Cole Ferguson

Title(s)Assistant Professor, Pathology
SchoolVc-health Sciences-schools
Address9500 Gilman Drive #
La Jolla CA 92093
Emailcferguson@ucsd.edu
ORCID ORCID Icon0000000217900086 Additional info
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    Collapse Biography 
    Collapse education and training
    Yale UniversityBA2003
    University of MichiganMD, PhD2013Neuroscience
    Washington University, St. Louis2017Anatomic and Neuropathology
    Washington University, St. Louis2020Molecular neuroscience

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    Regulation of phase separation in neuronal heterochromatin
    NIH R01NS138924Aug 1, 2024 - May 31, 2029
    Role: Principal Investigator
    Recognition and Ubiqutination of neurodevelopmental chromatin regulators
    NIH R21NS139210Jul 5, 2024 - Jun 30, 2026
    Role: Principal Investigator
    Ubiquitin signaling in epigenetic regulation of neuronal development
    NIH K08HD099314Sep 10, 2019 - Aug 31, 2024
    Role: Principal Investigator

    Collapse ORNG Applications 
    Collapse Featured Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway. Cell Rep. 2025 Feb 25; 44(2):115231. Chen H, Ferguson CJ, Mitchell DC, Risch I, Titus A, Paulo JA, Hwang A, Beck LK, Lin TH, Gu W, Song SK, Yuede CM, Yano H, Griffith OL, Griffith M, Gygi SP, Bonni A, Kim AH. PMID: 39862434.
      View in: PubMed   Mentions:    Fields:    
    2. The anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment. Dev Cell. 2023 Dec 04; 58(23):2666-2683.e9. Ledvin L, Gassaway BM, Tawil J, Urso O, Pizzo D, Welsh KA, Bolhuis DL, Fisher D, Bonni A, Gygi SP, Brown NG, Ferguson CJ. PMID: 37875116; PMCID: PMC10872926.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansAnimalsCells
    3. APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain. Mol Cell. 2022 01 06; 82(1):90-105.e13. Ferguson CJ, Urso O, Bodrug T, Gassaway BM, Watson ER, Prabu JR, Lara-Gonzalez P, Martinez-Chacin RC, Wu DY, Brigatti KW, Puffenberger EG, Taylor CM, Haas-Givler B, Jinks RN, Strauss KA, Desai A, Gabel HW, Gygi SP, Schulman BA, Brown NG, Bonni A. PMID: 34942119; PMCID: PMC8741739.
      View in: PubMed   Mentions: 5     Fields:    Translation:HumansAnimalsCells
    4. CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nat Commun. 2021 09 29; 12(1):5702. Reddy NC, Majidi SP, Kong L, Nemera M, Ferguson CJ, Moore M, Goncalves TM, Liu HK, Fitzpatrick JAJ, Zhao G, Yamada T, Bonni A, Gabel HW. PMID: 34588434; PMCID: PMC8481233.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimalsCells
    5. Acute Posterior Multifocal Placoid Pigment Epitheliopathy Complicated by Fatal Cerebral Vasculitis. J Neuroophthalmol. 2019 Jun; 39(2):260-267. Maamari RN, Stunkel L, Kung NH, Ferguson CJ, Tanabe J, Schmidt RE, Dahiya S, Dhand A, Van Stavern GP, Rajagopal R, Harocopos GJ. PMID: 30676416.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    6. Epidermal Growth Factor Receptor Extracellular Domain Mutations in Glioblastoma Present Opportunities for Clinical Imaging and Therapeutic Development. Cancer Cell. 2018 07 09; 34(1):163-177.e7. Binder ZA, Thorne AH, Bakas S, Wileyto EP, Bilello M, Akbari H, Rathore S, Ha SM, Zhang L, Ferguson CJ, Dahiya S, Bi WL, Reardon DA, Idbaih A, Felsberg J, Hentschel B, Weller M, Bagley SJ, Morrissette JJD, Nasrallah MP, Ma J, Zanca C, Scott AM, Orellana L, Davatzikos C, Furnari FB, O'Rourke DM. PMID: 29990498; PMCID: PMC6424337.
      View in: PubMed   Mentions: 89     Fields:    Translation:HumansAnimalsCells
    7. Modulation of synaptic function by VAC14, a protein that regulates the phosphoinositides PI(3,5)P₂ and PI(5)P. EMBO J. 2012 Aug 15; 31(16):3442-56. Zhang Y, McCartney AJ, Zolov SN, Ferguson CJ, Meisler MH, Sutton MA, Weisman LS. PMID: 22842785; PMCID: PMC3419932.
      View in: PubMed   Mentions: 29     Fields:    Translation:AnimalsCells
    8. Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration. Hum Mol Genet. 2012 Aug 15; 21(16):3525-34. Ferguson CJ, Lenk GM, Jones JM, Grant AE, Winters JJ, Dowling JJ, Giger RJ, Meisler MH. PMID: 22581779; PMCID: PMC3406753.
      View in: PubMed   Mentions: 35     Fields:    Translation:AnimalsCells
    9. Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4. J Neurosci. 2011 Nov 30; 31(48):17736-51. Winters JJ, Ferguson CJ, Lenk GM, Giger-Mateeva VI, Shrager P, Meisler MH, Giger RJ. PMID: 22131434; PMCID: PMC3711465.
      View in: PubMed   Mentions: 25     Fields:    Translation:AnimalsCells
    10. Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P₂ phosphatase FIG4. Brain. 2011 Jul; 134(Pt 7):1959-71. Nicholson G, Lenk GM, Reddel SW, Grant AE, Towne CF, Ferguson CJ, Simpson E, Scheuerle A, Yasick M, Hoffman S, Blouin R, Brandt C, Coppola G, Biesecker LG, Batish SD, Meisler MH. PMID: 21705420; PMCID: PMC3122378.
      View in: PubMed   Mentions: 59     Fields:    Translation:Humans
    11. Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J. PLoS Genet. 2011 Jun; 7(6):e1002104. Lenk GM, Ferguson CJ, Chow CY, Jin N, Jones JM, Grant AE, Zolov SN, Winters JJ, Giger RJ, Dowling JJ, Weisman LS, Meisler MH. PMID: 21655088; PMCID: PMC3107197.
      View in: PubMed   Mentions: 63     Fields:    Translation:HumansAnimalsCells
    12. PtdIns(3,5)P2 and autophagy in mouse models of neurodegeneration. Autophagy. 2010 Jan; 6(1):170-1. Ferguson CJ, Lenk GM, Meisler MH. PMID: 20009544; PMCID: PMC2859463.
      View in: PubMed   Mentions: 15     Fields:    Translation:HumansAnimals
    13. Defective autophagy in neurons and astrocytes from mice deficient in PI(3,5)P2. Hum Mol Genet. 2009 Dec 15; 18(24):4868-78. Ferguson CJ, Lenk GM, Meisler MH. PMID: 19793721; PMCID: PMC2778378.
      View in: PubMed   Mentions: 106     Fields:    Translation:HumansAnimalsCells
    14. Hematopoietic stem cell gene therapy: dead or alive? Trends Biotechnol. 2005 Dec; 23(12):589-97. Ferguson C, Larochelle A, Dunbar CE. PMID: 16216357.
      View in: PubMed   Mentions: 8     Fields:    Translation:HumansAnimalsCells
    15. Recurrent retroviral vector integration at the Mds1/Evi1 locus in nonhuman primate hematopoietic cells. Blood. 2005 Oct 01; 106(7):2530-3. Calmels B, Ferguson C, Laukkanen MO, Adler R, Faulhaber M, Kim HJ, Sellers S, Hematti P, Schmidt M, von Kalle C, Akagi K, Donahue RE, Dunbar CE. PMID: 15933056; PMCID: PMC1895268.
      View in: PubMed   Mentions: 66     Fields:    Translation:HumansAnimalsCells
    16. Distinct genomic integration of MLV and SIV vectors in primate hematopoietic stem and progenitor cells. PLoS Biol. 2004 Dec; 2(12):e423. Hematti P, Hong BK, Ferguson C, Adler R, Hanawa H, Sellers S, Holt IE, Eckfeldt CE, Sharma Y, Schmidt M, von Kalle C, Persons DA, Billings EM, Verfaillie CM, Nienhuis AW, Wolfsberg TG, Dunbar CE, Calmels B. PMID: 15550989; PMCID: PMC529319.
      View in: PubMed   Mentions: 122     Fields:    Translation:AnimalsCells
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