-1104. Lugogo N, Green CL, Agada N, Zhang S, Meghdadpour S, Zhou R, Yang S, Anstrom KJ, Israel E, Martin R, Lemanske RF, Boushey H, Lazarus SC, Wasserman SI, Castro M, Calhoun W, Peters SP, DiMango E, Chinchilli V, Kunselman S, King TS, Icitovic N, Kraft M. PMID: 28624608.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
    7. ABAI's MOC Assessment of Knowledge Program Matures: Adding Value with Continuous Learning and Assessment. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):80-83. Bernstein DI, Wasserman SI, Thompson WP, Freeman TM. PMID: 28065344.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    8. Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media. Curr Allergy Asthma Rep. 2016 Jan; 16(1):6. Kurabi A, Pak K, Ryan AF, Wasserman SI. PMID: 26732809.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    9. The transcriptome of a complete episode of acute otitis media. BMC Genomics. 2015 Apr 03; 16:259. Hernandez M, Leichtle A, Pak K, Webster NJ, Wasserman SI, Ryan AF. PMID: 25888408.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansAnimalsCells
    10. C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media. BMC Immunol. 2014 Oct 14; 15:46. Yao W, Frie M, Pan J, Pak K, Webster N, Wasserman SI, Ryan AF. PMID: 25311344.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    11. A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation. PLoS One. 2014; 9(7):e102739. Suzukawa K, Tomlin J, Pak K, Chavez E, Kurabi A, Baird A, Wasserman SI, Ryan AF. PMID: 25033458.
      View in: PubMed   Mentions: 12     Fields:    Translation:Animals
    12. The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media. Innate Immun. 2015 Feb; 21(2):203-14. Kurabi A, Lee J, Wong C, Pak K, Hoffman HM, Ryan AF, Wasserman SI. PMID: 24652041.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    13. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network . PMID: 24084072.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCTClinical Trials
    14. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. PMID: 23541324.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    15. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA, Asthma Clinical Research Network of the National Heart, Lung, and Blood Institute . PMID: 22968888.
      View in: PubMed   Mentions: 37     Fields:    Translation:Humans
    16. Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop. J Allergy Clin Immunol. 2011 Sep; 128(3 Suppl):S4-24. Hanania NA, King MJ, Braman SS, Saltoun C, Wise RA, Enright P, Falsey AR, Mathur SK, Ramsdell JW, Rogers L, Stempel DA, Lima JJ, Fish JE, Wilson SR, Boyd C, Patel KV, Irvin CG, Yawn BP, Halm EA, Wasserman SI, Sands MF, Ershler WB, Ledford DK, Asthma in Elderly workshop participants . PMID: 21872730.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansPHPublic Health
    17. Biologic modulators in allergic and autoinflammatory diseases. Curr Opin Allergy Clin Immunol. 2011 Aug; 11(4):355-60. Broderick L, Tourangeau LM, Kavanaugh A, Wasserman SI. PMID: 21659854.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    18. MOC CME program. Ann Allergy Asthma Immunol. 2011 Aug; 107(2):183. Wasserman SI, Vapniarek LJ. PMID: 21802030.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Maintenance of certification and maintenance of professionalism. J Allergy Clin Immunol. 2011 Sep; 128(3):465-6. Wasserman SI. PMID: 21481445.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. The role of monoclonal antibodies in the treatment of severe asthma. Ther Adv Respir Dis. 2011 Jun; 5(3):183-94. Tourangeau LM, Kavanaugh A, Wasserman SI. PMID: 21393345.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    21. Innate signaling in otitis media: pathogenesis and recovery. Curr Allergy Asthma Rep. 2011 Feb; 11(1):78-84. Leichtle A, Lai Y, Wollenberg B, Wasserman SI, Ryan AF. PMID: 21049294.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    22. TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media. BMC Immunol. 2011 Jan 26; 12:12. Ebmeyer J, Leichtle A, Hernandez M, Ebmeyer U, Husseman J, Pak K, Sudhoff H, Broide D, Wasserman SI, Ryan AF. PMID: 21269505.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansAnimals
    23. The role of DNA sensing and innate immune receptor TLR9 in otitis media. Innate Immun. 2012 Feb; 18(1):3-13. Leichtle A, Hernandez M, Lee J, Pak K, Webster NJ, Wollenberg B, Wasserman SI, Ryan AF. PMID: 21239460.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansAnimalsCells
    24. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol. 2011 Feb; 127(2):372-381.e1-3. Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Wiener-Kronish JP, Sutherland ER, King TS, Icitovic N, Martin RJ, Calhoun WJ, Castro M, Denlinger LC, Dimango E, Kraft M, Peters SP, Wasserman SI, Wechsler ME, Boushey HA, Lynch SV, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network . PMID: 21194740.
      View in: PubMed   Mentions: 257     Fields:    Translation:HumansCells
    25. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):747-53. Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ, National Heart, Lung and Blood Institute's Asthma Clinical Research Network . PMID: 20920764.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    26. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER, National Heart, Lung, and Blood Institute Asthma Clinical Research Network . PMID: 20979471.
      View in: PubMed   Mentions: 119     Fields:    Translation:Humans
    27. Molecular determinants of T cell epitope recognition to the common Timothy grass allergen. J Immunol. 2010 Jul 15; 185(2):943-55. Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A. PMID: 20554959.
      View in: PubMed   Mentions: 84     Fields:    Translation:HumansAnimalsCells
    28. CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice. J Immunol. 2010 Mar 15; 184(6):3087-97. Leichtle A, Hernandez M, Ebmeyer J, Yamasaki K, Lai Y, Radek K, Choung YH, Euteneuer S, Pak K, Gallo R, Wasserman SI, Ryan AF. PMID: 20164426.
      View in: PubMed   Mentions: 23     Fields:    Translation:AnimalsCells
    29. Reconstitution of the mast cell population in W/Wv mice. Otol Neurotol. 2010 Jan; 31(1):42-7. Ebmeyer J, Ebmeyer U, Pak K, Sudhoff H, Broide D, Ryan AF, Wasserman S. PMID: 19752767.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    30. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009 Nov 21; 374(9703):1754-64. Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E, National Heart, Lung and Blood Institute's Asthma Clinical Research Network . PMID: 19932356.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    31. The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery. BMC Immunol. 2009 Aug 05; 10:45. Leichtle A, Hernandez M, Pak K, Webster NJ, Wasserman SI, Ryan AF. PMID: 19656404.
      View in: PubMed   Mentions: 17     Fields:    Translation:AnimalsCells
    32. TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media. Innate Immun. 2009 Aug; 15(4):205-15. Leichtle A, Hernandez M, Pak K, Yamasaki K, Cheng CF, Webster NJ, Ryan AF, Wasserman SI. PMID: 19586996.
      View in: PubMed   Mentions: 38     Fields:    Translation:HumansAnimalsCells
    33. Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis. 2008 Dec 15; 198(12):1862-9. Hernandez M, Leichtle A, Pak K, Ebmeyer J, Euteneuer S, Obonyo M, Guiney DG, Webster NJ, Broide DH, Ryan AF, Wasserman SI. PMID: 18986247.
      View in: PubMed   Mentions: 37     Fields:    Translation:AnimalsCells
    34. Aeroallergen sensitization correlates with PC(20) and exhaled nitric oxide in subjects with mild-to-moderate asthma. J Allergy Clin Immunol. 2008 Mar; 121(3):671-7. Craig TJ, King TS, Lemanske RF, Wechsler ME, Icitovic N, Zimmerman RR, Wasserman S, National Heart, Lung, and Blood Institute's Asthma Clinical Research Network . PMID: 18234311.
      View in: PubMed   Mentions: 17     Fields:    Translation:Humans
    35. The allergy archives: pioneer and milestones. The discovery and characterization of the leukotrienes. J Allergy Clin Immunol. 2006 Oct; 118(4):972-80. Serhan CN, Wasserman SI. PMID: 17073024.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimals
    36. Rosuvastatin: an independent analysis of risks and benefits. MedGenMed. 2006 Jun 14; 8(2):73. Zipes DP, Zvaifler NJ, Glassock RJ, Gilman S, Muñoz A, Gogolak V, Gordis L, Dedon PC, Guengerich FP, Wasserman SI, Witztum JL, Wogan GN. PMID: 16926812.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    37. Mouse models of induced otitis media. Brain Res. 2006 May 26; 1091(1):3-8. Ryan AF, Ebmeyer J, Furukawa M, Pak K, Melhus A, Wasserman SI, Chung WH. PMID: 16764829.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimals
    38. Biologic therapies for the treatment of asthma. Clin Chest Med. 2006 Mar; 27(1):133-47, vii. Wagelie-Steffen AL, Kavanaugh AF, Wasserman SI. PMID: 16543058.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    39. Role of mast cells in otitis media. J Allergy Clin Immunol. 2005 Nov; 116(5):1129-35. Ebmeyer J, Furukawa M, Pak K, Ebmeyer U, Sudhoff H, Broide D, Ryan AF, Wasserman S. PMID: 16275387.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    40. 31. Assessment of clinical competence of the allergist/immunologist. J Allergy Clin Immunol. 2003 Feb; 111(2 Suppl):S774-8. Wasserman SI. PMID: 12592322.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    41. The role of transcription factors in allergic inflammation. J Allergy Clin Immunol. 2002 Oct; 110(4):553-64. Escoubet-Lozach L, Glass CK, Wasserman SI. PMID: 12373260.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimals
    Stephen's Networks
    Concepts (250)
    Derived automatically from this person's publications.
    _
    Co-Authors (19)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _