Donald Guiney

Title(s)Emeritus Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Intestinal Physiology in the Host Response to Enteric Salmonella Infections
    NIH R01AI077661Jan 1, 2009 - Dec 31, 2014
    Role: Principal Investigator
    Protection Against Inhalation Anthrax with Inactivated Spores
    NIH U01AI077989May 15, 2008 - Apr 30, 2013
    Role: Principal Investigator
    Salmonella-to-Eukaryotic Cell Multi-task Gene Delivery
    NIH R03AI064351May 1, 2005 - Apr 30, 2008
    Role: Principal Investigator
    INTERACTIONS OF HELICOBACTER WITH THE GASTRIC MUCOSA
    NIH R01DK053649Sep 30, 1997 - Sep 30, 2003
    Role: Principal Investigator
    HUMAN IMMUNE RESPONSE TO M TUBERCULOSIS LATENCY ANTIGENS
    NIH R01AI037005Sep 30, 1994 - Jul 31, 2000
    Role: Principal Investigator
    Plasmid-Mediated Virulence in Salmonella
    NIH R56AI032178Sep 1, 1993 - Sep 29, 2011
    Role: Principal Investigator
    Plasmid-Mediated Virulence in Salmonella
    NIH R01AI032178Sep 1, 1993 - Nov 30, 2009
    Role: Principal Investigator
    BLACK-PIGMENTED BACTEROIDES--DRUG RESISTANCE &VIRULENCE
    NIH R01DE007344Sep 1, 1985 - Jun 30, 1989
    Role: Principal Investigator
    MECHANISM OF PLASMID DNA TRANSFER IN BACTERIA
    NIH R01GM028924Sep 1, 1980 - Dec 31, 1994
    Role: Principal Investigator
    ANTIBIOTIC RESISTANCE OF BACTEROIDES
    NIH R01AI016463Feb 1, 1980 - Apr 30, 1996
    Role: Principal Investigator

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    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    1. Salmonella-induced Diarrhea Occurs in the Absence of IL-8 Receptor (CXCR2)-Dependent Neutrophilic Inflammation. J Infect Dis. 2015 Jul 01; 212(1):128-36. Marchelletta RR, Gareau MG, Okamoto S, Guiney DG, Barrett KE, Fierer J. PMID: 25538271; PMCID: PMC4542593.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    2. Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand. J Innate Immun. 2014; 6(3):315-24. Wu CC, Crain B, Yao S, Sabet M, Lao FS, Tawatao RI, Chan M, Smee DF, Julander JG, Cottam HB, Guiney DG, Corr M, Carson DA, Hayashi T. PMID: 24192551; PMCID: PMC3972367.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    3. Altered expression and localization of ion transporters contribute to diarrhea in mice with Salmonella-induced enteritis. Gastroenterology. 2013 Dec; 145(6):1358-1368.e1-4. Marchelletta RR, Gareau MG, McCole DF, Okamoto S, Roel E, Klinkenberg R, Guiney DG, Fierer J, Barrett KE. PMID: 24001788; PMCID: PMC3899031.
      View in: PubMed   Mentions: 31     Fields:    Translation:AnimalsCells
    4. Activated charcoal enhanced the antigen-expression and dendritic cell maturation of the vaccine using Listeria-platform. Kobe J Med Sci. 2012 Sep 13; 58(3):E63-71. Wanram S, Guiney D, Panomket P, Jearanaikoon P. PMID: 23143471.
      View in: PubMed   Mentions:    Fields:    Translation:AnimalsCells
    5. Microbiological analysis of nontyphoidal Salmonella strains causing distinct syndromes of bacteremia or enteritis in HIV/AIDS patients in San Diego, California. J Clin Microbiol. 2012 Nov; 50(11):3598-603. Preziosi MJ, Kandel SM, Guiney DG, Browne SH. PMID: 22933605; PMCID: PMC3486235.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    6. Diarrhea and colitis in mice require the Salmonella pathogenicity island 2-encoded secretion function but not SifA or Spv effectors. Infect Immun. 2012 Oct; 80(10):3360-70. Fierer J, Okamoto S, Banerjee A, Guiney DG. PMID: 22778101; PMCID: PMC3457546.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    7. Effects of myeloid differentiation primary response gene 88 (MyD88) activation on Helicobacter infection in vivo and induction of a Th17 response. Helicobacter. 2011 Oct; 16(5):398-404. Obonyo M, Rickman B, Guiney DG. PMID: 21923686; PMCID: PMC3535435.
      View in: PubMed   Mentions: 13     Fields:    Translation:AnimalsCells
    8. Improving reverse vaccinology with a machine learning approach. Vaccine. 2011 Oct 19; 29(45):8156-64. Bowman BN, McAdam PR, Vivona S, Zhang JX, Luong T, Belew RK, Sahota H, Guiney D, Valafar F, Fierer J, Woelk CH. PMID: 21864619.
      View in: PubMed   Mentions: 26     Fields:    Translation:Humans
    9. The Role of the spv Genes in Salmonella Pathogenesis. Front Microbiol. 2011; 2:129. Guiney DG, Fierer J. PMID: 21716657; PMCID: PMC3117207.
      View in: PubMed   Mentions: 104  
    10. Penetration and activation of brain endothelium by Salmonella enterica serovar Typhimurium. J Infect Dis. 2011 Feb 01; 203(3):401-5. van Sorge NM, Zialcita PA, Browne SH, Quach D, Guiney DG, Doran KS. PMID: 21186258; PMCID: PMC3071103.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    11. Mucosal adjuvant activity of cholera toxin requires Th17 cells and protects against inhalation anthrax. Proc Natl Acad Sci U S A. 2010 Jun 08; 107(23):10638-43. Datta SK, Sabet M, Nguyen KP, Valdez PA, Gonzalez-Navajas JM, Islam S, Mihajlov I, Fierer J, Insel PA, Webster NJ, Guiney DG, Raz E. PMID: 20479237; PMCID: PMC2890829.
      View in: PubMed   Mentions: 90     Fields:    Translation:AnimalsCells
    12. NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH. Chem Biol Drug Des. 2010 Jul; 76(1):10-6. Leone M, Barile E, Vazquez J, Mei A, Guiney D, Dahl R, Pellecchia M. PMID: 20456369; PMCID: PMC2905849.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    13. Small molecule DnaK modulators targeting the beta-domain. Chem Biol Drug Des. 2009 Oct; 74(4):349-57. Cellitti J, Zhang Z, Wang S, Wu B, Yuan H, Hasegawa P, Guiney DG, Pellecchia M. PMID: 19694756; PMCID: PMC2858402.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    14. ClpX contributes to innate defense peptide resistance and virulence phenotypes of Bacillus anthracis. J Innate Immun. 2009; 1(5):494-506. McGillivray SM, Ebrahimi CM, Fisher N, Sabet M, Zhang DX, Chen Y, Haste NM, Aroian RV, Gallo RL, Guiney DG, Friedlander AM, Koehler TM, Nizet V. PMID: 20375606; PMCID: PMC2920483.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    15. Structure-activity relationship studies of a novel series of anthrax lethal factor inhibitors. Bioorg Med Chem. 2009 May 01; 17(9):3352-68. Johnson SL, Chen LH, Barile E, Emdadi A, Sabet M, Yuan H, Wei J, Guiney D, Pellecchia M. PMID: 19359184; PMCID: PMC2730741.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    16. Myeloid differentiation primary response gene 88 is required for the resolution of otitis media. J Infect Dis. 2008 Dec 15; 198(12):1862-9. Hernandez M, Leichtle A, Pak K, Ebmeyer J, Euteneuer S, Obonyo M, Guiney DG, Webster NJ, Broide DH, Ryan AF, Wasserman SI. PMID: 18986247; PMCID: PMC3584630.
      View in: PubMed   Mentions: 46     Fields:    Translation:AnimalsCells
    17. Anthrax toxins inhibit neutrophil signaling pathways in brain endothelium and contribute to the pathogenesis of meningitis. PLoS One. 2008 Aug 13; 3(8):e2964. van Sorge NM, Ebrahimi CM, McGillivray SM, Quach D, Sabet M, Guiney DG, Doran KS. PMID: 18698416; PMCID: PMC2493037.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    18. In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cell Immunol. 2008 Feb; 251(2):78-85. Wu CC, Sabet M, Hayashi T, Tawatao R, Fierer J, Carson DA, Guiney DG, Corr M. PMID: 18495099; PMCID: PMC4012540.
      View in: PubMed   Mentions: 10     Fields:    Translation:AnimalsCellsPHPublic Health
    19. Retraction. Induction of a homeostatic circuit in lung tissue by microbial compounds. Immunity. 2008 May; 28(5):724. Takabayshi K, Corr M, Hayashi T, Redecke V, Beck L, Guiney D, Sheppard D, Raz E. PMID: 18504811.
      View in: PubMed   Mentions:    Fields:    
    20. Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses. J Immunol. 2008 Apr 01; 180(7):5045-56. Le Negrate G, Faustin B, Welsh K, Loeffler M, Krajewska M, Hasegawa P, Mukherjee S, Orth K, Krajewski S, Godzik A, Guiney DG, Reed JC. PMID: 18354230.
      View in: PubMed   Mentions: 76     Fields:    Translation:HumansAnimalsCells
    21. A model of Salmonella colitis with features of diarrhea in SLC11A1 wild-type mice. PLoS One. 2008 Feb 13; 3(2):e1603. Woo H, Okamoto S, Guiney D, Gunn JS, Fierer J. PMID: 18270590; PMCID: PMC2225501.
      View in: PubMed   Mentions: 22     Fields:    Translation:AnimalsCells
    22. Identification of Salmonella SPI-2 secretion system components required for SpvB-mediated cytotoxicity in macrophages and virulence in mice. FEMS Immunol Med Microbiol. 2008 Mar; 52(2):194-201. Browne SH, Hasegawa P, Okamoto S, Fierer J, Guiney DG. PMID: 18248436.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    23. Rhodanine derivatives as selective protease inhibitors against bacterial toxins. Chem Biol Drug Des. 2008 Feb; 71(2):131-9. Johnson SL, Chen LH, Harbach R, Sabet M, Savinov A, Cotton NJ, Strongin A, Guiney D, Pellecchia M. PMID: 18221310.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansCells
    24. Complement C3d conjugation to anthrax protective antigen promotes a rapid, sustained, and protective antibody response. PLoS One. 2007 Oct 17; 2(10):e1044. Kolla RV, Chintalapati S, Sabet M, Santelli E, Liddington RC, David M, Fierer J, Guiney D, Rickert RC. PMID: 17940608; PMCID: PMC2001179.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    25. Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens. J Biol Chem. 2007 Jul 20; 282(29):20847-53. Shiryaev SA, Remacle AG, Ratnikov BI, Nelson NA, Savinov AY, Wei G, Bottini M, Rega MF, Parent A, Desjardins R, Fugere M, Day R, Sabet M, Pellecchia M, Liddington RC, Smith JW, Mustelin T, Guiney DG, Lebl M, Strongin AY. PMID: 17537721.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    26. Deficiencies of myeloid differentiation factor 88, Toll-like receptor 2 (TLR2), or TLR4 produce specific defects in macrophage cytokine secretion induced by Helicobacter pylori. Infect Immun. 2007 May; 75(5):2408-14. Obonyo M, Sabet M, Cole SP, Ebmeyer J, Uematsu S, Akira S, Guiney DG. PMID: 17353291; PMCID: PMC1865764.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    27. Modulation of cytokine production and enhancement of cell viability by TLR7 and TLR9 ligands during anthrax infection of macrophages. FEMS Immunol Med Microbiol. 2006 Aug; 47(3):369-79. Sabet M, Cottam HB, Guiney DG. PMID: 16872373.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    28. Evidence for interleukin-1-independent stimulation of interleukin-12 and down-regulation by interleukin-10 in Helicobacter pylori-infected murine dendritic cells deficient in the interleukin-1 receptor. FEMS Immunol Med Microbiol. 2006 Aug; 47(3):414-9. Obonyo M, Cole SP, Datta SK, Guiney DG. PMID: 16872378.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    29. Vaccination with irradiated Listeria induces protective T cell immunity. Immunity. 2006 Jul; 25(1):143-52. Datta SK, Okamoto S, Hayashi T, Shin SS, Mihajlov I, Fermin A, Guiney DG, Fierer J, Raz E. PMID: 16860763.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCellsPHPublic Health
    30. Induction of a homeostatic circuit in lung tissue by microbial compounds. Immunity. 2006 Apr; 24(4):475-87. Takabayshi K, Corr M, Hayashi T, Redecke V, Beck L, Guiney D, Sheppard D, Raz E. PMID: 16618605.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    31. CpG oligonucleotides partially inhibit growth of Mycobacterium tuberculosis, but not Salmonella or Listeria, in human monocyte-derived macrophages. FEMS Immunol Med Microbiol. 2005 Aug 01; 45(2):303-10. Wang JP, Hayashi T, Datta SK, Kornbluth RS, Raz E, Guiney DG. PMID: 16002269.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    32. Characterization of Salmonella-induced cell death in human macrophage-like THP-1 cells. Infect Immun. 2005 May; 73(5):2835-40. Valle E, Guiney DG. PMID: 15845488; PMCID: PMC1087321.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansCells
    33. Targeting of the actin cytoskeleton during infection by Salmonella strains. Clin Immunol. 2005 Mar; 114(3):248-55. Guiney DG, Lesnick M. PMID: 15721835.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansAnimalsCells
    34. The role of host cell death in Salmonella infections. Curr Top Microbiol Immunol. 2005; 289:131-50. Guiney DG. PMID: 15791954.
      View in: PubMed   Mentions: 47     Fields:    Translation:HumansAnimalsCells
    35. Induction and antimicrobial activity of platelet basic protein derivatives in human monocytes. J Leukoc Biol. 2004 Nov; 76(5):1010-8. Schaffner A, King CC, Schaer D, Guiney DG. PMID: 15316029.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCells
    36. Characterization of monospecies biofilm formation by Helicobacter pylori. J Bacteriol. 2004 May; 186(10):3124-32. Cole SP, Harwood J, Lee R, She R, Guiney DG. PMID: 15126474; PMCID: PMC400600.
      View in: PubMed   Mentions: 91     Fields:    Translation:Cells
    37. The protein kinase PKR is required for macrophage apoptosis after activation of Toll-like receptor 4. Nature. 2004 Mar 18; 428(6980):341-5. Hsu LC, Park JM, Zhang K, Luo JL, Maeda S, Kaufman RJ, Eckmann L, Guiney DG, Karin M. PMID: 15029200.
      View in: PubMed   Mentions: 151     Fields:    Translation:AnimalsCells
    38. Gene expression profiling detects patterns of human macrophage responses following Mycobacterium tuberculosis infection. FEMS Immunol Med Microbiol. 2003 Nov 28; 39(2):163-72. Wang JP, Rought SE, Corbeil J, Guiney DG. PMID: 14625100.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCells
    39. Helicobacter pylori preferentially induces interleukin 12 (IL-12) rather than IL-6 or IL-10 in human dendritic cells. Infect Immun. 2003 Jul; 71(7):4163-6. Guiney DG, Hasegawa P, Cole SP. PMID: 12819109; PMCID: PMC161996.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
    40. Interactions between inducible nitric oxide and other inflammatory mediators during Helicobacter pylori infection. Helicobacter. 2003; 8(5):495-502. Obonyo M, Guiney DG, Fierer J, Cole SP. PMID: 14535996.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    41. Genetic requirements for salmonella-induced cytopathology in human monocyte-derived macrophages. Infect Immun. 2002 Dec; 70(12):7126-35. Browne SH, Lesnick ML, Guiney DG. PMID: 12438395; PMCID: PMC133012.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    42. Genes in the Salmonella pathogenicity island 2 and the Salmonella virulence plasmid are essential for Salmonella-induced apoptosis in intestinal epithelial cells. Cell Microbiol. 2002 Nov; 4(11):771-81. Paesold G, Guiney DG, Eckmann L, Kagnoff MF. PMID: 12427099.
      View in: PubMed   Mentions: 40     Fields:    Translation:HumansCells
    43. Salmonella enterica serovar Typhimurium periplasmic superoxide dismutases SodCI and SodCII are required for protection against the phagocyte oxidative burst. Infect Immun. 2002 Sep; 70(9):5312-5. Sly LM, Guiney DG, Reiner NE. PMID: 12183590; PMCID: PMC128279.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    44. Characterization of the spv locus in Salmonella enterica serovar Arizona. Infect Immun. 2002 Jun; 70(6):3290-4. Libby SJ, Lesnick M, Hasegawa P, Kurth M, Belcher C, Fierer J, Guiney DG. PMID: 12011028; PMCID: PMC127997.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    45. Role of gamma interferon in Helicobacter pylori induction of inflammatory mediators during murine infection. Infect Immun. 2002 Jun; 70(6):3295-9. Obonyo M, Guiney DG, Harwood J, Fierer J, Cole SP. PMID: 12011029; PMCID: PMC127973.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    46. Diverse virulence traits underlying different clinical outcomes of Salmonella infection. J Clin Invest. 2001 Apr; 107(7):775-80. Fierer J, Guiney DG. PMID: 11285291; PMCID: PMC199580.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimalsCells
    47. The Salmonella spvB virulence gene encodes an enzyme that ADP-ribosylates actin and destabilizes the cytoskeleton of eukaryotic cells. Mol Microbiol. 2001 Mar; 39(6):1464-70. Lesnick ML, Reiner NE, Fierer J, Guiney DG. PMID: 11260464.
      View in: PubMed   Mentions: 71     Fields:    Translation:AnimalsCells
    48. The best defense is a good offense--Salmonella deploys an ADP-ribosylating toxin. Trends Microbiol. 2001 Jan; 9(1):2-4; discussion 4-5. Lesnick ML, Guiney DG. PMID: 11166220.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    49. Effect of nitric oxide on Helicobacter pylori morphology. J Infect Dis. 1999 Nov; 180(5):1713-7. Cole SP, Kharitonov VF, Guiney DG. PMID: 10515839.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    50. SlyA, a transcriptional regulator of Salmonella typhimurium, is required for resistance to oxidative stress and is expressed in the intracellular environment of macrophages. Infect Immun. 1997 Sep; 65(9):3725-30. Buchmeier N, Bossie S, Chen CY, Fang FC, Guiney DG, Libby SJ. PMID: 9284144; PMCID: PMC175531.
      View in: PubMed   Mentions: 75     Fields:    Translation:AnimalsCells
    51. Mutational characterization of promoter regions recognized by the Salmonella dublin virulence plasmid regulatory protein SpvR. J Bacteriol. 1997 Sep; 179(17):5398-406. Grob P, Kahn D, Guiney DG. PMID: 9286993; PMCID: PMC179409.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    52. The spv genes on the Salmonella dublin virulence plasmid are required for severe enteritis and systemic infection in the natural host. Infect Immun. 1997 May; 65(5):1786-92. Libby SJ, Adams LG, Ficht TA, Allen C, Whitford HA, Buchmeier NA, Bossie S, Guiney DG. PMID: 9125562; PMCID: PMC175217.
      View in: PubMed   Mentions: 51     Fields:    Translation:AnimalsCells
    53. Regulation of bacterial virulence gene expression by the host environment. J Clin Invest. 1997 Feb 15; 99(4):565-9. Guiney DG. PMID: 9045855; PMCID: PMC507835.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    54. Coccoid and spiral Helicobacter pylori differ in their abilities to adhere to gastric epithelial cells and induce interleukin-8 secretion. Infect Immun. 1997 Feb; 65(2):843-6. Cole SP, Cirillo D, Kagnoff MF, Guiney DG, Eckmann L. PMID: 9009355; PMCID: PMC176138.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    55. Expression of Salmonella typhimurium rpoS and rpoS-dependent genes in the intracellular environment of eukaryotic cells. Infect Immun. 1996 Nov; 64(11):4739-43. Chen CY, Eckmann L, Libby SJ, Fang FC, Okamoto S, Kagnoff MF, Fierer J, Guiney DG. PMID: 8890234; PMCID: PMC174440.
      View in: PubMed   Mentions: 35     Fields:    Translation:HumansAnimalsCells
    56. In vitro binding of the Salmonella dublin virulence plasmid regulatory protein SpvR to the promoter regions of spvA and spvR. J Bacteriol. 1996 Apr; 178(7):1813-20. Grob P, Guiney DG. PMID: 8606153; PMCID: PMC177874.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    57. Site-specific mutations in the traI relaxase and upstream region of plasmid RP4. Plasmid. 1995 Nov; 34(3):236-9. Cole SP, Guiney DG. PMID: 8825378.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    58. Biology and clinical significance of virulence plasmids in Salmonella serovars. Clin Infect Dis. 1995 Oct; 21 Suppl 2:S146-51. Guiney DG, Fang FC, Krause M, Libby S, Buchmeier NA, Fierer J. PMID: 8845442.
      View in: PubMed   Mentions: 37     Fields:    Translation:HumansAnimalsCells
    59. Central regulatory role for the RpoS sigma factor in expression of Salmonella dublin plasmid virulence genes. J Bacteriol. 1995 Sep; 177(18):5303-9. Chen CY, Buchmeier NA, Libby S, Fang FC, Krause M, Guiney DG. PMID: 7665519; PMCID: PMC177323.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCells
    60. Growth-phase regulation of plasmid virulence genes in Salmonella. Trends Microbiol. 1995 Jul; 3(7):275-9. Guiney DG, Libby S, Fang FC, Krause M, Fierer J. PMID: 7551642.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    61. Plasmid-mediated virulence genes in non-typhoid Salmonella serovars. FEMS Microbiol Lett. 1994 Nov 15; 124(1):1-9. Guiney DG, Fang FC, Krause M, Libby S. PMID: 8001760.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    62. Specificity of the complement resistance and cell association phenotypes encoded by the outer membrane protein genes rck from Salmonella typhimurium and ail from Yersinia enterocolitica. Infect Immun. 1994 Nov; 62(11):5183-6. Heffernan EJ, Wu L, Louie J, Okamoto S, Fierer J, Guiney DG. PMID: 7927803; PMCID: PMC303245.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansAnimalsCells
    63. Expression of the Salmonella virulence plasmid gene spvB in cultured macrophages and nonphagocytic cells. Infect Immun. 1993 Dec; 61(12):5231-6. Fierer J, Eckmann L, Fang F, Pfeifer C, Finlay BB, Guiney D. PMID: 8225598; PMCID: PMC281306.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    64. Value of molecular epidemiologic analysis in a nosocomial methicillin-resistant Staphylococcus aureus outbreak. JAMA. 1993 Sep 15; 270(11):1323-8. Fang FC, McClelland M, Guiney DG, Jackson MM, Hartstein AI, Morthland VH, Davis CE, McPherson DC, Welsh J. PMID: 8103118.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCellsPHPublic Health
    65. Processes at the nick region link conjugation, T-DNA transfer and rolling circle replication. Mol Microbiol. 1993 Sep; 9(6):1123-30. Waters VL, Guiney DG. PMID: 7934927.
      View in: PubMed   Mentions: 30     Fields:    Translation:Cells
    66. Molecular analysis of a gene encoding a serum-resistance-associated 76 kDa surface antigen of Haemophilus somnus. J Gen Microbiol. 1993 Sep; 139(9):2135-43. Cole SP, Guiney DG, Corbeil LB. PMID: 8245839.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    67. Site-directed mutations in the relaxase operon of RP4. J Bacteriol. 1993 Aug; 175(15):4911-6. Cole SP, Lanka E, Guiney DG. PMID: 8335645; PMCID: PMC204946.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    68. The alternative sigma factor katF (rpoS) regulates Salmonella virulence. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11978-82. Fang FC, Libby SJ, Buchmeier NA, Loewen PC, Switala J, Harwood J, Guiney DG. PMID: 1465428; PMCID: PMC50681.
      View in: PubMed   Mentions: 233     Fields:    Translation:AnimalsCells
    69. Characterization of translation termination mutations in the spv operon of the Salmonella virulence plasmid pSDL2. J Bacteriol. 1992 Oct; 174(20):6418-23. Roudier C, Fierer J, Guiney DG. PMID: 1400193; PMCID: PMC207594.
      View in: PubMed   Mentions: 22     Fields:    Translation:Cells
    70. Mutational analysis of essential IncP alpha plasmid transfer genes traF and traG and involvement of traF in phage sensitivity. J Bacteriol. 1992 Oct; 174(20):6666-73. Waters VL, Strack B, Pansegrau W, Lanka E, Guiney DG. PMID: 1400217; PMCID: PMC207648.
      View in: PubMed   Mentions: 31     Fields:    Translation:Cells
    71. Salmonella typhimurium bacteremia: association with the virulence plasmid. J Infect Dis. 1992 Sep; 166(3):639-42. Fierer J, Krause M, Tauxe R, Guiney D. PMID: 1500749.
      View in: PubMed   Mentions: 26     Fields:    Translation:HumansCells
    72. Mechanism of resistance to complement-mediated killing of bacteria encoded by the Salmonella typhimurium virulence plasmid gene rck. J Clin Invest. 1992 Sep; 90(3):953-64. Heffernan EJ, Reed S, Hackett J, Fierer J, Roudier C, Guiney D. PMID: 1522243; PMCID: PMC329951.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    73. Transfer of conjugal elements in oral black-pigmented Bacteroides (Prevotella) spp. involves DNA rearrangements. J Bacteriol. 1992 Jul; 174(14):4853-5. Guiney DG, Hasegawa P. PMID: 1624474; PMCID: PMC206288.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    74. Two linked genes for outer membrane proteins are absent in four non-disease strains of Haemophilus somnus. Mol Microbiol. 1992 Jul; 6(14):1895-902. Cole SP, Guiney DG, Corbeil LB. PMID: 1508038.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    75. Regulation of plasmid virulence gene expression in Salmonella dublin involves an unusual operon structure. J Bacteriol. 1992 Jul; 174(13):4482-9. Krause M, Fang FC, Guiney DG. PMID: 1378053; PMCID: PMC206235.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    76. The Salmonella typhimurium virulence plasmid complement resistance gene rck is homologous to a family of virulence-related outer membrane protein genes, including pagC and ail. J Bacteriol. 1992 Jan; 174(1):84-91. Heffernan EJ, Harwood J, Fierer J, Guiney D. PMID: 1729227; PMCID: PMC205680.
      View in: PubMed   Mentions: 66     Fields:    Translation:Cells
    77. Growth regulation of a Salmonella plasmid gene essential for virulence. J Bacteriol. 1991 Nov; 173(21):6783-9. Fang FC, Krause M, Roudier C, Fierer J, Guiney DG. PMID: 1938884; PMCID: PMC209028.
      View in: PubMed   Mentions: 39     Fields:    Translation:Cells
    78. Identification of a multimer resolution system involved in stabilization of the Salmonella dublin virulence plasmid pSDL2. J Bacteriol. 1991 Sep; 173(18):5754-62. Krause M, Guiney DG. PMID: 1653217; PMCID: PMC208307.
      View in: PubMed   Mentions: 17     Fields:    Translation:Cells
    79. A site-specific DNA inversion in Bacteroides plasmid pBF4 is influenced by the presence of the conjugal tetracycline resistance element. J Bacteriol. 1991 Aug; 173(16):5239-43. Matthews BG, Roudier C, Guiney DG. PMID: 1650348; PMCID: PMC208220.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    80. Genetic analysis of homology between the virulence plasmids of Salmonella dublin and Yersinia pseudotuberculosis. Infect Immun. 1991 May; 59(5):1860-3. Krause M, Harwood J, Fierer J, Guiney D. PMID: 1840573; PMCID: PMC257928.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    81. Sequence identity in the nick regions of IncP plasmid transfer origins and T-DNA borders of Agrobacterium Ti plasmids. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1456-60. Waters VL, Hirata KH, Pansegrau W, Lanka E, Guiney DG. PMID: 1996345; PMCID: PMC51037.
      View in: PubMed   Mentions: 43     Fields:    Translation:Cells
    82. Molecular analysis of the virulence locus of the Salmonella dublin plasmid pSDL2. Mol Microbiol. 1991 Feb; 5(2):307-16. Krause M, Roudier C, Fierer J, Harwood J, Guiney D. PMID: 2041471.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    83. Isolation and expression of the gene for a major surface protein of Giardia lamblia. Proc Natl Acad Sci U S A. 1990 Jun; 87(12):4463-7. Gillin FD, Hagblom P, Harwood J, Aley SB, Reiner DS, McCaffery M, So M, Guiney DG. PMID: 2352929; PMCID: PMC54135.
      View in: PubMed   Mentions: 43     Fields:    Translation:AnimalsCells
    84. Homologous DNA sequences on the virulence plasmids of pathogenic Yersinia and Salmonella dublin lane. Mol Microbiol. 1990 Jun; 4(6):905-11. Krause M, Fierer J, Guiney D. PMID: 2215215.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    85. Correlation between the presence of sequences homologous to the vir region of Salmonella dublin plasmid pSDL2 and the virulence of twenty-two Salmonella serotypes in mice. Infect Immun. 1990 May; 58(5):1180-5. Roudier C, Krause M, Fierer J, Guiney DG. PMID: 2323813; PMCID: PMC258607.
      View in: PubMed   Mentions: 28     Fields:    Translation:AnimalsCells
    86. Initiation of DNA synthesis in the transfer origin region of RK2 by the plasmid-encoded primase: detection using defective M13 phage. Plasmid. 1990 Jan; 23(1):80-4. Yakobson E, Deiss C, Hirata K, Guiney DG. PMID: 2349284.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    87. Detection of conjugal transfer systems in oral, black-pigmented Bacteroides spp. J Bacteriol. 1990 Jan; 172(1):495-7. Guiney DG, Bouic K. PMID: 2294095; PMCID: PMC208461.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    88. Genetic transfer systems in Bacteroides: cloning and mapping of the transferable tetracycline-resistance locus. Mol Microbiol. 1989 Nov; 3(11):1617-23. Guiney DG, Hasegawa P, Bouic K, Matthews B. PMID: 2615657.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    89. myc-related proteins and DNA sequences in Trypanosoma brucei. Microb Pathog. 1989 Jul; 7(1):45-53. Davis CE, Colmerauer ME, Kim CH, Matthews B, Guiney DG. PMID: 2554090.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    90. Mutagenesis of the Tra1 core region of RK2 by using Tn5: identification of plasmid-specific transfer genes. J Bacteriol. 1989 Jul; 171(7):4100-3. Guiney DG, Deiss C, Simnad V, Yee L, Pansegrau W, Lanka E. PMID: 2544570; PMCID: PMC210173.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    91. Location of the relaxation complex nick site within the minimal origin of transfer region of RK2. Plasmid. 1988 Nov; 20(3):259-65. Guiney DG, Deiss C, Simnad V. PMID: 3072579.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    92. Cloning and expression of genes encoding Haemophilus somnus antigens. Infect Immun. 1988 Oct; 56(10):2736-42. Corbeil LB, Chikami G, Yarnall M, Smith J, Guiney DG. PMID: 2843469; PMCID: PMC259637.
      View in: PubMed   Mentions: 8     Fields:    Translation:Cells
    93. Production of a heat stable enterotoxin by Plesiomonas shigelloides. Microb Pathog. 1988 Sep; 5(3):207-13. Matthews BG, Douglas H, Guiney DG. PMID: 3216779.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    94. Active immunization with LD842, a plasmid-cured strain of Salmonella dublin, protects mice against group D and group B Salmonella infection. J Infect Dis. 1988 Aug; 158(2):460-3. Fierer J, Chikami G, Hatlen L, Heffernan EJ, Guiney D. PMID: 3403995.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCellsPHPublic Health
    95. Construction of shuttle cloning vectors for Bacteroides fragilis and use in assaying foreign tetracycline resistance gene expression. Plasmid. 1988 Jul; 20(1):17-22. Guiney DG, Bouic K, Hasegawa P, Matthews B. PMID: 3071818.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    96. Physical and genetic mapping of the Salmonella dublin virulence plasmid pSDL2. Relationship to plasmids from other Salmonella strains. J Clin Invest. 1988 May; 81(5):1341-7. Beninger PR, Chikami G, Tanabe K, Roudier C, Fierer J, Guiney DG. PMID: 2835396; PMCID: PMC442562.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    97. Conjugal transfer of bacterial chromosomes mediated by the RK2 plasmid transfer origin cloned into transposon Tn5. J Bacteriol. 1984 Oct; 160(1):451-3. Yakobson EA, Guiney DG. PMID: 6090433; PMCID: PMC214743.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    98. Homology between clindamycin resistance plasmids in Bacteroides. Plasmid. 1984 May; 11(3):268-71. Guiney DG, Hasegawa P, Davis CE. PMID: 6087395.
      View in: PubMed   Mentions: 18     Fields:    Translation:Cells
    99. Expression in Escherichia coli of cryptic tetracycline resistance genes from bacteroides R plasmids. Plasmid. 1984 May; 11(3):248-52. Guiney DG, Hasegawa P, Davis CE. PMID: 6379711.
      View in: PubMed   Mentions: 47     Fields:    Translation:Cells
    100. Promiscuous transfer of drug resistance in gram-negative bacteria. J Infect Dis. 1984 Mar; 149(3):320-9. Guiney DG. PMID: 6143782.
      View in: PubMed   Mentions: 16     Fields:    Translation:Cells
    101. Mechanism of action of metronidazole on Bacteroides fragilis. J Infect Dis. 1983 Dec; 148(6):1083-9. Sigeti JS, Guiney DG, Davis CE. PMID: 6197496.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    102. Genetic analysis of clindamycin resistance in Bacteroides species. J Infect Dis. 1983 Mar; 147(3):551-8. Guiney DG, Hasegawa P, Stalker D, Davis CE. PMID: 6833799.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    103. The role of lipopolysaccharide structure in the recipient cell during plasmid-mediated bacterial conjugation. Plasmid. 1983 Mar; 9(2):222-6. Duke J, Guiney DG. PMID: 6856692.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    104. Transfer of the gonococcal penicillinase plasmid: mobilization in Escherichia coli by IncP plasmids and isolation as a DNA-protein relaxation complex. J Bacteriol. 1982 Apr; 150(1):298-302. Guiney DG, Ito JI. PMID: 6801022; PMCID: PMC220113.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    105. Identification of a conjugative R plasmid in Bacteroides ochraceus capable of transfer to Escherichia coli. Nature. 1978 Jul 13; 274(5667):181-2. Guiney DG, Davis CE. PMID: 351428.
      View in: PubMed   Mentions: 15     Fields:    Translation:Cells
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