Bruce Zuraw

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Biography 
    Collapse Education and Training
    Loyola Stritch School of Medicine, Maywood, ILMD
    Carleton College, Northfield, MN,BA1972Biology

    Collapse Overview 
    Collapse Overview
    Dr. Zuraw is the Director of the US HAEA Angioedema Center at UC San Diego. Dr. Zuraw specializes in all types of non-histaminergic angioedemas.

    Research Interests
    - Allergic inflammation in humans with particular attention to hereditary angioedema
    - The mechanism of action of glucocorticoids

    Collapse Research 
    Collapse Research Activities and Funding
    Mechanisms Underlying the Dominant Negative Phenotype in Hereditary Angioedema
    NIH I01BX004240Oct 1, 2019 - Sep 30, 2023
    Role: Principal Investigator
    Hereditary Angioedema(HAE)Conference
    NIH R13AI110081Jan 8, 2014 - Dec 31, 2014
    Role: Principal Investigator
    Dual role of the bradykinin B2 receptor during inflammation
    NIH I01BX000154Oct 1, 2010 - Sep 30, 2014
    Role: Principal Investigator
    Airway inflammation and airway remodeling
    NIH U19AI070535Jul 1, 2006 - Aug 31, 2021
    Role: Co-Investigator
    GILZ Controls TLR-Induced NF-kB Activity In Acute Asthma
    NIH R01AI068086Jul 1, 2005 - Mar 31, 2010
    Role: Principal Investigator
    INITIATION AND PROPAGATION OF ASTHMATIC INFLAMMATION
    NIH P01AI050498Sep 10, 2001 - Jun 30, 2007
    Role: Principal Investigator
    RHINOVIRUS MEDIATED TRANSCRIPTION IN AIRWAY INFLAMMATION
    NIH R01HL061003Jul 10, 1998 - Jun 30, 2004
    Role: Principal Investigator
    SIGNALING IN ALLERGIC INFLAMMATION
    NIH U19AI042244Sep 30, 1997 - Oct 15, 2001
    Role: Co-Investigator
    General Clinical Research Center
    NIH M01RR000827Jan 27, 1997 - Nov 30, 2010
    Role: Co-Investigator
    DISEASE VARIABLES IN HEREDITARY ANGIOEDEMA
    NIH R01AI036220Mar 1, 1996 - Feb 28, 2002
    Role: Principal Investigator
    REGULATION OF C1 INHIBITOR SYNTHESIS AND CATABOLISM
    NIH R29HL039773Apr 1, 1988 - Mar 31, 1994
    Role: Principal Investigator
    GENERAL CLINICAL RESEARCH CENTER
    NIH M01RR000833Dec 1, 1977 - Sep 30, 2005
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Consensus on treatment goals in hereditary angioedema: a global Delphi initiative. J Allergy Clin Immunol. 2021 May 25. Maurer M, Aygören-Pürsün E, Banerji A, Bernstein JA, Boysen HB, Busse PJ, Bygum A, Caballero T, Castaldo AJ, Christiansen SC, Craig T, Farkas H, Grumach AS, Hide M, Katelaris CH, Li HH, Longhurst H, Lumry WR, Magerl M, Martinez-Saguer I, Riedl MA, Zhi Y, Zuraw B. PMID: 34048855.
      View in: PubMed   Mentions:    Fields:    
    2. Randomized Trial of the Efficacy and Safety of Berotralstat (BCX7353) as an Oral Prophylactic Therapy for Hereditary Angioedema: Results of APeX-2 Through 48 Weeks (Part 2). J Allergy Clin Immunol Pract. 2021 Apr 15. Wedner HJ, Aygören-Pürsün E, Bernstein J, Craig T, Gower R, Jacobs JS, Johnston DT, Lumry W, Zuraw BL, Best JM, Iocca HA, Murray SC, Desai B, Nagy E, Sheridan WP, Kiani-Alikhan S. PMID: 33866032.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    3. The Expanding Spectrum of Mutations in Hereditary Angioedema. J Allergy Clin Immunol Pract. 2021 Jun; 9(6):2229-2234. Veronez CL, Csuka D, Sheikh FR, Zuraw BL, Farkas H, Bork K. PMID: 33746090.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    4. Long-term health-related quality of life in patients treated with subcutaneous C1-inhibitor replacement therapy for the prevention of hereditary angioedema attacks: findings from the COMPACT open-label extension study. Orphanet J Rare Dis. 2021 02 15; 16(1):86. Lumry WR, Zuraw B, Cicardi M, Craig T, Anderson J, Banerji A, Bernstein JA, Caballero T, Farkas H, Gower RG, Keith PK, Levy DS, Li HH, Magerl M, Manning M, Riedl MA, Lawo JP, Prusty S, Machnig T, Longhurst H, the COMPACT Investigators . PMID: 33588897.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    5. Assessing the cost and quality-of-life impact of on-demand-only medications for adults with hereditary angioedema. Allergy Asthma Proc. 2021 03 13; 42(2):108-117. Castaldo AJ, Jervelund C, Corcoran D, Boysen HB, Christiansen SC, Zuraw BL. PMID: 33581742.
      View in: PubMed   Mentions: 1     Fields:    
    6. Intranasal ketorolac, diagnosis, and desensitization for aspirin-exacerbated respiratory disease. Ann Allergy Asthma Immunol. 2021 Jun; 126(6):674-680. Nguyen A, Zuraw BL, Wu C, Kim A, Christiansen SC. PMID: 33476718.
      View in: PubMed   Mentions:    Fields:    
    7. Hereditary angioedema: On-demand treatment of angioedema attacks. Allergy Asthma Proc. 2020 11 01; 41(Suppl 1):S26-S29. Christiansen SC, Zuraw BL. PMID: 33109322.
      View in: PubMed   Mentions: 2     Fields:    
    8. Oral once-daily berotralstat for the prevention of hereditary angioedema attacks: A randomized, double-blind, placebo-controlled phase 3 trial. J Allergy Clin Immunol. 2020 Oct 21. Zuraw B, Lumry WR, Johnston DT, Aygören-Pürsün E, Banerji A, Bernstein JA, Christiansen SC, Jacobs JS, Sitz KV, Gower RG, Gagnon R, Wedner HJ, Kinaciyan T, Hakl R, Hanzlíková J, Anderson JT, McNeil DL, Fritz SB, Yang WH, Tachdjian R, Busse PJ, Craig TJ, Li HH, Farkas H, Best JM, Clemons D, Cornpropst M, Dobo SM, Iocca HA, Kargl D, Nagy E, Murray SC, Collis P, Sheridan WP, Maurer M, Riedl MA. PMID: 33098856.
      View in: PubMed   Mentions: 8     Fields:    
    9. US HAEA Medical Advisory Board 2020 Guidelines for the Management of Hereditary Angioedema. J Allergy Clin Immunol Pract. 2021 01; 9(1):132-150.e3. Busse PJ, Christiansen SC, Riedl MA, Banerji A, Bernstein JA, Castaldo AJ, Craig T, Davis-Lorton M, Frank MM, Li HH, Lumry WR, Zuraw BL. PMID: 32898710.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    10. What is in your pantry? Entomologic anaphylaxis. Allergy Asthma Proc. 2020 07 01; 41(4):290-295. Galant-Swafford J, Zuraw BL, Herschbach J, Mahata M, Mockford EL, Christiansen SC. PMID: 32605699.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsPHPublic Health
    11. Association Between Self-Reported Dental Hygiene Practices and Dental Procedure-Related Recurrent Angioedema Attacks in HAE Subjects: A Multicenter Survey. J Allergy Clin Immunol Pract. 2020 10; 8(9):3162-3169.e5. Singh U, Lumry WR, Busse P, Wedner HJ, Banerji A, Craig TJ, Li HH, Tachdjian R, Jacobs JS, Riedl MA, Davis-Lorton M, Christiansen SC, Zuraw BL, Bernstein JA. PMID: 32534150.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    12. Correction to: The International/Canadian Hereditary Angioedema Guideline. Allergy Asthma Clin Immunol. 2020; 16:33. Betschel S, Badiou J, Binkley K, Borici-Mazi R, Hébert J, Kanani A, Keith P, Lacuesta G, Waserman S, Yang B, Aygören-Pürsün E, Bernstein J, Bork K, Caballero T, Cicardi M, Craig T, Farkas H, Grumach A, Katelaris C, Longhurst H, Riedl M, Zuraw B, Berger M, Boursiquot JN, Boysen H, Castaldo A, Chapdelaine H, Connors L, Fu L, Goodyear D, Haynes A, Kamra P, Kim H, Lang-Robertson K, Leith E, McCusker C, Moote B, O'Keefe A, Othman I, Poon MC, Ritchie B, St-Pierre C, Stark D, Tsai E. PMID: 32399057.
      View in: PubMed   Mentions:
    13. Contact system activation during erythema marginatum in hereditary angioedema. Ann Allergy Asthma Immunol. 2020 04; 124(4):394-395.e1. Nguyen A, Zuraw BL, Christiansen SC. PMID: 31981614.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    14. Treatment of Hypertension in Patients with Asthma. Reply. N Engl J Med. 2019 12 05; 381(23):2279. Christiansen SC, Zuraw BL. PMID: 31801005.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    15. The International/Canadian Hereditary Angioedema Guideline. Allergy Asthma Clin Immunol. 2019; 15:72. Betschel S, Badiou J, Binkley K, Borici-Mazi R, Hébert J, Kanani A, Keith P, Lacuesta G, Waserman S, Yang B, Aygören-Pürsün E, Bernstein J, Bork K, Caballero T, Cicardi M, Craig T, Farkas H, Grumach A, Katelaris C, Longhurst H, Riedl M, Zuraw B, Berger M, Boursiquot JN, Boysen H, Castaldo A, Chapdelaine H, Connors L, Fu L, Goodyear D, Haynes A, Kamra P, Kim H, Lang-Robertson K, Leith E, McCusker C, Moote B, O'Keefe A, Othman I, Poon MC, Ritchie B, St-Pierre C, Stark D, Tsai E. PMID: 31788005.
      View in: PubMed   Mentions:
    16. Treatment of Hypertension in Patients with Asthma. N Engl J Med. 2019 09 12; 381(11):1046-1057. Christiansen SC, Zuraw BL. PMID: 31509675.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimals
    17. Subcutaneous C1 inhibitor for prevention of attacks of hereditary angioedema: additional outcomes and subgroup analysis of a placebo-controlled randomized study. Allergy Asthma Clin Immunol. 2019; 15:49. Li HH, Zuraw B, Longhurst HJ, Cicardi M, Bork K, Baker J, Lumry W, Bernstein J, Manning M, Levy D, Riedl MA, Feuersenger H, Prusty S, Pragst I, Machnig T, Craig T, COMPACT Investigators . PMID: 31485239.
      View in: PubMed   Mentions:
    18. Long-Term Outcomes with Subcutaneous C1-Inhibitor Replacement Therapy for Prevention of Hereditary Angioedema Attacks. J Allergy Clin Immunol Pract. 2019 Jul - Aug; 7(6):1793-1802.e2. Craig T, Zuraw B, Longhurst H, Cicardi M, Bork K, Grattan C, Katelaris C, Sussman G, Keith PK, Yang W, Hébert J, Hanzlikova J, Staubach-Renz P, Martinez-Saguer I, Magerl M, Aygören-Pürsün E, Farkas H, Reshef A, Kivity S, Neri S, Crisan I, Caballero T, Baeza ML, Hernandez MD, Li H, Lumry W, Bernstein JA, Hussain I, Anderson J, Schwartz LB, Jacobs J, Manning M, Levy D, Riedl M, Christiansen S, Feuersenger H, Pragst I, Mycroft S, Pawaskar D, Jacobs I, COMPACT Investigators . PMID: 30772477.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansCTClinical Trials
    19. Cost-Effectiveness of Prophylactic Medications for the Treatment of Hereditary Angioedema Due to C1 Inhibitor Deficiency: A Real-World U.S. Perspective. J Manag Care Spec Pharm. 2019 Feb; 25(2):148-151. Zuraw BL. PMID: 30698094.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    20. Treatment effect of switching from intravenous to subcutaneous C1-inhibitor for prevention of hereditary angioedema attacks: COMPACT subgroup findings. J Allergy Clin Immunol Pract. 2019 Jul - Aug; 7(6):2035-2038. Craig T, Lumry W, Cicardi M, Zuraw B, Bernstein JA, Anderson J, Jacobs J, Riedl MA, Manning ME, Banerji A, Gower RG, Caballero T, Farkas H, Feuersenger H, Jacobs I, Machnig T, Longhurst H, COMPACT Investigators . PMID: 30660873.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCTClinical Trials
    21. Development of a health-related quality of life instrument for patients with hereditary angioedema living in the United States. J Allergy Clin Immunol Pract. 2019 May - Jun; 7(5):1679-1683.e7. Busse PJ, Christiansen SC, Birmingham JM, Overbey JR, Banerji A, Otani IM, Lumry W, Goryachkovsky A, Zuraw BL. PMID: 30550806.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    22. Effect of Lanadelumab Compared With Placebo on Prevention of Hereditary Angioedema Attacks: A Randomized Clinical Trial. JAMA. 2018 11 27; 320(20):2108-2121. Banerji A, Riedl MA, Bernstein JA, Cicardi M, Longhurst HJ, Zuraw BL, Busse PJ, Anderson J, Magerl M, Martinez-Saguer I, Davis-Lorton M, Zanichelli A, Li HH, Craig T, Jacobs J, Johnston DT, Shapiro R, Yang WH, Lumry WR, Manning ME, Schwartz LB, Shennak M, Soteres D, Zaragoza-Urdaz RH, Gierer S, Smith AM, Tachdjian R, Wedner HJ, Hebert J, Rehman SM, Staubach P, Schranz J, Baptista J, Nothaft W, Maurer M, HELP Investigators . PMID: 30480729.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansCTClinical Trials
    23. Population pharmacokinetics of subcutaneous C1-inhibitor for prevention of attacks in patients with hereditary angioedema. Clin Exp Allergy. 2018 10; 48(10):1325-1332. Pawaskar D, Tortorici MA, Zuraw B, Craig T, Cicardi M, Longhurst H, Li HH, Lumry WR, Martinez-Saguer I, Jacobs J, Bernstein JA, Riedl MA, Katelaris CH, Keith PK, Feussner A, Sidhu J. PMID: 29998524.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    24. Threshold-stimulated kallikrein activity distinguishes bradykinin- from histamine-mediated angioedema. Clin Exp Allergy. 2018 11; 48(11):1429-1438. Lara-Marquez ML, Christiansen SC, Riedl MA, Herschbach J, Zuraw BL. PMID: 29957871.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    25. Angioedema Due to Bradykinin Dysregulation. J Allergy Clin Immunol Pract. 2018 Jul - Aug; 6(4):1132-1141. Cicardi M, Zuraw BL. PMID: 30033914.
      View in: PubMed   Mentions: 16     Fields:    Translation:Humans
    26. Hereditary angioedema from the patient's perspective: A follow-up patient survey. Allergy Asthma Proc. 2018 May 01; 39(3):212-223. Banerji A, Li Y, Busse P, Riedl MA, Holtzman NS, Li HH, Davis-Lorton M, Bernstein JA, Frank M, Castaldo AJ, Long J, Zuraw B, Lumry W, Christiansen S. PMID: 29669666.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    27. Mast cell disorders: Protean manifestations and treatment responses. Ann Allergy Asthma Immunol. 2018 07; 121(1):128-130. Chen M, Kim A, Zuraw B, Doherty TA, Christiansen S. PMID: 29604336.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    28. Hereditary angioedema with normal C1 inhibitor: Four types and counting. J Allergy Clin Immunol. 2018 03; 141(3):884-885. Zuraw BL. PMID: 29410040.
      View in: PubMed   Mentions: 19     Fields:    Translation:Humans
    29. Health-Related Quality of Life with Subcutaneous C1-Inhibitor for Prevention of Attacks of Hereditary Angioedema. J Allergy Clin Immunol Pract. 2018 Sep - Oct; 6(5):1733-1741.e3. Lumry WR, Craig T, Zuraw B, Longhurst H, Baker J, Li HH, Bernstein JA, Anderson J, Riedl MA, Manning ME, Keith PK, Levy DS, Caballero T, Banerji A, Gower RG, Farkas H, Lawo JP, Pragst I, Machnig T, Watson DJ. PMID: 29391286.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCTClinical Trials
    30. Exposure-Response Model of Subcutaneous C1-Inhibitor Concentrate to Estimate the Risk of Attacks in Patients With Hereditary Angioedema. CPT Pharmacometrics Syst Pharmacol. 2018 03; 7(3):158-165. Zhang Y, Tortorici MA, Pawaskar D, Pragst I, Machnig T, Hutmacher M, Zuraw B, Cicardi M, Craig T, Longhurst H, Sidhu J. PMID: 29316335.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    31. Laboratory Approaches for Assessing Contact System Activation. Immunol Allergy Clin North Am. 2017 08; 37(3):527-539. Christiansen SC, Zuraw BL. PMID: 28687107.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    32. Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor. N Engl J Med. 2017 03 23; 376(12):1131-1140. Longhurst H, Cicardi M, Craig T, Bork K, Grattan C, Baker J, Li HH, Reshef A, Bonner J, Bernstein JA, Anderson J, Lumry WR, Farkas H, Katelaris CH, Sussman GL, Jacobs J, Riedl M, Manning ME, Hebert J, Keith PK, Kivity S, Neri S, Levy DS, Baeza ML, Nathan R, Schwartz LB, Caballero T, Yang W, Crisan I, Hernandez MD, Hussain I, Tarzi M, Ritchie B, Králícková P, Guilarte M, Rehman SM, Banerji A, Gower RG, Bensen-Kennedy D, Edelman J, Feuersenger H, Lawo JP, Machnig T, Pawaskar D, Pragst I, Zuraw BL, COMPACT Investigators . PMID: 28328347.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansCTClinical Trials
    33. Anabolic androgen use in the management of hereditary angioedema: Not so cheap after all. Ann Allergy Asthma Immunol. 2017 04; 118(4):456-460.e1. Tse KY, Zuraw BL, Chen Q, Christiansen SC. PMID: 28283277.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    34. Group 2 innate lymphoid cells are recruited to the nasal mucosa in patients with aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2017 Jul; 140(1):101-108.e3. Eastman JJ, Cavagnero KJ, Deconde AS, Kim AS, Karta MR, Broide DH, Zuraw BL, White AA, Christiansen SC, Doherty TA. PMID: 28279492.
      View in: PubMed   Mentions: 25     Fields:    Translation:HumansCells
    35. Subcutaneous Icatibant for the Treatment of Hereditary Angioedema Attacks: Comparison of Home Self-Administration with Administration at a Medical Facility. J Allergy Clin Immunol Pract. 2017 Mar - Apr; 5(2):442-447.e1. Otani IM, Lumry WR, Hurwitz S, Li HH, Craig TJ, Holtzman NS, Iandoli MI, Tucker J, Riedl MA, Zuraw BL, Banerji A. PMID: 27818136.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    36. Management of Children With Hereditary Angioedema Due to C1 Inhibitor Deficiency. Pediatrics. 2016 11; 138(5). Frank MM, Zuraw B, Banerji A, Bernstein JA, Craig T, Busse P, Christiansen S, Davis-Lorton M, Li HH, Lumry WR, Riedl M, US Hereditary Angioedema Association Medical Advisory Board . PMID: 27940765.
      View in: PubMed   Mentions: 9     Fields:    Translation:Humans
    37. HAE Pathophysiology and Underlying Mechanisms. Clin Rev Allergy Immunol. 2016 Oct; 51(2):216-29. Zuraw BL, Christiansen SC. PMID: 27459852.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    38. Emergency Department Management of Hereditary Angioedema Attacks: Patient Perspectives. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):128-134.e4. Otani IM, Christiansen SC, Busse P, Camargo CA, Zuraw BL, Riedl MA, Banerji A. PMID: 27665386.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    39. Tolerability and Effectiveness of 17-a-Alkylated Androgen Therapy for Hereditary Angioedema: A Re-examination. J Allergy Clin Immunol Pract. 2016 Sep-Oct; 4(5):948-955.e15. Zuraw BL, Davis DK, Castaldo AJ, Christiansen SC. PMID: 27329469.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    40. Angioedema attacks in patients with hereditary angioedema: Local manifestations of a systemic activation process. J Allergy Clin Immunol. 2016 08; 138(2):359-66. Hofman ZL, Relan A, Zeerleder S, Drouet C, Zuraw B, Hack CE. PMID: 27246526.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    41. Cases of acquired C1 inhibitor deficiency treated with rituximab. J Allergy Clin Immunol Pract. 2016 Sep-Oct; 4(5):987-8. Doshi A, Tse K, Riedl M, Zuraw B, Christiansen S. PMID: 27130715.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    42. Segmental allergen challenge increases levels of airway follistatin-like 1 in patients with asthma. J Allergy Clin Immunol. 2016 08; 138(2):596-599.e4. Miller M, Esnault S, Kurten RC, Kelly EA, Beppu A, Das S, Rosenthal P, Ramsdell J, Croft M, Zuraw B, Jarjour N, Hamid Q, Broide DH. PMID: 27001159.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    43. How we manage persons with hereditary angioedema. Br J Haematol. 2016 06; 173(6):831-43. Zuraw BL, Christiansen SC. PMID: 27071490.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    44. Angioedema due to allergy in a patient with hereditary angioedema: all that glitters is not gold. Ann Allergy Asthma Immunol. 2016 Apr; 116(4):376. Eastman J, Zuraw B. PMID: 26916444.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    45. Pediatric Hereditary Angioedema: Onset, Diagnostic Delay, and Disease Severity. Clin Pediatr (Phila). 2016 09; 55(10):935-42. Christiansen SC, Davis DK, Castaldo AJ, Zuraw BL. PMID: 26581355.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    46. Fstl1 Promotes Asthmatic Airway Remodeling by Inducing Oncostatin M. J Immunol. 2015 Oct 15; 195(8):3546-56. Miller M, Beppu A, Rosenthal P, Pham A, Das S, Karta M, Song DJ, Vuong C, Doherty T, Croft M, Zuraw B, Zhang X, Gao X, Aceves S, Chouiali F, Hamid Q, Broide DH. PMID: 26355153.
      View in: PubMed   Mentions: 16     Fields:    Translation:HumansAnimalsCells
    47. Hypertension and Asthma: A Comorbid Relationship. J Allergy Clin Immunol Pract. 2016 Jan-Feb; 4(1):76-81. Christiansen SC, Schatz M, Yang SJ, Ngor E, Chen W, Zuraw BL. PMID: 26342745.
      View in: PubMed   Mentions: 12     Fields:    Translation:Humans
    48. [WAO Guideline for the Management of Hereditary Angioedema]. Arerugi. 2015 Sep; 64(9):1215-41. Craig T, Pürsün EA, Bork K, Bowen T, Boysen H, Farkas H, Grumach A, Katelaris CH, Lockey R, Longhurst H, Lumry W, Magerl M, Martinez-Saguer I, Ritchie B, Nast A, Pawankar R, Zuraw B, Maurer M. PMID: 26657910.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    49. Phase II study results of a replacement therapy for hereditary angioedema with subcutaneous C1-inhibitor concentrate. Allergy. 2015 Oct; 70(10):1319-28. Zuraw BL, Cicardi M, Longhurst HJ, Bernstein JA, Li HH, Magerl M, Martinez-Saguer I, Rehman SM, Staubach P, Feuersenger H, Parasrampuria R, Sidhu J, Edelman J, Craig T. PMID: 26016741.
      View in: PubMed   Mentions: 18     Fields:    Translation:HumansCTClinical Trials
    50. Development and content validity testing of a patient-reported outcomes questionnaire for the assessment of hereditary angioedema in observational studies. Health Qual Life Outcomes. 2015 Jul 01; 13:92. Bonner N, Abetz-Webb L, Renault L, Caballero T, Longhurst H, Maurer M, Christiansen S, Zuraw B, Icatibant Outcome Survey (IOS) International Executive Committee and the Hereditary Angioedema Assoc . PMID: 26129930.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    51. Rhinovirus infection interferes with induction of tolerance to aeroantigens through OX40 ligand, thymic stromal lymphopoietin, and IL-33. J Allergy Clin Immunol. 2016 Jan; 137(1):278-288.e6. Mehta AK, Duan W, Doerner AM, Traves SL, Broide DH, Proud D, Zuraw BL, Croft M. PMID: 26100084.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    52. Current state of hereditary angioedema management: a patient survey. Allergy Asthma Proc. 2015 May-Jun; 36(3):213-7. Banerji A, Busse P, Christiansen SC, Li H, Lumry W, Davis-Lorton M, Bernstein JA, Frank M, Castaldo A, Long JF, Zuraw BL, Riedl M. PMID: 25976438.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    53. Effect of catastrophic wildfires on asthmatic outcomes in obese children: breathing fire. Ann Allergy Asthma Immunol. 2015 Apr; 114(4):308-311.e4. Tse K, Chen L, Tse M, Zuraw B, Christiansen S. PMID: 25747784.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansPHPublic Health
    54. Before and after, the impact of available on-demand treatment for HAE. Allergy Asthma Proc. 2015 Mar-Apr; 36(2):145-50. Christiansen SC, Bygum A, Banerji A, Busse P, Li H, Lumry W, Davis-Lorton M, Bernstein JA, Frank MM, Castaldo A, Long JF, Riedl M, Zuraw BL. PMID: 25715243.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    55. Canadian hereditary angioedema guideline. Allergy Asthma Clin Immunol. 2014; 10(1):50. Betschel S, Badiou J, Binkley K, Hébert J, Kanani A, Keith P, Lacuesta G, Yang B, Aygören-Pürsün E, Bernstein J, Bork K, Caballero T, Cicardi M, Craig T, Farkas H, Longhurst H, Zuraw B, Boysen H, Borici-Mazi R, Bowen T, Dallas K, Dean J, Lang-Robertson K, Laramée B, Leith E, Mace S, McCusker C, Moote B, Poon MC, Ritchie B, Stark D, Sussman G, Waserman S. PMID: 25352908.
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    59. Immunology and Allergy Clinics of North America. Angioedema. Preface. Immunol Allergy Clin North Am. 2013 Nov; 33(4):xi-xiii. Zuraw BL. PMID: 24176220.
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    60. US Hereditary Angioedema Association Medical Advisory Board 2013 recommendations for the management of hereditary angioedema due to C1 inhibitor deficiency. J Allergy Clin Immunol Pract. 2013 Sep-Oct; 1(5):458-67. Zuraw BL, Banerji A, Bernstein JA, Busse PJ, Christiansen SC, Davis-Lorton M, Frank MM, Li HH, Lumry WR, Riedl M, US Hereditary Angioedema Association Medical Advisory Board . PMID: 24565617.
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    63. Recognizing and managing hereditary angioedema. Cleve Clin J Med. 2013 May; 80(5):297-308. Tse K, Zuraw BL. PMID: 23636922.
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    64. Efficacy and safety of recombinant C1 inhibitor for the treatment of hereditary angioedema attacks: a North American open-label study. Ann Allergy Asthma Immunol. 2013 Apr; 110(4):295-9. Riedl MA, Levy RJ, Suez D, Lockey RF, Baker JW, Relan A, Zuraw BL. PMID: 23535096.
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    65. WAO Guideline for the Management of Hereditary Angioedema. World Allergy Organ J. 2012 Dec; 5(12):182-99. Craig T, Aygören-Pürsün E, Bork K, Bowen T, Boysen H, Farkas H, Grumach A, Katelaris CH, Lockey R, Longhurst H, Lumry W, Magerl M, Martinez-Saguer I, Ritchie B, Nast A, Pawankar R, Zuraw B, Maurer M. PMID: 23282420.
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    67. Hereditary angioedema with normal C1 inhibitor function: consensus of an international expert panel. Allergy Asthma Proc. 2012 Nov-Dec; 33 Suppl 1:S145-56. Zuraw BL, Bork K, Binkley KE, Banerji A, Christiansen SC, Castaldo A, Kaplan A, Riedl M, Kirkpatrick C, Magerl M, Drouet C, Cicardi M. PMID: 23394603.
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    68. Safety and efficacy of prophylactic nanofiltered C1-inhibitor in hereditary angioedema. Am J Med. 2012 Sep; 125(9):938.e1-7. Zuraw BL, Kalfus I. PMID: 22800873.
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    70. Safety and efficacy of physician-supervised self-managed C1 inhibitor replacement therapy. Int Arch Allergy Immunol. 2012; 157(4):417-24. Tourangeau LM, Castaldo AJ, Davis DK, Koziol J, Christiansen SC, Zuraw BL. PMID: 22123229.
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    71. Pathophysiology of hereditary angioedema. Am J Rhinol Allergy. 2011 Nov-Dec; 25(6):373-8. Zuraw BL, Christiansen SC. PMID: 22185738.
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    72. Hereditary angioedema: management of laryngeal attacks. Am J Rhinol Allergy. 2011 Nov-Dec; 25(6):379-82. Christiansen SC, Zuraw BL. PMID: 22185739.
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    73. The new era of C1-esterase inhibitor deficiency therapy. Curr Allergy Asthma Rep. 2011 Oct; 11(5):345-51. Tourangeau LM, Zuraw BL. PMID: 21833753.
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    74. Abstracts from the North American Rhinology & Allergy Conference, February 3, 2011, Puerto Rico. Am J Rhinol Allergy. 2011 Sep 01; 25(5):369. Carr WW, Bernstein DI, Hampel FC, Gow JA, Williams JI, Zuraw BL, Chipps BE, Miller TA, Berger WE, Carr WW, Tort MJ. PMID: 29021069.
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    75. The association of obesity and asthma severity and control in children. J Allergy Clin Immunol. 2011 Nov; 128(5):964-9. Quinto KB, Zuraw BL, Poon KY, Chen W, Schatz M, Christiansen SC. PMID: 21820711.
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    76. The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling. Nat Med. 2011 May; 17(5):596-603. Doherty TA, Soroosh P, Khorram N, Fukuyama S, Rosenthal P, Cho JY, Norris PS, Choi H, Scheu S, Pfeffer K, Zuraw BL, Ware CF, Broide DH, Croft M. PMID: 21499267.
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    86. Ecallantide. Nat Rev Drug Discov. 2010 Mar; 9(3):189-90. Zuraw B, Yasothan U, Kirkpatrick P. PMID: 20190785.
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    87. TGF-beta1 induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells is enhanced by IL-1beta but not abrogated by corticosteroids. Respir Res. 2009 Oct 27; 10:100. Doerner AM, Zuraw BL. PMID: 19857272.
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    90. Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases. Biochem J. 2009 Aug 13; 422(2):383-92. Sexton DJ, Chen T, Martik D, Kuzmic P, Kuang G, Chen J, Nixon AE, Zuraw BL, Forteza RM, Abraham WM, Wood CR. PMID: 19527222.
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    91. Lipopolysaccharide-driven Th2 cytokine production in macrophages is regulated by both MyD88 and TRAM. J Biol Chem. 2009 Oct 23; 284(43):29391-8. Mukherjee S, Chen LY, Papadimos TJ, Huang S, Zuraw BL, Pan ZK. PMID: 19638630.
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    92. Regulation of kinin B(2) receptors by bradykinin in human lung cells. Biol Chem. 2008 Nov; 389(11):1435-40. Bengtson SH, Eddleston J, Mörgelin M, Zuraw BL, Herwald H. PMID: 18783336.
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    93. Clinical practice. Hereditary angioedema. N Engl J Med. 2008 Sep 04; 359(10):1027-36. Zuraw BL. PMID: 18768946.
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    94. Experimental rhinovirus infection increases human tissue kallikrein activation in allergic subjects. Int Arch Allergy Immunol. 2008; 147(4):299-304. Christiansen SC, Eddleston J, Bengtson SH, Jenkins GR, Sarnoff RB, Turner RB, Gwaltney JM, Zuraw BL. PMID: 18617749.
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    95. Attenuated activation of macrophage TLR9 by DNA from virulent mycobacteria. J Innate Immun. 2009; 1(1):29-45. Kiemer AK, Senaratne RH, Hoppstädter J, Diesel B, Riley LW, Tabeta K, Bauer S, Beutler B, Zuraw BL. PMID: 20375564.
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    96. New promise and hope for treating hereditary angioedema. Expert Opin Investig Drugs. 2008 May; 17(5):697-706. Zuraw BL, Christiansen SC. PMID: 18447596.
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    97. Hereditary angiodema: a current state-of-the-art review, IV: short- and long-term treatment of hereditary angioedema: out with the old and in with the new? Ann Allergy Asthma Immunol. 2008 Jan; 100(1 Suppl 2):S13-8. Zuraw BL. PMID: 18220147.
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    98. Hereditary angiodema: a current state-of-the-art review, VII: Canadian Hungarian 2007 International Consensus Algorithm for the Diagnosis, Therapy, and Management of Hereditary Angioedema. Ann Allergy Asthma Immunol. 2008 Jan; 100(1 Suppl 2):S30-40. Bowen T, Cicardi M, Bork K, Zuraw B, Frank M, Ritchie B, Farkas H, Varga L, Zingale LC, Binkley K, Wagner E, Adomaitis P, Brosz K, Burnham J, Warrington R, Kalicinsky C, Mace S, McCusker C, Schellenberg R, Celeste L, Hebert J, Valentine K, Poon MC, Serushago B, Neurath D, Yang W, Lacuesta G, Issekutz A, Hamed A, Kamra P, Dean J, Kanani A, Stark D, Rivard GE, Leith E, Tsai E, Waserman S, Keith PK, Page D, Marchesin S, Longhurst HJ, Kreuz W, Rusicke E, Martinez-Saguer I, Aygören-Pürsün E, Harmat G, Füst G, Li H, Bouillet L, Caballero T, Moldovan D, Späth PJ, Smith-Foltz S, Nagy I, Nielsen EW, Bucher C, Nordenfelt P, Xiang ZY. PMID: 18220150.
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    99. Galectin-3 functions as an adhesion molecule to support eosinophil rolling and adhesion under conditions of flow. J Immunol. 2007 Dec 01; 179(11):7800-7. Rao SP, Wang Z, Zuberi RI, Sikora L, Bahaie NS, Zuraw BL, Liu FT, Sriramarao P. PMID: 18025226.
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    102. The anti-inflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells. J Allergy Clin Immunol. 2007 Jan; 119(1):115-22. Eddleston J, Herschbach J, Wagelie-Steffen AL, Christiansen SC, Zuraw BL. PMID: 17208592.
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    103. Kinin receptor expression during Staphylococcus aureus infection. Blood. 2006 Sep 15; 108(6):2055-63. Bengtson SH, Phagoo SB, Norrby-Teglund A, Påhlman L, Mörgelin M, Zuraw BL, Leeb-Lundberg LM, Herwald H. PMID: 16735595.
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    105. International union of pharmacology. XLV. Classification of the kinin receptor family: from molecular mechanisms to pathophysiological consequences. Pharmacol Rev. 2005 Mar; 57(1):27-77. Leeb-Lundberg LM, Marceau F, Müller-Esterl W, Pettibone DJ, Zuraw BL. PMID: 15734727.
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    110. A Rho exchange factor mediates fMet-Leu-Phe-induced NF-kappaB activation in human peripheral blood monocytes. J Biol Chem. 2004 Feb 20; 279(8):7208-12. Chen LY, Zuraw BL, Ye RD, Pan ZK. PMID: 14660653.
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    112. Bradykinin increases the in vivo expression of the CXC chemokine receptors CXCR1 and CXCR2 in patients with allergic rhinitis. J Allergy Clin Immunol. 2003 Jan; 111(1):106-12. Eddleston J, Christiansen SC, Jenkins GR, Koziol JA, Zuraw BL. PMID: 12532104.
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    127. Evaluation of a school-based asthma education program for inner-city children. J Allergy Clin Immunol. 1997 Nov; 100(5):613-7. Christiansen SC, Martin SB, Schleicher NC, Koziol JA, Mathews KP, Zuraw BL. PMID: 9389290.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    128. Urticaria, angioedema, and autoimmunity. Clin Lab Med. 1997 Sep; 17(3):559-69. Zuraw BL. PMID: 9316773.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    129. Analysis of an exon 1 polymorphism of the B2 bradykinin receptor gene and its transcript in normal subjects and patients with C1 inhibitor deficiency. J Allergy Clin Immunol. 1997 Jan; 99(1 Pt 1):134-46. Lung CC, Chan EK, Zuraw BL. PMID: 9003221.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    130. Bradykinin stimulates NF-kappaB activation and interleukin 1beta gene expression in cultured human fibroblasts. J Clin Invest. 1996 Nov 01; 98(9):2042-9. Pan ZK, Zuraw BL, Lung CC, Prossnitz ER, Browning DD, Ye RD. PMID: 8903323.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    131. Exposure and sensitization to environmental allergen of predominantly Hispanic children with asthma in San Diego's inner city. J Allergy Clin Immunol. 1996 Aug; 98(2):288-94. Christiansen SC, Martin SB, Schleicher NC, Koziol JA, Hamilton RG, Zuraw BL. PMID: 8757205.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsPHPublic Health
    132. Exon 1 sequence of the human B2 bradykinin receptor gene and its transcript. Immunopharmacology. 1996 Jun; 33(1-3):90-2. Lung CC, Chan EK, Zuraw BL. PMID: 8856121.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    133. Current prevalence of asthma-related symptoms in San Diego's predominantly Hispanic inner-city children. J Asthma. 1996; 33(1):17-26. Christiansen SC, Martin SB, Schleicher NC, Koziol JA, Mathews KP, Zuraw BL. PMID: 8621367.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    134. Evidence for IgG autoantibodies to galectin-3, a beta-galactoside-binding lectin (Mac-2, epsilon binding protein, or carbohydrate binding protein 35) in human serum. J Clin Immunol. 1995 Nov; 15(6):329-37. Mathews KP, Konstantinov KN, Kuwabara I, Hill PN, Hsu DK, Zuraw BL, Liu FT. PMID: 8576319.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    135. Inhibition of monocyte leukotriene B4 production after aspirin desensitization. J Allergy Clin Immunol. 1995 Aug; 96(2):148-56. Juergens UR, Christiansen SC, Stevenson DD, Zuraw BL. PMID: 7636051.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansCells
    136. Improved method for measuring C1-r-C1-s-(C1 inh)2 complexes by an enzyme-linked immunosorbent assay. J Clin Lab Anal. 1995; 9(3):196-203. Mathews KP, Herschbach JH, Chambers SL, Zuraw BL. PMID: 7602428.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    137. Interleukin-6 and interstitial cystitis. J Urol. 1994 Sep; 152(3):869-73. Lotz M, Villiger P, Hugli T, Koziol J, Zuraw BL. PMID: 8051739.
      View in: PubMed   Mentions: 20     Fields:    Translation:HumansCells
    138. Activation of urinary kallikrein in patients with interstitial cystitis. J Urol. 1994 Sep; 152(3):874-8. Zuraw BL, Sugimoto S, Parsons CL, Hugli T, Lotz M, Koziol J. PMID: 8051740.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    139. Arachidonic acid metabolism in monocytes of aspirin-sensitive asthmatic patients before and after oral aspirin challenge. J Allergy Clin Immunol. 1992 Oct; 90(4 Pt 1):636-45. Juergens UR, Christiansen SC, Stevenson DD, Zuraw BL. PMID: 1328344.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    140. Cold-dependent activation of complement: recognition, assessment, and mechanism. J Clin Immunol. 1992 Sep; 12(5):362-70. Mathews KP, Mentyka RA, Chambers SL, Hugli TE, Herschbach JH, Zuraw BL. PMID: 1430107.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    141. Elevation of tissue kallikrein and kinin in the airways of asthmatic subjects after endobronchial allergen challenge. Am Rev Respir Dis. 1992 Apr; 145(4 Pt 1):900-5. Christiansen SC, Proud D, Sarnoff RB, Juergens U, Cochrane CG, Zuraw BL. PMID: 1554219.
      View in: PubMed   Mentions: 35     Fields:    Translation:Humans
    142. Acute consumption of C1 inhibitor in a patient with acquired C1-inhibitor deficiency syndrome. J Allergy Clin Immunol. 1991 Dec; 88(6):908-18. Zuraw BL, Altman LC. PMID: 1744362.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    143. Regulation of the hepatic synthesis of C1 inhibitor by the hepatocyte stimulating factors interleukin 6 and interferon gamma. J Biol Chem. 1990 Jul 25; 265(21):12664-70. Zuraw BL, Lotz M. PMID: 1695634.
      View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
    144. Inhibition of human bronchial kallikrein in asthma. Am Rev Respir Dis. 1989 May; 139(5):1125-31. Christiansen SC, Zuraw BL, Proud D, Cochrane CG. PMID: 2785358.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    145. High-molecular-weight kininogen is cleaved in active erythema multiforme. J Allergy Clin Immunol. 1989 Apr; 83(4):802-10. Lang DM, Sugimoto SL, Curd JG, Christiansen SC, Zuraw BL. PMID: 2708741.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    146. Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis. J Clin Invest. 1989 Feb; 83(2):585-92. Guerne PA, Zuraw BL, Vaughan JH, Carson DA, Lotz M. PMID: 2464001.
      View in: PubMed   Mentions: 113     Fields:    Translation:HumansCells
    147. Detection and quantitation of cleaved and uncleaved high molecular weight kininogen in plasma by ligand blotting with radiolabeled plasma prekallikrein or factor XI. Thromb Haemost. 1988 Apr 08; 59(2):151-61. Lämmle B, Zuraw BL, Heeb MJ, Schwarz HP, Berrettini M, Curd JG, Griffin JH. PMID: 3388291.
      View in: PubMed   Mentions: 8     Fields:    Translation:Humans
    148. Interferon-gamma is a major regulator of C1-inhibitor synthesis by human blood monocytes. J Immunol. 1987 Nov 15; 139(10):3382-7. Lotz M, Zuraw BL. PMID: 3119706.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    149. The value of rocket immunoelectrophoresis for C4 activation in the evaluation of patients with angioedema or C1-inhibitor deficiency. J Allergy Clin Immunol. 1986 Dec; 78(6):1115-20. Zuraw BL, Sugimoto S, Curd JG. PMID: 3782676.
      View in: PubMed   Mentions: 2     Fields:    Translation:Humans
    150. Demonstration of modified inactive first component of complement (C1) inhibitor in the plasmas of C1 inhibitor-deficient patients. J Clin Invest. 1986 Aug; 78(2):567-75. Zuraw BL, Curd JG. PMID: 3734104.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
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