Loading...

Milton Saier

TitleProfessor
InstitutionUniversity of California San Diego
DepartmentMolecular Biology
Address9500 Gilman Drive #0116
La Jolla CA 92093
Phone858-534-4084
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Integrative functional mapping of the Escherichia coli membrane interactome
    NIH/NIGMS R01GM109895Sep 5, 2014 - Jul 31, 2018
    Role: Principal Investigator
    TransportPDB: Center for the X-ray Structure Determination of Human Transporters
    NIH/NIGMS U54GM094610Sep 30, 2010 - Jun 30, 2015
    Role: Co-Investigator
    The Transporter Classification Database (TCDB)
    NIH/NIGMS R01GM077402Apr 1, 2006 - Feb 28, 2019
    Role: Principal Investigator
    IVEM and Image Analysis Resource
    NIH/NCRR P41RR004050Dec 12, 1988 - Mar 31, 2014
    Role: Co-Investigator
    ATP-Dependent Protein Kinases in Gram-Positive Bacteria
    NIH/NIGMS R01GM055434Dec 1, 1984 - Jun 30, 2006
    Role: Principal Investigator
    ATP-DEPENDENT PROTEIN KINASES IN GRAM-POSITIVE BACTERIA
    NIH/NIAID R01AI021702Dec 1, 1984 - Nov 30, 1996
    Role: Principal Investigator
    FUNCTION AND CONTROL OF A KIDNEY EPITHELIAL CELL LINE
    NIH/NIADDK R01AM021994Jul 1, 1979 - Mar 31, 1986
    Role: Principal Investigator
    Mechanism of Carbohydrate Transport in Bacteria
    NIH/NIGMS R01GM064368Sep 1, 1977 - Mar 31, 2006
    Role: Principal Investigator
    MECHANISM OF CARBOHYDRATE TRANSPORT IN BACTERIA
    NIH/NIAID R01AI014176Sep 1, 1977 - Mar 31, 2001
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Rodionova IA, Goodacre N, Do J, Hosseinnia A, Babu M, Uetz P, Saier MH. The uridylyltransferase, GlnD, and tRNA modification GTPase, MnmE allosterically control Escherichia coli folylpoly-?-glutamate synthase, FolC. J Biol Chem. 2018 Aug 08. PMID: 30089654.
      View in: PubMed
    2. Medrano-Soto A, Moreno-Hagelsieb G, McLaughlin D, Ye ZS, Hendargo KJ, Saier MH. Bioinformatic characterization of the Anoctamin Superfamily of Ca2+-activated ion channels and lipid scramblases. PLoS One. 2018; 13(3):e0192851. PMID: 29579047.
      View in: PubMed
    3. Rodionova IA, Goodacre N, Babu M, Emili A, Uetz P, Saier MH. The Nitrogen Regulatory PII Protein (GlnB) and N-Acetylglucosamine 6-Phosphate Epimerase (NanE) Allosterically Activate Glucosamine 6-Phosphate Deaminase (NagB) in Escherichia coli. J Bacteriol. 2018 Mar 01; 200(5). PMID: 29229699.
      View in: PubMed
    4. Heidari Tajabadi F, Medrano-Soto A, Ahmadzadeh M, Salehi Jouzani G, Saier MH. Comparative Analyses of Transport Proteins Encoded within the Genomes of Bdellovibrio bacteriovorus HD100 and Bdellovibrio exovorus JSS. J Mol Microbiol Biotechnol. 2017; 27(6):332-349. PMID: 29212086.
      View in: PubMed
    5. Babu M, Bundalovic-Torma C, Calmettes C, Phanse S, Zhang Q, Jiang Y, Minic Z, Kim S, Mehla J, Gagarinova A, Rodionova I, Kumar A, Guo H, Kagan O, Pogoutse O, Aoki H, Deineko V, Caufield JH, Holtzapple E, Zhang Z, Vastermark A, Pandya Y, Lai CC, El Bakkouri M, Hooda Y, Shah M, Burnside D, Hooshyar M, Vlasblom J, Rajagopala SV, Golshani A, Wuchty S, F Greenblatt J, Saier M, Uetz P, F Moraes T, Parkinson J, Emili A. Global landscape of cell envelope protein complexes in Escherichia coli. Nat Biotechnol. 2018 Jan; 36(1):103-112. PMID: 29176613.
      View in: PubMed
    6. Moreno-Hagelsieb G, Vitug B, Medrano-Soto A, Saier MH. The Membrane Attack Complex/Perforin Superfamily. J Mol Microbiol Biotechnol. 2017; 27(4):252-267. PMID: 29145176.
      View in: PubMed
    7. Humayun MZ, Zhang Z, Butcher AM, Moshayedi A, Saier MH. Hopping into a hot seat: Role of DNA structural features on IS5-mediated gene activation and inactivation under stress. PLoS One. 2017; 12(6):e0180156. PMID: 28666002.
      View in: PubMed
    8. Rodionova IA, Zhang Z, Mehla J, Goodacre N, Babu M, Emili A, Uetz P, Saier MH. The phosphocarrier protein HPr of the bacterial phosphotransferase system globally regulates energy metabolism by directly interacting with multiple enzymes in Escherichia coli. J Biol Chem. 2017 08 25; 292(34):14250-14257. PMID: 28634232.
      View in: PubMed
    9. Saier MH, Trevors JT. Science, Innovation and the Future of Humanity. J Mol Microbiol Biotechnol. 2017; 27(2):128-132. PMID: 28448972.
      View in: PubMed
    10. Lee J, Ghosh S, Saier MH. Comparative genomic analyses of transport proteins encoded within the red algae Chondrus crispus, Galdieria sulphuraria, and Cyanidioschyzon merolae11. J Phycol. 2017 Jun; 53(3):503-521. PMID: 28328149.
      View in: PubMed
    11. Zhang Z, Kukita C, Humayun MZ, Saier MH. Environment-directed activation of the Escherichia coliflhDC operon by transposons. Microbiology. 2017 Apr; 163(4):554-569. PMID: 28100305.
      View in: PubMed
    12. Do J, Zafar H, Saier MH. Comparative genomics of transport proteins in probiotic and pathogenic Escherichia coli and Salmonella enterica strains. Microb Pathog. 2017 Jun; 107:106-115. PMID: 28344124.
      View in: PubMed
    13. Saier MH, Kukita C, Zhang Z. Transposon-mediated directed mutation in bacteria and eukaryotes. Front Biosci (Landmark Ed). 2017 03 01; 22:1458-1468. PMID: 28199212.
      View in: PubMed
    14. Vastermark A, Driker A, Weng J, Li X, Wang J, Saier MH. Difference distance map data of alternative crystal forms of UlaA. Data Brief. 2017 Feb; 10:198-201. PMID: 27995154.
      View in: PubMed
    15. Chou A, Lee A, Hendargo KJ, Reddy VS, Shlykov MA, Kuppusamykrishnan H, Medrano-Soto A, Saier MH. Characterization of the Tetraspan Junctional Complex (4JC) superfamily. Biochim Biophys Acta. 2017 Mar; 1859(3):402-414. PMID: 27916633.
      View in: PubMed
    16. Zhang Z, Saier MH. Transposon-mediated activation of the Escherichia coli glpFK operon is inhibited by specific DNA-binding proteins: Implications for stress-induced transposition events. Mutat Res. 2016 Nov - Dec; 793-794:22-31. PMID: 27810619.
      View in: PubMed
    17. Vastermark A, Driker A, Weng J, Li X, Wang J, Saier MH. The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism. J Struct Biol. 2016 12; 196(3):496-502. PMID: 27720943.
      View in: PubMed
    18. Kuppusamykrishnan H, Chau LM, Moreno-Hagelsieb G, Saier MH. Analysis of 58 Families of Holins Using a Novel Program, PhyST. J Mol Microbiol Biotechnol. 2016; 26(6):381-388. PMID: 27553295.
      View in: PubMed
    19. Buyuktimkin B, Saier MH. Comparative analyses of transport proteins encoded within the genomes of Leptospira species. Microb Pathog. 2016 Sep; 98:118-31. PMID: 27296707.
      View in: PubMed
    20. Vastermark A, Saier MH. Time to Stop Holding the Elevator: A New Piece of the Transport Protein Mechanism Puzzle. Structure. 2016 06 07; 24(6):845-6. PMID: 27276425.
      View in: PubMed
    21. Saier MH. Transport protein evolution deduced from analysis of sequence, topology and structure. Curr Opin Struct Biol. 2016 06; 38:9-17. PMID: 27270239.
      View in: PubMed
    22. Reddy BL, Saier MH. Properties and Phylogeny of 76 Families of Bacterial and Eukaryotic Organellar Outer Membrane Pore-Forming Proteins. PLoS One. 2016; 11(4):e0152733. PMID: 27064789; PMCID: PMC4827864.
    23. Saier MH, Reddy VS, Tsu BV, Ahmed MS, Li C, Moreno-Hagelsieb G. The Transporter Classification Database (TCDB): recent advances. Nucleic Acids Res. 2016 Jan 04; 44(D1):D372-9. PMID: 26546518; PMCID: PMC4702804.
    24. Zhu C, Nigam KB, Date RC, Bush KT, Springer SA, Saier MH, Wu W, Nigam SK. Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs. PLoS One. 2015; 10(11):e0140569. PMID: 26536134.
      View in: PubMed
    25. Tsu BV, Saier MH. The LysE Superfamily of Transport Proteins Involved in Cell Physiology and Pathogenesis. PLoS One. 2015; 10(10):e0137184. PMID: 26474485; PMCID: PMC4608589.
    26. Buyuktimkin B, Saier MH. Comparative genomic analyses of transport proteins encoded within the genomes of Leptospira species. Microb Pathog. 2015 Nov; 88:52-64. PMID: 26247102; PMCID: PMC4601928 [Available on 11/01/16].
    27. Babbitt PC, Bagos PG, Bairoch A, Bateman A, Chatonnet A, Chen MJ, Craik DJ, Finn RD, Gloriam D, Haft DH, Henrissat B, Holliday GL, Isberg V, Kaas Q, Landsman D, Lenfant N, Manning G, Nagano N, Srinivasan N, O'Donovan C, Pruitt KD, Sowdhamini R, Rawlings ND, Saier MH, Sharman JL, Spedding M, Tsirigos KD, Vastermark A, Vriend G. Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat. Database (Oxford). 2015; 2015:bav063. PMID: 26284514; PMCID: PMC4499208.
    28. Saier MH, Zhang Z. Control of Transposon-Mediated Directed Mutation by the Escherichia coli Phosphoenolpyruvate:Sugar Phosphotransferase System. J Mol Microbiol Biotechnol. 2015; 25(2-3):226-33. PMID: 26159081; PMCID: PMC4511099.
    29. Saier MH. The Bacterial Phosphotransferase System: New Frontiers 50 Years after Its Discovery. J Mol Microbiol Biotechnol. 2015; 25(2-3):73-8. PMID: 26159069; PMCID: PMC4512285.
    30. Holliday GL, Bairoch A, Bagos PG, Chatonnet A, Craik DJ, Finn RD, Henrissat B, Landsman D, Manning G, Nagano N, O'Donovan C, Pruitt KD, Rawlings ND, Saier M, Sowdhamini R, Spedding M, Srinivasan N, Vriend G, Babbitt PC, Bateman A. Key challenges for the creation and maintenance of specialist protein resources. Proteins. 2015 Jun; 83(6):1005-13. PMID: 25820941.
      View in: PubMed
    31. Reddy BL, Saier MH. Autism and our intestinal microbiota. J Mol Microbiol Biotechnol. 2015; 25(1):51-5. PMID: 25792275.
      View in: PubMed
    32. Västermark Å, Driker A, Li J, Saier MH. Conserved movement of TMS11 between occluded conformations of LacY and XylE of the major facilitator superfamily suggests a similar hinge-like mechanism. Proteins. 2015 Apr; 83(4):735-45. PMID: 25586173; PMCID: PMC4368487.
    33. Chiang Z, Vastermark A, Punta M, Coggill PC, Mistry J, Finn RD, Saier MH. The complexity, challenges and benefits of comparing two transporter classification systems in TCDB and Pfam. Brief Bioinform. 2015 Sep; 16(5):865-72. PMID: 25614388; PMCID: PMC4570203.
    34. Kumar U, Saier MH. Comparative genomic analysis of integral membrane transport proteins in ciliates. J Eukaryot Microbiol. 2015 Mar-Apr; 62(2):167-87. PMID: 25099884.
      View in: PubMed
    35. Tang F, Reddy BL, Saier MH. Psychobiotics and their involvement in mental health. J Mol Microbiol Biotechnol. 2014; 24(4):211-4. PMID: 25196442.
      View in: PubMed
    36. Saier MH, Reddy BL. Holins in bacteria, eukaryotes, and archaea: multifunctional xenologues with potential biotechnological and biomedical applications. J Bacteriol. 2015 Jan 01; 197(1):7-17. PMID: 25157079; PMCID: PMC4288690.
    37. Saier MH, Zhang Z. Transposon-mediated directed mutation controlled by DNA binding proteins in Escherichia coli. Front Microbiol. 2014; 5:390. PMID: 25136335; PMCID: PMC4117983.
    38. Vastermark A, Wollwage S, Houle ME, Rio R, Saier MH. Expansion of the APC superfamily of secondary carriers. Proteins. 2014 Oct; 82(10):2797-811. PMID: 25043943; PMCID: PMC4177346.
    39. Reddy A, Cho J, Ling S, Reddy V, Shlykov M, Saier MH. Reliability of nine programs of topological predictions and their application to integral membrane channel and carrier proteins. J Mol Microbiol Biotechnol. 2014; 24(3):161-90. PMID: 24992992; PMCID: PMC4125430.
    40. Zhang Z, Aboulwafa M, Saier MH. Regulation of crp gene expression by the catabolite repressor/activator, Cra, in Escherichia coli. J Mol Microbiol Biotechnol. 2014; 24(3):135-41. PMID: 24923415; PMCID: PMC4125524.
    41. Lee A, Vastermark A, Saier MH. Establishing homology between mitochondrial calcium uniporters, prokaryotic magnesium channels and chlamydial IncA proteins. Microbiology. 2014 Aug; 160(Pt 8):1679-89. PMID: 24869855; PMCID: PMC4117221.
    42. Tang F, Saier MH. Transport proteins promoting Escherichia coli pathogenesis. Microb Pathog. 2014 Jun-Jul; 71-72:41-55. PMID: 24747185; PMCID: PMC4106412.
    43. Västermark A, Lunt B, Saier M. Major facilitator superfamily porters, LacY, FucP and XylE of Escherichia coli appear to have evolved positionally dissimilar catalytic residues without rearrangement of 3-TMS repeat units. J Mol Microbiol Biotechnol. 2014; 24(2):82-90. PMID: 24603210; PMCID: PMC4048653.
    44. Västermark A, Saier MH. Major Facilitator Superfamily (MFS) evolved without 3-transmembrane segment unit rearrangements. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):E1162-3. PMID: 24567407; PMCID: PMC3977298.
    45. Västermark A, Saier MH. The involvement of transport proteins in transcriptional and metabolic regulation. Curr Opin Microbiol. 2014 Apr; 18:8-15. PMID: 24513656; PMCID: PMC3999241.
    46. Zhang K, Huentelman MJ, Rao F, Sun EI, Corneveaux JJ, Schork AJ, Wei Z, Waalen J, Miramontes-Gonzalez JP, Hightower CM, Maihofer AX, Mahata M, Pastinen T, Ehret GB. Genetic implication of a novel thiamine transporter in human hypertension. J Am Coll Cardiol. 2014 Apr 22; 63(15):1542-55. PMID: 24509276; PMCID: PMC3992204.
    47. Getsin I, Nalbandian GH, Yee DC, Vastermark A, Paparoditis PC, Reddy VS, Saier MH. Comparative genomics of transport proteins in developmental bacteria: Myxococcus xanthus and Streptomyces coelicolor. BMC Microbiol. 2013 Dec 05; 13:279. PMID: 24304716; PMCID: PMC3924187.
    48. Saier MH, Reddy VS, Tamang DG, Västermark A. The transporter classification database. Nucleic Acids Res. 2014 Jan; 42(Database issue):D251-8. PMID: 24225317; PMCID: PMC3964967.
    49. Västermark Å, Saier MH. Evolutionary relationship between 5+5 and 7+7 inverted repeat folds within the amino acid-polyamine-organocation superfamily. Proteins. 2014 Feb; 82(2):336-46. PMID: 24038584.
      View in: PubMed
    50. Yee DC, Shlykov MA, Västermark A, Reddy VS, Arora S, Sun EI, Saier MH. The transporter-opsin-G protein-coupled receptor (TOG) superfamily. FEBS J. 2013 Nov; 280(22):5780-800. PMID: 23981446; PMCID: PMC3832197.
    51. Sun EI, Leyn SA, Kazanov MD, Saier MH, Novichkov PS, Rodionov DA. Comparative genomics of metabolic capacities of regulons controlled by cis-regulatory RNA motifs in bacteria. BMC Genomics. 2013 Sep 02; 14:597. PMID: 24060102; PMCID: PMC3766115.
    52. Aboulwafa M, Saier MH. Lipid dependencies, biogenesis and cytoplasmic micellar forms of integral membrane sugar transport proteins of the bacterial phosphotransferase system. Microbiology. 2013 Nov; 159(Pt 11):2213-24. PMID: 23985145; PMCID: PMC3836488.
    53. Paparoditis P, Västermark A, Le AJ, Fuerst JA, Saier MH. Bioinformatic analyses of integral membrane transport proteins encoded within the genome of the planctomycetes species, Rhodopirellula baltica. Biochim Biophys Acta. 2014 Jan; 1838(1 Pt B):193-215. PMID: 23969110; PMCID: PMC3905805.
    54. Saier MH. Microcompartments and protein machines in prokaryotes. J Mol Microbiol Biotechnol. 2013; 23(4-5):243-69. PMID: 23920489; PMCID: PMC3832201.
    55. Reddy BL, Saier MH. Topological and phylogenetic analyses of bacterial holin families and superfamilies. Biochim Biophys Acta. 2013 Nov; 1828(11):2654-71. PMID: 23856191; PMCID: PMC3788059.
    56. Zheng WH, Västermark Å, Shlykov MA, Reddy V, Sun EI, Saier MH. Evolutionary relationships of ATP-Binding Cassette (ABC) uptake porters. BMC Microbiol. 2013 May 06; 13:98. PMID: 23647830; PMCID: PMC3654945.
    57. Saier MH, Bogdanov MV. Membranous organelles in bacteria. J Mol Microbiol Biotechnol. 2013; 23(1-2):5-12. PMID: 23615191.
      View in: PubMed
    58. Bogdanov M, Aboulwafa M, Saier MH. Subcellular localization and logistics of integral membrane protein biogenesis in Escherichia coli. J Mol Microbiol Biotechnol. 2013; 23(1-2):24-34. PMID: 23615193.
      View in: PubMed
    59. Lopez-de Los Santos Y, Chan H, Cantu VA, Rettner R, Sanchez F, Zhang Z, Saier MH, Soberon X. Genetic engineering of the phosphocarrier protein NPr of the Escherichia coli phosphotransferase system selectively improves sugar uptake activity. J Biol Chem. 2012 Aug 24; 287(35):29931-9. PMID: 22767600; PMCID: PMC3436175.
    60. Trevors JT, Pollack GH, Saier MH, Masson L. Transformative research: definitions, approaches and consequences. Theory Biosci. 2012 Jun; 131(2):117-23. PMID: 22628127; PMCID: PMC3990254.
    61. Wong FH, Chen JS, Reddy V, Day JL, Shlykov MA, Wakabayashi ST, Saier MH. The amino acid-polyamine-organocation superfamily. J Mol Microbiol Biotechnol. 2012; 22(2):105-13. PMID: 22627175.
      View in: PubMed
    62. Reddy VS, Saier MH. BioV Suite--a collection of programs for the study of transport protein evolution. FEBS J. 2012 Jun; 279(11):2036-46. PMID: 22568782; PMCID: PMC3978091.
    63. Reddy VS, Shlykov MA, Castillo R, Sun EI, Saier MH. The major facilitator superfamily (MFS) revisited. FEBS J. 2012 Jun; 279(11):2022-35. PMID: 22458847; PMCID: PMC3425384.
    64. Chen JS, Reddy V, Chen JH, Shlykov MA, Zheng WH, Cho J, Yen MR, Saier MH. Phylogenetic characterization of transport protein superfamilies: superiority of SuperfamilyTree programs over those based on multiple alignments. J Mol Microbiol Biotechnol. 2011; 21(3-4):83-96. PMID: 22286036; PMCID: PMC3290041.
    65. Zhang Z, Saier MH. Transposon-mediated adaptive and directed mutations and their potential evolutionary benefits. J Mol Microbiol Biotechnol. 2011; 21(1-2):59-70. PMID: 22248543; PMCID: PMC3697268.
    66. Saier MH. Did adaptive and directed mutation evolve to accelerate stress-induced evolutionary change? J Mol Microbiol Biotechnol. 2011; 21(1-2):5-7. PMID: 22248538.
      View in: PubMed
    67. Shlykov MA, Zheng WH, Chen JS, Saier MH. Bioinformatic characterization of the 4-Toluene Sulfonate Uptake Permease (TSUP) family of transmembrane proteins. Biochim Biophys Acta. 2012 Mar; 1818(3):703-17. PMID: 22192777; PMCID: PMC3917603.
    68. Youm J, Saier MH. Comparative analyses of transport proteins encoded within the genomes of Mycobacterium tuberculosis and Mycobacterium leprae. Biochim Biophys Acta. 2012 Mar; 1818(3):776-97. PMID: 22179038; PMCID: PMC3425379.
    69. Coyne RS, Hannick L, Shanmugam D, Hostetler JB, Brami D, Joardar VS, Johnson J, Radune D, Singh I, Badger JH, Kumar U, Saier M, Wang Y, Cai H, Gu J, Mather MW, Vaidya AB, Wilkes DE, Rajagopalan V, Asai DJ, Pearson CG, Findly RC, Dickerson HW, Wu M, Martens C, Van de Peer Y, Roos DS, Cassidy-Hanley DM, Clark TG. Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome Biol. 2011 Oct 17; 12(10):R100. PMID: 22004680; PMCID: PMC3341644.
    70. Aboulwafa M, Saier MH. Biophysical studies of the membrane-embedded and cytoplasmic forms of the glucose-specific Enzyme II of the E. coli phosphotransferase system (PTS). PLoS One. 2011; 6(9):e24088. PMID: 21935376; PMCID: PMC3174158.
    71. Sehgal AK, Das S, Noto K, Saier MH, Elkan C. Identifying relevant data for a biological database: handcrafted rules versus machine learning. IEEE/ACM Trans Comput Biol Bioinform. 2011 May-Jun; 8(3):851-7. PMID: 21393656; PMCID: PMC3980937.
    72. Silverio AL, Saier MH. Bioinformatic characterization of the trimeric intracellular cation-specific channel protein family. J Membr Biol. 2011 May; 241(2):77-101. PMID: 21519847; PMCID: PMC3980945.
    73. Gomolplitinant KM, Saier MH. Evolution of the oligopeptide transporter family. J Membr Biol. 2011 Mar; 240(2):89-110. PMID: 21347612; PMCID: PMC3061005.
    74. Trevors JT, Saier MH. A Vaccine Against Ignorance? Water Air Soil Pollut. 2011 Sep; 220(1-4):1-3. PMID: 21949450.
      View in: PubMed
    75. Lam VH, Lee JH, Silverio A, Chan H, Gomolplitinant KM, Povolotsky TL, Orlova E, Sun EI, Welliver CH, Saier MH. Pathways of transport protein evolution: recent advances. Biol Chem. 2011 Jan; 392(1-2):5-12. PMID: 21194372; PMCID: PMC4008129.
    76. Trevors JT, Saier MH. Thermodynamic perspectives on genetic instructions, the laws of biology and diseased states. C R Biol. 2011 Jan; 334(1):1-5. PMID: 21262480; PMCID: PMC4092032.
    77. Tsai JC, Yen MR, Castillo R, Leyton DL, Henderson IR, Saier MH. The bacterial intimins and invasins: a large and novel family of secreted proteins. PLoS One. 2010 Dec 22; 5(12):e14403. PMID: 21203509; PMCID: PMC3008723.
    78. Chan H, Babayan V, Blyumin E, Gandhi C, Hak K, Harake D, Kumar K, Lee P, Li TT, Liu HY, Lo TC, Meyer CJ, Stanford S, Zamora KS, Saier MH. The p-type ATPase superfamily. J Mol Microbiol Biotechnol. 2010; 19(1-2):5-104. PMID: 20962537.
      View in: PubMed
    79. Castillo R, Saier MH. Functional Promiscuity of Homologues of the Bacterial ArsA ATPases. Int J Microbiol. 2010; 2010:187373. PMID: 20981284; PMCID: PMC2963123.
    80. Trevors JT, Saier MH. The Legacy of Oil Spills. Water Air Soil Pollut. 2010 Sep; 211(1-4):1-3. PMID: 20835295.
      View in: PubMed
    81. Povolotsky TL, Orlova E, Tamang DG, Saier MH. Defense against cannibalism: the SdpI family of bacterial immunity/signal transduction proteins. J Membr Biol. 2010 Jun; 235(3):145-62. PMID: 20563570; PMCID: PMC2910880.
    82. Rettner RE, Saier MH. The autoinducer-2 exporter superfamily. J Mol Microbiol Biotechnol. 2010; 18(4):195-205. PMID: 20559013; PMCID: PMC3004238.
    83. Matias MG, Gomolplitinant KM, Tamang DG, Saier MH. Animal Ca2+ release-activated Ca2+ (CRAC) channels appear to be homologous to and derived from the ubiquitous cation diffusion facilitators. BMC Res Notes. 2010 Jun 03; 3:158. PMID: 20525303; PMCID: PMC2894845.
    84. Choi SK, Saier MH. Transcriptional Regulation of the rsbV Promoter Controlling Stress Responses to Ethanol, Carbon Limitation, and Phosphorous Limitation in Bacillus subtilis. Int J Microbiol. 2010; 2010:263410. PMID: 20454630; PMCID: PMC2862951.
    85. Pietack N, Becher D, Schmidl SR, Saier MH, Hecker M, Commichau FM, Stülke J. In vitro phosphorylation of key metabolic enzymes from Bacillus subtilis: PrkC phosphorylates enzymes from different branches of basic metabolism. J Mol Microbiol Biotechnol. 2010; 18(3):129-40. PMID: 20389117.
      View in: PubMed
    86. Xiao AY, Wang J, Saier MH. Bacterial Adaptor Membrane Fusion Proteins and the Structurally Dissimilar Outer Membrane Auxiliary Proteins Have Exchanged Central Domains in alpha-Proteobacteria. Int J Microbiol. 2010; 2010:589391. PMID: 20379386; PMCID: PMC2850547.
    87. Zhang Z, Yen MR, Saier MH. Precise excision of IS5 from the intergenic region between the fucPIK and the fucAO operons and mutational control of fucPIK operon expression in Escherichia coli. J Bacteriol. 2010 Apr; 192(7):2013-9. PMID: 20097855; PMCID: PMC2838058.
    88. Yen MR, Chen JS, Marquez JL, Sun EI, Saier MH. Multidrug resistance: phylogenetic characterization of superfamilies of secondary carriers that include drug exporters. Methods Mol Biol. 2010; 637:47-64. PMID: 20419429.
      View in: PubMed
    89. Trevors JT, Saier MH. Mathematics: The Basis for Quantitative Knowledge. Water Air Soil Pollut. 2010 Jun; 209(1-4):1-2. PMID: 22247578.
      View in: PubMed
    90. Trevors JT, Saier MH. Education for Humanity. Water Air Soil Pollut. 2010 Feb; 206(1-4):1-2. PMID: 22247577.
      View in: PubMed
    91. Trevors JT, Saier MH. Global Pollution: How Much Is Too Much? Water Air Soil Pollut. 2009 Nov; 204(1-4):1-3. PMID: 19898672.
      View in: PubMed
    92. Zhang Z, Saier MH. A novel mechanism of transposon-mediated gene activation. PLoS Genet. 2009 Oct; 5(10):e1000689. PMID: 19834539; PMCID: PMC2753651.
    93. Wang B, Dukarevich M, Sun EI, Yen MR, Saier MH. Membrane porters of ATP-binding cassette transport systems are polyphyletic. J Membr Biol. 2009 Sep; 231(1):1-10. PMID: 19806386.
      View in: PubMed
    94. Yen MR, Choi J, Saier MH. Bioinformatic analyses of transmembrane transport: novel software for deducing protein phylogeny, topology, and evolution. J Mol Microbiol Biotechnol. 2009; 17(4):163-76. PMID: 19776645; PMCID: PMC2814153.
    95. Saier MH, Trevors JT. Survival of the Fattest. Water Air Soil Pollut. 2009 Aug 20; 205(Suppl 1):107-109. PMID: 20157349.
      View in: PubMed
    96. Zhang Z, Saier MH. A mechanism of transposon-mediated directed mutation. Mol Microbiol. 2009 Oct; 74(1):29-43. PMID: 19682247; PMCID: PMC2973706.
    97. Thever MD, Saier MH. Bioinformatic characterization of p-type ATPases encoded within the fully sequenced genomes of 26 eukaryotes. J Membr Biol. 2009 Jun; 229(3):115-30. PMID: 19548020; PMCID: PMC2709905.
    98. Tamang DG, Rabus R, Barabote RD, Saier MH. Comprehensive analyses of transport proteins encoded within the genome of "Aromatoleum aromaticum" strain EbN1. J Membr Biol. 2009 May; 229(2):53-90. PMID: 19506936.
      View in: PubMed
    99. Saier MH, Yen MR, Noto K, Tamang DG, Elkan C. The Transporter Classification Database: recent advances. Nucleic Acids Res. 2009 Jan; 37(Database issue):D274-8. PMID: 19022853; PMCID: PMC2686586.
    100. Podar M, Anderson I, Makarova KS, Elkins JG, Ivanova N, Wall MA, Lykidis A, Mavromatis K, Sun H, Hudson ME, Chen W, Deciu C, Hutchison D, Eads JR, Anderson A, Fernandes F, Szeto E, Lapidus A, Kyrpides NC, Saier MH, Richardson PM, Rachel R, Huber H, Eisen JA, Koonin EV, Keller M, Stetter KO. A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome Biol. 2008; 9(11):R158. PMID: 19000309; PMCID: PMC2614490.
    101. Amar P, Legent G, Thellier M, Ripoll C, Bernot G, Nystrom T, Saier MH, Norris V. A stochastic automaton shows how enzyme assemblies may contribute to metabolic efficiency. BMC Syst Biol. 2008 Mar 25; 2:27. PMID: 18366733; PMCID: PMC2322945.
    102. Saier MH. The bacterial chromosome. Crit Rev Biochem Mol Biol. 2008 Mar-Apr; 43(2):89-134. PMID: 18365861.
      View in: PubMed
    103. Aboulwafa M, Saier MH. Characterization of the E. coli glucose permease fused to the maltose-binding protein. J Basic Microbiol. 2008 Feb; 48(1):3-9. PMID: 18247392.
      View in: PubMed
    104. Saier MH, Ma CH, Rodgers L, Tamang DG, Yen MR. Protein secretion and membrane insertion systems in bacteria and eukaryotic organelles. Adv Appl Microbiol. 2008; 65:141-97. PMID: 19026865.
      View in: PubMed
    105. Chen DE, Podell S, Sauer JD, Swanson MS, Saier MH. The phagosomal nutrient transporter (Pht) family. Microbiology. 2008 Jan; 154(Pt 1):42-53. PMID: 18174124.
      View in: PubMed
    106. Barabote RD, Rendulic S, Schuster SC, Saier MH. Comprehensive analysis of transport proteins encoded within the genome of Bdellovibrio bacteriovorus. Genomics. 2007 Oct; 90(4):424-46. PMID: 17706914; PMCID: PMC3415317.
    107. Gutierrez-Ríos RM, Freyre-Gonzalez JA, Resendis O, Collado-Vides J, Saier M, Gosset G. Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli. BMC Microbiol. 2007 Jun 08; 7:53. PMID: 17559662; PMCID: PMC1905917.
    108. Saier MH. Protein secretion and membrane insertion systems in gram-negative bacteria. J Membr Biol. 2006; 214(2):75-90. PMID: 17546510.
      View in: PubMed
    109. Lee JH, Harvat EM, Stevens JM, Ferguson SJ, Saier MH. Evolutionary origins of members of a superfamily of integral membrane cytochrome c biogenesis proteins. Biochim Biophys Acta. 2007 Sep; 1768(9):2164-81. PMID: 17706591.
      View in: PubMed
    110. Zhang Z, Ma C, Pornillos O, Xiu X, Chang G, Saier MH. Functional characterization of the heterooligomeric EbrAB multidrug efflux transporter of Bacillus subtilis. Biochemistry. 2007 May 01; 46(17):5218-25. PMID: 17417881.
      View in: PubMed
    111. Kuhlman T, Zhang Z, Saier MH, Hwa T. Combinatorial transcriptional control of the lactose operon of Escherichia coli. Proc Natl Acad Sci U S A. 2007 Apr 03; 104(14):6043-8. PMID: 17376875; PMCID: PMC1851613.
    112. Yen MR, Saier MH. Gap junctional proteins of animals: the innexin/pannexin superfamily. Prog Biophys Mol Biol. 2007 May-Jun; 94(1-2):5-14. PMID: 17507077; PMCID: PMC2592087.
    113. Norris V, den Blaauwen T, Cabin-Flaman A, Doi RH, Harshey R, Janniere L, Jimenez-Sanchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Saier M, Skarstad K. Functional taxonomy of bacterial hyperstructures. Microbiol Mol Biol Rev. 2007 Mar; 71(1):230-53. PMID: 17347523; PMCID: PMC1847379.
    114. Lorca GL, Barabote RD, Zlotopolski V, Tran C, Winnen B, Hvorup RN, Stonestrom AJ, Nguyen E, Huang LW, Kim DS, Saier MH. Transport capabilities of eleven gram-positive bacteria: comparative genomic analyses. Biochim Biophys Acta. 2007 Jun; 1768(6):1342-66. PMID: 17490609; PMCID: PMC2592090.
    115. Mansour NM, Sawhney M, Tamang DG, Vogl C, Saier MH. The bile/arsenite/riboflavin transporter (BART) superfamily. FEBS J. 2007 Feb; 274(3):612-29. PMID: 17288550.
      View in: PubMed
    116. Aboulwafa M, Saier MH. In vitro interconversion of the soluble and membrane- integrated forms of the Escherichia coli glucose enzyme II of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system. J Mol Microbiol Biotechnol. 2007; 12(3-4):263-8. PMID: 17587874.
      View in: PubMed
    117. Norris V, den Blaauwen T, Doi RH, Harshey RM, Janniere L, Jiménez-Sánchez A, Jin DJ, Levin PA, Mileykovskaya E, Minsky A, Misevic G, Ripoll C, Saier M, Skarstad K, Thellier M. Toward a hyperstructure taxonomy. Annu Rev Microbiol. 2007; 61:309-29. PMID: 17896876.
      View in: PubMed
    118. Saier MH. Active transport in communication, protection and nutrition. J Mol Microbiol Biotechnol. 2007; 12(3-4):161-4. PMID: 17587865.
      View in: PubMed
    119. Makarova K, Slesarev A, Wolf Y, Sorokin A, Mirkin B, Koonin E, Pavlov A, Pavlova N, Karamychev V, Polouchine N, Shakhova V, Grigoriev I, Lou Y, Rohksar D, Lucas S, Huang K, Goodstein DM, Hawkins T, Plengvidhya V, Welker D, Hughes J, Goh Y, Benson A, Baldwin K, Lee JH, Díaz-Muñiz I, Dosti B, Smeianov V, Wechter W, Barabote R, Lorca G, Altermann E, Barrangou R, Ganesan B, Xie Y, Rawsthorne H, Tamir D, Parker C, Breidt F, Broadbent J, Hutkins R, O'Sullivan D, Steele J, Unlu G, Saier M, Klaenhammer T, Richardson P, Kozyavkin S, Weimer B, Mills D. Comparative genomics of the lactic acid bacteria. Proc Natl Acad Sci U S A. 2006 Oct 17; 103(42):15611-6. PMID: 17030793; PMCID: PMC1622870.
    120. Kim DS, Chao Y, Saier MH. Protein-translocating trimeric autotransporters of gram-negative bacteria. J Bacteriol. 2006 Aug; 188(16):5655-67. PMID: 16885434; PMCID: PMC1540064.
    121. Barabote RD, Tamang DG, Abeywardena SN, Fallah NS, Fu JY, Lio JK, Mirhosseini P, Pezeshk R, Podell S, Salampessy ML, Thever MD, Saier MH. Extra domains in secondary transport carriers and channel proteins. Biochim Biophys Acta. 2006 Oct; 1758(10):1557-79. PMID: 16905115.
      View in: PubMed
    122. Au KM, Barabote RD, Hu KY, Saier MH. Evolutionary appearance of H+-translocating pyrophosphatases. Microbiology. 2006 May; 152(Pt 5):1243-7. PMID: 16622041.
      View in: PubMed
    123. Saier MH, Tran CV, Barabote RD. TCDB: the Transporter Classification Database for membrane transport protein analyses and information. Nucleic Acids Res. 2006 Jan 01; 34(Database issue):D181-6. PMID: 16381841; PMCID: PMC1334385.
    124. Nguyen TX, Yen MR, Barabote RD, Saier MH. Topological predictions for integral membrane permeases of the phosphoenolpyruvate:sugar phosphotransferase system. J Mol Microbiol Biotechnol. 2006; 11(6):345-60. PMID: 17114898.
      View in: PubMed
    125. Debut AJ, Dumay QC, Barabote RD, Saier MH. The iron/lead transporter superfamily of Fe/Pb2+ uptake systems. J Mol Microbiol Biotechnol. 2006; 11(1-2):1-9. PMID: 16825785.
      View in: PubMed
    126. Saier MH, Ren Q. The bioinformatic study of transmembrane molecular transport. J Mol Microbiol Biotechnol. 2006; 11(6):289-90. PMID: 17114892.
      View in: PubMed
    127. Soberón X, Saier MH. Engineering transport protein function: theoretical and technical considerations using the sugar-transporting phosphotransferase system of Escherichia coli as a model system. J Mol Microbiol Biotechnol. 2006; 11(6):302-7. PMID: 17114894.
      View in: PubMed
    128. Dumay QC, Debut AJ, Mansour NM, Saier MH. The copper transporter (Ctr) family of Cu+ uptake systems. J Mol Microbiol Biotechnol. 2006; 11(1-2):10-9. PMID: 16825786.
      View in: PubMed
    129. Tamang DG, Saier MH. The cecropin superfamily of toxic peptides. J Mol Microbiol Biotechnol. 2006; 11(1-2):94-103. PMID: 16825792.
      View in: PubMed
    130. Choi SK, Saier MH. Mechanism of CcpA-mediated glucose repression of the resABCDE operon of Bacillus subtilis. J Mol Microbiol Biotechnol. 2006; 11(1-2):104-10. PMID: 16825793.
      View in: PubMed
    131. Barabote RD, Saier MH. Comparative genomic analyses of the bacterial phosphotransferase system. Microbiol Mol Biol Rev. 2005 Dec; 69(4):608-34. PMID: 16339738; PMCID: PMC1306802.
    132. Lorca GL, Chung YJ, Barabote RD, Weyler W, Schilling CH, Saier MH. Catabolite repression and activation in Bacillus subtilis: dependency on CcpA, HPr, and HprK. J Bacteriol. 2005 Nov; 187(22):7826-39. PMID: 16267306; PMCID: PMC1280314.
    133. Choi SK, Saier MH. Regulation of sigL expression by the catabolite control protein CcpA involves a roadblock mechanism in Bacillus subtilis: potential connection between carbon and nitrogen metabolism. J Bacteriol. 2005 Oct; 187(19):6856-61. PMID: 16166551; PMCID: PMC1251575.
    134. Hagen AR, Barabote RD, Saier MH. The bestrophin family of anion channels: identification of prokaryotic homologues. Mol Membr Biol. 2005 Jul-Aug; 22(4):291-302. PMID: 16154901.
      View in: PubMed
    135. Zhang Z, Gosset G, Barabote R, Gonzalez CS, Cuevas WA, Saier MH. Functional interactions between the carbon and iron utilization regulators, Crp and Fur, in Escherichia coli. J Bacteriol. 2005 Feb; 187(3):980-90. PMID: 15659676; PMCID: PMC545712.
    136. Saier MH, Hvorup RN, Barabote RD. Evolution of the bacterial phosphotransferase system: from carriers and enzymes to group translocators. Biochem Soc Trans. 2005 Feb; 33(Pt 1):220-4. PMID: 15667312.
      View in: PubMed
    137. Stonestrom A, Barabote RD, Gonzalez CF, Saier MH. Bioinformatic analyses of bacterial HPr kinase/phosphorylase homologues. Res Microbiol. 2005 Apr; 156(3):443-51. PMID: 15808949.
      View in: PubMed
    138. Harvat EM, Zhang YM, Tran CV, Zhang Z, Frank MW, Rock CO, Saier MH. Lysophospholipid flipping across the Escherichia coli inner membrane catalyzed by a transporter (LplT) belonging to the major facilitator superfamily. J Biol Chem. 2005 Mar 25; 280(12):12028-34. PMID: 15661733.
      View in: PubMed
    139. Gonzalez CF, Stonestrom AJ, Lorca GL, Saier MH. Biochemical characterization of phosphoryl transfer involving HPr of the phosphoenolpyruvate-dependent phosphotransferase system in Treponema denticola, an organism that lacks PTS permeases. Biochemistry. 2005 Jan 18; 44(2):598-608. PMID: 15641785.
      View in: PubMed
    140. Choi SK, Saier MH. Regulation of pho regulon gene expression by the carbon control protein A, CcpA, in Bacillus subtilis. J Mol Microbiol Biotechnol. 2005; 10(1):40-50. PMID: 16491025.
      View in: PubMed
    141. Deutscher J, Saier MH. Ser/Thr/Tyr protein phosphorylation in bacteria - for long time neglected, now well established. J Mol Microbiol Biotechnol. 2005; 9(3-4):125-31. PMID: 16415586.
      View in: PubMed
    142. Cabin-Flaman A, Ripoll C, Saier MH, Norris V. Hypothesis: chemotaxis in Escherichia coli results from hyper-structure dynamics. J Mol Microbiol Biotechnol. 2005; 10(1):1-14. PMID: 16491021.
      View in: PubMed
    143. Saier MH, Mansour NM. Probiotics and prebiotics in human health. J Mol Microbiol Biotechnol. 2005; 10(1):22-5. PMID: 16491023.
      View in: PubMed
    144. von Rozycki T, Nies DH, Saier MH. Genomic analyses of transport proteins in Ralstonia metallidurans. Comp Funct Genomics. 2005; 6(1-2):17-56. PMID: 18629293; PMCID: PMC2448597.
    145. Aboulwafa M, Saier MH. Characterization of soluble enzyme II complexes of the Escherichia coli phosphotransferase system. J Bacteriol. 2004 Dec; 186(24):8453-62. PMID: 15576795; PMCID: PMC532404.
    146. Khwaja M, Ma Q, Saier MH. Topological analysis of integral membrane constituents of prokaryotic ABC efflux systems. Res Microbiol. 2005 Mar; 156(2):270-7. PMID: 15748994.
      View in: PubMed
    147. Kim SH, Chang AB, Saier MH. Sequence similarity between multidrug resistance efflux pumps of the ABC and RND superfamilies. Microbiology. 2004 Aug; 150(Pt 8):2493-5. PMID: 15289545.
      View in: PubMed
    148. Busch W, Saier MH. The IUBMB-endorsed transporter classification system. Mol Biotechnol. 2004 Jul; 27(3):253-62. PMID: 15247498.
      View in: PubMed
    149. Gosset G, Zhang Z, Nayyar S, Cuevas WA, Saier MH. Transcriptome analysis of Crp-dependent catabolite control of gene expression in Escherichia coli. J Bacteriol. 2004 Jun; 186(11):3516-24. PMID: 15150239; PMCID: PMC415760.
    150. Chang AB, Lin R, Keith Studley W, Tran CV, Saier MH. Phylogeny as a guide to structure and function of membrane transport proteins. Mol Membr Biol. 2004 May-Jun; 21(3):171-81. PMID: 15204625.
      View in: PubMed
    151. Saier MH. Evolution of bacterial type III protein secretion systems. Trends Microbiol. 2004 Mar; 12(3):113-5. PMID: 15001186.
      View in: PubMed
    152. Bertram R, Schlicht M, Mahr K, Nothaft H, Saier MH, Titgemeyer F. In silico and transcriptional analysis of carbohydrate uptake systems of Streptomyces coelicolor A3(2). J Bacteriol. 2004 Mar; 186(5):1362-73. PMID: 14973030; PMCID: PMC344420.
    153. von Rozycki T, Schultzel MA, Saier MH. Sequence analyses of cyanobacterial bicarbonate transporters and their homologues. J Mol Microbiol Biotechnol. 2004; 7(3):102-8. PMID: 15263814.
      View in: PubMed
    154. Tran CV, Saier MH. The principal chloroquine resistance protein of Plasmodium falciparum is a member of the drug/metabolite transporter superfamily. Microbiology. 2004 Jan; 150(Pt 1):1-3. PMID: 14702390.
      View in: PubMed
    155. Felce J, Saier MH. Carbonic anhydrases fused to anion transporters of the SulP family: evidence for a novel type of bicarbonate transporter. J Mol Microbiol Biotechnol. 2004; 8(3):169-76. PMID: 16088218.
      View in: PubMed
    156. von Rozycki T, Yen MR, Lende EE, Saier MH. The YedZ family: possible heme binding proteins that can be fused to transporters and electron carriers. J Mol Microbiol Biotechnol. 2004; 8(3):129-40. PMID: 16088215.
      View in: PubMed
    157. Chagneau C, Saier MH. Biofilm-defective mutants of Bacillus subtilis. J Mol Microbiol Biotechnol. 2004; 8(3):177-88. PMID: 16088219.
      View in: PubMed
    158. Prakash S, Cooper G, Singhi S, Saier MH. The ion transporter superfamily. Biochim Biophys Acta. 2003 Dec 03; 1618(1):79-92. PMID: 14643936.
      View in: PubMed
    159. Aboulwafa M, Hvorup R, Saier MH. Dependency of sugar transport and phosphorylation by the phosphoenolpyruvate-dependent phosphotransferase system on membranous phosphatidylethanolamine in Escherichia coli: studies with a pssA mutant lacking phosphatidylserine synthase. Arch Microbiol. 2004 Jan; 181(1):26-34. PMID: 14634719.
      View in: PubMed
    160. Peabody CR, Chung YJ, Yen MR, Vidal-Ingigliardi D, Pugsley AP, Saier MH. Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella. Microbiology. 2003 Nov; 149(Pt 11):3051-72. PMID: 14600218.
      View in: PubMed
    161. Winnen B, Hvorup RN, Saier MH. The tripartite tricarboxylate transporter (TTT) family. Res Microbiol. 2003 Sep; 154(7):457-65. PMID: 14499931.
      View in: PubMed
    162. Zhai YF, Heijne W, Saier MH. Molecular modeling of the bacterial outer membrane receptor energizer, ExbBD/TonB, based on homology with the flagellar motor, MotAB. Biochim Biophys Acta. 2003 Aug 07; 1614(2):201-10. PMID: 12896813.
      View in: PubMed
    163. Hua VB, Chang AB, Tchieu JH, Kumar NM, Nielsen PA, Saier MH. Sequence and phylogenetic analyses of 4 TMS junctional proteins of animals: connexins, innexins, claudins and occludins. J Membr Biol. 2003 Jul 01; 194(1):59-76. PMID: 14502443.
      View in: PubMed
    164. Zhang Z, Feige JN, Chang AB, Anderson IJ, Brodianski VM, Vitreschak AG, Gelfand MS, Saier MH. A transporter of Escherichia coli specific for L- and D-methionine is the prototype for a new family within the ABC superfamily. Arch Microbiol. 2003 Aug; 180(2):88-100. PMID: 12819857.
      View in: PubMed
    165. Saier MH. Tracing pathways of transport protein evolution. Mol Microbiol. 2003 Jun; 48(5):1145-56. PMID: 12787345.
      View in: PubMed
    166. Lorca G, Winnen B, Saier MH. Identification of the L-aspartate transporter in Bacillus subtilis. J Bacteriol. 2003 May; 185(10):3218-22. PMID: 12730183; PMCID: PMC154055.
    167. Zhang Z, Aboulwafa M, Smith MH, Saier MH. The ascorbate transporter of Escherichia coli. J Bacteriol. 2003 Apr; 185(7):2243-50. PMID: 12644495; PMCID: PMC151508.
    168. Aboulwafa M, Saier M. Soluble sugar permeases of the phosphotransferase system in Escherichia coli: evidence for two physically distinct forms of the proteins in vivo. Mol Microbiol. 2003 Apr; 48(1):131-41. PMID: 12657050.
      View in: PubMed
    169. Ma Q, Zhai Y, Schneider JC, Ramseier TM, Saier MH. Protein secretion systems of Pseudomonas aeruginosa and P fluorescens. Biochim Biophys Acta. 2003 Apr 01; 1611(1-2):223-33. PMID: 12659964.
      View in: PubMed
    170. Aboulwafa M, Chung YJ, Wai HH, Saier MH. Studies on the Escherichia coli glucose-specific permease, PtsG, with a point mutation in its N-terminal amphipathic leader sequence. Microbiology. 2003 Mar; 149(Pt 3):763-71. PMID: 12634344.
      View in: PubMed
    171. Hvorup RN, Winnen B, Chang AB, Jiang Y, Zhou XF, Saier MH. The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily. Eur J Biochem. 2003 Mar; 270(5):799-813. PMID: 12603313.
      View in: PubMed
    172. Pivetti CD, Yen MR, Miller S, Busch W, Tseng YH, Booth IR, Saier MH. Two families of mechanosensitive channel proteins. Microbiol Mol Biol Rev. 2003 Mar; 67(1):66-85, table of contents. PMID: 12626684; PMCID: PMC150521.
    173. Cao TB, Saier MH. The general protein secretory pathway: phylogenetic analyses leading to evolutionary conclusions. Biochim Biophys Acta. 2003 Jan 10; 1609(1):115-25. PMID: 12507766.
      View in: PubMed
    174. Zhou X, Hvorup RN, Saier MH. An automated program to screen databases for members of protein families. J Mol Microbiol Biotechnol. 2003; 5(1):7-10. PMID: 12673056.
      View in: PubMed
    175. Zhou X, Yang NM, Tran CV, Hvorup RN, Saier MH. Web-based programs for the display and analysis of transmembrane alpha-helices in aligned protein sequences. J Mol Microbiol Biotechnol. 2003; 5(1):1-6. PMID: 12673055.
      View in: PubMed
    176. Hvorup R, Chang AB, Saier MH. Bioinformatic analyses of the bacterial L-ascorbate phosphotransferase system permease family. J Mol Microbiol Biotechnol. 2003; 6(3-4):191-205. PMID: 15153772.
      View in: PubMed
    177. Kimball RA, Martin L, Saier MH. Reversing transmembrane electron flow: the DsbD and DsbB protein families. J Mol Microbiol Biotechnol. 2003; 5(3):133-49. PMID: 12766342.
      View in: PubMed
    178. Minocha R, Studley K, Saier MH. The urea transporter (UT) family: bioinformatic analyses leading to structural, functional, and evolutionary predictions. Receptors Channels. 2003; 9(6):345-52. PMID: 14698962.
      View in: PubMed
    179. Busch W, Saier MH. The IUBMB-endorsed transporter classification system. Methods Mol Biol. 2003; 227:21-36. PMID: 12824641.
      View in: PubMed
    180. Aboulwafa M, Saier MH. Dependency of sugar transport and phosphorylation by the phosphoenolpyruvate-dependent phosphotransferase system on membranous phosphatidyl glycerol in Escherichia coli: studies with a pgsA mutant lacking phosphatidyl glycerophosphate synthase. Res Microbiol. 2002 Dec; 153(10):667-77. PMID: 12558186.
      View in: PubMed
    181. Hvorup RN, Saier MH. Sequence similarity between the channel-forming domains of voltage-gated ion channel proteins and the C-terminal domains of secondary carriers of the major facilitator superfamily. Microbiology. 2002 Dec; 148(Pt 12):3760-2. PMID: 12480878.
      View in: PubMed
    182. Greenberg DB, Stülke J, Saier MH. Domain analysis of transcriptional regulators bearing PTS regulatory domains. Res Microbiol. 2002 Oct; 153(8):519-26. PMID: 12437213.
      View in: PubMed
    183. Zhai Y, Saier MH. The beta-barrel finder (BBF) program, allowing identification of outer membrane beta-barrel proteins encoded within prokaryotic genomes. Protein Sci. 2002 Sep; 11(9):2196-207. PMID: 12192075; PMCID: PMC2373602.
    184. Hu KY, Saier MH. Phylogeny of phosphoryl transfer proteins of the phosphoenolpyruvate-dependent sugar-transporting phosphotransferase system. Res Microbiol. 2002 Sep; 153(7):405-15. PMID: 12405346.
      View in: PubMed
    185. Klaenhammer T, Altermann E, Arigoni F, Bolotin A, Breidt F, Broadbent J, Cano R, Chaillou S, Deutscher J, Gasson M, van de Guchte M, Guzzo J, Hartke A, Hawkins T, Hols P, Hutkins R, Kleerebezem M, Kok J, Kuipers O, Lubbers M, Maguin E, McKay L, Mills D, Nauta A, Overbeek R, Pel H, Pridmore D, Saier M, van Sinderen D, Sorokin A, Steele J, O'Sullivan D, de Vos W, Weimer B, Zagorec M, Siezen R. Discovering lactic acid bacteria by genomics. Antonie Van Leeuwenhoek. 2002 Aug; 82(1-4):29-58. PMID: 12369195.
      View in: PubMed
    186. Zhai Y, Saier MH. A simple sensitive program for detecting internal repeats in sets of multiply aligned homologous proteins. J Mol Microbiol Biotechnol. 2002 Jul; 4(4):375-7. PMID: 12125818.
      View in: PubMed
    187. Yen MR, Peabody CR, Partovi SM, Zhai Y, Tseng YH, Saier MH. Protein-translocating outer membrane porins of Gram-negative bacteria. Biochim Biophys Acta. 2002 May 03; 1562(1-2):6-31. PMID: 11988218.
      View in: PubMed
    188. Chung YJ, Saier MH. Overexpression of the Escherichia coli sugE gene confers resistance to a narrow range of quaternary ammonium compounds. J Bacteriol. 2002 May; 184(9):2543-5. PMID: 11948170; PMCID: PMC135002.
    189. Kinch LN, Saier MH, Grishin NV. Sec61beta--a component of the archaeal protein secretory system. Trends Biochem Sci. 2002 Apr; 27(4):170-1. PMID: 11943537.
      View in: PubMed
    190. Kimball RA, Saier MH. Voltage-gated H+ channels associated with human phagocyte superoxide-generating NADPH oxidases: sequence comparisons, structural predictions, and phylogenetic analyses. Mol Membr Biol. 2002 Apr-Jun; 19(2):137-47. PMID: 12126231.
      View in: PubMed
    191. Yen MR, Tseng YH, Nguyen EH, Wu LF, Saier MH. Sequence and phylogenetic analyses of the twin-arginine targeting (Tat) protein export system. Arch Microbiol. 2002 Jun; 177(6):441-50. PMID: 12029389.
      View in: PubMed
    192. Karp PD, Riley M, Saier M, Paulsen IT, Collado-Vides J, Paley SM, Pellegrini-Toole A, Bonavides C, Gama-Castro S. The EcoCyc Database. Nucleic Acids Res. 2002 Jan 01; 30(1):56-8. PMID: 11752253; PMCID: PMC99147.
    193. Zhai Y, Tchieu J, Saier MH. A web-based Tree View (TV) program for the visualization of phylogenetic trees. J Mol Microbiol Biotechnol. 2002 Jan; 4(1):69-70. PMID: 11763971.
      View in: PubMed
    194. Yen MR, Tseng YH, Simic P, Sahm H, Eggeling L, Saier MH. The ubiquitous ThrE family of putative transmembrane amino acid efflux transporters. Res Microbiol. 2002 Jan-Feb; 153(1):19-25. PMID: 11881894.
      View in: PubMed
    195. Saier MH, Goldman SR, Maile RR, Moreno MS, Weyler W, Yang N, Paulsen IT. Transport capabilities encoded within the Bacillus subtilis genome. J Mol Microbiol Biotechnol. 2002 Jan; 4(1):37-67. PMID: 11763970.
      View in: PubMed
    196. Quan JA, Schneider BL, Paulsen IT, Yamada M, Kredich NM, Saier MH. Regulation of carbon utilization by sulfur availability in Escherichia coli and Salmonella typhimurium. Microbiology. 2002 Jan; 148(Pt 1):123-31. PMID: 11782505.
      View in: PubMed
    197. Busch W, Saier MH. The transporter classification (TC) system, 2002. Crit Rev Biochem Mol Biol. 2002; 37(5):287-337. PMID: 12449427.
      View in: PubMed
    198. Amar P, Ballet P, Barlovatz-Meimon G, Benecke A, Bernot G, Bouligand Y, Bourguine P, Delaplace F, Delosme JM, Demarty M, Fishov I, Fourmentin-Guilbert J, Fralick J, Giavitto JL, Gleyse B, Godin C, Incitti R, Képès F, Lange C, Le Sceller L, Loutellier C, Michel O, Molina F, Monnier C, Natowicz R, Norris V, Orange N, Pollard H, Raine D, Ripoll C, Rouviere-Yaniv J, Saier M, Soler P, Tambourin P, Thellier M, Tracqui P, Ussery D, Vincent JC, Vannier JP, Wiggins P, Zemirline A. Hyperstructures, genome analysis and I-cells. Acta Biotheor. 2002; 50(4):357-73. PMID: 12675536.
      View in: PubMed
    199. Cao TB, Saier MH. Conjugal type IV macromolecular transfer systems of Gram-negative bacteria: organismal distribution, structural constraints and evolutionary conclusions. Microbiology. 2001 Dec; 147(Pt 12):3201-14. PMID: 11739753.
      View in: PubMed
    200. Yen MR, Harley KT, Tseng YH, Saier MH. Phylogenetic and structural analyses of the oxa1 family of protein translocases. FEMS Microbiol Lett. 2001 Nov 13; 204(2):223-31. PMID: 11731127.
      View in: PubMed
    201. Yen MR, Tseng YH, Saier MH. Maize Yellow Stripe1, an iron-phytosiderophore uptake transporter, is a member of the oligopeptide transporter (OPT) family. Microbiology. 2001 Nov; 147(Pt 11):2881-3. PMID: 11700339.
      View in: PubMed
    202. Zhai Y, Saier MH. A web-based program (WHAT) for the simultaneous prediction of hydropathy, amphipathicity, secondary structure and transmembrane topology for a single protein sequence. J Mol Microbiol Biotechnol. 2001 Oct; 3(4):501-2. PMID: 11545267.
      View in: PubMed
    203. Tchieu JH, Norris V, Edwards JS, Saier MH. The complete phosphotransferase system in Escherichia coli. J Mol Microbiol Biotechnol. 2001 Jul; 3(3):329-46. PMID: 11361063.
      View in: PubMed
    204. Faure D, Saier MH, Vanderleyden J. An evolutionary alternative system for aryl beta-glucosides assimilation in bacteria. J Mol Microbiol Biotechnol. 2001 Jul; 3(3):467-70. PMID: 11361080.
      View in: PubMed
    205. Saier MH. The bacterial phosphotransferase system: structure, function, regulation and evolution. J Mol Microbiol Biotechnol. 2001 Jul; 3(3):325-7. PMID: 11361062.
      View in: PubMed
    206. Jack DL, Yang NM, Saier MH. The drug/metabolite transporter superfamily. Eur J Biochem. 2001 Jul; 268(13):3620-39. PMID: 11432728.
      View in: PubMed
    207. Saier MH, Paulsen IT. Phylogeny of multidrug transporters. Semin Cell Dev Biol. 2001 Jun; 12(3):205-13. PMID: 11428913.
      View in: PubMed
    208. Ab E, Schuurman-Wolters GK, Nijlant D, Dijkstra K, Saier MH, Robillard GT, Scheek RM. NMR structure of cysteinyl-phosphorylated enzyme IIB of the N,N'-diacetylchitobiose-specific phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli. J Mol Biol. 2001 May 18; 308(5):993-1009. PMID: 11352587.
      View in: PubMed
    209. Djordjevic GM, Tchieu JH, Saier MH. Genes involved in control of galactose uptake in Lactobacillus brevis and reconstitution of the regulatory system in Bacillus subtilis. J Bacteriol. 2001 May; 183(10):3224-36. PMID: 11325952; PMCID: PMC95224.
    210. Zhai Y, Heijne WH, Smith DW, Saier MH. Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein. Biochim Biophys Acta. 2001 Apr 02; 1511(2):206-23. PMID: 11286964.
      View in: PubMed
    211. Zhai Y, Saier MH. A web-based program for the prediction of average hydropathy, average amphipathicity and average similarity of multiply aligned homologous proteins. J Mol Microbiol Biotechnol. 2001 Apr; 3(2):285-6. PMID: 11321584.
      View in: PubMed
    212. Paulsen IT, Chen J, Nelson KE, Saier MH. Comparative genomics of microbial drug efflux systems. J Mol Microbiol Biotechnol. 2001 Apr; 3(2):145-50. PMID: 11321566.
      View in: PubMed
    213. Moreno MS, Schneider BL, Maile RR, Weyler W, Saier MH. Catabolite repression mediated by the CcpA protein in Bacillus subtilis: novel modes of regulation revealed by whole-genome analyses. Mol Microbiol. 2001 Mar; 39(5):1366-81. PMID: 11251851.
      View in: PubMed
    214. Chung YJ, Saier MH. SMR-type multidrug resistance pumps. Curr Opin Drug Discov Devel. 2001 Mar; 4(2):237-45. PMID: 11378963.
      View in: PubMed
    215. Chung YJ, Krueger C, Metzgar D, Saier MH. Size comparisons among integral membrane transport protein homologues in bacteria, Archaea, and Eucarya. J Bacteriol. 2001 Feb; 183(3):1012-21. PMID: 11208800; PMCID: PMC94969.
    216. Saier MH. Evolution of transport proteins. Genet Eng (N Y). 2001; 23:1-10. PMID: 11570098.
      View in: PubMed
    217. Saier MH, Paulsen IT. Whole genome analyses of transporters in spirochetes: Borrelia burgdorferi and Treponema pallidum. J Mol Microbiol Biotechnol. 2000 Oct; 2(4):393-9. PMID: 11075911.
      View in: PubMed
    218. Schilling CH, Held L, Torre M, Saier MH. GRASP-DNA: a web application to screen prokaryotic genomes for specific DNA-binding sites and repeat motifs. J Mol Microbiol Biotechnol. 2000 Oct; 2(4):495-500. PMID: 11075923.
      View in: PubMed
    219. Paulsen IT, Reizer J, Jin RZ, Lin EC, Saier MH. Functional genomic studies of dihydroxyacetone utilization in Escherichia coli. Microbiology. 2000 Oct; 146 ( Pt 10):2343-4. PMID: 11021910.
      View in: PubMed
    220. Zhai Y, Saier MH. The amoebapore superfamily. Biochim Biophys Acta. 2000 Sep 18; 1469(2):87-99. PMID: 10998571.
      View in: PubMed
    221. Saier MH. Vectorial metabolism and the evolution of transport systems. J Bacteriol. 2000 Sep; 182(18):5029-35. PMID: 10960084; PMCID: PMC94648.
    222. Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature. 2000 Aug 31; 406(6799):959-64. PMID: 10984043.
      View in: PubMed
    223. Paulsen IT, Nguyen L, Sliwinski MK, Rabus R, Saier MH. Microbial genome analyses: comparative transport capabilities in eighteen prokaryotes. J Mol Biol. 2000 Aug 04; 301(1):75-100. PMID: 10926494.
      View in: PubMed
    224. Jack DL, Paulsen IT, Saier MH. The amino acid/polyamine/organocation (APC) superfamily of transporters specific for amino acids, polyamines and organocations. Microbiology. 2000 Aug; 146 ( Pt 8):1797-814. PMID: 10931886.
      View in: PubMed
    225. Saier MH. Families of transmembrane transporters selective for amino acids and their derivatives. Microbiology. 2000 Aug; 146 ( Pt 8):1775-95. PMID: 10931885.
      View in: PubMed
    226. Saier MH. A functional-phylogenetic classification system for transmembrane solute transporters. Microbiol Mol Biol Rev. 2000 Jun; 64(2):354-411. PMID: 10839820; PMCID: PMC98997.
    227. Saier MH. Families of proteins forming transmembrane channels. J Membr Biol. 2000 Jun 01; 175(3):165-80. PMID: 10833527.
      View in: PubMed
    228. Harley KT, Saier MH. A novel ubiquitous family of putative efflux transporters. J Mol Microbiol Biotechnol. 2000 Apr; 2(2):195-8. PMID: 10939244.
      View in: PubMed
    229. Jack DL, Storms ML, Tchieu JH, Paulsen IT, Saier MH. A broad-specificity multidrug efflux pump requiring a pair of homologous SMR-type proteins. J Bacteriol. 2000 Apr; 182(8):2311-3. PMID: 10735877; PMCID: PMC111283.
    230. Nguyen L, Paulsen IT, Tchieu J, Hueck CJ, Saier MH. Phylogenetic analyses of the constituents of Type III protein secretion systems. J Mol Microbiol Biotechnol. 2000 Apr; 2(2):125-44. PMID: 10939240.
      View in: PubMed
    231. Harley KT, Djordjevic GM, Tseng TT, Saier MH. Membrane-fusion protein homologues in gram-positive bacteria. Mol Microbiol. 2000 Apr; 36(2):516-7. PMID: 10792737.
      View in: PubMed
    232. Saier MH. Families of transmembrane sugar transport proteins. Mol Microbiol. 2000 Feb; 35(4):699-710. PMID: 10692148.
      View in: PubMed
    233. Karp PD, Riley M, Saier M, Paulsen IT, Paley SM, Pellegrini-Toole A. The EcoCyc and MetaCyc databases. Nucleic Acids Res. 2000 Jan 01; 28(1):56-9. PMID: 10592180; PMCID: PMC102475.
    234. Reizer J, Bachem S, Reizer A, Arnaud M, Saier MH, Stülke J. Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis. Microbiology. 1999 Dec; 145 ( Pt 12):3419-29. PMID: 10627040.
      View in: PubMed
    235. Rabus R, Jack DL, Kelly DJ, Saier MH. TRAP transporters: an ancient family of extracytoplasmic solute-receptor-dependent secondary active transporters. Microbiology. 1999 Dec; 145 ( Pt 12):3431-45. PMID: 10627041.
      View in: PubMed
    236. Verrey F, Jack DL, Paulsen IT, Saier MH, Pfeiffer R. New glycoprotein-associated amino acid transporters. J Membr Biol. 1999 Dec 01; 172(3):181-92. PMID: 10568788.
      View in: PubMed
    237. Saier MH, Beatty JT, Goffeau A, Harley KT, Heijne WH, Huang SC, Jack DL, Jähn PS, Lew K, Liu J, Pao SS, Paulsen IT, Tseng TT, Virk PS. The major facilitator superfamily. J Mol Microbiol Biotechnol. 1999 Nov; 1(2):257-79. PMID: 10943556.
      View in: PubMed
    238. Nelson RD, Kuan G, Saier MH, Montal M. Modular assembly of voltage-gated channel proteins: a sequence analysis and phylogenetic study. J Mol Microbiol Biotechnol. 1999 Nov; 1(2):281-7. PMID: 10943557.
      View in: PubMed
    239. Saier MH, Paulsen IT. Paralogous genes encoding transport proteins in microbial genomes. Res Microbiol. 1999 Nov-Dec; 150(9-10):689-99. PMID: 10673007.
      View in: PubMed
    240. Reizer J, Reizer A, Lagrou MJ, Folger KR, Stover CK, Saier MH. Novel phosphotransferase systems revealed by bacterial genome analysis: the complete repertoire of pts genes in Pseudomonas aeruginosa. J Mol Microbiol Biotechnol. 1999 Nov; 1(2):289-93. PMID: 10943558.
      View in: PubMed
    241. Vrljic M, Garg J, Bellmann A, Wachi S, Freudl R, Malecki MJ, Sahm H, Kozina VJ, Eggeling L, Saier MH, Eggeling L, Saier MH. The LysE superfamily: topology of the lysine exporter LysE of Corynebacterium glutamicum, a paradyme for a novel superfamily of transmembrane solute translocators. J Mol Microbiol Biotechnol. 1999 Nov; 1(2):327-36. PMID: 10943564.
      View in: PubMed
    242. Saier MH. Genome archeology leading to the characterization and classification of transport proteins. Curr Opin Microbiol. 1999 Oct; 2(5):555-61. PMID: 10508720.
      View in: PubMed
    243. Rabus R, Reizer J, Paulsen I, Saier MH. Enzyme I(Ntr) from Escherichia coli. A novel enzyme of the phosphoenolpyruvate-dependent phosphotransferase system exhibiting strict specificity for its phosphoryl acceptor, NPr. J Biol Chem. 1999 Sep 10; 274(37):26185-91. PMID: 10473571.
      View in: PubMed
    244. Tseng TT, Gratwick KS, Kollman J, Park D, Nies DH, Goffeau A, Saier MH. The RND permease superfamily: an ancient, ubiquitous and diverse family that includes human disease and development proteins. J Mol Microbiol Biotechnol. 1999 Aug; 1(1):107-25. PMID: 10941792.
      View in: PubMed
    245. Saier MH, Kollman JM. Is FatP a long-chain fatty acid transporter? Mol Microbiol. 1999 Aug; 33(3):670-2. PMID: 10417658.
      View in: PubMed
    246. Reizer J, Schneider B, Reizer A, Saier MH. A hybrid response regulator possessing a PEP-dependent phosphorylation domain. Microbiology. 1999 May; 145 ( Pt 5):987-9. PMID: 10376812.
      View in: PubMed
    247. Dassa E, Hofnung M, Paulsen IT, Saier MH. The Escherichia coli ABC transporters: an update. Mol Microbiol. 1999 May; 32(4):887-9. PMID: 10361292.
      View in: PubMed
    248. Le T, Tseng TT, Saier MH. Flexible programs for the prediction of average amphipathicity of multiply aligned homologous proteins: application to integral membrane transport proteins. Mol Membr Biol. 1999 Apr-Jun; 16(2):173-9. PMID: 10417982.
      View in: PubMed
    249. Youderian P, Lawes MC, Creighton C, Cook JC, Saier MH. Mutations that confer resistance to 2-deoxyglucose reduce the specific activity of hexokinase from Myxococcus xanthus. J Bacteriol. 1999 Apr; 181(7):2225-35. PMID: 10094702; PMCID: PMC93637.
    250. Norris V, Gascuel P, Guespin-Michel J, Ripoll C, Saier MH. Metabolite-induced metabolons: the activation of transporter-enzyme complexes by substrate binding. Mol Microbiol. 1999 Mar; 31(5):1592-5. PMID: 10200976.
      View in: PubMed
    251. Saier MH, Eng BH, Fard S, Garg J, Haggerty DA, Hutchinson WJ, Jack DL, Lai EC, Liu HJ, Nusinew DP, Omar AM, Pao SS, Paulsen IT, Quan JA, Sliwinski M, Tseng TT, Wachi S, Young GB. Phylogenetic characterization of novel transport protein families revealed by genome analyses. Biochim Biophys Acta. 1999 Feb 25; 1422(1):1-56. PMID: 10082980.
      View in: PubMed
    252. Young GB, Jack DL, Smith DW, Saier MH. The amino acid/auxin:proton symport permease family. Biochim Biophys Acta. 1999 Jan 08; 1415(2):306-22. PMID: 9889387.
      View in: PubMed
    253. Studley WK, Yamaguchi M, Hatefi Y, Saier MH. Phylogenetic analyses of proton-translocating transhydrogenases. Microb Comp Genomics. 1999; 4(3):173-86. PMID: 10587945.
      View in: PubMed
    254. Saier MH. A functional-phylogenetic system for the classification of transport proteins. J Cell Biochem. 1999; Suppl 32-33:84-94. PMID: 10629107.
      View in: PubMed
    255. Saier MH. Eukaryotic transmembrane solute transport systems. Int Rev Cytol. 1999; 190:61-136. PMID: 10331239.
      View in: PubMed
    256. Nies DH, Koch S, Wachi S, Peitzsch N, Saier MH. CHR, a novel family of prokaryotic proton motive force-driven transporters probably containing chromate/sulfate antiporters. J Bacteriol. 1998 Nov; 180(21):5799-802. PMID: 9791139; PMCID: PMC107648.
    257. Eng BH, Guerinot ML, Eide D, Saier MH. Sequence analyses and phylogenetic characterization of the ZIP family of metal ion transport proteins. J Membr Biol. 1998 Nov 01; 166(1):1-7. PMID: 9784581.
      View in: PubMed
    258. Garrity LF, Schiel SL, Merrill R, Reizer J, Saier MH, Ordal GW. Unique regulation of carbohydrate chemotaxis in Bacillus subtilis by the phosphoenolpyruvate-dependent phosphotransferase system and the methyl-accepting chemotaxis protein McpC. J Bacteriol. 1998 Sep; 180(17):4475-80. PMID: 9721285; PMCID: PMC107457.
    259. Saier MH. Genome sequencing and informatics: new tools for biochemical discoveries. Plant Physiol. 1998 Aug; 117(4):1129-33. PMID: 9701568; PMCID: PMC1539184.
    260. Paulsen IT, Sliwinski MK, Nelissen B, Goffeau A, Saier MH. Unified inventory of established and putative transporters encoded within the complete genome of Saccharomyces cerevisiae. FEBS Lett. 1998 Jun 23; 430(1-2):116-25. PMID: 9678606.
      View in: PubMed
    261. Bordo D, van Monfort RL, Pijning T, Kalk KH, Reizer J, Saier MH, Dijkstra BW. The three-dimensional structure of the nitrogen regulatory protein IIANtr from Escherichia coli. J Mol Biol. 1998 May 29; 279(1):245-55. PMID: 9636714.
      View in: PubMed
    262. Chen Y, Case DA, Reizer J, Saier MH, Wright PE. High-resolution solution structure of Bacillus subtilis IIAglc. Proteins. 1998 May 15; 31(3):258-70. PMID: 9593197.
      View in: PubMed
    263. Paulsen IT, Sliwinski MK, Saier MH. Microbial genome analyses: global comparisons of transport capabilities based on phylogenies, bioenergetics and substrate specificities. J Mol Biol. 1998 Apr 03; 277(3):573-92. PMID: 9533881.
      View in: PubMed
    264. Saier MH. Multiple mechanisms controlling carbon metabolism in bacteria. Biotechnol Bioeng. 1998 Apr 20-May 5; 58(2-3):170-4. PMID: 10191387.
      View in: PubMed
    265. Saier MH, Paulsen IT, Sliwinski MK, Pao SS, Skurray RA, Nikaido H. Evolutionary origins of multidrug and drug-specific efflux pumps in bacteria. FASEB J. 1998 Mar; 12(3):265-74. PMID: 9506471.
      View in: PubMed
    266. Reizer J, Hoischen C, Titgemeyer F, Rivolta C, Rabus R, Stülke J, Karamata D, Saier MH, Hillen W. A novel protein kinase that controls carbon catabolite repression in bacteria. Mol Microbiol. 1998 Mar; 27(6):1157-69. PMID: 9570401.
      View in: PubMed
    267. Pao SS, Paulsen IT, Saier MH. Major facilitator superfamily. Microbiol Mol Biol Rev. 1998 Mar; 62(1):1-34. PMID: 9529885; PMCID: PMC98904.
    268. Chauvaux S, Paulsen IT, Saier MH. CcpB, a novel transcription factor implicated in catabolite repression in Bacillus subtilis. J Bacteriol. 1998 Feb; 180(3):491-7. PMID: 9457849; PMCID: PMC106913.
    269. Paulsen IT, Chauvaux S, Choi P, Saier MH. Characterization of glucose-specific catabolite repression-resistant mutants of Bacillus subtilis: identification of a novel hexose:H+ symporter. J Bacteriol. 1998 Feb; 180(3):498-504. PMID: 9457850; PMCID: PMC106914.
    270. Saier MH. Molecular phylogeny as a basis for the classification of transport proteins from bacteria, archaea and eukarya. Adv Microb Physiol. 1998; 40:81-136. PMID: 9889977.
      View in: PubMed
    271. Rajagopal P, Waygood EB, Reizer J, Saier MH, Klevit RE. Demonstration of protein-protein interaction specificity by NMR chemical shift mapping. Protein Sci. 1997 Dec; 6(12):2624-7. PMID: 9416611; PMCID: PMC2143627.
    272. Paulsen IT, Park JH, Choi PS, Saier MH. A family of gram-negative bacterial outer membrane factors that function in the export of proteins, carbohydrates, drugs and heavy metals from gram-negative bacteria. FEMS Microbiol Lett. 1997 Nov 01; 156(1):1-8. PMID: 9368353.
      View in: PubMed
    273. Reizer J, Reizer A, Saier MH. Is the ribulose monophosphate pathway widely distributed in bacteria? Microbiology. 1997 Aug; 143 ( Pt 8):2519-20. PMID: 9274005.
      View in: PubMed
    274. Paulsen IT, Beness AM, Saier MH. Computer-based analyses of the protein constituents of transport systems catalysing export of complex carbohydrates in bacteria. Microbiology. 1997 Aug; 143 ( Pt 8):2685-99. PMID: 9274022.
      View in: PubMed
    275. Tortosa P, Aymerich S, Lindner C, Saier MH, Reizer J, Le Coq D. Multiple phosphorylation of SacY, a Bacillus subtilis transcriptional antiterminator negatively controlled by the phosphotransferase system. J Biol Chem. 1997 Jul 04; 272(27):17230-7. PMID: 9202047.
      View in: PubMed
    276. Loveless BJ, Saier MH. A novel family of channel-forming, autotransporting, bacterial virulence factors. Mol Membr Biol. 1997 Jul-Sep; 14(3):113-23. PMID: 9394291.
      View in: PubMed
    277. Reizer J, Saier MH. Modular multidomain phosphoryl transfer proteins of bacteria. Curr Opin Struct Biol. 1997 Jun; 7(3):407-15. PMID: 9204284.
      View in: PubMed
    278. Pao GM, Saier MH. Nonplastid eukaryotic response regulators have a monophyletic origin and evolved from their bacterial precursors in parallel with their cognate sensor kinases. J Mol Evol. 1997 Jun; 44(6):605-13. PMID: 9169552.
      View in: PubMed
    279. Dagnall BH, Saier MH. HatA and HatR, implicated in the uptake of inorganic carbon in Synechocystis PCC6803, contain WD40 domains. Mol Microbiol. 1997 Apr; 24(1):229-30. PMID: 9140979.
      View in: PubMed
    280. Paulsen IT, Saier MH. A novel family of ubiquitous heavy metal ion transport proteins. J Membr Biol. 1997 Mar 15; 156(2):99-103. PMID: 9075641.
      View in: PubMed
    281. Crasnier-Mednansky M, Park MC, Studley WK, Saier MH. Cra-mediated regulation of Escherichia coli adenylate cyclase. Microbiology. 1997 Mar; 143 ( Pt 3):785-92. PMID: 9084162.
      View in: PubMed
    282. van Montfort RL, Pijning T, Kalk KH, Reizer J, Saier MH, Thunnissen MM, Robillard GT, Dijkstra BW. The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases. Structure. 1997 Feb 15; 5(2):217-25. PMID: 9032081.
      View in: PubMed
    283. Peekhaus N, Tong S, Reizer J, Saier MH, Murray E, Conway T. Characterization of a novel transporter family that includes multiple Escherichia coli gluconate transporters and their homologues. FEMS Microbiol Lett. 1997 Feb 15; 147(2):233-8. PMID: 9119199.
      View in: PubMed
    284. Ab E, Schuurman-Wolters G, Reizer J, Saier MH, Dijkstra K, Scheek RM, Robillard GT. The NMR side-chain assignments and solution structure of enzyme IIBcellobiose of the phosphoenolpyruvate-dependent phosphotransferase system of Escherichia coli. Protein Sci. 1997 Feb; 6(2):304-14. PMID: 9041631; PMCID: PMC2143641.
    285. Reizer J, Reizer A, Perego M, Saier MH. Characterization of a family of bacterial response regulator aspartyl-phosphate (RAP) phosphatases. Microb Comp Genomics. 1997; 2(2):103-11. PMID: 9689219.
      View in: PubMed
    286. Saier MH, Paulsen IT, Matin A. A bacterial model system for understanding multi-drug resistance. Microb Drug Resist. 1997; 3(4):289-95. PMID: 9442481.
      View in: PubMed
    287. Goffeau A, Park J, Paulsen IT, Jonniaux JL, Dinh T, Mordant P, Saier MH. Multidrug-resistant transport proteins in yeast: complete inventory and phylogenetic characterization of yeast open reading frames with the major facilitator superfamily. Yeast. 1997 Jan; 13(1):43-54. PMID: 9046086.
      View in: PubMed
    288. Reizer J, Reizer A, Merrick MJ, Plunkett G, Rose DJ, Saier MH. Novel phosphotransferase-encoding genes revealed by analysis of the Escherichia coli genome: a chimeric gene encoding an Enzyme I homologue that possesses a putative sensory transduction domain. Gene. 1996 Nov 28; 181(1-2):103-8. PMID: 8973315.
      View in: PubMed
    289. Reizer J, Mitchell WJ, Minton N, Brehm J, Reizer A, Saier MH. Proposed topology of the glucitol permeases of Escherichia coli and Clostridium acetobutylicum. Curr Microbiol. 1996 Nov; 33(5):331-3. PMID: 8875915.
      View in: PubMed
    290. Park JH, Saier MH. Phylogenetic characterization of the MIP family of transmembrane channel proteins. J Membr Biol. 1996 Oct; 153(3):171-80. PMID: 8849412.
      View in: PubMed
    291. Hoischen C, Levin J, Pitaknarongphorn S, Reizer J, Saier MH. Involvement of the central loop of the lactose permease of Escherichia coli in its allosteric regulation by the glucose-specific enzyme IIA of the phosphoenolpyruvate-dependent phosphotransferase system. J Bacteriol. 1996 Oct; 178(20):6082-6. PMID: 8830713; PMCID: PMC178473.
    292. Ramseier TM, Chien SY, Saier MH. Cooperative interaction between Cra and Fnr in the regulation of the cydAB operon of Escherichia coli. Curr Microbiol. 1996 Oct; 33(4):270-4. PMID: 8824175.
      View in: PubMed
    293. Naderi S, Saier MH. Plant sucrose:H+ symporters are homologous to the melibiose permease of Escherichia coli. Mol Microbiol. 1996 Oct; 22(2):390-1. PMID: 8930923.
      View in: PubMed
    294. Reizer J, Bergstedt U, Galinier A, Küster E, Saier MH, Hillen W, Steinmetz M, Deutscher J. Catabolite repression resistance of gnt operon expression in Bacillus subtilis conferred by mutation of His-15, the site of phosphoenolpyruvate-dependent phosphorylation of the phosphocarrier protein HPr. J Bacteriol. 1996 Sep; 178(18):5480-6. PMID: 8808939; PMCID: PMC178371.
    295. Macfadyen LP, Dorocicz IR, Reizer J, Saier MH, Redfield RJ. Regulation of competence development and sugar utilization in Haemophilus influenzae Rd by a phosphoenolpyruvate:fructose phosphotransferase system. Mol Microbiol. 1996 Sep; 21(5):941-52. PMID: 8885265.
      View in: PubMed
    296. Arnaud M, Débarbouillé M, Rapoport G, Saier MH, Reizer J. In vitro reconstitution of transcriptional antitermination by the SacT and SacY proteins of Bacillus subtilis. J Biol Chem. 1996 Aug 02; 271(31):18966-72. PMID: 8702561.
      View in: PubMed
    297. Saier MH. Regulatory interactions controlling carbon metabolism: an overview. Res Microbiol. 1996 Jul-Sep; 147(6-7):439-47. PMID: 9084753.
      View in: PubMed
    298. Le T, Saier MH. Phylogenetic characterization of the epithelial Na+ channel (ENaC) family. Mol Membr Biol. 1996 Jul-Sep; 13(3):149-57. PMID: 8905643.
      View in: PubMed
    299. Saier MH, Crasnier M. Inducer exclusion and the regulation of sugar transport. Res Microbiol. 1996 Jul-Sep; 147(6-7):482-9. PMID: 9084759.
      View in: PubMed
    300. Nguyen CC, Saier MH. Structural and phylogenetic analysis of the MotA and MotB families of bacterial flagellar motor proteins. Res Microbiol. 1996 Jun; 147(5):317-32. PMID: 8763618.
      View in: PubMed
    301. Saier MH, Ramseier TM. The catabolite repressor/activator (Cra) protein of enteric bacteria. J Bacteriol. 1996 Jun; 178(12):3411-7. PMID: 8655535; PMCID: PMC178107.
    302. Ye JJ, Saier MH. Regulation of sugar uptake via the phosphoenolpyruvate-dependent phosphotransferase systems in Bacillus subtilis and Lactococcus lactis is mediated by ATP-dependent phosphorylation of seryl residue 46 in HPr. J Bacteriol. 1996 Jun; 178(12):3557-63. PMID: 8655554; PMCID: PMC178126.
    303. Reizer J, Reizer A, Saier MH. Novel PTS proteins revealed by bacterial genome sequencing: a unique fructose-specific phosphoryl transfer protein with two HPr-like domains in Haemophilus influenzae. Res Microbiol. 1996 May; 147(4):209-15. PMID: 8763608.
      View in: PubMed
    304. Saier MH. Cyclic AMP-independent catabolite repression in bacteria. FEMS Microbiol Lett. 1996 May 01; 138(2-3):97-103. PMID: 9026456.
      View in: PubMed
    305. Charbit A, Reizer J, Saier MH. Function of the duplicated IIB domain and oligomeric structure of the fructose permease of Escherichia coli. J Biol Chem. 1996 Apr 26; 271(17):9997-10003. PMID: 8626640.
      View in: PubMed
    306. Ye JJ, Minarcik J, Saier MH. Inducer expulsion and the occurrence of an HPr(Ser-P)-activated sugar-phosphate phosphatase in Enterococcus faecalis and Streptococcus pyogenes. Microbiology. 1996 Mar; 142 ( Pt 3):585-92. PMID: 8868433.
      View in: PubMed
    307. Du Y, Holtel A, Reizer J, Saier MH. sigma54-dependent transcription of the Pseudomonas putida xylS operon is influenced by the IIANtr protein of the phosphotransferase system in Escherichia coli. Res Microbiol. 1996 Mar-Apr; 147(3):129-32. PMID: 8761731.
      View in: PubMed
    308. Paulsen IT, Skurray RA, Tam R, Saier MH, Turner RJ, Weiner JH, Goldberg EB, Grinius LL. The SMR family: a novel family of multidrug efflux proteins involved with the efflux of lipophilic drugs. Mol Microbiol. 1996 Mar; 19(6):1167-75. PMID: 8730859.
      View in: PubMed
    309. Park JH, Saier MH. Phylogenetic, structural and functional characteristics of the Na-K-Cl cotransporter family. J Membr Biol. 1996 Feb; 149(3):161-8. PMID: 8801348.
      View in: PubMed
    310. Reizer J, Ramseier TM, Reizer A, Charbit A, Saier MH. Novel phosphotransferase genes revealed by bacterial genome sequencing: a gene cluster encoding a putative N-acetylgalactosamine metabolic pathway in Escherichia coli. Microbiology. 1996 Feb; 142 ( Pt 2):231-50. PMID: 8932697.
      View in: PubMed
    311. Saier MH, Chauvaux S, Cook GM, Deutscher J, Paulsen IT, Reizer J, Ye JJ. Catabolite repression and inducer control in Gram-positive bacteria. Microbiology. 1996 Feb; 142 ( Pt 2):217-30. PMID: 8932696.
      View in: PubMed
    312. Koch S, Sutrina SL, Wu LF, Reizer J, Schnetz K, Rak B, Saier MH. Identification of a site in the phosphocarrier protein, HPr, which influences its interactions with sugar permeases of the bacterial phosphotransferase system: kinetic analyses employing site-specific mutants. J Bacteriol. 1996 Feb; 178(4):1126-33. PMID: 8576048; PMCID: PMC177775.
    313. Bledig SA, Ramseier TM, Saier MH. Frur mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli. J Bacteriol. 1996 Jan; 178(1):280-3. PMID: 8550429; PMCID: PMC177650.
    314. Saier MH. Phylogenetic approaches to the identification and characterization of protein families and superfamilies. Microb Comp Genomics. 1996; 1(3):129-50. PMID: 9689209.
      View in: PubMed
    315. Saier MH, Ye JJ, Klinke S, Nino E. Identification of an anaerobically induced phosphoenolpyruvate-dependent fructose-specific phosphotransferase system and evidence for the Embden-Meyerhof glycolytic pathway in the heterofermentative bacterium Lactobacillus brevis. J Bacteriol. 1996 Jan; 178(1):314-6. PMID: 8550437; PMCID: PMC177658.
    316. Reizer J, Paulsen IT, Reizer A, Titgemeyer F, Saier MH. Novel phosphotransferase system genes revealed by bacterial genome analysis: the complete complement of pts genes in mycoplasma genitalium. Microb Comp Genomics. 1996; 1(3):151-64. PMID: 9689210.
      View in: PubMed
    317. Blair A, Ngo L, Park J, Paulsen IT, Saier MH. Phylogenetic analyses of the homologous transmembrane channel-forming proteins of the F0F1-ATPases of bacteria, chloroplasts and mitochondria. Microbiology. 1996 Jan; 142 ( Pt 1):17-32. PMID: 8581162.
      View in: PubMed
    318. Tsang S, Saier MH. A simple flexible program for the computational analysis of amino acyl residue distribution in proteins: application to the distribution of aromatic versus aliphatic hydrophobic amino acids in transmembrane alpha-helical spanners of integral membrane transport proteins. J Comput Biol. 1996; 3(1):185-90. PMID: 8697235.
      View in: PubMed
    319. Nguyen CC, Saier MH. Phylogenetic, structural and functional analyses of the LacI-GalR family of bacterial transcription factors. FEBS Lett. 1995 Dec 18; 377(2):98-102. PMID: 8543068.
      View in: PubMed
    320. Cook GM, Ye JJ, Russell JB, Saier MH. Properties of two sugar phosphate phosphatases from Streptococcus bovis and their potential involvement in inducer expulsion. J Bacteriol. 1995 Dec; 177(23):7007-9. PMID: 7592500; PMCID: PMC177575.
    321. Pullen K, Rajagopal P, Branchini BR, Huffine ME, Reizer J, Saier MH, Scholtz JM, Klevit RE. Phosphorylation of serine-46 in HPr, a key regulatory protein in bacteria, results in stabilization of its solution structure. Protein Sci. 1995 Dec; 4(12):2478-86. PMID: 8580838; PMCID: PMC2143046.
    322. Nguyen CC, Saier MH. Phylogenetic analysis of the putative phosphorylation domain in the pyruvate kinase of Bacillus stearothermophilus. Res Microbiol. 1995 Nov-Dec; 146(9):713-9. PMID: 8584793.
      View in: PubMed
    323. Dagnall BH, Paulsen IT, Saier MH. The DAG family of glycosyl hydrolases combines two previously identified protein families. Biochem J. 1995 Oct 01; 311 ( Pt 1):349-50. PMID: 7575475; PMCID: PMC1136158.
    324. Vartak NB, Lin CC, Cleary JM, Fagan MJ, Saier MH. Glucose metabolism in 'Sphingomonas elodea': pathway engineering via construction of a glucose-6-phosphate dehydrogenase insertion mutant. Microbiology. 1995 Sep; 141 ( Pt 9):2339-50. PMID: 7496544.
      View in: PubMed
    325. Cook GM, Kearns DB, Russell JB, Reizer J, Saier MH. Regulation of the lactose phosphotransferase system of Streptococcus bovis by glucose: independence of inducer exclusion and expulsion mechanisms. Microbiology. 1995 Sep; 141 ( Pt 9):2261-9. PMID: 7496538.
      View in: PubMed
    326. Ramseier TM, Saier MH. cAMP-cAMP receptor protein complex: five binding sites in the control region of the Escherichia coli mannitol operon. Microbiology. 1995 Aug; 141 ( Pt 8):1901-7. PMID: 7551052.
      View in: PubMed
    327. Ye JJ, Saier MH. Purification and characterization of a small membrane-associated sugar phosphate phosphatase that is allosterically activated by HPr(Ser(P)) of the phosphotransferase system in Lactococcus lactis. J Biol Chem. 1995 Jul 14; 270(28):16740-4. PMID: 7622485.
      View in: PubMed
    328. Saier MH, Chauvaux S, Deutscher J, Reizer J, Ye JJ. Protein phosphorylation and regulation of carbon metabolism in gram-negative versus gram-positive bacteria. Trends Biochem Sci. 1995 Jul; 20(7):267-71. PMID: 7667879.
      View in: PubMed
    329. Ramseier TM, Reizer J, Küster E, Hillen W, Saier MH. In vitro binding of the CcpA protein of Bacillus megaterium to cis-acting catabolite responsive elements (CREs) of gram-positive bacteria. FEMS Microbiol Lett. 1995 Jun 15; 129(2-3):207-13. PMID: 7607401.
      View in: PubMed
    330. Ramseier TM, Bledig S, Michotey V, Feghali R, Saier MH. The global regulatory protein FruR modulates the direction of carbon flow in Escherichia coli. Mol Microbiol. 1995 Jun; 16(6):1157-69. PMID: 8577250.
      View in: PubMed
    331. Ramseier TM, Inui M, Saier MH. CarRS of Azospirillum brasilense is homologous to a large family of aldehyde dehydrogenases rather than to two-component regulators. Res Microbiol. 1995 Jun; 146(5):425-9. PMID: 8525059.
      View in: PubMed
    332. Tsai MH, Saier MH. Phylogenetic characterization of the ubiquitous electron transfer flavoprotein families ETF-alpha and ETF-beta. Res Microbiol. 1995 Jun; 146(5):397-404. PMID: 8525056.
      View in: PubMed
    333. Kuan G, Dassa E, Saurin W, Hofnung M, Saier MH. Phylogenetic analyses of the ATP-binding constituents of bacterial extracytoplasmic receptor-dependent ABC-type nutrient uptake permeases. Res Microbiol. 1995 May; 146(4):271-8. PMID: 7569321.
      View in: PubMed
    334. Espanol MJ, Saier MH. Topological and segmental phylogenetic analyses of the anion exchanger (band 3) family of transporters. Mol Membr Biol. 1995 Apr-Jun; 12(2):193-200. PMID: 7795710.
      View in: PubMed
    335. Reizer J, Reizer A, Saier MH. Novel phosphotransferase system genes revealed by bacterial genome analysis--a gene cluster encoding a unique Enzyme I and the proteins of a fructose-like permease system. Microbiology. 1995 Apr; 141 ( Pt 4):961-71. PMID: 7773398.
      View in: PubMed
    336. Ye JJ, Saier MH. Allosteric regulation of the glucose:H+ symporter of Lactobacillus brevis: cooperative binding of glucose and HPr(ser-P). J Bacteriol. 1995 Apr; 177(7):1900-2. PMID: 7896720; PMCID: PMC176825.
    337. Saier MH. Differential codon usage: a safeguard against inappropriate expression of specialized genes? FEBS Lett. 1995 Mar 27; 362(1):1-4. PMID: 7535249.
      View in: PubMed
    338. Powell BS, Court DL, Inada T, Nakamura Y, Michotey V, Cui X, Reizer A, Saier MH, Reizer J. Novel proteins of the phosphotransferase system encoded within the rpoN operon of Escherichia coli. Enzyme IIANtr affects growth on organic nitrogen and the conditional lethality of an erats mutant. J Biol Chem. 1995 Mar 03; 270(9):4822-39. PMID: 7876255.
      View in: PubMed
    339. Ryu S, Ramseier TM, Michotey V, Saier MH, Garges S. Effect of the FruR regulator on transcription of the pts operon in Escherichia coli. J Biol Chem. 1995 Feb 10; 270(6):2489-96. PMID: 7852310.
      View in: PubMed
    340. Pao GM, Saier MH. Response regulators of bacterial signal transduction systems: selective domain shuffling during evolution. J Mol Evol. 1995 Feb; 40(2):136-54. PMID: 7699720.
      View in: PubMed
    341. Reizer J, Reizer A, Saier MH. Sorbose-1-P reductase (SorE) and the glucitol-6-P dehydrogenase (SorD) of the Klebsiella pneumoniae L-sorbose operon belong to the zinc-dependent dehydrogenase family and the short chain alcohol dehydrogenase family, respectively. Res Microbiol. 1995 Feb; 146(2):183-4. PMID: 7652212.
      View in: PubMed
    342. Ye JJ, Saier MH. Cooperative binding of lactose and the phosphorylated phosphocarrier protein HPr(Ser-P) to the lactose/H+ symport permease of Lactobacillus brevis. Proc Natl Acad Sci U S A. 1995 Jan 17; 92(2):417-21. PMID: 7831302; PMCID: PMC42751.
    343. Titgemeyer F, Walkenhorst J, Reizer J, Stuiver MH, Cui X, Saier MH. Identification and characterization of phosphoenolpyruvate:fructose phosphotransferase systems in three Streptomyces species. Microbiology. 1995 Jan; 141 ( Pt 1):51-8. PMID: 7894719.
      View in: PubMed
    344. Titgemeyer F, Reizer J, Reizer A, Tang J, Parr TR, Saier MH. Nucleotide sequence of the region between crr and cysM in Salmonella typhimurium: five novel ORFs including one encoding a putative transcriptional regulator of the phosphotransferase system. DNA Seq. 1995; 5(3):145-52. PMID: 7612925.
      View in: PubMed
    345. Ye JJ, Reizer J, Saier MH. Regulation of 2-deoxyglucose phosphate accumulation in Lactococcus lactis vesicles by metabolite-activated, ATP-dependent phosphorylation of serine-46 in HPr of the phosphotransferase system. Microbiology. 1994 Dec; 140 ( Pt 12):3421-9. PMID: 7881559.
      View in: PubMed
    346. Pao GM, Saier MH. The N-terminal, putative, mitochondrial targeting domain of the mitochondrial genome maintenance protein (MGM1) in yeast is homologous to the bacterial ribonuclease inhibitor, barstar. Mol Biol Evol. 1994 Nov; 11(6):964-5. PMID: 7815934.
      View in: PubMed
    347. Saier MH. Bacterial protein kinases that recognize tertiary rather than primary structure? Res Microbiol. 1994 Nov-Dec; 145(9):647-50. PMID: 7746953.
      View in: PubMed
    348. Saier MH, Reizer J. The bacterial phosphotransferase system: new frontiers 30 years later. Mol Microbiol. 1994 Sep; 13(5):755-64. PMID: 7815935.
      View in: PubMed
    349. Titgemeyer F, Reizer J, Reizer A, Saier MH. Evolutionary relationships between sugar kinases and transcriptional repressors in bacteria. Microbiology. 1994 Sep; 140 ( Pt 9):2349-54. PMID: 7952186.
      View in: PubMed
    350. Hueck CJ, Hillen W, Saier MH. Analysis of a cis-active sequence mediating catabolite repression in gram-positive bacteria. Res Microbiol. 1994 Sep; 145(7):503-18. PMID: 7855437.
      View in: PubMed
    351. Isaacs H, Chao D, Yanofsky C, Saier MH. Mechanism of catabolite repression of tryptophanase synthesis in Escherichia coli. Microbiology. 1994 Aug; 140 ( Pt 8):2125-34. PMID: 7921262.
      View in: PubMed
    352. Dinh T, Paulsen IT, Saier MH. A family of extracytoplasmic proteins that allow transport of large molecules across the outer membranes of gram-negative bacteria. J Bacteriol. 1994 Jul; 176(13):3825-31. PMID: 8021163; PMCID: PMC205578.
    353. Reizer J, Reizer A, Saier MH. A functional superfamily of sodium/solute symporters. Biochim Biophys Acta. 1994 Jun 29; 1197(2):133-66. PMID: 8031825.
      View in: PubMed
    354. van Montfort RL, Pijning T, Kalk KH, Schuurman-Wolters GK, Reizer J, Saier MH, Robillard G, Dijkstra BW. Crystallization of enzyme IIB of the cellobiose-specific phosphotransferase system of Escherichia coli. J Mol Biol. 1994 Jun 17; 239(4):588-90. PMID: 8006971.
      View in: PubMed
    355. Ye JJ, Neal JW, Cui X, Reizer J, Saier MH. Regulation of the glucose:H+ symporter by metabolite-activated ATP-dependent phosphorylation of HPr in Lactobacillus brevis. J Bacteriol. 1994 Jun; 176(12):3484-92. PMID: 8206825; PMCID: PMC205535.
    356. Deutscher J, Reizer J, Fischer C, Galinier A, Saier MH, Steinmetz M. Loss of protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system, by mutation of the ptsH gene confers catabolite repression resistance to several catabolic genes of Bacillus subtilis. J Bacteriol. 1994 Jun; 176(11):3336-44. PMID: 8195089; PMCID: PMC205505.
    357. Saier MH. Bacterial sensor kinase/response regulator systems: an introduction. Res Microbiol. 1994 Jun-Aug; 145(5-6):349-55. PMID: 7855419.
      View in: PubMed
    358. Pao GM, Tam R, Lipschitz LS, Saier MH. Response regulators: structure, function and evolution. Res Microbiol. 1994 Jun-Aug; 145(5-6):356-62. PMID: 7855420.
      View in: PubMed
    359. Cortay JC, Nègre D, Scarabel M, Ramseier TM, Vartak NB, Reizer J, Saier MH, Cozzone AJ. In vitro asymmetric binding of the pleiotropic regulatory protein, FruR, to the ace operator controlling glyoxylate shunt enzyme synthesis. J Biol Chem. 1994 May 27; 269(21):14885-91. PMID: 8195118.
      View in: PubMed
    360. Reizer J, Reizer A, Kornberg HL, Saier MH. Sequence of the fruB gene of Escherichia coli encoding the diphosphoryl transfer protein (DTP) of the phosphoenolpyruvate: sugar phosphotransferase system. FEMS Microbiol Lett. 1994 May 01; 118(1-2):159-62. PMID: 8013873.
      View in: PubMed
    361. Reizer J, Buskirk S, Bairoch A, Reizer A, Saier MH. A novel zinc-binding motif found in two ubiquitous deaminase families. Protein Sci. 1994 May; 3(5):853-6. PMID: 8061614; PMCID: PMC2142716.
    362. Kuan G, Saier MH. Phylogenetic relationships among bacteriorhodopsins. Res Microbiol. 1994 May; 145(4):273-85. PMID: 7997641.
      View in: PubMed
    363. Ye JJ, Reizer J, Cui X, Saier MH. Inhibition of the phosphoenolpyruvate:lactose phosphotransferase system and activation of a cytoplasmic sugar-phosphate phosphatase in Lactococcus lactis by ATP-dependent metabolite-activated phosphorylation of serine 46 in the phosphocarrier protein HPr. J Biol Chem. 1994 Apr 22; 269(16):11837-44. PMID: 8163482.
      View in: PubMed
    364. Maurel C, Reizer J, Schroeder JI, Chrispeels MJ, Saier MH. Functional characterization of the Escherichia coli glycerol facilitator, GlpF, in Xenopus oocytes. J Biol Chem. 1994 Apr 22; 269(16):11869-72. PMID: 7512955.
      View in: PubMed
    365. Ye JJ, Reizer J, Cui X, Saier MH. ATP-dependent phosphorylation of serine-46 in the phosphocarrier protein HPr regulates lactose/H+ symport in Lactobacillus brevis. Proc Natl Acad Sci U S A. 1994 Apr 12; 91(8):3102-6. PMID: 8159711; PMCID: PMC43523.
    366. Reizer J, Michotey V, Reizer A, Saier MH. Novel phosphotransferase system genes revealed by bacterial genome analysis: unique, putative fructose- and glucoside-specific systems. Protein Sci. 1994 Mar; 3(3):440-50. PMID: 8019415; PMCID: PMC2142697.
    367. Saier MH, Tam R, Reizer A, Reizer J. Two novel families of bacterial membrane proteins concerned with nodulation, cell division and transport. Mol Microbiol. 1994 Mar; 11(5):841-7. PMID: 8022262.
      View in: PubMed
    368. Saier MH. Computer-aided analyses of transport protein sequences: gleaning evidence concerning function, structure, biogenesis, and evolution. Microbiol Rev. 1994 Mar; 58(1):71-93. PMID: 8177172; PMCID: PMC372954.
    369. Figge RM, Ramseier TM, Saier MH. The mannitol repressor (MtlR) of Escherichia coli. J Bacteriol. 1994 Feb; 176(3):840-7. PMID: 8300537; PMCID: PMC205122.
    370. Ab E, Schuurman-Wolters GK, Saier MH, Reizer J, Jacuinod M, Roepstorff P, Dijkstra K, Scheek RM, Robillard GT. Enzyme IIBcellobiose of the phosphoenol-pyruvate-dependent phosphotransferase system of Escherichia coli: backbone assignment and secondary structure determined by three-dimensional NMR spectroscopy. Protein Sci. 1994 Feb; 3(2):282-90. PMID: 8003964; PMCID: PMC2142798.
    371. Titgemeyer F, Walkenhorst J, Cui X, Reizer J, Saier MH. Proteins of the phosphoenolpyruvate:sugar phosphotransferase system in Streptomyces: possible involvement in the regulation of antibiotic production. Res Microbiol. 1994 Feb; 145(2):89-92. PMID: 8090996.
      View in: PubMed
    372. Saier MH. Protein uptake into E. coli during Bdellovibrio infection. A process of reverse secretion? FEBS Lett. 1994 Jan 03; 337(1):14-7. PMID: 8276104.
      View in: PubMed
    373. Titgemeyer F, Mason RE, Saier MH. Regulation of the raffinose permease of Escherichia coli by the glucose-specific enzyme IIA of the phosphoenolpyruvate:sugar phosphotransferase system. J Bacteriol. 1994 Jan; 176(2):543-6. PMID: 8288553; PMCID: PMC205084.
    374. Reizer A, Saier MH, Reizer J. Classification and function prediction of proteins using diagnostic amino acid patterns. Methods Mol Biol. 1994; 25:295-305. PMID: 8004172.
      View in: PubMed
    375. Fagan MJ, Saier MH. P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees. J Mol Evol. 1994 Jan; 38(1):57-99. PMID: 8151716.
      View in: PubMed
    376. Ramseier TM, Figge RM, Saier MH. DNA sequence of a gene in Escherichia coli encoding a putative tripartite transcription factor with receiver, ATPase and DNA binding domains. DNA Seq. 1994; 5(1):17-24. PMID: 7894055.
      View in: PubMed
    377. Saier MH. Convergence and divergence in the evolution of transport proteins. Bioessays. 1994 Jan; 16(1):23-9. PMID: 7511376.
      View in: PubMed
    378. Ramseier TM, Nègre D, Cortay JC, Scarabel M, Cozzone AJ, Saier MH. In vitro binding of the pleiotropic transcriptional regulatory protein, FruR, to the fru, pps, ace, pts and icd operons of Escherichia coli and Salmonella typhimurium. J Mol Biol. 1993 Nov 05; 234(1):28-44. PMID: 8230205.
      View in: PubMed
    379. Hoischen C, Dijkstra A, Rottem S, Reizer J, Saier MH. Presence of protein constituents of the gram-positive bacterial phosphotransferase regulatory system in Acholeplasma laidlawii. J Bacteriol. 1993 Oct; 175(20):6599-604. PMID: 8407837; PMCID: PMC206771.
    380. Van Rosmalen M, Saier MH. Structural and evolutionary relationships between two families of bacterial extracytoplasmic chaperone proteins which function cooperatively in fimbrial assembly. Res Microbiol. 1993 Sep; 144(7):507-27. PMID: 7906046.
      View in: PubMed
    381. Reizer J, Reizer A, Saier MH, Bork P, Sander C. Exopolyphosphate phosphatase and guanosine pentaphosphate phosphatase belong to the sugar kinase/actin/hsp 70 superfamily. Trends Biochem Sci. 1993 Jul; 18(7):247-8. PMID: 8212131.
      View in: PubMed
    382. Tam R, Saier MH. Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Microbiol Rev. 1993 Jun; 57(2):320-46. PMID: 8336670; PMCID: PMC372912.
    383. Reizer J, Reizer A, Bairoch A, Saier MH. A diverse transketolase family that includes the RecP protein of Streptococcus pneumoniae, a protein implicated in genetic recombination. Res Microbiol. 1993 Jun; 144(5):341-7. PMID: 8248627.
      View in: PubMed
    384. Mitchell WJ, Reizer J, Herring C, Hoischen C, Saier MH. Identification of a phosphoenolpyruvate:fructose phosphotransferase system (fructose-1-phosphate forming) in Listeria monocytogenes. J Bacteriol. 1993 May; 175(9):2758-61. PMID: 8478337; PMCID: PMC204581.
    385. Reizer J, Hoischen C, Reizer A, Pham TN, Saier MH. Sequence analyses and evolutionary relationships among the energy-coupling proteins Enzyme I and HPr of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. Protein Sci. 1993 Apr; 2(4):506-21. PMID: 7686067; PMCID: PMC2142364.
    386. Tam R, Saier MH. A bacterial periplasmic receptor homologue with catalytic activity: cyclohexadienyl dehydratase of Pseudomonas aeruginosa is homologous to receptors specific for polar amino acids. Res Microbiol. 1993 Mar-Apr; 144(3):165-9. PMID: 8210673.
      View in: PubMed
    387. Chen Y, Reizer J, Saier MH, Fairbrother WJ, Wright PE. Mapping of the binding interfaces of the proteins of the bacterial phosphotransferase system, HPr and IIAglc. Biochemistry. 1993 Jan 12; 32(1):32-7. PMID: 8418852.
      View in: PubMed
    388. Saier MH. Introduction: protein phosphorylation and signal transduction in bacteria. J Cell Biochem. 1993 Jan; 51(1):1-6. PMID: 8381788.
      View in: PubMed
    389. Reizer J, Reizer A, Saier MH. The MIP family of integral membrane channel proteins: sequence comparisons, evolutionary relationships, reconstructed pathway of evolution, and proposed functional differentiation of the two repeated halves of the proteins. Crit Rev Biochem Mol Biol. 1993; 28(3):235-57. PMID: 8325040.
      View in: PubMed
    390. Yamada M, Asaoka S, Saier MH, Yamada Y. Characterization of the gcd gene from Escherichia coli K-12 W3110 and regulation of its expression. J Bacteriol. 1993 Jan; 175(2):568-71. PMID: 8419307; PMCID: PMC196176.
    391. Saier MH. Regulatory interactions involving the proteins of the phosphotransferase system in enteric bacteria. J Cell Biochem. 1993 Jan; 51(1):62-8. PMID: 8432744.
      View in: PubMed
    392. Marger MD, Saier MH. A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport. Trends Biochem Sci. 1993 Jan; 18(1):13-20. PMID: 8438231.
      View in: PubMed
    393. Kuan J, Saier MH. The mitochondrial carrier family of transport proteins: structural, functional, and evolutionary relationships. Crit Rev Biochem Mol Biol. 1993; 28(3):209-33. PMID: 8325039.
      View in: PubMed
    394. Reizer J, Finley K, Kakuda D, MacLeod CL, Reizer A, Saier MH. Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria. Protein Sci. 1993 Jan; 2(1):20-30. PMID: 8382989; PMCID: PMC2142299.
    395. Werner PK, Saier MH, Müller M. Membrane insertion of the mannitol permease of Escherichia coli occurs under conditions of impaired SecA function. J Biol Chem. 1992 Dec 05; 267(34):24523-32. PMID: 1447197.
      View in: PubMed
    396. Trandinh CC, Pao GM, Saier MH. Structural and evolutionary relationships among the immunophilins: two ubiquitous families of peptidyl-prolyl cis-trans isomerases. FASEB J. 1992 Dec; 6(15):3410-20. PMID: 1464374.
      View in: PubMed
    397. Nikaido H, Saier MH. Transport proteins in bacteria: common themes in their design. Science. 1992 Nov 06; 258(5084):936-42. PMID: 1279804.
      View in: PubMed
    398. Reizer J, Reizer A, Saier MH. A new subfamily of bacterial ABC-type transport systems catalyzing export of drugs and carbohydrates. Protein Sci. 1992 Oct; 1(10):1326-32. PMID: 1303751; PMCID: PMC2142109.
    399. Wittekind M, Rajagopal P, Branchini BR, Reizer J, Saier MH, Klevit RE. Solution structure of the phosphocarrier protein HPr from Bacillus subtilis by two-dimensional NMR spectroscopy. Protein Sci. 1992 Oct; 1(10):1363-76. PMID: 1303754; PMCID: PMC2142093.
    400. Reizer J, Reizer A, Saier MH. The putative Na+/H+ antiporter (NapA) of Enterococcus hirae is homologous to the putative K+/H+ antiporter (KefC) of Escherichia coli. FEMS Microbiol Lett. 1992 Jul 01; 73(1-2):161-3. PMID: 1325937.
      View in: PubMed
    401. Parr TR, Saier MH. The bacterial phosphotransferase system as a potential vehicle for the entry of novel antibiotics. Res Microbiol. 1992 Jun; 143(5):443-7. PMID: 1448620.
      View in: PubMed
    402. Reizer J, Reizer A, Saier MH, Jacobson GR. A proposed link between nitrogen and carbon metabolism involving protein phosphorylation in bacteria. Protein Sci. 1992 Jun; 1(6):722-6. PMID: 1304914; PMCID: PMC2142240.
    403. Stone MJ, Fairbrother WJ, Palmer AG, Reizer J, Saier MH, Wright PE. Backbone dynamics of the Bacillus subtilis glucose permease IIA domain determined from 15N NMR relaxation measurements. Biochemistry. 1992 May 12; 31(18):4394-406. PMID: 1316146.
      View in: PubMed
    404. Fairbrother WJ, Palmer AG, Rance M, Reizer J, Saier MH, Wright PE. Assignment of the aliphatic 1H and 13C resonances of the Bacillus subtilis glucose permease IIA domain using double- and triple-resonance heteronuclear three-dimensional NMR spectroscopy. Biochemistry. 1992 May 12; 31(18):4413-25. PMID: 1581296.
      View in: PubMed
    405. Reizer J, Sutrina SL, Wu LF, Deutscher J, Reddy P, Saier MH. Functional interactions between proteins of the phosphoenolpyruvate:sugar phosphotransferase systems of Bacillus subtilis and Escherichia coli. J Biol Chem. 1992 May 05; 267(13):9158-69. PMID: 1577753.
      View in: PubMed
    406. Groisman EA, Saier MH, Ochman H. Horizontal transfer of a phosphatase gene as evidence for mosaic structure of the Salmonella genome. EMBO J. 1992 Apr; 11(4):1309-16. PMID: 1339343; PMCID: PMC556579.
    407. Herzberg O, Reddy P, Sutrina S, Saier MH, Reizer J, Kapadia G. Structure of the histidine-containing phosphocarrier protein HPr from Bacillus subtilis at 2.0-A resolution. Proc Natl Acad Sci U S A. 1992 Mar 15; 89(6):2499-503. PMID: 1549615; PMCID: PMC48686.
    408. Saier MH, Reizer J. Proposed uniform nomenclature for the proteins and protein domains of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. J Bacteriol. 1992 Mar; 174(5):1433-8. PMID: 1537788; PMCID: PMC206537.
    409. Anderson JW, Waygood EB, Saier MH, Reizer J. Properties of phosphorylated protein intermediates of the bacterial phosphoenolpyruvate:sugar phosphotransferase system. Biochem Cell Biol. 1992 Mar-Apr; 70(3-4):242-6. PMID: 1515124.
      View in: PubMed
    410. Reizer J, Saier MH, Reizer A. Possible problems with the protein sequence comparison program FASTA. Trends Biochem Sci. 1992 Feb; 17(2):60. PMID: 1566329.
      View in: PubMed
    411. Fairbrother WJ, Gippert GP, Reizer J, Saier MH, Wright PE. Low resolution solution structure of the Bacillus subtilis glucose permease IIA domain derived from heteronuclear three-dimensional NMR spectroscopy. FEBS Lett. 1992 Jan 20; 296(2):148-52. PMID: 1733770.
      View in: PubMed
    412. Romo AJ, Ruby EG, Saier MH. Effect of Bdellovibrio bacteriovorus infection on the phosphoenolpyruvate:sugar phosphotransferase system in Escherichia coli: evidence for activation of cytoplasmic proteolysis. Res Microbiol. 1992 Jan; 143(1):5-14. PMID: 1322553.
      View in: PubMed
    413. Celikel R, Dai XP, Stewart GC, Sutrina SL, Saier MH, Xuong NH, Reizer J. Crystallization and preliminary X-ray analysis of the lactose-specific phosphocarrier protein IIAlac of the phosphoenolpyruvate: sugar phosphotransferase system from Staphylococcus aureus. J Mol Biol. 1991 Dec 20; 222(4):857-9. PMID: 1762152.
      View in: PubMed
    414. Saier MH. A multiplicity of potential carbon catabolite repression mechanisms in prokaryotic and eukaryotic microorganisms. New Biol. 1991 Dec; 3(12):1137-47. PMID: 1667478.
      View in: PubMed
    415. Vartak NB, Reizer J, Reizer A, Gripp JT, Groisman EA, Wu LF, Tomich JM, Saier MH. Sequence and evolution of the FruR protein of Salmonella typhimurium: a pleiotropic transcriptional regulatory protein possessing both activator and repressor functions which is homologous to the periplasmic ribose-binding protein. Res Microbiol. 1991 Nov-Dec; 142(9):951-63. PMID: 1805309.
      View in: PubMed
    416. Wu LF, Saier MH. Differences in codon usage among genes encoding proteins of different function in Rhodobacter capsulatus. Res Microbiol. 1991 Nov-Dec; 142(9):943-9. PMID: 1805308.
      View in: PubMed
    417. Kapadia G, Chen CC, Reddy P, Saier MH, Reizer J, Herzberg O. Crystallization of the IIA domain of the glucose permease of Bacillus subtilis. J Mol Biol. 1991 Oct 20; 221(4):1079-80. PMID: 1942043.
      View in: PubMed
    418. Liao DI, Kapadia G, Reddy P, Saier MH, Reizer J, Herzberg O. Structure of the IIA domain of the glucose permease of Bacillus subtilis at 2.2-A resolution. Biochemistry. 1991 Oct 08; 30(40):9583-94. PMID: 1911744.
      View in: PubMed
    419. Yamada Y, Chang YY, Daniels GA, Wu LF, Tomich JM, Yamada M, Saier MH. Insertion of the mannitol permease into the membrane of Escherichia coli. Possible involvement of an N-terminal amphiphilic sequence. J Biol Chem. 1991 Sep 25; 266(27):17863-71. PMID: 1917927.
      View in: PubMed
    420. Reizer A, Pao GM, Saier MH. Evolutionary relationships among the permease proteins of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. Construction of phylogenetic trees and possible relatedness to proteins of eukaryotic mitochondria. J Mol Evol. 1991 Aug; 33(2):179-93. PMID: 1920454.
      View in: PubMed
    421. Fairbrother WJ, Cavanagh J, Dyson HJ, Palmer AG, Sutrina SL, Reizer J, Saier MH, Wright PE. Polypeptide backbone resonance assignments and secondary structure of Bacillus subtilis enzyme IIIglc determined by two-dimensional and three-dimensional heteronuclear NMR spectroscopy. Biochemistry. 1991 Jul 16; 30(28):6896-907. PMID: 1906345.
      View in: PubMed
    422. Reizer A, Deutscher J, Saier MH, Reizer J. Analysis of the gluconate (gnt) operon of Bacillus subtilis. Mol Microbiol. 1991 May; 5(5):1081-9. PMID: 1659648.
      View in: PubMed
    423. Wu LF, Reizer A, Reizer J, Cai B, Tomich JM, Saier MH. Nucleotide sequence of the Rhodobacter capsulatus fruK gene, which encodes fructose-1-phosphate kinase: evidence for a kinase superfamily including both phosphofructokinases of Escherichia coli. J Bacteriol. 1991 May; 173(10):3117-27. PMID: 1850730; PMCID: PMC207905.
    424. Pao GM, Wu LF, Johnson KD, Höfte H, Chrispeels MJ, Sweet G, Sandal NN, Saier MH. Evolution of the MIP family of integral membrane transport proteins. Mol Microbiol. 1991 Jan; 5(1):33-7. PMID: 2014003.
      View in: PubMed
    425. Dean DA, Reizer J, Nikaido H, Saier MH. Regulation of the maltose transport system of Escherichia coli by the glucose-specific enzyme III of the phosphoenolpyruvate-sugar phosphotransferase system. Characterization of inducer exclusion-resistant mutants and reconstitution of inducer exclusion in proteoliposomes. J Biol Chem. 1990 Dec 05; 265(34):21005-10. PMID: 2250006.
      View in: PubMed
    426. Wu LF, Saier MH. Nucleotide sequence of the fruA gene, encoding the fructose permease of the Rhodobacter capsulatus phosphotransferase system, and analyses of the deduced protein sequence. J Bacteriol. 1990 Dec; 172(12):7167-78. PMID: 2254279; PMCID: PMC210842.
    427. Romano AH, Saier MH, Harriott OT, Reizer J. Physiological studies on regulation of glycerol utilization by the phosphoenolpyruvate:sugar phosphotransferase system in Enterococcus faecalis. J Bacteriol. 1990 Dec; 172(12):6741-8. PMID: 2123855; PMCID: PMC210788.
    428. Reizer J, Reizer A, Saier MH. The cellobiose permease of Escherichia coli consists of three proteins and is homologous to the lactose permease of Staphylococcus aureus. Res Microbiol. 1990 Nov-Dec; 141(9):1061-7. PMID: 2092358.
      View in: PubMed
    429. Saier MH, Reizer J. Domain shuffling during evolution of the proteins of the bacterial phosphotransferase system. Res Microbiol. 1990 Nov-Dec; 141(9):1033-8. PMID: 2092356.
      View in: PubMed
    430. Jiang W, Wu LF, Tomich J, Saier MH, Niehaus WG. Corrected sequence of the mannitol (mtl) operon in Escherichia coli. Mol Microbiol. 1990 Nov; 4(11):2003-6. PMID: 1964486.
      View in: PubMed
    431. Reizer J, Reizer A, Saier MH. The Na+/pantothenate symporter (PanF) of Escherichia coli is homologous to the Na+/proline symporter (PutP) of E. coli and the Na+/glucose symporters of mammals. Res Microbiol. 1990 Nov-Dec; 141(9):1069-72. PMID: 1965458.
      View in: PubMed
    432. Sutrina SL, Reddy P, Saier MH, Reizer J. The glucose permease of Bacillus subtilis is a single polypeptide chain that functions to energize the sucrose permease. J Biol Chem. 1990 Oct 25; 265(30):18581-9. PMID: 2120236.
      View in: PubMed
    433. Saier MH, Wu LF, Reizer J. Regulation of bacterial physiological processes by three types of protein phosphorylating systems. Trends Biochem Sci. 1990 Oct; 15(10):391-5. PMID: 2251731.
      View in: PubMed
    434. Feldheim DA, Chin AM, Nierva CT, Feucht BU, Cao YW, Xu YF, Sutrina SL, Saier MH. Physiological consequences of the complete loss of phosphoryl-transfer proteins HPr and FPr of the phosphoenolpyruvate:sugar phosphotransferase system and analysis of fructose (fru) operon expression in Salmonella typhimurium. J Bacteriol. 1990 Sep; 172(9):5459-69. PMID: 2203752; PMCID: PMC213213.
    435. Schnetz K, Sutrina SL, Saier MH, Rak B. Identification of catalytic residues in the beta-glucoside permease of Escherichia coli by site-specific mutagenesis and demonstration of interdomain cross-reactivity between the beta-glucoside and glucose systems. J Biol Chem. 1990 Aug 15; 265(23):13464-71. PMID: 2199437.
      View in: PubMed
    436. Saier MH, Wu LF, Baker ME, Sweet G, Reizer A, Reizer J. Evolution of permease diversity and energy-coupling mechanisms with special reference to the bacterial phosphotransferase system. Biochim Biophys Acta. 1990 Jul 25; 1018(2-3):248-51. PMID: 2168212.
      View in: PubMed
    437. Wu LF, Saier MH. On the evolutionary origins of the bacterial phosphoenolpyruvate:sugar phosphotransferase system. Mol Microbiol. 1990 Jul; 4(7):1219-22. PMID: 2172696.
      View in: PubMed
    438. Wu LF, Tomich JM, Saier MH. Structure and evolution of a multidomain multiphosphoryl transfer protein. Nucleotide sequence of the fruB(HI) gene in Rhodobacter capsulatus and comparisons with homologous genes from other organisms. J Mol Biol. 1990 Jun 20; 213(4):687-703. PMID: 2193161.
      View in: PubMed
    439. Kapadia G, Reizer J, Sutrina SL, Saier MH, Reddy P, Herzberg O. Crystallization of the Bacillus subtilis histidine-containing phosphocarrier protein HPr and of some of its site-directed mutants. J Mol Biol. 1990 Mar 05; 212(1):1-2. PMID: 2108249.
      View in: PubMed
    440. Sutrina SL, Schnetz K, Rak B, Saier MH. Mechanism of sugar transport and phosphorylation via permeases of the bacterial phosphotransferase system: catalytic residues in the beta-glucoside-specific permease as defined by site-specific mutagenesis. Res Microbiol. 1990 Mar-Apr; 141(3):368-74. PMID: 2281195.
      View in: PubMed
    441. Saier MH. Evolution of permease diversity and energy-coupling mechanisms: an introduction. Res Microbiol. 1990 Mar-Apr; 141(3):281-6. PMID: 2281190.
      View in: PubMed
    442. Baker ME, Saier MH. A common ancestor for bovine lens fiber major intrinsic protein, soybean nodulin-26 protein, and E. coli glycerol facilitator. Cell. 1990 Jan 26; 60(2):185-6. PMID: 2404610.
      View in: PubMed
    443. Yamada M, Yamada Y, Saier MH. Nucleotide sequence and expression of the gutQ gene within the glucitol operon of Escherichia coli. DNA Seq. 1990; 1(2):141-5. PMID: 2134185.
      View in: PubMed
    444. Groisman EA, Saier MH. Salmonella virulence: new clues to intramacrophage survival. Trends Biochem Sci. 1990 Jan; 15(1):30-3. PMID: 2180148.
      View in: PubMed
    445. Wittekind M, Reizer J, Deutscher J, Saier MH, Klevit RE. Common structural changes accompany the functional inactivation of HPr by seryl phosphorylation or by serine to aspartate substitution. Biochemistry. 1989 Dec 26; 28(26):9908-12. PMID: 2515891.
      View in: PubMed
    446. Reizer J, Deutscher J, Saier MH. Metabolite-sensitive, ATP-dependent, protein kinase-catalyzed phosphorylation of HPr, a phosphocarrier protein of the phosphotransferase system in gram-positive bacteria. Biochimie. 1989 Sep-Oct; 71(9-10):989-96. PMID: 2557095.
      View in: PubMed
    447. Saier MH, Werner PK, Müller M. Insertion of proteins into bacterial membranes: mechanism, characteristics, and comparisons with the eucaryotic process. Microbiol Rev. 1989 Sep; 53(3):333-66. PMID: 2677637; PMCID: PMC372740.
    448. Saier MH. Involvement of the bacterial phosphotransferase system in diverse mechanisms of transcriptional regulation. Res Microbiol. 1989 Jul-Aug; 140(6):349-52. PMID: 2616889.
      View in: PubMed
    449. Reizer J, Sutrina SL, Saier MH, Stewart GC, Peterkofsky A, Reddy P. Mechanistic and physiological consequences of HPr(ser) phosphorylation on the activities of the phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: studies with site-specific mutants of HPr. EMBO J. 1989 Jul; 8(7):2111-20. PMID: 2507315; PMCID: PMC401104.
    450. Saier MH. Current studies on the bacterial phosphotransferase system in the Saier laboratory (La Jolla, California, summer, 1988). FEMS Microbiol Rev. 1989 Jun; 5(1-2):183-92. PMID: 2699248.
      View in: PubMed
    451. Chin AM, Feldheim DA, Saier MH. Altered transcriptional patterns affecting several metabolic pathways in strains of Salmonella typhimurium which overexpress the fructose regulon. J Bacteriol. 1989 May; 171(5):2424-34. PMID: 2496106; PMCID: PMC209917.
    452. Saier MH. Protein phosphorylation and allosteric control of inducer exclusion and catabolite repression by the bacterial phosphoenolpyruvate: sugar phosphotransferase system. Microbiol Rev. 1989 Mar; 53(1):109-20. PMID: 2651862; PMCID: PMC372719.
    453. Tamm LK, Tomich JM, Saier MH. Membrane incorporation and induction of secondary structure of synthetic peptides corresponding to the N-terminal signal sequences of the glucitol and mannitol permeases of Escherichia coli. J Biol Chem. 1989 Feb 15; 264(5):2587-92. PMID: 2644265.
      View in: PubMed
    454. Schnierow BJ, Yamada M, Saier MH. Partial nucleotide sequence of the pts operon in Salmonella typhimurium: comparative analyses in five bacterial genera. Mol Microbiol. 1989 Jan; 3(1):113-8. PMID: 2497295.
      View in: PubMed
    455. Saier MH, Yamada M, Suda K, Erni B, Rak B, Lengeler J, Stewart GC, Waygood EB, Rapoport G. Bacterial proteins with N-terminal leader sequences resembling mitochondrial targeting sequences of eukaryotes. Biochimie. 1988 Dec; 70(12):1743-8. PMID: 3150678.
      View in: PubMed
    456. Yamada M, Saier MH. Positive and negative regulators for glucitol (gut) operon expression in Escherichia coli. J Mol Biol. 1988 Oct 05; 203(3):569-83. PMID: 3062173.
      View in: PubMed
    457. Boerner P, Saier MH. Effects of 5-azacytidine, sodium butyrate, and phorbol esters on amino acid transport system A in a kidney epithelial cell line, MDCK: evidence for multiple mechanisms of regulation. J Cell Physiol. 1988 Oct; 137(1):117-24. PMID: 2459137.
      View in: PubMed
    458. Saier MH, Deutscher J. [Coordinate control of cell growth and transport functions in a kidney cell line]. Naturwissenschaften. 1988 Sep; 75(9):451-7. PMID: 3226436.
      View in: PubMed
    459. Saier MH, Daniels GA, Boerner P, Lin J. Neutral amino acid transport systems in animal cells: potential targets of oncogene action and regulators of cellular growth. J Membr Biol. 1988 Aug; 104(1):1-20. PMID: 3054116.
      View in: PubMed
    460. Saier MH, McCaldon P. Statistical and functional analyses of viral and cellular proteins with N-terminal amphipathic alpha-helices with large hydrophobic moments: importance to macromolecular recognition and organelle targeting. J Bacteriol. 1988 May; 170(5):2296-300. PMID: 3360744; PMCID: PMC211121.
    461. Davis T, Yamada M, Elgort M, Saier MH. Nucleotide sequence of the mannitol (mtl) operon in Escherichia coli. Mol Microbiol. 1988 May; 2(3):405-12. PMID: 3135464.
      View in: PubMed
    462. Sutrina SL, Chin AM, Esch F, Saier MH. Purification and characterization of the fructose-inducible HPr-like protein, FPr, and the fructose-specific enzyme III of the phosphoenolpyruvate: sugar phosphotransferase system of Salmonella typhimurium. J Biol Chem. 1988 Apr 15; 263(11):5061-9. PMID: 3281935.
      View in: PubMed
    463. Daniels GA, Drews G, Saier MH. Properties of a Tn5 insertion mutant defective in the structural gene (fruA) of the fructose-specific phosphotransferase system of Rhodobacter capsulatus and cloning of the fru regulon. J Bacteriol. 1988 Apr; 170(4):1698-703. PMID: 2832374; PMCID: PMC211019.
    464. Sutrina SL, Reizer J, Saier MH. Inducer expulsion in Streptococcus pyogenes: properties and mechanism of the efflux reaction. J Bacteriol. 1988 Apr; 170(4):1874-7. PMID: 3280553; PMCID: PMC211044.
    465. Saier MH, Yamada M, Erni B, Suda K, Lengeler J, Ebner R, Argos P, Rak B, Schnetz K, Lee CA. Sugar permeases of the bacterial phosphoenolpyruvate-dependent phosphotransferase system: sequence comparisons. FASEB J. 1988 Mar 01; 2(3):199-208. PMID: 2832233.
      View in: PubMed
    466. Manayan R, Tenn G, Yee HB, Desai JD, Yamada M, Saier MH. Genetic analyses of the mannitol permease of Escherichia coli: isolation and characterization of a transport-deficient mutant which retains phosphorylation activity. J Bacteriol. 1988 Mar; 170(3):1290-6. PMID: 3277953; PMCID: PMC210905.
    467. Reizer J, Saier MH, Deutscher J, Grenier F, Thompson J, Hengstenberg W. The phosphoenolpyruvate:sugar phosphotransferase system in gram-positive bacteria: properties, mechanism, and regulation. Crit Rev Microbiol. 1988; 15(4):297-338. PMID: 3060316.
      View in: PubMed
    468. Yamada M, Feucht BU, Saier MH. Regulation of gluconeogenesis by the glucitol enzyme III of the phosphotransferase system in Escherichia coli. J Bacteriol. 1987 Dec; 169(12):5416-22. PMID: 2824435; PMCID: PMC213966.
    469. Yamada M, Saier MH. Physical and genetic characterization of the glucitol operon in Escherichia coli. J Bacteriol. 1987 Jul; 169(7):2990-4. PMID: 3036766; PMCID: PMC212338.
    470. Yamada M, Saier MH. Glucitol-specific enzymes of the phosphotransferase system in Escherichia coli. Nucleotide sequence of the gut operon. J Biol Chem. 1987 Apr 25; 262(12):5455-63. PMID: 3553176.
      View in: PubMed
    471. Sutrina SL, Waygood EB, Grenier FC, Saier MH. HPr/HPr-P phosphoryl exchange reaction catalyzed by the mannitol specific enzyme II of the bacterial phosphotransferase system. J Biol Chem. 1987 Feb 25; 262(6):2636-41. PMID: 3102473.
      View in: PubMed
    472. Chin AM, Feucht BU, Saier MH. Evidence for regulation of gluconeogenesis by the fructose phosphotransferase system in Salmonella typhimurium. J Bacteriol. 1987 Feb; 169(2):897-9. PMID: 3542978; PMCID: PMC211866.
    473. Chin AM, Sutrina S, Feldheim DA, Saier MH. Genetic expression of enzyme I activity of the phosphoenolpyruvate:sugar phosphotransferase system in ptsHI deletion strains of Salmonella typhimurium. J Bacteriol. 1987 Feb; 169(2):894-6. PMID: 3542977; PMCID: PMC211865.
    474. Reizer J, Saier MH. Mechanism and regulation of phosphate transport in Streptococcus pyogenes. J Bacteriol. 1987 Jan; 169(1):297-302. PMID: 3539921; PMCID: PMC211767.
    475. Grenier FC, Waygood EB, Saier MH. The bacterial phosphotransferase system: kinetic characterization of the glucose, mannitol, glucitol, and N-acetylglucosamine systems. J Cell Biochem. 1986; 31(2):97-105. PMID: 3015992.
      View in: PubMed
    476. Grenier FC, Waygood EB, Saier MH. Bacterial phosphotransferase system: regulation of the glucose and mannose enzymes II by sulfhydryl oxidation. Biochemistry. 1985 Aug 27; 24(18):4872-6. PMID: 3907693.
      View in: PubMed
    477. Grenier FC, Reizer J, Waygood EB, Saier MH. Evidence for covalently cross-linked dimers and trimers of enzyme I of the Escherichia coli phosphotransferase system. J Bacteriol. 1985 Jul; 163(1):243-7. PMID: 3891729; PMCID: PMC219104.
    478. Novotny MJ, Frederickson WL, Waygood EB, Saier MH. Allosteric regulation of glycerol kinase by enzyme IIIglc of the phosphotransferase system in Escherichia coli and Salmonella typhimurium. J Bacteriol. 1985 May; 162(2):810-6. PMID: 2985549; PMCID: PMC218925.
    479. Grenier FC, Hayward I, Novotny MJ, Leonard JE, Saier MH. Identification of the phosphocarrier protein enzyme IIIgut: essential component of the glucitol phosphotransferase system in Salmonella typhimurium. J Bacteriol. 1985 Mar; 161(3):1017-22. PMID: 3882659; PMCID: PMC215000.
    480. Saier MH, Grenier FC, Lee CA, Waygood EB. Evidence for the evolutionary relatedness of the proteins of the bacterial phosphoenolpyruvate:sugar phosphotransferase system. J Cell Biochem. 1985; 27(1):43-56. PMID: 3884637.
      View in: PubMed
    481. Grenier FC, Waygood EB, Saier MH. Bacterial phosphotransferase system: regulation of mannitol enzyme II activity by sulfhydryl oxidation. Biochemistry. 1985 Jan 01; 24(1):47-51. PMID: 3888258.
      View in: PubMed
    482. Reizer J, Novotny MJ, Hengstenberg W, Saier MH. Properties of ATP-dependent protein kinase from Streptococcus pyogenes that phosphorylates a seryl residue in HPr, a phosphocarrier protein of the phosphotransferase system. J Bacteriol. 1984 Oct; 160(1):333-40. PMID: 6434522; PMCID: PMC214721.
    483. Novotny MJ, Reizer J, Esch F, Saier MH. Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli. J Bacteriol. 1984 Sep; 159(3):986-90. PMID: 6384188; PMCID: PMC215757.
    484. Reizer J, Novotny MJ, Stuiver I, Saier MH. Regulation of glycerol uptake by the phosphoenolpyruvate-sugar phosphotransferase system in Bacillus subtilis. J Bacteriol. 1984 Jul; 159(1):243-50. PMID: 6429122; PMCID: PMC215620.
    485. Sarno MV, Tenn LG, Desai A, Chin AM, Grenier FC, Saier MH. Genetic evidence for glucitol-specific enzyme III, an essential phosphocarrier protein of the Salmonella typhimurium glucitol phosphotransferase system. J Bacteriol. 1984 Mar; 157(3):953-5. PMID: 6365895; PMCID: PMC215355.
    486. Deutscher J, Saier MH. ATP-dependent protein kinase-catalyzed phosphorylation of a seryl residue in HPr, a phosphate carrier protein of the phosphotransferase system in Streptococcus pyogenes. Proc Natl Acad Sci U S A. 1983 Nov; 80(22):6790-4. PMID: 6359157; PMCID: PMC390071.
    487. McRoberts JA, Tran CT, Saier MH. Characterization of low potassium-resistant mutants of the Madin-Darby canine kidney cell line with defects in NaCl/KCl symport. J Biol Chem. 1983 Oct 25; 258(20):12320-6. PMID: 6630190.
      View in: PubMed
    488. Reizer J, Saier MH. Involvement of lactose enzyme II of the phosphotransferase system in rapid expulsion of free galactosides from Streptococcus pyogenes. J Bacteriol. 1983 Oct; 156(1):236-42. PMID: 6413489; PMCID: PMC215075.
    489. Reizer J, Novotny MJ, Panos C, Saier MH. Mechanism of inducer expulsion in Streptococcus pyogenes: a two-step process activated by ATP. J Bacteriol. 1983 Oct; 156(1):354-61. PMID: 6225770; PMCID: PMC215089.
    490. Lee CA, Saier MH. Mannitol-specific enzyme II of the bacterial phosphotransferase system. III. The nucleotide sequence of the permease gene. J Biol Chem. 1983 Sep 10; 258(17):10761-7. PMID: 6309813.
      View in: PubMed
    491. Jacobson GR, Lee CA, Leonard JE, Saier MH. Mannitol-specific enzyme II of the bacterial phosphotransferase system. I. Properties of the purified permease. J Biol Chem. 1983 Sep 10; 258(17):10748-56. PMID: 6350293.
      View in: PubMed
    492. Leonard JE, Saier MH. Mannitol-specific enzyme II of the bacterial phosphotransferase system. II. Reconstitution of vectorial transphosphorylation in phospholipid vesicles. J Biol Chem. 1983 Sep 10; 258(17):10757-60. PMID: 6350294.
      View in: PubMed
    493. Saier MH, Novotny MJ, Comeau-Fuhrman D, Osumi T, Desai JD. Cooperative binding of the sugar substrates and allosteric regulatory protein (enzyme IIIGlc of the phosphotransferase system) to the lactose and melibiose permeases in Escherichia coli and Salmonella typhimurium. J Bacteriol. 1983 Sep; 155(3):1351-7. PMID: 6350268; PMCID: PMC217834.
    494. Lee CA, Saier MH. Use of cloned mtl genes of Escherichia coli to introduce mtl deletion mutations into the chromosome. J Bacteriol. 1983 Feb; 153(2):685-92. PMID: 6401703; PMCID: PMC221685.
    495. Saier MH, Keeler DK, Feucht BU. Physiological desensitization of carbohydrate permeases and adenylate cyclase to regulation by the phosphoenolpyruvate:sugar phosphotransferase system in Escherichia coli and Salmonella typhimurium. Involvement of adenosine cyclic 3',5'-phosphate and inducer. J Biol Chem. 1982 Mar 10; 257(5):2509-17. PMID: 6277902.
      View in: PubMed
    496. Osumi T, Saier MH. Mechanism of regulation of the lactose permease by the phosphotransferase system in Escherichia coli: evidence for protein-protein interaction. Ann Microbiol (Paris). 1982 Mar-Apr; 133(2):269-73. PMID: 7044217.
      View in: PubMed
    497. Osumi T, Saier MH. Regulation of lactose permease activity by the phosphoenolpyruvate:sugar phosphotransferase system: evidence for direct binding of the glucose-specific enzyme III to the lactose permease. Proc Natl Acad Sci U S A. 1982 Mar; 79(5):1457-61. PMID: 7041121; PMCID: PMC345992.
    498. Dills SS, Schmidt MR, Saier MH. Regulation of lactose transport by the phosphoenolpyruvate-sugar phosphotransferase system in membrane vesicles of Escherichia coli. J Cell Biochem. 1982; 18(2):239-44. PMID: 7040431.
      View in: PubMed
    499. Saier MH, Cox DF, Feucht BU, Novotny MJ. Evidence for the functional association of enzyme I and HPr of the phosphoenolpyruvate-sugar phosphotransferase system with the membrane in sealed vesicles of Escherichia coli. J Cell Biochem. 1982; 18(2):231-8. PMID: 7040430.
      View in: PubMed
    500. Lee CA, Jacobson GR, Saier MH. Plasmid-directed synthesis of enzymes required for D-mannitol transport and utilization in Escherichia coli. Proc Natl Acad Sci U S A. 1981 Dec; 78(12):7336-40. PMID: 6801648; PMCID: PMC349261.
    501. Dills SS, Lee CA, Saier MH. Phosphoenolpyruvate-dependent sugar phosphotransferase activity in Megasphaera elsdenii. Can J Microbiol. 1981 Sep; 27(9):949-52. PMID: 7306882.
      View in: PubMed
    502. Thompson J, Saier MH. Regulation of methyl-beta-d-thiogalactopyranoside-6-phosphate accumulation in Streptococcus lactis by exclusion and expulsion mechanisms. J Bacteriol. 1981 Jun; 146(3):885-94. PMID: 6787017; PMCID: PMC216940.
    503. Saier MH, Schmidt MR. Vectorial and nonvectorial transphosphorylation catalyzed by enzymes II of the bacterial phosphotransferase system. J Bacteriol. 1981 Jan; 145(1):391-7. PMID: 6780516; PMCID: PMC217284.
    504. Saier MH, Schmidt MR, Lin P. Phosphoryl exchange reaction catalyzed by enzyme I of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. Kinetic characterization. J Biol Chem. 1980 Sep 25; 255(18):8579-84. PMID: 6997300.
      View in: PubMed
    505. Rephaeli AW, Saier MH. Substrate specificity and kinetic characterization of sugar uptake and phosphorylation, catalyzed by the mannose enzyme II of the phosphotransferase system in Salmonella typhimurium. J Biol Chem. 1980 Sep 25; 255(18):8585-91. PMID: 6997301.
      View in: PubMed
    506. Saier MH, Feucht BU. Regulation of carbohydrate transport activities in Salmonella typhimurium: use of the phosphoglycerate transport system to energize solute uptake. J Bacteriol. 1980 Feb; 141(2):611-7. PMID: 6988388; PMCID: PMC293666.
    507. Feucht BU, Saier MH. Fine control of adenylate cyclase by the phosphoenolpyruvate:sugar phosphotransferase systems in Escherichia coli and Salmonella typhimurium. J Bacteriol. 1980 Feb; 141(2):603-10. PMID: 6245052; PMCID: PMC293665.
    508. Rephaeli AW, Saier MH. Regulation of genes coding for enzyme constituents of the bacterial phosphotransferase system. J Bacteriol. 1980 Feb; 141(2):658-63. PMID: 6245053; PMCID: PMC293672.
    509. Saier MH. Catalytic activities associated with the enzymes II of the bacterial phosphotransferase system. J Supramol Struct. 1980; 14(3):281-94. PMID: 7012451.
      View in: PubMed
    510. Jacobson GR, Lee CA, Saier MH. Purification of the mannitol-specific enzyme II of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system. J Biol Chem. 1979 Jan 25; 254(2):249-52. PMID: 368051.
      View in: PubMed
    511. Rephaeli AW, Saier MH. Kinetic analyses of the sugar phosphate:sugar transphosphorylation reaction catalyzed by the glucose enzyme II complex of the bacterial phosphotransferase system. J Biol Chem. 1978 Nov 10; 253(21):7595-7. PMID: 359550.
      View in: PubMed
    512. Saier MH, Schmidt MR, Leibowitz M. Cyclic AMP-dependent synthesis of fimbriae in Salmonella typhimurium: effects of cya and pts mutations. J Bacteriol. 1978 Apr; 134(1):356-8. PMID: 206537; PMCID: PMC222255.
    513. Saier MH, Straud H, Massman LS, Judice JJ, Newman MJ, Feucht BU. Permease-specific mutations in Salmonella typhimurium and Escherichia coli that release the glycerol, maltose, melibiose, and lactose transport systems from regulation by the phosphoenolpyruvate:sugar phosphotransferase system. J Bacteriol. 1978 Mar; 133(3):1358-67. PMID: 346569; PMCID: PMC222173.
    514. Saier MH, Feucht BU, Mora WK. Sugar phosphate: sugar transphosphorylation and exchange group translocation catalyzed by the enzyme 11 complexes of the bacterial phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem. 1977 Dec 25; 252(24):8899-907. PMID: 336623.
      View in: PubMed
    515. Saier MH, Cox DF, Moczydlowski EG. Sugar phosphate:sugar transphosphorylation coupled to exchange group translocation catalyzed by the enzyme II complexes of the phosphoenolpyruvate:sugar phosphotransferase system in membrane vesicles of Escherichia coli. J Biol Chem. 1977 Dec 25; 252(24):8908-16. PMID: 336624.
      View in: PubMed
    516. Saier MH. Bacterial phosphoenolpyruvate: sugar phosphotransferase systems: structural, functional, and evolutionary interrelationships. Bacteriol Rev. 1977 Dec; 41(4):856-71. PMID: 339892; PMCID: PMC414030.
    517. Saier MH, Staley JT. Phosphoenolpyruvate:sugar phosphotransferase system in Ancalomicrobium adetum. J Bacteriol. 1977 Aug; 131(2):716-8. PMID: 328495; PMCID: PMC235489.
    518. Tuttle RC, Saier MH. Phosphoprotein phosphatase activity associated with the cytoplasmic membrane of Salmonella typhimurium and Escherichia coli. J Biol Chem. 1977 Jun 25; 252(12):4416-7. PMID: 16933.
      View in: PubMed
    519. Saier MH, Roseman S. Sugar transport. 2nducer exclusion and regulation of the melibiose, maltose, glycerol, and lactose transport systems by the phosphoenolpyruvate:sugar phosphotransferase system. J Biol Chem. 1976 Nov 10; 251(21):6606-15. PMID: 789370.
      View in: PubMed
    520. Simoni RD, Roseman S, Saier MH. Sugar transport. Properties of mutant bacteria defective in proteins of the phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem. 1976 Nov 10; 251(21):6584-97. PMID: 789368.
      View in: PubMed
    521. Castro L, Feucht BU, Morse ML, Saier MH. Regulation of carbohydrate permeases and adenylate cyclase in Escherichia coli. Studies with mutant strains in which enzyme I of the phosphoenolpyruvate:sugar phosphotransferase system is thermolabile. J Biol Chem. 1976 Sep 25; 251(18):5522-7. PMID: 184083.
      View in: PubMed
    522. Rephaeli AW, Saier MH. Effects of crp mutations on adenosine 3',5'-monophosphate metabolism in Salmonella typhimurium. J Bacteriol. 1976 Jul; 127(1):120-7. PMID: 179973; PMCID: PMC233041.
    523. Saier MH, Newman MJ. Direct transfer of the phosphoryl moiety of mannitol 1-phosphate to [14C]mannitol catalyzed by the enzyme II complexes of the phosphoenolpyruvate: mannitol phosphotransferase systems in Spirochaeta aurantia and Salmonella typhimurium. J Biol Chem. 1976 Jun 25; 251(12):3834-7. PMID: 819432.
      View in: PubMed
    524. Saier MH, Simoni RD. Regulation of carbohydrate uptake in gram-positive bacteria. J Biol Chem. 1976 Feb 10; 251(3):893-4. PMID: 1249061.
      View in: PubMed
    525. Saier MH, Feucht BU, Hofstadter LJ. Regulation of carbohydrate uptake and adenylate cyclase activity mediated by the enzymes II of the phosphoenolpyruvate: sugar phosphotransferase system in Escherichia coli. J Biol Chem. 1976 Feb 10; 251(3):883-92. PMID: 765335.
      View in: PubMed
    526. Saier MH, Feucht BU, McCaman MT. Regulation of intracellular adenosine cyclic 3':5'-monophosphate levels in Escherichia coli and Salmonella typhimurium. Evidence for energy-dependent excretion of the cyclic nucleotide. J Biol Chem. 1975 Oct 10; 250(19):7593-601. PMID: 170265.
      View in: PubMed
    527. Saier MH, Feucht BU. Coordinate regulation of adenylate cyclase and carbohydrate permeases by the phosphoenolpyruvate:sugar phosphotransferase system in Salmonella typhimurium. J Biol Chem. 1975 Sep 10; 250(17):7078-80. PMID: 169265.
      View in: PubMed
    528. Saier MH, Wentzel DL, Feucht BU, Judice JJ. A transport system for phosphoenolpyruvate, 2-phosphoglycerate, and 3-phosphoglycerate in Salmonella typhimurium. J Biol Chem. 1975 Jul 10; 250(13):5089-96. PMID: 238977.
      View in: PubMed
    529. Saier MH, Bromberg FG, Roseman S. Characterization of constitutive galactose permease mutants in Salmonella typhimurium. J Bacteriol. 1973 Jan; 113(1):512-4. PMID: 4569699; PMCID: PMC251658.
    530. Saier MH, Roseman S. Inducer exclusion and repression of enzyme synthesis in mutants of Salmonella typhimurium defective in enzyme I of the phosphoenolpyruvate: sugar phosphotransferase system. J Biol Chem. 1972 Feb 10; 247(3):972-5. PMID: 4550766.
      View in: PubMed
    531. Saier MH, Feucht BU, Roseman S. Phosphoenolpyruvate-dependent fructose phosphorylation in photosynthetic bacteria. J Biol Chem. 1971 Dec 25; 246(24):7819-21. PMID: 5002684.
      View in: PubMed
    532. Saier MH, Young WS, Roseman S. Utilization and transport of hexoses by mutant strains of Salmonella typhimurium lacking enzyme I of the phosphoenolpyruvate-dependent phosphotransferase system. J Biol Chem. 1971 Sep 25; 246(18):5838-40. PMID: 4938041.
      View in: PubMed
    533. Saier MH, Simoni RD, Roseman S. The physiological behavior of enzyme I and heat-stable protein mutants of a bacterial phosphotransferase system. J Biol Chem. 1970 Nov 10; 245(21):5870-3. PMID: 4919491.
      View in: PubMed