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Bruce Zuraw

TitleProfessor In Residence
InstitutionUniversity of California San Diego
DepartmentMedicine
Address9500 Gilman Drive #0732
La Jolla CA 92093
Phone858-822-6597
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    Collapse Biography 
    Collapse Education and Training
    Loyola Stritch School of Medicine, Maywood, ILMD
    Carleton College, Northfield, MN,BA1972Biology

    Collapse Overview 
    Collapse Overview
    Dr. Zuraw is the Director of the US HAEA Angioedema Center at UC San Diego. Dr. Zuraw specializes in all types of non-histaminergic angioedemas.

    Research Interests
    - Allergic inflammation in humans with particular attention to hereditary angioedema
    - The mechanism of action of glucocorticoids


    Collapse Research 
    Collapse Research Activities and Funding
    Hereditary Angioedema(HAE)Conference
    NIH/NIAID R13AI110081Jan 8, 2014 - Dec 31, 2014
    Role: Principal Investigator
    Dual role of the bradykinin B2 receptor during inflammation
    VA I01BX000154Oct 1, 2010 - Sep 30, 2014
    Role: Principal Investigator
    Airway inflammation and airway remodeling
    NIH/NIAID U19AI070535Jul 1, 2006 - Aug 31, 2021
    Role: Co-Investigator
    GILZ Controls TLR-Induced NF-kB Activity In Acute Asthma
    NIH/NIAID R01AI068086Jul 1, 2005 - Mar 31, 2010
    Role: Principal Investigator
    INITIATION AND PROPAGATION OF ASTHMATIC INFLAMMATION
    NIH/NIAID P01AI050498Sep 10, 2001 - Jun 30, 2007
    Role: Principal Investigator
    RHINOVIRUS MEDIATED TRANSCRIPTION IN AIRWAY INFLAMMATION
    NIH/NHLBI R01HL061003Jul 10, 1998 - Jun 30, 2004
    Role: Principal Investigator
    SIGNALING IN ALLERGIC INFLAMMATION
    NIH U19AI042244Sep 30, 1997 - Oct 15, 2001
    Role: Co-Investigator
    DISEASE VARIABLES IN HEREDITARY ANGIOEDEMA
    NIH/NIAID R01AI036220Mar 1, 1996 - Feb 28, 2002
    Role: Principal Investigator
    REGULATION OF C1 INHIBITOR SYNTHESIS AND CATABOLISM
    NIH/NHLBI R29HL039773Apr 1, 1988 - Mar 31, 1994
    Role: Principal Investigator
    GENERAL CLINICAL RESEARCH CENTER
    NIH M01RR000833Dec 1, 1977 - Sep 30, 2005
    Role: Co-Investigator
    General Clinical Research Center
    NIH/NCRR M01RR000827Mar 1, 1974 - Nov 30, 2010
    Role: Co-Investigator

    Collapse ORNG Applications 
    Collapse Clinical Trials
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Pawaskar D, Tortorici MA, Zuraw B, Craig T, Cicardi M, Longhurst H, Li HH, Lumry WR, Martinez-Saguer I, Jacobs J, Bernstein JA, Riedl MA, Katelaris CH, Keith PK, Feussner A, Sidhu J. Population pharmacokinetics of subcutaneous C1-inhibitor for prevention of attacks in patients with hereditary angioedema. Clin Exp Allergy. 2018 Jul 12. PMID: 29998524.
      View in: PubMed
    2. Cicardi M, Zuraw BL. Angioedema Due to Bradykinin Dysregulation. J Allergy Clin Immunol Pract. 2018 Jul - Aug; 6(4):1132-1141. PMID: 30033914.
      View in: PubMed
    3. Lara-Marquez ML, Christiansen SC, Riedl MA, Herschbach J, Zuraw BL. Threshold-Stimulated Kallikrein Activity Distinguishes Bradykinin- From Histamine-Mediated Angioedema. Clin Exp Allergy. 2018 Jun 29. PMID: 29957871.
      View in: PubMed
    4. Banerji A, Li Y, Busse P, Riedl MA, Holtzman NS, Li HH, Davis-Lorton M, Bernstein JA, Frank M, Castaldo AJ, Long J, Zuraw B, Lumry W, Christiansen S. Hereditary angioedema from the patient's perspective: A follow-up patient survey. Allergy Asthma Proc. 2018 May 01; 39(3):212-223. PMID: 29669666.
      View in: PubMed
    5. Chen M, Kim A, Zuraw B, Doherty TA, Christiansen S. Mast cell disorders: Protean manifestations and treatment responses. Ann Allergy Asthma Immunol. 2018 Mar 28. PMID: 29604336.
      View in: PubMed
    6. Zuraw BL. Hereditary angioedema with normal C1 inhibitor: Four types and counting. J Allergy Clin Immunol. 2018 Mar; 141(3):884-885. PMID: 29410040.
      View in: PubMed
    7. Lumry WR, Craig T, Zuraw B, Longhurst H, Baker J, Li HH, Bernstein JA, Anderson J, Riedl MA, Manning ME, Keith PK, Levy DS, Caballero T, Banerji A, Gower RG, Farkas H, Lawo JP, Pragst I, Machnig T, Watson DJ. Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema. J Allergy Clin Immunol Pract. 2018 Jan 31. PMID: 29391286.
      View in: PubMed
    8. Zhang Y, Tortorici MA, Pawaskar D, Pragst I, Machnig T, Hutmacher M, Zuraw B, Cicardi M, Craig T, Longhurst H, Sidhu J. Exposure-Response Model of Subcutaneous C1-Inhibitor Concentrate to Estimate the Risk of Attacks in Patients With Hereditary Angioedema. CPT Pharmacometrics Syst Pharmacol. 2018 Mar; 7(3):158-165. PMID: 29316335.
      View in: PubMed
    9. Christiansen SC, Zuraw BL. Laboratory Approaches for Assessing Contact System Activation. Immunol Allergy Clin North Am. 2017 08; 37(3):527-539. PMID: 28687107.
      View in: PubMed
    10. Longhurst H, Cicardi M, Craig T, Bork K, Grattan C, Baker J, Li HH, Reshef A, Bonner J, Bernstein JA, Anderson J, Lumry WR, Farkas H, Katelaris CH, Sussman GL, Jacobs J, Riedl M, Manning ME, Hebert J, Keith PK, Kivity S, Neri S, Levy DS, Baeza ML, Nathan R, Schwartz LB, Caballero T, Yang W, Crisan I, Hernandez MD, Hussain I, Tarzi M, Ritchie B, Králícková P, Guilarte M, Rehman SM, Banerji A, Gower RG, Bensen-Kennedy D, Edelman J, Feuersenger H, Lawo JP, Machnig T, Pawaskar D, Pragst I, Zuraw BL. Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor. N Engl J Med. 2017 03 23; 376(12):1131-1140. PMID: 28328347.
      View in: PubMed
    11. Tse KY, Zuraw BL, Chen Q, Christiansen SC. Anabolic androgen use in the management of hereditary angioedema: Not so cheap after all. Ann Allergy Asthma Immunol. 2017 04; 118(4):456-460.e1. PMID: 28283277.
      View in: PubMed
    12. Eastman JJ, Cavagnero KJ, Deconde AS, Kim AS, Karta MR, Broide DH, Zuraw BL, White AA, Christiansen SC, Doherty TA. Group 2 innate lymphoid cells are recruited to the nasal mucosa in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2017 Jul; 140(1):101-108.e3. PMID: 28279492.
      View in: PubMed
    13. Otani IM, Lumry WR, Hurwitz S, Li HH, Craig TJ, Holtzman NS, Iandoli MI, Tucker J, Riedl MA, Zuraw BL, Banerji A. Subcutaneous Icatibant for the Treatment of Hereditary Angioedema Attacks: Comparison of Home Self-Administration with Administration at a Medical Facility. J Allergy Clin Immunol Pract. 2017 Mar - Apr; 5(2):442-447.e1. PMID: 27818136.
      View in: PubMed
    14. Frank MM, Zuraw B, Banerji A, Bernstein JA, Craig T, Busse P, Christiansen S, Davis-Lorton M, Li HH, Lumry WR, Riedl M. Management of Children With Hereditary Angioedema Due to C1 Inhibitor Deficiency. Pediatrics. 2016 Nov; 138(5). PMID: 27940765.
      View in: PubMed
    15. Zuraw BL, Christiansen SC. HAE Pathophysiology and Underlying Mechanisms. Clin Rev Allergy Immunol. 2016 Oct; 51(2):216-29. PMID: 27459852.
      View in: PubMed
    16. Otani IM, Christiansen SC, Busse P, Camargo CA, Zuraw BL, Riedl MA, Banerji A. Emergency Department Management of Hereditary Angioedema Attacks: Patient Perspectives. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):128-134.e4. PMID: 27665386.
      View in: PubMed
    17. Zuraw BL, Davis DK, Castaldo AJ, Christiansen SC. Tolerability and Effectiveness of 17-a-Alkylated Androgen Therapy for Hereditary Angioedema: A Re-examination. J Allergy Clin Immunol Pract. 2016 Sep-Oct; 4(5):948-955.e15. PMID: 27329469.
      View in: PubMed
    18. Hofman ZL, Relan A, Zeerleder S, Drouet C, Zuraw B, Hack CE. Angioedema attacks in patients with hereditary angioedema: Local manifestations of a systemic activation process. J Allergy Clin Immunol. 2016 Aug; 138(2):359-66. PMID: 27246526.
      View in: PubMed
    19. Doshi A, Tse K, Riedl M, Zuraw B, Christiansen S. Cases of acquired C1 inhibitor deficiency treated with rituximab. J Allergy Clin Immunol Pract. 2016 Sep-Oct; 4(5):987-8. PMID: 27130715.
      View in: PubMed
    20. Miller M, Esnault S, Kurten RC, Kelly EA, Beppu A, Das S, Rosenthal P, Ramsdell J, Croft M, Zuraw B, Jarjour N, Hamid Q, Broide DH. Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma. J Allergy Clin Immunol. 2016 Aug; 138(2):596-599.e4. PMID: 27001159; PMCID: PMC4975994 [Available on 08/01/17].
    21. Zuraw BL, Christiansen SC. How we manage persons with hereditary angioedema. Br J Haematol. 2016 06; 173(6):831-43. PMID: 27071490.
      View in: PubMed
    22. Eastman J, Zuraw B. Angioedema due to allergy in a patient with hereditary angioedema: all that glitters is not gold. Ann Allergy Asthma Immunol. 2016 Apr; 116(4):376. PMID: 26916444.
      View in: PubMed
    23. Christiansen SC, Davis DK, Castaldo AJ, Zuraw BL. Pediatric Hereditary Angioedema: Onset, Diagnostic Delay, and Disease Severity. Clin Pediatr (Phila). 2016 Sep; 55(10):935-42. PMID: 26581355.
      View in: PubMed
    24. Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Oct 15; 195(8):3546-56. PMID: 26355153; PMCID: PMC4811198 [Available on 10/15/16].
    25. Christiansen SC, Schatz M, Yang SJ, Ngor E, Chen W, Zuraw BL. Hypertension and Asthma: A Comorbid Relationship. J Allergy Clin Immunol Pract. 2016 Jan-Feb; 4(1):76-81. PMID: 26342745.
      View in: PubMed
    26. Craig T, Pürsün EA, Bork K, Bowen T, Boysen H, Farkas H, Grumach A, Katelaris CH, Lockey R, Longhurst H, Lumry W, Magerl M, Martinez-Saguer I, Ritchie B, Nast A, Pawankar R, Zuraw B, Maurer M. [WAO Guideline for the Management of Hereditary Angioedema]. Arerugi. 2015 Sep; 64(9):1215-41. PMID: 26657910.
      View in: PubMed
    27. Bonner N, Abetz-Webb L, Renault L, Caballero T, Longhurst H, Maurer M, Christiansen S, Zuraw B. Development and content validity testing of a patient-reported outcomes questionnaire for the assessment of hereditary angioedema in observational studies. Health Qual Life Outcomes. 2015 Jul 01; 13:92. PMID: 26129930; PMCID: PMC4487558.
    28. Mehta AK, Duan W, Doerner AM, Traves SL, Broide DH, Proud D, Zuraw BL, Croft M. Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33. J Allergy Clin Immunol. 2016 Jan; 137(1):278-288.e6. PMID: 26100084; PMCID: PMC4684822 [Available on 01/01/17].
    29. Banerji A, Busse P, Christiansen SC, Li H, Lumry W, Davis-Lorton M, Bernstein JA, Frank M, Castaldo A, Long JF, Zuraw BL, Riedl M. Current state of hereditary angioedema management: a patient survey. Allergy Asthma Proc. 2015 May-Jun; 36(3):213-7. PMID: 25976438; PMCID: PMC4405601.
    30. Tse K, Chen L, Tse M, Zuraw B, Christiansen S. Effect of catastrophic wildfires on asthmatic outcomes in obese children: breathing fire. Ann Allergy Asthma Immunol. 2015 Apr; 114(4):308-311.e4. PMID: 25747784; PMCID: PMC4387007.
    31. Christiansen SC, Bygum A, Banerji A, Busse P, Li H, Lumry W, Davis-Lorton M, Bernstein JA, Frank MM, Castaldo A, Long JF, Riedl M, Zuraw BL. Before and after, the impact of available on-demand treatment for HAE. Allergy Asthma Proc. 2015 Mar-Apr; 36(2):145-50. PMID: 25715243.
      View in: PubMed
    32. Betschel S, Badiou J, Binkley K, Hébert J, Kanani A, Keith P, Lacuesta G, Yang B, Aygören-Pürsün E, Bernstein J, Bork K, Caballero T, Cicardi M, Craig T, Farkas H, Longhurst H, Zuraw B, Boysen H, Borici-Mazi R, Bowen T, Dallas K, Dean J, Lang-Robertson K, Laramée B, Leith E, Mace S, McCusker C, Moote B, Poon MC, Ritchie B, Stark D, Sussman G, Waserman S. Canadian hereditary angioedema guideline. Allergy Asthma Clin Immunol. 2014; 10(1):50. PMID: 25352908; PMCID: PMC4210625.
    33. Bernstein JA, Lang DM, Khan DA, Craig T, Dreyfus D, Hsieh F, Sheikh J, Weldon D, Zuraw B, Bernstein DI, Blessing-Moore J, Cox L, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph CR, Schuller DE, Spector SL, Tilles SA, Wallace D. The diagnosis and management of acute and chronic urticaria: 2014 update. J Allergy Clin Immunol. 2014 May; 133(5):1270-7. PMID: 24766875.
      View in: PubMed
    34. Moellman JJ, Bernstein JA, Lindsell C, Banerji A, Busse PJ, Camargo CA, Collins SP, Craig TJ, Lumry WR, Nowak R, Pines JM, Raja AS, Riedl M, Ward MJ, Zuraw BL, Diercks D, Hiestand B, Campbell RL, Schneider S, Sinert R. A consensus parameter for the evaluation and management of angioedema in the emergency department. Acad Emerg Med. 2014 Apr; 21(4):469-84. PMID: 24730413; PMCID: PMC4100605.
    35. Walford HH, Zuraw BL. Current update on cellular and molecular mechanisms of hereditary angioedema. Ann Allergy Asthma Immunol. 2014 May; 112(5):413-8. PMID: 24484972.
      View in: PubMed
    36. Zuraw BL. Immunology and Allergy Clinics of North America. Angioedema. Preface. Immunol Allergy Clin North Am. 2013 Nov; 33(4):xi-xiii. PMID: 24176220.
      View in: PubMed
    37. Zuraw BL, Banerji A, Bernstein JA, Busse PJ, Christiansen SC, Davis-Lorton M, Frank MM, Li HH, Lumry WR, Riedl M. US Hereditary Angioedema Association Medical Advisory Board 2013 recommendations for the management of hereditary angioedema due to C1 inhibitor deficiency. J Allergy Clin Immunol Pract. 2013 Sep-Oct; 1(5):458-67. PMID: 24565617.
      View in: PubMed
    38. Zuraw BL, Christiansen SC. Rare disease partnership: the role of the US HAEA in angioedema care. Immunol Allergy Clin North Am. 2013 Nov; 33(4):545-53. PMID: 24176218.
      View in: PubMed
    39. Zuraw BL, Bernstein JA, Lang DM, Craig T, Dreyfus D, Hsieh F, Khan D, Sheikh J, Weldon D, Bernstein DI, Blessing-Moore J, Cox L, Nicklas RA, Oppenheimer J, Portnoy JM, Randolph CR, Schuller DE, Spector SL, Tilles SA, Wallace D. A focused parameter update: hereditary angioedema, acquired C1 inhibitor deficiency, and angiotensin-converting enzyme inhibitor-associated angioedema. J Allergy Clin Immunol. 2013 Jun; 131(6):1491-3. PMID: 23726531.
      View in: PubMed
    40. Tse K, Zuraw BL. Recognizing and managing hereditary angioedema. Cleve Clin J Med. 2013 May; 80(5):297-308. PMID: 23636922.
      View in: PubMed
    41. Riedl MA, Levy RJ, Suez D, Lockey RF, Baker JW, Relan A, Zuraw BL. Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study. Ann Allergy Asthma Immunol. 2013 Apr; 110(4):295-9. PMID: 23535096.
      View in: PubMed
    42. Lang DM, Aberer W, Bernstein JA, Chng HH, Grumach AS, Hide M, Maurer M, Weber R, Zuraw B. International consensus on hereditary and acquired angioedema. Ann Allergy Asthma Immunol. 2012 Dec; 109(6):395-402. PMID: 23176876.
      View in: PubMed
    43. Craig T, Aygören-Pürsün E, Bork K, Bowen T, Boysen H, Farkas H, Grumach A, Katelaris CH, Lockey R, Longhurst H, Lumry W, Magerl M, Martinez-Saguer I, Ritchie B, Nast A, Pawankar R, Zuraw B, Maurer M. WAO Guideline for the Management of Hereditary Angioedema. World Allergy Organ J. 2012 Dec; 5(12):182-99. PMID: 23282420; PMCID: PMC3651186.
    44. Zuraw BL, Bork K, Binkley KE, Banerji A, Christiansen SC, Castaldo A, Kaplan A, Riedl M, Kirkpatrick C, Magerl M, Drouet C, Cicardi M. Hereditary angioedema with normal C1 inhibitor function: consensus of an international expert panel. Allergy Asthma Proc. 2012 Nov-Dec; 33 Suppl 1:S145-56. PMID: 23394603.
      View in: PubMed
    45. Zuraw BL, Kalfus I. Safety and efficacy of prophylactic nanofiltered C1-inhibitor in hereditary angioedema. Am J Med. 2012 Sep; 125(9):938.e1-7. PMID: 22800873.
      View in: PubMed
    46. Kusuma A, Relan A, Knulst AC, Moldovan D, Zuraw B, Cicardi M, Levy RJ, Nuijens JH, Hack CE. Clinical impact of peripheral attacks in hereditary angioedema patients. Am J Med. 2012 Sep; 125(9):937.e17-24. PMID: 22748405.
      View in: PubMed
    47. Tourangeau LM, Castaldo AJ, Davis DK, Koziol J, Christiansen SC, Zuraw BL. Safety and efficacy of physician-supervised self-managed C1 inhibitor replacement therapy. Int Arch Allergy Immunol. 2012; 157(4):417-24. PMID: 22123229; PMCID: PMC3242706.
    48. Zuraw BL, Christiansen SC. Pathophysiology of hereditary angioedema. Am J Rhinol Allergy. 2011 Nov-Dec; 25(6):373-8. PMID: 22185738.
      View in: PubMed
    49. Christiansen SC, Zuraw BL. Hereditary angioedema: management of laryngeal attacks. Am J Rhinol Allergy. 2011 Nov-Dec; 25(6):379-82. PMID: 22185739.
      View in: PubMed
    50. Tourangeau LM, Zuraw BL. The new era of C1-esterase inhibitor deficiency therapy. Curr Allergy Asthma Rep. 2011 Oct; 11(5):345-51. PMID: 21833753.
      View in: PubMed
    51. Quinto KB, Zuraw BL, Poon KY, Chen W, Schatz M, Christiansen SC. The association of obesity and asthma severity and control in children. J Allergy Clin Immunol. 2011 Nov; 128(5):964-9. PMID: 21820711.
      View in: PubMed
    52. Doherty TA, Soroosh P, Khorram N, Fukuyama S, Rosenthal P, Cho JY, Norris PS, Choi H, Scheu S, Pfeffer K, Zuraw BL, Ware CF, Broide DH, Croft M. The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med. 2011 May; 17(5):596-603. PMID: 21499267; PMCID: PMC3097134.
    53. Zuraw B, Cicardi M, Levy RJ, Nuijens JH, Relan A, Visscher S, Haase G, Kaufman L, Hack CE. Recombinant human C1-inhibitor for the treatment of acute angioedema attacks in patients with hereditary angioedema. J Allergy Clin Immunol. 2010 Oct; 126(4):821-827.e14. PMID: 20920772.
      View in: PubMed
    54. Zuraw BL, Frank MM, Riedl MA. Introduction: New Perspectives in Hereditary Angioedema (HAE): Molecular Mechanisms & Therapeutic Choices: A CME Symposium Presented at the 2009 World Allergy Congress, Buenos Aires, Argentina, December 9, 2009. World Allergy Organ J. 2010 Sep; 3(9 Suppl):S24. PMID: 23282865; PMCID: PMC3666148.
    55. Zuraw BL. Summary and Conclusions: New Perspectives in Hereditary Angioedema: Molecular Mechanisms and Therapeutic Choices: A CME Symposium Presented at the World Allergy Congress, Buenos Aires, Argentina (December 2009). World Allergy Organ J. 2010 Sep; 3(9 Suppl):S39-40. PMID: 23282869; PMCID: PMC3666150.
    56. Zuraw BL. The pathophysiology of hereditary angioedema. World Allergy Organ J. 2010 Sep; 3(9 Suppl):S25-8. PMID: 23282866; PMCID: PMC3666152.
    57. Zuraw BL, Busse PJ, White M, Jacobs J, Lumry W, Baker J, Craig T, Grant JA, Hurewitz D, Bielory L, Cartwright WE, Koleilat M, Ryan W, Schaefer O, Manning M, Patel P, Bernstein JA, Friedman RA, Wilkinson R, Tanner D, Kohler G, Gunther G, Levy R, McClellan J, Redhead J, Guss D, Heyman E, Blumenstein BA, Kalfus I, Frank MM. Nanofiltered C1 inhibitor concentrate for treatment of hereditary angioedema. N Engl J Med. 2010 Aug 05; 363(6):513-22. PMID: 20818886.
      View in: PubMed
    58. Zuraw BL. HAE therapies: past present and future. Allergy Asthma Clin Immunol. 2010 Jul 28; 6(1):23. PMID: 20667126; PMCID: PMC2921104.
    59. Bowen T, Cicardi M, Farkas H, Bork K, Longhurst HJ, Zuraw B, Aygoeren-Pürsün E, Craig T, Binkley K, Hebert J, Ritchie B, Bouillet L, Betschel S, Cogar D, Dean J, Devaraj R, Hamed A, Kamra P, Keith PK, Lacuesta G, Leith E, Lyons H, Mace S, Mako B, Neurath D, Poon MC, Rivard GE, Schellenberg R, Rowan D, Rowe A, Stark D, Sur S, Tsai E, Warrington R, Waserman S, Ameratunga R, Bernstein J, Björkander J, Brosz K, Brosz J, Bygum A, Caballero T, Frank M, Fust G, Harmat G, Kanani A, Kreuz W, Levi M, Li H, Martinez-Saguer I, Moldovan D, Nagy I, Nielsen EW, Nordenfelt P, Reshef A, Rusicke E, Smith-Foltz S, Späth P, Varga L, Xiang ZY. 2010 International consensus algorithm for the diagnosis, therapy and management of hereditary angioedema. Allergy Asthma Clin Immunol. 2010 Jul 28; 6(1):24. PMID: 20667127; PMCID: PMC2921362.
    60. Longhurst HJ, Farkas H, Craig T, Aygören-Pürsün E, Bethune C, Bjorkander J, Bork K, Bouillet L, Boysen H, Bygum A, Caballero T, Cicardi M, Dempster J, Gompels M, Gooi J, Grigoriadou S, Huffer U, Kreuz W, Levi MM, Long J, Martinez-Saguer I, Raguet M, Reshef A, Bowen T, Zuraw B. HAE international home therapy consensus document. Allergy Asthma Clin Immunol. 2010 Jul 28; 6(1):22. PMID: 20667125; PMCID: PMC2922091.
    61. Eddleston J, Lee RU, Doerner AM, Herschbach J, Zuraw BL. Cigarette smoke decreases innate responses of epithelial cells to rhinovirus infection. Am J Respir Cell Mol Biol. 2011 Jan; 44(1):118-26. PMID: 20224072; PMCID: PMC3028255.
    62. Zuraw B, Yasothan U, Kirkpatrick P. Ecallantide. Nat Rev Drug Discov. 2010 Mar; 9(3):189-90. PMID: 20190785.
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    63. Doerner AM, Zuraw BL. TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids. Respir Res. 2009 Oct 27; 10:100. PMID: 19857272; PMCID: PMC2774671.
    64. Zuraw BL, Christiansen SC. Pathogenesis and laboratory diagnosis of hereditary angioedema. Allergy Asthma Proc. 2009 Sep-Oct; 30(5):487-92. PMID: 19843402.
      View in: PubMed
    65. Christiansen SC, Zuraw BL. Update on therapeutic developments for hereditary angioedema. Allergy Asthma Proc. 2009 Sep-Oct; 30(5):500-5. PMID: 19843404.
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    66. Sexton DJ, Chen T, Martik D, Kuzmic P, Kuang G, Chen J, Nixon AE, Zuraw BL, Forteza RM, Abraham WM, Wood CR. Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases. Biochem J. 2009 Aug 13; 422(2):383-92. PMID: 19527222.
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    67. Mukherjee S, Chen LY, Papadimos TJ, Huang S, Zuraw BL, Pan ZK. Lipopolysaccharide-driven Th2 cytokine production in macrophages is regulated by both MyD88 and TRAM. J Biol Chem. 2009 Oct 23; 284(43):29391-8. PMID: 19638630; PMCID: PMC2785571.
    68. Bengtson SH, Eddleston J, Mörgelin M, Zuraw BL, Herwald H. Regulation of kinin B(2) receptors by bradykinin in human lung cells. Biol Chem. 2008 Nov; 389(11):1435-40. PMID: 18783336.
      View in: PubMed
    69. Zuraw BL. Clinical practice. Hereditary angioedema. N Engl J Med. 2008 Sep 04; 359(10):1027-36. PMID: 18768946.
      View in: PubMed
    70. Christiansen SC, Eddleston J, Bengtson SH, Jenkins GR, Sarnoff RB, Turner RB, Gwaltney JM, Zuraw BL. Experimental rhinovirus infection increases human tissue kallikrein activation in allergic subjects. Int Arch Allergy Immunol. 2008; 147(4):299-304. PMID: 18617749.
      View in: PubMed
    71. Kiemer AK, Senaratne RH, Hoppstädter J, Diesel B, Riley LW, Tabeta K, Bauer S, Beutler B, Zuraw BL. Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. J Innate Immun. 2009; 1(1):29-45. PMID: 20375564.
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    72. Zuraw BL, Christiansen SC. New promise and hope for treating hereditary angioedema. Expert Opin Investig Drugs. 2008 May; 17(5):697-706. PMID: 18447596.
      View in: PubMed
    73. Zuraw BL. Hereditary angiodema: a current state-of-the-art review, IV: short- and long-term treatment of hereditary angioedema: out with the old and in with the new? Ann Allergy Asthma Immunol. 2008 Jan; 100(1 Suppl 2):S13-8. PMID: 18220147.
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