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Seema Aceves

Title(s)Professor Of Clinical, Pediatrics
SchoolHealth Sciences
Phone858-534-2983
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    Collapse Biography 
    Collapse Education and Training
    UC San DiegoMD, PhDMedical Scientist Training Program

    Collapse Overview 
    Collapse Overview
    Dr. Aceves completed both her medical degree and her PhD through the Medical Scientist Training Program at UC San Diego. She also completed her pediatric internship, residency and a fellowship in allergy and immunology at UC San Diego.

    Dr. Aceves was named a Physician of Exceptional Excellence in the 2012 "San Diego's Top Doctors" survey from the San Diego County Medical Society and San Diego Magazine.

    She was elected to the American Society for Clinical Investigation in 2013.

    Collapse Research 
    Collapse Research Activities and Funding
    LIGHT/TNFSF14 in allergic esophagitis remodeling
    NIH/NIDDK R01DK114457Apr 1, 2018 - Feb 28, 2022
    Role: Co-Principal Investigator
    Mentoring Patient Oriented Research in Allergic Eosinophilic Gastrointestinal Disorders
    NIH/NIAID K24AI135034Dec 12, 2017 - Nov 30, 2022
    Role: Principal Investigator
    Consortium of Eosinophilic Gastrointestinal Disease Researchers
    NIH U54AI117804Aug 15, 2014 - Jul 31, 2019
    Role: Co-Investigator
    Contribution of rigid matrix to allergic eosinophilic esophagitis pathogenesis
    NIH/NIAID R01AI092135Jul 1, 2011 - Jun 30, 2021
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Collins C, Palmquist J, Proudfoot JA, Qian A, Wangberg H, Khosh-Hemmat E, Dohil R, Aceves SS. Evaluation of Long-term Course in Children with Eosinophilic Esophagitis Reveals Distinct Histologic Patterns and Clinical Characteristics. J Allergy Clin Immunol. 2019 Jun 27. PMID: 31255641.
      View in: PubMed
    2. Aceves SS. Local Antigen Deposition in Eosinophilic Esophagitis: Implications for Immune Activation. Gastroenterology. 2019 Jul; 157(1):17-20. PMID: 31150607.
      View in: PubMed
    3. Kurten RC, Rawson R, Shoda T, Duong LD, Adejumobi D, Levy R, Newbury RO, Rothenberg ME, Akuthota P, Wright BL, Dohil R, Jones SM, Aceves SS. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Sci Rep. 2019 Apr 17; 9(1):6206. PMID: 30996235.
      View in: PubMed
    4. Hassan M, Aceves S, Dohil R, Gharibans A, Newbury R, Proudfoot J, Mousa H. Esophageal Compliance Quantifies Epithelial Remodeling in Pediatric Patients With Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 Apr; 68(4):559-565. PMID: 30418408.
      View in: PubMed
    5. Muir AB, Jensen ET, Wechsler JB, Menard-Katcher P, Falk GW, Aceves SS, Furuta GT, Dellon ES, Rothenberg ME, Spergel JM. Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. J Allergy Clin Immunol Pract. 2019 Mar 25. PMID: 30922989.
      View in: PubMed
    6. Doshi A, Khamishon R, Rawson R, Duong L, Dohil L, Myers SJ, Bell B, Dohil R, Newbury RO, Barrett KE, Kurten RC, Aceves SS. Interleukin 9 Alters Epithelial Barrier and E-cadherin in Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 Feb; 68(2):225-231. PMID: 30211842.
      View in: PubMed
    7. Schoepfer AM, Hirano I, Coslovsky M, Roumet MC, Zwahlen M, Kuehni CE, Hafner D, Alexander JA, Dellon ES, Gonsalves N, Leung J, Bussmann C, Collins MH, Newbury RO, Smyrk TC, Woosley JT, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Falk GW, Meltzer BA, Comer GM, Straumann A, Safroneeva E. Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults with Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2018 Nov 23. PMID: 30476587.
      View in: PubMed
    8. Gupta SK, Falk GW, Aceves SS, Chehade M, Collins MH, Dellon ES, Gonsalves N, Hirano I, Mukkuda VA, Peterson KA, Spergel J, Yang GY, Furuta GT, Rothenberg ME. Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration. Gastroenterology. 2019 03; 156(4):838-842. PMID: 30452923.
      View in: PubMed
    9. Dellon ES, Liacouras CA, Molina-Infante J, Furuta GT, Spergel JM, Zevit N, Spechler SJ, Attwood SE, Straumann A, Aceves SS, Alexander JA, Atkins D, Arva NC, Blanchard C, Bonis PA, Book WM, Capocelli KE, Chehade M, Cheng E, Collins MH, Davis CM, Dias JA, Di Lorenzo C, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox A, Gonsalves NP, Gupta SK, Katzka DA, Kinoshita Y, Menard-Katcher C, Kodroff E, Metz DC, Miehlke S, Muir AB, Mukkada VA, Murch S, Nurko S, Ohtsuka Y, Orel R, Papadopoulou A, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Rothenberg ME, Schoepfer A, Scott MM, Shah N, Sheikh J, Souza RF, Strobel MJ, Talley NJ, Vaezi MF, Vandenplas Y, Vieira MC, Walker MM, Wechsler JB, Wershil BK, Wen T, Yang GY, Hirano I, Bredenoord AJ. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018 10; 155(4):1022-1033.e10. PMID: 30009819.
      View in: PubMed
    10. Spergel J, Aceves SS. Allergic components of eosinophilic esophagitis. J Allergy Clin Immunol. 2018 Jul; 142(1):1-8. PMID: 29980277.
      View in: PubMed
    11. Ma C, van Rhijn BD, Jairath V, Nguyen TM, Parker CE, Aceves SS, Furuta GT, Gupta SK, Katzka DA, Safroneeva E, Schoepfer AM, Straumann A, Spergel JM, Pai RK, Feagan BG, Hirano I, Dellon ES, Bredenoord AJ. Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 Nov; 16(11):1714-1729.e3. PMID: 29908360.
      View in: PubMed
    12. Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT. Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. J Allergy Clin Immunol. 2018 Jul; 142(1):130-138.e1. PMID: 29852258.
      View in: PubMed
    13. Spergel JM, Aceves SS, Kliewer K, Gonsalves N, Chehade M, Wechsler JB, Groetch M, Friedlander J, Dellon ES, Book W, Hirano I, Muir AB, Cianferoni A, Spencer L, Liacouras CA, Cheng E, Kottyan L, Wen T, Platts-Mills T, Rothenberg ME. New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting. J Allergy Clin Immunol. 2018 Jul; 142(1):48-53. PMID: 29803797.
      View in: PubMed
    14. Nhu QM, Aceves SS. Medical and dietary management of eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018 08; 121(2):156-161. PMID: 29753831.
      View in: PubMed
    15. Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, Caldwell JM, Capocelli KE, Carpenter CL, Collins MH, Dellon ES, Eby MD, Gonsalves N, Gupta SK, Falk GW, Hirano I, Menard-Katcher P, Kuhl JT, Krischer JP, Leung J, Mukkada VA, Spergel JM, Trimarchi MP, Yang GY, Zimmermann N, Furuta GT, Rothenberg ME. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. Lancet Gastroenterol Hepatol. 2018 07; 3(7):477-488. PMID: 29730081.
      View in: PubMed
    16. Fahey LM, Chandramouleeswaran PM, Guan S, Benitez AJ, Furuta GT, Aceves SS, Wang ML, Liacouras CA, Muir AB, Sleiman PM, Hakonarson H, Spergel JM, Cianferoni A. Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis. Clin Transl Gastroenterol. 2018 Mar 06; 9(3):139. PMID: 29511165.
      View in: PubMed
    17. Cheng K, Gupta SK, Kantor S, Kuhl JT, Aceves SS, Bonis PA, Capocelli KE, Carpenter C, Chehade M, Collins MH, Dellon ES, Falk GW, Gopal-Srivastava R, Gonsalves N, Hirano I, King EC, Leung J, Krischer JP, Mukkada VA, Schoepfer A, Spergel JM, Straumann A, Yang GY, Furuta GT, Rothenberg ME. Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Transl Sci Rare Dis. 2017 Dec 18; 2(3-4):141-155. PMID: 29333363.
      View in: PubMed
    18. Nhu QM, Aceves SS. Tissue Remodeling in Chronic Eosinophilic Esophageal Inflammation: Parallels in Asthma and Therapeutic Perspectives. Front Med (Lausanne). 2017; 4:128. PMID: 28831387.
      View in: PubMed
    19. O'Shea KM, Aceves SS, Dellon ES, Gupta SK, Spergel JM, Furuta GT, Rothenberg ME. Pathophysiology of Eosinophilic Esophagitis. Gastroenterology. 2018 01; 154(2):333-345. PMID: 28757265.
      View in: PubMed
    20. Furuta GT, Aceves SS. The National Biome Initiative: An allergy perspective. J Allergy Clin Immunol. 2017 04; 139(4):1131-1134. PMID: 28257973.
      View in: PubMed
    21. Aceves SS. Allergy Testing in Patients With Eosinophilic Esophagitis. Gastroenterol Hepatol (N Y). 2016 Aug; 12(8):516-518. PMID: 27917089.
      View in: PubMed
    22. Rawson R, Yang T, Newbury RO, Aquino M, Doshi A, Bell B, Broide DH, Dohil R, Kurten R, Aceves SS. TGF-ß1-induced PAI-1 contributes to a profibrotic network in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2016 09; 138(3):791-800.e4. PMID: 27212082.
      View in: PubMed
    23. Simon D, Cianferoni A, Spergel JM, Aceves S, Holbreich M, Venter C, Rothenberg ME, Terreehorst I, Muraro A, Lucendo AJ, Schoepfer A, Straumann A, Simon HU. Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity. Allergy. 2016 05; 71(5):611-20. PMID: 26799684.
      View in: PubMed
    24. Kliewer KL, Venter C, Cassin AM, Abonia JP, Aceves SS, Bonis PA, Dellon ES, Falk GW, Furuta GT, Gonsalves N, Gupta SK, Hirano I, Kagalwalla A, Leung J, Mukkada VA, Spergel JM, Rothenberg ME. Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet? J Allergy Clin Immunol. 2016 Apr; 137(4):1011-1014. PMID: 26725190; PMCID: PMC4826834 [Available on 04/01/17].
      View in: PubMed, PubMed Central
    25. Rawson R, Anilkumar A, Newbury RO, Bafna V, Aquino M, Palmquist J, Hoffman HM, Mueller JL, Dohil R, Broide DH, Aceves SS. The TGFß1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis. PLoS One. 2015; 10(12):e0144651. PMID: 26656423; PMCID: PMC4678166.
      View in: PubMed, PubMed Central
    26. Safroneeva E, Straumann A, Coslovsky M, Zwahlen M, Kuehni CE, Panczak R, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Schoepfer AM. Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis. Gastroenterology. 2016 Mar; 150(3):581-590.e4. PMID: 26584601.
      View in: PubMed
    27. Tkachenko E, Rawson R, La E, Doherty TA, Baum R, Cavagnero K, Miyanohara A, Dohil R, Kurten RC, Aceves SS. Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression. J Allergy Clin Immunol. 2016 Apr; 137(4):1270-1272.e1. PMID: 26542032.
      View in: PubMed
    28. Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Oct 15; 195(8):3546-56. PMID: 26355153; PMCID: PMC4811198 [Available on 10/15/16].
      View in: PubMed, PubMed Central
    29. Safroneeva E, Coslovsky M, Kuehni CE, Zwahlen M, Haas NA, Panczak R, Taft TH, Hirano I, Dellon ES, Gonsalves N, Leung J, Bussmann C, Woosley JT, Yan P, Romero Y, Furuta GT, Gupta SK, Aceves SS, Chehade M, Straumann A, Schoepfer AM. Eosinophilic oesophagitis: relationship of quality of life with clinical, endoscopic and histological activity. Aliment Pharmacol Ther. 2015 Oct; 42(8):1000-10. PMID: 26271642.
      View in: PubMed
    30. Beppu L, Yang T, Luk M, Newbury RO, Palmquist J, Dohil R, Kurten RC, Broide DH, Aceves SS. MMPs-2 and -14 Are Elevated in Eosinophilic Esophagitis and Reduced Following Topical Corticosteroid Therapy. J Pediatr Gastroenterol Nutr. 2015 Aug; 61(2):194-9. PMID: 25539192; PMCID: PMC4478274.
      View in: PubMed, PubMed Central
    31. Doherty TA, Baum R, Newbury RO, Yang T, Dohil R, Aquino M, Doshi A, Walford HH, Kurten RC, Broide DH, Aceves S. Group 2 innate lymphocytes (ILC2) are enriched in active eosinophilic esophagitis. J Allergy Clin Immunol. 2015 Sep; 136(3):792-794.e3. PMID: 26233928.
      View in: PubMed
    32. Rajan J, Newbury RO, Anilkumar A, Dohil R, Broide DH, Aceves SS. Long-term assessment of esophageal remodeling in patients with pediatric eosinophilic esophagitis treated with topical corticosteroids. J Allergy Clin Immunol. 2016 Jan; 137(1):147-156.e8. PMID: 26233926.
      View in: PubMed
    33. Schoepfer AM, Panczak R, Zwahlen M, Kuehni CE, Coslovsky M, Maurer E, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Blanchard C, Straumann A, Safroneeva E. How do gastroenterologists assess overall activity of eosinophilic esophagitis in adult patients? Am J Gastroenterol. 2015 Mar; 110(3):402-14. PMID: 25732414.
      View in: PubMed
    34. Aceves SS. Reply: To PMID 24035776. Clin Gastroenterol Hepatol. 2015 May; 13(5):1030. PMID: 25737444.
      View in: PubMed
    35. Chehade M, Aceves SS, Furuta GT, Fleischer DM. Food allergy and eosinophilic esophagitis: what do we do? J Allergy Clin Immunol Pract. 2015 Jan-Feb; 3(1):25-32. PMID: 25577614.
      View in: PubMed
    36. Aceves SS. Eosinophilic esophagitis. Immunol Allergy Clin North Am. 2015 Feb; 35(1):145-59. PMID: 25459582.
      View in: PubMed
    37. Sleiman PM, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau K, Bredenoord AJ, Furuta GT, Spergel JM, Hakonarson H. GWAS identifies four novel eosinophilic esophagitis loci. Nat Commun. 2014 Nov 19; 5:5593. PMID: 25407941; PMCID: PMC4238044.
      View in: PubMed, PubMed Central
    38. Banerjee I, Carrion K, Serrano R, Dyo J, Sasik R, Lund S, Willems E, Aceves S, Meili R, Mercola M, Chen J, Zambon A, Hardiman G, Doherty TA, Lange S, del Álamo JC, Nigam V. Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-ß signaling. J Mol Cell Cardiol. 2015 Feb; 79:133-44. PMID: 25446186.
      View in: PubMed
    39. Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME. Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. J Allergy Clin Immunol. 2015 Jan; 135(1):187-97. PMID: 25441638; PMCID: PMC4289084.
      View in: PubMed, PubMed Central
    40. Klinnert MD, Silveira L, Harris R, Moore W, Atkins D, Fleischer DM, Menard-Katcher C, Aceves S, Spergel JM, Franciosi JP, Furuta GT. Health-related quality of life over time in children with eosinophilic esophagitis and their families. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):308-16. PMID: 24897164; PMCID: PMC4141021.
      View in: PubMed, PubMed Central
    41. Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, Nadeau K, Nowak-Wegrzyn A, Oppenheimer J, Perry TT, Randolph C, Sicherer SH, Simon RA, Vickery BP, Wood R, Bernstein D, Blessing-Moore J, Khan D, Lang D, Nicklas R, Oppenheimer J, Portnoy J, Randolph C, Schuller D, Spector S, Tilles SA, Wallace D, Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, Nadeau K, Nowak-Wegrzyn A, Oppenheimer J, Perry TT, Randolph C, Sicherer SH, Simon RA, Vickery BP, Wood R. Food allergy: a practice parameter update-2014. J Allergy Clin Immunol. 2014 Nov; 134(5):1016-25.e43. PMID: 25174862.
      View in: PubMed
    42. Schoepfer AM, Straumann A, Panczak R, Coslovsky M, Kuehni CE, Maurer E, Haas NA, Romero Y, Hirano I, Alexander JA, Gonsalves N, Furuta GT, Dellon ES, Leung J, Collins MH, Bussmann C, Netzer P, Gupta SK, Aceves SS, Chehade M, Moawad FJ, Enders FT, Yost KJ, Taft TH, Kern E, Zwahlen M, Safroneeva E. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology. 2014 Dec; 147(6):1255-66.e21. PMID: 25160980; PMCID: PMC4425255.
      View in: PubMed, PubMed Central
    43. Cho JY, Doshi A, Rosenthal P, Beppu A, Miller M, Aceves S, Broide D. Smad3-deficient mice have reduced esophageal fibrosis and angiogenesis in a model of egg-induced eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2014 Jul; 59(1):10-6. PMID: 24590208; PMCID: PMC4148477.
      View in: PubMed, PubMed Central
    44. Aceves SS. Food and aeroallergens in eosinophilic esophagitis: role of the allergist in patient management. Curr Opin Gastroenterol. 2014 Jul; 30(4):391-5. PMID: 24867155; PMCID: PMC4309387.
      View in: PubMed, PubMed Central
    45. Beppu LY, Anilkumar AA, Newbury RO, Dohil R, Broide DH, Aceves SS. TGF-ß1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Nov; 134(5):1100-1107.e4. PMID: 24835503.
      View in: PubMed
    46. Hirano I, Aceves SS. Clinical implications and pathogenesis of esophageal remodeling in eosinophilic esophagitis. Gastroenterol Clin North Am. 2014 Jun; 43(2):297-316. PMID: 24813517; PMCID: PMC4127387.
      View in: PubMed, PubMed Central
    47. Aceves SS. Remodeling and fibrosis in chronic eosinophil inflammation. Dig Dis. 2014; 32(1-2):15-21. PMID: 24603375; PMCID: PMC4037288.
      View in: PubMed, PubMed Central
    48. Aceves SS. Unmet therapeutic needs in eosinophilic esophagitis. Dig Dis. 2014; 32(1-2):143-8. PMID: 24603399; PMCID: PMC4037231.
      View in: PubMed, PubMed Central
    49. Cho JY, Rosenthal P, Miller M, Pham A, Aceves S, Sakuda S, Broide DH. Targeting AMCase reduces esophageal eosinophilic inflammation and remodeling in a mouse model of egg induced eosinophilic esophagitis. Int Immunopharmacol. 2014 Jan; 18(1):35-42. PMID: 24239745; PMCID: PMC3908829.
      View in: PubMed, PubMed Central
    50. Aceves SS. Food allergy testing in eosinophilic esophagitis: what the gastroenterologist needs to know. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1216-23. PMID: 24035776; PMCID: PMC4048803.
      View in: PubMed, PubMed Central
    51. Greenhawt M, Aceves SS, Spergel JM, Rothenberg ME. The management of eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2013 Jul-Aug; 1(4):332-40; quiz 341-2. PMID: 24565538.
      View in: PubMed
    52. Otani IM, Anilkumar AA, Newbury RO, Bhagat M, Beppu LY, Dohil R, Broide DH, Aceves SS. Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2013 Jun; 131(6):1576-82. PMID: 23623266.
      View in: PubMed
    53. Rothenberg ME, Aceves S, Bonis PA, Collins MH, Gonsalves N, Gupta SK, Hirano I, Liacouras CA, Putnam PE, Spergel JM, Straumann A, Wershil BK, Furuta GT. Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2012 Sep; 130(3):617-9. PMID: 22935588; PMCID: PMC3828675.
      View in: PubMed, PubMed Central
    54. Broderick L, Gandhi C, Mueller JL, Putnam CD, Shayan K, Giclas PC, Peterson KS, Aceves SS, Sheets RM, Peterson BM, Newbury RO, Hoffman HM, Bastian JF. Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis. J Clin Immunol. 2013 Jan; 33(1):162-71. PMID: 22926405; PMCID: PMC3540165.
      View in: PubMed, PubMed Central
    55. Aceves S, Hirano I, Furuta GT, Collins MH. Eosinophilic gastrointestinal diseases--clinically diverse and histopathologically confounding. Semin Immunopathol. 2012 Sep; 34(5):715-31. PMID: 22842863.
      View in: PubMed
    56. Straumann A, Aceves SS, Blanchard C, Collins MH, Furuta GT, Hirano I, Schoepfer AM, Simon D, Simon HU. Pediatric and adult eosinophilic esophagitis: similarities and differences. Allergy. 2012 Apr; 67(4):477-90. PMID: 22313241.
      View in: PubMed
    57. Dohil R, Newbury RO, Aceves S. Transient PPI responsive esophageal eosinophilia may be a clinical sub-phenotype of pediatric eosinophilic esophagitis. Dig Dis Sci. 2012 May; 57(5):1413-9. PMID: 22134787.
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    58. Aceves SS. Tissue remodeling in patients with eosinophilic esophagitis: what lies beneath the surface? J Allergy Clin Immunol. 2011 Nov; 128(5):1047-9. PMID: 22036097.
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    59. Rubinstein E, Cho JY, Rosenthal P, Chao J, Miller M, Pham A, Aceves SS, Varki A, Broide DH. Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2011 Oct; 53(4):409-16. PMID: 21970996; PMCID: PMC3980963.
      View in: PubMed, PubMed Central
    60. Assa'ad AH, Gupta SK, Collins MH, Thomson M, Heath AT, Smith DA, Perschy TL, Jurgensen CH, Ortega HG, Aceves SS. An antibody against IL-5 reduces numbers of esophageal intraepithelial eosinophils in children with eosinophilic esophagitis. Gastroenterology. 2011 Nov; 141(5):1593-604. PMID: 21835135.
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    61. Dohil R, Aceves SS, Dohil MA. Oral viscous budesonide therapy in children with epidermolysis bullosa and proximal esophageal strictures. J Pediatr Gastroenterol Nutr. 2011 Jun; 52(6):776-7. PMID: 21593650.
      View in: PubMed
    62. Liacouras CA, Furuta GT, Hirano I, Atkins D, Attwood SE, Bonis PA, Burks AW, Chehade M, Collins MH, Dellon ES, Dohil R, Falk GW, Gonsalves N, Gupta SK, Katzka DA, Lucendo AJ, Markowitz JE, Noel RJ, Odze RD, Putnam PE, Richter JE, Romero Y, Ruchelli E, Sampson HA, Schoepfer A, Shaheen NJ, Sicherer SH, Spechler S, Spergel JM, Straumann A, Wershil BK, Rothenberg ME, Aceves SS. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. 2011 Jul; 128(1):3-20.e6; quiz 21-2. PMID: 21477849.
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    63. Wolfe JL, Aceves SS. Gastrointestinal manifestations of food allergies. Pediatr Clin North Am. 2011 Apr; 58(2):389-405, x. PMID: 21453809.
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    64. Aceves SS, Chen D, Newbury RO, Dohil R, Bastian JF, Broide DH. Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-ß1, and increase esophageal smooth muscle contraction. J Allergy Clin Immunol. 2010 Dec; 126(6):1198-204.e4. PMID: 21047675.
      View in: PubMed
    65. Chehade M, Aceves SS. Food allergy and eosinophilic esophagitis. Curr Opin Allergy Clin Immunol. 2010 Jun; 10(3):231-7. PMID: 20410819.
      View in: PubMed
    66. Dohil R, Newbury R, Fox L, Bastian J, Aceves S. Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial. Gastroenterology. 2010 Aug; 139(2):418-29. PMID: 20457157.
      View in: PubMed
    67. Caldwell JM, Blanchard C, Collins MH, Putnam PE, Kaul A, Aceves SS, Bouska CA, Rothenberg ME. Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. J Allergy Clin Immunol. 2010 Apr; 125(4):879-888.e8. PMID: 20371398; PMCID: PMC2865682.
      View in: PubMed, PubMed Central
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