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Mark Herzik

TitleAssistant Professor
InstitutionUniversity of California San Diego
DepartmentChemistry and Biochemistry
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Zubcevic L, Herzik MA, Wu M, Borschel WF, Hirschi M, Song AS, Lander GC, Lee SY. Conformational ensemble of the human TRPV3 ion channel. Nat Commun. 2018 11 14; 9(1):4773. PMID: 30429472.
      View in: PubMed
    2. Herzik MA, Fraser JS, Lander GC. A Multi-model Approach to Assessing Local and Global Cryo-EM Map Quality. Structure. 2018 Oct 25. PMID: 30449687.
      View in: PubMed
    3. Yoo J, Wu M, Yin Y, Herzik MA, Lander GC, Lee SY. Cryo-EM structure of a mitochondrial calcium uniporter. Science. 2018 08 03; 361(6401):506-511. PMID: 29954988.
      View in: PubMed
    4. Kurakula K, Koenis DS, Herzik MA, Liu Y, Craft JW, van Loenen PB, Vos M, Tran MK, Versteeg HH, Goumans MTH, Ruf W, de Vries CJM, Sen M. Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity. Haematologica. 2018 Jun; 103(6):1073-1082. PMID: 29545340.
      View in: PubMed
    5. Hirschi M, Herzik MA, Wie J, Suo Y, Borschel WF, Ren D, Lander GC, Lee SY. Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3. Nature. 2017 10 19; 550(7676):411-414. PMID: 29019979.
      View in: PubMed
    6. Herzik MA, Wu M, Lander GC. Achieving better-than-3-Å resolution by single-particle cryo-EM at 200 keV. Nat Methods. 2017 Nov; 14(11):1075-1078. PMID: 28991891.
      View in: PubMed
    7. Guo Y, Suess DLM, Herzik MA, Iavarone AT, Britt RD, Marletta MA. Regulation of nitric oxide signaling by formation of a distal receptor-ligand complex. Nat Chem Biol. 2017 Dec; 13(12):1216-1221. PMID: 28967923.
      View in: PubMed
    8. Rao M, Herzik MA, Iavarone AT, Marletta MA. Nitric Oxide-Induced Conformational Changes Govern H-NOX and Histidine Kinase Interaction and Regulation in Shewanella oneidensis. Biochemistry. 2017 03 07; 56(9):1274-1284. PMID: 28170222.
      View in: PubMed
    9. Zubcevic L, Herzik MA, Chung BC, Liu Z, Lander GC, Lee SY. Cryo-electron microscopy structure of the TRPV2 ion channel. Nat Struct Mol Biol. 2016 Feb; 23(2):180-186. PMID: 26779611; PMCID: PMC4876856.
    10. Dambacher CM, Worden EJ, Herzik MA, Martin A, Lander GC. Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition. Elife. 2016 Jan 08; 5:e13027. PMID: 26744777; PMCID: PMC4749569.
    11. Herzik MA, Jonnalagadda R, Kuriyan J, Marletta MA. Structural insights into the role of iron-histidine bond cleavage in nitric oxide-induced activation of H-NOX gas sensor proteins. Proc Natl Acad Sci U S A. 2014 Oct 07; 111(40):E4156-64. PMID: 25253889; PMCID: PMC4210026.
    12. Winter MB, Herzik MA, Kuriyan J, Marletta MA. Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain. Proc Natl Acad Sci U S A. 2011 Oct 25; 108(43):E881-9. PMID: 21997213; PMCID: PMC3203760.
    13. Yoon J, Herzik MA, Winter MB, Tran R, Olea C, Marletta MA. Structure and properties of a bis-histidyl ligated globin from Caenorhabditis elegans. Biochemistry. 2010 Jul 13; 49(27):5662-70. PMID: 20518498; PMCID: PMC2903878.
    14. Olea C, Herzik MA, Kuriyan J, Marletta MA. Structural insights into the molecular mechanism of H-NOX activation. Protein Sci. 2010 Apr; 19(4):881-7. PMID: 20162612.
      View in: PubMed
    15. Sen M, Herzik M, Craft JW, Creath AL, Agrawal S, Ruf W, Legge GB. Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. Open Spectrosc J. 2009 Jan 01; 3:58-64. PMID: 20076769.
      View in: PubMed
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