Seema Aceves

Title(s)Professor Of Clinical, Pediatrics
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    UC San DiegoMD, PhDMedical Scientist Training Program

    Collapse Overview 
    Collapse Overview
    Dr. Aceves completed both her medical degree and her PhD through the Medical Scientist Training Program at UC San Diego. She also completed her pediatric internship, residency and a fellowship in allergy and immunology at UC San Diego.

    Dr. Aceves was named a Physician of Exceptional Excellence in the 2012 "San Diego's Top Doctors" survey from the San Diego County Medical Society and San Diego Magazine.

    She was elected to the American Society for Clinical Investigation in 2013.

    Collapse Research 
    Collapse Research Activities and Funding
    Probing the Mechanisms of Fibroblast-Extracellular Matrix Interactions to Assess Disease Severity in Allergic Eosinophilic Esophagitis
    NIH R21AI154353May 22, 2020 - Apr 30, 2022
    Role: Principal Investigator
    LIGHT/TNFSF14 in allergic esophagitis remodeling
    NIH R01DK114457Apr 1, 2018 - Feb 28, 2022
    Role: Co-Principal Investigator
    Mentoring Patient Oriented Research in Allergic Eosinophilic Gastrointestinal Disorders
    NIH K24AI135034Dec 12, 2017 - Nov 30, 2022
    Role: Principal Investigator
    Consortium of Eosinophilic Gastrointestinal Disease Researchers
    NIH U54AI117804Aug 15, 2014 - Jul 31, 2019
    Role: Co-Investigator
    Contribution of rigid matrix to allergic eosinophilic esophagitis pathogenesis
    NIH R01AI092135Jul 1, 2011 - Jun 30, 2021
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Development of a Core Outcome Set for Therapeutic Studies in Eosinophilic Esophagitis (COREOS). J Allergy Clin Immunol. 2021 Jul 06. COREOS Collaborators , Ma C, Schoepfer AM, Dellon ES, Bredenoord AJ, Chehade M, Collins MH, Feagan BG, Furuta GT, Gupta SK, Hirano I, Jairath V, Katzka DA, Pai RK, Rothenberg ME, Straumann A, Aceves SS, Alexander JA, Arva NC, Atkins D, Biedermann L, Blanchard C, Cianferoni A, Ciriza de Los Rios C, Clayton F, Davis CM, de Bortoli N, Dias JA, Falk GW, Genta RM, Ghaffari G, Gonsalves N, Greuter T, Hopp R, Hsu Blatman KS, Jensen ET, Johnston D, Kagalwalla AF, Larsson HM, Leung J, Louis H, Masterson JC, Menard-Katcher C, Menard-Katcher PA, Moawad FJ, Muir AB, Mukkada VA, Penagini R, Pesek RD, Peterson K, Putnam PE, Ravelli A, Savarino EV, Schlag C, Schreiner P, Simon D, Smyrk TC, Spergel JM, Taft TH, Terreehorst I, Vanuytsel T, Venter C, Vieira MC, Vieth M, Vlieg-Boerstra B, von Arnim U, Walker MM, Wechsler JB, Woodland P, Woosley JT, Yang GY, Zevit N, Safroneeva E. PMID: 34242635.
      View in: PubMed   Mentions:    Fields:    
    2. The role of the allergist in the management of eosinophilic esophagitis. Curr Opin Gastroenterol. 2021 Jul 01; 37(4):390-396. Woo W, Aceves SS. PMID: 34059605.
      View in: PubMed   Mentions:    Fields:    
    3. Long-Lasting Dissociation of Esophageal Eosinophilia and Symptoms Following Dilation in Adults with Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2021 May 29. Safroneeva E, Pan Z, King E, Martin LJ, Collins MH, Yang GY, Capocelli KE, Arva NC, Abonia JP, Atkins D, Bonis PA, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Leung J, Menard-Katcher PA, Mukkada VA, Schoepfer AM, Spergel JM, Wershil BK, Rothenberg ME, Aceves SS, Furuta GT, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 34062314.
      View in: PubMed   Mentions:    Fields:    
    4. Type 2 Immunity and Age Modify Gene Expression of Coronavirus-induced Disease 2019 Receptors in Eosinophilic Gastrointestinal Disorders. J Pediatr Gastroenterol Nutr. 2021 05 01; 72(5):718-722. Chiang AWT, Duong LD, Shoda T, Nhu QM, Ruffner M, Hara T, Aaron B, Joplin E, Manresa MC, Abonia JP, Dellon ES, Hirano I, Gonsalves N, Gupta SK, Furuta GT, Rothenberg ME, Lewis NE, Muir AB, Aceves SS, CEGIR Investigator Group . PMID: 33394891.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis. J Allergy Clin Immunol. 2021 Feb 06. Hsieh LY, Chiang AWT, Duong LD, Kuo CC, Dong SX, Dohil R, Kurten R, Lewis NE, Aceves SS. PMID: 33556465.
      View in: PubMed   Mentions:    Fields:    
    6. Multiplexed Functional Assessment of Genetic Variants in CARD11. Am J Hum Genet. 2020 12 03; 107(6):1029-1043. Meitlis I, Allenspach EJ, Bauman BM, Phan IQ, Dabbah G, Schmitt EG, Camp ND, Torgerson TR, Nickerson DA, Bamshad MJ, Hagin D, Luthers CR, Stinson JR, Gray J, Lundgren I, Church JA, Butte MJ, Jordan MB, Aceves SS, Schwartz DM, Milner JD, Schuval S, Skoda-Smith S, Cooper MA, Starita LM, Rawlings DJ, Snow AL, James RG. PMID: 33202260.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    7. High Patient Disease Burden in a Cross-sectional, Multicenter Contact Registry Study of Eosinophilic Gastrointestinal Diseases. J Pediatr Gastroenterol Nutr. 2020 10; 71(4):524-529. Jensen ET, Aceves SS, Bonis PA, Bray K, Book W, Chehade M, Collins MH, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Katzka DA, Kyle S, Mack D, Kodroff E, Leung J, Mukkada VA, Scott M, Paliana A, Sable K, Spergel JM, Strobel MJ, Krischer J, Rothenberg ME, Abonia P, CEGIR Investigator group . PMID: 32541201.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    8. Plasminogen Activator Inhibitor-1 as a Marker of Esophageal Functional Changes in Pediatric Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2020 Sep 30. Williamson P, Proudfoot J, Gharibans A, Dohil L, Newbury R, Barsamian J, Hassan M, Rawson R, Katzka D, Kurten R, Dohil R, Mousa H, Aceves S. PMID: 33007513.
      View in: PubMed   Mentions: 1     Fields:    
    9. Increased Production of LIGHT by T Cells in Eosinophilic Esophagitis Promotes Differentiation of Esophageal Fibroblasts Toward an Inflammatory Phenotype. Gastroenterology. 2020 11; 159(5):1778-1792.e13. Manresa MC, Chiang AWT, Kurten RC, Dohil R, Brickner H, Dohil L, Herro R, Akuthota P, Lewis NE, Croft M, Aceves SS. PMID: 32712105.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    10. Challenges with the technical review of eosinophilic esophagitis: discussion points for the practicing allergist. Ann Allergy Asthma Immunol. 2020 05; 124(5):411-413. Spergel JM, Aceves SS, Greenhawt M. PMID: 32336460.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    11. Technical review on the management of eosinophilic esophagitis: a report from the AGA institute and the joint task force on allergy-immunology practice parameters. Ann Allergy Asthma Immunol. 2020 05; 124(5):424-440.e17. Rank MA, Sharaf RN, Furuta GT, Aceves SS, Greenhawt M, Spergel JM, Falck-Ytter YT, Dellon ES, AGA Institute. Electronic address: clinicalpractice@gastro.org , Joint Task Force on Allergy-Immunology Practice Parameters collaborators. Electronic address: drdana , AGA Institute , Joint Task Force on Allergy-Immunology Practice Parameters collaborators . PMID: 32336463.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    12. Technical Review on the Management of Eosinophilic Esophagitis: A Report From the AGA Institute and the Joint Task Force on Allergy-Immunology Practice Parameters. Gastroenterology. 2020 05; 158(6):1789-1810.e15. Rank MA, Sharaf RN, Furuta GT, Aceves SS, Greenhawt M, Spergel JM, Falck-Ytter YT, Dellon ES, AGA Institute. Electronic address: clinicalpractice@gastro.org , Joint Task Force on Allergy-Immunology Practice Parameters collaborators. Electronic address: drdana , AGA Institute , Joint Task Force on Allergy-Immunology Practice Parameters collaborators . PMID: 32359563.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    13. Antifibrotic Effects of the Thiazolidinediones in Eosinophilic Esophagitis Pathologic Remodeling: A Preclinical Evaluation. Clin Transl Gastroenterol. 2020 04; 11(4):e00164. Nhu QM, Hsieh L, Dohil L, Dohil R, Newbury RO, Kurten R, Moawad FJ, Aceves SS. PMID: 32352681.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    14. Esophageal type 2 cytokine expression heterogeneity in eosinophilic esophagitis in a multisite cohort. J Allergy Clin Immunol. 2020 06; 145(6):1629-1640.e4. Dunn JLM, Shoda T, Caldwell JM, Wen T, Aceves SS, Collins MH, Dellon ES, Falk GW, Leung J, Martin LJ, Menard-Katcher P, Rudman-Spergel AK, Spergel JM, Wechsler JB, Yang GY, Furuta GT, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 32197970.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    15. Modeling Epithelial Homeostasis and Reactive Epithelial Changes in Human and Murine Three-Dimensional Esophageal Organoids. Curr Protoc Stem Cell Biol. 2020 03; 52(1):e106. Nakagawa H, Kasagi Y, Karakasheva TA, Hara T, Aaron B, Shimonosono M, Kijima T, Giroux V, Bailey D, Wilkins B, Abrams JA, Falk GW, Aceves SS, Spergel JM, Hamilton KE, Whelan KA, Muir AB. PMID: 32105412.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    16. Diagnosis and treatment of eosinophilic esophagitis. J Allergy Clin Immunol. 2020 01; 145(1):1-7. Gonsalves NP, Aceves SS. PMID: 31910983.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    17. The potential for malignancy from atopic disorders and allergic inflammation: A systematic review and meta-analysis. Clin Exp Allergy. 2020 02; 50(2):147-159. Muir AB, Whelan KA, Dougherty MK, Aaron B, Navarre B, Aceves SS, Dellon ES, Jensen ET. PMID: 31743536.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    18. Unanswered questions in eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2020 03; 124(3):227-228. Nhu QM, Aceves SS. PMID: 31821874.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    19. Use of hPSC-derived 3D organoids and mouse genetics to define the roles of YAP in the development of the esophagus. Development. 2019 12 04; 146(23). Bailey DD, Zhang Y, van Soldt BJ, Jiang M, Suresh S, Nakagawa H, Rustgi AK, Aceves SS, Cardoso WV, Que J. PMID: 31748205.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    20. Symptom Burden and Quality of Life Over Time in Pediatric Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 12; 69(6):682-689. Klinnert MD, Atkins D, Pan Z, Franciosi JP, Aceves SS, Spergel JM, Furuta GT. PMID: 31436703.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    21. Allergies and Eosinophilic Esophagitis-Current Updates for the Pediatric Gastroenterologist. Curr Gastroenterol Rep. 2019 Nov 20; 21(11):56. Williamson P, Aceves S. PMID: 31748971.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansPHPublic Health
    22. Advancing patient care through the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). J Allergy Clin Immunol. 2020 01; 145(1):28-37. Aceves S, Collins MH, Rothenberg ME, Furuta GT, Gonsalves N, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 31758958.
      View in: PubMed   Mentions:    Fields:    
    23. Molecular, endoscopic, histologic, and circulating biomarker-based diagnosis of eosinophilic gastritis: Multi-site study. J Allergy Clin Immunol. 2020 01; 145(1):255-269. Shoda T, Wen T, Caldwell JM, Collins MH, Besse JA, Osswald GA, Abonia JP, Arva NC, Atkins D, Capocelli KE, Dellon ES, Falk GW, Gonsalves N, Gupta SK, Hirano I, Mukkada VA, Putnam PE, Sheridan RM, Rudman Spergel AK, Spergel JM, Wechsler JB, Yang GY, Aceves SS, Furuta GT, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 31738990.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCTClinical Trials
    24. Evaluation of long-term course in children with eosinophilic esophagitis reveals distinct histologic patterns and clinical characteristics. J Allergy Clin Immunol. 2019 10; 144(4):1050-1057.e5. Collins CA, Palmquist J, Proudfoot JA, Qian A, Wangberg H, Khosh-Hemmat E, Dohil R, Aceves SS. PMID: 31255641.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    25. Local Antigen Deposition in Eosinophilic Esophagitis: Implications for Immune Activation. Gastroenterology. 2019 07; 157(1):17-20. Aceves SS. PMID: 31150607.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansAnimals
    26. Development and Application of a Functional Human Esophageal Mucosa Explant Platform to Eosinophilic Esophagitis. Sci Rep. 2019 04 17; 9(1):6206. Kurten RC, Rawson R, Shoda T, Duong LD, Adejumobi D, Levy R, Newbury RO, Rothenberg ME, Akuthota P, Wright BL, Dohil R, Jones SM, Aceves SS. PMID: 30996235.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    27. Esophageal Compliance Quantifies Epithelial Remodeling in Pediatric Patients With Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 04; 68(4):559-565. Hassan M, Aceves S, Dohil R, Gharibans A, Newbury R, Proudfoot J, Mousa H. PMID: 30418408.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    28. Overestimation of the diagnosis of eosinophilic colitis with reliance on billing codes. J Allergy Clin Immunol Pract. 2019 Sep - Oct; 7(7):2434-2436. Muir AB, Jensen ET, Wechsler JB, Menard-Katcher P, Falk GW, Aceves SS, Furuta GT, Dellon ES, Rothenberg ME, Spergel JM. PMID: 30922989.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    29. Interleukin 9 Alters Epithelial Barrier and E-cadherin in Eosinophilic Esophagitis. J Pediatr Gastroenterol Nutr. 2019 02; 68(2):225-231. Doshi A, Khamishon R, Rawson R, Duong L, Dohil L, Myers SJ, Bell B, Dohil R, Newbury RO, Barrett KE, Kurten RC, Aceves SS. PMID: 30211842.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansCells
    30. Variation in Endoscopic Activity Assessment and Endoscopy Score Validation in Adults With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol. 2019 07; 17(8):1477-1488.e10. Schoepfer AM, Hirano I, Coslovsky M, Roumet MC, Zwahlen M, Kuehni CE, Hafner D, Alexander JA, Dellon ES, Gonsalves N, Leung J, Bussmann C, Collins MH, Newbury RO, Smyrk TC, Woosley JT, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Falk GW, Meltzer BA, Comer GM, Straumann A, Safroneeva E, International EEsAI Study Group . PMID: 30476587.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    31. Consortium of Eosinophilic Gastrointestinal Disease Researchers: Advancing the Field of Eosinophilic GI Disorders Through Collaboration. Gastroenterology. 2019 03; 156(4):838-842. Gupta SK, Falk GW, Aceves SS, Chehade M, Collins MH, Dellon ES, Gonsalves N, Hirano I, Mukkuda VA, Peterson KA, Spergel J, Yang GY, Furuta GT, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 30452923.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    32. Updated International Consensus Diagnostic Criteria for Eosinophilic Esophagitis: Proceedings of the AGREE Conference. Gastroenterology. 2018 10; 155(4):1022-1033.e10. Dellon ES, Liacouras CA, Molina-Infante J, Furuta GT, Spergel JM, Zevit N, Spechler SJ, Attwood SE, Straumann A, Aceves SS, Alexander JA, Atkins D, Arva NC, Blanchard C, Bonis PA, Book WM, Capocelli KE, Chehade M, Cheng E, Collins MH, Davis CM, Dias JA, Di Lorenzo C, Dohil R, Dupont C, Falk GW, Ferreira CT, Fox A, Gonsalves NP, Gupta SK, Katzka DA, Kinoshita Y, Menard-Katcher C, Kodroff E, Metz DC, Miehlke S, Muir AB, Mukkada VA, Murch S, Nurko S, Ohtsuka Y, Orel R, Papadopoulou A, Peterson KA, Philpott H, Putnam PE, Richter JE, Rosen R, Rothenberg ME, Schoepfer A, Scott MM, Shah N, Sheikh J, Souza RF, Strobel MJ, Talley NJ, Vaezi MF, Vandenplas Y, Vieira MC, Walker MM, Wechsler JB, Wershil BK, Wen T, Yang GY, Hirano I, Bredenoord AJ. PMID: 30009819.
      View in: PubMed   Mentions: 104     Fields:    Translation:Humans
    33. Allergic components of eosinophilic esophagitis. J Allergy Clin Immunol. 2018 07; 142(1):1-8. Spergel J, Aceves SS. PMID: 29980277.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    34. Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 11; 16(11):1714-1729.e3. Ma C, van Rhijn BD, Jairath V, Nguyen TM, Parker CE, Aceves SS, Furuta GT, Gupta SK, Katzka DA, Safroneeva E, Schoepfer AM, Straumann A, Spergel JM, Pai RK, Feagan BG, Hirano I, Dellon ES, Bredenoord AJ. PMID: 29908360.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    35. Alignment of parent- and child-reported outcomes and histology in eosinophilic esophagitis across multiple CEGIR sites. J Allergy Clin Immunol. 2018 07; 142(1):130-138.e1. Aceves SS, King E, Collins MH, Yang GY, Capocelli KE, Abonia JP, Atkins D, Bonis PA, Carpenter CL, Dellon ES, Eby MD, Falk GW, Gonsalves N, Gupta SK, Hirano I, Kocher K, Krischer JP, Leung J, Lipscomb J, Menard-Katcher P, Mukkada VA, Pan Z, Spergel JM, Sun Q, Wershil BK, Rothenberg ME, Furuta GT, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 29852258.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    36. New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting. J Allergy Clin Immunol. 2018 07; 142(1):48-53. Spergel JM, Aceves SS, Kliewer K, Gonsalves N, Chehade M, Wechsler JB, Groetch M, Friedlander J, Dellon ES, Book W, Hirano I, Muir AB, Cianferoni A, Spencer L, Liacouras CA, Cheng E, Kottyan L, Wen T, Platts-Mills T, Rothenberg ME. PMID: 29803797.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    37. Medical and dietary management of eosinophilic esophagitis. Ann Allergy Asthma Immunol. 2018 08; 121(2):156-161. Nhu QM, Aceves SS. PMID: 29753831.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    38. Eosinophilic oesophagitis endotype classification by molecular, clinical, and histopathological analyses: a cross-sectional study. Lancet Gastroenterol Hepatol. 2018 07; 3(7):477-488. Shoda T, Wen T, Aceves SS, Abonia JP, Atkins D, Bonis PA, Caldwell JM, Capocelli KE, Carpenter CL, Collins MH, Dellon ES, Eby MD, Gonsalves N, Gupta SK, Falk GW, Hirano I, Menard-Katcher P, Kuhl JT, Krischer JP, Leung J, Mukkada VA, Spergel JM, Trimarchi MP, Yang GY, Zimmermann N, Furuta GT, Rothenberg ME, Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) . PMID: 29730081.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    39. Food allergen triggers are increased in children with the TSLP risk allele and eosinophilic esophagitis. Clin Transl Gastroenterol. 2018 Mar 06; 9(3):139. Fahey LM, Chandramouleeswaran PM, Guan S, Benitez AJ, Furuta GT, Aceves SS, Wang ML, Liacouras CA, Muir AB, Sleiman PM, Hakonarson H, Spergel JM, Cianferoni A. PMID: 29511165.
      View in: PubMed   Mentions: 10     Fields:    
    40. Creating a multi-center rare disease consortium - the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR). Transl Sci Rare Dis. 2017 Dec 18; 2(3-4):141-155. Cheng K, Gupta SK, Kantor S, Kuhl JT, Aceves SS, Bonis PA, Capocelli KE, Carpenter C, Chehade M, Collins MH, Dellon ES, Falk GW, Gopal-Srivastava R, Gonsalves N, Hirano I, King EC, Leung J, Krischer JP, Mukkada VA, Schoepfer A, Spergel JM, Straumann A, Yang GY, Furuta GT, Rothenberg ME. PMID: 29333363.
      View in: PubMed   Mentions:
    41. Tissue Remodeling in Chronic Eosinophilic Esophageal Inflammation: Parallels in Asthma and Therapeutic Perspectives. Front Med (Lausanne). 2017; 4:128. Nhu QM, Aceves SS. PMID: 28831387.
      View in: PubMed   Mentions:
    42. Pathophysiology of Eosinophilic Esophagitis. Gastroenterology. 2018 01; 154(2):333-345. O'Shea KM, Aceves SS, Dellon ES, Gupta SK, Spergel JM, Furuta GT, Rothenberg ME. PMID: 28757265.
      View in: PubMed   Mentions: 53     Fields:    Translation:HumansCells
    43. The National Biome Initiative: An allergy perspective. J Allergy Clin Immunol. 2017 04; 139(4):1131-1134. Furuta GT, Aceves SS. PMID: 28257973.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    44. Allergy Testing in Patients With Eosinophilic Esophagitis. Gastroenterol Hepatol (N Y). 2016 Aug; 12(8):516-518. Aceves SS. PMID: 27917089.
      View in: PubMed   Mentions:
    45. TGF-ß1-induced PAI-1 contributes to a profibrotic network in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2016 09; 138(3):791-800.e4. Rawson R, Yang T, Newbury RO, Aquino M, Doshi A, Bell B, Broide DH, Dohil R, Kurten R, Aceves SS. PMID: 27212082.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansCells
    46. Should wheat, barley, rye, and/or gluten be avoided in a 6-food elimination diet? J Allergy Clin Immunol. 2016 Apr; 137(4):1011-1014. Kliewer KL, Venter C, Cassin AM, Abonia JP, Aceves SS, Bonis PA, Dellon ES, Falk GW, Furuta GT, Gonsalves N, Gupta SK, Hirano I, Kagalwalla A, Leung J, Mukkada VA, Spergel JM, Rothenberg ME. PMID: 26725190.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    47. The TGFß1 Promoter SNP C-509T and Food Sensitization Promote Esophageal Remodeling in Pediatric Eosinophilic Esophagitis. PLoS One. 2015; 10(12):e0144651. Rawson R, Anilkumar A, Newbury RO, Bafna V, Aquino M, Palmquist J, Hoffman HM, Mueller JL, Dohil R, Broide DH, Aceves SS. PMID: 26656423.
      View in: PubMed   Mentions: 14     Fields:    Translation:HumansCells
    48. Symptoms Have Modest Accuracy in Detecting Endoscopic and Histologic Remission in Adults With Eosinophilic Esophagitis. Gastroenterology. 2016 Mar; 150(3):581-590.e4. Safroneeva E, Straumann A, Coslovsky M, Zwahlen M, Kuehni CE, Panczak R, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Spergel JM, Schoepfer AM, International Eosinophilic Esophagitis Activity Index Study Group . PMID: 26584601.
      View in: PubMed   Mentions: 61     Fields:    Translation:HumansCells
    49. Rigid substrate induces esophageal smooth muscle hypertrophy and eosinophilic esophagitis fibrotic gene expression. J Allergy Clin Immunol. 2016 Apr; 137(4):1270-1272.e1. Tkachenko E, Rawson R, La E, Doherty TA, Baum R, Cavagnero K, Miyanohara A, Dohil R, Kurten RC, Aceves SS. PMID: 26542032.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    50. Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Oct 15; 195(8):3546-56. Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. PMID: 26355153.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    51. Long-term assessment of esophageal remodeling in patients with pediatric eosinophilic esophagitis treated with topical corticosteroids. J Allergy Clin Immunol. 2016 Jan; 137(1):147-156.e8. Rajan J, Newbury RO, Anilkumar A, Dohil R, Broide DH, Aceves SS. PMID: 26233926.
      View in: PubMed   Mentions: 25     Fields:    Translation:Humans
    52. Group 2 innate lymphocytes (ILC2) are enriched in active eosinophilic esophagitis. J Allergy Clin Immunol. 2015 Sep; 136(3):792-794.e3. Doherty TA, Baum R, Newbury RO, Yang T, Dohil R, Aquino M, Doshi A, Walford HH, Kurten RC, Broide DH, Aceves S. PMID: 26233928.
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    53. How do gastroenterologists assess overall activity of eosinophilic esophagitis in adult patients? Am J Gastroenterol. 2015 Mar; 110(3):402-14. Schoepfer AM, Panczak R, Zwahlen M, Kuehni CE, Coslovsky M, Maurer E, Haas NA, Alexander JA, Dellon ES, Gonsalves N, Hirano I, Leung J, Bussmann C, Collins MH, Newbury RO, De Petris G, Smyrk TC, Woosley JT, Yan P, Yang GY, Romero Y, Katzka DA, Furuta GT, Gupta SK, Aceves SS, Chehade M, Blanchard C, Straumann A, Safroneeva E, International EEsAI Study Group . PMID: 25732414.
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    54. Reply: To PMID 24035776. Clin Gastroenterol Hepatol. 2015 May; 13(5):1030. Aceves SS. PMID: 25737444.
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    55. Food allergy and eosinophilic esophagitis: what do we do? J Allergy Clin Immunol Pract. 2015 Jan-Feb; 3(1):25-32. Chehade M, Aceves SS, Furuta GT, Fleischer DM. PMID: 25577614.
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    56. Phocine distemper virus: current knowledge and future directions. Viruses. 2014 Dec 22; 6(12):5093-134. Duignan PJ, Van Bressem MF, Baker JD, Barbieri M, Colegrove KM, De Guise S, de Swart RL, Di Guardo G, Dobson A, Duprex WP, Early G, Fauquier D, Goldstein T, Goodman SJ, Grenfell B, Groch KR, Gulland F, Hall A, Jensen BA, Lamy K, Matassa K, Mazzariol S, Morris SE, Nielsen O, Rotstein D, Rowles TK, Saliki JT, Siebert U, Waltzek T, Wellehan JF. PMID: 25539192.
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    57. Eosinophilic esophagitis. Immunol Allergy Clin North Am. 2015 Feb; 35(1):145-59. Aceves SS. PMID: 25459582.
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    58. GWAS identifies four novel eosinophilic esophagitis loci. Nat Commun. 2014 Nov 19; 5:5593. Sleiman PM, Wang ML, Cianferoni A, Aceves S, Gonsalves N, Nadeau K, Bredenoord AJ, Furuta GT, Spergel JM, Hakonarson H. PMID: 25407941.
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    59. Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-ß signaling. J Mol Cell Cardiol. 2015 Feb; 79:133-44. Banerjee I, Carrion K, Serrano R, Dyo J, Sasik R, Lund S, Willems E, Aceves S, Meili R, Mercola M, Chen J, Zambon A, Hardiman G, Doherty TA, Lange S, del Álamo JC, Nigam V. PMID: 25446186.
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    60. Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. J Allergy Clin Immunol. 2015 Jan; 135(1):187-97. Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME. PMID: 25441638.
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    61. Health-related quality of life over time in children with eosinophilic esophagitis and their families. J Pediatr Gastroenterol Nutr. 2014 Sep; 59(3):308-16. Klinnert MD, Silveira L, Harris R, Moore W, Atkins D, Fleischer DM, Menard-Katcher C, Aceves S, Spergel JM, Franciosi JP, Furuta GT. PMID: 24897164.
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    62. Food allergy: a practice parameter update-2014. J Allergy Clin Immunol. 2014 Nov; 134(5):1016-25.e43. Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, Nadeau K, Nowak-Wegrzyn A, Oppenheimer J, Perry TT, Randolph C, Sicherer SH, Simon RA, Vickery BP, Wood R, Joint Task Force on Practice Parameters , Bernstein D, Blessing-Moore J, Khan D, Lang D, Nicklas R, Oppenheimer J, Portnoy J, Randolph C, Schuller D, Spector S, Tilles SA, Wallace D, Practice Parameter Workgroup , Sampson HA, Aceves S, Bock SA, James J, Jones S, Lang D, Nadeau K, Nowak-Wegrzyn A, Oppenheimer J, Perry TT, Randolph C, Sicherer SH, Simon RA, Vickery BP, Wood R. PMID: 25174862.
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    63. Development and validation of a symptom-based activity index for adults with eosinophilic esophagitis. Gastroenterology. 2014 Dec; 147(6):1255-66.e21. Schoepfer AM, Straumann A, Panczak R, Coslovsky M, Kuehni CE, Maurer E, Haas NA, Romero Y, Hirano I, Alexander JA, Gonsalves N, Furuta GT, Dellon ES, Leung J, Collins MH, Bussmann C, Netzer P, Gupta SK, Aceves SS, Chehade M, Moawad FJ, Enders FT, Yost KJ, Taft TH, Kern E, Zwahlen M, Safroneeva E, International Eosinophilic Esophagitis Activity Index Study Group . PMID: 25160980.
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    64. Food and aeroallergens in eosinophilic esophagitis: role of the allergist in patient management. Curr Opin Gastroenterol. 2014 Jul; 30(4):391-5. Aceves SS. PMID: 24867155.
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    65. Smad3-deficient mice have reduced esophageal fibrosis and angiogenesis in a model of egg-induced eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2014 Jul; 59(1):10-6. Cho JY, Doshi A, Rosenthal P, Beppu A, Miller M, Aceves S, Broide D. PMID: 24590208.
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    66. TGF-ß1-induced phospholamban expression alters esophageal smooth muscle cell contraction in patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2014 Nov; 134(5):1100-1107.e4. Beppu LY, Anilkumar AA, Newbury RO, Dohil R, Broide DH, Aceves SS. PMID: 24835503.
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    67. Clinical implications and pathogenesis of esophageal remodeling in eosinophilic esophagitis. Gastroenterol Clin North Am. 2014 Jun; 43(2):297-316. Hirano I, Aceves SS. PMID: 24813517.
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    68. Remodeling and fibrosis in chronic eosinophil inflammation. Dig Dis. 2014; 32(1-2):15-21. Aceves SS. PMID: 24603375.
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    69. Unmet therapeutic needs in eosinophilic esophagitis. Dig Dis. 2014; 32(1-2):143-8. Aceves SS. PMID: 24603399.
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    70. Sleeve lobectomy for non-small cell lung cancer with N1 nodal disease does not compromise survival. Ann Thorac Surg. 2014 Jan; 97(1):230-5. Berry MF, Worni M, Wang X, Harpole DH, D'Amico TA, Onaitis MW. PMID: 24239745.
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    71. Food allergy testing in eosinophilic esophagitis: what the gastroenterologist needs to know. Clin Gastroenterol Hepatol. 2014 Aug; 12(8):1216-23. Aceves SS. PMID: 24035776.
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    72. The management of eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2013 Jul-Aug; 1(4):332-40; quiz 341-2. Greenhawt M, Aceves SS, Spergel JM, Rothenberg ME. PMID: 24565538.
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    73. Anti-IL-5 therapy reduces mast cell and IL-9 cell numbers in pediatric patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2013 Jun; 131(6):1576-82. Otani IM, Anilkumar AA, Newbury RO, Bhagat M, Beppu LY, Dohil R, Broide DH, Aceves SS. PMID: 23623266.
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    74. Working with the US Food and Drug Administration: progress and timelines in understanding and treating patients with eosinophilic esophagitis. J Allergy Clin Immunol. 2012 Sep; 130(3):617-9. Rothenberg ME, Aceves S, Bonis PA, Collins MH, Gonsalves N, Gupta SK, Hirano I, Liacouras CA, Putnam PE, Spergel JM, Straumann A, Wershil BK, Furuta GT. PMID: 22935588.
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    75. Mutations of complement factor I and potential mechanisms of neuroinflammation in acute hemorrhagic leukoencephalitis. J Clin Immunol. 2013 Jan; 33(1):162-71. Broderick L, Gandhi C, Mueller JL, Putnam CD, Shayan K, Giclas PC, Peterson KS, Aceves SS, Sheets RM, Peterson BM, Newbury RO, Hoffman HM, Bastian JF. PMID: 22926405.
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    76. Eosinophilic gastrointestinal diseases--clinically diverse and histopathologically confounding. Semin Immunopathol. 2012 Sep; 34(5):715-31. Aceves S, Hirano I, Furuta GT, Collins MH. PMID: 22842863.
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    77. Transient PPI responsive esophageal eosinophilia may be a clinical sub-phenotype of pediatric eosinophilic esophagitis. Dig Dis Sci. 2012 May; 57(5):1413-9. Dohil R, Newbury RO, Aceves S. PMID: 22134787.
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    78. Tissue remodeling in patients with eosinophilic esophagitis: what lies beneath the surface? J Allergy Clin Immunol. 2011 Nov; 128(5):1047-9. Aceves SS. PMID: 22036097.
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    79. Siglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2011 Oct; 53(4):409-16. Rubinstein E, Cho JY, Rosenthal P, Chao J, Miller M, Pham A, Aceves SS, Varki A, Broide DH. PMID: 21970996.
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    80. An antibody against IL-5 reduces numbers of esophageal intraepithelial eosinophils in children with eosinophilic esophagitis. Gastroenterology. 2011 Nov; 141(5):1593-604. Assa'ad AH, Gupta SK, Collins MH, Thomson M, Heath AT, Smith DA, Perschy TL, Jurgensen CH, Ortega HG, Aceves SS. PMID: 21835135.
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    81. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol. 2011 Jul; 128(1):3-20.e6; quiz 21-2. Liacouras CA, Furuta GT, Hirano I, Atkins D, Attwood SE, Bonis PA, Burks AW, Chehade M, Collins MH, Dellon ES, Dohil R, Falk GW, Gonsalves N, Gupta SK, Katzka DA, Lucendo AJ, Markowitz JE, Noel RJ, Odze RD, Putnam PE, Richter JE, Romero Y, Ruchelli E, Sampson HA, Schoepfer A, Shaheen NJ, Sicherer SH, Spechler S, Spergel JM, Straumann A, Wershil BK, Rothenberg ME, Aceves SS. PMID: 21477849.
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    82. Gastrointestinal manifestations of food allergies. Pediatr Clin North Am. 2011 Apr; 58(2):389-405, x. Wolfe JL, Aceves SS. PMID: 21453809.
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    83. Mast cells infiltrate the esophageal smooth muscle in patients with eosinophilic esophagitis, express TGF-ß1, and increase esophageal smooth muscle contraction. J Allergy Clin Immunol. 2010 Dec; 126(6):1198-204.e4. Aceves SS, Chen D, Newbury RO, Dohil R, Bastian JF, Broide DH. PMID: 21047675.
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    84. Food allergy and eosinophilic esophagitis. Curr Opin Allergy Clin Immunol. 2010 Jun; 10(3):231-7. Chehade M, Aceves SS. PMID: 20410819.
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    85. Oral viscous budesonide is effective in children with eosinophilic esophagitis in a randomized, placebo-controlled trial. Gastroenterology. 2010 Aug; 139(2):418-29. Dohil R, Newbury R, Fox L, Bastian J, Aceves S. PMID: 20457157.
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    86. Glucocorticoid-regulated genes in eosinophilic esophagitis: a role for FKBP51. J Allergy Clin Immunol. 2010 Apr; 125(4):879-888.e8. Caldwell JM, Blanchard C, Collins MH, Putnam PE, Kaul A, Aceves SS, Bouska CA, Rothenberg ME. PMID: 20371398.
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    87. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. Nat Genet. 2010 Apr; 42(4):289-91. Rothenberg ME, Spergel JM, Sherrill JD, Annaiah K, Martin LJ, Cianferoni A, Gober L, Kim C, Glessner J, Frackelton E, Thomas K, Blanchard C, Liacouras C, Verma R, Aceves S, Collins MH, Brown-Whitehorn T, Putnam PE, Franciosi JP, Chiavacci RM, Grant SF, Abonia JP, Sleiman PM, Hakonarson H. PMID: 20208534.
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    88. A symptom scoring tool for identifying pediatric patients with eosinophilic esophagitis and correlating symptoms with inflammation. Ann Allergy Asthma Immunol. 2009 Nov; 103(5):401-6. Aceves SS, Newbury RO, Dohil MA, Bastian JF, Dohil R. PMID: 19927538.
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    89. Relationships between eosinophilic inflammation, tissue remodeling, and fibrosis in eosinophilic esophagitis. Immunol Allergy Clin North Am. 2009 Feb; 29(1):197-211, xiii-xiv. Aceves SS, Ackerman SJ. PMID: 19141355.
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    90. Airway fibrosis and angiogenesis due to eosinophil trafficking in chronic asthma. Curr Mol Med. 2008 Aug; 8(5):350-8. Aceves SS, Broide DH. PMID: 18691061.
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    91. Integrated approach to treatment of children and adults with eosinophilic esophagitis. Gastrointest Endosc Clin N Am. 2008 Jan; 18(1):195-217; xi. Aceves SS, Furuta GT, Spechler SJ. PMID: 18061112.
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    92. Oral viscous budesonide: a potential new therapy for eosinophilic esophagitis in children. Am J Gastroenterol. 2007 Oct; 102(10):2271-9; quiz 2280. Aceves SS, Bastian JF, Newbury RO, Dohil R. PMID: 17581266.
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    93. Distinguishing eosinophilic esophagitis in pediatric patients: clinical, endoscopic, and histologic features of an emerging disorder. J Clin Gastroenterol. 2007 Mar; 41(3):252-6. Aceves SS, Newbury RO, Dohil R, Schwimmer J, Bastian JF. PMID: 17426462.
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    94. Esophageal remodeling in pediatric eosinophilic esophagitis. J Allergy Clin Immunol. 2007 Jan; 119(1):206-12. Aceves SS, Newbury RO, Dohil R, Bastian JF, Broide DH. PMID: 17208603.
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    95. Eosinophilic disorders in children. Curr Allergy Asthma Rep. 2006 Nov; 6(6):475-82. Wagelie-Steffen A, Aceves SS. PMID: 17026874.
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    96. A randomized, double-blind, placebo-controlled trial of fluticasone propionate for pediatric eosinophilic esophagitis. Gastroenterology. 2006 Nov; 131(5):1381-91. Konikoff MR, Noel RJ, Blanchard C, Kirby C, Jameson SC, Buckmeier BK, Akers R, Cohen MB, Collins MH, Assa'ad AH, Aceves SS, Putnam PE, Rothenberg ME. PMID: 17101314.
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    97. Topical viscous budesonide suspension for treatment of eosinophilic esophagitis. J Allergy Clin Immunol. 2005 Sep; 116(3):705-6. Aceves SS, Dohil R, Newbury RO, Bastian JF. PMID: 16159647.
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