Loading...

Tomoko Hayashi

Title(s)Project Scientist, Cancer Center
SchoolHealth Sciences
Address9500 Gilman Drive #0695
La Jolla CA 92093
Phone858-822-0253
vCardDownload vCard

    Collapse Overview 

    Collapse ORNG Applications 
    Collapse Websites

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. A Novel Synthetic Dual Agonistic Liposomal TLR4/7 Adjuvant Promotes Broad Immune Responses in an Influenza Vaccine With Minimal Reactogenicity. Front Immunol. 2020; 11:1207. Sato-Kaneko F, Yao S, Lao FS, Shpigelman J, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Chu PJ, Burkhart D, Schoener R, Matsutani T, Carson DA, Corr M, Hayashi T. PMID: 32636840.
      View in: PubMed   Mentions:    Fields:    
    2. Structure-Activity Relationship Studies To Identify Affinity Probes in Bis-aryl Sulfonamides That Prolong Immune Stimuli. J Med Chem. 2019 11 14; 62(21):9521-9540. Chan M, Lao FS, Chu PJ, Shpigelman J, Yao S, Nan J, Sato-Kaneko F, Li V, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. PMID: 31603681.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    3. Irreversible Electroporation Combined with Checkpoint Blockade and TLR7 Stimulation Induces Antitumor Immunity in a Murine Pancreatic Cancer Model. Cancer Immunol Res. 2019 10; 7(10):1714-1726. Narayanan JSS, Ray P, Hayashi T, Whisenant TC, Vicente D, Carson DA, Miller AM, Schoenberger SP, White RR. PMID: 31409607.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    4. Conjugation of a Small-Molecule TLR7 Agonist to Silica Nanoshells Enhances Adjuvant Activity. ACS Appl Mater Interfaces. 2019 Jul 31; 11(30):26637-26647. Huang CH, Mendez N, Echeagaray OH, Weeks J, Wang J, Vallez CN, Gude N, Trogler WC, Carson DA, Hayashi T, Kummel AC. PMID: 31276378.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    5. Recent Advances and Perspectives in Small-molecule TLR Ligands and Their Modulators. ACS Med Chem Lett. 2018 Dec 13; 9(12):1156-1159. Shukla NM, Chan M, Hayashi T, Carson DA, Cottam HB. PMID: 30613317.
      View in: PubMed   Mentions:
    6. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy. Biomed Res Int. 2018; 2018:8091283. Sato-Kaneko F, Wang X, Yao S, Hosoya T, Lao FS, Messer K, Pu M, Shukla NM, Cottam HB, Chan M, Carson DA, Corr M, Hayashi T. PMID: 30406141.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    7. Induction of oligoclonal CD8 T cell responses against pulmonary metastatic cancer by a phospholipid-conjugated TLR7 agonist. Proc Natl Acad Sci U S A. 2018 07 17; 115(29):E6836-E6844. Hosoya T, Sato-Kaneko F, Ahmadi A, Yao S, Lao F, Kitaura K, Matsutani T, Carson DA, Hayashi T. PMID: 29967183.
      View in: PubMed   Mentions: 1     Fields:    Translation:AnimalsCells
    8. Identification of Compounds That Prolong Type I Interferon Signaling as Potential Vaccine Adjuvants. SLAS Discov. 2018 10; 23(9):960-973. Shukla NM, Arimoto KI, Yao S, Fan JB, Zhang Y, Sato-Kaneko F, Lao FS, Hosoya T, Messer K, Pu M, Cottam HB, Carson DA, Hayashi T, Zhang DE, Corr M. PMID: 29751735.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    9. Structure-Activity Relationship Studies of Pyrimido[5,4-b]indoles as Selective Toll-Like Receptor 4 Ligands. J Med Chem. 2017 11 22; 60(22):9142-9161. Chan M, Kakitsubata Y, Hayashi T, Ahmadi A, Yao S, Shukla NM, Oyama SY, Baba A, Nguyen B, Corr M, Suda Y, Carson DA, Cottam HB, Wakao M. PMID: 29049886.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimals
    10. Combination immunotherapy with TLR agonists and checkpoint inhibitors suppresses head and neck cancer. JCI Insight. 2017 09 21; 2(18). Sato-Kaneko F, Yao S, Ahmadi A, Zhang SS, Hosoya T, Kaneda MM, Varner JA, Pu M, Messer KS, Guiducci C, Coffman RL, Kitaura K, Matsutani T, Suzuki R, Carson DA, Hayashi T, Cohen EE. PMID: 28931759.
      View in: PubMed   Mentions: 34     Fields:    Translation:HumansAnimalsCells
    11. Identification of Biologically Active Pyrimido[5,4-b]indoles That Prolong NF-?B Activation without Intrinsic Activity. ACS Comb Sci. 2017 08 14; 19(8):533-543. Chan M, Ahmadi A, Yao S, Sato-Kaneko F, Messer K, Pu M, Nguyen B, Hayashi T, Corr M, Carson DA, Cottam HB, Shukla NM. PMID: 28657707.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity. Cell. 2016 Dec 01; 167(6):1525-1539.e17. Moroishi T, Hayashi T, Pan WW, Fujita Y, Holt MV, Qin J, Carson DA, Guan KL. PMID: 27912060.
      View in: PubMed   Mentions: 69     Fields:    Translation:AnimalsCells
    13. Enhancement of the Immunostimulatory Activity of a TLR7 Ligand by Conjugation to Polysaccharides. Bioconjug Chem. 2015 Aug 19; 26(8):1713-23. Shinchi H, Crain B, Yao S, Chan M, Zhang SS, Ahmadiiveli A, Suda Y, Hayashi T, Cottam HB, Carson DA. PMID: 26193334.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    14. Induction of Tolerogenic Dendritic Cells by a PEGylated TLR7 Ligand for Treatment of Type 1 Diabetes. PLoS One. 2015; 10(6):e0129867. Hayashi T, Yao S, Crain B, Promessi VJ, Shyu L, Sheng C, Kang M, Cottam HB, Carson DA, Corr M. PMID: 26076454.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Discovery of substituted 4-aminoquinazolines as selective Toll-like receptor 4 ligands. Bioorg Med Chem Lett. 2014 Nov 01; 24(21):4931-8. Nour A, Hayashi T, Chan M, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Ahmadiiveli A, Messer K, Pu M, Corr M, Carson DA, Cottam HB. PMID: 25288184.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    16. Novel synthetic toll-like receptor 4/MD2 ligands attenuate sterile inflammation. J Pharmacol Exp Ther. 2014 Aug; 350(2):330-40. Hayashi T, Crain B, Yao S, Caneda CD, Cottam HB, Chan M, Corr M, Carson DA. PMID: 24893985.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    17. Innate immune protection against infectious diseases by pulmonary administration of a phospholipid-conjugated TLR7 ligand. J Innate Immun. 2014; 6(3):315-24. Wu CC, Crain B, Yao S, Sabet M, Lao FS, Tawatao RI, Chan M, Smee DF, Julander JG, Cottam HB, Guiney DG, Corr M, Carson DA, Hayashi T. PMID: 24192551.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    18. Extraction protocol and mass spectrometry method for quantification of doxorubicin released locally from prodrugs in tumor tissue. J Mass Spectrom. 2013 Jul; 48(7):768-73. Ibsen S, Su Y, Norton J, Zahavy E, Hayashi T, Adams S, Wrasidlo W, Esener S. PMID: 23832932.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    19. Identification of substituted pyrimido[5,4-b]indoles as selective Toll-like receptor 4 ligands. J Med Chem. 2013 Jun 13; 56(11):4206-23. Chan M, Hayashi T, Mathewson RD, Nour A, Hayashi Y, Yao S, Tawatao RI, Crain B, Tsigelny IF, Kouznetsova VL, Messer K, Pu M, Corr M, Carson DA, Cottam HB. PMID: 23656327.
      View in: PubMed   Mentions: 27     Fields:    Translation:HumansAnimalsCells
    20. Localized in vivo activation of a photoactivatable doxorubicin prodrug in deep tumor tissue. Photochem Photobiol. 2013 May-Jun; 89(3):698-708. Ibsen S, Zahavy E, Wrasidlo W, Hayashi T, Norton J, Su Y, Adams S, Esener S. PMID: 23311544.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    21. Treatment of autoimmune inflammation by a TLR7 ligand regulating the innate immune system. PLoS One. 2012; 7(9):e45860. Hayashi T, Yao S, Crain B, Chan M, Tawatao RI, Gray C, Vuong L, Lao F, Cottam HB, Carson DA, Corr M. PMID: 23029281.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    22. Analysis of high-throughput screening assays using cluster enrichment. Stat Med. 2012 Dec 30; 31(30):4175-89. Pu M, Hayashi T, Cottam H, Mulvaney J, Arkin M, Corr M, Carson D, Messer K. PMID: 22763983.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    23. Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1. J Immunol. 2012 Apr 01; 188(7):2977-80. Norton JT, Hayashi T, Crain B, Cho JS, Miller LS, Corr M, Carson DA. PMID: 22387558.
      View in: PubMed   Mentions: 6     Fields:    Translation:AnimalsCells
    24. Mast cell-mediated inhibition of abdominal neutrophil inflammation by a PEGylated TLR7 ligand. Mediators Inflamm. 2012; 2012:262394. Hayashi T, Yao S, Crain B, Chan M, Cottam HB, Lao F, Carson DA, Corr M. PMID: 22619481.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    25. Importance of Toll-like receptor 9 in host defense against M1T1 group A Streptococcus infections. J Innate Immun. 2012; 4(2):213-8. Zinkernagel AS, Hruz P, Uchiyama S, von Köckritz-Blickwede M, Schuepbach RA, Hayashi T, Carson DA, Nizet V. PMID: 21860217.
      View in: PubMed   Mentions: 14     Fields:    Translation:AnimalsCells
    26. Role of IL-1 receptor-associated kinase-M (IRAK-M) in priming of immune and inflammatory responses by nitrogen bisphosphonates. Proc Natl Acad Sci U S A. 2011 Jul 05; 108(27):11163-8. Norton JT, Hayashi T, Crain B, Corr M, Carson DA. PMID: 21690387.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    27. Synthesis and characterization of PEGylated toll like receptor 7 ligands. Bioconjug Chem. 2011 Mar 16; 22(3):445-54. Chan M, Hayashi T, Mathewson RD, Yao S, Gray C, Tawatao RI, Kalenian K, Zhang Y, Hayashi Y, Lao FS, Cottam HB, Carson DA. PMID: 21338093.
      View in: PubMed   Mentions: 12     Fields:    Translation:HumansAnimalsCells
    28. Additive melanoma suppression with intralesional phospholipid-conjugated TLR7 agonists and systemic IL-2. Melanoma Res. 2011 Feb; 21(1):66-75. Hayashi T, Chan M, Norton JT, Wu CC, Yao S, Cottam HB, Tawatao RI, Corr M, Carson DA, Daniels GA. PMID: 21030882.
      View in: PubMed   Mentions: 7     Fields:    Translation:AnimalsCells
    29. Nrf2 responses and the therapeutic selectivity of electrophilic compounds in chronic lymphocytic leukemia. Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16):7479-84. Wu RP, Hayashi T, Cottam HB, Jin G, Yao S, Wu CC, Rosenbach MD, Corr M, Schwab RB, Carson DA. PMID: 20368435.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansCells
    30. Intravesical Toll-like receptor 7 agonist R-837: optimization of its formulation in an orthotopic mouse model of bladder cancer. Int J Urol. 2010 May; 17(5):483-90. Hayashi T, Crain B, Corr M, Chan M, Cottam HB, Maj R, Barberis A, Leoni L, Carson DA. PMID: 20337728.
      View in: PubMed   Mentions: 5     Fields:    Translation:Animals
    31. Synthesis and immunological characterization of toll-like receptor 7 agonistic conjugates. Bioconjug Chem. 2009 Jun; 20(6):1194-200. Chan M, Hayashi T, Kuy CS, Gray CS, Wu CC, Corr M, Wrasidlo W, Cottam HB, Carson DA. PMID: 19445505.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    32. In vivo efficacy of a phosphodiester TLR-9 aptamer and its beneficial effect in a pulmonary anthrax infection model. Cell Immunol. 2008 Feb; 251(2):78-85. Wu CC, Sabet M, Hayashi T, Tawatao R, Fierer J, Carson DA, Guiney DG, Corr M. PMID: 18495099.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCellsPHPublic Health
    33. Mast cell-dependent anorexia and hypothermia induced by mucosal activation of Toll-like receptor 7. . 2008 Jul; 295(1):R123-32. Hayashi T, Cottam HB, Chan M, Jin G, Tawatao RI, Crain B, Ronacher L, Messer K, Carson DA, Corr M. PMID: 18480244.
      View in: PubMed   Mentions:
    34. 3-Hydroxyanthranilic acid inhibits PDK1 activation and suppresses experimental asthma by inducing T cell apoptosis. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18619-24. Hayashi T, Mo JH, Gong X, Rossetto C, Jang A, Beck L, Elliott GI, Kufareva I, Abagyan R, Broide DH, Lee J, Raz E. PMID: 18003900.
      View in: PubMed   Mentions: 48     Fields:    Translation:HumansAnimalsCells
    35. Immunotherapeutic activity of a conjugate of a Toll-like receptor 7 ligand. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):3990-5. Wu CC, Hayashi T, Takabayashi K, Sabet M, Smee DF, Guiney DD, Cottam HB, Carson DA. PMID: 17360465.
      View in: PubMed   Mentions: 43     Fields:    Translation:Animals
    36. TLR9-based immunotherapy for allergic disease. Am J Med. 2006 Oct; 119(10):897.e1-6. Hayashi T, Raz E. PMID: 17000223.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    37. Vaccination with irradiated Listeria induces protective T cell immunity. Immunity. 2006 Jul; 25(1):143-52. Datta SK, Okamoto S, Hayashi T, Shin SS, Mihajlov I, Fermin A, Guiney DG, Fierer J, Raz E. PMID: 16860763.
      View in: PubMed   Mentions: 32     Fields:    Translation:AnimalsCellsPHPublic Health
    38. Induction of a homeostatic circuit in lung tissue by microbial compounds. Immunity. 2006 Apr; 24(4):475-87. Takabayshi K, Corr M, Hayashi T, Redecke V, Beck L, Guiney D, Sheppard D, Raz E. PMID: 16618605.
      View in: PubMed   Mentions: 24     Fields:    Translation:AnimalsCells
    39. CpG oligonucleotides partially inhibit growth of Mycobacterium tuberculosis, but not Salmonella or Listeria, in human monocyte-derived macrophages. FEMS Immunol Med Microbiol. 2005 Aug 01; 45(2):303-10. Wang JP, Hayashi T, Datta SK, Kornbluth RS, Raz E, Guiney DG. PMID: 16002269.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    40. Induction and inhibition of the Th2 phenotype spread: implications for childhood asthma. J Immunol. 2005 May 01; 174(9):5864-73. Hayashi T, Gong X, Rossetto C, Shen C, Takabayashi K, Redecke V, Spiegelberg H, Broide D, Raz E. PMID: 15843591.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    41. Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J Clin Invest. 2004 Jul; 114(2):270-9. Hayashi T, Beck L, Rossetto C, Gong X, Takikawa O, Takabayashi K, Broide DH, Carson DA, Raz E. PMID: 15254594.
      View in: PubMed   Mentions: 89     Fields:    Translation:AnimalsCells
    42. Airway peptidoglycan and immunostimulatory DNA exposures have divergent effects on the development of airway allergen hypersensitivities. J Allergy Clin Immunol. 2004 Mar; 113(3):448-54. Chisholm D, Libet L, Hayashi T, Horner AA. PMID: 15007346.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCellsPHPublic Health
    43. Identification of a chemotactic, MCP-1-like protein from Mycobacterium avium. FEMS Immunol Med Microbiol. 2002 Jun 03; 33(2):115-24. Rao SP, Hayashi T, Catanzaro A. PMID: 12052566.
      View in: PubMed   Mentions:    Fields:    Translation:HumansCells
    Tomoko's Networks
    Concepts (291)
    Derived automatically from this person's publications.
    _
    Co-Authors (35)
    People in Profiles who have published with this person.
    _
    Similar People (60)
    People who share similar concepts with this person.
    _
    Same Department
    Search Department
    _