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    Stephen Adams

    TitleProject Scientist
    SchoolUniversity of California, San Diego
    Address9500 Gilman Drive #0647
    CA La Jolla 92093
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      Collapse Research 
      Collapse Research Activities and Funding
      NIH/NIGMS R01GM086197Sep 30, 2008 - Apr 30, 2021
      Role: Co-Principal Investigator
      NIH/NINDS R01NS027177Apr 1, 1989 - Dec 31, 2017
      Role: Principal Investigator

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Adams S, Mackey MR, Ramachandra R, Palida Lemieux SF, Steinbach P, Bushong EA, Butko MT, Giepmans BN, Ellisman MH, Tsien RY. Multicolor Electron Microscopy for Simultaneous Visualization of Multiple Molecular Species. Cell Chem Biol. 2016 Nov 17; 23(11):1417-1427. PMID: 27818300.
        View in: PubMed
      2. Glasgow HL, Whitney MA, Gross LA, Friedman B, Adams S, Crisp JL, Hussain T, Frei AP, Novy K, Wollscheid B, Nguyen QT, Tsien RY. Laminin targeting of a peripheral nerve-highlighting peptide enables degenerated nerve visualization. Proc Natl Acad Sci U S A. 2016 Oct 20. PMID: 27791138.
        View in: PubMed
      3. Adams S. Roger Y. Tsien (1952-2016). Angew Chem Int Ed Engl. 2016 Nov 02; 55(45):13926-13927. PMID: 27730715.
        View in: PubMed
      4. Adams S, Yang HC, Savariar EN, Aguilera J, Crisp JL, Jones KA, Whitney MA, Lippman SM, Cohen EE, Tsien RY, Advani SJ. Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize. Nat Commun. 2016 Oct 04; 7:13019. PMID: 27698471.
        View in: PubMed
      5. Ngo JT, Adams S, Deerinck TJ, Boassa D, Rodriguez-Rivera F, Palida SF, Bertozzi CR, Ellisman MH, Tsien RY. Click-EM for imaging metabolically tagged nonprotein biomolecules. Nat Chem Biol. 2016 Jun; 12(6):459-65. PMID: 27110681; PMCID: PMC4871776 [Available on 10/25/16].
      6. Kislukhin AA, Xu H, Adams S, Narsinh KH, Tsien RY, Ahrens ET. Paramagnetic fluorinated nanoemulsions for sensitive cellular fluorine-19 magnetic resonance imaging. Nat Mater. 2016 Jun; 15(6):662-8. PMID: 26974409.
        View in: PubMed
      7. Griffin BA, Adams S, Tsien RY. How FlAsH got its sparkle: historical recollections of the biarsenical-tetracysteine tag. Methods Mol Biol. 2015; 1266:1-6. PMID: 25560064.
        View in: PubMed
      8. Waadt R, Hitomi K, Nishimura N, Hitomi C, Adams S, Getzoff ED, Schroeder JI. FRET-based reporters for the direct visualization of abscisic acid concentration changes and distribution in Arabidopsis. Elife. 2014 Apr 15; 3:e01739. PMID: 24737861; PMCID: PMC3985518.
      9. Whitney M, Savariar EN, Friedman B, Levin RA, Crisp JL, Glasgow HL, Lefkowitz R, Adams S, Steinbach P, Nashi N, Nguyen QT, Tsien RY. Ratiometric activatable cell-penetrating peptides provide rapid in vivo readout of thrombin activation. Angew Chem Int Ed Engl. 2013 Jan 02; 52(1):325-30. PMID: 23080482; PMCID: PMC3694763.
      10. Hoffmann C, Gaietta G, Zürn A, Adams S, Terrillon S, Ellisman MH, Tsien RY, Lohse MJ. Fluorescent labeling of tetracysteine-tagged proteins in intact cells. Nat Protoc. 2010 Sep; 5(10):1666-77. PMID: 20885379; PMCID: PMC3086663.
      11. Lin MZ, McKeown MR, Ng HL, Aguilera TA, Shaner NC, Campbell RE, Adams S, Gross LA, Ma W, Alber T, Tsien RY. Autofluorescent proteins with excitation in the optical window for intravital imaging in mammals. Chem Biol. 2009 Nov 25; 16(11):1169-79. PMID: 19942140; PMCID: PMC2814181.
      12. Madani F, Lind J, Damberg P, Adams S, Tsien RY, Gräslund AO. Hairpin structure of a biarsenical-tetracysteine motif determined by NMR spectroscopy. J Am Chem Soc. 2009 Apr 08; 131(13):4613-5. PMID: 19281235; PMCID: PMC2735349.
      13. Adams S, Tsien RY. Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH-EDT2 for fluorescent labeling of tetracysteine-tagged proteins. Nat Protoc. 2008; 3(9):1527-34. PMID: 18772880; PMCID: PMC2843588.
      14. Tour O, Adams S, Kerr RA, Meijer RM, Sejnowski TJ, Tsien RW, Tsien RY. Calcium Green FlAsH as a genetically targeted small-molecule calcium indicator. Nat Chem Biol. 2007 Jul; 3(7):423-31. PMID: 17572670; PMCID: PMC2909385.
      15. Gaietta GM, Giepmans BN, Deerinck TJ, Smith WB, Ngan L, Llopis J, Adams S, Tsien RY, Ellisman MH. Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17777-82. PMID: 17101980; PMCID: PMC1635977.
      16. Giepmans BN, Adams S, Ellisman MH, Tsien RY. The fluorescent toolbox for assessing protein location and function. Science. 2006 Apr 14; 312(5771):217-24. PMID: 16614209.
        View in: PubMed
      17. Sun M, Oakes JL, Ananthanarayanan SK, Hawley KH, Tsien RY, Adams S, Yengo CM. Dynamics of the upper 50-kDa domain of myosin V examined with fluorescence resonance energy transfer. J Biol Chem. 2006 Mar 03; 281(9):5711-7. PMID: 16377637.
        View in: PubMed
      18. Martin BR, Giepmans BN, Adams S, Tsien RY. Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity. Nat Biotechnol. 2005 Oct; 23(10):1308-14. PMID: 16155565.
        View in: PubMed
      19. Hoffmann C, Gaietta G, Bünemann M, Adams S, Oberdorff-Maass S, Behr B, Vilardaga JP, Tsien RY, Ellisman MH, Lohse MJ. A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nat Methods. 2005 Mar; 2(3):171-6. PMID: 15782185.
        View in: PubMed
      20. Ju W, Morishita W, Tsui J, Gaietta G, Deerinck TJ, Adams S, Garner CC, Tsien RY, Ellisman MH, Malenka RC. Activity-dependent regulation of dendritic synthesis and trafficking of AMPA receptors. Nat Neurosci. 2004 Mar; 7(3):244-53. PMID: 14770185.
        View in: PubMed
      21. Babendure JR, Adams S, Tsien RY. Aptamers switch on fluorescence of triphenylmethane dyes. J Am Chem Soc. 2003 Dec 03; 125(48):14716-7. PMID: 14640641.
        View in: PubMed
      22. Tour O, Meijer RM, Zacharias DA, Adams S, Tsien RY. Genetically targeted chromophore-assisted light inactivation. Nat Biotechnol. 2003 Dec; 21(12):1505-8. PMID: 14625562.
        View in: PubMed
      23. Sosinsky GE, Gaietta GM, Hand G, Deerinck TJ, Han A, Mackey M, Adams S, Bouwer J, Tsien RY, Ellisman MH. Tetracysteine genetic tags complexed with biarsenical ligands as a tool for investigating gap junction structure and dynamics. Cell Commun Adhes. 2003 Jul-Dec; 10(4-6):181-6. PMID: 14681013.
        View in: PubMed
      24. Adams S, Campbell RE, Gross LA, Martin BR, Walkup GK, Yao Y, Llopis J, Tsien RY. New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: synthesis and biological applications. J Am Chem Soc. 2002 May 29; 124(21):6063-76. PMID: 12022841.
        View in: PubMed
      25. Gaietta G, Deerinck TJ, Adams S, Bouwer J, Tour O, Laird DW, Sosinsky GE, Tsien RY, Ellisman MH. Multicolor and electron microscopic imaging of connexin trafficking. Science. 2002 Apr 19; 296(5567):503-7. PMID: 11964472.
        View in: PubMed
      26. Adams S, Lev-Ram V, Tsien RY. A new caged Ca2+, azid-1, is far more photosensitive than nitrobenzyl-based chelators. Chem Biol. 1997 Nov; 4(11):867-78. PMID: 9384535.
        View in: PubMed
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