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Stephen Wasserman

Title(s)Emeritus Professor, Medicine
SchoolHealth Sciences
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    Collapse Biography 
    Collapse Education and Training
    University of California, Los Angeles, Los Angeles, CAMD1968Medicine
    Stanford University, Palo Alto, CAAB1964Biology

    Collapse Overview 
    Collapse Overview
    Research Interests
    -Acute inflammation
    -The role of innate immune molecules in the resolution and persistence of otitis media
    -The clinical problem of asthma

    Collapse Research 
    Collapse Research Activities and Funding
    ASTHMA CLINICAL RESEARCH NETWORK
    NIH/NHLBI U10HL074218Sep 15, 2003 - Dec 31, 2011
    Role: Principal Investigator
    Mechanisms of Persistence and Recovery in Otitis Media
    NIH/NIDCD R01DC006279Jul 1, 2003 - Mar 31, 2015
    Role: Principal Investigator
    EFFICACY OF IMMUNOTHERAPY IN MITE ALLERGIC ASTHMA
    NIH/NIAID U01AI021991Sep 30, 1984 - Dec 31, 1990
    Role: Principal Investigator
    RELEASE &EFFECT OF MAST CELL/BASOPHIL MEDIATORS
    NIH/NIAID R01AI017268Jul 1, 1980 - Aug 31, 1990
    Role: Principal Investigator

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    Collapse Clinical Trials
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    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Lee J, Leichtle A, Zuckerman E, Pak K, Spriggs M, Wasserman SI, Kurabi A. NOD1/NOD2-mediated recognition of non-typeable Haemophilus influenzae activates innate immunity during otitis media. Innate Immun. 2019 Aug 31; 1753425919872266. PMID: 31474163.
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    2. Ting JP, Tung F, Antonysamy S, Wasserman S, Jones SB, Zhang FF, Espada A, Broughton H, Chalmers MJ, Woodman ME, Bina HA, Dodge JA, Benach J, Zhang A, Groshong C, Manglicmot D, Russell M, Afshar S. Utilization of peptide phage display to investigate hotspots on IL-17A and what it means for drug discovery. PLoS One. 2018; 13(1):e0190850. PMID: 29329326.
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    3. Deniffel D, Nuyen B, Pak K, Suzukawa K, Hung J, Kurabi A, Wasserman SI, Ryan AF. Otitis Media and Nasopharyngeal Colonization in ccl3-/- Mice. Infect Immun. 2017 11; 85(11). PMID: 28847849.
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    4. Lugogo N, Green CL, Agada N, Zhang S, Meghdadpour S, Zhou R, Yang S, Anstrom KJ, Israel E, Martin R, Lemanske RF, Boushey H, Lazarus SC, Wasserman SI, Castro M, Calhoun W, Peters SP, DiMango E, Chinchilli V, Kunselman S, King TS, Icitovic N, Kraft M. Obesity's effect on asthma extends to diagnostic criteria. J Allergy Clin Immunol. 2018 Mar; 141(3):1096-1104. PMID: 28624608.
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    5. Bernstein DI, Wasserman SI, Thompson WP, Freeman TM. ABAI's MOC Assessment of Knowledge Program Matures: Adding Value with Continuous Learning and Assessment. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):80-83. PMID: 28065344.
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    6. Kurabi A, Pak K, Ryan AF, Wasserman SI. Innate Immunity: Orchestrating Inflammation and Resolution of Otitis Media. Curr Allergy Asthma Rep. 2016 Jan; 16(1):6. PMID: 26732809.
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    7. Hernandez M, Leichtle A, Pak K, Webster NJ, Wasserman SI, Ryan AF. The transcriptome of a complete episode of acute otitis media. BMC Genomics. 2015 Apr 03; 16:259. PMID: 25888408; PMCID: PMC4394589.
    8. Yao W, Frie M, Pan J, Pak K, Webster N, Wasserman SI, Ryan AF. C-Jun N-terminal kinase (JNK) isoforms play differing roles in otitis media. BMC Immunol. 2014 Oct 14; 15:46. PMID: 25311344; PMCID: PMC4200133.
    9. Suzukawa K, Tomlin J, Pak K, Chavez E, Kurabi A, Baird A, Wasserman SI, Ryan AF. A mouse model of otitis media identifies HB-EGF as a mediator of inflammation-induced mucosal proliferation. PLoS One. 2014; 9(7):e102739. PMID: 25033458; PMCID: PMC4102546.
    10. Kurabi A, Lee J, Wong C, Pak K, Hoffman HM, Ryan AF, Wasserman SI. The inflammasome adaptor ASC contributes to multiple innate immune processes in the resolution of otitis media. Innate Immun. 2015 Feb; 21(2):203-14. PMID: 24652041; PMCID: PMC4379507.
    11. Peters SP, Bleecker ER, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger LC, Engle LL, Dimango EA, Israel E, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Szefler SJ. Predictors of response to tiotropium versus salmeterol in asthmatic adults. J Allergy Clin Immunol. 2013 Nov; 132(5):1068-1074.e1. PMID: 24084072; PMCID: PMC3826080.
    12. Li X, Hawkins GA, Ampleford EJ, Moore WC, Li H, Hastie AT, Howard TD, Boushey HA, Busse WW, Calhoun WJ, Castro M, Erzurum SC, Israel E, Lemanske RF, Szefler SJ, Wasserman SI, Wenzel SE, Peters SP, Meyers DA, Bleecker ER. Genome-wide association study identifies TH1 pathway genes associated with lung function in asthmatic patients. J Allergy Clin Immunol. 2013 Aug; 132(2):313-20.e15. PMID: 23541324.
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    13. Calhoun WJ, Ameredes BT, King TS, Icitovic N, Bleecker ER, Castro M, Cherniack RM, Chinchilli VM, Craig T, Denlinger L, DiMango EA, Engle LL, Fahy JV, Grant JA, Israel E, Jarjour N, Kazani SD, Kraft M, Kunselman SJ, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Moore WC, Pascual R, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Boushey HA. Comparison of physician-, biomarker-, and symptom-based strategies for adjustment of inhaled corticosteroid therapy in adults with asthma: the BASALT randomized controlled trial. JAMA. 2012 Sep 12; 308(10):987-97. PMID: 22968888; PMCID: PMC3697088.
    14. Hanania NA, King MJ, Braman SS, Saltoun C, Wise RA, Enright P, Falsey AR, Mathur SK, Ramsdell JW, Rogers L, Stempel DA, Lima JJ, Fish JE, Wilson SR, Boyd C, Patel KV, Irvin CG, Yawn BP, Halm EA, Wasserman SI, Sands MF, Ershler WB, Ledford DK. Asthma in the elderly: Current understanding and future research needs--a report of a National Institute on Aging (NIA) workshop. J Allergy Clin Immunol. 2011 Sep; 128(3 Suppl):S4-24. PMID: 21872730; PMCID: PMC3164961.
    15. Broderick L, Tourangeau LM, Kavanaugh A, Wasserman SI. Biologic modulators in allergic and autoinflammatory diseases. Curr Opin Allergy Clin Immunol. 2011 Aug; 11(4):355-60. PMID: 21659854; PMCID: PMC3154953.
    16. Wasserman SI, Vapniarek LJ. MOC CME program. Ann Allergy Asthma Immunol. 2011 Aug; 107(2):183. PMID: 21802030.
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    17. Wasserman SI. Maintenance of certification and maintenance of professionalism. J Allergy Clin Immunol. 2011 Sep; 128(3):465-6. PMID: 21481445.
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    18. Tourangeau LM, Kavanaugh A, Wasserman SI. The role of monoclonal antibodies in the treatment of severe asthma. Ther Adv Respir Dis. 2011 Jun; 5(3):183-94. PMID: 21393345.
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    19. Leichtle A, Lai Y, Wollenberg B, Wasserman SI, Ryan AF. Innate signaling in otitis media: pathogenesis and recovery. Curr Allergy Asthma Rep. 2011 Feb; 11(1):78-84. PMID: 21049294; PMCID: PMC3020300.
    20. Ebmeyer J, Leichtle A, Hernandez M, Ebmeyer U, Husseman J, Pak K, Sudhoff H, Broide D, Wasserman SI, Ryan AF. TNFA deletion alters apoptosis as well as caspase 3 and 4 expression during otitis media. BMC Immunol. 2011 Jan 26; 12:12. PMID: 21269505; PMCID: PMC3040143.
    21. Leichtle A, Hernandez M, Lee J, Pak K, Webster NJ, Wollenberg B, Wasserman SI, Ryan AF. The role of DNA sensing and innate immune receptor TLR9 in otitis media. Innate Immun. 2012 Feb; 18(1):3-13. PMID: 21239460; PMCID: PMC4041324.
    22. Huang YJ, Nelson CE, Brodie EL, Desantis TZ, Baek MS, Liu J, Woyke T, Allgaier M, Bristow J, Wiener-Kronish JP, Sutherland ER, King TS, Icitovic N, Martin RJ, Calhoun WJ, Castro M, Denlinger LC, Dimango E, Kraft M, Peters SP, Wasserman SI, Wechsler ME, Boushey HA, Lynch SV. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol. 2011 Feb; 127(2):372-381.e1-3. PMID: 21194740; PMCID: PMC3037020.
    23. Sutherland ER, King TS, Icitovic N, Ameredes BT, Bleecker E, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Chinchilli VM, Craig TJ, Denlinger L, DiMango EA, Fahy JV, Israel E, Jarjour N, Kraft M, Lazarus SC, Lemanske RF, Peters SP, Ramsdell J, Sorkness CA, Szefler SJ, Walter MJ, Wasserman SI, Wechsler ME, Chu HW, Martin RJ. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol. 2010 Oct; 126(4):747-53. PMID: 20920764; PMCID: PMC2950827.
    24. Peters SP, Kunselman SJ, Icitovic N, Moore WC, Pascual R, Ameredes BT, Boushey HA, Calhoun WJ, Castro M, Cherniack RM, Craig T, Denlinger L, Engle LL, DiMango EA, Fahy JV, Israel E, Jarjour N, Kazani SD, Kraft M, Lazarus SC, Lemanske RF, Lugogo N, Martin RJ, Meyers DA, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Walter MJ, Wechsler ME, Chinchilli VM, Bleecker ER. Tiotropium bromide step-up therapy for adults with uncontrolled asthma. N Engl J Med. 2010 Oct 28; 363(18):1715-26. PMID: 20979471.
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    25. Oseroff C, Sidney J, Kotturi MF, Kolla R, Alam R, Broide DH, Wasserman SI, Weiskopf D, McKinney DM, Chung JL, Petersen A, Grey H, Peters B, Sette A. Molecular determinants of T cell epitope recognition to the common Timothy grass allergen. J Immunol. 2010 Jul 15; 185(2):943-55. PMID: 20554959.
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    26. Leichtle A, Hernandez M, Ebmeyer J, Yamasaki K, Lai Y, Radek K, Choung YH, Euteneuer S, Pak K, Gallo R, Wasserman SI, Ryan AF. CC chemokine ligand 3 overcomes the bacteriocidal and phagocytic defect of macrophages and hastens recovery from experimental otitis media in TNF-/- mice. J Immunol. 2010 Mar 15; 184(6):3087-97. PMID: 20164426; PMCID: PMC2929161.
    27. Ebmeyer J, Ebmeyer U, Pak K, Sudhoff H, Broide D, Ryan AF, Wasserman S. Reconstitution of the mast cell population in W/Wv mice. Otol Neurotol. 2010 Jan; 31(1):42-7. PMID: 19752767; PMCID: PMC2796298.
    28. Wechsler ME, Kunselman SJ, Chinchilli VM, Bleecker E, Boushey HA, Calhoun WJ, Ameredes BT, Castro M, Craig TJ, Denlinger L, Fahy JV, Jarjour N, Kazani S, Kim S, Kraft M, Lazarus SC, Lemanske RF, Markezich A, Martin RJ, Permaul P, Peters SP, Ramsdell J, Sorkness CA, Sutherland ER, Szefler SJ, Walter MJ, Wasserman SI, Israel E. Effect of beta2-adrenergic receptor polymorphism on response to longacting beta2 agonist in asthma (LARGE trial): a genotype-stratified, randomised, placebo-controlled, crossover trial. Lancet. 2009 Nov 21; 374(9703):1754-64. PMID: 19932356; PMCID: PMC2914569.
    29. Leichtle A, Hernandez M, Pak K, Webster NJ, Wasserman SI, Ryan AF. The toll-Like receptor adaptor TRIF contributes to otitis media pathogenesis and recovery. BMC Immunol. 2009 Aug 05; 10:45. PMID: 19656404; PMCID: PMC2736931.
    30. Leichtle A, Hernandez M, Pak K, Yamasaki K, Cheng CF, Webster NJ, Ryan AF, Wasserman SI. TLR4-mediated induction of TLR2 signaling is critical in the pathogenesis and resolution of otitis media. Innate Immun. 2009 Aug; 15(4):205-15. PMID: 19586996; PMCID: PMC3565845.
    31. Hernandez M, Leichtle A, Pak K, Ebmeyer J, Euteneuer S, Obonyo M, Guiney DG, Webster NJ, Broide DH, Ryan AF, Wasserman SI. Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis. 2008 Dec 15; 198(12):1862-9. PMID: 18986247; PMCID: PMC3584630.
    32. Walter MJ, Castro M, Kunselman SJ, Chinchilli VM, Reno M, Ramkumar TP, Avila PC, Boushey HA, Ameredes BT, Bleecker ER, Calhoun WJ, Cherniack RM, Craig TJ, Denlinger LC, Israel E, Fahy JV, Jarjour NN, Kraft M, Lazarus SC, Lemanske RF, Martin RJ, Peters SP, Ramsdell JW, Sorkness CA, Sutherland ER, Szefler SJ, Wasserman SI, Wechsler ME. Predicting worsening asthma control following the common cold. Eur Respir J. 2008 Dec; 32(6):1548-54. PMID: 18768579.
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    33. Craig TJ, King TS, Lemanske RF, Wechsler ME, Icitovic N, Zimmerman RR, Wasserman S. Aeroallergen sensitization correlates with PC(20) and exhaled nitric oxide in subjects with mild-to-moderate asthma. J Allergy Clin Immunol. 2008 Mar; 121(3):671-7. PMID: 18234311.
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    34. Serhan CN, Wasserman SI. The allergy archives: pioneer and milestones. The discovery and characterization of the leukotrienes. J Allergy Clin Immunol. 2006 Oct; 118(4):972-80. PMID: 17073024.
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    35. Zipes DP, Zvaifler NJ, Glassock RJ, Gilman S, Muñoz A, Gogolak V, Gordis L, Dedon PC, Guengerich FP, Wasserman SI, Witztum JL, Wogan GN. Rosuvastatin: an independent analysis of risks and benefits. MedGenMed. 2006 Jun 14; 8(2):73. PMID: 16926812; PMCID: PMC1785157.
    36. Ryan AF, Ebmeyer J, Furukawa M, Pak K, Melhus A, Wasserman SI, Chung WH. Mouse models of induced otitis media. Brain Res. 2006 May 26; 1091(1):3-8. PMID: 16764829.
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    37. Wagelie-Steffen AL, Kavanaugh AF, Wasserman SI. Biologic therapies for the treatment of asthma. Clin Chest Med. 2006 Mar; 27(1):133-47, vii. PMID: 16543058.
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    38. Ebmeyer J, Furukawa M, Pak K, Ebmeyer U, Sudhoff H, Broide D, Ryan AF, Wasserman S. Role of mast cells in otitis media. J Allergy Clin Immunol. 2005 Nov; 116(5):1129-35. PMID: 16275387.
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    39. Wasserman SI. 31. Assessment of clinical competence of the allergist/immunologist. J Allergy Clin Immunol. 2003 Feb; 111(2 Suppl):S774-8. PMID: 12592322.
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    40. Escoubet-Lozach L, Glass CK, Wasserman SI. The role of transcription factors in allergic inflammation. J Allergy Clin Immunol. 2002 Oct; 110(4):553-64. PMID: 12373260.
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    41. Wasserman SI, Kimball HR, Duffy FD. Recertification in internal medicine: a program of continuous professional development. Task Force on Recertification. Ann Intern Med. 2000 Aug 01; 133(3):202-8. PMID: 10906835.
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    42. Wasserman SI, Kimball H. Continuous professional development in internal medicine: recertification as a measure of professional accountability and quality improvement. Trans Am Clin Climatol Assoc. 2000; 111:294-7; discussion 297-9. PMID: 10881347.
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    43. Wasserman SI. The allergist in the new millennium. J Allergy Clin Immunol. 2000 Jan; 105(1 Pt 1):3-8. PMID: 10629446.
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    44. Wasserman SI, Kemp JP, Rachelefsky GS, Fireman P, Shapiro GG, Busse WW. Inhaled corticosteroids and likelihood of cataract extraction. JAMA. 1999 Mar 03; 281(9):791-2; author reply 792-3. PMID: 10070990.
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    45. Ries AL, Picchi MA, Nguyen LH, Moser RJ, Molgaard CA, Wasserman SI. Asthma in a Vietnamese refugee population. Am J Respir Crit Care Med. 1997 Jun; 155(6):1895-901. PMID: 9196092.
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    46. Rose G, Arlian L, Bernstein D, Grant A, Lopez M, Metzger J, Wasserman S, Platts-Mills TA. Evaluation of household dust mite exposure and levels of specific IgE and IgG antibodies in asthmatic patients enrolled in a trial of immunotherapy. J Allergy Clin Immunol. 1996 May; 97(5):1071-8. PMID: 8626984.
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    47. Wasserman SI, Austen KF, Lockey RF. Board requirements versus National Institutes of Health requirements. J Allergy Clin Immunol. 1996 Mar; 97(3):871-5. PMID: 8613649.
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    48. Wasserman SI, Gross GN, Schoenwetter WF, Munk ZM, Kral KM, Schaberg A, Kellerman DJ. A 12-week dose-ranging study of fluticasone propionate powder in the treatment of asthma. J Asthma. 1996; 33(4):265-74. PMID: 8707781.
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    49. Wasserman SI. Immunopharmacologic profile of nedocromil sodium. Allergy Proc. 1995 Mar-Apr; 16(2):67-71. PMID: 7797061.
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    50. Wasserman SI, Furukawa CT, Henochowicz SI, Marcoux JP, Prenner BM, Findlay SR, Gross GN, Hudson LD, Myers DJ, Steinberg P. Asthma symptoms and airway hyperresponsiveness are lower during treatment with nedocromil sodium than during treatment with regular inhaled albuterol. J Allergy Clin Immunol. 1995 Feb; 95(2):541-7. PMID: 7852670.
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    51. Wasserman SI. Mast cells and airway inflammation in asthma. Am J Respir Crit Care Med. 1994 Nov; 150(5 Pt 2):S39-41. PMID: 7952590.
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    52. Wasserman SI. A review of some recent clinical studies with nedocromil sodium. J Allergy Clin Immunol. 1993 Jul; 92(1 Pt 2):210-5. PMID: 8101535.
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    53. Kreiss K, Wasserman S, Mroz MM, Newman LS. Beryllium disease screening in the ceramics industry. Blood lymphocyte test performance and exposure-disease relations. J Occup Med. 1993 Mar; 35(3):267-74. PMID: 8455096.
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    54. Broide DH, Lotz M, Cuomo AJ, Coburn DA, Federman EC, Wasserman SI. Cytokines in symptomatic asthma airways. J Allergy Clin Immunol. 1992 May; 89(5):958-67. PMID: 1374772.
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    55. Wasserman SI, Broide DH, Marquardt DL. Cetirizine therapy for seasonal allergic rhinitis: alternative dosage schedules. Clin Ther. 1991 Nov-Dec; 13(6):707-13. PMID: 1686422.
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    56. Broide DH, Gleich GJ, Cuomo AJ, Coburn DA, Federman EC, Schwartz LB, Wasserman SI. Evidence of ongoing mast cell and eosinophil degranulation in symptomatic asthma airway. J Allergy Clin Immunol. 1991 Oct; 88(4):637-48. PMID: 1717532.
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    57. Catanzaro A, Ryan A, Batcher S, Wasserman SI. The response to human rIL-1, rIL-2, and rTNF in the middle ear of guinea pigs. Laryngoscope. 1991 Mar; 101(3):271-5. PMID: 2000014.
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    58. Falliers CJ, Brandon ML, Buchman E, Connell JT, Dockhorn R, Leese PT, Miller J, Wasserman SI, Zeterberg JM, Altman R. Double-blind comparison of cetirizine and placebo in the treatment of seasonal rhinitis. Ann Allergy. 1991 Mar; 66(3):257-62. PMID: 1672494.
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    59. Rossi GL, Young DJ, Wasserman SI, Barrett KE. Calcium mobilization in activated mast cells monitored by flow cytometric analysis. Agents Actions. 1990 Nov; 31(3-4):257-62. PMID: 2085141.
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    60. Wasserman SI. Mast cell biology. J Allergy Clin Immunol. 1990 Oct; 86(4 Pt 2):590-3. PMID: 2229821.
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    61. Broide DH, Smith CM, Wasserman SI. Mast cells and pulmonary fibrosis. Identification of a histamine releasing factor in bronchoalveolar lavage fluid. J Immunol. 1990 Sep 15; 145(6):1838-44. PMID: 1697311.
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    62. Insel PA, Wasserman SI. Asthma: a disorder of adrenergic receptors? FASEB J. 1990 Jul; 4(10):2732-6. PMID: 2197153.
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    63. Barrett KE, Cohn JA, Huott PA, Wasserman SI, Dharmsathaphorn K. Immune-related intestinal chloride secretion. II. Effect of adenosine on T84 cell line. Am J Physiol. 1990 May; 258(5 Pt 1):C902-12. PMID: 2159233.
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    64. Glover RA, Bailey CS, Barrett KE, Wasserman SI, Gigli I. Histamine release from rodent and human mast cells induced by protoporphyrin and ultraviolet light: studies of the mechanism of mast-cell activation in erythropoietic protoporphyria. Br J Dermatol. 1990 Apr; 122(4):501-12. PMID: 2337518.
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    65. Broide DH, Eisman S, Ramsdell JW, Ferguson P, Schwartz LB, Wasserman SI. Airway levels of mast cell-derived mediators in exercise-induced asthma. Am Rev Respir Dis. 1990 Mar; 141(3):563-8. PMID: 1689974.
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    66. Wasserman SI. Mast cell-mediated inflammation in asthma. Ann Allergy. 1989 Dec; 63(6 Pt 2):546-50. PMID: 2688493.
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    67. Broide DH, Wasserman SI, Alvaro-Gracia J, Zvaifler NJ, Firestein GS. Transforming growth factor-beta 1 selectively inhibits IL-3-dependent mast cell proliferation without affecting mast cell function or differentiation. J Immunol. 1989 Sep 01; 143(5):1591-7. PMID: 2527268.
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    68. Barrett KE, Huott PA, Shah SS, Dharmsathaphorn K, Wasserman SI. Differing effects of apical and basolateral adenosine on colonic epithelial cell line T84. Am J Physiol. 1989 Jan; 256(1 Pt 1):C197-203. PMID: 2536228.
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    69. Wasserman SI, Marquardt DL, Broide D, Walker L, Barrett K. Characterization, activation, and functional importance of mucosal mast cells. Prog Clin Biol Res. 1989; 297:155-61; discussion 161. PMID: 2685819.
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    70. Goldstein SM, Wasserman SI, Wintroub BU. Mast cell and eosinophil mediated damage in bullous pemphigoid. Immunol Ser. 1989; 46:527-45. PMID: 2484955.
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    71. Broide DH, Metcalfe DD, Wasserman SI. Functional and biochemical characterization of rat bone marrow derived mast cells. J Immunol. 1988 Dec 15; 141(12):4298-305. PMID: 2974057.
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    72. Wasserman SI. Platelet-activating factor as a mediator of bronchial asthma. Hosp Pract (Off Ed). 1988 Nov 15; 23(11):49-58. PMID: 3053741.
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    73. Wasserman SI. Basic mechanisms in asthma. Ann Allergy. 1988 May; 60(5):477-82. PMID: 3163472.
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    74. Wasserman SI, Barrett KE, Huott PA, Beuerlein G, Kagnoff MF, Dharmsathaphorn K. Immune-related intestinal Cl- secretion. I. Effect of histamine on the T84 cell line. Am J Physiol. 1988 Jan; 254(1 Pt 1):C53-62. PMID: 3337221.
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    75. Wasserman SI. Histamine and the preclinical pharmacology of cetirizine. Ann Allergy. 1987 Dec; 59(6 Pt 2):1-3. PMID: 2892442.
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    76. Wasserman SI. The regulation of inflammatory mediator production by mast cell products. Am Rev Respir Dis. 1987 Jun; 135(6 Pt 2):S46-8. PMID: 3592417.
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    77. Lim HW, Gigli I, Wasserman SI. Differential effects of protoporphyrin and uroporphyrin on murine mast cells. J Invest Dermatol. 1987 Mar; 88(3):281-6. PMID: 3102621.
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    78. Marquardt DL, Gruber HE, Wasserman SI. Aminophylline exposure alters mouse bone marrow-derived mast cell adenosine responsiveness. J Allergy Clin Immunol. 1986 Sep; 78(3 Pt 1):462-9. PMID: 3020110.
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    79. Ryan AF, Catanzaro A, Wasserman SI, Harris JP, Vogel CW. The effect of complement depletion on immunologically mediated middle ear effusion and inflammation. Clin Immunol Immunopathol. 1986 Sep; 40(3):410-21. PMID: 3731540.
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    80. Wanderer AA, Grandel KE, Wasserman SI, Farr RS. Clinical characteristics of cold-induced systemic reactions in acquired cold urticaria syndromes: recommendations for prevention of this complication and a proposal for a diagnostic classification of cold urticaria. J Allergy Clin Immunol. 1986 Sep; 78(3 Pt 1):417-23. PMID: 3760401.
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    81. Metzger WJ, Richerson HB, Wasserman SI. Generation and partial characterization of eosinophil chemotactic activity and neutrophil chemotactic activity during early and late-phase asthmatic response. J Allergy Clin Immunol. 1986 Aug; 78(2):282-90. PMID: 3734281.
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    82. Marquardt DL, Walker LL, Wasserman SI. Cromolyn inhibition of mediator release in mast cells derived from mouse bone marrow. Am Rev Respir Dis. 1986 Jun; 133(6):1105-9. PMID: 2940951.
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    83. Wasserman SI. The heart in anaphylaxis. J Allergy Clin Immunol. 1986 May; 77(5):663-6. PMID: 3700887.
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    84. Ryan AF, Catanzaro A, Wasserman SI, Harris JP. Secondary immune response in the middle ear: immunological, morphological, and physiological observations. Ann Otol Rhinol Laryngol. 1986 May-Jun; 95(3 Pt 1):242-9. PMID: 3717850.
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    85. Wasserman SI. The mast cell and theophylline in asthma. Am J Med. 1985 Dec 20; 79(6A):22-5. PMID: 3002176.
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    86. Marquardt DL, Wasserman SI. [3H]Adenosine binding to rat mast cells--pharmacologic and functional characterization. Agents Actions. 1985 Sep; 16(6):453-61. PMID: 3000151.
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    87. Grandel KE, Farr RS, Wanderer AA, Eisenstadt TC, Wasserman SI. Association of platelet-activating factor with primary acquired cold urticaria. N Engl J Med. 1985 Aug 15; 313(7):405-9. PMID: 2410790.
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    88. Wasserman SI. Future pharmacologic agents and maneuvers in asthma therapy. J Allergy Clin Immunol. 1985 Aug; 76(2 Pt 2):405-8. PMID: 2991360.
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    89. Boisvert P, Wasserman SI, Schiff M, Ryan AF. Histamine-induced middle ear effusion and mucosal histopathology in the guinea pig. Ann Otol Rhinol Laryngol. 1985 Mar-Apr; 94(2 Pt 1):212-6. PMID: 3994241.
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    90. Ryan AF, Harris JP, Catanzaro A, Wasserman SI. The role of eustachian tube dysfunction in immune-mediated middle ear effusion and inflammation. Auris Nasus Larynx. 1985; 12 Suppl 1:S203-5. PMID: 3835908.
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    91. Wasserman SI. Mast cell mediators in the blood of patients with asthma. Chest. 1985 Jan; 87(1 Suppl):13S-15S. PMID: 3880526.
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    92. Marquardt DL, Gruber HE, Wasserman SI. Adenosine release from stimulated mast cells. Proc Natl Acad Sci U S A. 1984 Oct; 81(19):6192-6. PMID: 6435127.
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    93. Wasserman SI, Ginsberg MH. Release of platelet factor 4 into the blood after cold challenge of patients with cold urticaria. J Allergy Clin Immunol. 1984 Sep; 74(3 Pt 1):275-9. PMID: 6470362.
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    94. Marquardt DL, Walker LL, Wasserman SI. Adenosine receptors on mouse bone marrow-derived mast cells: functional significance and regulation by aminophylline. J Immunol. 1984 Aug; 133(2):932-7. PMID: 6330205.
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    95. Wasserman SI. The human lung mast cell. Environ Health Perspect. 1984 Apr; 55:259-69. PMID: 6428878.
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    96. Metcalfe DD, Bland CE, Wasserman SI. Biochemical and functional characterization of proteoglycans isolated from basophils of patients with chronic myelogenous leukemia. J Immunol. 1984 Apr; 132(4):1943-50. PMID: 6199418.
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    97. Wesselius LJ, Catanzaro A, Wasserman SI. Neutrophil chemotactic activity generation by alveolar macrophages after bleomycin injury. Am Rev Respir Dis. 1984 Mar; 129(3):485-90. PMID: 6200017.
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    98. Markman M, Howell SB, King M, Pfeifle C, Wasserman SI. Anaphylactic reaction to cytarabine: in vitro evidence that the response is immunoglobulin E mediated. Med Pediatr Oncol. 1984; 12(3):201-3. PMID: 6727776.
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    99. Ruzicka T, Wasserman SI, Soter NA, Printz MP. Inhibition of rat mast cell arachidonic acid cyclooxygenase by dapsone. J Allergy Clin Immunol. 1983 Oct; 72(4):365-70. PMID: 6413566.
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    100. Atkins PC, Wasserman SI. Chemotactic mediators. Clin Rev Allergy. 1983 Sep; 1(3):385-95. PMID: 6370407.
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    101. Wasserman SI. Mediators of immediate hypersensitivity. J Allergy Clin Immunol. 1983 Aug; 72(2):101-19. PMID: 6193157.
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    102. Marquardt DL, Wasserman SI. Modulation of rat serosal mast cell biochemistry by in vivo dexamethasone administration. J Immunol. 1983 Aug; 131(2):934-9. PMID: 6306110.
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    103. Marquardt DL, Wasserman SI. Characterization of the rat mast cell beta-adrenergic receptor in resting and stimulated cells by radioligand binding. J Immunol. 1982 Nov; 129(5):2122-7. PMID: 6126501.
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    104. Marquardt DL, Motulsky HJ, Wasserman SI. Rat lung cholinergic receptor: characterization and regulation by corticosteroids. J Appl Physiol Respir Environ Exerc Physiol. 1982 Sep; 53(3):731-6. PMID: 7129997.
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    105. Marquardt DL, Wasserman SI. Mast cells in allergic diseases and mastocytosis. West J Med. 1982 Sep; 137(3):195-212. PMID: 6293204.
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    106. Lee TC, Malone B, Wasserman SI, Fitzgerald V, Snyder F. Activities of enzymes that metabolize platelet-activating factor (1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine) in neutrophils and eosinophils from humans and the effect of a calcium ionophore. Biochem Biophys Res Commun. 1982 Apr 29; 105(4):1303-8. PMID: 6808993.
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    107. Metcalfe DD, Litvin J, Wasserman SI. The isolation, identification and characterization of sulfated glycosaminoglycans synthesized in vitro by human eosinophils. Biochim Biophys Acta. 1982 Apr 13; 715(2):196-204. PMID: 6803845.
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    108. Schwartz LB, Riedel C, Caulfield JP, Wasserman SI, Austen KF. Cell association of complexes of chymase, heparin proteoglycan, and protein after degranulation by rat mast cells. J Immunol. 1981 Jun; 126(6):2071-8. PMID: 6164718.
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    109. Wasserman SI. The role of neutrophils in asthma. Allergol Immunopathol (Madr). 1981; Suppl 9:35-6. PMID: 6762078.
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    110. Soter NA, Wasserman SI. Physical urticaria/angioedema: an experimental model of mast cell activation in humans. J Allergy Clin Immunol. 1980 Nov; 66(5):358-65. PMID: 7002977.
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    111. Wasserman SI. The lung mast cell: its physiology and potential relevance to defense of the lung. Environ Health Perspect. 1980 Apr; 35:153-64. PMID: 6105956.
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    112. Petty HR, Ware BR, Wasserman SI. Alterations of the electrophoretic mobility distribution of rat mast cells after immunologic activation. Biophys J. 1980 Apr; 30(1):41-50. PMID: 7260269.
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    113. Metcalfe DD, Soter NA, Wasserman SI, Austen KF. Identification of sulfated mucopolysaccharides including heparin in the lesional skin of a patient with mastocytosis. J Invest Dermatol. 1980 Apr; 74(4):210-5. PMID: 6445388.
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    114. Wasserman SI, Ramsdell JW. The pharmacologic basis of asthma therapy. Compr Ther. 1980 Apr; 6(4):69-75. PMID: 6104556.
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    115. Soter NA, Wasserman SI, Austen KF, McFadden ER. Release of mast-cell mediators and alterations in lung function in patients with cholinergic urticaria. N Engl J Med. 1980 Mar 13; 302(11):604-8. PMID: 7351907.
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    116. Deal EC, Wasserman SI, Soter NA, Ingram RH, McFadden ER. Evaluation of role played by mediators of immediate hypersensitivity in exercise-induced asthma. J Clin Invest. 1980 Mar; 65(3):659-65. PMID: 7354133.
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    117. Metcalfe DD, Wasserman SI, Austen KF. Isolation and characterization of sulphated mucopolysaccharides from rat leukaemic (RBL-1) basophils. Biochem J. 1980 Feb 01; 185(2):367-72. PMID: 6446899.
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    118. Wasserman SI. The mast cell: its diversity of chemical mediators. Int J Dermatol. 1980 Jan-Feb; 19(1):7-17. PMID: 7358443.
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    119. Metcalfe DD, Lewis RA, Silbert JE, Rosenberg RD, Wasserman SI, Austen KF. Isolation and characterization of heparin from human lung. J Clin Invest. 1979 Dec; 64(6):1537-43. PMID: 500822.
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    120. Wasserman SI, Center DM. The relevance of neutrophil chemotactic factors to allergic disease. J Allergy Clin Immunol. 1979 Oct; 64(4):231-4. PMID: 479473.
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    121. Schwartz LB, Austen KF, Wasserman SI. Immunologic release of beta-hexosaminidase and beta-glucuronidase from purified rat serosal mast cells. J Immunol. 1979 Oct; 123(4):1445-50. PMID: 479592.
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    122. Soter NA, Wasserman SI. Urticaria/angioedema: a consideration of pathogenesis and clinical manifestations. Int J Dermatol. 1979 Sep; 18(7):517-32. PMID: 387620.
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    123. Soter NA, Austen KF, Wasserman SI. Oral disodium cromoglycate in the treatment of systemic mastocytosis. N Engl J Med. 1979 Aug 30; 301(9):465-9. PMID: 111124.
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    124. Drazen JM, Lewis RA, Wasserman SI, Orange RP, Austen KF. Differential effects of a partially purified preparation of slow-reacting substance of anaphylaxis on guinea pig tracheal spirals and parenchymal strips. J Clin Invest. 1979 Jan; 63(1):1-5. PMID: 762239.
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    125. Wasserman SI. Arylsulfatases and the inactivation of SRS-A. Monogr Allergy. 1979; 14:189-93. PMID: 503073.
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    126. Lynch SM, Austen KF, Wasserman SI. Release of arylsulfatase A but not B from rat mast cells by noncytolytic secretory stimuli. J Immunol. 1978 Oct; 121(4):1394-9. PMID: 81231.
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    127. Wasserman SI, Austen KF. Identification and characterization of arylsulfatase A and B of the rat basophil leukemia tumor. J Biol Chem. 1977 Oct 25; 252(20):7074-80. PMID: 20444.
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    128. Wasserman SI. The primary chemical mediators of immediate hypersensitivity: chemical and functional characterization and biochemical events in their generation and release. Scand J Respir Dis Suppl. 1977; 98:28-32. PMID: 72409.
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    129. Paterson NA, Wasserman SI, Said JW, Austen KF. Release of chemical mediators from partially purified human lung mast cells. J Immunol. 1976 Oct; 117(4):1356-62. PMID: 61999.
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    130. Soter NA, Wasserman SI, Austen KF. Cold urticaria: release into the circulation of histamine and eosinophil chemotactic factor of anaphylaxis during cold challenge. N Engl J Med. 1976 Mar 25; 294(13):687-90. PMID: 55969.
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    131. Wasserman SI, Goetzl EJ, Austen KF. Inactivation of slow reacting substance of anaphylaxis by human eosinophil arylsulfatase. J Immunol. 1975 Feb; 114(2 Pt 1):645-9. PMID: 235589.
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    132. Goetzl EJ, Wasserman SI, Austen F. Eosinophil polymorphonuclear leukocyte function in immediate hypersensitivity. Arch Pathol. 1975 Jan; 99(1):1-4. PMID: 234219.
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    133. Lewis RA, Goetzl EJ, Wasserman SI, Valone FH, Rubin RH, Austen KF. The release of four mediators of immediate hypersensitivity from human leukemic basophils. J Immunol. 1975 Jan; 114(1 Pt 1):87-92. PMID: 46247.
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    134. Wasserman SI, Goetzl EJ, Kaliner M, Austen KF. Modulation of the immunological release of the eosinophil chemotactic factor of anaphylaxis from human lung. Immunology. 1974 Apr; 26(4):677-84. PMID: 4137063.
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    135. Goetzl EJ, Wasserman SI, Gigli I, Austen KF. Enhancement of random migration and chemotactic response of human leukocytes by ascorbic acid. J Clin Invest. 1974 Mar; 53(3):813-8. PMID: 4273024.
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    136. Wasserman SI, Goetzl EJ, Ellman L, Austen KF. Tumor-associated eosinophilotactic factor. N Engl J Med. 1974 Feb 21; 290(8):420-4. PMID: 4811016.
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    137. Wasserman SI, Goetzl EJ, Austen KF. Preformed eosinophil chemotactic factor of anaphylaxis (ECF-A). J Immunol. 1974 Jan; 112(1):351-8. PMID: 4812176.
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    138. Goetzl EJ, Gigli I, Wasserman S, Austen KF. A neutrophil immobilizing factor derived from human leukocytes. II. Specificity of action on polymorphonuclear leukocyte mobility. J Immunol. 1973 Sep; 111(3):938-45. PMID: 4741302.
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    139. Kaliner M, Wasserman SI, Austen KF. Immunologic release of chemical mediators from human nasal polyps. N Engl J Med. 1973 Aug 09; 289(6):277-81. PMID: 4123994.
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