Milton Saier

Title(s)Professor, Molecular Biology
SchoolVc-academic Affairs
Address9500 Gilman Drive #
La Jolla CA 92093
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    Collapse Research 
    Collapse Research Activities and Funding
    Integrative functional mapping of the Escherichia coli membrane interactome
    NIH R01GM109895Sep 5, 2014 - Jul 31, 2018
    Role: Principal Investigator
    TransportPDB: Center for the X-ray Structure Determination of Human Transporters
    NIH U54GM094610Sep 30, 2010 - Jun 30, 2015
    Role: Co-Investigator
    The Transporter Classification Database (TCDB)
    NIH R01GM077402Apr 1, 2006 - Mar 31, 2022
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH P41RR004050May 15, 1997 - Mar 31, 2014
    Role: Co-Investigator
    ATP-Dependent Protein Kinases in Gram-Positive Bacteria
    NIH R01GM055434Dec 1, 1984 - Jun 30, 2006
    Role: Principal Investigator
    ATP-DEPENDENT PROTEIN KINASES IN GRAM-POSITIVE BACTERIA
    NIH R01AI021702Dec 1, 1984 - Nov 30, 1996
    Role: Principal Investigator
    FUNCTION AND CONTROL OF A KIDNEY EPITHELIAL CELL LINE
    NIH R01AM021994Jul 1, 1979 - Mar 31, 1986
    Role: Principal Investigator
    Mechanism of Carbohydrate Transport in Bacteria
    NIH R01GM064368Sep 1, 1977 - Mar 31, 2006
    Role: Principal Investigator
    MECHANISM OF CARBOHYDRATE TRANSPORT IN BACTERIA
    NIH R01AI014176Sep 1, 1977 - Mar 31, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help. to make corrections and additions.
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    Altmetrics Details PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. The Protein Interactome of Glycolysis in Escherichia coli. Proteomes. 2021 Apr 06; 9(2). Chowdhury S, Hepper S, Lodi MK, Saier MH, Uetz P. PMID: 33917325.
      View in: PubMed   Mentions:
    2. Comparative population genomic analyses of transporters within the Asgard archaeal superphylum. PLoS One. 2021; 16(3):e0247806. Russum S, Lam KJK, Wong NA, Iddamsetty V, Hendargo KJ, Wang J, Dubey A, Zhang Y, Medrano-Soto A, Saier MH. PMID: 33770091.
      View in: PubMed   Mentions:    Fields:    
    3. The SARS-Coronavirus Infection Cycle: A Survey of Viral Membrane Proteins, Their Functional Interactions and Pathogenesis. Int J Mol Sci. 2021 Jan 28; 22(3). Wong NA, Saier MH. PMID: 33525632.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansAnimalsCells
    4. The Transporter Classification Database (TCDB): 2021 update. Nucleic Acids Res. 2021 01 08; 49(D1):D461-D467. Saier MH, Reddy VS, Moreno-Hagelsieb G, Hendargo KJ, Zhang Y, Iddamsetty V, Lam KJK, Tian N, Russum S, Wang J, Medrano-Soto A. PMID: 33170213.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    5. Gut Bacteroides species in health and disease. Gut Microbes. 2021 Jan-Dec; 13(1):1-20. Zafar H, Saier MH. PMID: 33535896.
      View in: PubMed   Mentions: 1     Fields:    
    6. Comparative Genomics of the Transport Proteins of Ten Lactobacillus Strains. Genes (Basel). 2020 10 21; 11(10). Zafar H, Saier MH. PMID: 33096690.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    7. Protein-Protein Interactions in the Cytoplasmic Membrane of Escherichia coli: Influence of the Overexpression of Diverse Transporter-Encoding Genes on the Activities of PTS Sugar Uptake Systems. Microb Physiol. 2020; 30(1-6):36-49. Aboulwafa M, Zhang Z, Saier MH. PMID: 32998150.
      View in: PubMed   Mentions:
    8. The Causal Relationship between Eating Animals and Viral Epidemics. Microb Physiol. 2020; 30(1-6):2-8. Reddy BL, Saier MHJ. PMID: 32957108.
      View in: PubMed   Mentions:
    9. Expansion of the Transporter-Opsin-G protein-coupled receptor superfamily with five new protein families. PLoS One. 2020; 15(4):e0231085. Medrano-Soto A, Ghazi F, Hendargo KJ, Moreno-Hagelsieb G, Myers S, Saier MH. PMID: 32320418.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    10. Expansion of the Major Facilitator Superfamily (MFS) to include novel transporters as well as transmembrane-acting enzymes. Biochim Biophys Acta Biomembr. 2020 09 01; 1862(9):183277. Wang SC, Davejan P, Hendargo KJ, Javadi-Razaz I, Chou A, Yee DC, Ghazi F, Lam KJK, Conn AM, Madrigal A, Medrano-Soto A, Saier MH. PMID: 32205149.
      View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
    11. Protein:Protein interactions in the cytoplasmic membrane apparently influencing sugar transport and phosphorylation activities of the e. coli phosphotransferase system. PLoS One. 2019; 14(11):e0219332. Aboulwafa M, Zhang Z, Saier MH. PMID: 31751341.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    12. A Riboflavin Transporter in Bdellovibrio exovorous JSS. J Mol Microbiol Biotechnol. 2019; 29(1-6):27-34. Rodionova IA, Heidari Tajabadi F, Zhang Z, Rodionov DA, Saier MH. PMID: 31509826.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    13. Understanding the Genetic Code. J Bacteriol. 2019 08 01; 201(15). Saier MH. PMID: 31010904.
      View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
    14. Cryo-EM structure of OSCA1.2 from Oryza sativa elucidates the mechanical basis of potential membrane hyperosmolality gating. Proc Natl Acad Sci U S A. 2019 07 09; 116(28):14309-14318. Maity K, Heumann JM, McGrath AP, Kopcho NJ, Hsu PK, Lee CW, Mapes JH, Garza D, Krishnan S, Morgan GP, Hendargo KJ, Klose T, Rees SD, Medrano-Soto A, Saier MH, Piñeros M, Komives EA, Schroeder JI, Chang G, Stowell MHB. PMID: 31227607.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    15. Comparative genomics of the transportome of Ten Treponema species. Microb Pathog. 2019 Jul; 132:87-99. Buyuktimkin B, Zafar H, Saier MH. PMID: 31029716.
      View in: PubMed   Mentions: 6     Fields:    Translation:HumansAnimalsCells
    16. Comparative genomics of transport proteins in seven Bacteroides species. PLoS One. 2018; 13(12):e0208151. Zafar H, Saier MH. PMID: 30517169.
      View in: PubMed   Mentions: 11     Fields:    Translation:HumansCells
    17. The uridylyltransferase GlnD and tRNA modification GTPase MnmE allosterically control Escherichia coli folylpoly-?-glutamate synthase FolC. J Biol Chem. 2018 10 05; 293(40):15725-15732. Rodionova IA, Goodacre N, Do J, Hosseinnia A, Babu M, Uetz P, Saier MH. PMID: 30089654.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    18. Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases. PLoS One. 2018; 13(3):e0192851. Medrano-Soto A, Moreno-Hagelsieb G, McLaughlin D, Ye ZS, Hendargo KJ, Saier MH. PMID: 29579047.
      View in: PubMed   Mentions: 13     Fields:    Translation:Humans
    19. The Nitrogen Regulatory PII Protein (GlnB) and N-Acetylglucosamine 6-Phosphate Epimerase (NanE) Allosterically Activate Glucosamine 6-Phosphate Deaminase (NagB) in Escherichia coli. J Bacteriol. 2018 03 01; 200(5). Rodionova IA, Goodacre N, Babu M, Emili A, Uetz P, Saier MH. PMID: 29229699.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    20. Comparative Analyses of Transport Proteins Encoded within the Genomes of Bdellovibrio bacteriovorus HD100 and Bdellovibrio exovorus JSS. J Mol Microbiol Biotechnol. 2017; 27(6):332-349. Heidari Tajabadi F, Medrano-Soto A, Ahmadzadeh M, Salehi Jouzani G, Saier MH. PMID: 29212086.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    21. Global landscape of cell envelope protein complexes in Escherichia coli. Nat Biotechnol. 2018 01; 36(1):103-112. Babu M, Bundalovic-Torma C, Calmettes C, Phanse S, Zhang Q, Jiang Y, Minic Z, Kim S, Mehla J, Gagarinova A, Rodionova I, Kumar A, Guo H, Kagan O, Pogoutse O, Aoki H, Deineko V, Caufield JH, Holtzapple E, Zhang Z, Vastermark A, Pandya Y, Lai CC, El Bakkouri M, Hooda Y, Shah M, Burnside D, Hooshyar M, Vlasblom J, Rajagopala SV, Golshani A, Wuchty S, F Greenblatt J, Saier M, Uetz P, F Moraes T, Parkinson J, Emili A. PMID: 29176613.
      View in: PubMed   Mentions: 32     Fields:    Translation:Cells
    22. The Membrane Attack Complex/Perforin Superfamily. J Mol Microbiol Biotechnol. 2017; 27(4):252-267. Moreno-Hagelsieb G, Vitug B, Medrano-Soto A, Saier MH. PMID: 29145176.
      View in: PubMed   Mentions: 8     Fields:    Translation:AnimalsCells
    23. Hopping into a hot seat: Role of DNA structural features on IS5-mediated gene activation and inactivation under stress. PLoS One. 2017; 12(6):e0180156. Humayun MZ, Zhang Z, Butcher AM, Moshayedi A, Saier MH. PMID: 28666002.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    24. The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism by directly interacting with multiple enzymes in Escherichia coli. J Biol Chem. 2017 08 25; 292(34):14250-14257. Rodionova IA, Zhang Z, Mehla J, Goodacre N, Babu M, Emili A, Uetz P, Saier MH. PMID: 28634232.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    25. Science, Innovation and the Future of Humanity. J Mol Microbiol Biotechnol. 2017; 27(2):128-132. Saier MH, Trevors JT. PMID: 28448972.
      View in: PubMed   Mentions:    Fields:    Translation:HumansPHPublic Health
    26. Comparative genomic analyses of transport proteins encoded within the red algae Chondrus crispus, Galdieria sulphuraria, and Cyanidioschyzon merolae11. J Phycol. 2017 06; 53(3):503-521. Lee J, Ghosh S, Saier MH. PMID: 28328149.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    27. Environment-directed activation of the Escherichia coliflhDC operon by transposons. Microbiology (Reading). 2017 04; 163(4):554-569. Zhang Z, Kukita C, Humayun MZ, Saier MH. PMID: 28100305.
      View in: PubMed   Mentions:
    28. Comparative genomics of transport proteins in probiotic and pathogenic Escherichia coli and Salmonella enterica strains. Microb Pathog. 2017 Jun; 107:106-115. Do J, Zafar H, Saier MH. PMID: 28344124.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    29. Transposon-mediated directed mutation in bacteria and eukaryotes. Front Biosci (Landmark Ed). 2017 03 01; 22:1458-1468. Saier MH, Kukita C, Zhang Z. PMID: 28199212.
      View in: PubMed   Mentions: 5     Fields:    Translation:AnimalsCells
    30. Difference distance map data of alternative crystal forms of UlaA. Data Brief. 2017 Feb; 10:198-201. Vastermark A, Driker A, Weng J, Li X, Wang J, Saier MH. PMID: 27995154.
      View in: PubMed   Mentions:
    31. Characterization of the Tetraspan Junctional Complex (4JC) superfamily. Biochim Biophys Acta Biomembr. 2017 03; 1859(3):402-414. Chou A, Lee A, Hendargo KJ, Reddy VS, Shlykov MA, Kuppusamykrishnan H, Medrano-Soto A, Saier MH. PMID: 27916633.
      View in: PubMed   Mentions: 2     Fields:    Translation:AnimalsCells
    32. Transposon-mediated activation of the Escherichia coli glpFK operon is inhibited by specific DNA-binding proteins: Implications for stress-induced transposition events. Mutat Res. 2016 Nov - Dec; 793-794:22-31. Zhang Z, Saier MH. PMID: 27810619.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    33. The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism. J Struct Biol. 2016 12; 196(3):496-502. Vastermark A, Driker A, Weng J, Li X, Wang J, Saier MH. PMID: 27720943.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    34. Analysis of 58 Families of Holins Using a Novel Program, PhyST. J Mol Microbiol Biotechnol. 2016; 26(6):381-388. Kuppusamykrishnan H, Chau LM, Moreno-Hagelsieb G, Saier MH. PMID: 27553295.
      View in: PubMed   Mentions: 2     Fields:    
    35. Comparative analyses of transport proteins encoded within the genomes of Leptospira species. Microb Pathog. 2016 Sep; 98:118-31. Buyuktimkin B, Saier MH. PMID: 27296707.
      View in: PubMed   Mentions: 2     Fields:    Translation:HumansCells
    36. Time to Stop Holding the Elevator: A New Piece of the Transport Protein Mechanism Puzzle. Structure. 2016 06 07; 24(6):845-6. Vastermark A, Saier MH. PMID: 27276425.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    37. Transport protein evolution deduced from analysis of sequence, topology and structure. Curr Opin Struct Biol. 2016 06; 38:9-17. Saier MH. PMID: 27270239.
      View in: PubMed   Mentions: 11     Fields:    Translation:AnimalsCells
    38. Properties and Phylogeny of 76 Families of Bacterial and Eukaryotic Organellar Outer Membrane Pore-Forming Proteins. PLoS One. 2016; 11(4):e0152733. Reddy BL, Saier MH. PMID: 27064789.
      View in: PubMed   Mentions: 9     Fields:    Translation:AnimalsCells
    39. The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 04; 44(D1):D372-9. Saier MH, Reddy VS, Tsu BV, Ahmed MS, Li C, Moreno-Hagelsieb G. PMID: 26546518.
      View in: PubMed   Mentions: 209     Fields:    
    40. Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs. PLoS One. 2015; 10(11):e0140569. Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH, Wu W, Nigam SK. PMID: 26536134.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    41. The LysE Superfamily of Transport Proteins Involved in Cell Physiology and Pathogenesis. PLoS One. 2015; 10(10):e0137184. Tsu BV, Saier MH. PMID: 26474485.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    42. Comparative genomic analyses of transport proteins encoded within the genomes of Leptospira species. Microb Pathog. 2015 Nov; 88:52-64. Buyuktimkin B, Saier MH. PMID: 26247102.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    43. Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database (Oxford). 2015; 2015:bav063. Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ, Craik DJ, Finn RD, Gloriam D, Haft DH, Henrissat B, Holliday GL, Isberg V, Kaas Q, Landsman D, Lenfant N, Manning G, Nagano N, Srinivasan N, O'Donovan C, Pruitt KD, Sowdhamini R, Rawlings ND, Saier MH, Sharman JL, Spedding M, Tsirigos KD, Vastermark A, Vriend G. PMID: 26284514.
      View in: PubMed   Mentions: 5     Fields:    Translation:Humans
    44. The Bacterial Phosphotransferase System: New Frontiers 50 Years after Its Discovery. J Mol Microbiol Biotechnol. 2015; 25(2-3):73-8. Saier MH. PMID: 26159069.
      View in: PubMed   Mentions: 14     Fields:    Translation:Cells
    45. Control of Transposon-Mediated Directed Mutation by the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System. J Mol Microbiol Biotechnol. 2015; 25(2-3):226-33. Saier MH, Zhang Z. PMID: 26159081.
      View in: PubMed   Mentions: 3     Fields:    Translation:Cells
    46. Key challenges for the creation and maintenance of specialist protein resources. Proteins. 2015 Jun; 83(6):1005-13. Holliday GL, Bairoch A, Bagos PG, Chatonnet A, Craik DJ, Finn RD, Henrissat B, Landsman D, Manning G, Nagano N, O'Donovan C, Pruitt KD, Rawlings ND, Saier M, Sowdhamini R, Spedding M, Srinivasan N, Vriend G, Babbitt PC, Bateman A. PMID: 25820941.
      View in: PubMed   Mentions: 6     Fields:    
    47. Autism and our intestinal microbiota. J Mol Microbiol Biotechnol. 2015; 25(1):51-5. Reddy BL, Saier MH. PMID: 25792275.
      View in: PubMed   Mentions: 4     Fields:    Translation:Humans
    48. Conserved movement of TMS11 between occluded conformations of LacY and XylE of the major facilitator superfamily suggests a similar hinge-like mechanism. Proteins. 2015 Apr; 83(4):735-45. Västermark Å, Driker A, Li J, Saier MH. PMID: 25586173.
      View in: PubMed   Mentions: 4     Fields:    Translation:Cells
    49. The complexity, challenges and benefits of comparing two transporter classification systems in TCDB and Pfam. Brief Bioinform. 2015 Sep; 16(5):865-72. Chiang Z, Vastermark A, Punta M, Coggill PC, Mistry J, Finn RD, Saier MH. PMID: 25614388.
      View in: PubMed   Mentions: 5     Fields:    
    50. Comparative genomic analysis of integral membrane transport proteins in ciliates. J Eukaryot Microbiol. 2015 Mar-Apr; 62(2):167-87. Kumar U, Saier MH. PMID: 25099884.
      View in: PubMed   Mentions: 1     Fields:    Translation:Animals
    51. Psychobiotics and their involvement in mental health. J Mol Microbiol Biotechnol. 2014; 24(4):211-4. Tang F, Reddy BL, Saier MH. PMID: 25196442.
      View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
    52. Holins in bacteria, eukaryotes, and archaea: multifunctional xenologues with potential biotechnological and biomedical applications. J Bacteriol. 2015 Jan 01; 197(1):7-17. Saier MH, Reddy BL. PMID: 25157079.
      View in: PubMed   Mentions: 42     Fields:    Translation:AnimalsCells
    53. Transposon-mediated directed mutation controlled by DNA binding proteins in Escherichia coli. Front Microbiol. 2014; 5:390. Saier MH, Zhang Z. PMID: 25136335.
      View in: PubMed   Mentions:
    54. Expansion of the APC superfamily of secondary carriers. Proteins. 2014 Oct; 82(10):2797-811. Vastermark A, Wollwage S, Houle ME, Rio R, Saier MH. PMID: 25043943.
      View in: PubMed   Mentions: 31     Fields:    Translation:HumansAnimalsCells
    55. Reliability of nine programs of topological predictions and their application to integral membrane channel and carrier proteins. J Mol Microbiol Biotechnol. 2014; 24(3):161-90. Reddy A, Cho J, Ling S, Reddy V, Shlykov M, Saier MH. PMID: 24992992.
      View in: PubMed   Mentions: 9     Fields:    
    56. Regulation of crp gene expression by the catabolite repressor/activator, Cra, in Escherichia coli. J Mol Microbiol Biotechnol. 2014; 24(3):135-41. Zhang Z, Aboulwafa M, Saier MH. PMID: 24923415.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    57. Establishing homology between mitochondrial calcium uniporters, prokaryotic magnesium channels and chlamydial IncA proteins. Microbiology (Reading). 2014 Aug; 160(Pt 8):1679-1689. Lee A, Vastermark A, Saier MH. PMID: 24869855.
      View in: PubMed   Mentions:
    58. Transport proteins promoting Escherichia coli pathogenesis. Microb Pathog. 2014 Jun-Jul; 71-72:41-55. Tang F, Saier MH. PMID: 24747185.
      View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
    59. Major facilitator superfamily porters, LacY, FucP and XylE of Escherichia coli appear to have evolved positionally dissimilar catalytic residues without rearrangement of 3-TMS repeat units. J Mol Microbiol Biotechnol. 2014; 24(2):82-90. Västermark A, Lunt B, Saier M. PMID: 24603210.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    60. Major Facilitator Superfamily (MFS) evolved without 3-transmembrane segment unit rearrangements. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):E1162-3. Västermark A, Saier MH. PMID: 24567407.
      View in: PubMed   Mentions: 6     Fields:    Translation:Cells
    61. The involvement of transport proteins in transcriptional and metabolic regulation. Curr Opin Microbiol. 2014 Apr; 18:8-15. Västermark A, Saier MH. PMID: 24513656.
      View in: PubMed   Mentions: 19     Fields:    Translation:Cells
    62. Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22; 63(15):1542-55. Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork AJ, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB, International Consortium for Blood Pressure Genome-Wide Association Studies , Schork NJ, Eskin E, Nievergelt CM, Saier MH, O'Connor DT. PMID: 24509276.
      View in: PubMed   Mentions: 7     Fields:    Translation:Humans
    63. Comparative genomics of transport proteins in developmental bacteria: Myxococcus xanthus and Streptomyces coelicolor. BMC Microbiol. 2013 Dec 05; 13:279. Getsin I, Nalbandian GH, Yee DC, Vastermark A, Paparoditis PC, Reddy VS, Saier MH. PMID: 24304716.
      View in: PubMed   Mentions: 10     Fields:    Translation:Cells
    64. The transporter classification database. Nucleic Acids Res. 2014 Jan; 42(Database issue):D251-8. Saier MH, Reddy VS, Tamang DG, Västermark A. PMID: 24225317.
      View in: PubMed   Mentions: 173     Fields:    
    65. Evolutionary relationship between 5+5 and 7+7 inverted repeat folds within the amino acid-polyamine-organocation superfamily. Proteins. 2014 Feb; 82(2):336-46. Västermark Å, Saier MH. PMID: 24038584.
      View in: PubMed   Mentions: 19     Fields:    Translation:HumansAnimalsCells
    66. The transporter-opsin-G protein-coupled receptor (TOG) superfamily. FEBS J. 2013 Nov; 280(22):5780-800. Yee DC, Shlykov MA, Västermark A, Reddy VS, Arora S, Sun EI, Saier MH. PMID: 23981446.
      View in: PubMed   Mentions: 21     Fields:    Translation:HumansAnimalsCells
    67. Comparative genomics of metabolic capacities of regulons controlled by cis-regulatory RNA motifs in bacteria. BMC Genomics. 2013 Sep 02; 14:597. Sun EI, Leyn SA, Kazanov MD, Saier MH, Novichkov PS, Rodionov DA. PMID: 24060102.
      View in: PubMed   Mentions: 24     Fields:    Translation:Cells
    68. Lipid dependencies, biogenesis and cytoplasmic micellar forms of integral membrane sugar transport proteins of the bacterial phosphotransferase system. Microbiology (Reading). 2013 Nov; 159(Pt 11):2213-2224. Aboulwafa M, Saier MH. PMID: 23985145.
      View in: PubMed   Mentions:
    69. Bioinformatic analyses of integral membrane transport proteins encoded within the genome of the planctomycetes species, Rhodopirellula baltica. Biochim Biophys Acta. 2014 Jan; 1838(1 Pt B):193-215. Paparoditis P, Västermark A, Le AJ, Fuerst JA, Saier MH. PMID: 23969110.
      View in: PubMed   Mentions: 9     Fields:    Translation:Cells
    70. Microcompartments and protein machines in prokaryotes. J Mol Microbiol Biotechnol. 2013; 23(4-5):243-69. Saier MH. PMID: 23920489.
      View in: PubMed   Mentions: 7     Fields:    Translation:Cells
    71. Topological and phylogenetic analyses of bacterial holin families and superfamilies. Biochim Biophys Acta. 2013 Nov; 1828(11):2654-71. Reddy BL, Saier MH. PMID: 23856191.
      View in: PubMed   Mentions: 21     Fields:    Translation:Cells
    72. Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters. BMC Microbiol. 2013 May 06; 13:98. Zheng WH, Västermark Å, Shlykov MA, Reddy V, Sun EI, Saier MH. PMID: 23647830.
      View in: PubMed   Mentions: 13     Fields:    Translation:Cells
    73. Membranous organelles in bacteria. J Mol Microbiol Biotechnol. 2013; 23(1-2):5-12. Saier MH, Bogdanov MV. PMID: 23615191.
      View in: PubMed   Mentions: 5     Fields:    Translation:Cells
    74. Subcellular localization and logistics of integral membrane protein biogenesis in Escherichia coli. J Mol Microbiol Biotechnol. 2013; 23(1-2):24-34. Bogdanov M, Aboulwafa M, Saier MH. PMID: 23615193.
      View in: PubMed   Mentions: 2     Fields:    Translation:Cells
    75. Genetic engineering of the phosphocarrier protein NPr of the Escherichia coli phosphotransferase system selectively improves sugar uptake activity. J Biol Chem. 2012 Aug 24; 287(35):29931-9. Lopez-de Los Santos Y, Chan H, Cantu VA, Rettner R, Sanchez F, Zhang Z, Saier MH, Soberon X. PMID: 22767600.
      View in: PubMed   Mentions: 1     Fields:    Translation:Cells
    76. Transformative research: definitions, approaches and consequences. Theory Biosci. 2012 Jun; 131(2):117-23. Trevors JT, Pollack GH, Saier MH, Masson L. PMID: 22628127.
      View in: PubMed   Mentions: 3     Fields:    Translation:Humans
    77. The amino acid-polyamine-organocation superfamily. J Mol Microbiol Biotechnol. 2012; 22(2):105-13. Wong FH, Chen JS, Reddy V, Day JL, Shlykov MA, Wakabayashi ST, Saier MH. PMID: 22627175.
      View in: PubMed   Mentions: 45     Fields:    Translation:Cells
    78. The major facilitator superfamily (MFS) revisited. FEBS J. 2012 Jun; 279(11):2022-35. Reddy VS, Shlykov MA, Castillo R, Sun EI, Saier MH. PMID: 22458847.
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    79. BioV Suite--a collection of programs for the study of transport protein evolution. FEBS J. 2012 Jun; 279(11):2036-46. Reddy VS, Saier MH. PMID: 22568782.
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    80. Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on multiple alignments. J Mol Microbiol Biotechnol. 2011; 21(3-4):83-96. Chen JS, Reddy V, Chen JH, Shlykov MA, Zheng WH, Cho J, Yen MR, Saier MH. PMID: 22286036.
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    81. Did adaptive and directed mutation evolve to accelerate stress-induced evolutionary change? J Mol Microbiol Biotechnol. 2011; 21(1-2):5-7. Saier MH. PMID: 22248538.
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    82. Transposon-mediated adaptive and directed mutations and their potential evolutionary benefits. J Mol Microbiol Biotechnol. 2011; 21(1-2):59-70. Zhang Z, Saier MH. PMID: 22248543.
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    83. Bioinformatic characterization of the 4-Toluene Sulfonate Uptake Permease (TSUP) family of transmembrane proteins. Biochim Biophys Acta. 2012 Mar; 1818(3):703-17. Shlykov MA, Zheng WH, Chen JS, Saier MH. PMID: 22192777.
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    84. Comparative analyses of transport proteins encoded within the genomes of Mycobacterium tuberculosis and Mycobacterium leprae. Biochim Biophys Acta. 2012 Mar; 1818(3):776-97. Youm J, Saier MH. PMID: 22179038.
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    85. Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome Biol. 2011 Oct 17; 12(10):R100. Coyne RS, Hannick L, Shanmugam D, Hostetler JB, Brami D, Joardar VS, Johnson J, Radune D, Singh I, Badger JH, Kumar U, Saier M, Wang Y, Cai H, Gu J, Mather MW, Vaidya AB, Wilkes DE, Rajagopalan V, Asai DJ, Pearson CG, Findly RC, Dickerson HW, Wu M, Martens C, Van de Peer Y, Roos DS, Cassidy-Hanley DM, Clark TG. PMID: 22004680.
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    86. Biophysical studies of the membrane-embedded and cytoplasmic forms of the glucose-specific Enzyme II of the E. coli phosphotransferase system (PTS). PLoS One. 2011; 6(9):e24088. Aboulwafa M, Saier MH. PMID: 21935376.
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    87. Identifying relevant data for a biological database: handcrafted rules versus machine learning. IEEE/ACM Trans Comput Biol Bioinform. 2011 May-Jun; 8(3):851-7. Sehgal AK, Das S, Noto K, Saier MH, Elkan C. PMID: 21393656.
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    88. Bioinformatic characterization of the trimeric intracellular cation-specific channel protein family. J Membr Biol. 2011 May; 241(2):77-101. Silverio AL, Saier MH. PMID: 21519847.
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    89. Evolution of the oligopeptide transporter family. J Membr Biol. 2011 Mar; 240(2):89-110. Gomolplitinant KM, Saier MH. PMID: 21347612.
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    90. Pathways of transport protein evolution: recent advances. Biol Chem. 2011 Jan; 392(1-2):5-12. Lam VH, Lee JH, Silverio A, Chan H, Gomolplitinant KM, Povolotsky TL, Orlova E, Sun EI, Welliver CH, Saier MH. PMID: 21194372.
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    91. Thermodynamic perspectives on genetic instructions, the laws of biology and diseased states. C R Biol. 2011 Jan; 334(1):1-5. Trevors JT, Saier MH. PMID: 21262480.
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    92. The bacterial intimins and invasins: a large and novel family of secreted proteins. PLoS One. 2010 Dec 22; 5(12):e14403. Tsai JC, Yen MR, Castillo R, Leyton DL, Henderson IR, Saier MH. PMID: 21203509.
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    93. The p-type ATPase superfamily. J Mol Microbiol Biotechnol. 2010; 19(1-2):5-104. Chan H, Babayan V, Blyumin E, Gandhi C, Hak K, Harake D, Kumar K, Lee P, Li TT, Liu HY, Lo TC, Meyer CJ, Stanford S, Zamora KS, Saier MH. PMID: 20962537.
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    94. Functional Promiscuity of Homologues of the Bacterial ArsA ATPases. Int J Microbiol. 2010; 2010:187373. Castillo R, Saier MH. PMID: 20981284.
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    95. Defense against cannibalism: the SdpI family of bacterial immunity/signal transduction proteins. J Membr Biol. 2010 Jun; 235(3):145-62. Povolotsky TL, Orlova E, Tamang DG, Saier MH. PMID: 20563570.
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    96. The autoinducer-2 exporter superfamily. J Mol Microbiol Biotechnol. 2010; 18(4):195-205. Rettner RE, Saier MH. PMID: 20559013.
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    97. Animal Ca2+ release-activated Ca2+ (CRAC) channels appear to be homologous to and derived from the ubiquitous cation diffusion facilitators. BMC Res Notes. 2010 Jun 03; 3:158. Matias MG, Gomolplitinant KM, Tamang DG, Saier MH. PMID: 20525303.
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    98. Transcriptional Regulation of the rsbV Promoter Controlling Stress Responses to Ethanol, Carbon Limitation, and Phosphorous Limitation in Bacillus subtilis. Int J Microbiol. 2010; 2010:263410. Choi SK, Saier MH. PMID: 20454630.
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    99. In vitro phosphorylation of key metabolic enzymes from Bacillus subtilis: PrkC phosphorylates enzymes from different branches of basic metabolism. J Mol Microbiol Biotechnol. 2010; 18(3):129-40. Pietack N, Becher D, Schmidl SR, Saier MH, Hecker M, Commichau FM, Stülke J. PMID: 20389117.
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    100. Bacterial Adaptor Membrane Fusion Proteins and the Structurally Dissimilar Outer Membrane Auxiliary Proteins Have Exchanged Central Domains in alpha-Proteobacteria. Int J Microbiol. 2010; 2010:589391. Xiao AY, Wang J, Saier MH. PMID: 20379386.
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    101. Precise excision of IS5 from the intergenic region between the fucPIK and the fucAO operons and mutational control of fucPIK operon expression in Escherichia coli. J Bacteriol. 2010 Apr; 192(7):2013-9. Zhang Z, Yen MR, Saier MH. PMID: 20097855.
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    102. Multidrug resistance: phylogenetic characterization of superfamilies of secondary carriers that include drug exporters. Methods Mol Biol. 2010; 637:47-64. Yen MR, Chen JS, Marquez JL, Sun EI, Saier MH. PMID: 20419429.
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    103. Education for Humanity. Water Air Soil Pollut. 2010 Feb; 206(1-4):1-2. Trevors JT, Saier MH. PMID: 22247577.
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    104. Global Pollution: How Much Is Too Much? Water Air Soil Pollut. 2009 Nov; 204(1-4):1-3. Trevors JT, Saier MH. PMID: 19898672.
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    105. A novel mechanism of transposon-mediated gene activation. PLoS Genet. 2009 Oct; 5(10):e1000689. Zhang Z, Saier MH. PMID: 19834539.
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    106. Membrane porters of ATP-binding cassette transport systems are polyphyletic. J Membr Biol. 2009 Sep; 231(1):1-10. Wang B, Dukarevich M, Sun EI, Yen MR, Saier MH. PMID: 19806386.
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    107. Bioinformatic analyses of transmembrane transport: novel software for deducing protein phylogeny, topology, and evolution. J Mol Microbiol Biotechnol. 2009; 17(4):163-76. Yen MR, Choi J, Saier MH. PMID: 19776645.
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    108. A mechanism of transposon-mediated directed mutation. Mol Microbiol. 2009 Oct; 74(1):29-43. Zhang Z, Saier MH. PMID: 19682247.
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    109. Bioinformatic characterization of p-type ATPases encoded within the fully sequenced genomes of 26 eukaryotes. J Membr Biol. 2009 Jun; 229(3):115-30. Thever MD, Saier MH. PMID: 19548020.
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    110. Comprehensive analyses of transport proteins encoded within the genome of "Aromatoleum aromaticum" strain EbN1. J Membr Biol. 2009 May; 229(2):53-90. Tamang DG, Rabus R, Barabote RD, Saier MH. PMID: 19506936.
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    111. The Transporter Classification Database: recent advances. Nucleic Acids Res. 2009 Jan; 37(Database issue):D274-8. Saier MH, Yen MR, Noto K, Tamang DG, Elkan C. PMID: 19022853.
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    112. A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome Biol. 2008; 9(11):R158. Podar M, Anderson I, Makarova KS, Elkins JG, Ivanova N, Wall MA, Lykidis A, Mavromatis K, Sun H, Hudson ME, Chen W, Deciu C, Hutchison D, Eads JR, Anderson A, Fernandes F, Szeto E, Lapidus A, Kyrpides NC, Saier MH, Richardson PM, Rachel R, Huber H, Eisen JA, Koonin EV, Keller M, Stetter KO. PMID: 19000309.
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    113. A stochastic automaton shows how enzyme assemblies may contribute to metabolic efficiency. BMC Syst Biol. 2008 Mar 25; 2:27. Amar P, Legent G, Thellier M, Ripoll C, Bernot G, Nystrom T, Saier MH, Norris V. PMID: 18366733.
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    114. The bacterial chromosome. Crit Rev Biochem Mol Biol. 2008 Mar-Apr; 43(2):89-134. Saier MH. PMID: 18365861.
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    115. Characterization of the E. coli glucose permease fused to the maltose-binding protein. J Basic Microbiol. 2008 Feb; 48(1):3-9. Aboulwafa M, Saier MH. PMID: 18247392.
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    116. Protein secretion and membrane insertion systems in bacteria and eukaryotic organelles. Adv Appl Microbiol. 2008; 65:141-97. Saier MH, Ma CH, Rodgers L, Tamang DG, Yen MR. PMID: 19026865.
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    117. The phagosomal nutrient transporter (Pht) family. Microbiology (Reading). 2008 Jan; 154(Pt 1):42-53. Chen DE, Podell S, Sauer JD, Swanson MS, Saier MH. PMID: 18174124.
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    118. Comprehensive analysis of transport proteins encoded within the genome of Bdellovibrio bacteriovorus. Genomics. 2007 Oct; 90(4):424-46. Barabote RD, Rendulic S, Schuster SC, Saier MH. PMID: 17706914.
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    119. Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli. BMC Microbiol. 2007 Jun 08; 7:53. Gutierrez-Ríos RM, Freyre-Gonzalez JA, Resendis O, Collado-Vides J, Saier M, Gosset G. PMID: 17559662.
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    120. Protein secretion and membrane insertion systems in gram-negative bacteria. J Membr Biol. 2006; 214(2):75-90. Saier MH. PMID: 17546510.
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    121. Evolutionary origins of members of a superfamily of integral membrane cytochrome c biogenesis proteins. Biochim Biophys Acta. 2007 Sep; 1768(9):2164-81. Lee JH, Harvat EM, Stevens JM, Ferguson SJ, Saier MH. PMID: 17706591.
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    122. Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis. Biochemistry. 2007 May 01; 46(17):5218-25. Zhang Z, Ma C, Pornillos O, Xiu X, Chang G, Saier MH. PMID: 17417881.
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    123. Combinatorial transcriptional control of the lactose operon of Escherichia coli. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):6043-8. Kuhlman T, Zhang Z, Saier MH, Hwa T. PMID: 17376875.
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    124. Gap junctional proteins of animals: the innexin/pannexin superfamily. Prog Biophys Mol Biol. 2007 May-Jun; 94(1-2):5-14. Yen MR, Saier MH. PMID: 17507077.
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    125. Functional taxonomy of bacterial hyperstructures. Microbiol Mol Biol Rev. 2007 Mar; 71(1):230-53. Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K. PMID: 17347523.
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    126. Transport capabilities of eleven gram-positive bacteria: comparative genomic analyses. Biochim Biophys Acta. 2007 Jun; 1768(6):1342-66. Lorca GL, Barabote RD, Zlotopolski V, Tran C, Winnen B, Hvorup RN, Stonestrom AJ, Nguyen E, Huang LW, Kim DS, Saier MH. PMID: 17490609.
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    127. The bile/arsenite/riboflavin transporter (BART) superfamily. FEBS J. 2007 Feb; 274(3):612-29. Mansour NM, Sawhney M, Tamang DG, Vogl C, Saier MH. PMID: 17288550.
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    128. In vitro interconversion of the soluble and membrane- integrated forms of the Escherichia coli glucose enzyme II of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system. J Mol Microbiol Biotechnol. 2007; 12(3-4):263-8. Aboulwafa M, Saier MH. PMID: 17587874.
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    129. Active transport in communication, protection and nutrition. J Mol Microbiol Biotechnol. 2007; 12(3-4):161-4. Saier MH. PMID: 17587865.
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    130. Toward a hyperstructure taxonomy. Annu Rev Microbiol. 2007; 61:309-29. Norris V, den Blaauwen T, Doi RH, Harshey RM, Janniere L, Jiménez-Sánchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Misevic G, Ripoll C, Saier M, Skarstad K, Thellier M. PMID: 17896876.
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    131. Are Megacities Sustainable? Water Air Soil Pollut. 2007; 178(1):1-3. Saier MH. PMID: 32214525.
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    132. Protein-translocating trimeric autotransporters of gram-negative bacteria. J Bacteriol. 2006 Aug; 188(16):5655-67. Kim DS, Chao Y, Saier MH. PMID: 16885434.
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    133. Are Megacities Sustainable? Water Air Soil Pollut. 2008; 191(1):1-3. Saier MH. PMID: 32214526.
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    134. Extra domains in secondary transport carriers and channel proteins. Biochim Biophys Acta. 2006 Oct; 1758(10):1557-79. Barabote RD, Tamang DG, Abeywardena SN, Fallah NS, Fu JY, Lio JK, Mirhosseini P, Pezeshk R, Podell S, Salampessy ML, Thever MD, Saier MH. PMID: 16905115.
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    135. Evolutionary appearance of H+-translocating pyrophosphatases. Microbiology (Reading). 2006 May; 152(Pt 5):1243-1247. Au KM, Barabote RD, Hu KY, Saier MH. PMID: 16622041.
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    136. The iron/lead transporter superfamily of Fe/Pb2+ uptake systems. J Mol Microbiol Biotechnol. 2006; 11(1-2):1-9. Debut AJ, Dumay QC, Barabote RD, Saier MH. PMID: 16825785.
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    137. The bioinformatic study of transmembrane molecular transport. J Mol Microbiol Biotechnol. 2006; 11(6):289-90. Saier MH, Ren Q. PMID: 17114892.
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    138. Engineering transport protein function: theoretical and technical considerations using the sugar-transporting phosphotransferase system of Escherichia coli as a model system. J Mol Microbiol Biotechnol. 2006; 11(6):302-7. Soberón X, Saier MH. PMID: 17114894.
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    139. Topological predictions for integral membrane permeases of the phosphoenolpyruvate:sugar phosphotransferase system. J Mol Microbiol Biotechnol. 2006; 11(6):345-60. Nguyen TX, Yen MR, Barabote RD, Saier MH. PMID: 17114898.
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    140. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Nucleic Acids Res. 2006 Jan 01; 34(Database issue):D181-6. Saier MH, Tran CV, Barabote RD. PMID: 16381841.
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    141. The copper transporter (Ctr) family of Cu+ uptake systems. J Mol Microbiol Biotechnol. 2006; 11(1-2):10-9. Dumay QC, Debut AJ, Mansour NM, Saier MH. PMID: 16825786.
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    142. The cecropin superfamily of toxic peptides. J Mol Microbiol Biotechnol. 2006; 11(1-2):94-103. Tamang DG, Saier MH. PMID: 16825792.
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    143. Mechanism of CcpA-mediated glucose repression of the resABCDE operon of Bacillus subtilis. J Mol Microbiol Biotechnol. 2006; 11(1-2):104-10. Choi SK, Saier MH. PMID: 16825793.
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    144. Comparative genomic analyses of the bacterial phosphotransferase system. Microbiol Mol Biol Rev. 2005 Dec; 69(4):608-34. Barabote RD, Saier MH. PMID: 16339738.
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    145. Catabolite repression and activation in Bacillus subtilis: dependency on CcpA, HPr, and HprK. J Bacteriol. 2005 Nov; 187(22):7826-39. Lorca GL, Chung YJ, Barabote RD, Weyler W, Schilling CH, Saier MH. PMID: 16267306.
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    146. Regulation of sigL expression by the catabolite control protein CcpA involves a roadblock mechanism in Bacillus subtilis: potential connection between carbon and nitrogen metabolism. J Bacteriol. 2005 Oct; 187(19):6856-61. Choi SK, Saier MH. PMID: 16166551.
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    147. The bestrophin family of anion channels: identification of prokaryotic homologues. Mol Membr Biol. 2005 Jul-Aug; 22(4):291-302. Hagen AR, Barabote RD, Saier MH. PMID: 16154901.
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    148. Functional interactions between the carbon and iron utilization regulators, Crp and Fur, in Escherichia coli. J Bacteriol. 2005 Feb; 187(3):980-90. Zhang Z, Gosset G, Barabote R, Gonzalez CS, Cuevas WA, Saier MH. PMID: 15659676.
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    149. Evolution of the bacterial phosphotransferase system: from carriers and enzymes to group translocators. Biochem Soc Trans. 2005 Feb; 33(Pt 1):220-4. Saier MH, Hvorup RN, Barabote RD. PMID: 15667312.
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    150. Bioinformatic analyses of bacterial HPr kinase/phosphorylase homologues. Res Microbiol. 2005 Apr; 156(3):443-51. Stonestrom A, Barabote RD, Gonzalez CF, Saier MH. PMID: 15808949.
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    151. Lysophospholipid flipping across the Escherichia coli inner membrane catalyzed by a transporter (LplT) belonging to the major facilitator superfamily. J Biol Chem. 2005 Mar 25; 280(12):12028-34. Harvat EM, Zhang YM, Tran CV, Zhang Z, Frank MW, Rock CO, Saier MH. PMID: 15661733.
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    152. Biochemical characterization of phosphoryl transfer involving HPr of the phosphoenolpyruvate-dependent phosphotransferase system in Treponema denticola, an organism that lacks PTS permeases. Biochemistry. 2005 Jan 18; 44(2):598-608. Gonzalez CF, Stonestrom AJ, Lorca GL, Saier MH. PMID: 15641785.
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    153. Ser/Thr/Tyr protein phosphorylation in bacteria - for long time neglected, now well established. J Mol Microbiol Biotechnol. 2005; 9(3-4):125-31. Deutscher J, Saier MH. PMID: 16415586.
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    154. Probiotics and prebiotics in human health. J Mol Microbiol Biotechnol. 2005; 10(1):22-5. Saier MH, Mansour NM. PMID: 16491023.
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    155. Regulation of pho regulon gene expression by the carbon control protein A, CcpA, in Bacillus subtilis. J Mol Microbiol Biotechnol. 2005; 10(1):40-50. Choi SK, Saier MH. PMID: 16491025.
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    156. Hypothesis: chemotaxis in Escherichia coli results from hyper-structure dynamics. J Mol Microbiol Biotechnol. 2005; 10(1):1-14. Cabin-Flaman A, Ripoll C, Saier MH, Norris V. PMID: 16491021.
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    157. Genomic analyses of transport proteins in Ralstonia metallidurans. Comp Funct Genomics. 2005; 6(1-2):17-56. von Rozycki T, Nies DH, Saier MH. PMID: 18629293.
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    158. Characterization of soluble enzyme II complexes of the Escherichia coli phosphotransferase system. J Bacteriol. 2004 Dec; 186(24):8453-62. Aboulwafa M, Saier MH. PMID: 15576795.
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    159. Topological analysis of integral membrane constituents of prokaryotic ABC efflux systems. Res Microbiol. 2005 Mar; 156(2):270-7. Khwaja M, Ma Q, Saier MH. PMID: 15748994.
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    160. Sequence similarity between multidrug resistance efflux pumps of the ABC and RND superfamilies. Microbiology (Reading). 2004 Aug; 150(Pt 8):2493-2495. Kim SH, Chang AB, Saier MH. PMID: 15289545.
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    161. The IUBMB-endorsed transporter classification system. Mol Biotechnol. 2004 Jul; 27(3):253-62. Busch W, Saier MH, International Union of Biochemistry and Molecular Biology (IUBMB) . PMID: 15247498.
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    162. Transcriptome analysis of Crp-dependent catabolite control of gene expression in Escherichia coli. J Bacteriol. 2004 Jun; 186(11):3516-24. Gosset G, Zhang Z, Nayyar S, Cuevas WA, Saier MH. PMID: 15150239.
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    163. Phylogeny as a guide to structure and function of membrane transport proteins. Mol Membr Biol. 2004 May-Jun; 21(3):171-81. Chang AB, Lin R, Keith Studley W, Tran CV, Saier MH. PMID: 15204625.
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    164. In silico and transcriptional analysis of carbohydrate uptake systems of Streptomyces coelicolor A3(2). J Bacteriol. 2004 Mar; 186(5):1362-73. Bertram R, Schlicht M, Mahr K, Nothaft H, Saier MH, Titgemeyer F. PMID: 14973030.
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    165. Evolution of bacterial type III protein secretion systems. Trends Microbiol. 2004 Mar; 12(3):113-5. Saier MH. PMID: 15001186.
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    166. Sequence analyses of cyanobacterial bicarbonate transporters and their homologues. J Mol Microbiol Biotechnol. 2004; 7(3):102-8. von Rozycki T, Schultzel MA, Saier MH. PMID: 15263814.
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    167. The principal chloroquine resistance protein of Plasmodium falciparum is a member of the drug/metabolite transporter superfamily. Microbiology (Reading). 2004 Jan; 150(Pt 1):1-3. Tran CV, Saier MH. PMID: 14702390.
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    168. Carbonic anhydrases fused to anion transporters of the SulP family: evidence for a novel type of bicarbonate transporter. J Mol Microbiol Biotechnol. 2004; 8(3):169-76. Felce J, Saier MH. PMID: 16088218.
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    169. The YedZ family: possible heme binding proteins that can be fused to transporters and electron carriers. J Mol Microbiol Biotechnol. 2004; 8(3):129-40. von Rozycki T, Yen MR, Lende EE, Saier MH. PMID: 16088215.
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    170. Biofilm-defective mutants of Bacillus subtilis. J Mol Microbiol Biotechnol. 2004; 8(3):177-88. Chagneau C, Saier MH. PMID: 16088219.
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    171. The ion transporter superfamily. Biochim Biophys Acta. 2003 Dec 03; 1618(1):79-92. Prakash S, Cooper G, Singhi S, Saier MH. PMID: 14643936.
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    172. Dependency of sugar transport and phosphorylation by the phosphoenolpyruvate-dependent phosphotransferase system on membranous phosphatidylethanolamine in Escherichia coli: studies with a pssA mutant lacking phosphatidylserine synthase. Arch Microbiol. 2004 Jan; 181(1):26-34. Aboulwafa M, Hvorup R, Saier MH. PMID: 14634719.
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    173. Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella. Microbiology (Reading). 2003 Nov; 149(Pt 11):3051-3072. Peabody CR, Chung YJ, Yen MR, Vidal-Ingigliardi D, Pugsley AP, Saier MH. PMID: 14600218.
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    174. The tripartite tricarboxylate transporter (TTT) family. Res Microbiol. 2003 Sep; 154(7):457-65. Winnen B, Hvorup RN, Saier MH. PMID: 14499931.
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    175. Molecular modeling of the bacterial outer membrane receptor energizer, ExbBD/TonB, based on homology with the flagellar motor, MotAB. Biochim Biophys Acta. 2003 Aug 07; 1614(2):201-10. Zhai YF, Heijne W, Saier MH. PMID: 12896813.
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    176. A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily. Arch Microbiol. 2003 Aug; 180(2):88-100. Zhang Z, Feige JN, Chang AB, Anderson IJ, Brodianski VM, Vitreschak AG, Gelfand MS, Saier MH. PMID: 12819857.
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    177. Tracing pathways of transport protein evolution. Mol Microbiol. 2003 Jun; 48(5):1145-56. Saier MH. PMID: 12787345.
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    178. Identification of the L-aspartate transporter in Bacillus subtilis. J Bacteriol. 2003 May; 185(10):3218-22. Lorca G, Winnen B, Saier MH. PMID: 12730183.
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    179. The ascorbate transporter of Escherichia coli. J Bacteriol. 2003 Apr; 185(7):2243-50. Zhang Z, Aboulwafa M, Smith MH, Saier MH. PMID: 12644495.
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    180. Soluble sugar permeases of the phosphotransferase system in Escherichia coli: evidence for two physically distinct forms of the proteins in vivo. Mol Microbiol. 2003 Apr; 48(1):131-41. Aboulwafa M, Saier M. PMID: 12657050.
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    181. Protein secretion systems of Pseudomonas aeruginosa and P fluorescens. Biochim Biophys Acta. 2003 Apr 01; 1611(1-2):223-33. Ma Q, Zhai Y, Schneider JC, Ramseier TM, Saier MH. PMID: 12659964.
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    182. The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily. Eur J Biochem. 2003 Mar; 270(5):799-813. Hvorup RN, Winnen B, Chang AB, Jiang Y, Zhou XF, Saier MH. PMID: 12603313.
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    183. Two families of mechanosensitive channel proteins. Microbiol Mol Biol Rev. 2003 Mar; 67(1):66-85, table of contents. Pivetti CD, Yen MR, Miller S, Busch W, Tseng YH, Booth IR, Saier MH. PMID: 12626684.
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    184. Studies on the Escherichia coli glucose-specific permease, PtsG, with a point mutation in its N-terminal amphipathic leader sequence. Microbiology (Reading). 2003 Mar; 149(Pt 3):763-771. Aboulwafa M, Chung YJ, Wai HH, Saier MH. PMID: 12634344.
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    185. The general protein secretory pathway: phylogenetic analyses leading to evolutionary conclusions. Biochim Biophys Acta. 2003 Jan 10; 1609(1):115-25. Cao TB, Saier MH. PMID: 12507766.
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    186. Web-based programs for the display and analysis of transmembrane alpha-helices in aligned protein sequences. J Mol Microbiol Biotechnol. 2003; 5(1):1-6. Zhou X, Yang NM, Tran CV, Hvorup RN, Saier MH. PMID: 12673055.
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    187. An automated program to screen databases for members of protein families. J Mol Microbiol Biotechnol. 2003; 5(1):7-10. Zhou X, Hvorup RN, Saier MH. PMID: 12673056.
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    188. The urea transporter (UT) family: bioinformatic analyses leading to structural, functional, and evolutionary predictions. Recept Channels. 2003; 9(6):345-52. Minocha R, Studley K, Saier MH. PMID: 14698962.
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    189. Reversing transmembrane electron flow: the DsbD and DsbB protein families. J Mol Microbiol Biotechnol. 2003; 5(3):133-49. Kimball RA, Martin L, Saier MH. PMID: 12766342.
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    190. The IUBMB-endorsed transporter classification system. Methods Mol Biol. 2003; 227:21-36. Busch W, Saier MH. PMID: 12824641.
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    191. Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family. J Mol Microbiol Biotechnol. 2003; 6(3-4):191-205. Hvorup R, Chang AB, Saier MH. PMID: 15153772.
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    192. Dependency of sugar transport and phosphorylation by the phosphoenolpyruvate-dependent phosphotransferase system on membranous phosphatidyl glycerol in Escherichia coli: studies with a pgsA mutant lacking phosphatidyl glycerophosphate synthase. Res Microbiol. 2002 Dec; 153(10):667-77. Aboulwafa M, Saier MH. PMID: 12558186.
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    193. Sequence similarity between the channel-forming domains of voltage-gated ion channel proteins and the C-terminal domains of secondary carriers of the major facilitator superfamily. Microbiology (Reading). 2002 Dec; 148(Pt 12):3760-2. Hvorup RN, Saier MH. PMID: 12480878.
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    194. Domain analysis of transcriptional regulators bearing PTS regulatory domains. Res Microbiol. 2002 Oct; 153(8):519-26. Greenberg DB, Stülke J, Saier MH. PMID: 12437213.
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    195. The beta-barrel finder (BBF) program, allowing identification of outer membrane beta-barrel proteins encoded within prokaryotic genomes. Protein Sci. 2002 Sep; 11(9):2196-207. Zhai Y, Saier MH. PMID: 12192075.
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    196. Phylogeny of phosphoryl transfer proteins of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system. Res Microbiol. 2002 Sep; 153(7):405-15. Hu KY, Saier MH. PMID: 12405346.
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    197. Discovering lactic acid bacteria by genomics. Antonie Van Leeuwenhoek. 2002 Aug; 82(1-4):29-58. Klaenhammer T, Altermann E, Arigoni F, Bolotin A, Breidt F, Broadbent J, Cano R, Chaillou S, Deutscher J, Gasson M, van de Guchte M, Guzzo J, Hartke A, Hawkins T, Hols P, Hutkins R, Kleerebezem M, Kok J, Kuipers O, Lubbers M, Maguin E, McKay L, Mills D, Nauta A, Overbeek R, Pel H, Pridmore D, Saier M, van Sinderen D, Sorokin A, Steele J, O'Sullivan D, de Vos W, Weimer B, Zagorec M, Siezen R. PMID: 12369195.
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    198. A simple sensitive program for detecting internal repeats in sets of multiply aligned homologous proteins. J Mol Microbiol Biotechnol. 2002 Jul; 4(4):375-7. Zhai Y, Saier MH. PMID: 12125818.
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    199. Protein-translocating outer membrane porins of Gram-negative bacteria. Biochim Biophys Acta. 2002 May 03; 1562(1-2):6-31. Yen MR, Peabody CR, Partovi SM, Zhai Y, Tseng YH, Saier MH. PMID: 11988218.
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    200. Overexpression of the Escherichia coli sugE gene confers resistance to a narrow range of quaternary ammonium compounds. J Bacteriol. 2002 May; 184(9):2543-5. Chung YJ, Saier MH. PMID: 11948170.
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    201. Sec61beta--a component of the archaeal protein secretory system. Trends Biochem Sci. 2002 Apr; 27(4):170-1. Kinch LN, Saier MH, Grishin NV. PMID: 11943537.
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    202. Voltage-gated H+ channels associated with human phagocyte superoxide-generating NADPH oxidases: sequence comparisons, structural predictions, and phylogenetic analyses. Mol Membr Biol. 2002 Apr-Jun; 19(2):137-47. Kimball RA, Saier MH. PMID: 12126231.
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    203. Sequence and phylogenetic analyses of the twin-arginine targeting (Tat) protein export system. Arch Microbiol. 2002 Jun; 177(6):441-50. Yen MR, Tseng YH, Nguyen EH, Wu LF, Saier MH. PMID: 12029389.
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    204. The EcoCyc Database. Nucleic Acids Res. 2002 Jan 01; 30(1):56-8. Karp PD, Riley M, Saier M, Paulsen IT, Collado-Vides J, Paley SM, Pellegrini-Toole A, Bonavides C, Gama-Castro S. PMID: 11752253.
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    205. A web-based Tree View (TV) program for the visualization of phylogenetic trees. J Mol Microbiol Biotechnol. 2002 Jan; 4(1):69-70. Zhai Y, Tchieu J, Saier MH. PMID: 11763971.
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    206. The ubiquitous ThrE family of putative transmembrane amino acid efflux transporters. Res Microbiol. 2002 Jan-Feb; 153(1):19-25. Yen MR, Tseng YH, Simic P, Sahm H, Eggeling L, Saier MH. PMID: 11881894.
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    207. Hyperstructures, genome analysis and I-cells. Acta Biotheor. 2002; 50(4):357-73. Amar P, Ballet P, Barlovatz-Meimon G, Benecke A, Bernot G, Bouligand Y, Bourguine P, Delaplace F, Delosme JM, Demarty M, Fishov I, Fourmentin-Guilbert J, Fralick J, Giavitto JL, Gleyse B, Godin C, Incitti R, Képès F, Lange C, Le Sceller L, Loutellier C, Michel O, Molina F, Monnier C, Natowicz R, Norris V, Orange N, Pollard H, Raine D, Ripoll C, Rouviere-Yaniv J, Saier M, Soler P, Tambourin P, Thellier M, Tracqui P, Ussery D, Vincent JC, Vannier JP, Wiggins P, Zemirline A. PMID: 12675536.
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    208. The transporter classification (TC) system, 2002. Crit Rev Biochem Mol Biol. 2002; 37(5):287-337. Busch W, Saier MH. PMID: 12449427.
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    209. Transport capabilities encoded within the Bacillus subtilis genome. J Mol Microbiol Biotechnol. 2002 Jan; 4(1):37-67. Saier MH, Goldman SR, Maile RR, Moreno MS, Weyler W, Yang N, Paulsen IT. PMID: 11763970.
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    210. Regulation of carbon utilization by sulfur availability in Escherichia coli and Salmonella typhimurium. Microbiology (Reading). 2002 Jan; 148(Pt 1):123-131. Quan JA, Schneider BL, Paulsen IT, Yamada M, Kredich NM, Saier MH. PMID: 11782505.
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    211. The bacterial phosphotransferase system: structure, function, regulation and evolution. J Mol Microbiol Biotechnol. 2001 Jul; 3(3):325-7. Saier MH. PMID: 11361062.
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    212. Phylogeny of multidrug transporters. Semin Cell Dev Biol. 2001 Jun; 12(3):205-13. Saier MH, Paulsen IT. PMID: 11428913.
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    213. Whole genome analyses of transporters in spirochetes: Borrelia burgdorferi and Treponema pallidum. J Mol Microbiol Biotechnol. 2000 Oct; 2(4):393-9. Saier MH, Paulsen IT. PMID: 11075911.
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    214. Vectorial metabolism and the evolution of transport systems. J Bacteriol. 2000 Sep; 182(18):5029-35. Saier MH. PMID: 10960084.
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    215. Families of transmembrane transporters selective for amino acids and their derivatives. Microbiology (Reading). 2000 Aug; 146 ( Pt 8):1775-1795. Saier MH. PMID: 10931885.
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    216. The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Microbiology (Reading). 2000 Aug; 146 ( Pt 8):1797-1814. Jack DL, Paulsen IT, Saier MH. PMID: 10931886.
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    217. A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev. 2000 Jun; 64(2):354-411. Saier MH. PMID: 10839820.
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    218. Families of transmembrane sugar transport proteins. Mol Microbiol. 2000 Feb; 35(4):699-710. Saier MH. PMID: 10692148.
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    219. TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters. Microbiology (Reading). 1999 Dec; 145 ( Pt 12):3431-3445. Rabus R, Jack DL, Kelly DJ, Saier MH. PMID: 10627041.
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    220. Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis. Microbiology (Reading). 1999 Dec; 145 ( Pt 12):3419-3429. Reizer J, Bachem S, Reizer A, Arnaud M, Saier MH, Stülke J. PMID: 10627040.
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    221. Paralogous genes encoding transport proteins in microbial genomes. Res Microbiol. 1999 Nov-Dec; 150(9-10):689-99. Saier MH, Paulsen IT. PMID: 10673007.
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    222. Genome archeology leading to the characterization and classification of transport proteins. Curr Opin Microbiol. 1999 Oct; 2(5):555-61. Saier MH. PMID: 10508720.
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    223. Phylogenetic characterization of novel transport protein families revealed by genome analyses. Biochim Biophys Acta. 1999 Feb 25; 1422(1):1-56. Saier MH, Eng BH, Fard S, Garg J, Haggerty DA, Hutchinson WJ, Jack DL, Lai EC, Liu HJ, Nusinew DP, Omar AM, Pao SS, Paulsen IT, Quan JA, Sliwinski M, Tseng TT, Wachi S, Young GB. PMID: 10082980.
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    224. Eukaryotic transmembrane solute transport systems. Int Rev Cytol. 1999; 190:61-136. Saier MH. PMID: 10331239.
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    225. Genome sequencing and informatics: new tools for biochemical discoveries. Plant Physiol. 1998 Aug; 117(4):1129-33. Saier MH. PMID: 9701568.
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    226. The glucitol permease of Escherichia coli: a tripartite permease of the phosphotransferase system. Microbiology (Reading). 1998 Jun; 144(6):1463-1464. Reizer J, Reizer A, Yamada M, Saier MH. PMID: 33789396.
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    227. Multiple mechanisms controlling carbon metabolism in bacteria. Biotechnol Bioeng. 1998 Apr 20-May 5; 58(2-3):170-4. Saier MH. PMID: 10191387.
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    228. Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria. FASEB J. 1998 Mar; 12(3):265-74. Saier MH, Paulsen IT, Sliwinski MK, Pao SS, Skurray RA, Nikaido H. PMID: 9506471.
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    229. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv Microb Physiol. 1998; 40:81-136. Saier MH. PMID: 9889977.
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    230. Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Microbiology (Reading). 1997 Aug; 143 ( Pt 8):2685-2699. Paulsen IT, Beness AM, Saier MH. PMID: 9274022.
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    231. Cra-mediated regulation of Escherichia coli adenylate cyclase. Microbiology (Reading). 1997 Mar; 143 ( Pt 3):785-792. Crasnier-Mednansky M, Park MC, Studley WK, Saier MH. PMID: 9084162.
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    232. Inducer expulsion and the occurrence of an HPr(Ser-P)-activated sugar-phosphate phosphatase in Enterococcus faecalis and Streptococcus pyogenes. Microbiology (Reading). 1996 Mar; 142 ( Pt 3):585-592. Ye JJ, Minarcik J, Saier MH. PMID: 8868433.
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    233. Catabolite repression and inducer control in Gram-positive bacteria. Microbiology (Reading). 1996 Feb; 142 ( Pt 2):217-230. Saier MH, Chauvaux S, Cook GM, Deutscher J, Paulsen IT, Reizer J, Ye JJ. PMID: 8932696.
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    234. Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli. Microbiology (Reading). 1996 Feb; 142 ( Pt 2):231-250. Reizer J, Ramseier TM, Reizer A, Charbit A, Saier MH. PMID: 8932697.
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    235. Phylogenetic analyses of the homologous transmembrane channel-forming proteins of the F0F1-ATPases of bacteria, chloroplasts and mitochondria. Microbiology (Reading). 1996 Jan; 142 ( Pt 1):17-32. Blair A, Ngo L, Park J, Paulsen IT, Saier MH. PMID: 8581162.
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    236. cAMP-cAMP receptor protein complex: five binding sites in the control region of the Escherichia coli mannitol operon. Microbiology (Reading). 1995 Aug; 141 ( Pt 8):1901-1907. Ramseier TM, Saier MH. PMID: 7551052.
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