Jill Mesirov

Title(s)Professor, Medicine
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    The Integrative Genomics Viewer (IGV) for Cancer Research
    NIH U24CA258406Sep 7, 2021 - Aug 31, 2026
    Role: Principal Investigator
    Identifying therapeutic pathways targeting medulloblastoma-immune cell interactions
    NIH U01CA253547May 1, 2021 - Apr 30, 2026
    Role: Co-Principal Investigator
    GenePattern and GenePattern Notebook: Integrative 'Omic Analysis for Cancer Research
    NIH U24CA248457Jun 1, 2020 - May 31, 2025
    Role: Principal Investigator
    Supporting and evolving Gene Set Enrichment Analysis and the Molecular Signatures Database for cancer research
    NIH U24CA220341May 1, 2018 - Apr 30, 2023
    Role: Principal Investigator
    A Rational Systematic Approach to Find Combinations of Pharmacologic and Immune Therapies that Target Identifiable Oncogenic States
    NIH U01CA217885Sep 12, 2017 - Jul 31, 2022
    Role: Co-Principal Investigator
    The Integrative Genomics Viewer (IGV): visualization supporting cancer research
    NIH U24CA210004Sep 1, 2016 - Aug 31, 2021
    Role: Principal Investigator
    GenePattern Notebooks for Cancer Research
    NIH U24CA194107Apr 1, 2015 - Mar 31, 2021
    Role: Principal Investigator
    Embryonal Brain Tumor Networks
    NIH U01CA184898Jul 1, 2014 - May 31, 2021
    Role: Principal Investigator
    GenomeSpace: community web environment for analysis across diverse genomic tools
    NIH U41HG007517Mar 17, 2014 - Feb 29, 2020
    Role: Principal Investigator
    A next-generation Integrative Genomics Viewer for biomedical and cancer research.
    NIH R01CA157304Jul 1, 2012 - Apr 30, 2017
    Role: Principal Investigator
    MIT-Harvard Center of Cancer Nanotechnology Excellence
    NIH U54CA151884Sep 1, 2010 - Jul 31, 2015
    Role: Co-Investigator
    GenomeSpace: A community web environment for integrative genomic analysis
    NIH P01HG005062Sep 11, 2009 - Mar 16, 2014
    Role: Principal Investigator
    An Integrative Genomics Data Viewer to Support the TCGA Project
    NIH R21CA135827Sep 12, 2008 - Aug 31, 2011
    Role: Principal Investigator
    Knowledge-based Gene Expression Analysis for Biomedical and Cancer Research
    NIH R01CA121941Aug 1, 2006 - Apr 30, 2018
    Role: Principal Investigator
    Supporting Integrative Genomic Analysis Users with GenePattern
    NIH R01GM074024Jun 1, 2005 - Nov 30, 2020
    Role: Principal Investigator
    Broad Institute Center for Cancer Systems Biology
    NIH U54CA112962Sep 30, 2004 - Feb 28, 2015
    Role: Co-Investigator
    Genomic Analysis of Medulloblastomas
    NIH R01CA109467Aug 1, 2004 - May 31, 2018
    Role: Principal Investigator
    GenePattern: Methodologies and Software Tools.
    NIH R33CA097556Jul 1, 2002 - Jun 30, 2006
    Role: Principal Investigator
    NATIONAL BIOMEDICAL COMPUTATION RESOURCE
    NIH P41RR008605Apr 15, 1994 - Apr 30, 2014
    Role: Co-Investigator
    Cancer Center Support (Core) Grant
    NIH P30CA014051Sep 1, 1975 - Apr 30, 2020
    Role: Co-Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Developmental basis of SHH medulloblastoma heterogeneity. Nat Commun. 2024 Jan 08; 15(1):270. Gold MP, Ong W, Masteller AM, Ghasemi DR, Galindo JA, Park NR, Huynh NC, Donde A, Pister V, Saurez RA, Vladoiu MC, Hwang GH, Eisemann T, Donovan LK, Walker AD, Benetatos J, Dufour C, Garzia L, Segal RA, Wechsler-Reya RJ, Mesirov JP, Korshunov A, Pajtler KW, Pomeroy SL, Ayrault O, Davidson SM, Cotter JA, Taylor MD, Fraenkel E. PMID: 38191555; PMCID: PMC10774283.
      View in: PubMed   Mentions:    Fields:    Translation:Humans
    2. NMF Clustering: Accessible NMF-based Clustering Utilizing GPU Acceleration. J Bioinform Syst Biol. 2023; 6(4):379-383. Liefeld T, Huang E, Wenzel AT, Yoshimoto K, Sharma AK, Sicklick JK, Mesirov JP, Reich M. PMID: 38390437; PMCID: PMC10883375.
      View in: PubMed   Mentions:
    3. Inferring cellular and molecular processes in single-cell data with non-negative matrix factorization using Python, R and GenePattern Notebook implementations of CoGAPS. Nat Protoc. 2023 Dec; 18(12):3690-3731. Johnson JAI, Tsang AP, Mitchell JT, Zhou DL, Bowden J, Davis-Marcisak E, Sherman T, Liefeld T, Loth M, Goff LA, Zimmerman JW, Kinny-Köster B, Jaffee EM, Tamayo P, Mesirov JP, Reich M, Fertig EJ, Stein-O'Brien GL. PMID: 37989764; PMCID: PMC10961825.
      View in: PubMed   Mentions:    Fields:    
    4. Deciphering the Functional Roles of Individual Cancer Alleles Across Comprehensive Cancer Genomic Studies. bioRxiv. 2023 Nov 16. Ma JY, Ting S, Tam B, Pham T, Reich M, Mesirov J, Tamayo P, Kim W. PMID: 38014215; PMCID: PMC10680728.
      View in: PubMed   Mentions:
    5. Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma. Nat Genet. 2023 Dec; 55(12):2189-2199. Chapman OS, Luebeck J, Sridhar S, Wong IT, Dixit D, Wang S, Prasad G, Rajkumar U, Pagadala MS, Larson JD, He BJ, Hung KL, Lange JT, Dehkordi SR, Chandran S, Adam M, Morgan L, Wani S, Tiwari A, Guccione C, Lin Y, Dutta A, Lo YY, Juarez E, Robinson JT, Korshunov A, Michaels JA, Cho YJ, Malicki DM, Coufal NG, Levy ML, Hobbs C, Scheuermann RH, Crawford JR, Pomeroy SL, Rich JN, Zhang X, Chang HY, Dixon JR, Bagchi A, Deshpande AJ, Carter H, Fraenkel E, Mischel PS, Wechsler-Reya RJ, Bafna V, Mesirov JP, Chavez L. PMID: 37945900; PMCID: PMC10703696.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    6. Extending support for mouse data in the Molecular Signatures Database (MSigDB). Nat Methods. 2023 Nov; 20(11):1619-1620. Castanza AS, Recla JM, Eby D, Thorvaldsdóttir H, Bult CJ, Mesirov JP. PMID: 37704782.
      View in: PubMed   Mentions: 3     Fields:    Translation:Animals
    7. NMFClustering: Accessible NMF-based clustering utilizing GPU acceleration. bioRxiv. 2023 Jun 27. Liefeld T, Huang E, Wenzel AT, Yoshimoto K, Sharma AK, Sicklick JK, Mesirov JP, Reich M. PMID: 37398372; PMCID: PMC10312797.
      View in: PubMed   Mentions:
    8. The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure. Nat Immunol. 2023 08; 24(8):1318-1330. Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. PMID: 37308665; PMCID: PMC10735169.
      View in: PubMed   Mentions: 3     Fields:    Translation:AnimalsCells
    9. Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response. Nat Commun. 2023 05 12; 14(1):2744. Pagadala M, Sears TJ, Wu VH, Pérez-Guijarro E, Kim H, Castro A, Talwar JV, Gonzalez-Colin C, Cao S, Schmiedel BJ, Goudarzi S, Kirani D, Au J, Zhang T, Landi T, Salem RM, Morris GP, Harismendy O, Patel SP, Alexandrov LB, Mesirov JP, Zanetti M, Day CP, Fan CC, Thompson WK, Merlino G, Gutkind JS, Vijayanand P, Carter H. PMID: 37173324; PMCID: PMC10182072.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    10. 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nat Commun. 2023 04 21; 14(1):2300. Okonechnikov K, Camgöz A, Chapman O, Wani S, Park DE, Hübner JM, Chakraborty A, Pagadala M, Bump R, Chandran S, Kraft K, Acuna-Hidalgo R, Reid D, Sikkink K, Mauermann M, Juarez EF, Jenseit A, Robinson JT, Pajtler KW, Milde T, Jäger N, Fiesel P, Morgan L, Sridhar S, Coufal NG, Levy M, Malicki D, Hobbs C, Kingsmore S, Nahas S, Snuderl M, Crawford J, Wechsler-Reya RJ, Davidson TB, Cotter J, Michaiel G, Fleischhack G, Mundlos S, Schmitt A, Carter H, Michealraj KA, Kumar SA, Taylor MD, Rich J, Buchholz F, Mesirov JP, Pfister SM, Ay F, Dixon JR, Kool M, Chavez L. PMID: 37085539; PMCID: PMC10121654.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    11. Genomics to Notebook (g2nb): extending the electronic notebook to address the challenges of bioinformatics analysis. bioRxiv. 2023 Apr 06. Reich M, Tabor T, Liefeld J, Joshi J, Kim F, Thorvaldsdottir H, Blankenberg D, Mesirov JP. PMID: 37066251; PMCID: PMC10104038.
      View in: PubMed   Mentions:
    12. igv.js: an embeddable JavaScript implementation of the Integrative Genomics Viewer (IGV). Bioinformatics. 2023 01 01; 39(1). Robinson JT, Thorvaldsdottir H, Turner D, Mesirov JP. PMID: 36562559; PMCID: PMC9825295.
      View in: PubMed   Mentions: 70     Fields:    
    13. Subgroup-Enriched Pathways and Kinase Signatures in Medulloblastoma Patient-Derived Xenografts. J Proteome Res. 2022 09 02; 21(9):2124-2136. Leskoske KL, Garcia-Mansfield K, Sharma R, Krishnan A, Rusert JM, Mesirov JP, Wechsler-Reya RJ, Pirrotte P. PMID: 35977718; PMCID: PMC9442791.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimals
    14. Lymphatic-preserving treatment sequencing with immune checkpoint inhibition unleashes cDC1-dependent antitumor immunity in HNSCC. Nat Commun. 2022 07 25; 13(1):4298. Saddawi-Konefka R, O'Farrell A, Faraji F, Clubb L, Allevato MM, Jensen SM, Yung BS, Wang Z, Wu VH, Anang NA, Msari RA, Schokrpur S, Pietryga IF, Molinolo AA, Mesirov JP, Simon AB, Fox BA, Bui JD, Sharabi A, Cohen EEW, Califano JA, Gutkind JS. PMID: 35879302; PMCID: PMC9314425.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansAnimalsCells
    15. Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer. NPJ Syst Biol Appl. 2022 06 17; 8(1):20. Wenzel AT, Champa D, Venkatesh H, Sun S, Tsai CY, Mesirov JP, Bui JD, Howell SB, Harismendy O. PMID: 35715421; PMCID: PMC9206019.
      View in: PubMed   Mentions: 1     Fields:    Translation:Humans
    16. A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models. Mol Cancer Ther. 2022 01; 21(1):113-124. Do M, Wu CCN, Sonavane PR, Juarez EF, Adams SR, Ross J, Rodriguez Y Baena A, Patel C, Mesirov JP, Carson DA, Advani SJ, Willert K. PMID: 34667113; PMCID: PMC8742765.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansAnimalsCells
    17. Location of Gastrointestinal Stromal Tumor (GIST) in the Stomach Predicts Tumor Mutation Profile and Drug Sensitivity. Clin Cancer Res. 2021 10 01; 27(19):5334-5342. Sharma AK, de la Torre J, IJzerman NS, Sutton TL, Zhao B, Khan TM, Banerjee S, Cui C, Nguyen V, Alkhuziem M, Snaebjornsson P, van Boven H, Bruining A, Tang CM, Yoon H, De la Fuente A, Kato S, Patel H, Heinrich MC, Corless CL, Horgan S, Burgoyne AM, Fanta P, Mesirov JP, Blakely AM, Davis JL, Mayo SC, van Houdt WJ, Steeghs N, Sicklick JK. PMID: 34326133; PMCID: PMC8799780.
      View in: PubMed   Mentions: 6     Fields:    Translation:Humans
    18. KITlow Cells Mediate Imatinib Resistance in Gastrointestinal Stromal Tumor. Mol Cancer Ther. 2021 10; 20(10):2035-2048. Banerjee S, Yoon H, Ting S, Tang CM, Yebra M, Wenzel AT, Yeerna H, Mesirov JP, Wechsler-Reya RJ, Tamayo P, Sicklick JK. PMID: 34376580; PMCID: PMC8492542.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    19. PTEN deficiency leads to proteasome addiction: a novel vulnerability in glioblastoma. Neuro Oncol. 2021 07 01; 23(7):1072-1086. Benitez JA, Finlay D, Castanza A, Parisian AD, Ma J, Longobardi C, Campos A, Vadla R, Izurieta A, Scerra G, Koga T, Long T, Chavez L, Mesirov JP, Vuori K, Furnari F. PMID: 33428749; PMCID: PMC8661409.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    20. Model-based assessment of mammalian cell metabolic functionalities using omics data. Cell Rep Methods. 2021 07 26; 1(3). Richelle A, Kellman BP, Wenzel AT, Chiang AWT, Reagan T, Gutierrez JM, Joshi C, Li S, Liu JK, Masson H, Lee J, Li Z, Heirendt L, Trefois C, Juarez EF, Bath T, Borland D, Mesirov JP, Robasky K, Lewis NE. PMID: 34761247; PMCID: PMC8577426.
      View in: PubMed   Mentions: 13  Translation:AnimalsCells
    21. A phenotypically supervised single-cell analysis protocol to study within-cell-type heterogeneity of cultured mammalian cells. STAR Protoc. 2021 06 18; 2(2):100561. Chen K, Ozturk K, Liefeld T, Reich M, Mesirov JP, Carter H, Fraley SI. PMID: 34095869; PMCID: PMC8165572.
      View in: PubMed   Mentions:    Fields:    Translation:HumansAnimalsCells
    22. TORC1/2 kinase inhibition depletes glutathione and synergizes with carboplatin to suppress the growth of MYC-driven medulloblastoma. Cancer Lett. 2021 04 28; 504:137-145. Maynard RE, Poore B, Hanaford AR, Pham K, James M, Alt J, Park Y, Slusher BS, Tamayo P, Mesirov J, Archer TC, Pomeroy SL, Eberhart CG, Raabe EH. PMID: 33571541; PMCID: PMC9195565.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimals
    23. Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma. Cancer Res. 2020 12 01; 80(23):5393-5407. Rusert JM, Juarez EF, Brabetz S, Jensen J, Garancher A, Chau LQ, Tacheva-Grigorova SK, Wahab S, Udaka YT, Finlay D, Seker-Cin H, Reardon B, Gröbner S, Serrano J, Ecker J, Qi L, Kogiso M, Du Y, Baxter PA, Henderson JJ, Berens ME, Vuori K, Milde T, Cho YJ, Li XN, Olson JM, Reyes I, Snuderl M, Wong TC, Dimmock DP, Nahas SA, Malicki D, Crawford JR, Levy ML, Van Allen EM, Pfister SM, Tamayo P, Kool M, Mesirov JP, Wechsler-Reya RJ. PMID: 33046443; PMCID: PMC7718387.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansAnimalsCells
    24. Imaging-AMARETTO: An Imaging Genomics Software Tool to Interrogate Multiomics Networks for Relevance to Radiography and Histopathology Imaging Biomarkers of Clinical Outcomes. JCO Clin Cancer Inform. 2020 05; 4:421-435. Gevaert O, Nabian M, Bakr S, Everaert C, Shinde J, Manukyan A, Liefeld T, Tabor T, Xu J, Lupberger J, Haas BJ, Baumert TF, Hernaez M, Reich M, Quintana FJ, Uhlmann EJ, Krichevsky AM, Mesirov JP, Carey V, Pochet N. PMID: 32383980; PMCID: PMC7265792.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    25. Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proc Natl Acad Sci U S A. 2019 12 03; 116(49):24881-24891. Banerjee S, Wei T, Wang J, Lee JJ, Gutierrez HL, Chapman O, Wiley SE, Mayfield JE, Tandon V, Juarez EF, Chavez L, Liang R, Sah RL, Costello C, Mesirov JP, de la Vega L, Cooper KL, Dixon JE, Xiao J, Lei X. PMID: 31754034; PMCID: PMC6900511.
      View in: PubMed   Mentions: 23     Fields:    Translation:HumansAnimalsCells
    26. Biallelic loss of GNAS in a patient with pediatric medulloblastoma. Cold Spring Harb Mol Case Stud. 2019 10; 5(5). Tokita MJ, Nahas S, Briggs B, Malicki DM, Mesirov JP, Reyes IAC, Farnaes L, Levy ML, Kingsmore SF, Dimmock D, Crawford JR, Wechsler-Reya RJ. PMID: 31624069; PMCID: PMC6824258.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    27. Precision Medicine: Improving health through high-resolution analysis of personal data. Pac Symp Biocomput. 2019; 24:220-223. Brenner SE, Bulyk M, Crawford DC, Mesirov JP, Morgan AA, Radivojac P. PMID: 30864324; PMCID: PMC6526370.
      View in: PubMed   Mentions:    Fields:    
    28. Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 2019 01; 565(7738):E5-E6. Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, Morais P, Meltzer J, Korejwa A, Jané-Valbuena J, Mapa FA, Thibault J, Bric-Furlong E, Raman P, Shipway A, Engels IH, Cheng J, Yu GK, Yu J, Aspesi P, de Silva M, Jagtap K, Jones MD, Wang L, Hatton C, Palescandolo E, Gupta S, Mahan S, Sougnez C, Onofrio RC, Liefeld T, MacConaill L, Winckler W, Reich M, Li N, Mesirov JP, Gabriel SB, Getz G, Ardlie K, Chan V, Myer VE, Weber BL, Porter J, Warmuth M, Finan P, Harris JL, Meyerson M, Golub TR, Morrissey MP, Sellers WR, Schlegel R, Garraway LA. PMID: 30559381.
      View in: PubMed   Mentions: 35     Fields:    
    29. A Curated Resource for Phosphosite-specific Signature Analysis. Mol Cell Proteomics. 2019 03; 18(3):576-593. Krug K, Mertins P, Zhang B, Hornbeck P, Raju R, Ahmad R, Szucs M, Mundt F, Forestier D, Jane-Valbuena J, Keshishian H, Gillette MA, Tamayo P, Mesirov JP, Jaffe JD, Carr SA, Mani DR. PMID: 30563849; PMCID: PMC6398202.
      View in: PubMed   Mentions: 98     Fields:    Translation:HumansAnimalsCells
    30. An accessible GenePattern notebook for the copy number variation analysis of Illumina Infinium DNA methylation arrays. F1000Res. 2018; 7. Mah CK, Mesirov JP, Chavez L. PMID: 31105932; PMCID: PMC6498745.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
    31. Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups. Cancer Cell. 2018 09 10; 34(3):396-410.e8. Archer TC, Ehrenberger T, Mundt F, Gold MP, Krug K, Mah CK, Mahoney EL, Daniel CJ, LeNail A, Ramamoorthy D, Mertins P, Mani DR, Zhang H, Gillette MA, Clauser K, Noble M, Tang LC, Pierre-François J, Silterra J, Jensen J, Tamayo P, Korshunov A, Pfister SM, Kool M, Northcott PA, Sears RC, Lipton JO, Carr SA, Mesirov JP, Pomeroy SL, Fraenkel E. PMID: 30205044; PMCID: PMC6372116.
      View in: PubMed   Mentions: 86     Fields:    Translation:HumansCells
    32. An accessible, interactive GenePattern Notebook for analysis and exploration of single-cell transcriptomic data. F1000Res. 2018; 7:1306. Mah CK, Tabor T, Mesirov JP. PMID: 31316748; PMCID: PMC6611141.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    33. GeNets: a unified web platform for network-based genomic analyses. Nat Methods. 2018 07; 15(7):543-546. Li T, Kim A, Rosenbluh J, Horn H, Greenfeld L, An D, Zimmer A, Liberzon A, Bistline J, Natoli T, Li Y, Tsherniak A, Narayan R, Subramanian A, Liefeld T, Wong B, Thompson D, Calvo S, Carr S, Boehm J, Jaffe J, Mesirov J, Hacohen N, Regev A, Lage K. PMID: 29915188; PMCID: PMC6450090.
      View in: PubMed   Mentions: 33     Fields:    
    34. Juicebox.js Provides a Cloud-Based Visualization System for Hi-C Data. Cell Syst. 2018 Feb 28; 6(2):256-258.e1. Robinson JT, Turner D, Durand NC, Thorvaldsdóttir H, Mesirov JP, Aiden EL. PMID: 29428417; PMCID: PMC6047755.
      View in: PubMed   Mentions: 164     Fields:    
    35. Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2. Cell Rep. 2017 Dec 05; 21(10):2688-2695. Hachigian LJ, Carmona V, Fenster RJ, Kulicke R, Heilbut A, Sittler A, Pereira de Almeida L, Mesirov JP, Gao F, Kolaczyk ED, Heiman M. PMID: 29212017.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimals
    36. Variant Review with the Integrative Genomics Viewer. Cancer Res. 2017 11 01; 77(21):e31-e34. Robinson JT, Thorvaldsdóttir H, Wenger AM, Zehir A, Mesirov JP. PMID: 29092934; PMCID: PMC5678989.
      View in: PubMed   Mentions: 455     Fields:    Translation:Humans
    37. Decomposing Oncogenic Transcriptional Signatures to Generate Maps of Divergent Cellular States. Cell Syst. 2017 08 23; 5(2):105-118.e9. Kim JW, Abudayyeh OO, Yeerna H, Yeang CH, Stewart M, Jenkins RW, Kitajima S, Konieczkowski DJ, Medetgul-Ernar K, Cavazos T, Mah C, Ting S, Van Allen EM, Cohen O, Mcdermott J, Damato E, Aguirre AJ, Liang J, Liberzon A, Alexe G, Doench J, Ghandi M, Vazquez F, Weir BA, Tsherniak A, Subramanian A, Meneses-Cime K, Park J, Clemons P, Garraway LA, Thomas D, Boehm JS, Barbie DA, Hahn WC, Mesirov JP, Tamayo P. PMID: 28837809; PMCID: PMC5639711.
      View in: PubMed   Mentions: 24     Fields:    Translation:HumansCells
    38. The GenePattern Notebook Environment. Cell Syst. 2017 08 23; 5(2):149-151.e1. Reich M, Tabor T, Liefeld T, Thorvaldsdóttir H, Hill B, Tamayo P, Mesirov JP. PMID: 28822753; PMCID: PMC5572818.
      View in: PubMed   Mentions: 13     Fields:    
    39. Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway. Nature. 2017 07 27; 547(7664):453-457. Viswanathan VS, Ryan MJ, Dhruv HD, Gill S, Eichhoff OM, Seashore-Ludlow B, Kaffenberger SD, Eaton JK, Shimada K, Aguirre AJ, Viswanathan SR, Chattopadhyay S, Tamayo P, Yang WS, Rees MG, Chen S, Boskovic ZV, Javaid S, Huang C, Wu X, Tseng YY, Roider EM, Gao D, Cleary JM, Wolpin BM, Mesirov JP, Haber DA, Engelman JA, Boehm JS, Kotz JD, Hon CS, Chen Y, Hahn WC, Levesque MP, Doench JG, Berens ME, Shamji AF, Clemons PA, Stockwell BR, Schreiber SL. PMID: 28678785; PMCID: PMC5667900.
      View in: PubMed   Mentions: 662     Fields:    Translation:HumansCells
    40. A multi-tool recipe to identify regions of protein-DNA binding and their influence on associated gene expression. F1000Res. 2017; 6:784. Carlin D, Kosnicki K, Garamszegi S, Ideker T, Thorvaldsdóttir H, Reich M, Mesirov J. PMID: 29487738; PMCID: PMC5806050.
      View in: PubMed   Mentions:    Fields:    
    41. Exome Sequencing of African-American Prostate Cancer Reveals Loss-of-Function ERF Mutations. Cancer Discov. 2017 09; 7(9):973-983. Huang FW, Mosquera JM, Garofalo A, Oh C, Baco M, Amin-Mansour A, Rabasha B, Bahl S, Mullane SA, Robinson BD, Aldubayan S, Khani F, Karir B, Kim E, Chimene-Weiss J, Hofree M, Romanel A, Osborne JR, Kim JW, Azabdaftari G, Woloszynska-Read A, Sfanos K, De Marzo AM, Demichelis F, Gabriel S, Van Allen EM, Mesirov J, Tamayo P, Rubin MA, Powell IJ, Garraway LA. PMID: 28515055; PMCID: PMC5836784.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    42. OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma. Cancer Discov. 2017 03; 7(3):288-301. Boulay G, Awad ME, Riggi N, Archer TC, Iyer S, Boonseng WE, Rossetti NE, Naigles B, Rengarajan S, Volorio A, Kim JC, Mesirov JP, Tamayo P, Pomeroy SL, Aryee MJ, Rivera MN. PMID: 28213356; PMCID: PMC5340587.
      View in: PubMed   Mentions: 29     Fields:    Translation:HumansCells
    43. Transcriptional Categorization of the Etiology of Pneumonia Syndrome in Pediatric Patients in Malaria-Endemic Areas. J Infect Dis. 2017 01 15; 215(2):312-320. Silterra J, Gillette MA, Lanaspa M, Pellé KG, Valim C, Ahmad R, Acácio S, Almendinger KD, Tan Y, Madrid L, Alonso PL, Carr SA, Wiegand RC, Bassat Q, Mesirov JP, Milner DA, Wirth DF. PMID: 27837008; PMCID: PMC6392473.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    44. Leveraging premalignant biology for immune-based cancer prevention. Proc Natl Acad Sci U S A. 2016 09 27; 113(39):10750-8. Spira A, Disis ML, Schiller JT, Vilar E, Rebbeck TR, Bejar R, Ideker T, Arts J, Yurgelun MB, Mesirov JP, Rao A, Garber J, Jaffee EM, Lippman SM. PMID: 27638202; PMCID: PMC5047191.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    45. Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom. Cell Syst. 2016 07; 3(1):99-101. Durand NC, Robinson JT, Shamim MS, Machol I, Mesirov JP, Lander ES, Aiden EL. PMID: 27467250; PMCID: PMC5596920.
      View in: PubMed   Mentions: 669     Fields:    Translation:Humans
    46. Kataegis Expression Signature in Breast Cancer Is Associated with Late Onset, Better Prognosis, and Higher HER2 Levels. Cell Rep. 2016 07 19; 16(3):672-83. D'Antonio M, Tamayo P, Mesirov JP, Frazer KA. PMID: 27373164; PMCID: PMC4972030.
      View in: PubMed   Mentions: 17     Fields:    Translation:HumansCells
    47. RNA Duplex Map in Living Cells Reveals Higher-Order Transcriptome Structure. Cell. 2016 May 19; 165(5):1267-1279. Lu Z, Zhang QC, Lee B, Flynn RA, Smith MA, Robinson JT, Davidovich C, Gooding AR, Goodrich KJ, Mattick JS, Mesirov JP, Cech TR, Chang HY. PMID: 27180905; PMCID: PMC5029792.
      View in: PubMed   Mentions: 300     Fields:    Translation:HumansAnimalsCells
    48. Characterizing genomic alterations in cancer by complementary functional associations. Nat Biotechnol. 2016 05; 34(5):539-46. Kim JW, Botvinnik OB, Abudayyeh O, Birger C, Rosenbluh J, Shrestha Y, Abazeed ME, Hammerman PS, DiCara D, Konieczkowski DJ, Johannessen CM, Liberzon A, Alizad-Rahvar AR, Alexe G, Aguirre A, Ghandi M, Greulich H, Vazquez F, Weir BA, Van Allen EM, Tsherniak A, Shao DD, Zack TI, Noble M, Getz G, Beroukhim R, Garraway LA, Ardakani M, Romualdi C, Sales G, Barbie DA, Boehm JS, Hahn WC, Mesirov JP, Tamayo P. PMID: 27088724; PMCID: PMC4868596.
      View in: PubMed   Mentions: 50     Fields:    Translation:HumansCells
    49. DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets. Clin Cancer Res. 2016 08 01; 22(15):3903-14. Hanaford AR, Archer TC, Price A, Kahlert UD, Maciaczyk J, Nikkhah G, Kim JW, Ehrenberger T, Clemons PA, Dancík V, Seashore-Ludlow B, Viswanathan V, Stewart ML, Rees MG, Shamji A, Schreiber S, Fraenkel E, Pomeroy SL, Mesirov JP, Tamayo P, Eberhart CG, Raabe EH. PMID: 27012813; PMCID: PMC5055054.
      View in: PubMed   Mentions: 39     Fields:    Translation:HumansAnimalsCells
    50. Responses to Bacteria, Virus, and Malaria Distinguish the Etiology of Pediatric Clinical Pneumonia. Am J Respir Crit Care Med. 2016 Feb 15; 193(4):448-59. Valim C, Ahmad R, Lanaspa M, Tan Y, Acácio S, Gillette MA, Almendinger KD, Milner DA, Madrid L, Pellé K, Harezlak J, Silterra J, Alonso PL, Carr SA, Mesirov JP, Wirth DF, Wiegand RC, Bassat Q. PMID: 26469764; PMCID: PMC5440057.
      View in: PubMed   Mentions: 27     Fields:    Translation:Humans
    51. Integrative genomic analysis by interoperation of bioinformatics tools in GenomeSpace. Nat Methods. 2016 Mar; 13(3):245-247. Qu K, Garamszegi S, Wu F, Thorvaldsdottir H, Liefeld T, Ocana M, Borges-Rivera D, Pochet N, Robinson JT, Demchak B, Hull T, Ben-Artzi G, Blankenberg D, Barber GP, Lee BT, Kuhn RM, Nekrutenko A, Segal E, Ideker T, Reich M, Regev A, Chang HY, Mesirov JP. PMID: 26780094; PMCID: PMC4767623.
      View in: PubMed   Mentions: 14     Fields:    Translation:Humans
    52. Compendium of Immune Signatures Identifies Conserved and Species-Specific Biology in Response to Inflammation. Immunity. 2016 Jan 19; 44(1):194-206. Godec J, Tan Y, Liberzon A, Tamayo P, Bhattacharya S, Butte AJ, Mesirov JP, Haining WN. PMID: 26795250; PMCID: PMC5330663.
      View in: PubMed   Mentions: 147     Fields:    Translation:HumansAnimalsCells
    53. The Molecular Signatures Database (MSigDB) hallmark gene set collection. Cell Syst. 2015 Dec 23; 1(6):417-425. Liberzon A, Birger C, Thorvaldsdóttir H, Ghandi M, Mesirov JP, Tamayo P. PMID: 26771021; PMCID: PMC4707969.
      View in: PubMed   Mentions: 4651     Fields:    
    54. Role of Tet1/3 Genes and Chromatin Remodeling Genes in Cerebellar Circuit Formation. Neuron. 2016 Jan 06; 89(1):100-12. Zhu X, Girardo D, Govek EE, John K, Mellén M, Tamayo P, Mesirov JP, Hatten ME. PMID: 26711116; PMCID: PMC4707072.
      View in: PubMed   Mentions: 48     Fields:    Translation:AnimalsCells
    55. Constellation Map: Downstream visualization and interpretation of gene set enrichment results. F1000Res. 2015; 4:167. Tan Y, Wu F, Tamayo P, Haining WN, Mesirov JP. PMID: 26594333; PMCID: PMC4648224.
      View in: PubMed   Mentions: 3     Fields:    
    56. A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation. PLoS One. 2015; 10(3):e0116096. Papageorgiou A, Rapley J, Mesirov JP, Tamayo P, Avruch J. PMID: 25790369; PMCID: PMC4366019.
      View in: PubMed   Mentions: 4     Fields:    Translation:HumansAnimalsCells
    57. A functional landscape of resistance to ALK inhibition in lung cancer. Cancer Cell. 2015 Mar 09; 27(3):397-408. Wilson FH, Johannessen CM, Piccioni F, Tamayo P, Kim JW, Van Allen EM, Corsello SM, Capelletti M, Calles A, Butaney M, Sharifnia T, Gabriel SB, Mesirov JP, Hahn WC, Engelman JA, Meyerson M, Root DE, Jänne PA, Garraway LA. PMID: 25759024; PMCID: PMC4398996.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    58. A genomic data viewer for iPad. Genome Biol. 2015 Feb 26; 16:46. Thorvaldsdóttir H, Robinson JT, Turner D, Mesirov JP. PMID: 25723152; PMCID: PMC4342165.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    59. Quantitative visualization of alternative exon expression from RNA-seq data. Bioinformatics. 2015 Jul 15; 31(14):2400-2. Katz Y, Wang ET, Silterra J, Schwartz S, Wong B, Thorvaldsdóttir H, Robinson JT, Mesirov JP, Airoldi EM, Burge CB. PMID: 25617416; PMCID: PMC4542614.
      View in: PubMed   Mentions: 97     Fields:    Translation:HumansCells
    60. Plasmodium falciparum gene expression measured directly from tissue during human infection. Genome Med. 2014; 6(11):110. Van Tyne D, Tan Y, Daily JP, Kamiza S, Seydel K, Taylor T, Mesirov JP, Wirth DF, Milner DA. PMID: 25520756; PMCID: PMC4269068.
      View in: PubMed   Mentions: 4     Fields:    
    61. Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth. J Clin Invest. 2014 Dec; 124(12):5411-23. Barbie TU, Alexe G, Aref AR, Li S, Zhu Z, Zhang X, Imamura Y, Thai TC, Huang Y, Bowden M, Herndon J, Cohoon TJ, Fleming T, Tamayo P, Mesirov JP, Ogino S, Wong KK, Ellis MJ, Hahn WC, Barbie DA, Gillanders WE. PMID: 25365225; PMCID: PMC4348940.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    62. Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies. Sci Data. 2014; 1:140035. Cowley GS, Weir BA, Vazquez F, Tamayo P, Scott JA, Rusin S, East-Seletsky A, Ali LD, Gerath WF, Pantel SE, Lizotte PH, Jiang G, Hsiao J, Tsherniak A, Dwinell E, Aoyama S, Okamoto M, Harrington W, Gelfand E, Green TM, Tomko MJ, Gopal S, Wong TC, Wong TC, Li H, Howell S, Stransky N, Liefeld T, Jang D, Bistline J, Hill Meyers B, Armstrong SA, Anderson KC, Stegmaier K, Reich M, Pellman D, Boehm JS, Mesirov JP, Golub TR, Root DE, Hahn WC. PMID: 25984343; PMCID: PMC4432652.
      View in: PubMed   Mentions: 222     Fields:    Translation:HumansCells
    63. Joint modeling and registration of cell populations in cohorts of high-dimensional flow cytometric data. PLoS One. 2014; 9(7):e100334. Pyne S, Lee SX, Wang K, Irish J, Tamayo P, Nazaire MD, Duong T, Ng SK, Hafler D, Levy R, Nolan GP, Mesirov J, McLachlan GJ. PMID: 24983991; PMCID: PMC4077578.
      View in: PubMed   Mentions: 10     Fields:    Translation:Humans
    64. Cytoscape: the network visualization tool for GenomeSpace workflows. F1000Res. 2014; 3:151. Demchak B, Hull T, Reich M, Liefeld T, Smoot M, Ideker T, Mesirov JP. PMID: 25165537; PMCID: PMC4133763.
      View in: PubMed   Mentions: 103     Fields:    
    65. A melanoma cell state distinction influences sensitivity to MAPK pathway inhibitors. Cancer Discov. 2014 Jul; 4(7):816-27. Konieczkowski DJ, Johannessen CM, Abudayyeh O, Kim JW, Cooper ZA, Piris A, Frederick DT, Barzily-Rokni M, Straussman R, Haq R, Fisher DE, Mesirov JP, Hahn WC, Flaherty KT, Wargo JA, Tamayo P, Garraway LA. PMID: 24771846; PMCID: PMC4154497.
      View in: PubMed   Mentions: 281     Fields:    Translation:HumansCells
    66. Molecular adaptations of striatal spiny projection neurons during levodopa-induced dyskinesia. Proc Natl Acad Sci U S A. 2014 Mar 25; 111(12):4578-83. Heiman M, Heilbut A, Francardo V, Kulicke R, Fenster RJ, Kolaczyk ED, Mesirov JP, Surmeier DJ, Cenci MA, Greengard P. PMID: 24599591; PMCID: PMC3970487.
      View in: PubMed   Mentions: 56     Fields:    Translation:Animals
    67. Inhibition of KRAS-driven tumorigenicity by interruption of an autocrine cytokine circuit. Cancer Discov. 2014 Apr; 4(4):452-65. Zhu Z, Aref AR, Cohoon TJ, Barbie TU, Imamura Y, Yang S, Moody SE, Shen RR, Schinzel AC, Thai TC, Reibel JB, Tamayo P, Godfrey JT, Qian ZR, Page AN, Maciag K, Chan EM, Silkworth W, Labowsky MT, Rozhansky L, Mesirov JP, Gillanders WE, Ogino S, Hacohen N, Gaudet S, Eck MJ, Engelman JA, Corcoran RB, Wong KK, Hahn WC, Barbie DA. PMID: 24444711; PMCID: PMC3980023.
      View in: PubMed   Mentions: 115     Fields:    Translation:HumansAnimalsCells
    68. Gene signatures related to B-cell proliferation predict influenza vaccine-induced antibody response. Eur J Immunol. 2014 Jan; 44(1):285-95. Tan Y, Tamayo P, Nakaya H, Pulendran B, Mesirov JP, Haining WN. PMID: 24136404; PMCID: PMC3973429.
      View in: PubMed   Mentions: 42     Fields:    Translation:HumansCellsPHPublic Health
    69. Compression of structured high-throughput sequencing data. PLoS One. 2013; 8(11):e79871. Campagne F, Dorff KC, Chambwe N, Robinson JT, Mesirov JP. PMID: 24260313; PMCID: PMC3832420.
      View in: PubMed   Mentions: 14     Fields:    
    70. Criteria for the use of omics-based predictors in clinical trials. Nature. 2013 Oct 17; 502(7471):317-20. McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA. PMID: 24132288; PMCID: PMC4180668.
      View in: PubMed   Mentions: 103     Fields:    Translation:Humans
    71. Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration. BMC Med. 2013 Oct 17; 11:220. McShane LM, Cavenagh MM, Lively TG, Eberhard DA, Bigbee WL, Williams PM, Mesirov JP, Polley MY, Kim KY, Tricoli JV, Taylor JM, Shuman DJ, Simon RM, Doroshow JH, Conley BA. PMID: 24228635; PMCID: PMC3852338.
      View in: PubMed   Mentions: 54     Fields:    Translation:Humans
    72. Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Res. 2013 Oct 15; 73(20):6289-98. Abazeed ME, Adams DJ, Hurov KE, Tamayo P, Creighton CJ, Sonkin D, Giacomelli AO, Du C, Fries DF, Wong KK, Mesirov JP, Loeffler JS, Schreiber SL, Hammerman PS, Meyerson M. PMID: 23980093; PMCID: PMC3856255.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansCells
    73. GenePattern flow cytometry suite. Source Code Biol Med. 2013 Jul 03; 8(1):14. Spidlen J, Barsky A, Breuer K, Carr P, Nazaire MD, Hill BA, Qian Y, Liefeld T, Reich M, Mesirov JP, Wilkinson P, Scheuermann RH, Sekaly RP, Brinkman RR. PMID: 23822732; PMCID: PMC3717030.
      View in: PubMed   Mentions: 9  
    74. Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discov. 2013 Sep; 3(9):1044-57. Hagerstrand D, Tong A, Schumacher SE, Ilic N, Shen RR, Cheung HW, Vazquez F, Shrestha Y, Kim SY, Giacomelli AO, Rosenbluh J, Schinzel AC, Spardy NA, Barbie DA, Mermel CH, Weir BA, Garraway LA, Tamayo P, Mesirov JP, Beroukhim R, Hahn WC. PMID: 23764425; PMCID: PMC3770815.
      View in: PubMed   Mentions: 43     Fields:    Translation:HumansCells
    75. Reproducibility: In praise of open research measures. Nature. 2013 Jun 13; 498(7453):170. Kolker E, Altintas I, Bourne P, Faris J, Fox G, Frishman D, Geraci C, Hancock W, Lin B, Lancet D, Lisitsa A, Knight R, Martens L, Mesirov J, Özdemir V, Schultes E, Smith T, Snyder M, Srivastava S, Toppo S, Wilmes P. PMID: 23765483.
      View in: PubMed   Mentions: 3     Fields:    
    76. Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. PLoS One. 2013; 8(2):e54873. Raeder MB, Birkeland E, Trovik J, Krakstad C, Shehata S, Schumacher S, Zack TI, Krohn A, Werner HM, Moody SE, Wik E, Stefansson IM, Holst F, Oyan AM, Tamayo P, Mesirov JP, Kalland KH, Akslen LA, Simon R, Beroukhim R, Salvesen HB. PMID: 23393560; PMCID: PMC3564856.
      View in: PubMed   Mentions: 44     Fields:    Translation:HumansCells
    77. ATARiS: computational quantification of gene suppression phenotypes from multisample RNAi screens. Genome Res. 2013 Apr; 23(4):665-78. Shao DD, Tsherniak A, Gopal S, Weir BA, Tamayo P, Stransky N, Schumacher SE, Zack TI, Beroukhim R, Garraway LA, Margolin AA, Root DE, Hahn WC, Mesirov JP. PMID: 23269662; PMCID: PMC3613583.
      View in: PubMed   Mentions: 82     Fields:    Translation:HumansAnimals
    78. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. J Clin Invest. 2013 Jan; 123(1):517-25. Verhaak RG, Tamayo P, Yang JY, Hubbard D, Zhang H, Creighton CJ, Fereday S, Lawrence M, Carter SL, Mermel CH, Kostic AD, Etemadmoghadam D, Saksena G, Cibulskis K, Duraisamy S, Levanon K, Sougnez C, Tsherniak A, Gomez S, Onofrio R, Gabriel S, Chin L, Zhang N, Spellman PT, Zhang Y, Akbani R, Hoadley KA, Kahn A, Köbel M, Huntsman D, Soslow RA, Defazio A, Birrer MJ, Gray JW, Weinstein JN, Bowtell DD, Drapkin R, Mesirov JP, Getz G, Levine DA, Meyerson M, Cancer Genome Atlas Research Network. PMID: 23257362; PMCID: PMC3533304.
      View in: PubMed   Mentions: 319     Fields:    Translation:HumansCTClinical Trials
    79. β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell. 2012 Dec 21; 151(7):1457-73. Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC. PMID: 23245941; PMCID: PMC3530160.
      View in: PubMed   Mentions: 420     Fields:    Translation:HumansAnimalsCells
    80. The limitations of simple gene set enrichment analysis assuming gene independence. Stat Methods Med Res. 2016 Feb; 25(1):472-87. Tamayo P, Steinhardt G, Liberzon A, Mesirov JP. PMID: 23070592; PMCID: PMC3758419.
      View in: PubMed   Mentions: 60     Fields:    Translation:Humans
    81. An RNA profile identifies two subsets of multiple sclerosis patients differing in disease activity. Sci Transl Med. 2012 Sep 26; 4(153):153ra131. Ottoboni L, Keenan BT, Tamayo P, Kuchroo M, Mesirov JP, Buckle GJ, Khoury SJ, Hafler DA, Weiner HL, De Jager PL. PMID: 23019656; PMCID: PMC3753678.
      View in: PubMed   Mentions: 30     Fields:    Translation:HumansCells
    82. Cancer vulnerabilities unveiled by genomic loss. Cell. 2012 Aug 17; 150(4):842-54. Nijhawan D, Zack TI, Ren Y, Strickland MR, Lamothe R, Schumacher SE, Tsherniak A, Besche HC, Rosenbluh J, Shehata S, Cowley GS, Weir BA, Goldberg AL, Mesirov JP, Root DE, Bhatia SN, Beroukhim R, Hahn WC. PMID: 22901813; PMCID: PMC3429351.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    83. Targeted tumor-penetrating siRNA nanocomplexes for credentialing the ovarian cancer oncogene ID4. Sci Transl Med. 2012 Aug 15; 4(147):147ra112. Ren Y, Cheung HW, von Maltzhan G, Agrawal A, Cowley GS, Weir BA, Boehm JS, Tamayo P, Karst AM, Liu JF, Hirsch MS, Mesirov JP, Drapkin R, Root DE, Lo J, Fogal V, Ruoslahti E, Hahn WC, Bhatia SN. PMID: 22896676; PMCID: PMC3633234.
      View in: PubMed   Mentions: 85     Fields:    Translation:HumansAnimalsCells
    84. Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature. 2012 Aug 02; 488(7409):106-10. Pugh TJ, Weeraratne SD, Archer TC, Pomeranz Krummel DA, Auclair D, Bochicchio J, Carneiro MO, Carter SL, Cibulskis K, Erlich RL, Greulich H, Lawrence MS, Lennon NJ, McKenna A, Meldrim J, Ramos AH, Ross MG, Russ C, Shefler E, Sivachenko A, Sogoloff B, Stojanov P, Tamayo P, Mesirov JP, Amani V, Teider N, Sengupta S, Francois JP, Northcott PA, Taylor MD, Yu F, Crabtree GR, Kautzman AG, Gabriel SB, Getz G, Jäger N, Jones DT, Lichter P, Pfister SM, Roberts TM, Meyerson M, Pomeroy SL, Cho YJ. PMID: 22820256; PMCID: PMC3413789.
      View in: PubMed   Mentions: 405     Fields:    Translation:HumansCells
    85. Transcriptional profiling of Plasmodium falciparum parasites from patients with severe malaria identifies distinct low vs. high parasitemic clusters. PLoS One. 2012; 7(7):e40739. Milner DA, Pochet N, Krupka M, Williams C, Seydel K, Taylor TE, Van de Peer Y, Regev A, Wirth D, Daily JP, Mesirov JP. PMID: 22815802; PMCID: PMC3399889.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansAnimalsCells
    86. AraPath: a knowledgebase for pathway analysis in Arabidopsis. Bioinformatics. 2012 Sep 01; 28(17):2291-2. Lai L, Liberzon A, Hennessey J, Jiang G, Qi J, Mesirov JP, Ge SX. PMID: 22760305; PMCID: PMC3426845.
      View in: PubMed   Mentions: 13     Fields:    Translation:Animals
    87. MicroSCALE screening reveals genetic modifiers of therapeutic response in melanoma. Sci Signal. 2012 May 15; 5(224):rs4. Wood KC, Konieczkowski DJ, Johannessen CM, Boehm JS, Tamayo P, Botvinnik OB, Mesirov JP, Hahn WC, Root DE, Garraway LA, Sabatini DM. PMID: 22589389; PMCID: PMC3498828.
      View in: PubMed   Mentions: 22     Fields:    Translation:HumansCells
    88. Prediction of response to therapy with ezatiostat in lower risk myelodysplastic syndrome. J Hematol Oncol. 2012 May 06; 5:20. Galili N, Tamayo P, Botvinnik OB, Mesirov JP, Brooks MR, Brown G, Raza A. PMID: 22559819; PMCID: PMC3407785.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
    89. Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration. Brief Bioinform. 2013 Mar; 14(2):178-92. Thorvaldsdóttir H, Robinson JT, Mesirov JP. PMID: 22517427; PMCID: PMC3603213.
      View in: PubMed   Mentions: 4174     Fields:    Translation:Humans
    90. The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 2012 Mar 28; 483(7391):603-7. Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, Morais P, Meltzer J, Korejwa A, Jané-Valbuena J, Mapa FA, Thibault J, Bric-Furlong E, Raman P, Shipway A, Engels IH, Cheng J, Yu GK, Yu J, Aspesi P, de Silva M, Jagtap K, Jones MD, Wang L, Hatton C, Palescandolo E, Gupta S, Mahan S, Sougnez C, Onofrio RC, Liefeld T, MacConaill L, Winckler W, Reich M, Li N, Mesirov JP, Gabriel SB, Getz G, Ardlie K, Chan V, Myer VE, Weber BL, Porter J, Warmuth M, Finan P, Harris JL, Meyerson M, Golub TR, Morrissey MP, Sellers WR, Schlegel R, Garraway LA. PMID: 22460905; PMCID: PMC3320027.
      View in: PubMed   Mentions: 3944     Fields:    Translation:HumansCells
    91. Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer. Proc Natl Acad Sci U S A. 2011 Jul 26; 108(30):12372-7. Cheung HW, Cowley GS, Weir BA, Boehm JS, Rusin S, Scott JA, East A, Ali LD, Lizotte PH, Wong TC, Jiang G, Hsiao J, Mermel CH, Getz G, Barretina J, Gopal S, Tamayo P, Gould J, Tsherniak A, Stransky N, Luo B, Ren Y, Drapkin R, Bhatia SN, Mesirov JP, Garraway LA, Meyerson M, Lander ES, Root DE, Hahn WC. PMID: 21746896; PMCID: PMC3145679.
      View in: PubMed   Mentions: 253     Fields:    Translation:HumansCells
    92. Molecular signatures database (MSigDB) 3.0. Bioinformatics. 2011 Jun 15; 27(12):1739-40. Liberzon A, Subramanian A, Pinchback R, Thorvaldsdóttir H, Tamayo P, Mesirov JP. PMID: 21546393; PMCID: PMC3106198.
      View in: PubMed   Mentions: 2834     Fields:    
    93. Predicting relapse in patients with medulloblastoma by integrating evidence from clinical and genomic features. J Clin Oncol. 2011 Apr 10; 29(11):1415-23. Tamayo P, Cho YJ, Tsherniak A, Greulich H, Ambrogio L, Schouten-van Meeteren N, Zhou T, Buxton A, Kool M, Meyerson M, Pomeroy SL, Mesirov JP. PMID: 21357789; PMCID: PMC3082982.
      View in: PubMed   Mentions: 44     Fields:    Translation:Humans
    94. Integrative genomics viewer. Nat Biotechnol. 2011 Jan; 29(1):24-6. Robinson JT, Thorvaldsdóttir H, Winckler W, Guttman M, Lander ES, Getz G, Mesirov JP. PMID: 21221095; PMCID: PMC3346182.
      View in: PubMed   Mentions: 6806     Fields:    Translation:Humans
    95. Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol. 2011 Apr 10; 29(11):1424-30. Cho YJ, Tsherniak A, Tamayo P, Santagata S, Ligon A, Greulich H, Berhoukim R, Amani V, Goumnerova L, Eberhart CG, Lau CC, Olson JM, Gilbertson RJ, Gajjar A, Delattre O, Kool M, Ligon K, Meyerson M, Mesirov JP, Pomeroy SL. PMID: 21098324; PMCID: PMC3082983.
      View in: PubMed   Mentions: 365     Fields:    Translation:Humans
    96. Loss of the tumor suppressor Snf5 leads to aberrant activation of the Hedgehog-Gli pathway. Nat Med. 2010 Dec; 16(12):1429-33. Jagani Z, Mora-Blanco EL, Sansam CG, McKenna ES, Wilson B, Chen D, Klekota J, Tamayo P, Nguyen PT, Tolstorukov M, Park PJ, Cho YJ, Hsiao K, Buonamici S, Pomeroy SL, Mesirov JP, Ruffner H, Bouwmeester T, Luchansky SJ, Murtie J, Kelleher JF, Warmuth M, Sellers WR, Roberts CW, Dorsch M. PMID: 21076395; PMCID: PMC3859448.
      View in: PubMed   Mentions: 132     Fields:    Translation:HumansAnimalsCells
    97. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3698-703. Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, Brugge JS, Ramaswamy S. PMID: 20133671; PMCID: PMC2840447.
      View in: PubMed   Mentions: 107     Fields:    Translation:Humans
    98. Computer science. Accessible reproducible research. Science. 2010 Jan 22; 327(5964):415-6. Mesirov JP. PMID: 20093459; PMCID: PMC3878063.
      View in: PubMed   Mentions: 64     Fields:    
    99. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell. 2010 Jan 19; 17(1):98-110. Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O'Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN, Cancer Genome Atlas Research Network. PMID: 20129251; PMCID: PMC2818769.
      View in: PubMed   Mentions: 3863     Fields:    Translation:Humans
    100. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1. Nature. 2009 Nov 05; 462(7269):108-12. Barbie DA, Tamayo P, Boehm JS, Kim SY, Moody SE, Dunn IF, Schinzel AC, Sandy P, Meylan E, Scholl C, Fröhling S, Chan EM, Sos ML, Michel K, Mermel C, Silver SJ, Weir BA, Reiling JH, Sheng Q, Gupta PB, Wadlow RC, Le H, Hoersch S, Wittner BS, Ramaswamy S, Livingston DM, Sabatini DM, Meyerson M, Thomas RK, Lander ES, Mesirov JP, Root DE, Gilliland DG, Jacks T, Hahn WC. PMID: 19847166; PMCID: PMC2783335.
      View in: PubMed   Mentions: 1749     Fields:    Translation:HumansCells
    101. In vivo profiles in malaria are consistent with a novel physiological state. Proc Natl Acad Sci U S A. 2009 Jul 07; 106(27):E70; author reply E71-2. Wirth D, Daily J, Winzeler E, Mesirov JP, Regev A. PMID: 19570993; PMCID: PMC2708753.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    102. Automated high-dimensional flow cytometric data analysis. Proc Natl Acad Sci U S A. 2009 May 26; 106(21):8519-24. Pyne S, Hu X, Wang K, Rossin E, Lin TI, Maier LM, Baecher-Allan C, McLachlan GJ, Tamayo P, Hafler DA, De Jager PL, Mesirov JP. PMID: 19443687; PMCID: PMC2682540.
      View in: PubMed   Mentions: 113     Fields:    Translation:Cells
    103. Prediction of high-responding peptides for targeted protein assays by mass spectrometry. Nat Biotechnol. 2009 Feb; 27(2):190-8. Fusaro VA, Mani DR, Mesirov JP, Carr SA. PMID: 19169245; PMCID: PMC2753399.
      View in: PubMed   Mentions: 114     Fields:    Translation:HumansCells
    104. ISMB 2008 Toronto. PLoS Comput Biol. 2008 Jun 27; 4(6):e1000094. Linial M, Mesirov JP, Morrison McKay BJ, Rost B. PMID: 18584023; PMCID: PMC2427177.
      View in: PubMed   Mentions:    Fields:    
    105. Cytometric profiling in multiple sclerosis uncovers patient population structure and a reduction of CD8low cells. Brain. 2008 Jul; 131(Pt 7):1701-11. De Jager PL, Rossin E, Pyne S, Tamayo P, Ottoboni L, Viglietta V, Weiner M, Soler D, Izmailova E, Faron-Yowe L, O'Brien C, Freeman S, Granados S, Parker A, Roubenoff R, Mesirov JP, Khoury SJ, Hafler DA, Weiner HL. PMID: 18567923; PMCID: PMC2730047.
      View in: PubMed   Mentions: 32     Fields:    Translation:HumansCells
    106. Using GenePattern for gene expression analysis. Curr Protoc Bioinformatics. 2008 Jun; Chapter 7:7.12.1-7.12.39. Kuehn H, Liberzon A, Reich M, Mesirov JP. PMID: 18551415; PMCID: PMC3893799.
      View in: PubMed   Mentions: 49     Fields:    
    107. Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells. Cancer Res. 2008 Jun 01; 68(11):4331-9. Mishra PJ, Mishra PJ, Humeniuk R, Medina DJ, Alexe G, Mesirov JP, Ganesan S, Glod JW, Banerjee D. PMID: 18519693; PMCID: PMC2725025.
      View in: PubMed   Mentions: 431     Fields:    Translation:HumansAnimalsCells
    108. Gene expression changes in an animal melanoma model correlate with aggressiveness of human melanoma metastases. Mol Cancer Res. 2008 May; 6(5):760-9. Xu L, Shen SS, Hoshida Y, Subramanian A, Ross K, Brunet JP, Wagner SN, Ramaswamy S, Mesirov JP, Hynes RO. PMID: 18505921; PMCID: PMC2756991.
      View in: PubMed   Mentions: 137     Fields:    Translation:HumansAnimalsCells
    109. Distinct physiological states of Plasmodium falciparum in malaria-infected patients. Nature. 2007 Dec 13; 450(7172):1091-5. Daily JP, Scanfeld D, Pochet N, Le Roch K, Plouffe D, Kamal M, Sarr O, Mboup S, Ndir O, Wypij D, Levasseur K, Thomas E, Tamayo P, Dong C, Zhou Y, Lander ES, Ndiaye D, Wirth D, Winzeler EA, Mesirov JP, Regev A. PMID: 18046333.
      View in: PubMed   Mentions: 117     Fields:    Translation:HumansAnimalsCells
    110. Subclass mapping: identifying common subtypes in independent disease data sets. PLoS One. 2007 Nov 21; 2(11):e1195. Hoshida Y, Brunet JP, Tamayo P, Golub TR, Mesirov JP. PMID: 18030330; PMCID: PMC2065909.
      View in: PubMed   Mentions: 278     Fields:    Translation:Humans
    111. High expression of lymphocyte-associated genes in node-negative HER2+ breast cancers correlates with lower recurrence rates. Cancer Res. 2007 Nov 15; 67(22):10669-76. Alexe G, Dalgin GS, Scanfeld D, Tamayo P, Mesirov JP, DeLisi C, Harris L, Barnard N, Martel M, Levine AJ, Ganesan S, Bhanot G. PMID: 18006808.
      View in: PubMed   Mentions: 102     Fields:    Translation:HumansCells
    112. Efficient mapping of mendelian traits in dogs through genome-wide association. Nat Genet. 2007 Nov; 39(11):1321-8. Karlsson EK, Baranowska I, Wade CM, Salmon Hillbertz NH, Zody MC, Anderson N, Biagi TM, Patterson N, Pielberg GR, Kulbokas EJ, Comstock KE, Keller ET, Mesirov JP, von Euler H, Kämpe O, Hedhammar A, Lander ES, Andersson G, Andersson L, Lindblad-Toh K. PMID: 17906626.
      View in: PubMed   Mentions: 270     Fields:    Translation:AnimalsCells
    113. Comment on "The consensus coding sequences of human breast and colorectal cancers". Science. 2007 Sep 14; 317(5844):1500. Getz G, Höfling H, Mesirov JP, Golub TR, Meyerson M, Tibshirani R, Lander ES. PMID: 17872428.
      View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
    114. Portraits of breast cancer progression. BMC Bioinformatics. 2007 Aug 06; 8:291. Dalgin GS, Alexe G, Scanfeld D, Tamayo P, Mesirov JP, Ganesan S, DeLisi C, Bhanot G. PMID: 17683614; PMCID: PMC1978212.
      View in: PubMed   Mentions: 18     Fields:    Translation:Humans
    115. GSEA-P: a desktop application for Gene Set Enrichment Analysis. Bioinformatics. 2007 Dec 01; 23(23):3251-3. Subramanian A, Kuehn H, Gould J, Tamayo P, Mesirov JP. PMID: 17644558.
      View in: PubMed   Mentions: 792     Fields:    Translation:Cells
    116. Metagene projection for cross-platform, cross-species characterization of global transcriptional states. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):5959-64. Tamayo P, Scanfeld D, Ebert BL, Gillette MA, Roberts CW, Mesirov JP. PMID: 17389406; PMCID: PMC1838404.
      View in: PubMed   Mentions: 72     Fields:    Translation:HumansAnimalsCells
    117. Breast cancer stratification from analysis of micro-array data of micro-dissected specimens. Genome Inform. 2007; 18:130-40. Alexe G, Dalgin GS, Scanfeld D, Tamayo P, Mesirov JP, Ganesan S, Delisi C, Bhanot G. PMID: 18546481.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    118. Comparative gene marker selection suite. Bioinformatics. 2006 Aug 01; 22(15):1924-5. Gould J, Getz G, Monti S, Reich M, Mesirov JP. PMID: 16709585.
      View in: PubMed   Mentions: 81     Fields:    
    119. Combo: a whole genome comparative browser. Bioinformatics. 2006 Jul 15; 22(14):1782-3. Engels R, Yu T, Burge C, Mesirov JP, DeCaprio D, Galagan JE. PMID: 16709588.
      View in: PubMed   Mentions: 25     Fields:    Translation:Cells
    120. GenePattern 2.0. Nat Genet. 2006 May; 38(5):500-1. Reich M, Liefeld T, Gould J, Lerner J, Tamayo P, Mesirov JP. PMID: 16642009.
      View in: PubMed   Mentions: 1202     Fields:    
    121. Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation. Proc Natl Acad Sci U S A. 2005 Dec 06; 102(49):17745-50. Isakoff MS, Sansam CG, Tamayo P, Subramanian A, Evans JA, Fillmore CM, Wang X, Biegel JA, Pomeroy SL, Mesirov JP, Roberts CW. PMID: 16301525; PMCID: PMC1308926.
      View in: PubMed   Mentions: 105     Fields:    Translation:HumansAnimalsCells
    122. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci U S A. 2005 Oct 25; 102(43):15545-50. Subramanian A, Tamayo P, Mootha VK, Mukherjee S, Ebert BL, Gillette MA, Paulovich A, Pomeroy SL, Golub TR, Lander ES, Mesirov JP. PMID: 16199517; PMCID: PMC1239896.
      View in: PubMed   Mentions: 24188     Fields:    Translation:HumansCells
    123. Assembly of polymorphic genomes: algorithms and application to Ciona savignyi. Genome Res. 2005 Aug; 15(8):1127-35. Vinson JP, Jaffe DB, O'Neill K, Karlsson EK, Stange-Thomann N, Anderson S, Mesirov JP, Satoh N, Satou Y, Nusbaum C, Birren B, Galagan JE, Lander ES. PMID: 16077012; PMCID: PMC1182225.
      View in: PubMed   Mentions: 82     Fields:    Translation:AnimalsCells
    124. GeneCruiser: a web service for the annotation of microarray data. Bioinformatics. 2005 Sep 15; 21(18):3681-2. Liefeld T, Reich M, Gould J, Zhang P, Tamayo P, Mesirov JP. PMID: 16030072.
      View in: PubMed   Mentions: 13     Fields:    Translation:HumansAnimals
    125. An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis. Nat Genet. 2005 Jan; 37(1):48-55. Sweet-Cordero A, Mukherjee S, Subramanian A, You H, Roix JJ, Ladd-Acosta C, Mesirov J, Golub TR, Jacks T. PMID: 15608639.
      View in: PubMed   Mentions: 201     Fields:    Translation:Animals
    126. Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype. Nature. 2004 Oct 21; 431(7011):946-57. Jaillon O, Aury JM, Brunet F, Petit JL, Stange-Thomann N, Mauceli E, Bouneau L, Fischer C, Ozouf-Costaz C, Bernot A, Nicaud S, Jaffe D, Fisher S, Lutfalla G, Dossat C, Segurens B, Dasilva C, Salanoubat M, Levy M, Boudet N, Castellano S, Anthouard V, Jubin C, Castelli V, Katinka M, Vacherie B, Biémont C, Skalli Z, Cattolico L, Poulain J, De Berardinis V, Cruaud C, Duprat S, Brottier P, Coutanceau JP, Gouzy J, Parra G, Lardier G, Chapple C, McKernan KJ, McEwan P, Bosak S, Kellis M, Volff JN, Guigó R, Zody MC, Mesirov J, Lindblad-Toh K, Birren B, Nusbaum C, Kahn D, Robinson-Rechavi M, Laudet V, Schachter V, Quétier F, Saurin W, Scarpelli C, Wincker P, Lander ES, Weissenbach J, Roest Crollius H. PMID: 15496914.
      View in: PubMed   Mentions: 747     Fields:    Translation:HumansAnimalsCells
    127. Improving genome annotations using phylogenetic profile anomaly detection. Bioinformatics. 2005 Feb 15; 21(4):464-70. Mikkelsen TS, Galagan JE, Mesirov JP. PMID: 15374867.
      View in: PubMed   Mentions: 9     Fields:    
    128. Metagenes and molecular pattern discovery using matrix factorization. Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12):4164-9. Brunet JP, Tamayo P, Golub TR, Mesirov JP. PMID: 15016911; PMCID: PMC384712.
      View in: PubMed   Mentions: 691     Fields:    
    129. GeneCluster 2.0: an advanced toolset for bioarray analysis. Bioinformatics. 2004 Jul 22; 20(11):1797-8. Reich M, Ohm K, Angelo M, Tamayo P, Mesirov JP. PMID: 14988123.
      View in: PubMed   Mentions: 44     Fields:    
    130. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet. 2003 Jul; 34(3):267-73. Mootha VK, Lindgren CM, Eriksson KF, Subramanian A, Sihag S, Lehar J, Puigserver P, Carlsson E, Ridderstråle M, Laurila E, Houstis N, Daly MJ, Patterson N, Mesirov JP, Golub TR, Tamayo P, Spiegelman B, Lander ES, Hirschhorn JN, Altshuler D, Groop LC. PMID: 12808457.
      View in: PubMed   Mentions: 4666     Fields:    Translation:HumansAnimalsCells
    131. Estimating dataset size requirements for classifying DNA microarray data. J Comput Biol. 2003; 10(2):119-42. Mukherjee S, Tamayo P, Rogers S, Rifkin R, Engle A, Campbell C, Golub TR, Mesirov JP. PMID: 12804087.
      View in: PubMed   Mentions: 67     Fields:    Translation:Humans
    132. Whole-genome sequence assembly for mammalian genomes: Arachne 2. Genome Res. 2003 Jan; 13(1):91-6. Jaffe DB, Butler J, Gnerre S, Mauceli E, Lindblad-Toh K, Mesirov JP, Zody MC, Lander ES. PMID: 12529310; PMCID: PMC430950.
      View in: PubMed   Mentions: 125     Fields:    Translation:HumansAnimals
    133. Initial sequencing and comparative analysis of the mouse genome. Nature. 2002 Dec 05; 420(6915):520-62. Mouse Genome Sequencing Consortium, Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough R, Alexandersson M, An P, Antonarakis SE, Attwood J, Baertsch R, Bailey J, Barlow K, Beck S, Berry E, Birren B, Bloom T, Bork P, Botcherby M, Bray N, Brent MR, Brown DG, Brown SD, Bult C, Burton J, Butler J, Campbell RD, Carninci P, Cawley S, Chiaromonte F, Chinwalla AT, Church DM, Clamp M, Clee C, Collins FS, Cook LL, Copley RR, Coulson A, Couronne O, Cuff J, Curwen V, Cutts T, Daly M, David R, Davies J, Delehaunty KD, Deri J, Dermitzakis ET, Dewey C, Dickens NJ, Diekhans M, Dodge S, Dubchak I, Dunn DM, Eddy SR, Elnitski L, Emes RD, Eswara P, Eyras E, Felsenfeld A, Fewell GA, Flicek P, Foley K, Frankel WN, Fulton LA, Fulton RS, Furey TS, Gage D, Gibbs RA, Glusman G, Gnerre S, Goldman N, Goodstadt L, Grafham D, Graves TA, Green ED, Gregory S, Guigó R, Guyer M, Hardison RC, Haussler D, Hayashizaki Y, Hillier LW, Hinrichs A, Hlavina W, Holzer T, Hsu F, Hua A, Hubbard T, Hunt A, Jackson I, Jaffe DB, Johnson LS, Jones M, Jones TA, Joy A, Kamal M, Karlsson EK, Karolchik D, Kasprzyk A, Kawai J, Keibler E, Kells C, Kent WJ, Kirby A, Kolbe DL, Korf I, Kucherlapati RS, Kulbokas EJ, Kulp D, Landers T, Leger JP, Leonard S, Letunic I, Levine R, Li J, Li M, Lloyd C, Lucas S, Ma B, Maglott DR, Mardis ER, Matthews L, Mauceli E, Mayer JH, McCarthy M, McCombie WR, McLaren S, McLay K, McPherson JD, Meldrim J, Meredith B, Mesirov JP, Miller W, Miner TL, Mongin E, Montgomery KT, Morgan M, Mott R, Mullikin JC, Muzny DM, Nash WE, Nelson JO, Nhan MN, Nicol R, Ning Z, Nusbaum C, O'Connor MJ, Okazaki Y, Oliver K, Overton-Larty E, Pachter L, Parra G, Pepin KH, Peterson J, Pevzner P, Plumb R, Pohl CS, Poliakov A, Ponce TC, Ponting CP, Potter S, Quail M, Reymond A, Roe BA, Roskin KM, Rubin EM, Rust AG, Santos R, Sapojnikov V, Schultz B, Schultz J, Schwartz MS, Schwartz S, Scott C, Seaman S, Searle S, Sharpe T, Sheridan A, Shownkeen R, Sims S, Singer JB, Slater G, Smit A, Smith DR, Spencer B, Stabenau A, Stange-Thomann N, Sugnet C, Suyama M, Tesler G, Thompson J, Torrents D, Trevaskis E, Tromp J, Ucla C, Ureta-Vidal A, Vinson JP, Von Niederhausern AC, Wade CM, Wall M, Weber RJ, Weiss RB, Wendl MC, West AP, Wetterstrand K, Wheeler R, Whelan S, Wierzbowski J, Willey D, Williams S, Wilson RK, Winter E, Worley KC, Wyman D, Yang S, Yang SP, Zdobnov EM, Zody MC, Lander ES. PMID: 12466850.
      View in: PubMed   Mentions: 2923     Fields:    Translation:HumansAnimalsCells
    134. Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature. 2002 Jan 24; 415(6870):436-42. Pomeroy SL, Tamayo P, Gaasenbeek M, Sturla LM, Angelo M, McLaughlin ME, Kim JY, Goumnerova LC, Black PM, Lau C, Allen JC, Zagzag D, Olson JM, Curran T, Wetmore C, Biegel JA, Poggio T, Mukherjee S, Rifkin R, Califano A, Stolovitzky G, Louis DN, Mesirov JP, Lander ES, Golub TR. PMID: 11807556.
      View in: PubMed   Mentions: 546     Fields:    Translation:Humans
    135. Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning. Nat Med. 2002 Jan; 8(1):68-74. Shipp MA, Ross KN, Tamayo P, Weng AP, Kutok JL, Aguiar RC, Gaasenbeek M, Angelo M, Reich M, Pinkus GS, Ray TS, Koval MA, Last KW, Norton A, Lister TA, Mesirov J, Neuberg DS, Lander ES, Aster JC, Golub TR. PMID: 11786909.
      View in: PubMed   Mentions: 519     Fields:    Translation:HumansCTClinical Trials
    136. ARACHNE: a whole-genome shotgun assembler. Genome Res. 2002 Jan; 12(1):177-89. Batzoglou S, Jaffe DB, Stanley K, Butler J, Gnerre S, Mauceli E, Berger B, Mesirov JP, Lander ES. PMID: 11779843; PMCID: PMC155255.
      View in: PubMed   Mentions: 174     Fields:    Translation:HumansAnimalsCells
    137. Multiclass cancer diagnosis using tumor gene expression signatures. Proc Natl Acad Sci U S A. 2001 Dec 18; 98(26):15149-54. Ramaswamy S, Tamayo P, Rifkin R, Mukherjee S, Yeang CH, Angelo M, Ladd C, Reich M, Latulippe E, Mesirov JP, Poggio T, Gerald W, Loda M, Lander ES, Golub TR. PMID: 11742071; PMCID: PMC64998.
      View in: PubMed   Mentions: 481     Fields:    Translation:Humans
    138. Chemosensitivity prediction by transcriptional profiling. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10787-92. Staunton JE, Slonim DK, Coller HA, Tamayo P, Angelo MJ, Park J, Scherf U, Lee JK, Reinhold WO, Weinstein JN, Mesirov JP, Lander ES, Golub TR. PMID: 11553813; PMCID: PMC58553.
      View in: PubMed   Mentions: 192     Fields:    Translation:HumansCells
    139. Initial sequencing and analysis of the human genome. Nature. 2001 Feb 15; 409(6822):860-921. Lander ES, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle M, FitzHugh W, Funke R, Gage D, Harris K, Heaford A, Howland J, Kann L, Lehoczky J, LeVine R, McEwan P, McKernan K, Meldrim J, Mesirov JP, Miranda C, Morris W, Naylor J, Raymond C, Rosetti M, Santos R, Sheridan A, Sougnez C, Stange-Thomann Y, Stojanovic N, Subramanian A, Wyman D, Rogers J, Sulston J, Ainscough R, Beck S, Bentley D, Burton J, Clee C, Carter N, Coulson A, Deadman R, Deloukas P, Dunham A, Dunham I, Durbin R, French L, Grafham D, Gregory S, Hubbard T, Humphray S, Hunt A, Jones M, Lloyd C, McMurray A, Matthews L, Mercer S, Milne S, Mullikin JC, Mungall A, Plumb R, Ross M, Shownkeen R, Sims S, Waterston RH, Wilson RK, Hillier LW, McPherson JD, Marra MA, Mardis ER, Fulton LA, Chinwalla AT, Pepin KH, Gish WR, Chissoe SL, Wendl MC, Delehaunty KD, Miner TL, Delehaunty A, Kramer JB, Cook LL, Fulton RS, Johnson DL, Minx PJ, Clifton SW, Hawkins T, Branscomb E, Predki P, Richardson P, Wenning S, Slezak T, Doggett N, Cheng JF, Olsen A, Lucas S, Elkin C, Uberbacher E, Frazier M, Gibbs RA, Muzny DM, Scherer SE, Bouck JB, Sodergren EJ, Worley KC, Rives CM, Gorrell JH, Metzker ML, Naylor SL, Kucherlapati RS, Nelson DL, Weinstock GM, Sakaki Y, Fujiyama A, Hattori M, Yada T, Toyoda A, Itoh T, Kawagoe C, Watanabe H, Totoki Y, Taylor T, Weissenbach J, Heilig R, Saurin W, Artiguenave F, Brottier P, Bruls T, Pelletier E, Robert C, Wincker P, Smith DR, Doucette-Stamm L, Rubenfield M, Weinstock K, Lee HM, Dubois J, Rosenthal A, Platzer M, Nyakatura G, Taudien S, Rump A, Yang H, Yu J, Wang J, Huang G, Gu J, Hood L, Rowen L, Madan A, Qin S, Davis RW, Federspiel NA, Abola AP, Proctor MJ, Myers RM, Schmutz J, Dickson M, Grimwood J, Cox DR, Olson MV, Kaul R, Raymond C, Shimizu N, Kawasaki K, Minoshima S, Evans GA, Athanasiou M, Schultz R, Roe BA, Chen F, Pan H, Ramser J, Lehrach H, Reinhardt R, McCombie WR, de la Bastide M, Dedhia N, Blöcker H, Hornischer K, Nordsiek G, Agarwala R, Aravind L, Bailey JA, Bateman A, Batzoglou S, Birney E, Bork P, Brown DG, Burge CB, Cerutti L, Chen HC, Church D, Clamp M, Copley RR, Doerks T, Eddy SR, Eichler EE, Furey TS, Galagan J, Gilbert JG, Harmon C, Hayashizaki Y, Haussler D, Hermjakob H, Hokamp K, Jang W, Johnson LS, Jones TA, Kasif S, Kaspryzk A, Kennedy S, Kent WJ, Kitts P, Koonin EV, Korf I, Kulp D, Lancet D, Lowe TM, McLysaght A, Mikkelsen T, Moran JV, Mulder N, Pollara VJ, Ponting CP, Schuler G, Schultz J, Slater G, Smit AF, Stupka E, Szustakowki J, Thierry-Mieg D, Thierry-Mieg J, Wagner L, Wallis J, Wheeler R, Williams A, Wolf YI, Wolfe KH, Yang SP, Yeh RF, Collins F, Guyer MS, Peterson J, Felsenfeld A, Wetterstrand KA, Patrinos A, Morgan MJ, de Jong P, Catanese JJ, Osoegawa K, Shizuya H, Choi S, Chen YJ, Szustakowki J, International Human Genome Sequencing Consortium. PMID: 11237011.
      View in: PubMed   Mentions: 7641     Fields:    Translation:HumansAnimalsCells
    140. Human and mouse gene structure: comparative analysis and application to exon prediction. Genome Res. 2000 Jul; 10(7):950-8. Batzoglou S, Pachter L, Mesirov JP, Berger B, Lander ES. PMID: 10899144; PMCID: PMC310911.
      View in: PubMed   Mentions: 123     Fields:    Translation:HumansAnimalsCells
    141. Sequencing a genome by walking with clone-end sequences: a mathematical analysis. Genome Res. 1999 Dec; 9(12):1163-74. Batzoglou S, Berger B, Mesirov J, Lander ES. PMID: 10613838.
      View in: PubMed   Mentions: 12     Fields:    Translation:Cells
    142. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science. 1999 Oct 15; 286(5439):531-7. Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP, Coller H, Loh ML, Downing JR, Caligiuri MA, Bloomfield CD, Lander ES. PMID: 10521349.
      View in: PubMed   Mentions: 1983     Fields:    Translation:Humans
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